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Receptor
PDB id Resolution Class Description Source Keywords
1LYX 1.9 Å EC: 5.3.1.1 PLASMODIUM FALCIPARUM TRIOSEPHOSPHATE ISOMERASE (PFTIM)- PHOSPHOGLYCOLATE COMPLEX PLASMODIUM FALCIPARUM TIM BARRELS BETA-ALPHA BARRELS ISOMERASE
Ref.: STRUCTURE OF THE PLASMODIUM FALCIPARUM TRIOSEPHOSPH ISOMERASE-PHOSPHOGLYCOLATE COMPLEX IN TWO CRYSTAL F CHARACTERIZATION OF CATALYTIC LOOP OPEN AND CLOSED CONFORMATIONS IN THE LIGAND-BOUND STATE BIOCHEMISTRY V. 41 13178 2002
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
PGA A:401;
Valid;
none;
Ki = 0.029 mM
156.031 C2 H5 O6 P C(C(=...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1LYX 1.9 Å EC: 5.3.1.1 PLASMODIUM FALCIPARUM TRIOSEPHOSPHATE ISOMERASE (PFTIM)- PHOSPHOGLYCOLATE COMPLEX PLASMODIUM FALCIPARUM TIM BARRELS BETA-ALPHA BARRELS ISOMERASE
Ref.: STRUCTURE OF THE PLASMODIUM FALCIPARUM TRIOSEPHOSPH ISOMERASE-PHOSPHOGLYCOLATE COMPLEX IN TWO CRYSTAL F CHARACTERIZATION OF CATALYTIC LOOP OPEN AND CLOSED CONFORMATIONS IN THE LIGAND-BOUND STATE BIOCHEMISTRY V. 41 13178 2002
Members (9)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 14 families.
1 1LYX Ki = 0.029 mM PGA C2 H5 O6 P C(C(=O)O)O....
2 1O5X - 3PY C3 H4 O4 C(C(=O)C(=....
3 2VFH - 3PG C3 H7 O7 P C([C@H](C(....
4 1M7O - 3PG C3 H7 O7 P C([C@H](C(....
5 2VFE - 3PG C3 H7 O7 P C([C@H](C(....
6 2VFI Ki = 1.9 mM 3PG C3 H7 O7 P C([C@H](C(....
7 1M7P - G3H C3 H7 O6 P C([C@H](C=....
8 3PVF - PGA C2 H5 O6 P C(C(=O)O)O....
9 2VFG - 3PG C3 H7 O7 P C([C@H](C(....
70% Homology Family (9)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 10 families.
1 1LYX Ki = 0.029 mM PGA C2 H5 O6 P C(C(=O)O)O....
2 1O5X - 3PY C3 H4 O4 C(C(=O)C(=....
3 2VFH - 3PG C3 H7 O7 P C([C@H](C(....
4 1M7O - 3PG C3 H7 O7 P C([C@H](C(....
5 2VFE - 3PG C3 H7 O7 P C([C@H](C(....
6 2VFI Ki = 1.9 mM 3PG C3 H7 O7 P C([C@H](C(....
7 1M7P - G3H C3 H7 O6 P C([C@H](C=....
8 3PVF - PGA C2 H5 O6 P C(C(=O)O)O....
9 2VFG - 3PG C3 H7 O7 P C([C@H](C(....
50% Homology Family (63)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 1IIH Ki = 1.3 mM 3PG C3 H7 O7 P C([C@H](C(....
2 2X1T - RES C4 H10 N O8 P C([C@H]([C....
3 5I3K Ki = 12 uM PGA C2 H5 O6 P C(C(=O)O)O....
4 2VEL - PGA C2 H5 O6 P C(C(=O)O)O....
5 5I3I Ki = 2.6 mM PGA C2 H5 O6 P C(C(=O)O)O....
6 2V2C Ki = 0.39 mM PGA C2 H5 O6 P C(C(=O)O)O....
7 2VEN - CIT C6 H8 O7 C(C(=O)O)C....
8 5I3H Ki = 120 uM PGA C2 H5 O6 P C(C(=O)O)O....
9 2X1S - X1S C3 H6 O5 S C(CS(=O)(=....
10 1KV5 Ki = 60 uM PGA C2 H5 O6 P C(C(=O)O)O....
11 4TIM Ki = 6.9 mM 2PG C3 H7 O7 P C([C@H](C(....
12 1TTJ - PGH C2 H6 N O6 P C(C(=O)NO)....
13 6TIM Ki = 0.61 mM G3P C3 H9 O6 P C([C@H](CO....
14 1TRD Ki = 4 uM PGH C2 H6 N O6 P C(C(=O)NO)....
15 2VEK - CIT C6 H8 O7 C(C(=O)O)C....
16 2V2H Ki = 0.17 mM PGA C2 H5 O6 P C(C(=O)O)O....
17 2J27 Ki = 0.3 mM PGA C2 H5 O6 P C(C(=O)O)O....
18 4PC8 - GOA C2 H4 O3 C(C(=O)O)O
19 2X1R - X1R C6 H12 O4 S CCCS(=O)(=....
20 2X2G - 3PG C3 H7 O7 P C([C@H](C(....
21 1TTI - PGA C2 H5 O6 P C(C(=O)O)O....
22 1NF0 - 13P C3 H7 O6 P C(C(=O)COP....
23 7TIM - PGH C2 H6 N O6 P C(C(=O)NO)....
24 2YPI Ki = 15 uM PGA C2 H5 O6 P C(C(=O)O)O....
25 1NEY - 13P C3 H7 O6 P C(C(=O)COP....
26 2BTM - PGA C2 H5 O6 P C(C(=O)O)O....
27 5EYW - PGA C2 H5 O6 P C(C(=O)O)O....
28 4YMZ - 13P C3 H7 O6 P C(C(=O)COP....
29 3UWV - 2PG C3 H7 O7 P C([C@H](C(....
30 3UWW - 3PG C3 H7 O7 P C([C@H](C(....
31 3UWZ - G2H C3 H9 O6 P C(C(CO)OP(....
32 3M9Y - CIT C6 H8 O7 C(C(=O)O)C....
33 3UWU - G3P C3 H9 O6 P C([C@H](CO....
34 1LYX Ki = 0.029 mM PGA C2 H5 O6 P C(C(=O)O)O....
35 1O5X - 3PY C3 H4 O4 C(C(=O)C(=....
36 2VFH - 3PG C3 H7 O7 P C([C@H](C(....
37 1M7O - 3PG C3 H7 O7 P C([C@H](C(....
38 2VFE - 3PG C3 H7 O7 P C([C@H](C(....
39 2VFI Ki = 1.9 mM 3PG C3 H7 O7 P C([C@H](C(....
40 1M7P - G3H C3 H7 O6 P C([C@H](C=....
41 3PVF - PGA C2 H5 O6 P C(C(=O)O)O....
42 2VFG - 3PG C3 H7 O7 P C([C@H](C(....
43 3TAO Kd = 7.28 uM PGH C2 H6 N O6 P C(C(=O)NO)....
44 1SUX - BTS C10 H11 N O3 S3 c1ccc2c(c1....
45 1TPW Ki = 0.5 mM PGH C2 H6 N O6 P C(C(=O)NO)....
46 1SW3 - PGA C2 H5 O6 P C(C(=O)O)O....
47 1TPB - PGH C2 H6 N O6 P C(C(=O)NO)....
48 1SW0 - PGA C2 H5 O6 P C(C(=O)O)O....
49 1TPH - PGH C2 H6 N O6 P C(C(=O)NO)....
50 1TPU - PGH C2 H6 N O6 P C(C(=O)NO)....
51 1TPV - PGH C2 H6 N O6 P C(C(=O)NO)....
52 1SW7 - PGA C2 H5 O6 P C(C(=O)O)O....
53 1TPC - PGH C2 H6 N O6 P C(C(=O)NO)....
54 2VXN - PGA C2 H5 O6 P C(C(=O)O)O....
55 2Y62 - G3P C3 H9 O6 P C([C@H](CO....
56 1AMK Ki = 0.05 mM PGA C2 H5 O6 P C(C(=O)O)O....
57 2Y61 - G3P C3 H9 O6 P C([C@H](CO....
58 1QDS Ki = 0.048 mM PGA C2 H5 O6 P C(C(=O)O)O....
59 1N55 - PGA C2 H5 O6 P C(C(=O)O)O....
60 1IF2 - 129 C3 H8 N O5 P C(CP(=O)(O....
61 6BVE - PGA C2 H5 O6 P C(C(=O)O)O....
62 4BI6 Kd = 113.3 uM PGA C2 H5 O6 P C(C(=O)O)O....
63 4BI7 Kd = 26.4 uM PGA C2 H5 O6 P C(C(=O)O)O....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: PGA; Similar ligands found: 9
No: Ligand ECFP6 Tc MDL keys Tc
1 PGA 1 1
2 HPV 0.555556 0.903226
3 13P 0.5 0.818182
4 PGH 0.482759 0.651163
5 3PG 0.433333 0.90625
6 3PP 0.423077 0.866667
7 PAE 0.416667 0.806452
8 EFS 0.416667 0.741935
9 SEP 0.40625 0.710526
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1LYX; Ligand: PGA; Similar sites found with APoc: 389
This union binding pocket(no: 1) in the query (biounit: 1lyx.bio1) has 19 residues
No: Leader PDB Ligand Sequence Similarity
1 3HYK A3P None
2 1FTH A3P None
3 2CBO TH2 None
4 5K9B FMN None
5 1QPR PPC None
6 4I9A NCN 0.806452
7 1U7Z PMT 1.32743
8 6GNO XDI 1.48148
9 4N02 FNR 1.6129
10 4CTA ATP 1.6129
11 1GPM AMP 1.6129
12 2R14 FMN 2.01613
13 2R14 TXD 2.01613
14 1TLL FMN 2.01613
15 4JIQ FMN 2.01613
16 4JIQ 1L5 2.01613
17 1SFF IK2 2.01613
18 5EZ7 FAD 2.01613
19 4C01 QY9 2.01613
20 1LVL FAD 2.01613
21 4Y30 49L 2.01613
22 4Y30 SAH 2.01613
23 4FMS BDP 2.01613
24 6CI9 NAP 2.01613
25 1MZV AMP 2.12766
26 3CTL S6P 2.1645
27 3ESS 18N 2.17391
28 1Q9I FAD 2.41935
29 1Q9I TEO 2.41935
30 3C3N FMN 2.41935
31 3MI2 PFU 2.41935
32 5KJW 53C 2.41935
33 1UUO FMN 2.41935
34 1UUO ORO 2.41935
35 1UUO BRF 2.41935
36 2CUN 3PG 2.41935
37 4RF7 ARG 2.41935
38 6DVH FMN 2.41935
39 1EK6 NAI 2.41935
40 1EK6 UPG 2.41935
41 3VKC FPQ 2.41935
42 1PS9 FMN 2.41935
43 5G48 1FL 2.41935
44 1Q0H FOM 2.41935
45 1Q0H NDP 2.41935
46 5EYY MDM 2.44898
47 3NC9 TR3 2.55591
48 1QKQ MAN 2.8169
49 3BW2 FMN 2.82258
50 4Q4K FMN 2.82258
51 2Z6J FMN 2.82258
52 3MJY IJZ 2.82258
53 2Z6I FMN 2.82258
54 1PVN MZP 2.82258
55 1ME8 RVP 2.82258
56 3N9R TD3 2.82258
57 3MJY FMN 2.82258
58 2FJK 13P 2.82258
59 6BFG FMN 2.82258
60 6F5W KG1 2.82258
61 1OYB FMN 2.82258
62 1OYB HBA 2.82258
63 3PE2 E1B 2.82258
64 3C56 PH4 2.82258
65 4TMC FMN 2.82258
66 5X8G S0N 2.82258
67 5WS9 AMP 2.82258
68 4TMC HBA 2.82258
69 1M5W DXP 2.88066
70 5ZZ6 NAD 2.88462
71 4JEM C5P 2.94118
72 2FXV 5GP 3.09278
73 3G6N MET ALA SER 3.14136
74 2Q3O FMN 3.22581
75 1GTE IUR 3.22581
76 1GTE FMN 3.22581
77 1P4C FMN 3.22581
78 5J60 FAD 3.22581
79 1ZGS XMM 3.22581
80 1JCM 137 3.22581
81 2OEM 1AE 3.22581
82 1Z45 NAD 3.22581
83 1UDB UFG 3.22581
84 1UDB NAD 3.22581
85 2DPM SAM 3.22581
86 5JIC N7E 3.22581
87 5JIC ADP 3.22581
88 2GKS ADP 3.22581
89 4OUJ LBT 3.22581
90 2WTX UDP 3.22581
91 6GVZ CHO 3.22581
92 2ZE3 AKG 3.22581
93 5JDA SIN 3.22581
94 2Q3R FMN 3.22581
95 3OFK SAH 3.24074
96 1F5V FMN 3.33333
97 1DBT U5P 3.34728
98 3OVR 5SP 3.50877
99 5YRL GLC GLC 3.52113
100 5YRM BGC GLC 3.52113
101 5YRF GLC GLC 3.52113
102 5YRI GLC GLC 3.52113
103 5YRG BGC GLC 3.52113
104 5YRJ BGC GLC 3.52113
105 5H86 BCO 3.57143
106 5XFV FMN 3.62903
107 6BKA FMN 3.62903
108 3KRU FMN 3.62903
109 2C6Q NDP 3.62903
110 2C6Q IMP 3.62903
111 1NJJ ORX 3.62903
112 4V15 PLP 3.62903
113 3UCL NAP 3.62903
114 3UCL FAD 3.62903
115 3UCL CYH 3.62903
116 4QYS PLR 3.62903
117 2Q1S NAI 3.62903
118 5Y1G AKB 3.62903
119 1L7E NAI 3.62903
120 4RJK TPP 3.62903
121 4RJK TDL 3.62903
122 2RGH FAD 3.62903
123 2FLI DX5 3.63636
124 1XXR MAN 3.72671
125 5TQZ GLC 4
126 3HF3 FMN 4.01146
127 2NVA PL2 4.03226
128 1EP2 ORO 4.03226
129 1EP2 FMN 4.03226
130 1F76 FMN 4.03226
131 5FA6 FAD 4.03226
132 5FA6 FMN 4.03226
133 5FA6 NAP 4.03226
134 1NHX PEP 4.03226
135 1NHX FTB 4.03226
136 4NZ6 DGL 4.03226
137 2PLK P3D 4.03226
138 6EK3 OUL 4.0724
139 1GXS BEZ 4.07407
140 4HEQ FMN 4.10959
141 1KBJ FMN 4.43548
142 4HKP TKW 4.43548
143 4CW5 FMN 4.43548
144 4HKP 16B 4.43548
145 4ZNO SUC 4.43548
146 5C9P FUC 4.43548
147 1ZFJ IMP 4.43548
148 3WQD PLP 999 4.43548
149 6AR9 3L4 4.43548
150 5W4W 9WG 4.43548
151 1OZH HE3 4.43548
152 4M00 SUC 4.43548
153 4JEJ 1GP 4.5082
154 1G27 BB1 4.7619
155 1RL4 BRR 4.78723
156 4EWN 0VR 4.83871
157 1CX9 NHP 4.83871
158 2RDT 2RD 4.83871
159 5J5R IMP 4.83871
160 5J5R 6G1 4.83871
161 2RDT FMN 4.83871
162 3OIX FMN 4.83871
163 1Z44 FMN 4.83871
164 1Z48 FMN 4.83871
165 3LZW FAD 4.83871
166 3LZW NAP 4.83871
167 3KDN CAP 4.83871
168 2IHU TP9 4.83871
169 1UPA TPP 4.83871
170 1Z42 FMN 4.83871
171 6GAS FAD 4.83871
172 1DJN FMN 4.83871
173 1Z41 FMN 4.83871
174 2IHT TPP 4.83871
175 5OCS FMN 4.83871
176 1LOB MMA 4.97238
177 2ZFZ ARG 5.06329
178 2GN3 MMA 5.15873
179 2PHX MAN MAN 5.15873
180 2GN3 MAN 5.15873
181 2GMM MAN MAN 5.15873
182 1Q8Q MAN MMA 5.15873
183 2GNB MAN 5.15873
184 1Q8P MAN MMA 5.15873
185 2PHU MAN MAN 5.15873
186 1Q8O MAN MMA 5.15873
187 2GND MAN 5.15873
188 1Q8S MAN MMA 5.15873
189 2GNM MAN 5.15873
190 1Q8V MAN MAN 5.15873
191 2PHT MAN MAN MAN 5.15873
192 2PHF MAN MAN BMA MAN 5.15873
193 2PHR MAN MAN BMA MAN 5.15873
194 2PHT MAN MAN MAN BMA MAN 5.15873
195 3KYF 5GP 5GP 5.19481
196 1X1Z BMP 5.24194
197 4ORM 2V6 5.24194
198 4ORM FMN 5.24194
199 4ORM ORO 5.24194
200 6AMI TRP 5.24194
201 1YBH P22 5.24194
202 5WKC AUJ 5.24194
203 5WKC TP9 5.24194
204 1ZBQ NAD 5.24194
205 1T9D P22 5.24194
206 4XDA ADP 5.24194
207 2NXW TPP 5.24194
208 4E13 NAD 5.24194
209 5AHN IMP 5.31697
210 2JBH 5GP 5.33333
211 5DYO FLU 5.50459
212 5FA8 SAM 5.59006
213 1GVF PGH 5.64516
214 2BLE 5GP 5.64516
215 2QCD U5P 5.64516
216 3ITJ FAD 5.64516
217 2AQJ FAD 5.64516
218 2AQJ TRP 5.64516
219 3IAE D7K 5.64516
220 3ITJ CIT 5.64516
221 1TV5 FMN 5.64516
222 2X7J TPP 5.64516
223 3GAY P6T 5.64516
224 3EYA TDP 5.64516
225 4AF0 IMP 5.64516
226 3VET ADP 5.64516
227 3VET CP 5.64516
228 2UZ1 TPP 5.64516
229 6AYU MLI 5.64516
230 2NV2 GLN 5.64516
231 1LOR BMP 5.70175
232 4D57 ARG AMP 5.75916
233 1VKF CIT 5.85106
234 4KXL 6C6 5.92105
235 2BQP GLC 5.98291
236 5WHU SIA 6.04027
237 1VBO MAN MAN MAN 6.04027
238 1QO8 FAD 6.04839
239 4WZH FMN 6.04839
240 5LKC FUC GLA A2G 6.04839
241 3OQJ 3CX 6.04839
242 5BSR AMP 6.04839
243 4UZI IMD 6.04839
244 1B1C FMN 6.07735
245 1EIX BMQ 6.12245
246 1OVD ORO 6.45161
247 4Z87 5GP 6.45161
248 4Z0G 5GP 6.45161
249 1OVD FMN 6.45161
250 2H8Z 8CM 6.45161
251 2H8Z FMN 6.45161
252 4A3U FMN 6.45161
253 1N62 FAD 6.45161
254 5VJE GOS 6.45161
255 6ARJ SAH 6.45161
256 6ARJ BW4 6.45161
257 5TWB FAD 6.45161
258 3QTP 2PG 6.45161
259 5AHM IMP 6.5
260 4JLS 3ZE 6.57895
261 6FOG OXL 6.69643
262 5XDT ZI7 6.81818
263 3B0P FMN 6.85484
264 1ICP FMN 6.85484
265 5GJO PLP 6.85484
266 1VDC FAD 6.85484
267 1ZK7 FAD 6.85484
268 4XP7 FNR 6.85484
269 4IXH IMP 6.85484
270 5O0J GLC 6.85484
271 5HWV MBN 6.92308
272 2XRH NIO 7
273 1AL8 DHP 7.25806
274 5K0A FAD 7.25806
275 4J56 FAD 7.25806
276 2XVE FAD 7.25806
277 2XVF FAD 7.25806
278 5WXU FLC 7.25806
279 3CIP ATP 7.25806
280 1AL8 FMN 7.25806
281 5TCI MLI 7.66129
282 4QNW FMN 7.66129
283 2GOU FMN 7.66129
284 2GAG FAD 7.66129
285 2HW1 ANP 7.66129
286 2GAG FOA 7.66129
287 1OX5 1PR 8.06452
288 2ZRU FMN 8.06452
289 2OO0 PLP 8.06452
290 5BOE PEP 8.06452
291 2Q8Z NUP 8.18713
292 5A5W GUO 8.46774
293 2GJN NIS 8.46774
294 2GJN FMN 8.46774
295 1VYP FMN 8.46774
296 1VYP TNF 8.46774
297 1TUF AZ1 8.46774
298 1UZD CAP 8.46774
299 1KNR FAD 8.46774
300 2VBF TPP 8.46774
301 5EXK MET 8.46774
302 5WM2 SAL 8.46774
303 1BZY IMU 8.75576
304 1OFD FMN 8.87097
305 1OFD AKG 8.87097
306 1DQX BMP 8.87097
307 1HFE CYS 8.87097
308 4MRT COA 9.05172
309 6GAQ FMN 9.09091
310 1D1Q 4NP 9.31677
311 4NAE 1GP 9.33333
312 1S17 GNR 9.44444
313 3QH2 3NM 9.50226
314 1T3Q FAD 9.52381
315 1T3Q MCN 9.52381
316 3E5P PPI 9.67742
317 1T3D CYS 9.67742
318 3HRD FAD 9.67742
319 2RGO FAD 9.67742
320 5EB4 FAD 9.67742
321 2OKL BB2 9.72973
322 2GUD MAN 9.83607
323 2GUC MAN 9.83607
324 2NU5 NAG 9.83607
325 2HYQ MAN MAN 9.83607
326 2HYR BGC GLC 9.83607
327 2NUO BGC 9.83607
328 4UTU LRY 10.0437
329 4UTW RFW 10.0437
330 3QMN A3P 10.0775
331 3QMN COA 10.0775
332 3W9Z FMN 10.0806
333 2WET FAD 10.0806
334 4D62 SIA 10.1604
335 1L1Q 9DA 10.2151
336 4H2D FMN 10.303
337 1XTT U5P 10.6481
338 4MDB RLT 10.6667
339 2V63 CAP 10.7143
340 2VDH CAP 10.7143
341 2V6A CAP 10.7143
342 2V67 CAP 10.7143
343 1IR2 CAP 10.7143
344 2V68 CAP 10.7143
345 3EXS 5RP 10.8597
346 1HGX 5GP 10.929
347 5Y6Q FAD 11.1111
348 3ATY FMN 11.2903
349 1GQ2 NAP 11.2903
350 1UZH CAP 11.4754
351 3CQD ATP 11.6935
352 1LBF 137 11.7409
353 1UJP CIT 11.8081
354 1TB3 FMN 12.0968
355 1CZR FMN 12.426
356 2HSA FMN 12.5
357 4UP3 FAD 12.9032
358 3AXK NDP 12.9032
359 2VAR ANP 12.9032
360 1WDD CAP 12.9032
361 2VAR AMP 12.9032
362 1C3M MAN MAN 12.9252
363 4ZOH MCN 13.0952
364 5GVH FMN 13.3065
365 3F6R FMN 13.5135
366 5EXE 5SR 13.7097
367 1QPB TPP 14.1129
368 1QPB PYM 14.1129
369 4JNE ATP 14.1129
370 1LES GLC FRU 15.3846
371 4A22 TD4 15.407
372 1Q6O LG6 15.7407
373 2Y88 2ER 15.9836
374 1OFS SUC 16.6667
375 2C42 PYR 16.9355
376 2C42 TPP 16.9355
377 4IGH 1EA 17.3387
378 4IGH ORO 17.3387
379 4IGH FMN 17.3387
380 2NLI FMN 17.7419
381 2NLI LAC 17.7419
382 1D4D FAD 18.1452
383 1KBI FMN 18.5484
384 1KBI PYR 18.5484
385 2F6U CIT 20.0855
386 5N9Z CAP 22.3022
387 5OYA CAP 22.3022
388 1RBL CAP 23.8532
389 1IR1 CAP 32.5203
Pocket No.: 2; Query (leader) PDB : 1LYX; Ligand: PGA; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 1lyx.bio1) has 19 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 3; Query (leader) PDB : 1LYX; Ligand: PGA; Similar sites found with APoc: 15
This union binding pocket(no: 3) in the query (biounit: 1lyx.bio2) has 19 residues
No: Leader PDB Ligand Sequence Similarity
1 2Q7V FAD 2.01613
2 3FPF MTA 2.41935
3 3FPF TNA 2.41935
4 3A4V PYR 2.82258
5 3A4V NAD 2.82258
6 3EHH ADP 3.21101
7 3DOO SKM 3.22581
8 3LN0 52B 3.62903
9 1BKJ FMN 4.16667
10 2GV8 FAD 7.66129
11 1CZA G6P 7.66129
12 5WM2 AMP 8.46774
13 1RM0 NAI 10.0806
14 4WS6 WBU 10.5042
15 3KAP FMN 10.8844
Pocket No.: 4; Query (leader) PDB : 1LYX; Ligand: PGA; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 1lyx.bio2) has 19 residues
No: Leader PDB Ligand Sequence Similarity
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