Receptor
PDB id Resolution Class Description Source Keywords
1M7H 2 Å EC: 2.7.1.25 CRYSTAL STRUCTURE OF APS KINASE FROM PENICILLIUM CHRYSOGENUM: STRUCTURE WITH APS SOAKED OUT OF ONE DIMER PENICILLIUM CHRYSOGENUM APS KINASE ADENYLYLSULFATE KINASE TRANSFERASE SULFATE METABOLISM NUCLEOTIDE 2 KINASE
Ref.: LIGAND-INDUCED STRUCTURAL CHANGES IN ADENOSINE 5'-PHOSPHOSULFATE KINASE FROM PENICILLIUM CHRYSOGENUM. BIOCHEMISTRY V. 41 13672 2002
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ADP A:1301;
B:1302;
C:1304;
D:1305;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
submit data
427.201 C10 H15 N5 O10 P2 c1nc(...
ADX B:1303;
D:1306;
Valid;
Valid;
none;
none;
submit data
427.284 C10 H14 N5 O10 P S c1nc(...
SO4 A:1002;
A:1005;
A:1006;
A:1009;
A:1012;
B:1003;
B:1007;
C:1001;
C:1004;
C:1008;
C:1011;
D:1010;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
submit data
96.063 O4 S [O-]S...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1M7G 1.43 Å EC: 2.7.1.25 CRYSTAL STRUCTURE OF APS KINASE FROM PENICILLIUM CHRYSOGENUM STRUCTURE WITH ADP AND APS PENICILLIUM CHRYSOGENUM APS KINASE ADENYLYLSULFATE KINASE TRANSFERASE SULFATE METNUCLEOTIDE 2 KINASE
Ref.: LIGAND-INDUCED STRUCTURAL CHANGES IN ADENOSINE 5'-PHOSPHOSULFATE KINASE FROM PENICILLIUM CHRYSOGEN BIOCHEMISTRY V. 41 13672 2002
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 7 families.
1 1M7G - ADX C10 H14 N5 O10 P S c1nc(c2c(n....
2 1M7H - ADX C10 H14 N5 O10 P S c1nc(c2c(n....
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 6 families.
1 1M7G - ADX C10 H14 N5 O10 P S c1nc(c2c(n....
2 1M7H - ADX C10 H14 N5 O10 P S c1nc(c2c(n....
50% Homology Family (8)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 2PEZ - GGZ C10 H13 N5 O12 P2 S c1nc(c2c(n....
2 2PEY - DAT C10 H15 N5 O9 P2 c1nc(c2c(n....
3 5CB8 Ki = 18.2 uM ADX C10 H14 N5 O10 P S c1nc(c2c(n....
4 3UIE - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
5 2OFW Ki = 17 uM ADX C10 H14 N5 O10 P S c1nc(c2c(n....
6 2OFX - PPS C10 H15 N5 O13 P2 S c1nc(c2c(n....
7 1M7G - ADX C10 H14 N5 O10 P S c1nc(c2c(n....
8 1M7H - ADX C10 H14 N5 O10 P S c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ADP; Similar ligands found: 435
No: Ligand ECFP6 Tc MDL keys Tc
1 ADP 1 1
2 ATP 0.9 1
3 A2D 0.895522 0.971831
4 AQP 0.887324 1
5 5FA 0.887324 1
6 AP5 0.884058 0.971831
7 B4P 0.884058 0.971831
8 BA3 0.869565 0.971831
9 AN2 0.84507 0.985915
10 M33 0.833333 0.958333
11 ACQ 0.826667 0.972222
12 A 0.823529 0.971429
13 AMP 0.823529 0.971429
14 ACP 0.821918 0.972222
15 AR6 0.810811 0.971831
16 APR 0.810811 0.971831
17 ANP 0.802632 0.972222
18 AD9 0.8 0.972222
19 AGS 0.8 0.945946
20 SAP 0.8 0.945946
21 ADX 0.783784 0.873418
22 CA0 0.783784 0.945205
23 TAT 0.779221 0.958904
24 AMP MG 0.774648 0.891892
25 50T 0.773333 0.958333
26 ABM 0.763889 0.917808
27 APC 0.763158 0.958904
28 PRX 0.763158 0.893333
29 ATF 0.759494 0.958904
30 A22 0.753086 0.985915
31 A12 0.743243 0.958904
32 AP2 0.743243 0.958904
33 ADP MG 0.736842 0.905405
34 SRA 0.736111 0.918919
35 ADQ 0.73494 0.945205
36 25L 0.732558 0.985915
37 ADP BEF 0.727273 0.881579
38 BEF ADP 0.727273 0.881579
39 5AL 0.725 0.931507
40 2A5 0.717949 0.918919
41 A1R 0.714286 0.907895
42 AU1 0.714286 0.972222
43 ADP PO3 0.708861 0.943662
44 PAP 0.708861 0.985714
45 ATR 0.708861 0.971429
46 SRP 0.707317 0.906667
47 7D3 0.706667 0.905405
48 25A 0.702381 0.971831
49 ATP MG 0.7 0.905405
50 OAD 0.697674 0.945205
51 RBY 0.6875 0.932432
52 ADV 0.6875 0.932432
53 00A 0.686047 0.883117
54 5SV 0.682353 0.848101
55 8QN 0.682353 0.931507
56 OOB 0.682353 0.931507
57 3OD 0.681818 0.945205
58 BIS 0.681818 0.933333
59 ADP ALF 0.674699 0.87013
60 ALF ADP 0.674699 0.87013
61 AMO 0.674419 0.932432
62 4AD 0.674419 0.92
63 PAJ 0.674419 0.884615
64 GAP 0.670732 0.893333
65 MAP 0.670588 0.945946
66 DLL 0.666667 0.931507
67 ANP MG 0.666667 0.894737
68 VO4 ADP 0.666667 0.931507
69 AHX 0.666667 0.896104
70 ADP VO4 0.666667 0.931507
71 PTJ 0.662921 0.896104
72 3UK 0.659091 0.918919
73 SON 0.658228 0.932432
74 LAD 0.651685 0.860759
75 WAQ 0.651685 0.883117
76 PR8 0.651685 0.85
77 ITT 0.65 0.943662
78 7D4 0.65 0.905405
79 G5P 0.648936 0.921053
80 RAB 0.647059 0.84507
81 ADN 0.647059 0.84507
82 XYA 0.647059 0.84507
83 TXA 0.644444 0.932432
84 1ZZ 0.644444 0.839506
85 ME8 0.644444 0.839506
86 NB8 0.644444 0.896104
87 FYA 0.644444 0.905405
88 6AD 0.642857 0.909091
89 ADP BMA 0.640449 0.918919
90 G3A 0.638298 0.921053
91 DAL AMP 0.632184 0.905405
92 AFH 0.631579 0.884615
93 9SN 0.630435 0.871795
94 GTA 0.625 0.886076
95 YAP 0.623656 0.894737
96 FA5 0.623656 0.906667
97 UP5 0.622449 0.92
98 XAH 0.617021 0.839506
99 AV2 0.616279 0.917808
100 AOC 0.615385 0.821918
101 48N 0.612245 0.896104
102 4UV 0.610526 0.894737
103 TXD 0.606061 0.907895
104 DND 0.606061 0.932432
105 NAX 0.606061 0.873418
106 NXX 0.606061 0.932432
107 NAI 0.606061 0.907895
108 6V0 0.606061 0.896104
109 5N5 0.605634 0.819444
110 5AS 0.604938 0.77907
111 A4P 0.60396 0.843373
112 DAT 0.60241 0.905405
113 A2R 0.602273 0.985915
114 TXE 0.6 0.907895
115 OMR 0.6 0.851852
116 4UU 0.597938 0.894737
117 A A 0.597826 0.944444
118 A4D 0.597222 0.819444
119 5CD 0.597222 0.805556
120 AP0 0.594059 0.896104
121 4TC 0.594059 0.896104
122 A3P 0.592593 0.971429
123 139 0.592233 0.873418
124 T5A 0.592233 0.841463
125 7D5 0.592105 0.878378
126 ATP A A A 0.589474 0.930556
127 LAQ 0.585859 0.839506
128 MYR AMP 0.585106 0.817073
129 YLP 0.58 0.819277
130 UPA 0.578431 0.907895
131 7DD 0.578313 0.985714
132 ADJ 0.576923 0.851852
133 3AM 0.576923 0.929577
134 COD 0.575472 0.811765
135 NAD 0.575472 0.931507
136 3AT 0.574713 0.971831
137 JB6 0.574468 0.883117
138 4UW 0.574257 0.860759
139 EP4 0.573333 0.753247
140 A2P 0.573171 0.957143
141 CNA 0.571429 0.932432
142 TYM 0.568627 0.906667
143 PPS 0.568182 0.873418
144 TYR AMP 0.56701 0.881579
145 DTA 0.565789 0.786667
146 M2T 0.565789 0.734177
147 AR6 AR6 0.565657 0.917808
148 A3D 0.564815 0.918919
149 3DH 0.564103 0.773333
150 G5A 0.563218 0.77907
151 YLB 0.563107 0.819277
152 YLC 0.563107 0.839506
153 AMP DBH 0.561224 0.893333
154 MTA 0.558442 0.773333
155 DTP 0.556818 0.905405
156 AHZ 0.554455 0.817073
157 NA7 0.553191 0.958904
158 IOT 0.552381 0.831325
159 7MD 0.55 0.8625
160 ZAS 0.55 0.766234
161 IMO 0.548781 0.929577
162 YLA 0.54717 0.819277
163 NAE 0.544643 0.894737
164 TAD 0.544554 0.884615
165 A5A 0.544444 0.807229
166 2AM 0.544304 0.943662
167 TSB 0.543478 0.819277
168 6RE 0.54321 0.759494
169 AYB 0.542056 0.809524
170 NAQ 0.539823 0.871795
171 V3L 0.539326 0.971831
172 ARG AMP 0.539216 0.829268
173 AF3 ADP 3PG 0.538462 0.8375
174 SSA 0.538462 0.8
175 LA8 ALF 3PG 0.538462 0.8375
176 ALF ADP 3PG 0.538462 0.8375
177 ZID 0.535088 0.918919
178 LPA AMP 0.533981 0.817073
179 54H 0.532609 0.788235
180 52H 0.532609 0.77907
181 VMS 0.532609 0.788235
182 BTX 0.53211 0.841463
183 J7C 0.53012 0.769231
184 A3N 0.53012 0.786667
185 5X8 0.528736 0.763158
186 BT5 0.527273 0.831325
187 5CA 0.526882 0.8
188 53H 0.526882 0.77907
189 ARU 0.526316 0.860759
190 EAD 0.525862 0.873418
191 RGT 0.525253 0.958904
192 OVE 0.52439 0.905405
193 S4M 0.52381 0.666667
194 7DT 0.522727 0.985714
195 GDP 0.522222 0.92
196 DDS 0.522222 0.878378
197 AVV 0.521277 0.896104
198 NDE 0.521008 0.932432
199 7MC 0.518868 0.841463
200 DSH 0.518072 0.725
201 MAO 0.517647 0.759036
202 LSS 0.515789 0.761364
203 DSZ 0.515789 0.8
204 NSS 0.515789 0.8
205 P5A 0.515464 0.744444
206 DZD 0.513514 0.884615
207 NVA LMS 0.510417 0.761364
208 12D 0.509615 0.785714
209 NAD IBO 0.509091 0.87013
210 M24 0.508772 0.85
211 YLY 0.508772 0.809524
212 P1H 0.508333 0.851852
213 5AD 0.506849 0.746479
214 GJV 0.505882 0.75
215 LEU LMS 0.505155 0.761364
216 G A A A 0.504505 0.871795
217 4TA 0.504505 0.807229
218 NAJ PZO 0.504425 0.848101
219 KAA 0.5 0.752809
220 NDC 0.5 0.871795
221 7D7 0.5 0.743243
222 71V 0.5 0.907895
223 A3G 0.5 0.8
224 128 0.5 0.776471
225 GSU 0.5 0.77907
226 N0B 0.495726 0.819277
227 NJP 0.495495 0.945946
228 ODP 0.495495 0.909091
229 2SA 0.494624 0.932432
230 6C6 0.494505 0.881579
231 SFG 0.494382 0.75
232 0WD 0.491071 0.921053
233 YSA 0.490196 0.77907
234 PO4 PO4 A A A A PO4 0.489796 0.902778
235 6IA 0.48913 0.8375
236 SAM 0.48913 0.690476
237 A7D 0.488636 0.776316
238 6FA 0.488 0.841463
239 FB0 0.487805 0.804598
240 NAJ PYZ 0.487179 0.85
241 IDP 0.483516 0.918919
242 A5D 0.483516 0.786667
243 SA8 0.483516 0.707317
244 MHZ 0.483146 0.697674
245 PGS 0.483146 0.883117
246 D5M 0.482353 0.878378
247 DA 0.482353 0.878378
248 NEC 0.482353 0.746667
249 NIA 0.481928 0.822785
250 Y3J 0.480519 0.726027
251 FAD 0.480315 0.851852
252 FAS 0.480315 0.851852
253 FDA 0.48 0.833333
254 N6P 0.479592 0.915493
255 GGZ 0.479167 0.825
256 SAH 0.478261 0.74359
257 SAI 0.478261 0.734177
258 NPW 0.477477 0.886076
259 NDP 0.477477 0.921053
260 AAM 0.476744 0.971429
261 AMZ 0.47561 0.916667
262 C2R 0.47561 0.90411
263 A A A 0.474747 0.905405
264 GTP 0.473684 0.92
265 U A G G 0.473684 0.883117
266 SMM 0.473684 0.686047
267 TXP 0.473214 0.921053
268 NZQ 0.473214 0.909091
269 A3S 0.47191 0.810811
270 AMP NAD 0.470588 0.881579
271 SFD 0.46875 0.734043
272 AIR 0.468354 0.901408
273 AAT 0.468085 0.707317
274 EEM 0.468085 0.690476
275 Z5A 0.466667 0.77907
276 7C5 0.466667 0.818182
277 J7V 0.466667 0.833333
278 62F 0.465649 0.8625
279 FAY 0.462121 0.8625
280 ETB 0.461538 0.833333
281 DCA 0.461538 0.823529
282 A3T 0.461538 0.821918
283 A6D 0.46 0.722892
284 A U 0.459459 0.87013
285 6K6 0.459184 0.930556
286 GEK 0.459184 0.7375
287 RFL 0.458647 0.821429
288 S7M 0.458333 0.690476
289 NAP 0.458333 0.945205
290 4YB 0.457944 0.761364
291 WSA 0.454545 0.788235
292 TAP 0.454545 0.907895
293 FNK 0.454545 0.804598
294 COA 0.453782 0.823529
295 0T1 0.453782 0.823529
296 101 0.453488 0.878378
297 XNP 0.452174 0.873418
298 NA0 0.45082 0.932432
299 7RP 0.448276 0.928571
300 GP3 0.446809 0.921053
301 TM1 0.446602 0.77381
302 APU 0.446429 0.894737
303 PUA 0.445378 0.884615
304 V1N 0.443396 0.917808
305 7RA 0.443182 0.957747
306 30N 0.442623 0.752688
307 CAO 0.442623 0.795455
308 AMX 0.442623 0.833333
309 COS 0.442623 0.804598
310 ACK 0.44186 0.861111
311 QQY 0.44186 0.815789
312 649 0.441441 0.744444
313 0UM 0.44 0.698795
314 NHD 0.439655 0.905405
315 CMX 0.439024 0.823529
316 SCO 0.439024 0.823529
317 GCP 0.438776 0.896104
318 8BR 0.438202 0.906667
319 GNH 0.4375 0.907895
320 3AD 0.4375 0.805556
321 62X 0.435644 0.666667
322 ACO 0.435484 0.795455
323 FCX 0.435484 0.795455
324 FAM 0.435484 0.804598
325 GNP 0.434343 0.896104
326 NMX 0.433071 0.76087
327 MGP 0.43299 0.884615
328 PLP AAD 0.432203 0.741573
329 26A 0.432099 0.763158
330 HAX 0.432 0.804598
331 K15 0.431373 0.682353
332 DG1 0.430894 0.921053
333 1DG 0.430894 0.921053
334 QQX 0.430233 0.805195
335 2VA 0.430108 0.8
336 S8M 0.43 0.759494
337 2MC 0.429688 0.769231
338 3KK 0.428571 0.804598
339 6G0 0.428571 0.884615
340 FYN 0.428571 0.823529
341 P5F 0.428571 0.823529
342 NAD BBN 0.428571 0.841463
343 U G A 0.427481 0.839506
344 AS 0.426966 0.833333
345 FAI 0.426966 0.916667
346 RMB 0.426966 0.873239
347 1RB 0.425287 0.885714
348 MCD 0.425197 0.804598
349 OXK 0.425197 0.804598
350 COK 0.425197 0.804598
351 CA6 0.425197 0.729167
352 SOP 0.425197 0.804598
353 G1R 0.424242 0.907895
354 CC5 0.423077 0.816901
355 SXZ 0.423077 0.710843
356 F2N 0.422535 0.813953
357 NAD CJ3 0.422222 0.811765
358 ANZ 0.422018 0.8
359 CMC 0.421875 0.804598
360 CO6 0.421875 0.804598
361 1VU 0.421875 0.795455
362 ZDA 0.421053 0.864865
363 GDD 0.420561 0.884615
364 GKE 0.420561 0.884615
365 GDC 0.420561 0.884615
366 NFD 0.420168 0.883117
367 GSP 0.42 0.873418
368 D3Y 0.42 0.789474
369 MC4 0.419847 0.76087
370 3L1 0.419753 0.773333
371 3D1 0.419753 0.773333
372 FA9 0.41958 0.864198
373 5GP 0.419355 0.906667
374 G 0.419355 0.906667
375 KB1 0.419048 0.698795
376 SCD 0.418605 0.823529
377 CAJ 0.418605 0.804598
378 2BA 0.417582 0.915493
379 CMP 0.417582 0.901408
380 SO8 0.416667 0.789474
381 N01 0.416667 0.905405
382 VRT 0.416667 0.769231
383 3HC 0.415385 0.813953
384 A1S 0.415385 0.804598
385 BCO 0.415385 0.804598
386 IVC 0.415385 0.813953
387 MLC 0.415385 0.804598
388 1HE 0.415385 0.786517
389 NMN AMP PO4 0.415254 0.87013
390 2FA 0.414634 0.813333
391 MGO 0.414141 0.860759
392 3NZ 0.413462 0.782051
393 MCA 0.412214 0.795455
394 CAA 0.412214 0.813953
395 YE1 0.412214 0.813953
396 COO 0.412214 0.804598
397 GAV 0.411765 0.884615
398 P2P 0.411111 0.902778
399 JLN 0.411111 0.890411
400 ZZB 0.410256 0.77381
401 CNV FAD 0.410072 0.793103
402 SCA 0.409091 0.804598
403 RP1 0.409091 0.842105
404 103 0.409091 0.837838
405 2CP 0.409091 0.795455
406 SP1 0.409091 0.842105
407 PAX 0.408 0.829268
408 FAD NBT 0.407143 0.75
409 NVA 2AD 0.40625 0.74359
410 COW 0.406015 0.795455
411 BYC 0.406015 0.804598
412 2KQ 0.406015 0.786517
413 COF 0.406015 0.786517
414 3CP 0.406015 0.804598
415 IRC 0.406015 0.813953
416 1GZ 0.406015 0.795455
417 HGG 0.406015 0.804598
418 CA8 0.406015 0.729167
419 G2P 0.405941 0.884615
420 SLU 0.404959 0.770115
421 U A C C 0.404959 0.858974
422 RBZ 0.404494 0.849315
423 1CZ 0.404412 0.795455
424 BCA 0.402985 0.795455
425 FAQ 0.402985 0.804598
426 4CA 0.402985 0.795455
427 MTP 0.402439 0.730769
428 8OD 0.402062 0.945205
429 CO7 0.401515 0.804598
430 DAL FAD PER 0.401408 0.809524
431 G2R 0.4 0.884615
432 HXC 0.4 0.786517
433 ENQ 0.4 0.916667
434 GMV 0.4 0.896104
435 GRA 0.4 0.804598
Ligand no: 2; Ligand: ADX; Similar ligands found: 344
No: Ligand ECFP6 Tc MDL keys Tc
1 ADX 1 1
2 A2D 0.816901 0.873418
3 BA3 0.794521 0.873418
4 B4P 0.783784 0.873418
5 ADP 0.783784 0.873418
6 AP5 0.783784 0.873418
7 50T 0.776316 0.839506
8 A 0.774648 0.848101
9 AMP 0.774648 0.848101
10 AN2 0.773333 0.8625
11 CA0 0.763158 0.851852
12 M33 0.763158 0.8625
13 ACP 0.753247 0.851852
14 ATP 0.753247 0.873418
15 AR6 0.74359 0.873418
16 AQP 0.74359 0.873418
17 APR 0.74359 0.873418
18 5FA 0.74359 0.873418
19 PRX 0.74359 0.807229
20 ABM 0.743243 0.82716
21 AD9 0.734177 0.851852
22 SAP 0.734177 0.9
23 AGS 0.734177 0.9
24 AMP MG 0.72973 0.804878
25 A12 0.723684 0.841463
26 AP2 0.723684 0.841463
27 SRA 0.716216 0.875
28 ANP 0.716049 0.851852
29 ACQ 0.716049 0.851852
30 PPS 0.707317 0.974684
31 5AL 0.707317 0.839506
32 ATF 0.698795 0.841463
33 AU1 0.696203 0.851852
34 SRP 0.690476 0.819277
35 APC 0.679012 0.841463
36 ADP MG 0.675 0.817073
37 TAT 0.674699 0.8875
38 A22 0.674419 0.8625
39 ADV 0.670732 0.841463
40 RBY 0.670732 0.841463
41 8QN 0.666667 0.839506
42 OOB 0.666667 0.839506
43 ADP BEF 0.666667 0.797619
44 5SV 0.666667 0.770115
45 25A 0.666667 0.85
46 BEF ADP 0.666667 0.797619
47 4AD 0.659091 0.831325
48 PAJ 0.659091 0.802326
49 A1R 0.659091 0.821429
50 ADQ 0.659091 0.851852
51 AMO 0.659091 0.841463
52 AHX 0.651685 0.811765
53 00A 0.651685 0.8
54 DLL 0.651685 0.839506
55 ADP PO3 0.650602 0.848101
56 3UK 0.644444 0.829268
57 OAD 0.644444 0.851852
58 ATP MG 0.642857 0.817073
59 SON 0.641975 0.819277
60 LAD 0.637363 0.781609
61 PR8 0.637363 0.772727
62 WAQ 0.637363 0.8
63 MAP 0.636364 0.831325
64 GAP 0.635294 0.807229
65 3OD 0.630435 0.851852
66 PTJ 0.630435 0.790698
67 NB8 0.630435 0.811765
68 TXA 0.630435 0.841463
69 1ZZ 0.630435 0.764045
70 BIS 0.630435 0.821429
71 ME8 0.630435 0.784091
72 FYA 0.630435 0.817073
73 25L 0.623656 0.8625
74 ALF ADP 0.62069 0.788235
75 ADP ALF 0.62069 0.788235
76 GGZ 0.617977 0.949367
77 9SN 0.617021 0.790698
78 ADP VO4 0.613636 0.839506
79 ANP MG 0.613636 0.809524
80 VO4 ADP 0.613636 0.839506
81 YAP 0.610526 0.809524
82 FA5 0.610526 0.819277
83 5AS 0.609756 0.894118
84 XYA 0.605634 0.759494
85 ADN 0.605634 0.759494
86 RAB 0.605634 0.759494
87 XAH 0.604167 0.764045
88 DAL AMP 0.6 0.817073
89 AOC 0.6 0.740741
90 4UV 0.597938 0.809524
91 GTA 0.59596 0.784091
92 G3A 0.591837 0.811765
93 5N5 0.589041 0.7375
94 4UU 0.585859 0.809524
95 G5P 0.585859 0.811765
96 AFH 0.585859 0.802326
97 5CD 0.581081 0.725
98 A4D 0.581081 0.759494
99 6V0 0.578431 0.811765
100 NAI 0.578431 0.821429
101 ADP BMA 0.574468 0.829268
102 LAQ 0.574257 0.804598
103 DTA 0.571429 0.753086
104 3DH 0.56962 0.719512
105 YLP 0.568627 0.747253
106 48N 0.568627 0.811765
107 A A 0.568421 0.82716
108 G5A 0.568182 0.894118
109 YLC 0.567308 0.764045
110 AP0 0.567308 0.811765
111 MTA 0.564103 0.719512
112 2A5 0.563218 0.807229
113 TXD 0.563107 0.821429
114 UP5 0.563107 0.831325
115 NAX 0.563107 0.793103
116 NXX 0.563107 0.841463
117 DND 0.563107 0.841463
118 4UW 0.563107 0.781609
119 JB6 0.5625 0.843373
120 A3P 0.559524 0.848101
121 EP4 0.558442 0.682353
122 TYM 0.557692 0.819277
123 TXE 0.557692 0.821429
124 OMR 0.557692 0.775281
125 7D5 0.556962 0.771084
126 PAP 0.556818 0.860759
127 ATR 0.556818 0.848101
128 MYR AMP 0.556701 0.744444
129 IOT 0.556604 0.73913
130 UPA 0.552381 0.821429
131 4TC 0.552381 0.811765
132 YLB 0.552381 0.747253
133 T5A 0.551402 0.766667
134 139 0.551402 0.793103
135 M2T 0.551282 0.705882
136 A5A 0.549451 0.926829
137 TAD 0.54902 0.823529
138 TSB 0.548387 0.939024
139 7D3 0.547619 0.795181
140 A4P 0.54717 0.75
141 ATP A A A 0.545455 0.8375
142 SSA 0.543478 0.916667
143 3AM 0.54321 0.8125
144 A2P 0.541176 0.835443
145 7D4 0.54023 0.795181
146 ITT 0.54023 0.825
147 TYR AMP 0.54 0.797619
148 VMS 0.537634 0.904762
149 52H 0.537634 0.894118
150 A2R 0.537634 0.8625
151 54H 0.537634 0.904762
152 ADJ 0.537037 0.775281
153 YLA 0.537037 0.747253
154 ZAS 0.536585 0.694118
155 J7C 0.535714 0.678161
156 AMP DBH 0.534653 0.807229
157 5X8 0.534091 0.710843
158 AYB 0.53211 0.73913
159 CNA 0.53211 0.841463
160 53H 0.531915 0.894118
161 5CA 0.531915 0.916667
162 6RE 0.53012 0.670455
163 AHZ 0.528846 0.764045
164 M24 0.526316 0.772727
165 7MD 0.524272 0.784091
166 AR6 AR6 0.524272 0.82716
167 DSH 0.52381 0.678161
168 NAD 0.522523 0.839506
169 BTX 0.522523 0.766667
170 COD 0.522523 0.76087
171 6AD 0.521739 0.823529
172 LSS 0.520833 0.873563
173 DSZ 0.520833 0.916667
174 NSS 0.520833 0.916667
175 GSU 0.520408 0.894118
176 P5A 0.520408 0.853933
177 KAA 0.520408 0.863636
178 BT5 0.517857 0.758242
179 A3N 0.517647 0.710843
180 IMO 0.517647 0.8125
181 NVA LMS 0.515464 0.873563
182 ARG AMP 0.514286 0.736264
183 A3D 0.513274 0.829268
184 2AM 0.512195 0.825
185 GJV 0.511628 0.662921
186 S4M 0.511628 0.645161
187 V3L 0.51087 0.85
188 LEU LMS 0.510204 0.873563
189 LPA AMP 0.509434 0.784091
190 MAO 0.505747 0.692308
191 LA8 ALF 3PG 0.5 0.761364
192 ALF ADP 3PG 0.5 0.761364
193 AF3 ADP 3PG 0.5 0.761364
194 YLY 0.5 0.73913
195 SFG 0.5 0.678571
196 SAH 0.5 0.694118
197 NAE 0.495726 0.809524
198 7MC 0.495413 0.766667
199 YSA 0.495146 0.894118
200 NA7 0.494949 0.841463
201 AVV 0.494845 0.811765
202 A7D 0.494382 0.722892
203 OVE 0.494118 0.839506
204 5AD 0.493333 0.670886
205 EAD 0.491667 0.793103
206 NAQ 0.491525 0.790698
207 DZD 0.491228 0.802326
208 AAT 0.489362 0.662921
209 SA8 0.48913 0.644444
210 A5D 0.48913 0.753086
211 PGS 0.488889 0.821429
212 71V 0.488636 0.821429
213 N0B 0.487395 0.747253
214 ZID 0.487395 0.829268
215 ARU 0.484848 0.761364
216 AV2 0.484211 0.804878
217 SAI 0.483871 0.666667
218 DAT 0.483516 0.795181
219 NAJ PZO 0.482759 0.770115
220 4TA 0.482456 0.736264
221 3AT 0.478723 0.85
222 DTP 0.478723 0.795181
223 P1H 0.475806 0.775281
224 NAD IBO 0.473684 0.788235
225 EEM 0.473684 0.630435
226 WSA 0.472727 0.904762
227 MHZ 0.472527 0.638298
228 7C5 0.471698 0.72093
229 D5M 0.471264 0.771084
230 DA 0.471264 0.771084
231 A3G 0.471264 0.722892
232 G A A A 0.469565 0.770115
233 Y3J 0.468354 0.654321
234 6C6 0.468085 0.776471
235 7D7 0.467532 0.670732
236 NDE 0.464 0.819277
237 SMM 0.463918 0.663043
238 S7M 0.463918 0.666667
239 6IA 0.463158 0.741573
240 SAM 0.463158 0.666667
241 4YB 0.462963 0.873563
242 SFD 0.461538 0.83871
243 NJP 0.46087 0.831325
244 6FA 0.457364 0.766667
245 0WD 0.456897 0.811765
246 FB0 0.456693 0.71875
247 NDC 0.456693 0.790698
248 NEC 0.454545 0.674699
249 NAJ PYZ 0.454545 0.772727
250 2SA 0.453608 0.819277
251 U A G G 0.452991 0.77907
252 A6D 0.45098 0.696629
253 PO4 PO4 A A A A PO4 0.45098 0.8125
254 A A A 0.45098 0.817073
255 FDA 0.449612 0.741935
256 AAM 0.449438 0.848101
257 DDS 0.447917 0.771084
258 62F 0.447761 0.784091
259 Z5A 0.447154 0.712766
260 C2R 0.447059 0.792683
261 AMZ 0.447059 0.802469
262 649 0.446429 0.853933
263 7DD 0.445652 0.860759
264 A3S 0.445652 0.731707
265 0UM 0.445545 0.637363
266 NDP 0.443478 0.811765
267 RGT 0.443396 0.841463
268 101 0.443182 0.771084
269 N6P 0.441176 0.8
270 62X 0.441176 0.610526
271 FAS 0.439394 0.775281
272 FAD 0.439394 0.775281
273 AMP NAD 0.439024 0.797619
274 AIR 0.439024 0.7875
275 KB1 0.438095 0.637363
276 128 0.4375 0.691489
277 K15 0.436893 0.623656
278 NIA 0.436782 0.727273
279 A3T 0.43617 0.740741
280 ODP 0.435897 0.802326
281 6K6 0.435644 0.814815
282 S8M 0.435644 0.709302
283 GEK 0.435644 0.709302
284 V1N 0.435185 0.82716
285 7RA 0.433333 0.8375
286 SLU 0.433333 0.883721
287 AS 0.433333 0.797619
288 7DT 0.431579 0.860759
289 NPW 0.431034 0.784091
290 RFL 0.430657 0.75
291 8BR 0.428571 0.797619
292 SXZ 0.428571 0.666667
293 NZQ 0.42735 0.802326
294 TXP 0.42735 0.811765
295 3AD 0.426829 0.725
296 FNK 0.426471 0.71875
297 APU 0.426087 0.788235
298 A U 0.426087 0.788235
299 PLP AAD 0.425 0.715789
300 TM1 0.424528 0.688172
301 FAY 0.423358 0.784091
302 VRT 0.42268 0.697674
303 SO8 0.42268 0.714286
304 7RP 0.422222 0.810127
305 26A 0.421687 0.690476
306 2VA 0.421053 0.722892
307 12D 0.419643 0.698925
308 SP1 0.41573 0.82716
309 QQY 0.41573 0.780488
310 RP1 0.41573 0.82716
311 ACK 0.41573 0.775
312 PUA 0.414634 0.781609
313 TAP 0.412698 0.843373
314 CC5 0.4125 0.734177
315 NAD BBN 0.411765 0.766667
316 3L1 0.409639 0.698795
317 3D1 0.409639 0.698795
318 CMP 0.408602 0.810127
319 2BA 0.408602 0.822785
320 XNP 0.408333 0.772727
321 GP3 0.408163 0.811765
322 ETB 0.406504 0.741935
323 DCA 0.406504 0.734043
324 GMV 0.405941 0.790698
325 NAD CJ3 0.405797 0.78022
326 2FA 0.404762 0.73494
327 NAP 0.404762 0.829268
328 QQX 0.404494 0.792683
329 GDP 0.40404 0.809524
330 P5F 0.402778 0.734043
331 JLN 0.402174 0.780488
332 FAI 0.402174 0.802469
333 P2P 0.402174 0.790123
334 RMB 0.402174 0.7625
335 GCP 0.401961 0.790698
336 ANZ 0.401786 0.707865
337 1DG 0.401575 0.811765
338 DG1 0.401575 0.811765
339 0T1 0.4 0.734043
340 U G A 0.4 0.744444
341 COA 0.4 0.752688
342 GNH 0.4 0.8
343 103 0.4 0.73494
344 5F1 0.4 0.642857
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1M7G; Ligand: ADX; Similar sites found: 511
This union binding pocket(no: 1) in the query (biounit: 1m7g.bio1) has 46 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 3DOE GTP 0.00006804 0.49207 None
2 1A4R GNH 0.000254 0.48568 None
3 1A4R GDP 0.0003246 0.47606 None
4 3DEF GDP 0.0006226 0.47239 None
5 1Z2A GDP 0.0002081 0.4714 None
6 1M7B GTP 0.0004669 0.46458 None
7 3RWO GDP 0.001107 0.43359 None
8 1MH1 GNP 0.001821 0.42162 None
9 3SBD GNP 0.002735 0.41746 None
10 3BRN SRO 0.04346 0.40281 None
11 2EW1 GNP 0.0005319 0.40033 None
12 4RZ3 ADP 0.003337 0.43409 0.947867
13 1S8F GDP 0.0005474 0.43932 1.12994
14 1U8Z GDP 0.000859 0.44518 1.19048
15 1OXV ANP 0.00001304 0.58066 1.4218
16 4LPS GDP 0.00007398 0.52807 1.4218
17 4LHW GNP 0.0008247 0.43884 1.72414
18 1I4D GDP 0.0001725 0.5227 1.89573
19 4NON GDP 0.0005635 0.43882 1.89573
20 4OHY ANP 0.006043 0.40613 1.89573
21 5WRI A3P 0.009866 0.40285 1.89573
22 5WRJ A3P 0.009268 0.40112 1.89573
23 3PQC GDP 0.0001543 0.50648 2.05128
24 2GJ8 ALF GDP 0.000984 0.4324 2.32558
25 1Z08 GNP 0.002081 0.42881 2.35294
26 2CBZ ATP 0.00000301 0.64865 2.36967
27 4AG5 ADP 0.0000491 0.56486 2.36967
28 4YDS ATP 0.00007736 0.54819 2.36967
29 2HF9 GSP 0.00006253 0.51374 2.36967
30 5GVR LMR 0.0003877 0.51088 2.36967
31 1WDT GTP 0.0002331 0.48256 2.36967
32 4KBF AMP 0.002548 0.46226 2.36967
33 4MKG AP5 0.0001538 0.46209 2.36967
34 3TMK T5A 0.0002018 0.45295 2.36967
35 2WKQ GTP 0.001398 0.43617 2.36967
36 5K5Z ANP 0.002903 0.41946 2.36967
37 2BEK ATP 0.00427 0.41868 2.36967
38 3BER AMP 0.01502 0.41817 2.36967
39 3ZQ6 ADP ALF 0.003532 0.41001 2.36967
40 2Z5F A3P 0.009119 0.40738 2.36967
41 1E96 GTP 0.002576 0.41853 2.46305
42 2W58 ADP 0.000007105 0.62265 2.47525
43 1QF9 ADP 0.0001204 0.42896 2.57732
44 1QF9 C5P 0.0001204 0.42896 2.57732
45 1QF9 ALF 0.0001204 0.42896 2.57732
46 3H86 AP5 0.0003484 0.44173 2.60417
47 3E5H GNP 0.002459 0.41936 2.80899
48 5M04 GDP 0.000002914 0.61428 2.8436
49 1SKQ GDP 0.000006959 0.59474 2.8436
50 2QN6 GDP 0.00000798 0.59167 2.8436
51 2RCN GDP 0.000009179 0.58037 2.8436
52 3DC4 ADP 0.000028 0.57158 2.8436
53 2GDJ ANP 0.000026 0.55757 2.8436
54 1V8K ANP 0.00006251 0.53837 2.8436
55 2IYL GDP 0.0002011 0.51278 2.8436
56 1G6O ADP 0.0001756 0.50378 2.8436
57 2PL3 ADP 0.0005228 0.49783 2.8436
58 4RD0 GDP 0.0001309 0.4844 2.8436
59 1ION ADP 0.0006111 0.4777 2.8436
60 4H1V GNP 0.001325 0.4526 2.8436
61 4WEI GLC GAL 0.005044 0.45243 2.8436
62 1FNN ADP 0.001312 0.44866 2.8436
63 2CHG ANP 0.00269 0.43841 2.8436
64 3FYH ADP 0.001172 0.43594 2.8436
65 2ORV 4TA 0.001871 0.42423 2.8436
66 3GD8 GOL 0.0397 0.40613 2.8436
67 4XFR CIT 0.04771 0.401 2.8436
68 4WGF HX2 0.04545 0.4063 2.92683
69 1Z0J GTP 0.0007179 0.43792 2.94118
70 4V0K GDP 0.0001784 0.4701 2.95858
71 1YVD GNP 0.0006271 0.44372 2.95858
72 3RAB GNP 0.000367 0.41428 2.95858
73 3T12 GDP ALF 0.0001048 0.48859 3.0303
74 3T1O GDP 0.00003188 0.40139 3.0303
75 1W4R TTP 0.0004767 0.4417 3.07692
76 4DSU GDP 0.001127 0.43003 3.1746
77 1T5C ADP 0.0000007522 0.68065 3.31754
78 4ZNL BEF ADP 0.00003492 0.54413 3.31754
79 1YRB GDP 0.00003585 0.53078 3.31754
80 1G41 ADP 0.0006405 0.47672 3.31754
81 2QZ4 ADP 0.0008561 0.47065 3.31754
82 3TBK ANP 0.002557 0.46765 3.31754
83 4PJ3 ANP 0.001253 0.45808 3.31754
84 2IXE ATP 0.001733 0.4357 3.31754
85 4GOX A3P 0.001809 0.4314 3.31754
86 4NE2 ADP 0.0004002 0.4207 3.31754
87 3FB4 AP5 0.000166 0.41395 3.31754
88 4NE2 SH2 0.0004704 0.40977 3.31754
89 1RRC ADP 0.0000003692 0.40167 3.31754
90 4U5X GNP 0.000578 0.46474 3.37079
91 2RGX AP5 0.0002098 0.40289 3.39806
92 1UKZ ADP 0.0001625 0.45289 3.44828
93 4QM7 GTP 0.0000008888 0.63149 3.50877
94 5XCO GDP 0.0001527 0.50114 3.50877
95 4K81 GTP 0.001078 0.42766 3.50877
96 4BAS GNP 0.00006751 0.42346 3.51759
97 4WOP CTP 0.001358 0.44406 3.55556
98 1BO4 COA 0.01097 0.4251 3.57143
99 1NVU GTP 0.001466 0.42542 3.61446
100 1NVV GNP 0.001592 0.42398 3.61446
101 5NUL FMN 0.01161 0.40904 3.62319
102 2XT3 ADP 0.000006606 0.61983 3.79147
103 3WY9 GDP 0.000008631 0.58991 3.79147
104 3WYA GDP 0.00001223 0.57409 3.79147
105 1G3Q ADP 0.0002976 0.49831 3.79147
106 5LB3 ADP 0.0006399 0.49329 3.79147
107 2C77 GNP 0.0001357 0.48834 3.79147
108 2OBM ADP 0.002018 0.48121 3.79147
109 2XAU ADP 0.0006203 0.47739 3.79147
110 2C78 GNP 0.0002267 0.47405 3.79147
111 1OYY AGS 0.002245 0.45993 3.79147
112 2XTZ GSP 0.0005267 0.44683 3.79147
113 1D2N ANP 0.00458 0.42066 3.79147
114 1S3G AP5 0.0001183 0.41664 3.79147
115 1W5T ANP 0.006624 0.41355 3.79147
116 1AKY AP5 0.0003446 0.41077 3.79147
117 1W5T ADP 0.01257 0.40744 3.79147
118 3BFX A3P 0.01089 0.40706 3.79147
119 3WXM GTP 0.0006844 0.40495 3.79147
120 1WF3 GNP 0.001263 0.40032 3.79147
121 1HTW ADP 0.00001179 0.40833 3.79747
122 2VOH CIT 0.0398 0.40782 3.82166
123 1MR3 G3D 0.00001088 0.40949 3.8674
124 1Z0F GDP 0.00002263 0.55341 3.91061
125 1KAO GDP 0.0002844 0.48341 4.19162
126 2WJG GDP 0.00002411 0.55923 4.25532
127 4DKX GDP 0.00001825 0.56532 4.2654
128 5TSH ANP 0.00004648 0.54485 4.2654
129 5TSH ADP 0.0001234 0.54114 4.2654
130 3A1S GDP 0.0003919 0.49242 4.2654
131 5JCP GDP ALF 0.000231 0.48758 4.2654
132 1FP6 ADP 0.0003785 0.48258 4.2654
133 4QOS ADP 0.0009809 0.46781 4.2654
134 3B7G ANP 0.001573 0.46268 4.2654
135 2C04 GCP 0.0009763 0.45871 4.2654
136 5VGR GDP 0.001525 0.44979 4.2654
137 4XTR ADP 0.001827 0.44216 4.2654
138 1IN4 ADP 0.002246 0.43811 4.2654
139 4WZA ACP 0.002807 0.42903 4.2654
140 4WZA ADP 0.002954 0.42812 4.2654
141 1H65 GDP 0.002759 0.42693 4.2654
142 4XTR ATP 0.002836 0.42308 4.2654
143 4XVU ATP 0.003358 0.41995 4.2654
144 4NU0 AP5 0.0001745 0.41931 4.2654
145 2WOJ ADP ALF 0.004312 0.40651 4.2654
146 3ZS9 ADP ALF 0.004536 0.40563 4.2654
147 1D5C GDP 0.00009365 0.50566 4.32099
148 2FH5 GTP 0.00008259 0.49788 4.32432
149 2QQ0 THM 0.0008699 0.42527 4.34783
150 2QQ0 ANP 0.001217 0.41204 4.34783
151 2QQ0 TMP 0.00134 0.41049 4.34783
152 1ZC3 GNP 0.00175 0.42232 4.42478
153 3GFS FMN 0.02168 0.40287 4.5977
154 1TU3 GNP 0.0002515 0.46 4.67836
155 1G16 GDP 0.0004278 0.46208 4.70588
156 1R2Q GNP 0.0008132 0.40854 4.70588
157 1PUJ GNP 0.00002618 0.53721 4.73934
158 3BOS CDP 0.000123 0.52354 4.73934
159 5L3V GDP 0.00007361 0.52195 4.73934
160 4NCN GTP 0.0003022 0.4645 4.73934
161 4TMZ GSP 0.0003787 0.46033 4.73934
162 2GK6 ADP 0.004848 0.45289 4.73934
163 3DZD ADP 0.002031 0.44819 4.73934
164 3Q9L ATP 0.006743 0.41997 4.73934
165 3T34 GDP 0.003805 0.41764 4.73934
166 5I34 GDP 0.02075 0.40731 4.73934
167 3MJH GTP 0.0002232 0.46213 4.7619
168 5J6Y BGC 0.03516 0.41301 4.78723
169 5J6Y GLC 0.03516 0.41301 4.78723
170 2W2X GSP 0.0006671 0.45772 4.83871
171 1JJV ATP 0.00001131 0.59761 4.85437
172 3W5J GDP 0.0000008735 0.66436 4.90196
173 3QBT GNP 0.0005699 0.44543 5
174 1XTQ GDP 0.0002567 0.40966 5.08475
175 1Z83 AP5 0.0001292 0.44278 5.10204
176 1B7T ADP 0.000969 0.46806 5.12821
177 1KK8 BEF ADP 0.0008395 0.46174 5.19481
178 1GOJ ADP 0.000002165 0.65661 5.21327
179 4U00 ADP 0.000002041 0.65388 5.21327
180 2NCD ADP 0.000008609 0.60589 5.21327
181 2WIC GNP 0.000009282 0.57247 5.21327
182 1VHT BA3 0.00002859 0.54172 5.21327
183 2IS6 ADP 0.0001648 0.51714 5.21327
184 4HI0 GDP 0.00008821 0.49662 5.21327
185 5FTB ANP 0.000297 0.49279 5.21327
186 1TQ4 GDP 0.0001199 0.49072 5.21327
187 2DPY ADP 0.001013 0.48897 5.21327
188 5FHD ADP ALF 0.0005323 0.46206 5.21327
189 3RC3 ANP 0.003292 0.45651 5.21327
190 1Z6T ADP 0.001212 0.45438 5.21327
191 4YS0 ADP 0.002539 0.43957 5.21327
192 1QXA GLY GLY GLY 0.02764 0.41586 5.21327
193 5J1J ANP 0.002295 0.427 5.26316
194 1ZD9 GDP 0.00002598 0.52559 5.31915
195 1NF3 GNP 0.002193 0.4214 5.46875
196 2ZX2 RAM 0.01973 0.42582 5.64103
197 4KFU ACP 0.000002064 0.63891 5.6872
198 4LC1 GDP 0.00001306 0.57265 5.6872
199 1DAR GDP 0.00001871 0.56478 5.6872
200 3DKP ADP 0.0004635 0.49449 5.6872
201 5G41 AP5 0.00007648 0.48011 5.6872
202 4XGU ADP 0.000586 0.46894 5.6872
203 4ITR GDP 0.001339 0.44827 5.6872
204 2C9O ADP 0.002122 0.43547 5.6872
205 1E2K TMC 0.0003585 0.40478 5.6872
206 3R7F CP 0.0454 0.40285 5.6872
207 4R2I ANP 0.006608 0.44574 5.71429
208 1EK0 GNP 0.0003699 0.45313 5.88235
209 3Q85 GNP 0.00001251 0.57359 5.91716
210 1KSH GDP 0.000121 0.40955 5.92105
211 1HE1 GDP 0.0009871 0.45019 5.92593
212 5TB5 GDP 0.00005775 0.52703 6
213 5TAR GDP 0.0001106 0.50774 6.08108
214 3IIJ ADP 0.0000009368 0.63034 6.11111
215 4J0Q GDP 0.0000101 0.58638 6.16114
216 1JI0 ATP 0.00003237 0.56825 6.16114
217 4IHQ ADP 0.0002615 0.51338 6.16114
218 3BFV ADP 0.0002923 0.50459 6.16114
219 2EFE GNH 0.0002695 0.48952 6.16114
220 5N69 ADP 0.0003297 0.4854 6.16114
221 4V03 ADP 0.0005077 0.48158 6.16114
222 5IRN ADP 0.0004938 0.47713 6.16114
223 4LJ9 ACP 0.001228 0.47316 6.16114
224 3FWY ADP 0.001043 0.45739 6.16114
225 5I0H ADP BEF 0.0007627 0.45515 6.16114
226 4D81 ADP 0.001565 0.45353 6.16114
227 3EZ2 ADP 0.004373 0.45013 6.16114
228 4ZKD GDP 0.0005984 0.44111 6.16114
229 2B8T THM 0.001749 0.43552 6.16114
230 1NY5 ADP 0.003371 0.43388 6.16114
231 1L2T ATP 0.001792 0.42822 6.16114
232 1QHH ATP 0.00824 0.4272 6.16114
233 1QHG ATP 0.00797 0.42018 6.16114
234 5MVR ADP 0.00002054 0.56274 6.17284
235 2CJW GDP 0.00001092 0.57656 6.25
236 4BQS ADP 0.00001399 0.46651 6.25
237 4BQS K2Q 0.00001399 0.46651 6.25
238 2BCG GDP 0.0002461 0.48149 6.31068
239 2ZTS ADP 0.0003387 0.47522 6.3745
240 2ZEJ GDP 0.0006053 0.44091 6.52174
241 4DID GDP 0.0003085 0.49754 6.57895
242 4PPF FLC 0.0000002987 0.69581 6.63507
243 4TTQ ATP 0.000004027 0.59841 6.63507
244 4YMU ATP 0.00004588 0.55242 6.63507
245 2ZR9 DTP 0.00005526 0.54107 6.63507
246 4R98 GNH 0.0000854 0.53153 6.63507
247 4LYA ATP 0.0005494 0.48519 6.63507
248 2OM2 GDP 0.0002425 0.47718 6.63507
249 1Y3A GDP 0.0003648 0.46102 6.63507
250 1G4U GDP 0.0008488 0.4572 6.63507
251 4ZG4 VO4 ADP 0.000989 0.44257 6.63507
252 1SVK ALF GDP 0.0006175 0.42407 6.63507
253 1BH2 GSP 0.001328 0.4211 6.63507
254 3NKV GNP 0.000497 0.44786 6.85714
255 2C5L GTP 0.001136 0.42989 6.93642
256 1YZN GNP 0.0008912 0.43414 7.02703
257 1UAD GNP 0.001052 0.4345 7.07071
258 3B5J 12D 0.00003773 0.56472 7.109
259 1JWY ADP 0.0002454 0.50243 7.109
260 1D2E GDP 0.0001543 0.50093 7.109
261 1U0J ADP 0.001076 0.48163 7.109
262 4A4Z ANP 0.0009662 0.47841 7.109
263 1JWY GDP 0.0004864 0.47744 7.109
264 3KTA AP5 0.001021 0.46227 7.14286
265 4QRH 0O2 0.005452 0.4173 7.14286
266 1LFD GNP 0.00125 0.43142 7.18563
267 2JAQ DCP 0.002965 0.42225 7.31707
268 2X77 GDP 0.000008306 0.57484 7.40741
269 2G77 GDP 0.0001244 0.49997 7.57576
270 2G77 AF3 0.005141 0.45591 7.57576
271 2AWN ADP 0.000001006 0.67745 7.58294
272 2VF7 ADP 0.0001077 0.52004 7.58294
273 4IEE AGS 0.0003578 0.50634 7.58294
274 2NGR GDP 0.0002065 0.50612 7.58294
275 2FAH GDP 0.0004354 0.47971 7.58294
276 5HR5 ADP 0.0008378 0.46178 7.58294
277 1WQ1 GDP 0.001396 0.43619 7.58294
278 1WQ1 AF3 0.01375 0.43421 7.58294
279 3RLF ANP 0.00242 0.42601 7.58294
280 3M1I GTP 0.0003216 0.42056 7.58294
281 2NGR AF3 0.02023 0.41984 7.58294
282 4OI4 ATP 0.003948 0.41695 7.58294
283 3WYF GTP 0.0005743 0.41645 7.58294
284 5HR5 FLC 0.001561 0.40824 7.58294
285 5WDR GNP 0.001891 0.42097 7.60234
286 1GXU 2HP 0.002003 0.46411 7.69231
287 3REF GDP 0.001049 0.44517 7.73196
288 1GRN GDP 0.0008562 0.46134 7.88177
289 1GRN AF3 0.01955 0.42063 7.88177
290 5BQ5 ADP BEF 0.001015 0.4671 7.93651
291 5O2T GSP 0.001257 0.42811 8.02139
292 4P32 ADP 0.002056 0.43248 8.03213
293 5H67 ATP 0.01401 0.41578 8.0402
294 1G6H ADP 0.000002656 0.64985 8.05687
295 4WZ6 ATP 0.000013 0.59739 8.05687
296 4B47 GDP 0.00000735 0.59352 8.05687
297 4DCT GDP 0.00006187 0.5319 8.05687
298 1R6B ADP 0.0002775 0.4998 8.05687
299 4P4T GDP 0.0003206 0.4763 8.05687
300 5MZN ADP 0.003026 0.46376 8.05687
301 2XTN GTP 0.001083 0.4409 8.05687
302 1IHU AF3 0.001653 0.4366 8.05687
303 2QTV GNP 0.00006053 0.4363 8.05687
304 5M7P ADP 0.002715 0.43438 8.05687
305 1IHU ADP 0.002216 0.42764 8.05687
306 1LVG ADP 0.0000002896 0.42378 8.08081
307 1Y63 ADP 0.000000365 0.65098 8.15217
308 5UFQ GNP 0.000854 0.43822 8.19672
309 1RYH GNP 0.0001319 0.50977 8.37438
310 2Y8E GNP 0.0005223 0.44698 8.37989
311 2GCO GNP 0.000263 0.48498 8.45771
312 3LRE ADP 0.000006756 0.62227 8.53081
313 1SQ5 ADP 0.00004824 0.53722 8.53081
314 5XDR ADP 0.0005484 0.48523 8.53081
315 4MKF AP5 0.0001041 0.46997 8.53081
316 1NN5 ANP 0.00007314 0.46284 8.53081
317 3FKQ ATP 0.0009686 0.45887 8.53081
318 2FNA ADP 0.001586 0.43737 8.53081
319 2X7I CIT 0.02749 0.4048 8.53081
320 2QG6 NMN 0.0002387 0.45359 8.54271
321 2A5F GTP 0.00007955 0.48476 8.57143
322 1F6B GDP 0.000008372 0.57467 8.58586
323 4CVN ADP 0.00000005388 0.71551 8.75912
324 2FFQ GSP 0.0008191 0.40682 8.77193
325 1YZQ GNP 0.0006809 0.43885 8.82353
326 4KAX GTP 0.00005615 0.42591 8.87574
327 1Z06 GNP 0.0001899 0.46897 8.99471
328 1XMV ADP 0.00002891 0.54817 9.00474
329 2ZFI ADP 0.00006877 0.53628 9.00474
330 1XKV ATP 0.0002993 0.49263 9.00474
331 4M9Q GNP 0.0001062 0.48835 9.00474
332 5DI3 GNP 0.0001595 0.48068 9.00474
333 2OZE AGS 0.001853 0.44188 9.00474
334 3QKT ANP 0.007604 0.40194 9.00474
335 1J2J GTP 0.0000255 0.51022 9.03614
336 1O3Y GTP 0.00003287 0.50552 9.03614
337 2W83 GTP 0.00003872 0.50249 9.09091
338 5IRC GDP 0.001109 0.46524 9.13978
339 1S9D GDP 0.000008666 0.57394 9.14634
340 3LXR GDP 0.0002583 0.49571 9.18919
341 5HPY GDP 0.00046 0.47379 9.18919
342 4E03 ADP 0.0002096 0.5058 9.2233
343 3BC1 GNP 0.0004022 0.45163 9.23077
344 1KMQ GNP 0.001289 0.43767 9.23913
345 3N5C GDP 0.000002008 0.61365 9.25926
346 3CX8 GSP 0.001181 0.42309 9.35961
347 4XOI GTP 0.002073 0.42558 9.44444
348 3A4M ADP 0.00000008539 0.70491 9.47867
349 3MD0 GDP 0.000001976 0.62299 9.47867
350 1KK1 GNP 0.000006186 0.59738 9.47867
351 5IRR GSP 0.001461 0.43892 9.47867
352 1OS1 ATP 0.002266 0.41207 9.47867
353 3VMF GTP 0.0005339 0.40829 9.47867
354 3QXC ATP 0.003981 0.40791 9.47867
355 1OS1 PYR 0.002581 0.40718 9.47867
356 4XSH GSP 0.0003642 0.4738 9.49721
357 1TX4 ALF GDP 0.001777 0.43174 9.60452
358 4D0G GTP 0.0005001 0.45913 9.71429
359 2ODE ALF GDP 0.0009769 0.4263 9.92908
360 2A5J GDP 0.00004992 0.53008 9.94764
361 3CNL GNP 0.000003297 0.6115 9.95261
362 3NHB ADP 0.0000237 0.58275 9.95261
363 2D2F ADP 0.0001786 0.5403 9.95261
364 1P72 ADP 0.0007854 0.41979 9.95261
365 1M2O GNP 0.0001587 0.42696 10
366 1YZG GDP 0.000005663 0.58304 10.0559
367 1VG8 GNP 0.0005204 0.41358 10.1449
368 3AQ4 GDP 0.000004013 0.5904 10.3261
369 1Z0A GDP 0.00001965 0.54957 10.3448
370 5GOE GDP 0.00001628 0.5535 10.4265
371 5KSZ GCP 0.00027 0.49479 10.4265
372 3WYG GTP 0.0005725 0.43855 10.5263
373 2J59 GTP 0.00003436 0.5047 10.7143
374 3TK1 GDP 0.00001293 0.58937 10.9005
375 1G7S GDP 0.00002589 0.55053 10.9005
376 5GJC ATP 0.0001151 0.52499 10.9005
377 4HSE ADP 0.0003552 0.49452 10.9005
378 5L3W GDP 0.0002918 0.49316 10.9005
379 1G7C 5GP 0.001165 0.47431 10.9005
380 3VX3 ADP 0.00242 0.43664 10.9005
381 5L3S G 0.01373 0.43287 10.9005
382 5L3S GNP 0.00154 0.43098 10.9005
383 1ZIN AP5 0.0001053 0.41916 10.9005
384 1B0U ATP 0.0004599 0.47859 11.0687
385 3KUD GDP 0.0007291 0.45602 11.1111
386 5SZH GNP 0.0005803 0.44165 11.1111
387 1VG1 GDP 0.00001819 0.4015 11.3514
388 3GJ3 GDP 0.0000122 0.57414 11.3744
389 3GJ0 GDP 0.00001281 0.57307 11.3744
390 3GJ7 GDP 0.00001305 0.57267 11.3744
391 3GJ4 GDP 0.00001348 0.57195 11.3744
392 3GJ5 GDP 0.00001942 0.55668 11.3744
393 5BXQ GDP 0.00001971 0.55636 11.3744
394 3GJ8 GDP 0.00001974 0.55633 11.3744
395 3CH5 GDP 0.00002131 0.55469 11.3744
396 1NRJ GTP 0.0000653 0.5024 11.3744
397 2BIF SIN 0.0001301 0.46863 11.3744
398 2BIF ANP 0.0001847 0.45078 11.3744
399 1IBR GNP 0.0003532 0.45034 11.3744
400 4HAT GNP 0.0004871 0.44133 11.3744
401 2B8W ALF 5GP 0.002638 0.4212 11.3744
402 1F5N GNP 0.003719 0.40911 11.3744
403 1FQK GDP 0.0007145 0.44859 11.5646
404 1FQK ALF 0.03061 0.41282 11.5646
405 5KSP GDP 0.0001879 0.50814 11.5789
406 3U6B GDP 0.000006838 0.59513 11.8483
407 4G5G GDP 0.00001334 0.57218 11.8483
408 5JBQ GDP 0.00001469 0.57007 11.8483
409 1D8T GDP 0.00001698 0.5669 11.8483
410 3U6K GDP 0.0000228 0.56045 11.8483
411 2V7Q ATP 0.00005057 0.5298 11.8483
412 2BVN GNP 0.00003911 0.529 11.8483
413 4PC3 GDP 0.0001149 0.50696 11.8483
414 2V7Q ADP 0.001351 0.47106 11.8483
415 3TKL GTP 0.0003841 0.45619 11.8483
416 2CK3 ANP 0.001872 0.44168 11.8483
417 2CK3 ADP 0.002423 0.426 11.8483
418 4IDN GNP 0.004886 0.41614 11.8483
419 1U25 IHS 0.01591 0.41124 11.8483
420 3TNF GNP 0.001202 0.40523 11.8483
421 1GOT GDP 0.0004461 0.46129 12.0588
422 1GP2 GDP 0.0005348 0.45395 12.0588
423 2F9L GDP 0.0006201 0.45121 12.0603
424 4YLG GDP 0.00001791 0.53878 12.1387
425 5E5U MLI 0.01511 0.42087 12.3223
426 1ZCB GDP 0.0008047 0.40296 12.3223
427 1X1R GDP 0.002007 0.41992 12.3596
428 2BME GNP 0.0004643 0.44908 12.3656
429 5E95 GDP 0.0002905 0.48299 12.3711
430 1W7J ADP BEF 0.0005667 0.46961 12.5828
431 2OG2 MLI 0.00001696 0.59768 12.7962
432 2WHX ADP 0.00003655 0.57258 12.7962
433 1MKY GDP 0.00001557 0.56881 12.7962
434 3B9Q MLI 0.0001016 0.5564 12.7962
435 2JLR ANP 0.0004909 0.47725 12.7962
436 5L3R GCP 0.001484 0.43165 12.7962
437 1RE0 GDP 0.000001935 0.40934 12.7962
438 1SVI GDP 0.00001959 0.57152 12.8205
439 5J1S ATP 0.0007631 0.44372 13.0081
440 1OIX GDP 0.0006988 0.44179 13.089
441 1OIV GDP 0.0004636 0.41203 13.089
442 5FG3 GDP 0.000005483 0.60009 13.2701
443 3E70 GDP 0.0001058 0.52041 13.2701
444 1YTM ATP 0.0001148 0.49155 13.2701
445 1Z0K GTP 0.0002168 0.47064 13.3721
446 5KDO GDP 0.0002132 0.47965 13.5135
447 1WA5 GTP 0.001106 0.41846 13.6364
448 1JJ7 ADP 0.000001274 0.67199 13.7441
449 5UWH GNP 0.0003601 0.45 13.7441
450 5UWI GNP 0.0003621 0.4499 13.7441
451 5UWJ GNP 0.0003696 0.44954 13.7441
452 5UWU GNP 0.0003722 0.44942 13.7441
453 5DIF GNP 0.0003778 0.44916 13.7441
454 5DHF GNP 0.00039 0.4486 13.7441
455 5UWQ GNP 0.0004025 0.44805 13.7441
456 5UWO GNP 0.0004098 0.44773 13.7441
457 5UWW GNP 0.000425 0.4471 13.7441
458 5DI9 GNP 0.0005028 0.44078 13.7441
459 5UWP GNP 0.0005038 0.44075 13.7441
460 5UWS GNP 0.0005667 0.43872 13.7441
461 5UWT GNP 0.0003877 0.4179 13.7441
462 4GBM A3P 0.005949 0.40935 13.7441
463 5JCZ GDP 0.0001631 0.48956 13.9665
464 4LX0 BEF GDP 0.0007154 0.40897 14.1243
465 1K6M AGS 0.001624 0.4334 14.218
466 1ZUI SKM 0.00007922 0.44113 14.2857
467 2D7C GTP 0.0005897 0.44482 14.3713
468 1ZJ6 G3D 0.000004128 0.58979 14.4385
469 4C4P GNP 0.0008936 0.40553 14.4509
470 2HV8 GTP 0.0006314 0.40641 14.5349
471 3GJX GTP 0.0003638 0.41894 14.6919
472 5UQW GDP 0.0007614 0.44377 14.8148
473 5H56 ADP 0.000028 0.47419 14.8718
474 5H56 TYD 0.000028 0.47419 14.8718
475 2WMO GTP 0.0001276 0.51045 15.1659
476 1XP8 AGS 0.00005147 0.54984 15.6398
477 5LTJ ADP 0.00009084 0.52368 15.6398
478 5LTJ BEF 0.001161 0.49941 15.6398
479 2VB6 ADP BEF 0.0004426 0.45745 16.1074
480 4R43 GDP 0.0003304 0.50191 16.1137
481 3X1Z GNP 0.002497 0.41321 16.1677
482 3FVQ ATP 0.001679 0.43997 16.5877
483 4KVG GTP 0.0009576 0.40024 16.6667
484 1GUA GNP 0.001948 0.42044 16.7665
485 3PCR GTP 0.0001018 0.48462 17.0616
486 1YQT ADP 0.00007457 0.55397 18.9573
487 3DDC GNP 0.00152 0.42478 19.6319
488 4PX9 ADP 0.000583 0.49538 19.9052
489 1UJ2 C5P 0.00001988 0.50069 20.3791
490 1UJ2 ADP 0.00002618 0.49587 20.3791
491 3ZIA ATP 0.00005898 0.53292 20.6349
492 3ZIA ADP 0.0001314 0.50422 20.6349
493 1TAD GDP 0.001287 0.42164 21.327
494 1TAD ALF 0.001287 0.42164 21.327
495 5CK5 GDP 0.000003184 0.61228 22.2749
496 1UPT GTP 0.00004252 0.50559 23.3918
497 4ZI2 GNP 0.00009122 0.49121 23.6842
498 4GOJ GNP 0.00009147 0.41894 23.8095
499 5EE5 GTP 0.0001268 0.485 24.5614
500 1R4A GNP 0.0001319 0.47559 24.8485
501 1FZQ GDP 0.000003887 0.59918 24.8619
502 4HDO GNP 0.002034 0.41968 26.5403
503 4HDQ GNP 0.003451 0.41042 26.5403
504 1CXZ GSP 0.0009116 0.44782 29.0698
505 5HCN GCP 0.00003452 0.54437 29.3839
506 1CS4 GSP 0.0008528 0.43169 31.2796
507 1AZT GSP 0.001106 0.4242 31.2796
508 1FQJ GDP 0.0005312 0.45407 33.3333
509 1FQJ ALF 0.02901 0.41409 33.3333
510 2YOH WMJ 0.0001703 0.43951 35.2381
511 1KO8 6PG 0.00005086 0.42335 44
Pocket No.: 2; Query (leader) PDB : 1M7G; Ligand: ADP; Similar sites found: 517
This union binding pocket(no: 2) in the query (biounit: 1m7g.bio1) has 29 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1A4R GNH 0.0002108 0.48615 None
2 3DOE GTP 0.00008718 0.48408 None
3 1A4R GDP 0.0002868 0.47528 None
4 3DEF GDP 0.0008678 0.46258 None
5 1Z2A GDP 0.0003019 0.46132 None
6 1M7B GTP 0.0004899 0.46054 None
7 3RWO GDP 0.001334 0.42732 None
8 1MH1 GNP 0.001658 0.42035 None
9 3SBD GNP 0.002742 0.41459 None
10 2EW1 GNP 0.0005929 0.40869 None
11 5LJI FMN 0.01398 0.40606 None
12 4RZ3 ADP 0.003169 0.43231 0.947867
13 1S8F GDP 0.000571 0.4355 1.12994
14 1U8Z GDP 0.001303 0.43451 1.19048
15 1OXV ANP 0.000009553 0.58386 1.4218
16 4LPS GDP 0.0000957 0.51918 1.4218
17 4LHW GNP 0.001049 0.43156 1.72414
18 1I4D GDP 0.0001179 0.52789 1.89573
19 4NON GDP 0.0005474 0.43622 1.89573
20 4OHY ANP 0.003951 0.41109 1.89573
21 3PQC GDP 0.000151 0.50361 2.05128
22 2GJ8 ALF GDP 0.001448 0.4227 2.32558
23 1Z08 GNP 0.002165 0.42521 2.35294
24 2CBZ ATP 0.000003781 0.637 2.36967
25 4AG5 ADP 0.00003188 0.57189 2.36967
26 4YDS ATP 0.00007251 0.54624 2.36967
27 5GVR LMR 0.0001855 0.53664 2.36967
28 2HF9 GSP 0.0001024 0.50049 2.36967
29 1WDT GTP 0.0002462 0.47825 2.36967
30 4MKG AP5 0.0002823 0.45833 2.36967
31 3TMK T5A 0.0002057 0.44937 2.36967
32 4KBF AMP 0.004608 0.4462 2.36967
33 2WKQ GTP 0.001337 0.43405 2.36967
34 3BER AMP 0.0155 0.41494 2.36967
35 5K5Z ANP 0.004415 0.40909 2.36967
36 2BEK ATP 0.009841 0.40028 2.36967
37 1E96 GTP 0.002422 0.41678 2.46305
38 2W58 ADP 0.000006058 0.62177 2.47525
39 1QF9 ADP 0.0001593 0.4183 2.57732
40 1QF9 C5P 0.0001593 0.4183 2.57732
41 1QF9 ALF 0.0001593 0.4183 2.57732
42 3H86 AP5 0.0001975 0.45784 2.60417
43 3E5H GNP 0.003419 0.41068 2.80899
44 5M04 GDP 0.000005614 0.5957 2.8436
45 2QN6 GDP 0.00001235 0.57814 2.8436
46 1SKQ GDP 0.00001432 0.57485 2.8436
47 3DC4 ADP 0.00002205 0.57344 2.8436
48 2RCN GDP 0.00001689 0.56334 2.8436
49 2GDJ ANP 0.00002693 0.5532 2.8436
50 1V8K ANP 0.00006055 0.5356 2.8436
51 1G6O ADP 0.00005428 0.52484 2.8436
52 2PL3 ADP 0.0004686 0.49716 2.8436
53 2IYL GDP 0.0005364 0.48819 2.8436
54 4RD0 GDP 0.0002324 0.47034 2.8436
55 4WEI GLC GAL 0.00356 0.46118 2.8436
56 1ION ADP 0.001207 0.4605 2.8436
57 1FNN ADP 0.001529 0.44272 2.8436
58 4H1V GNP 0.001953 0.44193 2.8436
59 2CHG ANP 0.002631 0.43601 2.8436
60 3FYH ADP 0.0009935 0.43593 2.8436
61 2ORV 4TA 0.001449 0.42585 2.8436
62 4XFR CIT 0.04364 0.40058 2.8436
63 3GD8 GOL 0.04382 0.40049 2.8436
64 4WGF HX2 0.03793 0.40822 2.92683
65 1Z0J GTP 0.0009733 0.42959 2.94118
66 4V0K GDP 0.0002578 0.4602 2.95858
67 1YVD GNP 0.0007939 0.43648 2.95858
68 3RAB GNP 0.0004599 0.42179 2.95858
69 3T12 GDP ALF 0.0001748 0.47566 3.0303
70 3T1O GDP 0.00006423 0.40373 3.0303
71 1W4R TTP 0.0003491 0.44388 3.07692
72 4DSU GDP 0.001406 0.42321 3.1746
73 1T5C ADP 0.0000008953 0.67107 3.31754
74 4ZNL BEF ADP 0.00007124 0.52544 3.31754
75 1YRB GDP 0.00005994 0.5168 3.31754
76 1G41 ADP 0.0008427 0.46795 3.31754
77 2QZ4 ADP 0.001037 0.46365 3.31754
78 3TBK ANP 0.002897 0.46195 3.31754
79 4NE2 ADP 0.0000794 0.43668 3.31754
80 2IXE ATP 0.001659 0.43361 3.31754
81 1RRC ADP 0.00000006096 0.43038 3.31754
82 4NE2 SH2 0.00009408 0.42461 3.31754
83 4PJ3 ANP 0.006152 0.42279 3.31754
84 2ZE7 DST 0.001161 0.41273 3.31754
85 4GOX A3P 0.004298 0.41262 3.31754
86 1CR1 TTP 0.0002848 0.40827 3.31754
87 4TMK T5A 0.003621 0.40674 3.31754
88 2ZE7 AMP 0.001465 0.40475 3.31754
89 3FB4 AP5 0.0002253 0.4027 3.31754
90 4U5X GNP 0.0005154 0.46388 3.37079
91 1UKZ ADP 0.0001823 0.45775 3.44828
92 4QM7 GTP 0.0000008312 0.62878 3.50877
93 5XCO GDP 0.0002187 0.49054 3.50877
94 4K81 GTP 0.001218 0.42259 3.50877
95 4BAS GNP 0.0001052 0.42846 3.51759
96 4WOP CTP 0.004526 0.41814 3.55556
97 1BO4 COA 0.008634 0.42773 3.57143
98 1NVU GTP 0.001864 0.41832 3.61446
99 1NVV GNP 0.002067 0.41653 3.61446
100 2UZI GTP 0.001566 0.40289 3.61446
101 5NUL FMN 0.01151 0.40663 3.62319
102 2XT3 ADP 0.000004779 0.62353 3.79147
103 3WY9 GDP 0.00002259 0.5647 3.79147
104 3WYA GDP 0.00003266 0.54901 3.79147
105 5LB3 ADP 0.0006407 0.49019 3.79147
106 2XAU ADP