Receptor
PDB id Resolution Class Description Source Keywords
1N0U 2.12 Å NON-ENZYME: TRANSCRIPT_TRANSLATE CRYSTAL STRUCTURE OF YEAST ELONGATION FACTOR 2 IN COMPLEX WITH SORDARIN SACCHAROMYCES CEREVISIAE G-PROTEIN CIS-PROLINE TRANSLATION
Ref.: TWO CRYSTAL STRUCTURES DEMONSTRATE LARGE CONFORMATIONAL CHANGES IN THE EUKARYOTIC RIBOSOMAL TRANSLOCASE. NAT.STRUCT.MOL.BIOL. V. 10 379 2003
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
SO1 A:843;
Valid;
none;
submit data
494.618 C27 H42 O8 C[C@@...
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1N0U 2.12 Å NON-ENZYME: TRANSCRIPT_TRANSLATE CRYSTAL STRUCTURE OF YEAST ELONGATION FACTOR 2 IN COMPLEX WITH SORDARIN SACCHAROMYCES CEREVISIAE G-PROTEIN CIS-PROLINE TRANSLATION
Ref.: TWO CRYSTAL STRUCTURES DEMONSTRATE LARGE CONFORMATIONAL CHANGES IN THE EUKARYOTIC RIBOSOMAL TRANSLOCASE. NAT.STRUCT.MOL.BIOL. V. 10 379 2003
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 257 families.
1 1N0U - SO1 C27 H42 O8 C[C@@H]1CC....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 222 families.
1 1N0U - SO1 C27 H42 O8 C[C@@H]1CC....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 185 families.
1 1N0U - SO1 C27 H42 O8 C[C@@H]1CC....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: SO1; Similar ligands found: 1
No: Ligand ECFP6 Tc MDL keys Tc
1 SO1 1 1
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1N0U; Ligand: SO1; Similar sites found: 37
This union binding pocket(no: 1) in the query (biounit: 1n0u.bio1) has 21 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 3II1 BGC 0.00795 0.41459 1.30841
2 3GCM 5GP 0.03642 0.40499 1.63934
3 5CDH TLA 0.006118 0.42739 2.38095
4 4E28 9MZ 0.02938 0.4011 2.76923
5 1EXF GLY 0.01695 0.42488 2.89256
6 2ZX2 RAM 0.01418 0.41586 3.07692
7 1P9B HDA 0.02102 0.40593 3.61991
8 1SW1 PBE 0.007549 0.42939 3.63636
9 1U6R IOM 0.02561 0.40248 3.94737
10 3CL5 SIO 0.02096 0.40664 3.97878
11 4JOB TLA 0.02196 0.40419 4.0404
12 1QPR PHT 0.008267 0.42683 4.22535
13 5UE4 5XQ 0.008891 0.42351 4.23729
14 3OQJ 3CX 0.002919 0.43771 4.28016
15 1FHX 4IP 0.01356 0.41415 4.65116
16 3WRB GDE 0.006094 0.41792 5.26316
17 4MN7 SME 0.01074 0.41037 5.36913
18 4LSY FLC 0.004499 0.42303 5.49451
19 3MYZ TFX 0.02141 0.42254 6
20 1VC9 ATP 0.005844 0.41878 6.34921
21 3W68 PBU 0.02557 0.40634 6.39098
22 1AV5 AP2 0.01441 0.40026 7.14286
23 3N1S 5GP 0.01122 0.40541 7.56302
24 4DI8 0GY 0.008398 0.4074 7.92079
25 4DI8 0GZ 0.008398 0.4074 7.92079
26 5DEX 5E0 0.008417 0.40517 8.48057
27 1RDS GPC 0.004797 0.4186 8.57143
28 5H4I 7HQ 0.0338 0.40723 9.43396
29 4MPO AMP 0.01033 0.42665 9.80392
30 4YFY 0FX 0.01616 0.40587 10.2362
31 5C79 PBU 0.01384 0.41855 12
32 3SJK LYS PRO VAL LEU ARG THR ALA 0.02898 0.40059 12.6316
33 4CQK PIO 0.00354 0.44799 12.766
34 5FIT AP2 0.01204 0.40396 16.3265
35 1KTG AMP 0.006565 0.44283 18.1159
36 1VHZ APR 0.01908 0.40849 20.202
37 4YEF 4CQ 0.01343 0.43952 22.4719
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