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Receptor
PDB id Resolution Class Description Source Keywords
1M6Y 1.9 Å EC: 2.1.1.- CRYSTAL STRUCTURE ANALYSIS OF TM0872, A PUTATIVE SAM-DEPENDE METHYLTRANSFERASE, COMPLEXED WITH SAH THERMOTOGA MARITIMA SAM-DEPENDENT METHYLTRANSFERASE FOLD PROTEIN-COFACTOR PRODUCOMPLEX STRUCTURAL GENOMICS PSI PROTEIN STRUCTURE INITIAMIDWEST CENTER FOR STRUCTURAL GENOMICS MCSG TRANSFERASE
Ref.: CRYSTAL COMPLEXES OF A PREDICTED S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE RE TYPICAL ADOMET BINDING DOMAIN AND A SUBSTRATE RECOG DOMAIN PROTEIN SCI. V. 12 1432 2003
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
SAH A:401;
B:402;
 Valid;
Valid;
 none;
none;
 submit data
384.411 C14 H20 N6 O5 S c1nc(...
SO4 A:500;
B:501;
 Invalid;
Invalid;
 none;
none;
 submit data
96.063 O4 S [O-]S...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1N2X 1.9 Å EC: 2.1.1.- CRYSTAL STRUCTURE ANALYSIS OF TM0872, A PUTATIVE SAM- DEPENDENT METHYLTRANSFERASE, COMPLEXED WITH SAM THERMOTOGA MARITIMA SAM-DEPENDENT METHYLTRANSFERASE FOLD PROTEIN-SAM METHYL DONOR COMPLEX STRUCTURAL GENOMICS PSI PROTEIN STRUCTURE INITIATIVE MIDWEST CENTER FOR STRUCTURAL GENOMICS MCSG
Ref.: CRYSTAL COMPLEXES OF A PREDICTED S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE REVEAL A TYPICAL ADOMET BINDING DOMAIN AND A SUBSTRATE RECOGNITION DOMAIN PROTEIN SCI. V. 12 1432 2003
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 60 families.
1 1M6Y - SAH C14 H20 N6 O5 S c1nc(c2c(n....
2 1N2X - SAM C15 H22 N6 O5 S C[S@@+](CC....
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 54 families.
1 1M6Y - SAH C14 H20 N6 O5 S c1nc(c2c(n....
2 1N2X - SAM C15 H22 N6 O5 S C[S@@+](CC....
50% Homology Family (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 47 families.
1 3TKA - SAM C15 H22 N6 O5 S C[S@@+](CC....
2 1M6Y - SAH C14 H20 N6 O5 S c1nc(c2c(n....
3 1N2X - SAM C15 H22 N6 O5 S C[S@@+](CC....
4 1WG8 - SAM C15 H22 N6 O5 S C[S@@+](CC....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: SAH; Similar ligands found: 211
No: Ligand ECFP6 Tc MDL keys Tc
1 SAH 1 1
2 5X8 0.759494 0.969697
3 A7D 0.734177 0.926471
4 TT8 0.709302 0.970588
5 DSH 0.692308 0.914286
6 SXZ 0.692308 0.916667
7 DTA 0.666667 0.857143
8 3DH 0.662338 0.869565
9 S8M 0.655556 0.901408
10 SFG 0.635294 0.954545
11 SA8 0.62069 0.915493
12 EEM 0.617977 0.890411
13 MTA 0.615385 0.869565
14 SAI 0.613636 0.955882
15 S7M 0.586957 0.916667
16 36A 0.586538 0.90411
17 K15 0.583333 0.878378
18 ADN 0.573333 0.84058
19 RAB 0.573333 0.84058
20 XYA 0.573333 0.84058
21 62X 0.572917 0.855263
22 5CD 0.571429 0.852941
23 0UM 0.5625 0.876712
24 5N5 0.558442 0.84058
25 A4D 0.551282 0.867647
26 SAM 0.537634 0.916667
27 SMM 0.536842 0.88
28 SSA 0.536842 0.712644
29 KB1 0.534653 0.902778
30 A5D 0.532609 0.857143
31 SIB 0.53125 0.928571
32 EP4 0.530864 0.819444
33 DSZ 0.530612 0.732558
34 GSU 0.53 0.752941
35 A 0.529412 0.763158
36 LMS 0.529412 0.694118
37 AMP 0.529412 0.763158
38 5CA 0.525773 0.712644
39 ME8 0.524752 0.8125
40 M2T 0.52439 0.821918
41 6RE 0.523256 0.824324
42 GJV 0.522727 0.813333
43 AAT 0.515789 0.863014
44 LSS 0.515152 0.696629
45 KAA 0.514852 0.727273
46 J7C 0.511364 0.835616
47 A5A 0.510417 0.697674
48 SON 0.505495 0.805195
49 SRP 0.505155 0.805195
50 F0P 0.504505 0.915493
51 54H 0.5 0.681818
52 VMS 0.5 0.681818
53 ADX 0.5 0.694118
54 CA0 0.5 0.769231
55 AMO 0.5 0.805195
56 5AL 0.5 0.779221
57 KH3 0.5 0.866667
58 NVA LMS 0.49505 0.707865
59 AHX 0.49505 0.753086
60 TSB 0.494949 0.689655
61 53H 0.494949 0.674157
62 G5A 0.494737 0.712644
63 ABM 0.494382 0.74359
64 A2D 0.494382 0.74359
65 ZAS 0.494253 0.808219
66 A6D 0.490196 0.759494
67 8QN 0.49 0.779221
68 GEK 0.49 0.956522
69 GAP 0.489583 0.769231
70 AN2 0.48913 0.734177
71 A3S 0.48913 0.884058
72 S4M 0.488889 0.831169
73 SRA 0.488636 0.746835
74 LAD 0.485437 0.810127
75 52H 0.484848 0.674157
76 A12 0.483516 0.759494
77 BA3 0.483516 0.74359
78 AP2 0.483516 0.759494
79 NEC 0.483146 0.788732
80 AOC 0.483146 0.842857
81 Y3J 0.481481 0.768116
82 VRT 0.479167 0.861111
83 50T 0.478723 0.734177
84 B4P 0.478261 0.74359
85 ADP 0.478261 0.74359
86 5AS 0.478261 0.655556
87 AP5 0.478261 0.74359
88 A3N 0.477778 0.830986
89 YSA 0.476636 0.712644
90 XAH 0.476636 0.768293
91 0XU 0.473684 0.897059
92 AT4 0.473118 0.7375
93 WAQ 0.471154 0.807692
94 NSS 0.470588 0.712644
95 5AD 0.468354 0.791045
96 AU1 0.468085 0.725
97 M33 0.468085 0.734177
98 MAO 0.467391 0.797468
99 TXA 0.466667 0.759494
100 NB8 0.466667 0.775
101 A3G 0.466667 0.871429
102 3AM 0.465909 0.727273
103 DAL AMP 0.465347 0.779221
104 8X1 0.465347 0.707865
105 A3T 0.463158 0.842857
106 ATP 0.463158 0.74359
107 HEJ 0.463158 0.74359
108 ACP 0.463158 0.746835
109 7D7 0.4625 0.785714
110 LEU LMS 0.461538 0.688889
111 9ZA 0.460784 0.740741
112 9ZD 0.460784 0.740741
113 5FA 0.458333 0.74359
114 AQP 0.458333 0.74359
115 AR6 0.458333 0.766234
116 APC 0.458333 0.759494
117 APR 0.458333 0.766234
118 PRX 0.458333 0.746835
119 F2R 0.457627 0.75
120 IOT 0.456897 0.761905
121 4AD 0.456311 0.794872
122 PAJ 0.456311 0.722892
123 WSA 0.45614 0.72093
124 YAP 0.453704 0.794872
125 8PZ 0.453704 0.712644
126 FA5 0.453704 0.805195
127 ADP PO3 0.453608 0.763158
128 ADV 0.453608 0.782051
129 NVA 2AD 0.453608 0.849315
130 SAP 0.453608 0.728395
131 AGS 0.453608 0.728395
132 RBY 0.453608 0.782051
133 AD9 0.453608 0.725
134 PTJ 0.45283 0.731707
135 MHZ 0.452632 0.797468
136 00A 0.451923 0.740741
137 A3P 0.451613 0.74026
138 YLP 0.451327 0.771084
139 7MD 0.45045 0.768293
140 ALF ADP 0.45 0.707317
141 ADP ALF 0.45 0.707317
142 2VA 0.447917 0.819444
143 OOB 0.446602 0.779221
144 ANP 0.444444 0.725
145 T99 0.444444 0.7375
146 ACQ 0.444444 0.746835
147 TAT 0.444444 0.7375
148 P5A 0.443396 0.719101
149 7D5 0.443182 0.708861
150 A1R 0.442308 0.7625
151 YLC 0.439655 0.790123
152 2AM 0.438202 0.717949
153 DLL 0.438095 0.779221
154 ARG AMP 0.4375 0.759036
155 A22 0.436893 0.734177
156 D3Y 0.436893 0.859155
157 ATF 0.435644 0.716049
158 MYR AMP 0.435185 0.746988
159 80F 0.434426 0.75
160 SO8 0.434343 0.808219
161 OAD 0.433962 0.769231
162 3UK 0.433962 0.769231
163 TAD 0.433628 0.765432
164 25A 0.432692 0.74359
165 6YZ 0.431373 0.746835
166 VO4 ADP 0.431373 0.734177
167 ADP VO4 0.431373 0.734177
168 9SN 0.431193 0.731707
169 TYM 0.431034 0.805195
170 B5V 0.429907 0.759494
171 PR8 0.429907 0.8
172 ADQ 0.428571 0.746835
173 YLB 0.42735 0.771084
174 9K8 0.425926 0.67033
175 1ZZ 0.425926 0.746988
176 FYA 0.425926 0.779221
177 3OD 0.425926 0.769231
178 PPS 0.425743 0.674419
179 MAP 0.423077 0.707317
180 A2P 0.421053 0.727273
181 4YB 0.421053 0.735632
182 9X8 0.420561 0.75
183 ADP BMA 0.420561 0.746835
184 TYR AMP 0.419643 0.794872
185 5SV 0.419048 0.731707
186 3NZ 0.416667 0.824324
187 YLA 0.416667 0.771084
188 8Q2 0.415254 0.688889
189 A3R 0.415094 0.7625
190 B5Y 0.414414 0.75
191 B5M 0.414414 0.75
192 48N 0.413793 0.753086
193 LPA AMP 0.413793 0.768293
194 AYB 0.413223 0.761905
195 ACK 0.413043 0.710526
196 QQY 0.413043 0.696203
197 BIS 0.412844 0.719512
198 JB6 0.412844 0.7625
199 PAP 0.41 0.730769
200 DQV 0.408696 0.75641
201 OVE 0.408602 0.7125
202 AMP DBH 0.40708 0.746835
203 4UV 0.40708 0.75
204 3AD 0.406977 0.852941
205 AF3 ADP 3PG 0.40678 0.743902
206 OMR 0.40678 0.738095
207 LAQ 0.405172 0.768293
208 A A 0.40367 0.74359
209 7C5 0.403509 0.789474
210 7MC 0.403361 0.75
211 4UU 0.4 0.75
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1N2X; Ligand: SAM; Similar sites found with APoc: 702
This union binding pocket(no: 1) in the query (biounit: 1n2x.bio2) has 25 residues
No: Leader PDB Ligand Sequence Similarity
1 5NNS AKR None
2 6MJ7 ARG None
3 2BOS GLA GAL GLC NBU None
4 2BOS GLA GAL GLC None
5 1BW9 NAD None
6 1PTR PRB None
7 3ZV6 NAD None
8 3ZV6 4HB None
9 1TDF FAD 1.3289
10 3X0V FAD 1.3289
11 1TDF NAP 1.3289
12 1OKE BOG 1.3289
13 3GD8 GOL 1.34529
14 4RDH AMP 1.38889
15 4RDI ATP 1.38889
16 4X9M FAD 1.43541
17 4D79 ATP 1.44928
18 3VSE SAH 1.66113
19 2EJU SAH 1.66113
20 2CDU ADP 1.66113
21 2Q7V FAD 1.66113
22 4HXY NDP 1.66113
23 2CDU FAD 1.66113
24 5BVA FAD 1.66113
25 4YAC NAI 1.6835
26 1JJ7 ADP 1.92308
27 5ZI9 FLC 1.92308
28 1GEG NAD 1.95312
29 5FJN FAD 1.97368
30 5FJN BE2 1.97368
31 3PT9 SAH 1.99336
32 2YX1 SFG 1.99336
33 1BZL GCG 1.99336
34 1BZL FAD 1.99336
35 1MO9 KPC 1.99336
36 1MO9 FAD 1.99336
37 5T67 SAH 1.99336
38 5T67 JHZ 1.99336
39 1LVL NAD 1.99336
40 3CGD NAD 1.99336
41 3CGD FAD 1.99336
42 3CGD COA 1.99336
43 4C3Y FAD 1.99336
44 3IHG FAD 1.99336
45 4D7E FAD 1.99336
46 4C3Y ANB 1.99336
47 4MO2 FDA 1.99336
48 1LVL FAD 1.99336
49 4U8P UDP 1.99336
50 4MO2 FAD 1.99336
51 2NPX FAD 1.99336
52 2NPX NAD 1.99336
53 4U8P FDA 1.99336
54 3NUG NAD 2.02429
55 2AOT SAH 2.05479
56 1JQD SAH 2.05479
57 1JQD HSM 2.05479
58 4YMH SAH 2.08333
59 3MBI HSX 2.09059
60 4U60 SIA GAL BGC NGA GAL 2.14286
61 5KVA SAM 2.15827
62 5O42 9JW 2.18978
63 5O42 NAD 2.18978
64 5O42 BGC 2.18978
65 1GXU 2HP 2.1978
66 6AR9 3L4 2.20588
67 3RKR NAP 2.29008
68 3BGD SAH 2.30769
69 3BGD PM6 2.30769
70 4UCI SAM 2.32558
71 4LWP SAH 2.32558
72 4KRG SAH 2.32558
73 1GOJ ADP 2.32558
74 1COY FAD 2.32558
75 1CT9 GLN 2.32558
76 2C7G FAD 2.32558
77 4FWE FAD 2.32558
78 2C7G ODP 2.32558
79 4BV6 FAD 2.32558
80 4UCI ADN 2.32558
81 3QJ4 FAD 2.32558
82 1COY AND 2.32558
83 2VVG ADP 2.32558
84 1REO FAD 2.32558
85 3FPF TNA 2.34899
86 3FPF MTA 2.34899
87 3H8V ATP 2.39726
88 3GEG NAD 2.42915
89 2BD0 NAP 2.45902
90 1I9G SAM 2.5
91 3C3Y SAH 2.53165
92 1JG3 ADN 2.55319
93 1AE1 NAP 2.5641
94 4WXJ GLU 2.60223
95 3RFV 15L 2.62172
96 3RFV NAI 2.62172
97 2GDZ NAD 2.62172
98 6ARJ BW4 2.65781
99 4PNE SAH 2.65781
100 5FUB SAH 2.65781
101 6ARJ SAH 2.65781
102 5DWQ SFG 2.65781
103 1FEC FAD 2.65781
104 5DXA SFG 2.65781
105 5DX8 SFG 2.65781
106 5DX1 SFG 2.65781
107 1YQZ FAD 2.65781
108 5DX0 SFG 2.65781
109 3UCL FAD 2.65781
110 3UCL CYH 2.65781
111 3UCL NAP 2.65781
112 1YXM ADE 2.65781
113 1PN0 FAD 2.65781
114 1PN0 IPH 2.65781
115 5TUF FAD 2.65781
116 5TUF TDC 2.65781
117 2V6G NAP 2.65781
118 5ZYN FAD 2.65781
119 1PZG A3D 2.65781
120 1ZGS XMM 2.65781
121 2IVD FAD 2.65781
122 5F8F SFG 2.65781
123 3LRE ADP 2.65781
124 5JE8 NAD 2.65781
125 5G3U FDA 2.65781
126 5G3U ITW 2.65781
127 1NFQ NAI 2.69231
128 1Q0S SAH 2.7027
129 2DPM SAM 2.8169
130 1NJR XYL 2.8169
131 1C3V PDC 2.85714
132 1XKQ NDP 2.85714
133 5GWT SIN 2.8777
134 5GWT NAD 2.8777
135 4IF4 BEF 2.88462
136 6ECU SAH 2.99003
137 5MPT SAH 2.99003
138 6ECW SAH 2.99003
139 1PJS NAD 2.99003
140 3L9W AMP 2.99003
141 2DTX BMA 2.99003
142 3L9W GSH 2.99003
143 1UXG FUM 2.99003
144 1UXG NAD 2.99003
145 3A4V NAD 2.99003
146 3A4V PYR 2.99003
147 4RPL FAD 2.99003
148 4RPL 3UC 2.99003
149 3E1T FAD 2.99003
150 2Z3Y F2N 2.99003
151 5BUK FAD 2.99003
152 6GAS FAD 2.99003
153 4XQC NAD 2.99003
154 6FHO FAD 2.99003
155 2GMH FAD 2.99003
156 5KOX FAD 2.99003
157 2XVE FAD 2.99003
158 3OZ2 FAD 2.99003
159 3FZG SAM 3
160 1XHL NDP 3.0303
161 2ZL4 ALA ALA ALA ALA 3.06122
162 3M3E GAL A2G NPO 3.10559
163 1GET FAD 3.11111
164 1GET NAP 3.11111
165 2WSB NAD 3.14961
166 4P83 U5P 3.2967
167 4N49 SAM 3.32226
168 1ZGA SAH 3.32226
169 4Y9D NAI 3.32226
170 4YKG FAD 3.32226
171 4M52 M52 3.32226
172 4TQG NDP 3.32226
173 4YKG NAD 3.32226
174 4M52 FAD 3.32226
175 5BJX NAD 3.32226
176 5BJX UDP 3.32226
177 3GF4 FAD 3.32226
178 3GF4 UPG 3.32226
179 5VN0 FAD 3.32226
180 1FL2 FAD 3.32226
181 1DKU AP2 3.32226
182 1NAA ABL 3.32226
183 1I8T FAD 3.32226
184 1NAA 6FA 3.32226
185 5VN0 NAI 3.32226
186 1GPE FAD 3.32226
187 2A8X FAD 3.32226
188 4GLW NMN 3.32226
189 4L2I FAD 3.32226
190 1GR0 NAD 3.32226
191 2YVF FAD 3.32226
192 2YVF NAD 3.32226
193 3WGT QSC 3.32226
194 3WGT FAD 3.32226
195 5NC1 NAG 3.37553
196 5OVK NDP 3.51562
197 5DEX GLY 3.53357
198 2JBH 5GP 3.55556
199 2GL0 ADN 3.59281
200 2BGM NAJ 3.59712
201 3GWZ SAH 3.65448
202 4D04 NAP 3.65448
203 4D04 FAD 3.65448
204 1ELI PYC 3.65448
205 3GXO SAH 3.65448
206 2HQM FAD 3.65448
207 5CX8 TG6 3.65448
208 3CTY FAD 3.65448
209 1SOW NAD 3.65448
210 6AIN FAD 3.65448
211 1C0I FAD 3.65448
212 1C0I BE2 3.65448
213 3NTA FAD 3.65448
214 2RGJ FAD 3.65448
215 4YT4 FE9 3.65448
216 6AM8 TRP 3.65448
217 3AYI FAD 3.65448
218 3AYI HCI 3.65448
219 3LXD FAD 3.65448
220 4II2 ATP 3.68098
221 4CS9 AMP 3.7037
222 2VT3 ATP 3.72093
223 1LVW TYD 3.72881
224 2HNK SAH 3.76569
225 4RL4 PPV 3.77358
226 4WZ6 ATP 3.7931
227 2CBZ ATP 3.79747
228 3DUV KDO 3.81679
229 5GVR LMR 3.84615
230 4ZCC FAD 3.86905
231 4ZCC NAI 3.86905
232 1T57 FMN 3.8835
233 2P3V SRT 3.90625
234 1I1N SAH 3.9823
235 5ERG SAM 3.98671
236 1ZK7 FAD 3.98671
237 4J36 1HR 3.98671
238 4J36 FAD 3.98671
239 1Y8Q ATP 3.98671
240 5MIT NAP 3.98671
241 5MIT FAD 3.98671
242 2R4J 13P 3.98671
243 2R4J FAD 3.98671
244 1RRC ADP 3.98671
245 4KGD FAD 3.98671
246 4KGD TDP 3.98671
247 2GN4 NDP 3.98671
248 3UOY NAP 3.98671
249 3UOY FAD 3.98671
250 1XHC FAD 3.98671
251 3LZW FAD 3.98671
252 3LZW NAP 3.98671
253 6GAR FAD 3.98671
254 1KYZ SAH 3.98671
255 2GN4 UD1 3.98671
256 4EIP FAD 3.98671
257 2YG3 FAD 3.98671
258 4TQK NAG 3.98671
259 1M2K APR 4.01606
260 4GUS FAD 4.03226
261 4GUT FAD 4.03226
262 4HSU FAD 4.03226
263 5GM1 SAH 4.0404
264 3LKZ SFG 4.04984
265 5HCF BGC 4.05904
266 3HVJ 705 4.0724
267 4QM7 GTP 4.09357
268 1H5R THM 4.09556
269 1H5S TMP 4.09556
270 2A14 SAH 4.18251
271 2PXX SAH 4.18605
272 2HXW FLC 4.21941
273 6CI9 NAP 4.2471
274 1NW5 SAM 4.31894
275 2WPF FAD 4.31894
276 2WPF WPF 4.31894
277 4DMG SAM 4.31894
278 5TWB FAD 4.31894
279 1FP2 SAH 4.31894
280 3TKY SAH 4.31894
281 4M3P HCS 4.31894
282 3KLJ FAD 4.31894
283 5Y1G NAD 4.31894
284 5Y1G AKB 4.31894
285 5KMS FAD 4.31894
286 1VJT NAD 4.31894
287 2OG2 MLI 4.31894
288 1KNR FAD 4.31894
289 2PK3 A2R 4.36137
290 2PX8 SAH 4.46097
291 1IY8 NAD 4.49438
292 4BLW AMP 4.49827
293 5JGL SAM 4.49827
294 4BLW SAH 4.49827
295 4CQM NAP 4.5082
296 3WDM ADN 4.5977
297 5XLX SAH 4.60993
298 5JJR SAH 4.65116
299 4B2D SER 4.65116
300 1V59 FAD 4.65116
301 1UWK URO 4.65116
302 1UWK NAD 4.65116
303 3C6K SPD 4.65116
304 1X87 NAD 4.65116
305 2BRY FAD 4.65116
306 2ZXI FAD 4.65116
307 4TXI FAD 4.65116
308 3C6K MTA 4.65116
309 1OBB NAD 4.65116
310 1QO8 FAD 4.65116
311 4D5G FAD 4.65116
312 1V59 NAD 4.65116
313 4D5G TPP 4.65116
314 4CNK FAD 4.65116
315 3FPZ AHZ 4.65116
316 2E5V FAD 4.65116
317 4MIG G3F 4.65116
318 5J60 FAD 4.65116
319 3CGB FAD 4.65116
320 5K0A FAD 4.65116
321 1Q1R FAD 4.65116
322 3FGZ BEF 4.6875
323 3KIF GDL 4.71698
324 2BZG SAH 4.74138
325 2PZE ATP 4.80349
326 5VJN IR8 4.81283
327 4YAG NAI 4.84429
328 5CUQ NSC 4.86891
329 5K7U SAM 4.88889
330 3LCV SAM 4.98221
331 5MW4 5JU 4.98339
332 3QOX SAH 4.98339
333 5JCA FAD 4.98339
334 1FP1 SAH 4.98339
335 5JCA NDP 4.98339
336 3ICT ADP 4.98339
337 3ICS ADP 4.98339
338 1JS8 MAN MAN BMA 4.98339
339 5W7R SAH 4.98339
340 3ICT FAD 4.98339
341 2QQF A1R 4.98339
342 3ICS FAD 4.98339
343 3ICR FAD 4.98339
344 2OD9 A1R NCA 4.98339
345 4JDR FAD 4.98339
346 3NT6 FAD 4.98339
347 3VPH OXM 4.98339
348 4NTC FAD 4.98339
349 2ZIF SAM 5.05051
350 1SZD APR 5.05051
351 2WA2 SAM 5.07246
352 3MB5 SAM 5.09804
353 1XCL SAH 5.10638
354 3THR C2F 5.11945
355 6F9Q NAD 5.14706
356 5FEU NAP 5.15464
357 5IL1 SAM 5.18868
358 2JAH NDP 5.26316
359 2P41 SAH 5.31561
360 4KRI SAH 5.31561
361 1RJW ETF 5.31561
362 2JHP SAH 5.31561
363 1EFV FAD 5.31561
364 1EFV AMP 5.31561
365 3GD4 NAD 5.31561
366 3GD4 FAD 5.31561
367 2NVK FAD 5.31561
368 4TM3 FAD 5.31561
369 2NVK NAP 5.31561
370 4YNU FAD 5.31561
371 4YNU LGC 5.31561
372 6GKV SAH 5.31561
373 1VL8 NAP 5.31561
374 3OJO NAD 5.31561
375 3EVF SAH 5.41516
376 3EVF GTA 5.41516
377 2NV2 GLN 5.44218
378 4NBW NAD 5.44747
379 5YJI 8WO 5.6338
380 5YJI SAH 5.6338
381 1G55 SAH 5.64784
382 1U2Z SAH 5.64784
383 5KOK SAH 5.64784
384 2AWN ADP 5.64784
385 2Q28 ADP 5.64784
386 5KOK S9T 5.64784
387 5DNK SAH 5.64784
388 2RAB NAD 5.64784
389 4AP3 NAP 5.64784
390 4AP3 FAD 5.64784
391 4MOP 2H5 5.64784
392 2RGO FAD 5.64784
393 2RAB FAD 5.64784
394 4YSX FAD 5.64784
395 4JNA FAD 5.64784
396 4G5H NAP 5.64784
397 4G5H UD7 5.64784
398 2VL8 CTS 5.64784
399 5KOK R9T 5.64784
400 2XT3 ADP 5.64784
401 1B0U ATP 5.72519
402 1XX6 ADP 5.75916
403 1G6H ADP 5.83658
404 5FFF NAP 5.83658
405 5UFN SAH 5.88235
406 3PH4 AOS 5.91716
407 6ECT SAM 5.98007
408 1D4D FAD 5.98007
409 3QFA FAD 5.98007
410 2JK0 ASP 5.98007
411 4B63 NAP 5.98007
412 4B63 ORN 5.98007
413 4B63 FAD 5.98007
414 5FPE 3TR 5.98007
415 1P1C SAH 6.03015
416 2CUL FAD 6.03448
417 1I7E IBS 6.03774
418 1QAN SAH 6.14754
419 4U00 ADP 6.14754
420 5N53 8NB 6.15385
421 1R18 SAH 6.1674
422 5E1M SAH 6.22407
423 5E1M PRO PRO LYS ARG ILE ALA 6.22407
424 6FLZ MMA 6.25
425 5U19 827 6.31229
426 5U19 SAH 6.31229
427 6BQ6 TER 6.31229
428 5HJM MTA 6.31229
429 4OPC PGT 6.31229
430 4OPC FDA 6.31229
431 3AXB PRO 6.31229
432 3AXB FAD 6.31229
433 3ML1 MGD 6.31229
434 5ULP KB1 6.34328
435 3G2O SAM 6.35452
436 1QB7 ADE 6.35593
437 1MZV AMP 6.38298
438 6BJO DUY 6.4
439 2EWM NAD 6.4257
440 2W58 ADP 6.43564
441 6B92 SAH 6.46258
442 1XTT U5P 6.48148
443 1L7N ALF 6.63507
444 5N5D SAM 6.63717
445 3MAG SAH 6.64452
446 6F5W KG1 6.64452
447 3HDY GDU 6.64452
448 3HDY FDA 6.64452
449 3HDY FAD 6.64452
450 5JCM ISD 6.64452
451 5JCM FAD 6.64452
452 5JCM NAD 6.64452
453 6C8R EQV 6.64452
454 6C8R SAH 6.64452
455 6C5B SAH 6.64452
456 5BRT CH9 6.64452
457 5BRT FAD 6.64452
458 2WHX ADP 6.64452
459 5MZN ADP 6.64452
460 4D86 ADP 6.64452
461 3P2E SAH 6.66667
462 1XTP SAI 6.69291
463 1FWV SGA MAG FUC 6.71642
464 3MCT SAH 6.73401
465 6EQS BV8 6.90909
466 2VDV SAM 6.91057
467 5E8J SAH 6.97674
468 5E9W SAH 6.97674
469 1Q9I TEO 6.97674
470 1Q9I FAD 6.97674
471 4NTD FAD 6.97674
472 2Q0L FAD 6.97674
473 3A27 SAM 6.98529
474 3T7S SAM 7.08955
475 4NEC SAH 7.19697
476 1O97 FAD 7.19697
477 1O97 AMP 7.19697
478 3LAD FAD 7.30897
479 4PLT NAI 7.30897
480 2IV2 MGD 7.30897
481 2DKH 3HB 7.30897
482 2DKH FAD 7.30897
483 5GSN FAD 7.30897
484 5GSN NAP 7.30897
485 1E1M NAP 7.30897
486 1E1M FAD 7.30897
487 4PIO AVI 7.30897
488 2XVF FAD 7.30897
489 4PIO SAH 7.30897
490 4PLT OXM 7.30897
491 4OBW SAM 7.393
492 5Z2F PDC 7.54717
493 2YJP CYS 7.56014
494 6GFK SAH 7.56972
495 3K8D KDO 7.57576
496 3PFG TLO 7.60456
497 3PFG SAM 7.60456
498 4RVG TYD 7.6412
499 4RVG SAM 7.6412
500 4USR FAD 7.6412
501 1XDS SAM 7.6412
502 1KPH SAH 7.66551
503 1KPG SAH 7.66551
504 1TPY SAH 7.66551
505 1UAY ADN 7.85124
506 2ZFU SAH 7.90698
507 1TE2 PGA 7.9646
508 3S1S SAH 7.97342
509 5THY SAH 7.97342
510 4DCM SAM 7.97342
511 4AZW SAM 7.97342
512 1GTE FAD 7.97342
513 2GK6 ADP 7.97342
514 2IXB A2G 7.97342
515 2IXB NAD 7.97342
516 1QZZ SAM 7.97342
517 3ELW SAM 8
518 3ELW GP3 8
519 1VBO MAN MAN MAN 8.05369
520 5GWX SAM 8.09859
521 5GWX SAR 8.09859
522 4R6W PC 8.13953
523 4R6W SAH 8.13953
524 1HGX 5GP 8.19672
525 3U31 NAD 8.27586
526 5FWA J7C 8.30565
527 3AB1 FAD 8.30565
528 4BJZ FAD 8.30565
529 4BJZ P3A 8.30565
530 1V6A TRE 8.30565
531 2VVL FAD 8.30565
532 2VVM FAD 8.30565
533 3A06 NDP 8.30565
534 1L3I SAH 8.33333
535 3AD8 NAD 8.37438
536 3AD8 FAD 8.37438
537 3AD8 PYC 8.37438
538 4EMI NAD 8.53659
539 4EMI FAD 8.53659
540 5E72 SAM 8.63787
541 5WP4 SAH 8.63787
542 6ER9 FAD 8.63787
543 6ER9 NAP 8.63787
544 5JWC FAD 8.63787
545 4USQ FAD 8.63787
546 4PPF FLC 8.63787
547 5TSH ADP 8.63787
548 6F5Z SAH 8.65801
549 1DQN IMU 8.69565
550 3EVG SAH 8.72727
551 3GCZ SAM 8.9701
552 5X62 SAH 8.9701
553 1T26 GBD 8.9701
554 1T26 NAI 8.9701
555 1I9Z 2IP 8.9701
556 1RYI GOA 8.9701
557 1RYI FAD 8.9701
558 4ZVV GN0 8.9701
559 4ZVV NAD 8.9701
560 5FTW SAH 8.98438
561 2DT5 NAD 9.00474
562 4FC7 COA 9.02527
563 4FC7 NAP 9.02527
564 2GAG NAD 9.04762
565 2GAG FAD 9.04762
566 3MQ2 SAH 9.17431
567 3DXY SAM 9.17431
568 4JLS 3ZE 9.21053
569 1BC5 SAH 9.29368
570 5THZ SAH 9.30233
571 5YF1 SFG 9.30233
572 5YF1 8V0 9.30233
573 5OC1 FAD 9.30233
574 2VHW NAI 9.30233
575 5FA8 SAM 9.31677
576 5D4V SAH 9.32836
577 5ZZ6 ADP 9.61539
578 5ZZ6 NAD 9.61539
579 3VYW SAM 9.63455
580 3LST SAH 9.63455
581 2O07 SPD 9.63455
582 2O07 MTA 9.63455
583 3A4M ADP 9.63455
584 2PS1 ORO 9.73451
585 5MGZ SAH 9.74576
586 3BBH SFG 9.7561
587 1UPF URF 9.82143
588 1KYQ NAD 9.85401
589 1ZEM NAD 9.92366
590 4RSL FAD 9.96678
591 1UP7 NAD 9.96678
592 2A92 NAI 9.96678
593 3GDN HBX 9.96678
594 3GDN FAD 9.96678
595 3F8D FAD 9.96678
596 4A6D SAM 9.96678
597 3COB ADP 9.96678
598 4XUC SAM 10.0917
599 4XUC 43G 10.0917
600 1VE3 SAM 10.1322
601 6FDF SAH 10.299
602 4YRY FAD 10.299
603 4YRY NAD 10.299
604 1V5F TPP 10.299
605 1V5F FAD 10.299
606 5LOG SAH 10.3004
607 3Q87 SAM 10.4
608 3A28 NAD 10.4651
609 2PT9 2MH 10.5919
610 2PT9 S4M 10.5919
611 4REP FAD 10.6312
612 3ABI NAD 10.6312
613 5BSZ SAH 10.8
614 3H2B SAH 10.8374
615 1RP0 AHZ 10.9155
616 5W7K SAH 10.9635
617 5I39 FAD 10.9635
618 5U8U FAD 10.9635
619 6F97 FAD 10.9635
620 2YVJ NAI 11.0092
621 4YUW S4M 11.2957
622 4YUW 4JU 11.2957
623 3S5W FAD 11.2957
624 1H82 FAD 11.2957
625 1H82 GZZ 11.2957
626 1GPM AMP 11.2957
627 1JQ3 AAT 11.4865
628 1NVM NAD 11.5385
629 3A25 SAM 11.6279
630 4IV9 FAD 11.6279
631 4Z24 FAD 11.6279
632 3WV8 ATP 11.9266
633 2UYQ SAM 11.9355
634 6FP4 FAD 11.9601
635 6FP4 E1T 11.9601
636 5W7M SAH 11.9601
637 3NTD FAD 11.9601
638 1JNR FAD 12
639 2I7C AAT 12.0141
640 2OBF SAH 12.1107
641 2OBF F83 12.1107
642 4KIB SAH 12.2924
643 1F3L SAH 12.2924
644 1KJ8 GAR 12.2924
645 2FKA BEF 12.4031
646 1Z3C SA8 12.4161
647 5JE0 SAH 12.5506
648 5JE0 AZ8 12.5506
649 2WZG UPG 12.6246
650 6EL3 NAP 12.6246
651 3ZNN 4WL 12.6246
652 3ZNN FAD 12.6246
653 5BW4 SAM 12.7341
654 5J5Z FAD 12.9568
655 2F5Z FAD 12.9568
656 1YY5 FAD 12.9568
657 2E7Z MGD 12.9568
658 1RSG FAD 12.9568
659 3RNM FAD 12.9568
660 2IID FAD 12.9568
661 2IID PHE 12.9568
662 5CIC 51R 12.963
663 6DUB SAH 13.0631
664 1G60 SAM 13.0769
665 3ZIA ADP 13.1148
666 3JWH SAH 13.3641
667 5YJF SAH 13.3803
668 5YJF 8WO 13.3803
669 5TTJ FAD 13.9535
670 4RUS NAG 14.2857
671 2PWY SAH 14.3411
672 4F8L AES 14.4828
673 1SQF SAM 14.6179
674 5XNC MTA 14.6179
675 1YBH FAD 14.6179
676 1L1E SAH 14.6341
677 3BXO SAM 14.6444
678 4NBU NAI 14.8
679 1DL5 SAH 14.9502
680 2GV8 FAD 14.9502
681 2GVC FAD 14.9502
682 1VQW FAD 14.9502
683 1LSS NAD 15
684 6FHQ DE5 15.5172
685 6IS0 SAH 15.6146
686 1G8K MGD 15.7895
687 4PLG OXM 15.9468
688 4PLG NAI 15.9468
689 4EMJ FAD 17.757
690 3OU2 SAH 18.8073
691 1O5O U5P 19.0045
692 4POO SAM 19.5
693 2HMT NAI 20.1389
694 1E6E FAD 20.3125
695 2XVM SAH 20.603
696 3LN9 FLC 24.4604
697 5EB4 FAD 24.9169
698 4J56 FAD 27.193
699 1XXA ARG 28.2051
700 5YEC ATP 31.9328
701 4GQB 0XU 40.9091
702 5FA5 MTA 45
Pocket No.: 2; Query (leader) PDB : 1N2X; Ligand: SAM; Similar sites found with APoc: 75
This union binding pocket(no: 2) in the query (biounit: 1n2x.bio1) has 26 residues
No: Leader PDB Ligand Sequence Similarity
1 2GUD MAN None
2 2NU5 NAG None
3 2NUO BGC None
4 2GUC MAN None
5 2HYR BGC GLC None
6 2HYQ MAN MAN None
7 2GUD BMA None
8 6BKK 308 None
9 4BWL MN9 1.3289
10 1WOG 16D 1.66113
11 5A9A UTP 2.05761
12 4AU8 Z3R 2.36486
13 1FUR MLT 2.65781
14 4EUE NAI 2.65781
15 3HP8 SUC 2.72727
16 5C9P FUC 2.99003
17 5KOX RFP 2.99003
18 2Q1W NAD 2.99003
19 4YDD MD1 2.99003
20 4YDD MGD 2.99003
21 6CFC BLG 2.99003
22 4I5I 4I5 3.13589
23 5LQ8 GB 3.19149
24 4HA6 FAD 3.32226
25 1MUU NAD 3.32226
26 2Q1S NAI 3.32226
27 5WGR FAD 3.32226
28 1MV8 NAD 3.32226
29 4DSG FAD 3.32226
30 4DSG UDP 3.32226
31 4PI8 NAG AMU 3.94737
32 3VM7 GLC 3.98671
33 1DNP MHF 3.98671
34 5NMX NAP 3.98671
35 5NMX FAD 3.98671
36 4ITU 1HS 4.08922
37 1B4B ARG 4.22535
38 3GMB FAD 4.31894
39 2G50 PYR 4.65116
40 2HIM ASN 4.65116
41 5MZI FYK 4.98339
42 5MZI FAD 4.98339
43 2Y6Q I7T 4.98339
44 2Y6Q FAD 4.98339
45 2BZ1 TAU 5.10204
46 2PFY PCA 5.31561
47 5OFW 9TW 5.38117
48 2QA1 FAD 5.64784
49 2AG5 NAD 5.69106
50 4GK9 MAN BMA MAN MAN MAN 5.73477
51 4YMU ATP 5.83333
52 5FFF 5XC 5.83658
53 2PFZ PCA 6.31229
54 3HEE R5P 6.71141
55 3HQP OXL 6.97674
56 3WWX DIA 6.97674
57 1TLG GAL 7.2
58 5GSN MMZ 7.30897
59 5L95 AMP 7.5
60 2AE2 PTO 7.69231
61 2AE2 NAP 7.69231
62 4EDF UPG 8.30565
63 2Q4G CIT 8.52713
64 3QVP FAD 8.63787
65 3H4S ADP 8.63787
66 4FRZ ADP 8.63787
67 5ZRR 9J3 9.43396
68 2D2F ADP 9.6
69 1OBD AMP 9.96678
70 3SQP FAD 10.6312
71 5XDR ADP 10.6312
72 1SQL GUN 10.9589
73 1GPM CIT 11.2957
74 6A20 ADP 11.6279
75 4RUS NDG 14.2857
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