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Receptor
PDB id Resolution Class Description Source Keywords
1LSH 1.9 Å NON-ENZYME: BINDING LIPID-PROTEIN INTERACTIONS IN LIPOVITELLIN ICHTHYOMYZON UNICUSPIS LIPOVITELLIN VITELLOGENIN LIPOPROTEIN PLASMA APOLIPOPROTE APOLIPOPROTEIN B APOB MICROSOMAL TRIGLYCERIDE TRANSFER PR BOUNDARY LIPID PHOSPHOLIPID STRUCTURE LIPID BINDING PROTEIN
Ref.: LIPID-PROTEIN INTERACTIONS IN LIPOVITELLIN. BIOCHEMISTRY V. 41 9398 2002
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
PLD A:2001;
A:2002;
A:2004;
A:2005;
A:2006;
A:2007;
B:2003;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
none;
none;
none;
submit data
875.313 C50 H101 N O8 P CCCCC...
UPL A:2008;
A:2009;
A:2011;
A:2012;
A:2013;
A:2014;
A:2015;
A:2017;
A:2018;
A:2019;
A:2020;
A:2022;
A:2024;
A:2025;
A:2026;
A:2029;
A:2030;
A:2032;
A:2034;
A:2035;
A:2036;
A:2037;
A:2038;
A:2039;
A:2040;
A:2041;
A:2042;
A:2047;
A:2048;
A:2050;
B:2010;
B:2016;
B:2021;
B:2023;
B:2027;
B:2028;
B:2031;
B:2033;
B:2043;
B:2044;
B:2045;
B:2046;
B:2049;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
submit data
478.92 C34 H70 CCCCC...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1LSH 1.9 Å NON-ENZYME: BINDING LIPID-PROTEIN INTERACTIONS IN LIPOVITELLIN ICHTHYOMYZON UNICUSPIS LIPOVITELLIN VITELLOGENIN LIPOPROTEIN PLASMA APOLIPOPROTE APOLIPOPROTEIN B APOB MICROSOMAL TRIGLYCERIDE TRANSFER PR BOUNDARY LIPID PHOSPHOLIPID STRUCTURE LIPID BINDING PROTEIN
Ref.: LIPID-PROTEIN INTERACTIONS IN LIPOVITELLIN. BIOCHEMISTRY V. 41 9398 2002
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 510 families.
1 1LSH - PLD C50 H101 N O8 P CCCCCCCCCC....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 391 families.
1 1LSH - PLD C50 H101 N O8 P CCCCCCCCCC....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 298 families.
1 1LSH - PLD C50 H101 N O8 P CCCCCCCCCC....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: PLD; Similar ligands found: 91
No: Ligand ECFP6 Tc MDL keys Tc
1 HGP 1 1
2 PC7 1 1
3 6PL 1 1
4 HGX 1 1
5 LIO 1 1
6 PLD 1 1
7 XP5 0.935484 1
8 PCW 0.871429 0.981481
9 PCK 0.847222 0.946429
10 8PE 0.80303 0.793103
11 PEH 0.80303 0.793103
12 PEF 0.80303 0.793103
13 PTY 0.80303 0.793103
14 PEV 0.80303 0.793103
15 PSC 0.792208 0.981481
16 9PE 0.791045 0.793103
17 PEE 0.764706 0.810345
18 CD4 0.735294 0.727273
19 MC3 0.732394 0.924528
20 PC1 0.732394 0.924528
21 PCF 0.732394 0.924528
22 LHG 0.714286 0.701754
23 PGT 0.714286 0.701754
24 6OU 0.706667 0.779661
25 L9Q 0.706667 0.779661
26 LOP 0.706667 0.779661
27 P5S 0.694444 0.745763
28 LPC 0.685714 0.963636
29 LP3 0.685714 0.963636
30 LAP 0.685714 0.963636
31 3PH 0.681818 0.727273
32 7PH 0.681818 0.727273
33 LPP 0.681818 0.727273
34 F57 0.681818 0.727273
35 6PH 0.681818 0.727273
36 7P9 0.671642 0.727273
37 PX2 0.671642 0.773585
38 PX8 0.671642 0.773585
39 ZPE 0.666667 0.779661
40 CN3 0.657895 0.727273
41 POV 0.65 0.907407
42 L9R 0.65 0.907407
43 GP7 0.638554 0.779661
44 PEK 0.634146 0.779661
45 D3D 0.632911 0.689655
46 PGW 0.632911 0.689655
47 PII 0.631579 0.655738
48 CN6 0.631579 0.727273
49 PD7 0.626866 0.727273
50 DR9 0.625 0.689655
51 PGV 0.625 0.689655
52 P6L 0.617284 0.689655
53 PGK 0.617284 0.666667
54 PIF 0.615385 0.645161
55 44G 0.611111 0.701754
56 OZ2 0.609756 0.689655
57 P50 0.609756 0.745763
58 CDL 0.608108 0.722222
59 42H 0.607595 0.946429
60 PIZ 0.604938 0.655738
61 D21 0.6 0.714286
62 M7U 0.6 0.727273
63 DGG 0.595238 0.666667
64 PSF 0.594595 0.745763
65 43Y 0.594203 0.962264
66 52N 0.592593 0.645161
67 IP9 0.592593 0.655738
68 PIO 0.592593 0.645161
69 3PE 0.592105 0.754386
70 DLP 0.574713 0.907407
71 44E 0.573529 0.727273
72 B7N 0.564706 0.645161
73 8ND 0.56338 0.614035
74 PC5 0.56 0.824561
75 PDK 0.55914 0.777778
76 AGA 0.544304 0.701754
77 EPH 0.537634 0.779661
78 3PC 0.531646 0.90566
79 PIE 0.522727 0.629032
80 P3A 0.505618 0.689655
81 T7X 0.505376 0.645161
82 OPC 0.472527 0.963636
83 LPE 0.467532 0.909091
84 NKN 0.452055 0.696429
85 NKO 0.452055 0.696429
86 CN5 0.451219 0.745455
87 SPU 0.445783 0.803279
88 3XU 0.44086 0.809524
89 OCB 0.438356 0.796296
90 S12 0.41573 0.716667
91 NKP 0.402439 0.684211
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1LSH; Ligand: PLD; Similar sites found with APoc: 134
This union binding pocket(no: 1) in the query (biounit: 1lsh.bio1) has 16 residues
No: Leader PDB Ligand Sequence Similarity
1 5U3F 7TS 2.44565
2 5W4W 9WG 2.71903
3 2VDF OCT 2.7668
4 4NV7 COA 2.88462
5 2IU8 PLM 2.94118
6 2G30 ALA ALA PHE 3.10078
7 5MRH Q9Z 3.1348
8 4CS4 ANP 3.28467
9 4CS4 AXZ 3.28467
10 1COY FAD 3.44828
11 2E5A LAQ 3.45821
12 3KYF 5GP 5GP 3.4632
13 3A16 PXO 3.48525
14 1SDW IYT 3.50318
15 3LKJ LKJ 3.5461
16 1KOR ANP 3.76176
17 1KOR SIN 3.76176
18 1KOR ARG 3.76176
19 1GPM AMP 3.80952
20 3A7R LAQ 3.85757
21 1RYD GLC 3.87597
22 4GLW NMN 3.93443
23 1ZY5 ANP 3.9604
24 4RSL FAD 4.04494
25 2XCG XCG 4.07523
26 4BTV RB3 4.07523
27 6EAC ANP 4.07523
28 4NOS ITU 4.07523
29 1S4M LUM 4.09556
30 6ALW BNV 4.16667
31 4MVK ACE VAL PHE PHE ALA GLU ASP NH2 4.25532
32 5YJS SAL 4.35897
33 4RF7 ARG 4.38871
34 3QWI NAP 4.44444
35 3QWI CUE 4.44444
36 5KJW 53C 4.68384
37 4WBD CIT 4.80591
38 5D9G GLU ASN LEU TYR PHE GLN 4.87805
39 1OUK 084 4.91803
40 2JDR GLY ARG PRO ARG THR THR SER PHE ALA GLU 4.97076
41 2JDR L20 4.97076
42 4K5S FAD 5.01567
43 4K5S PM0 5.01567
44 3CBC DBS 5.05051
45 5BVE 4VG 5.26316
46 4DDY DN6 5.32319
47 2VL1 GLY GLY 5.32915
48 4XTX 590 5.55556
49 3FW4 CAQ 5.61798
50 5TUF TDC 5.62347
51 3E9I XAH 5.64263
52 2Z3U CRR 5.64706
53 5OCG 9R5 5.82011
54 5O3Q CMP 5.83333
55 5TZO 7V7 5.85106
56 4HWS 1B3 5.95611
57 5WO4 B7V 5.96026
58 6GAS FAD 6.0423
59 5G48 1FL 6.26959
60 2QHS OCA 6.32911
61 6FA4 D1W 6.35838
62 1OFL NGK GCD 6.44491
63 1LVL NAD 6.55022
64 3DLG GWE 6.59091
65 4X9X OLA 6.68896
66 5T8U LPA 6.89655
67 2Y8L ADP 6.89655
68 4X7R NTO 6.89655
69 2V92 ATP 6.89655
70 2V92 AMP 6.89655
71 3JQG NAP 6.94444
72 3JQ8 NAP 6.94444
73 4CM9 NAP 6.94444
74 3JQ9 NAP 6.94444
75 3JQF NAP 6.94444
76 3JQB NAP 6.94444
77 4CLR NAP 6.94444
78 3BMQ NAP 6.94444
79 2QHV OC9 7.14286
80 2ORO 228 7.19794
81 1HXD BTN 7.47664
82 1ED4 IPU 7.52351
83 3E7S AT2 7.52351
84 3UH0 TSB 7.52351
85 3H0L ADP 7.53138
86 4MNS 2AX 7.54717
87 2ART LPA AMP 7.63359
88 2QPU QPS 7.65432
89 2QPU QPU 7.65432
90 4WOE ADP 7.68156
91 4RKX 3S9 8.04598
92 1F9V ADP 8.06916
93 4MOB ADP 8.13253
94 5CIC 51R 8.33333
95 3EFS BTN 8.58369
96 4JSR 1NQ 8.77193
97 5ZZ6 NAD 8.77743
98 4WCX MET 8.95833
99 1YB5 NAP 9.11681
100 1TT8 PHB 9.14634
101 6H3O FAD 9.21659
102 3NKS ACJ 9.22432
103 5AYT L6Y 9.43396
104 4DQ2 BTX 9.7561
105 1WPY BTN 9.78723
106 6DZN AE3 9.85915
107 5DYO FLU 9.90566
108 2CJU PHX 10.0313
109 5H9Y BGC BGC BGC BGC 10.1351
110 2DXU BT5 10.2128
111 4YRY NAD 10.6583
112 3A5Y KAA 10.7246
113 3E85 BSU 10.7595
114 5J75 6GQ 11.3636
115 2RDE C2E 11.5538
116 3TCT 3MI 11.811
117 6GNO XDI 11.8519
118 3I3X U22 11.9691
119 1KGI T4A 12.5984
120 3KYG 5GP 5GP 12.7753
121 2AZ5 307 12.8378
122 4RYV ZEA 13.5484
123 5FUI APY 13.6364
124 4IEN GDP 14.1104
125 2AG4 OLA 14.6341
126 2AG4 LP3 14.6341
127 2PNC CLU 17.2414
128 5DQ8 FLF 18.3333
129 5Y4R C2E 20
130 4K55 H6P 20.9677
131 5UKL SIX 20.9677
132 5U98 1KX 23.2323
133 5XLY C2E 24.812
134 3IWD M2T 35.4839
Pocket No.: 2; Query (leader) PDB : 1LSH; Ligand: PLD; Similar sites found with APoc: 17
This union binding pocket(no: 2) in the query (biounit: 1lsh.bio1) has 22 residues
No: Leader PDB Ligand Sequence Similarity
1 4GLW 0XT 3.93443
2 4I90 CHT 4.62046
3 1R6N 434 5.21327
4 1ZDQ MSM 5.35714
5 1KTG AMP 5.7971
6 5W7B MYR 7.0922
7 4PZ6 GMP 7.52351
8 5OF1 SAL 8.09524
9 5LWY OLB 9.34579
10 6EOM ALA LYS 9.40439
11 3HCH RSM 9.58904
12 3ITA AIC 9.71787
13 1KNM LAT 10
14 1JBU BEN 11.1111
15 1DCP HBI 11.5385
16 4LO2 GAL BGC 12.2449
17 4F4S EFO 14.4737
Pocket No.: 3; Query (leader) PDB : 1LSH; Ligand: PLD; Similar sites found with APoc: 27
This union binding pocket(no: 3) in the query (biounit: 1lsh.bio1) has 12 residues
No: Leader PDB Ligand Sequence Similarity
1 3IAE D7K 2.50784
2 4EN4 ATP 2.5641
3 4EN4 GT1 2.5641
4 4EN4 GT0 2.5641
5 4ONQ SFG 2.82132
6 3L2B B4P 2.85714
7 4ITU 1HS 3.125
8 3R96 ACO 3.19149
9 3R96 AMP 3.19149
10 5AAV GW5 4.36508
11 3CV6 HXS 4.64396
12 3CV6 NAP 4.64396
13 5LPA 71R 6.2963
14 5LPA ATP 6.2963
15 5X1M DHB 6.54008
16 5X1M THG 6.54008
17 1Q23 FUA 6.84932
18 5W7B PA1 PO4 FTT FTT GCS FTT PO4 KDO MYR 7.0922
19 5MR6 FAD 7.21003
20 5CSD ACD 7.54717
21 5X4Q 7Z6 8.51064
22 1PS9 FMN 10.5812
23 1QFY FAD 10.7143
24 1QFY NAP 10.7143
25 1YKF NAP 11.6477
26 3KH5 AMP 12.1429
27 3HRD FAD 27.2727
Pocket No.: 4; Query (leader) PDB : 1LSH; Ligand: PLD; Similar sites found with APoc: 51
This union binding pocket(no: 4) in the query (biounit: 1lsh.bio1) has 16 residues
No: Leader PDB Ligand Sequence Similarity
1 4WG0 CHD None
2 3ILR SGN 3.24324
3 3ILR SGN IXD 3.24324
4 3ILR IXD 3.24324
5 1NJJ GET 3.44828
6 6BR8 PGV 3.96825
7 6A0S NDP 4.21687
8 3THR C2F 4.43686
9 5U97 PIT 4.56274
10 4QTB 38Z 4.73684
11 3SJK LYS PRO VAL LEU ARG THR ALA 4.73684
12 4P8K 38C 5.20833
13 4P8K FAD 5.20833
14 4WNK 453 5.35117
15 2Q7D ANP 5.49133
16 1JH7 UVC 5.82011
17 5EW9 5VC 5.90406
18 3KP6 SAL 5.96026
19 4O4Z N2O 6.49351
20 4KBS PX2 6.51163
21 6G9I CXX 6.54762
22 3RS8 ALA TRP LEU PHE GLU ALA 6.58307
23 4WGF HX2 7.31707
24 5DEY 59T 7.40741
25 2VQ5 HBA 7.46269
26 3E3U NVC 8.12183
27 4NAT ADP 8.125
28 2QLX RM4 8.33333
29 2D5X L35 8.90411
30 5LX9 OLB 9.15493
31 3E2M E2M 9.18919
32 5IXH OTP 9.31677
33 4AUT FAD 9.40439
34 3VOZ 04A 9.84127
35 3NT6 COA 9.93031
36 4L4J NAG NAG BMA MAN NAG 9.95475
37 1HG4 LPP 10.0358
38 1PVC ILE SER GLU VAL 14.7059
39 5TVI MYR 15.2174
40 3ND6 ATP 15.7895
41 6MJ7 ARG 16.3636
42 6GMN F4E 17.5258
43 2Y69 CHD 17.5676
44 5Z84 CHD 17.8571
45 5ZCO CHD 17.8571
46 5W97 CHD 17.8571
47 1JGS SAL 19.5652
48 4OGQ 1O2 20.6897
49 5O0B 9FE 20.9877
50 5EOB 5QQ 25.3918
51 1UO4 PIH 29.4118
Pocket No.: 5; Query (leader) PDB : 1LSH; Ligand: PLD; Similar sites found with APoc: 379
This union binding pocket(no: 5) in the query (biounit: 1lsh.bio1) has 11 residues
No: Leader PDB Ligand Sequence Similarity
1 6B79 ORA None
2 5LUN ARG 2.19436
3 1M15 ADP 2.19436
4 1M15 ARG 2.19436
5 3H5N ATP 2.19436
6 5LUN OGA 2.19436
7 3OZ2 OZ2 2.19436
8 6GIN IR2 2.32558
9 4J36 FAD 2.40964
10 2OFV 242 2.52708
11 2XGT NSS 2.52874
12 3UYK 0CX 2.58398
13 1O9J NAD 2.59481
14 2YNE YNE 2.60417
15 2YNE NHW 2.60417
16 2H8H H8H 2.61682
17 5JSD ACY 1GN GAL 1GN BGC ACY GAL BGC 2.64256
18 5JSD 1GN ACY GAL ACY 1GN BGC GAL BGC 2.64256
19 5E3Q SCA 2.64901
20 4KBA 1QM 2.71903
21 5IVE 6E8 2.72727
22 2J3M PRI 2.82132
23 2J3M ATP 2.82132
24 5XIJ 873 2.82132
25 2HQM FAD 2.82132
26 5A3T MMK 2.82132
27 1X7D ORN 2.82132
28 5XIJ ANP 2.82132
29 4I8P NAD 2.88462
30 3RWP ABQ 2.89389
31 2GMH UQ5 2.91096
32 4NFN 2KC 2.91262
33 1KRR ACO 2.95567
34 1SSQ CYS 2.99625
35 5XIO HFG 3.01205
36 1T7Q COA 3.07443
37 1T7Q 152 3.07443
38 5FM0 WAQ 3.07692
39 3HKW IX6 3.09811
40 4PZ2 NAD 3.1348
41 3VRY B43 3.1348
42 2Z5Y HRM 3.1348
43 5KF6 NAD 3.1348
44 4J7H TRH 3.1348
45 4B0T ADP 3.1348
46 4C2C ALA VAL PRO ALA 3.1348
47 4P5Z Q7M 3.1348
48 4J7H TLO 3.1348
49 3IWJ NAD 3.18091
50 4HZD COA 3.19149
51 2IVD ACJ 3.2197
52 3HAZ NAD 3.2967
53 3HAZ FAD 3.2967
54 2GTF P1R 3.33333
55 5IUW NAD 3.42052
56 5IUW IAC 3.42052
57 6B3V ANP 3.42105
58 6B3V 7DQ 3.42105
59 4FAJ LEU VAL THR LEU VAL PHE VAL 3.44828
60 4ZLU 4PW 3.44828
61 1K0E TRP 3.44828
62 3MKH FAD 3.44828
63 6E08 NAP 3.44828
64 5CUO COA 3.46535
65 4TSZ ACE GLN ALC ASP LEU ZCL 3.53261
66 3GD9 GLC BGC BGC BGC 3.54223
67 1KGQ SCO 3.64964
68 1KGQ NPI 3.64964
69 2HK5 1BM 3.7037
70 6HTO MET 3.75
71 6HTO 5AD 3.75
72 3VZ3 NAP 3.76176
73 3VZ3 SSN 3.76176
74 3QSB 743 3.76176
75 4XPQ FUL 3.76176
76 5GXU FAD 3.76176
77 5X5U NAD 3.76238
78 5L2M 6ZY 3.79242
79 5OM2 DXT 3.79404
80 6CC0 EWM 3.79747
81 2QIA U20 3.81679
82 6B2M COA 3.84615
83 4B7P 9UN 3.91304
84 5JIC ADP 4.0293
85 5JIC N7E 4.0293
86 6AM8 PLT 4.0404
87 6AM8 TRP 4.0404
88 6AMI TRP 4.0404
89 2A1L PCW 4.07407
90 5VAD 91Y 4.07523
91 5VAD PRO 4.07523
92 3HXU A5A 4.07523
93 1KY8 NAP 4.07523
94 5LHT TIH 4.08163
95 5UC4 83S 4.09091
96 6CUZ FEV 4.12371
97 1VCE SAH 4.15094
98 1WNG SAH 4.15094
99 5F3I 5UJ 4.16667
100 6ALW BMJ 4.16667
101 2WEI VGG 4.18118
102 1U0A BGC BGC BGC BGC 4.20561
103 5Z46 8XL 4.20712
104 6B5G NAD 4.25963
105 6B5G CQY 4.25963
106 1VJY 460 4.29043
107 4XMF HSM 4.34783
108 4Z87 GDP 4.38095
109 3RHJ NAP 4.38871
110 4GID 0GH 4.38871
111 6C1S EFV 4.38871
112 3NZ1 3NY 4.38871
113 5XVG 8FX 4.43686
114 3FYS PLM 4.44444
115 4I9B NAD 4.44874
116 1ST0 GTG 4.45104
117 1DZK PRZ 4.4586
118 5FP4 YC8 4.49102
119 2YKL NLD 4.62963
120 5L13 6ZE 4.70219
121 1OPK P16 4.70219
122 5UCD NAP 4.70219
123 1T36 U 4.70219
124 3KJM 245 4.70219
125 3A2Q ACA ACA 4.70219
126 2WOX NDP 4.70348
127 4CSV STI 4.72727
128 4U0O MTA 4.72973
129 4V24 GYR 4.85175
130 2YAK OSV 4.91228
131 3PFG SAM 4.94297
132 3PFG TLO 4.94297
133 3TWD GOB 4.95496
134 5KWW 6YA 5.01567
135 5V59 8X1 5.01567
136 5EXW 7DT 5.01567
137 3PP0 03Q 5.02959
138 3FD5 AP2 5.07614
139 2RKV COA 5.09978
140 2RKV ZBA 5.09978
141 4GGL CJC 5.11628
142 3GC8 B45 5.13514
143 3T1A 5MA 5.15098
144 5TPR NAD 5.18018
145 3MQG ACO 5.20833
146 3MQG UDP 5.20833
147 3MQG UDP UDP 5.20833
148 3MVH WFE 5.26316
149 2I7N ACO 5.27778
150 4HK8 XYP XYP XYP XYP XYP XYP 5.29101
151 4DXD 9PC 5.30303
152 4PFC 2QX 5.32915
153 2ZTG A5A 5.32915
154 5VCV 1N1 5.32915
155 5WS9 OXL 5.32915
156 3VBK COA 5.36585
157 3VBK 0FX 5.36585
158 5Y72 DST 5.37313
159 3JZ4 NAP 5.40541
160 6FK3 PPI 5.41045
161 5I60 67W 5.42005
162 3TAY MN0 5.52147
163 4TWP AXI 5.53506
164 3QXV MTX 5.55556
165 4I53 1C1 5.58659
166 5TUF FAD 5.62347
167 4HY1 19X 5.64103
168 3IAL PR8 5.64263
169 5YBN AKG 5.64263
170 4FFG 0U8 5.64263
171 1HV9 COA 5.64263
172 5L2R MLA 5.64263
173 1GT4 UNA 5.66038
174 5UMY TNN 5.71429
175 2OQ2 A3P 5.74713
176 5UGH 8AJ 5.79345
177 1ZM1 BGC BGC BGC 5.80913
178 5DEP UD1 5.81395
179 4K81 GTP 5.84795
180 5HES 032 5.86319
181 5KXQ GDP 5.9322
182 4WHZ 3NL 5.95611
183 3TTI KBI 5.95611
184 2NSX IFM 5.95611
185 4ZUL UN1 5.95611
186 2P7Q GG6 6.01504
187 5ML3 DL3 6.04027
188 5NEA 8V8 6.15385
189 3FP0 FP0 6.1657
190 5LYH 7B8 6.21762
191 3ZJX BOG 6.22837
192 2Y5D NAP 6.26959
193 1YFS ALA 6.26959
194 4NS3 NAD 6.26959
195 2F3R G5P 6.28019
196 3T7V SAM 6.28571
197 5TKJ ALA VAL GLY ILE GLY ALA VAL PHE 6.33484
198 4U0I 0LI 6.34921
199 4IGQ THR M3L GLN 6.38889
200 1UNB PN1 6.43087
201 3P2H NOO 6.46766
202 5XDT ZI7 6.49351
203 2GU8 796 6.52819
204 4WUP 3UF 6.53846
205 1LVG 5GP 6.56566
206 4LGY ADP 6.58307
207 1T90 NAD 6.58436
208 4EMV 0R9 6.63717
209 4WVO 3UZ 6.64653
210 3IES M24 6.71506
211 5JJU AMP 6.76471
212 4K3H 1OM 6.77966
213 4AAW R84 6.89655
214 3OV6 MK0 6.89655
215 2WA4 069 6.89655
216 2J7T 274 6.95364
217 2YYE APC 6.95652
218 4F4P 0SB 6.95971
219 5H9P TD2 6.96203
220 1QKQ MAN 7.04225
221 1QGQ UDP 7.05882
222 5FPX GLY SER SER HIS HIS HIS HIS HIS 7.07965
223 3PE2 E1B 7.12166
224 6CZI 38E 7.14286
225 5AE2 FYC 7.21003
226 5AE2 FAD 7.21003
227 5EJL C2E 7.25806
228 3L5R 47X 7.37705
229 2ZMF CMP 7.40741
230 4Z9D NAD 7.42857
231 2RG0 CTT 7.44186
232 2RCU BUJ 7.52351
233 5MW4 5JU 7.52351
234 4A0M NAD 7.52351
235 4I3V NAD 7.52351
236 5HW4 SAM 7.66129
237 5N87 N66 7.66773
238 6MPT C30 7.69231
239 5ALC TIQ 7.69231
240 2FOJ GLY ALA ARG ALA HIS SER SER 7.74194
241 1MFD GLA MMA ABE 7.76256
242 4USI ATP 7.79221
243 4PYW ACE THR THR ALA ILE NH2 7.83699
244 3IU9 T07 7.98611
245 2CM4 RCL 8
246 4ZU4 4TG 8.10811
247 3G6K FAD 8.11688
248 3G6K POP 8.11688
249 1ZB6 GST 8.14332
250 1ZB6 DIN 8.14332
251 5GM5 CBI 8.15047
252 1FFU CDP 8.15047
253 4NG2 OHN 8.15217
254 2ICK DMA 8.15451
255 3ZLQ 6T9 8.19672
256 1VPM COA 8.28402
257 1KZN CBN 8.29268
258 1D01 ACE MET LEU SER VAL GLU GLU GLU GLY 8.33333
259 4G31 0WH 8.3612
260 1VA6 ADP 8.46395
261 1VA6 P2S 8.46395
262 1KDK DHT 8.47458
263 2GC0 PAN 8.51064
264 2QBU SAH 8.62069
265 4QMN DB8 8.70968
266 5W10 CMP 8.71795
267 6D6L FY4 8.82353
268 1N5S ADL 8.92857
269 5A89 FMN 8.97436
270 5A89 ADP 8.97436
271 5GQF GAL NAG 9.07591
272 5H5A 6OU 9.09091
273 1UYY BGC BGC 9.16031
274 2J9C ATP 9.2437
275 2J9D ADP 9.2437
276 2J9D AMP 9.2437
277 2AGC DAO 9.25926
278 3MTX PGT 9.27152
279 2V1O COA 9.27152
280 4ZSI GLP 9.35672
281 5OVC ACE GLU ALA GLN THR ARG LEU 9.375
282 5N5S NAP 9.40439
283 3FS8 TDR 9.52381
284 3FS8 ACO 9.52381
285 5F6U 5VK 9.55414
286 1NYW DAU 9.64467
287 4U0W 16G 9.7561
288 5MJA 7O3 9.83607
289 4USF 6UI 9.86842
290 5TVA COA 10
291 5TVA AMP 10
292 2DQU CPD 10.0313
293 6CDO ALA VAL GLY ILE GLY ALA VAL PHE 10.0313
294 3G08 FEE 10.101
295 3RUG DB6 10.101
296 1MHC FME TYR PHE ILE ASN ILE LEU THR LEU 10.101
297 5FKP 6UL 10.101
298 2QE0 NAP 10.1053
299 4TW7 37K 10.1562
300 6GWR FEW 10.1587
301 1QIN GIP 10.3825
302 1QD1 FON 10.4615
303 6EWZ APC 10.5485
304 2P1O IHP 10.625
305 2P1O NLA 10.625
306 2P1M IHP 10.625
307 4HWT 1B2 10.6583
308 3QRC SCR 10.828
309 5H2U 1N1 10.8614
310 4PXL NAD 10.9718
311 5T2Y 753 11.1111
312 1V3S ATP 11.2069
313 3L9R L9Q 11.2245
314 3L9R L9R 11.2245
315 4F7E 0SH 11.2245
316 3A5Z KAA 11.2805
317 4WN5 MVC 11.3043
318 4ASE AV9 11.3314
319 3LF0 ATP 11.4035
320 4XIZ LPP 11.4286
321 4OE4 NAD 11.5987
322 4RT1 C2E 11.6071
323 1F5F DHT 11.7073
324 1UWZ THU 11.7647
325 3L8W XAN 11.8243
326 5IXG OTP 11.8343
327 1Y60 H4M 11.8343
328 2Y6O 1N1 12.0275
329 3T50 FMN 12.5
330 1PZO CBT 12.5475
331 1Y7P RIP 12.5561
332 3TTZ 07N 12.6263
333 3ACL 3F1 12.8378
334 5UR1 YY9 12.8617
335 5FLJ QUE 12.9032
336 1NFS DED 13.1148
337 3N0Y APC 13.4078
338 3SXS PP2 13.4328
339 1N07 FMN 13.4969
340 4H2V AMP 13.6364
341 2Z77 HE7 13.6691
342 3BJK CIT 13.7255
343 5VFC 9BA 13.8264
344 4IEN COA 14.1104
345 5TVF CGQ 14.1176
346 2WLG SOP 14.4186
347 5N2D 8J8 14.5833
348 1O94 AMP 14.6875
349 3DZ6 M8E 14.9254
350 1I7M CG 14.9254
351 1NB9 RBF 14.966
352 1NB9 ADP 14.966
353 3NCQ ATP 15.126
354 1NMK SFM 15.7576
355 5NIU 8YZ 16.4062
356 5N2F 8HW 16.9355
357 2YC5 6BC 17.1053
358 3RF4 FUN 17.2414
359 5KY9 GDP 17.5
360 4N70 2HX 18.1818
361 2OJW ADP 18.75
362 2B9W FAD 18.8088
363 5VM0 9EG 19.5312
364 4LOO SB4 20.6897
365 1LFO OLA 21.0938
366 4X6F 3XU 21.9048
367 3AJH BL3 22.1774
368 4M1U MBG A2G 22.8571
369 4WO4 JLS 23
370 1OGA GLY ILE LEU GLY PHE VAL PHE THR LEU 23
371 5WL1 D3D 23.2323
372 5WL1 CUY 23.2323
373 3HUJ AGH 23.2323
374 4L4V 1VY 23.2323
375 5LXT GTP 23.3708
376 5EYP LOC 23.3708
377 5KY4 GDP 30
378 4CO3 ATP 32.1429
379 2UX9 FMN 46.3768
Pocket No.: 6; Query (leader) PDB : 1LSH; Ligand: PLD; Similar sites found with APoc: 76
This union binding pocket(no: 6) in the query (biounit: 1lsh.bio1) has 30 residues
No: Leader PDB Ligand Sequence Similarity
1 4L77 CNL 1.25628
2 1I1E DM2 2.19436
3 6GW4 CHO 2.28013
4 2C5S AMP 2.50784
5 3PUN FUC GAL NDG FUC 2.8481
6 4RQL SNE 2.94118
7 1OJK GLC BGC 3.1348
8 1OJJ GLC GAL 3.1348
9 6E1Q CFA 3.19328
10 3ZF8 GDP 3.27869
11 1ZNY GDP 3.38164
12 4CJN QNZ 3.44828
13 3ZGJ RMN 3.44828
14 5FPE 3TR 3.61757
15 2NZ2 CIR 3.76176
16 2EB5 OXL 4.11985
17 1QH5 GSH 4.23077
18 1H3F TYE 4.39815
19 2CYB TYR 4.64396
20 2IF8 ADP 4.6832
21 3JQ3 ADP 4.91803
22 4ZTD ALA GLY ALA GLY ALA 5.01567
23 3VKX T3 5.01567
24 1MFI FHC 5.26316
25 1NVM OXL 5.32915
26 1FHX 4IP 5.42636
27 4FE2 AIR 5.4902
28 2VFT SOR 5.64263
29 1YKD CMP 5.64263
30 5LXB 7A9 5.78512
31 5CHR 4NC 5.83942
32 5F7J ADE 5.9375
33 5N0L ILE 6.28931
34 3EZ2 ADP 6.53266
35 4URX HXY 6.58307
36 1OIJ AKG 6.64452
37 5LDQ NAP 6.77966
38 5FWJ MMK 6.89655
39 6BR9 PGV 6.96379
40 5EO8 TFU 7.07396
41 1VRP ADP 7.19697
42 2OVW CBI 7.21003
43 3T0W DIW 7.31707
44 4DVE BTN 7.57576
45 6C5F 7L9 7.69231
46 4U60 SIA GAL NGA 7.85714
47 3JU6 ANP 8.15047
48 1SZO CAX 8.94942
49 5A7Y SAH 8.97436
50 5EZU MYR 8.98876
51 2WOR 2AN 9
52 4YVN EBS 9.40439
53 5VL2 9EG 9.84848
54 5TV6 PML 10
55 5X7Q GLC GLC GLC GLC GLC 10.0313
56 5CLO NS8 10.1695
57 2PFC PLM 10.3825
58 3PNA CMP 10.3896
59 1C9K 5GP 10.5556
60 3RMK BML 10.8434
61 2XG5 EC2 11.0092
62 2XG5 EC5 11.0092
63 5VNF VAL THR SER VAL VAL 12.1019
64 1T0S BML 12.7907
65 5L83 ASP TRP GLU ILE VAL 14.2857
66 3DZ6 PUT 14.9254
67 2R09 4IP 14.9856
68 1P0Z FLC 16.0305
69 5HWV MBN 16.9231
70 6GMR F4K 17.5258
71 4KAX 4IP 19.5266
72 5XEG AKG 24.2424
73 1LNX URI 24.6914
74 5YRV 5AD 26.2774
75 4IAW LIZ 30.8511
76 2QL9 CIT 30.9278
Pocket No.: 7; Query (leader) PDB : 1LSH; Ligand: PLD; Similar sites found with APoc: 53
This union binding pocket(no: 7) in the query (biounit: 1lsh.bio1) has 17 residues
No: Leader PDB Ligand Sequence Similarity
1 4OYA 1VE 1.88088
2 1ODM ASV 2.1148
3 4YDQ ANP 2.8169
4 4YDQ HFG 2.8169
5 2Z81 PCJ 2.91439
6 5KD6 6C7 3.10263
7 1E1O LYS 3.1348
8 5JFL NAD 3.1348
9 4UMX NAP 3.44828
10 5LIA 6XN 3.44828
11 3LVW GSH 3.76176
12 4YWV SSN 3.76176
13 2BJK NAD 3.87597
14 5BVA FAD 4.07523
15 4OZJ ADP 4.1958
16 1ERB ETR 4.37158
17 4BG4 ADP 4.49438
18 2IMP NAI 4.5929
19 4NPL AKG 4.8
20 3ZXR P3S 5.01567
21 3ZXR IQ1 5.01567
22 5N5U 7N8 5.41401
23 6C6O ENG 5.64263
24 5GGN LEC 6.09756
25 3CM2 X23 6.15385
26 1UNB AKG 6.43087
27 4L3L 5FI 6.57895
28 2JLD AG1 6.58307
29 2BW7 ECS 7.76256
30 2BW7 APC 7.76256
31 2GJ5 VD3 9.25926
32 3KJQ B94 9.47368
33 6GW1 CHO 9.87261
34 1V0C ACO 9.90099
35 1V0C KNC 9.90099
36 1KJM ALA GLN PHE SER ALA SER ALA SER ARG 10
37 3QUZ QUV 10.101
38 1RZX ACE VAL LYS GLU SER LEU VAL 10.2041
39 4P7U 1PS 10.7143
40 5VKM GAL SIA 10.8025
41 1CS4 FOK 10.8491
42 1CS4 101 10.8491
43 2E56 MYR 11.1111
44 3VQ2 LP4 LP5 MYR DAO 11.9122
45 1QY1 PRZ 12.069
46 2OBD 2OB 12.8527
47 4LH0 GLV 13.1661
48 2YG2 FLC 13.3721
49 1I7M PUT 14.9254
50 5TPV TYD 18.3007
51 5XS3 VAL ARG SER ARG ARG CYS LEU ARG LEU 22.449
52 5C0C ARG GLN PHE GLY PRO ASP TRP ILE VAL ALA 23
53 5T70 THR SER ASN LEU GLN GLU GLN ILE GLY TRP 23.2323
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