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Receptor
PDB id Resolution Class Description Source Keywords
1LOO 2.2 Å EC: 6.3.4.4 CRYSTAL STRUCTURE OF THE MOUSE-MUSCLE ADENYLOSUCCINATE SYNTH LIGATED WITH GTP MUS MUSCULUS PURINE BIOSYNTHESIS LIGASE GTP-BINDING
Ref.: IMP, GTP, AND 6-PHOSPHORYL-IMP COMPLEXES OF RECOMBI MOUSE MUSCLE ADENYLOSUCCINATE SYNTHETASE. J.BIOL.CHEM. V. 277 26779 2002
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GTP A:458;
Valid;
none;
submit data
523.18 C10 H16 N5 O14 P3 c1nc2...
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1IWE 2.1 Å EC: 6.3.4.4 IMP COMPLEX OF THE RECOMBINANT MOUSE-MUSCLE ADENYLOSUCCINATE SYNTHETASE MUS MUSCULUS PURINE BIOSYNTHESIS LIGASE GTP-BINDING
Ref.: IMP, GTP, AND 6-PHOSPHORYL-IMP COMPLEXES OF RECOMBI MOUSE MUSCLE ADENYLOSUCCINATE SYNTHETASE. J.BIOL.CHEM. V. 277 26779 2002
Members (7)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 1IWE - IMP C10 H13 N4 O8 P c1nc2c(n1[....
2 1LON - HDA C3 H5 N O4 C(C(=O)O)N....
3 1MF0 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
4 2DGN - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
5 1LOO - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
6 1MEZ - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
7 1LNY - IMO C10 H14 N4 O11 P2 c1nc2c(c(n....
70% Homology Family (7)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 1IWE - IMP C10 H13 N4 O8 P c1nc2c(n1[....
2 1LON - HDA C3 H5 N O4 C(C(=O)O)N....
3 1MF0 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
4 2DGN - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
5 1LOO - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
6 1MEZ - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
7 1LNY - IMO C10 H14 N4 O11 P2 c1nc2c(c(n....
50% Homology Family (23)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 1HOO - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
2 1NHT - HDA C3 H5 N O4 C(C(=O)O)N....
3 1GIM - HDA C3 H5 N O4 C(C(=O)O)N....
4 1CIB - HDA C3 H5 N O4 C(C(=O)O)N....
5 1QF4 ic50 = 0.665 uM RPD C13 H22 N3 O13 P C(C[C@H](C....
6 1CH8 - HDA C3 H5 N O4 C(C(=O)O)N....
7 1CG0 - HDA C3 H5 N O4 C(C(=O)O)N....
8 1CG1 - HDA C3 H5 N O4 C(C(=O)O)N....
9 2GCQ Ki = 17 uM HDA C3 H5 N O4 C(C(=O)O)N....
10 1HON - GNH C10 H16 N6 O10 P2 c1nc2c(n1[....
11 1CG4 - IMO C10 H14 N4 O11 P2 c1nc2c(c(n....
12 1CG3 - HDA C3 H5 N O4 C(C(=O)O)N....
13 1QF5 ic50 = 0.043 uM RPL C13 H22 N3 O13 P C(C[C@@H](....
14 1HOP - GCP C11 H18 N5 O13 P3 c1nc2c(n1[....
15 5I34 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
16 1P9B - HDA C3 H5 N O4 C(C(=O)O)N....
17 1IWE - IMP C10 H13 N4 O8 P c1nc2c(n1[....
18 1LON - HDA C3 H5 N O4 C(C(=O)O)N....
19 1MF0 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
20 2DGN - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
21 1LOO - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
22 1MEZ - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
23 1LNY - IMO C10 H14 N4 O11 P2 c1nc2c(c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GTP; Similar ligands found: 156
No: Ligand ECFP6 Tc MDL keys Tc
1 GTP 1 1
2 GP3 0.921053 0.973684
3 GDP 0.909091 1
4 GSP 0.853659 0.948718
5 GNH 0.82716 0.986667
6 G1R 0.819277 0.986667
7 GAV 0.811765 0.961039
8 9GM 0.809524 0.973684
9 GNP 0.809524 0.973684
10 GCP 0.797619 0.973684
11 5GP 0.797468 0.986486
12 G 0.797468 0.986486
13 GMV 0.764706 0.973684
14 G2R 0.764045 0.961039
15 G5P 0.755319 0.973684
16 GTG 0.752688 0.936709
17 G2P 0.747126 0.961039
18 G3A 0.744681 0.973684
19 GDD 0.741935 0.961039
20 GDC 0.741935 0.961039
21 GKE 0.741935 0.961039
22 0O2 0.736264 0.986486
23 GP2 0.729412 0.961039
24 6CK 0.726316 0.936709
25 Y9Z 0.723404 0.902439
26 GPG 0.717391 0.961039
27 GFB 0.715789 0.961039
28 GDR 0.715789 0.961039
29 GPD 0.704082 0.925
30 GKD 0.693878 0.961039
31 JB2 0.693878 0.961039
32 GDX 0.686869 0.973684
33 ALF 5GP 0.685393 0.888889
34 GH3 0.681319 0.973333
35 YGP 0.677083 0.901235
36 G3D 0.67033 0.986486
37 GDP AF3 0.659574 0.888889
38 ALF GDP 0.659574 0.888889
39 GDP ALF 0.659574 0.888889
40 DGT 0.659341 0.923077
41 GMP 0.658228 0.88
42 G4P 0.655914 0.986486
43 JB3 0.653846 0.948718
44 NGD 0.647619 0.961039
45 CAG 0.642202 0.880952
46 2MD 0.62963 0.891566
47 MGP 0.619565 0.961039
48 U2G 0.616822 0.936709
49 6G0 0.612903 0.961039
50 MGD 0.612613 0.891566
51 TPG 0.608696 0.840909
52 CG2 0.605505 0.936709
53 GDP 7MG 0.601942 0.911392
54 FEG 0.601852 0.879518
55 G G 0.598039 0.948052
56 ZGP 0.59633 0.869048
57 PGD 0.591304 0.925
58 MD1 0.591304 0.891566
59 3GP 0.590909 0.946667
60 GPX 0.581633 0.946667
61 DGI 0.580645 0.923077
62 IDP 0.576087 0.972973
63 DBG 0.567797 0.948718
64 2GP 0.555556 0.96
65 FE9 0.555556 0.776596
66 G4M 0.547619 0.880952
67 BGO 0.544643 0.924051
68 GCP G 0.543689 0.921053
69 ATP 0.537634 0.92
70 HEJ 0.537634 0.92
71 G1G 0.533898 0.925
72 AQP 0.531915 0.92
73 5FA 0.531915 0.92
74 A G 0.525862 0.935065
75 G A A A 0.525862 0.923077
76 U A G G 0.521368 0.935065
77 HFD 0.520833 0.873418
78 R5I 0.520408 0.946667
79 R7I 0.520408 0.946667
80 01G 0.518868 0.902439
81 P2G 0.510638 0.883117
82 ITT 0.510638 0.868421
83 AKW 0.504348 0.890244
84 GGM 0.504274 0.901235
85 G1R G1R 0.504065 0.924051
86 DGP 0.5 0.910256
87 PGD O 0.5 0.850575
88 MGO 0.5 0.864198
89 DG 0.5 0.910256
90 P1G 0.5 0.871795
91 GTA 0.495495 0.936709
92 PRT 0.490741 0.959459
93 B4P 0.489362 0.894737
94 AP5 0.489362 0.894737
95 IMP 0.489362 0.959459
96 G U 0.487179 0.9
97 7DT 0.484536 0.906667
98 GPC 0.479339 0.879518
99 G C 0.478992 0.9
100 BA3 0.478723 0.894737
101 ADP 0.473684 0.92
102 G2Q 0.471698 0.961039
103 6YZ 0.470588 0.896104
104 G7M 0.46875 0.948052
105 C1Z 0.462963 0.986486
106 25L 0.458716 0.907895
107 A2D 0.457447 0.894737
108 RGT 0.45045 0.909091
109 AGS 0.45 0.873418
110 SAP 0.45 0.873418
111 SGP 0.44898 0.82716
112 A4P 0.445378 0.869048
113 G G G RPC 0.442623 0.875
114 ANP 0.441176 0.896104
115 ACQ 0.441176 0.896104
116 8GT 0.441176 0.875
117 APC G U 0.44 0.886076
118 AT4 0.438776 0.884615
119 G U34 0.438017 0.888889
120 6AD 0.436893 0.841463
121 G G G C 0.433071 0.9125
122 UP5 0.432203 0.873418
123 PCG 0.431373 0.933333
124 C2E 0.431373 0.921053
125 35G 0.431373 0.933333
126 A G C C 0.429688 0.911392
127 T99 0.427184 0.884615
128 5GP 5GP 0.427184 0.883117
129 TAT 0.427184 0.884615
130 AR6 0.425743 0.894737
131 APR 0.425743 0.894737
132 7DD 0.424242 0.906667
133 AN2 0.424242 0.907895
134 DG DG 0.423423 0.865854
135 AD9 0.421569 0.896104
136 M33 0.42 0.883117
137 7D4 0.42 0.835443
138 UCG 0.419847 0.911392
139 HDV 0.419048 0.825
140 H6Y 0.419048 0.946667
141 G C C C 0.416667 0.924051
142 ACP 0.415842 0.896104
143 T5A 0.414634 0.802326
144 A1R 0.412844 0.839506
145 ADQ 0.412844 0.871795
146 MGQ 0.412844 0.935897
147 A3R 0.412844 0.839506
148 MGT 0.411215 0.823529
149 A G U 0.410072 0.888889
150 93A 0.41 0.833333
151 A22 0.407407 0.907895
152 CA0 0.405941 0.896104
153 ATF 0.40566 0.884615
154 AGO 0.404762 0.888889
155 MGV 0.401786 0.890244
156 CGP 0.4 0.86747
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1IWE; Ligand: IMP; Similar sites found with APoc: 496
This union binding pocket(no: 1) in the query (biounit: 1iwe.bio1) has 40 residues
No: Leader PDB Ligand Sequence Similarity
1 3FKQ ATP 1.07239
2 6C90 ADP 1.09409
3 6AU6 GDP 1.32626
4 1TQ4 GDP 1.45278
5 2IS6 ADP 1.53173
6 2FAH GDP 1.53173
7 5IRR GSP 1.62338
8 3DZD ADP 1.63043
9 5H7J GCP 1.75055
10 1OYY AGS 1.75055
11 5LTJ ADP 1.75055
12 1G16 GDP 1.76471
13 1MKY GDP 1.82232
14 1AFS TES 1.85759
15 5CK5 GDP 1.89873
16 2ZFI ADP 1.91257
17 2I4I AMP 1.91847
18 4KVA GTP 1.94175
19 4NCN GTP 1.96937
20 4ZKD GDP 1.96937
21 1XKV ATP 1.96937
22 3TBK ANP 1.96937
23 1YQT ADP 1.96937
24 3LRE ADP 1.97183
25 2CDN ADP 1.99005
26 1WF3 GNP 1.99336
27 1ZJ6 G3D 2.13904
28 2NCD ADP 2.14286
29 2BME GNP 2.15054
30 4R43 GDP 2.18818
31 2ZPA ADP 2.18818
32 4ZNL BEF ADP 2.18978
33 1MR3 G3D 2.20994
34 2RCN GDP 2.23464
35 1SQ5 ADP 2.27273
36 1VHT BA3 2.29358
37 5AHO TLA 2.38095
38 4PX9 ADP 2.39726
39 1G7S GDP 2.407
40 4A4Z ANP 2.407
41 3BER AMP 2.40964
42 4H1V GNP 2.43902
43 1TAD GDP 2.46914
44 1TAD ALF 2.46914
45 3MD0 GDP 2.53521
46 4M9Q GNP 2.64317
47 1IZC PYR 2.65487
48 1ZD9 GDP 2.65957
49 1LVW TYD 2.71186
50 3TK1 GDP 2.72727
51 1KY3 GDP 2.74725
52 4TTQ ATP 2.7907
53 1GOJ ADP 2.8169
54 5KSZ GCP 2.83019
55 1WDT GTP 2.84464
56 6A20 ADP 2.84464
57 5TSH ADP 2.84464
58 5TSH ANP 2.84464
59 5W76 GDP 2.85714
60 2ZR9 DTP 2.86533
61 5ZBR ANP 2.93333
62 2C77 GNP 2.96296
63 2C78 GNP 2.96296
64 3TKL GTP 2.99625
65 1TUU AMP 3.00752
66 1TUU PIS 3.00752
67 1YRB GDP 3.05344
68 5W75 GDP 3.06122
69 4AG5 ADP 3.06122
70 2GK6 ADP 3.06346
71 4ZDJ UTP 3.06346
72 3ZQ6 ADP ALF 3.08642
73 1G6H ADP 3.11284
74 2O0J ADP 3.11688
75 3WXM GTP 3.13199
76 5KUT GDP 3.1746
77 4TMZ GSP 3.18841
78 3SBD GNP 3.20856
79 5W7Q GDP 3.21716
80 3VX3 ADP 3.22581
81 4DKX GDP 3.24074
82 3NHB ADP 3.26797
83 4IHQ ADP 3.28228
84 4YJ1 ADP 3.28228
85 1ION ADP 3.29218
86 4LPS GDP 3.30579
87 1FZQ GDP 3.31492
88 3SFV GDP 3.31492
89 5K0A FAD 3.33333
90 3E5H GNP 3.37079
91 1S8F GDP 3.38983
92 2XTZ GSP 3.38983
93 6G14 G4P 3.40136
94 4BQS ADP 3.40909
95 2A5F GTP 3.42857
96 1F9V ADP 3.45821
97 5WC2 ADP 3.47222
98 5FG3 GDP 3.50109
99 2ZJ5 ADP 3.50109
100 3EZ2 ADP 3.51759
101 4LC1 GDP 3.56083
102 4KBF AMP 3.56164
103 5E95 GDP 3.57143
104 5JCP GDP ALF 3.57995
105 6D5M GNP 3.59281
106 6D5V GNP 3.59281
107 6BVJ GNP 3.59281
108 1NVV GNP 3.61446
109 1WQ1 GDP 3.61446
110 1V8K ANP 3.65854
111 3WYA GDP 3.68664
112 3WY9 GDP 3.68664
113 3N5C GDP 3.7037
114 3PCR GTP 3.7037
115 4JLV ADP 3.71747
116 2FSH ANP 3.71991
117 4DCT GDP 3.72807
118 2VWT PYR 3.74532
119 5GOE GDP 3.79147
120 1FP6 ADP 3.80623
121 4FRZ ADP 3.88601
122 4P4T GDP 3.88889
123 1PUJ GNP 3.90071
124 2Y8E GNP 3.91061
125 4U5X GNP 3.93258
126 1XMV ADP 3.93258
127 2AWN ADP 3.93701
128 5HCN GCP 3.93873
129 6B4K ANP 3.95349
130 2HF9 GSP 3.9823
131 5XKT GNP 4
132 4XGU ADP 4.00943
133 2F9L GDP 4.0201
134 4R98 GNH 4.05904
135 2FFQ GSP 4.09357
136 4U00 ADP 4.09836
137 4J0Q GDP 4.15704
138 2OG2 MLI 4.17827
139 2A5J GDP 4.18848
140 1OIV GDP 4.18848
141 1OIX GDP 4.18848
142 5KDO GDP 4.18994
143 1VKJ A3P 4.21053
144 2WJH GDP 4.21687
145 2WJH FLC 4.21687
146 3Q9L ATP 4.23077
147 1SVK ALF GDP 4.24929
148 5GVR LMR 4.2735
149 1D5C GDP 4.32099
150 1YZN GNP 4.32432
151 2OFW ADX 4.32692
152 3ZUY TCH 4.33437
153 3AQ4 GDP 4.34783
154 3B7G ANP 4.34783
155 2ZEJ GDP 4.34783
156 1Y63 ADP 4.34783
157 3P4X ADP 4.35835
158 3ZFD ANP 4.37637
159 4B47 GDP 4.40771
160 1ZCB GDP 4.41989
161 1CS4 GSP 4.44444
162 5JCZ GDP 4.46927
163 2VAR KDG 4.47284
164 2VAR KDF 4.47284
165 4LX0 BEF GDP 4.51977
166 4BAS GNP 4.52261
167 5N69 ADP 4.52261
168 1LVG ADP 4.54545
169 1R0X ATP 4.54545
170 1Y3A GDP 4.55927
171 2CFI ZZZ 4.55927
172 5UQW GDP 4.59519
173 3IO3 ADP 4.5977
174 3COB ADP 4.60705
175 4YLG GDP 4.62428
176 2C5L GTP 4.62428
177 2CBZ ATP 4.64135
178 3Q85 GNP 4.73373
179 3RAB GNP 4.73373
180 1Z06 GNP 4.7619
181 1BH2 GSP 4.7619
182 1D2E GDP 4.78589
183 4PJ3 ANP 4.814
184 2GKS ADP 4.814
185 1WA5 GTP 4.814
186 4RD0 GDP 4.81928
187 2J59 GTP 4.81928
188 1O3Y GTP 4.81928
189 2QN6 GDP 4.83092
190 4E03 ADP 4.85437
191 2BCG GDP 4.85437
192 1GOT GDP 4.85714
193 6DEF GCP 4.85933
194 2FH5 GTP 4.86486
195 1RE0 GDP 4.87805
196 1S9D GDP 4.87805
197 2B8W ALF 5GP 4.87805
198 2OBM ADP 4.89914
199 3CPJ GDP 4.93274
200 3B9Q MLI 4.96689
201 2EFE GNH 4.97238
202 1UPT GTP 5
203 3IIJ ADP 5
204 3UIE ANP 5
205 5ZXD ATP 5.03282
206 2WHX ADP 5.03282
207 2Z5F A3P 5.03356
208 4V03 ADP 5.05837
209 5XC5 GTP 5.11364
210 5L3R GCP 5.11945
211 1H65 GDP 5.18518
212 1QO0 BMD 5.19481
213 5L3W GDP 5.22876
214 2XZ9 PYR 5.24691
215 4HI0 GDP 5.28302
216 5FTB ANP 5.31178
217 1RZM E4P 5.32544
218 1Z2A GDP 5.35714
219 1KSH GDP 5.37634
220 6D59 GNP 5.38922
221 6D56 GNP 5.38922
222 6BVI GNP 5.38922
223 6D5L GNP 5.38922
224 6D55 GNP 5.38922
225 6BVM GNP 5.38922
226 6D5E GNP 5.38922
227 6D5G GNP 5.38922
228 6BVK GNP 5.38922
229 6D5J GNP 5.38922
230 6BVL GNP 5.38922
231 6D5H GNP 5.38922
232 4GOJ GNP 5.41667
233 1RYH GNP 5.41872
234 4PPF FLC 5.42857
235 5TCI MLI 5.43478
236 1FQK GDP 5.44218
237 2WIC GNP 5.61798
238 1X1R GDP 5.61798
239 2IYL GDP 5.6338
240 1RJ9 GCP 5.66667
241 2ODE ALF GDP 5.67376
242 5MZN ADP 5.68928
243 1KO8 6PG 5.71429
244 1SKQ GDP 5.74713
245 2NGR GDP 5.75916
246 1GRN GDP 5.75916
247 2WMO GTP 5.78947
248 5H7K GDP 5.79345
249 2GJ8 ALF GDP 5.81395
250 3T34 GDP 5.83333
251 4CVN ADP 5.83942
252 5SZH GNP 5.88235
253 3U6B GDP 5.9081
254 2HCJ GDP 5.9081
255 5JBQ GDP 5.9081
256 4G5G GDP 5.9081
257 1D8T GDP 5.9081
258 3U6K GDP 5.9081
259 2BVN GNP 5.9081
260 1IHU AF3 5.9081
261 1IHU ADP 5.9081
262 1MH1 GNP 5.91398
263 4DID GDP 5.92105
264 2W2X GSP 5.94595
265 1G4U GDP 5.97826
266 5OEC GDP 6.01093
267 3T1O GDP 6.06061
268 3T5G GDP 6.07735
269 3CNL GNP 6.10687
270 5O74 GDP 6.11111
271 3DDC GNP 6.13497
272 3IUY AMP 6.14035
273 1Z0F GDP 6.14525
274 1BG2 ADP 6.15385
275 5MVR ADP 6.17284
276 2FJU GSP 6.17978
277 6BSX GDP 6.17978
278 6BSX E7S 6.17978
279 4WZ6 ATP 6.2069
280 1NF3 GNP 6.25
281 1HE1 GDP 6.25
282 3DOE GTP 6.25
283 6CS8 F9Y 6.27063
284 4D0G GTP 6.28571
285 3NKV GNP 6.28571
286 5KSP GDP 6.31579
287 4YS0 ADP 6.34573
288 4LYA ATP 6.34573
289 5L3V GDP 6.35452
290 5L3S GNP 6.37584
291 4PC3 GDP 6.38298
292 1YZQ GNP 6.47059
293 1Z08 GNP 6.47059
294 3RWO GDP 6.48649
295 1YVD GNP 6.50888
296 5LB3 ADP 6.51685
297 1M7B GTP 6.52174
298 4C4P GNP 6.54206
299 4YC7 GNP 6.56455
300 1QHH ATP 6.58683
301 3Q72 GNP 6.62651
302 3REF GDP 6.70103
303 1U0J ADP 6.74157
304 5U32 GDP 6.77966
305 1GWN GTP 6.82927
306 1E96 GTP 6.89655
307 5M04 GDP 6.94444
308 2A9K GDP 6.95187
309 6AIC AMP 7.00935
310 1TU3 GNP 7.01754
311 4QM7 GTP 7.01754
312 2GWH A3P 7.04698
313 1R2Q GNP 7.05882
314 3MJH GTP 7.14286
315 3PQC GDP 7.17949
316 3X1Z GNP 7.18563
317 4HDO GNP 7.18563
318 4HDQ GNP 7.18563
319 1YTM ATP 7.22101
320 4IOK XPO 7.22101
321 3FWY ADP 7.32484
322 3W5J GDP 7.35294
323 1G7C 5GP 7.44681
324 2GCO GNP 7.46269
325 2GCN GDP 7.46269
326 2J0V GDP 7.54717
327 1F6B GDP 7.57576
328 1I4D GDP 7.58929
329 1DAR GDP 7.65864
330 5J1J ANP 7.7193
331 1U8Z GDP 7.7381
332 3A1S GDP 7.75194
333 1OW3 GDP 7.77202
334 3KJI ADP 7.87402
335 4KFU ACP 8.01887
336 1T5C ADP 8.02292
337 1KK1 GNP 8.04878
338 5IRC GDP 8.06452
339 1W0J ADP 8.09628
340 4D0N GDP 8.10811
341 6BC0 GSP 8.10811
342 3LXR GDP 8.10811
343 6BCA GSP 8.10811
344 5HPY GDP 8.10811
345 4RZ3 ADP 8.13559
346 1SVI GDP 8.20513
347 1EK0 GNP 8.23529
348 1CXZ GSP 8.24176
349 3VMF GTP 8.31099
350 4DN8 BMA 8.33333
351 4XSH GSP 8.37989
352 2KIN ADP 8.40336
353 1M2O GNP 8.42105
354 4KVG GTP 8.46154
355 1TX4 ALF GDP 8.47458
356 1Z0J GTP 8.47458
357 2Y65 ADP 8.49315
358 1R6B ADP 8.53392
359 5DI3 GNP 8.64865
360 3DC4 ADP 8.72093
361 2PZE ATP 8.73362
362 1ZC3 GNP 8.84956
363 2CJW GDP 8.85417
364 1A4R GNH 8.90052
365 1A4R GDP 8.90052
366 2EW1 GNP 8.95522
367 4ZI2 GNP 9.02256
368 5LEF GTP 9.09091
369 2W83 GTP 9.09091
370 4ITR GDP 9.17722
371 1LFD GNP 9.1954
372 1DS6 GDP 9.44444
373 3E70 GDP 9.45122
374 1FQJ GDP 9.52381
375 1FQJ ALF 9.52381
376 3T12 GDP ALF 9.55882
377 3BFV ADP 9.5941
378 4M3P HCS 9.60591
379 3EWA ANP 9.62733
380 3EC1 GDP 9.7561
381 3DKP ADP 9.79592
382 3M1I GTP 9.84683
383 6CRK GDP 9.85915
384 1GP2 GDP 9.85915
385 2XT3 ADP 9.88372
386 4KAX GTP 9.93789
387 1YZG GDP 10.0559
388 1NRJ GTP 10.1266
389 1HTW ADP 10.1266
390 1VG0 GDP 10.1449
391 1VG8 GNP 10.1449
392 2WKQ GTP 10.241
393 2CE7 ADP 10.2845
394 1R4A GNP 10.303
395 5EE5 GTP 10.3286
396 1Z0A GDP 10.3448
397 3QBT GNP 10.3448
398 3TNF GNP 10.3448
399 3CX8 GSP 10.3448
400 3H4S ADP 10.3704
401 4NON GDP 10.3846
402 1XX6 ADP 10.4712
403 5WDR GNP 10.5263
404 2G77 GDP 10.6061
405 1KAO GDP 10.7784
406 3QMN A3P 10.8527
407 6BCB GSP 10.9589
408 2V7Q ATP 10.9589
409 2CK3 ANP 10.9589
410 2V7Q ADP 10.9589
411 5OCG GNP 11.1111
412 2VVG ADP 11.1429
413 4V0K GDP 11.2426
414 1VG1 GDP 11.3514
415 5TB5 GDP 11.3514
416 1VG9 GDP 11.3514
417 5TAR GDP 11.3514
418 1M7G AV2 11.3744
419 2PL3 ADP 11.4407
420 4P3Y GDP 11.5385
421 2PEZ DAT 11.7318
422 3BC1 GNP 11.8644
423 5Z2M GTP 11.9318
424 4K81 GTP 12.0155
425 6FA4 GNP 12.1387
426 2X77 GDP 12.1693
427 3KUD GDP 12.3457
428 1GUA GNP 12.3457
429 5YT0 GDP 12.3626
430 5O2T GSP 12.426
431 4XTR ADP 12.4294
432 4XTR ATP 12.4294
433 3ZS9 ADP ALF 12.4294
434 4XVU ATP 12.4294
435 2J9L ATP 12.4324
436 2D7D ADP 12.5
437 2HT6 GDP 12.6437
438 1JJ7 ADP 12.6923
439 2XTN GTP 12.8205
440 3DEF GDP 12.9771
441 3WYF GTP 13.0252
442 3HRD NIO 13.125
443 1UAD GNP 13.1313
444 1GXU 2HP 13.1868
445 2WJG GDP 13.2979
446 1G3Q ADP 13.5021
447 1KMQ GNP 14.1304
448 3A4M ADP 14.2308
449 2QTV GNP 14.2857
450 1KK8 BEF ADP 14.2857
451 4XOI GTP 14.4444
452 1JJV ATP 14.5631
453 3AB3 GDP 14.6341
454 1FTH A3P 14.7541
455 5UWR GNP 16.0338
456 5UWI GNP 16.0338
457 5UWJ GNP 16.0338
458 5DI9 GNP 16.0338
459 5UWQ GNP 16.0338
460 5UWS GNP 16.0338
461 5DIF GNP 16.0338
462 5DHF GNP 16.0338
463 5UWH GNP 16.0338
464 5UWO GNP 16.0338
465 5UWW GNP 16.0338
466 5UWT GNP 16.0338
467 6CIT GNP 16.0338
468 5UWU GNP 16.0338
469 1AQU A3P 16.1616
470 2OM2 GDP 16.6667
471 3GJ3 GDP 17.1946
472 3GJ7 GDP 17.1946
473 3GJ4 GDP 17.1946
474 3GJ0 GDP 17.1946
475 3GJ8 GDP 17.1946
476 3GJ5 GDP 17.1946
477 2UZI GTP 17.3077
478 2W58 ADP 17.3267
479 1Z0K GTP 17.3913
480 5BXQ GDP 17.5926
481 3GJX GTP 17.5926
482 1IBR GNP 17.5926
483 4HAT GNP 17.5926
484 1J2J GTP 17.7778
485 5UIV ADP 18.0617
486 4YMU ATP 19.0909
487 3CH5 GDP 19.2308
488 4LHW GNP 21.8391
489 5UPK GNP 22.9167
490 2HV8 GTP 23.4375
491 3ZIA ADP 23.8095
492 3ZIA ATP 23.8095
493 3WYG GTP 25
494 5WLB GNP 26.4706
495 2D7C GTP 35.7143
496 5UWP GNP 36.8421
Pocket No.: 2; Query (leader) PDB : 1IWE; Ligand: IMP; Similar sites found with APoc: 33
This union binding pocket(no: 2) in the query (biounit: 1iwe.bio1) has 89 residues
No: Leader PDB Ligand Sequence Similarity
1 4KVL PLM 1.09409
2 4OHY ANP 1.16009
3 1QHG ATP 1.31291
4 5YV5 ADP 1.96937
5 6GN6 MAL 2.23714
6 1RRC ADP 2.32558
7 4CNE SAH 2.62172
8 1ON3 DXX 3.28228
9 5FJJ MAN 3.71991
10 4LIK CIT 3.82653
11 3BY9 SIN 3.84615
12 3E4O SIN 3.93443
13 1QJI PKF 4
14 3DDN HPV 4.15755
15 3G2Y GF4 4.18251
16 2CXG GLC GLC 4.37637
17 3R5W F42 4.46429
18 4GOX A3P 4.47284
19 3LN9 FLC 5.03597
20 1B0U ATP 5.34351
21 4CQK PIO 6.38298
22 1LR8 IHS 6.75676
23 2ORV 4TA 7.26496
24 1B7A OPE 7.52688
25 3AJ4 SEP 8.03571
26 4GBM A3P 8.66873
27 1W4R TTP 8.71795
28 2BEK ATP 9.72763
29 2BES RES 9.88372
30 3JQM GTP 10.1911
31 5XQL C2E 10.9966
32 2WOJ ADP ALF 12.4294
33 4URF 1PS 14.1129
Pocket No.: 3; Query (leader) PDB : 1IWE; Ligand: IMP; Similar sites found with APoc: 25
This union binding pocket(no: 3) in the query (biounit: 1iwe.bio1) has 73 residues
No: Leader PDB Ligand Sequence Similarity
1 4Y7E BMA BMA BMA 1.15607
2 5HV7 RBL 1.37615
3 3JDW ORN 2.12766
4 6FAA ADP 2.407
5 2OHH FMN 2.47525
6 4GK9 MAN BMA MAN MAN MAN 2.50896
7 1XP8 AGS 3.00546
8 3GCM 5GP 3.06346
9 3L8H FX1 3.35196
10 5K5Z ANP 4.14013
11 4DDY DN6 4.18251
12 6FRN FMN 4.63415
13 5CPR 539 5.22388
14 5FHD ADP ALF 5.31178
15 3O5N BR0 5.35714
16 3WXL ADP 5.47046
17 4Y9D NAI 5.57377
18 2GDJ ANP 5.68182
19 2Z6I FMN 6.62651
20 4IOK ADP 7.22101
21 4JWF SAH 7.37327
22 4LFL TG6 9.30233
23 1XTT U5P 9.72222
24 1O5O U5P 9.95475
25 2G77 AF3 10.6061
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