Receptor
PDB id Resolution Class Description Source Keywords
1N2X 1.9 Å EC: 2.1.1.- CRYSTAL STRUCTURE ANALYSIS OF TM0872, A PUTATIVE SAM- DEPENDENT METHYLTRANSFERASE, COMPLEXED WITH SAM THERMOTOGA MARITIMA SAM-DEPENDENT METHYLTRANSFERASE FOLD PROTEIN-SAM METHYL DONOR COMPLEX STRUCTURAL GENOMICS PSI PROTEIN STRUCTURE INITIATIVE MIDWEST CENTER FOR STRUCTURAL GENOMICS MCSG
Ref.: CRYSTAL COMPLEXES OF A PREDICTED S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE REVEAL A TYPICAL ADOMET BINDING DOMAIN AND A SUBSTRATE RECOGNITION DOMAIN PROTEIN SCI. V. 12 1432 2003
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
SAM A:401;
B:402;
 Valid;
Valid;
 none;
none;
 submit data
398.437 C15 H22 N6 O5 S C[S@@...
SO4 A:500;
B:501;
 Invalid;
Invalid;
 none;
none;
 submit data
96.063 O4 S [O-]S...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1N2X 1.9 Å EC: 2.1.1.- CRYSTAL STRUCTURE ANALYSIS OF TM0872, A PUTATIVE SAM- DEPENDENT METHYLTRANSFERASE, COMPLEXED WITH SAM THERMOTOGA MARITIMA SAM-DEPENDENT METHYLTRANSFERASE FOLD PROTEIN-SAM METHYL DONOR COMPLEX STRUCTURAL GENOMICS PSI PROTEIN STRUCTURE INITIATIVE MIDWEST CENTER FOR STRUCTURAL GENOMICS MCSG
Ref.: CRYSTAL COMPLEXES OF A PREDICTED S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE REVEAL A TYPICAL ADOMET BINDING DOMAIN AND A SUBSTRATE RECOGNITION DOMAIN PROTEIN SCI. V. 12 1432 2003
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 57 families.
1 1M6Y - SAH C14 H20 N6 O5 S c1nc(c2c(n....
2 1N2X - SAM C15 H22 N6 O5 S C[S@@+](CC....
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 50 families.
1 1M6Y - SAH C14 H20 N6 O5 S c1nc(c2c(n....
2 1N2X - SAM C15 H22 N6 O5 S C[S@@+](CC....
50% Homology Family (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 3TKA - SAM C15 H22 N6 O5 S C[S@@+](CC....
2 1M6Y - SAH C14 H20 N6 O5 S c1nc(c2c(n....
3 1N2X - SAM C15 H22 N6 O5 S C[S@@+](CC....
4 1WG8 - SAM C15 H22 N6 O5 S C[S@@+](CC....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: SAM; Similar ligands found: 192
No: Ligand ECFP6 Tc MDL keys Tc
1 SAM 1 1
2 SMM 0.792683 0.96
3 S4M 0.6875 0.909091
4 S7M 0.670455 0.945946
5 M2T 0.636364 0.878378
6 GEK 0.612903 0.931507
7 SAI 0.571429 0.878378
8 XYA 0.565789 0.773333
9 ADN 0.565789 0.773333
10 RAB 0.565789 0.773333
11 5CD 0.564103 0.783784
12 EP4 0.5625 0.826667
13 SA8 0.56044 0.945205
14 SFG 0.555556 0.875
15 5X8 0.555556 0.888889
16 5N5 0.551282 0.773333
17 A4D 0.544304 0.797297
18 EEM 0.542553 0.945946
19 SAH 0.537634 0.916667
20 DTA 0.536585 0.789474
21 62X 0.535354 0.884615
22 MTA 0.53012 0.875
23 3DH 0.517647 0.849315
24 AMP MG 0.511364 0.710843
25 5AL 0.510417 0.743902
26 VMS 0.510204 0.673913
27 54H 0.510204 0.673913
28 0UM 0.51 0.857143
29 A 0.505747 0.707317
30 AMP 0.505747 0.707317
31 ABM 0.505618 0.753086
32 A5A 0.505155 0.688889
33 DAL AMP 0.50505 0.765432
34 NVA LMS 0.504951 0.725275
35 K15 0.5 0.883117
36 6RE 0.5 0.78481
37 5AD 0.5 0.75
38 SSA 0.5 0.684783
39 SON 0.5 0.746988
40 SRP 0.5 0.746988
41 LSS 0.49505 0.706522
42 CA0 0.494624 0.714286
43 A12 0.494505 0.705882
44 AP2 0.494505 0.705882
45 ME8 0.490385 0.841463
46 5CA 0.49 0.684783
47 TSB 0.49 0.681319
48 53H 0.49 0.666667
49 ACP 0.489362 0.694118
50 5AS 0.48913 0.648936
51 ADP 0.48913 0.690476
52 A2D 0.488889 0.690476
53 J7C 0.488889 0.772152
54 ZAS 0.488636 0.769231
55 8QN 0.485149 0.743902
56 GAP 0.484536 0.73494
57 AN2 0.483871 0.682353
58 A3S 0.483871 0.813333
59 A7D 0.483871 0.851351
60 GJV 0.483516 0.775
61 SRA 0.483146 0.694118
62 LAD 0.480769 0.752941
63 KAA 0.480769 0.698925
64 GSU 0.480769 0.722222
65 AMO 0.480392 0.746988
66 DSZ 0.480392 0.703297
67 52H 0.48 0.666667
68 ADP MG 0.478723 0.702381
69 M33 0.478723 0.722892
70 MAO 0.478261 0.82716
71 BA3 0.478261 0.690476
72 AOC 0.477778 0.776316
73 DSH 0.477778 0.842105
74 NEC 0.477778 0.75
75 SXZ 0.47619 0.894737
76 AHX 0.475728 0.701149
77 Y3J 0.47561 0.706667
78 G5A 0.474227 0.684783
79 A3T 0.473684 0.8
80 ADP BEF 0.473684 0.686047
81 BEF ADP 0.473684 0.686047
82 B4P 0.473118 0.690476
83 AP5 0.473118 0.690476
84 A3N 0.472527 0.766234
85 KB1 0.471698 0.833333
86 LEU LMS 0.471154 0.706522
87 APC 0.46875 0.705882
88 PRX 0.46875 0.73494
89 PAJ 0.466019 0.712644
90 4AD 0.466019 0.759036
91 RBY 0.463918 0.72619
92 ADP PO3 0.463918 0.728395
93 ADV 0.463918 0.72619
94 ADX 0.463158 0.666667
95 MHZ 0.463158 0.82716
96 AU1 0.463158 0.674419
97 YAP 0.462963 0.738095
98 TXA 0.462264 0.72619
99 NB8 0.462264 0.72093
100 A3G 0.461538 0.802632
101 VRT 0.459184 0.842105
102 ATP MG 0.459184 0.702381
103 YSA 0.458716 0.684783
104 XAH 0.458716 0.715909
105 50T 0.458333 0.682353
106 ATP 0.458333 0.690476
107 7D7 0.45679 0.723684
108 ANP MG 0.455446 0.678161
109 KH3 0.455357 0.871795
110 ACQ 0.454545 0.694118
111 AQP 0.453608 0.690476
112 5FA 0.453608 0.690476
113 AR6 0.453608 0.710843
114 APR 0.453608 0.710843
115 NSS 0.451923 0.703297
116 FA5 0.449541 0.746988
117 AGS 0.44898 0.678161
118 SAP 0.44898 0.678161
119 A5D 0.44898 0.789474
120 AD9 0.44898 0.674419
121 PTJ 0.448598 0.72093
122 YLB 0.448276 0.758621
123 YLP 0.447368 0.738636
124 D3Y 0.446602 0.792208
125 ADP ALF 0.445545 0.678161
126 ALF ADP 0.445545 0.678161
127 TYR AMP 0.445455 0.746988
128 MYR AMP 0.444444 0.776471
129 3AM 0.444444 0.674699
130 OAD 0.443396 0.73494
131 2VA 0.443299 0.779221
132 OOB 0.442308 0.722892
133 S8M 0.442308 0.831169
134 ADP VO4 0.441176 0.702381
135 VO4 ADP 0.441176 0.702381
136 ANP 0.44 0.674419
137 TAT 0.44 0.686047
138 WAQ 0.439252 0.75
139 ARG AMP 0.438596 0.727273
140 YLC 0.435897 0.755814
141 AAT 0.435644 0.797468
142 3OD 0.435185 0.73494
143 1ZZ 0.435185 0.755814
144 NVA 2AD 0.434343 0.815789
145 DLL 0.433962 0.722892
146 00A 0.433962 0.689655
147 7MD 0.433628 0.715909
148 ATF 0.431373 0.666667
149 SO8 0.43 0.792208
150 3UK 0.429907 0.714286
151 A6D 0.429907 0.72619
152 5SV 0.428571 0.741176
153 AMP DBH 0.428571 0.714286
154 WSA 0.42735 0.692308
155 TYM 0.42735 0.746988
156 9SN 0.427273 0.681818
157 AHZ 0.426087 0.755814
158 A A 0.425926 0.710843
159 3NZ 0.425926 0.807692
160 P5A 0.425926 0.691489
161 PR8 0.425926 0.744186
162 A1R 0.424528 0.709302
163 2A5 0.424242 0.674419
164 7MC 0.423729 0.719101
165 7D5 0.422222 0.658824
166 FYA 0.422018 0.722892
167 JB6 0.422018 0.709302
168 AYB 0.421488 0.75
169 PLP AAD 0.419355 0.764045
170 A22 0.419048 0.682353
171 MAP 0.419048 0.659091
172 2AM 0.417582 0.666667
173 TAD 0.417391 0.712644
174 A3P 0.416667 0.686747
175 ADP BMA 0.416667 0.714286
176 25A 0.415094 0.690476
177 YLA 0.413223 0.719101
178 ADQ 0.411215 0.694118
179 48N 0.410256 0.72093
180 0XU 0.41 0.824324
181 NAD IBO 0.406504 0.717647
182 7D3 0.40625 0.643678
183 PAP 0.405941 0.678571
184 OVE 0.404255 0.662791
185 4UV 0.403509 0.697674
186 ALF ADP 3PG 0.403361 0.712644
187 AF3 ADP 3PG 0.403361 0.712644
188 LA8 ALF 3PG 0.403361 0.712644
189 3AD 0.402299 0.783784
190 CMP 0.402062 0.691358
191 2BA 0.402062 0.682927
192 7C5 0.4 0.731707
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1N2X; Ligand: SAM; Similar sites found: 402
This union binding pocket(no: 1) in the query (biounit: 1n2x.bio2) has 25 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1PTR PRB 0.02818 0.40611 None
2 1TDF FAD 0.01617 0.40398 1.3289
3 1TDF NAP 0.03459 0.40253 1.3289
4 4RDH AMP 0.002558 0.4343 1.38889
5 4X9M FAD 0.009895 0.40811 1.43541
6 2EJU SAH 0.000006989 0.49464 1.66113
7 3VSE SAH 0.00002428 0.44906 1.66113
8 4HXY NDP 0.003976 0.41634 1.66113
9 2CDU FAD 0.005504 0.41503 1.66113
10 5BVA FAD 0.0123 0.40759 1.66113
11 1JJ7 ADP 0.01864 0.42306 1.92308
12 5ITV NAI 0.001707 0.43049 1.96078
13 5FJN FAD 0.004782 0.42382 1.97368
14 5FJN BE2 0.005525 0.42382 1.97368
15 3PT9 SAH 0.0000002088 0.55004 1.99336
16 2YX1 SFG 0.0000006081 0.50754 1.99336
17 1BZL FAD 0.001768 0.4739 1.99336
18 1LVL NAD 0.0005537 0.44722 1.99336
19 1MO9 KPC 0.005179 0.44557 1.99336
20 1MO9 FAD 0.005703 0.44306 1.99336
21 5T67 SAH 0.001854 0.43975 1.99336
22 5T67 JHZ 0.002453 0.43938 1.99336
23 3CGD NAD 0.01629 0.42108 1.99336
24 3CGD FAD 0.01629 0.42108 1.99336
25 3CGD COA 0.01629 0.42108 1.99336
26 4C3Y FAD 0.006067 0.41834 1.99336
27 3IHG FAD 0.003126 0.41673 1.99336
28 4D7E FAD 0.005629 0.41461 1.99336
29 4C3Y ANB 0.009362 0.41454 1.99336
30 4MO2 FDA 0.007403 0.41056 1.99336
31 3NUG NAD 0.003692 0.41641 2.02429
32 2AOT SAH 0.00006712 0.44382 2.05479
33 1JQD SAH 0.0005141 0.40896 2.05479
34 4YMH SAH 0.000447 0.43558 2.08333
35 3MBI HSX 0.003302 0.44741 2.09059
36 4U60 SIA GAL BGC NGA GAL 0.03333 0.40041 2.14286
37 5KVA SAM 0.000006487 0.51222 2.15827
38 1GXU 2HP 0.008745 0.42878 2.1978
39 3BGD SAH 0.00006273 0.47791 2.30769
40 3BGD PM6 0.0001294 0.4726 2.30769
41 4UCI SAM 0.0003111 0.43591 2.32558
42 4KRG SAH 0.0002456 0.42929 2.32558
43 4LWP SAH 0.0004594 0.42691 2.32558
44 4BV6 FAD 0.00449 0.42404 2.32558
45 1GOJ ADP 0.02525 0.41499 2.32558
46 2C7G FAD 0.01667 0.40935 2.32558
47 4FWE FAD 0.0108 0.40921 2.32558
48 2C7G ODP 0.01664 0.4087 2.32558
49 1REO FAD 0.01338 0.40144 2.32558
50 3FPF TNA 0.0000752 0.40215 2.34899
51 3FPF MTA 0.0000752 0.40215 2.34899
52 1I9G SAM 0.0000004843 0.55077 2.5
53 3C3Y SAH 0.00006053 0.4634 2.53165
54 1JG3 ADN 0.00005155 0.50088 2.55319
55 1AE1 NAP 0.006646 0.40811 2.5641
56 3RFV 15L 0.001879 0.42294 2.62172
57 3RFV NAI 0.003994 0.41089 2.62172
58 2GDZ NAD 0.005725 0.40711 2.62172
59 4PNE SAH 0.00009649 0.47033 2.65781
60 5DX1 SFG 0.000143 0.46723 2.65781
61 5DWQ SFG 0.0001758 0.4617 2.65781
62 5DX0 SFG 0.0002581 0.45672 2.65781
63 1FEC FAD 0.001603 0.44847 2.65781
64 5DXA SFG 0.0004633 0.44269 2.65781
65 5DX8 SFG 0.0004758 0.44223 2.65781
66 3UCL NAP 0.007977 0.43112 2.65781
67 3UCL CYH 0.007272 0.43112 2.65781
68 3UCL FAD 0.007272 0.43112 2.65781
69 1PN0 FAD 0.004377 0.43004 2.65781
70 1PN0 IPH 0.004574 0.43004 2.65781
71 1N4W FAD 0.004714 0.42504 2.65781
72 2V6G NAP 0.004396 0.41323 2.65781
73 5F8F SFG 0.0008711 0.4029 2.65781
74 3LRE ADP 0.03845 0.40273 2.65781
75 5JE8 NAD 0.002594 0.40098 2.65781
76 5G3U FDA 0.0132 0.40073 2.65781
77 1NFQ NAI 0.007638 0.40435 2.69231
78 1Q0S SAH 0.0000001199 0.59079 2.7027
79 2DPM SAM 0.0000008164 0.54806 2.8169
80 1C3V PDC 0.009564 0.43028 2.85714
81 4IF4 BEF 0.005393 0.43858 2.88462
82 5MPT SAH 0.000008916 0.4902 2.99003
83 3L9W AMP 0.00191 0.42844 2.99003
84 4RPL 3UC 0.008861 0.4284 2.99003
85 2DTX BMA 0.003253 0.4281 2.99003
86 3L9W GSH 0.001685 0.42791 2.99003
87 1UXG NAD 0.00328 0.42688 2.99003
88 4RPL FAD 0.0116 0.42116 2.99003
89 5BUK FAD 0.007872 0.41614 2.99003
90 4XQC NAD 0.01127 0.40839 2.99003
91 2XVE FAD 0.03005 0.40024 2.99003
92 3FZG SAM 0.001727 0.44214 3
93 1XHL NDP 0.005245 0.41126 3.0303
94 2ZL4 ALA ALA ALA ALA 0.03053 0.40563 3.06122
95 1GET FAD 0.01347 0.41939 3.11111
96 1GET NAP 0.01428 0.41939 3.11111
97 4N49 SAM 0.00009195 0.46275 3.32226
98 4TQG NDP 0.001962 0.42515 3.32226
99 4M52 FAD 0.005277 0.42195 3.32226
100 1FL2 FAD 0.005731 0.41744 3.32226
101 1I8T FAD 0.006615 0.41474 3.32226
102 1GPE FAD 0.00986 0.41269 3.32226
103 1GR0 NAD 0.008496 0.40473 3.32226
104 2YVF FAD 0.0261 0.40306 3.32226
105 2YVF NAD 0.02976 0.40105 3.32226
106 3WGT FAD 0.02064 0.40004 3.32226
107 3WGT QSC 0.02147 0.40004 3.32226
108 2JBH 5GP 0.01026 0.42251 3.55556
109 2GL0 ADN 0.02767 0.40466 3.59281
110 2BGM NAJ 0.00242 0.41842 3.59712
111 3CTY FAD 0.001491 0.44795 3.65448
112 4D04 FAD 0.008232 0.42736 3.65448
113 4D04 NAP 0.008232 0.42736 3.65448
114 1ELI PYC 0.003487 0.42573 3.65448
115 3GXO SAH 0.003998 0.4254 3.65448
116 2HQM FAD 0.005592 0.42084 3.65448
117 1SOW NAD 0.005424 0.41064 3.65448
118 2RGJ FAD 0.008717 0.40311 3.65448
119 3GWZ SAH 0.0008376 0.40278 3.65448
120 3LXD FAD 0.01139 0.40039 3.65448
121 4II2 ATP 0.0004755 0.43483 3.68098
122 4CS9 AMP 0.01641 0.4246 3.7037
123 2HNK SAH 0.0000653 0.46841 3.76569
124 4RL4 PPV 0.006123 0.43774 3.77358
125 2CBZ ATP 0.02535 0.41509 3.79747
126 4ZCC NAI 0.02316 0.40005 3.86905
127 4ZCC FAD 0.02316 0.40005 3.86905
128 1T57 FMN 0.004051 0.40115 3.8835
129 1I1N SAH 0.000007229 0.52446 3.9823
130 4J36 1HR 0.003401 0.43126 3.98671
131 4J36 FAD 0.002202 0.42845 3.98671
132 1Y8Q ATP 0.000886 0.42636 3.98671
133 2R4J 13P 0.006569 0.42543 3.98671
134 3UOY NAP 0.01818 0.41394 3.98671
135 3UOY FAD 0.01818 0.41394 3.98671
136 1XHC FAD 0.005875 0.41381 3.98671
137 4EIP FAD 0.01434 0.40631 3.98671
138 4EIP K2C 0.01434 0.40631 3.98671
139 4GUT FAD 0.01273 0.40861 4.03226
140 4HSU FAD 0.01821 0.40005 4.03226
141 5GM1 SAH 0.00008844 0.47186 4.0404
142 3LKZ SFG 0.000003577 0.51083 4.04984
143 3HVJ 705 0.00005039 0.50372 4.0724
144 2A14 SAH 0.002167 0.41195 4.18251
145 2PXX SAH 0.0001337 0.4493 4.18605
146 4DMG SAM 0.0000163 0.54854 4.31894
147 1NW5 SAM 0.000005899 0.5019 4.31894
148 2WPF FAD 0.002774 0.46405 4.31894
149 2WPF WPF 0.004058 0.45756 4.31894
150 3KLJ FAD 0.005058 0.41314 4.31894
151 3TKY SAH 0.001382 0.41199 4.31894
152 5KMS FAD 0.009704 0.40445 4.31894
153 3GMB FAD 0.01083 0.40023 4.31894
154 1KNR FAD 0.01505 0.40015 4.31894
155 2PX8 SAH 0.00001034 0.48569 4.46097
156 1IY8 NAD 0.004547 0.41261 4.49438
157 4BLW AMP 0.000004891 0.54244 4.49827
158 4BLW SAH 0.000003826 0.53383 4.49827
159 5JGL SAM 0.00005062 0.45294 4.49827
160 5JJR SAH 0.000002114 0.5618 4.65116
161 1V59 FAD 0.003661 0.43171 4.65116
162 1UWK NAD 0.00387 0.43064 4.65116
163 1X87 NAD 0.001203 0.42589 4.65116
164 2BRY FAD 0.002733 0.42448 4.65116
165 4TXI FAD 0.002697 0.42345 4.65116
166 3C6K SPD 0.003892 0.42149 4.65116
167 3C6K MTA 0.003892 0.42149 4.65116
168 1V59 NAD 0.0003465 0.41604 4.65116
169 1QO8 FAD 0.007294 0.41579 4.65116
170 4CNK FAD 0.007065 0.41248 4.65116
171 1OBB NAD 0.001991 0.41086 4.65116
172 4MIG G3F 0.01337 0.40926 4.65116
173 2E5V FAD 0.01135 0.40825 4.65116
174 5J60 FAD 0.01239 0.40385 4.65116
175 3FGZ BEF 0.004321 0.44164 4.6875
176 2BZG SAH 0.00001745 0.47732 4.74138
177 4YAG NAI 0.009758 0.41024 4.84429
178 5CUQ NSC 0.000006079 0.53503 4.86891
179 3LCV SAM 0.003059 0.40944 4.98221
180 5MW4 5JU 0.0000878 0.49724 4.98339
181 3QOX SAH 0.00002319 0.49543 4.98339
182 5JCA FAD 0.0014 0.44714 4.98339
183 5JCA NDP 0.003898 0.44155 4.98339
184 3ICT FAD 0.006085 0.41424 4.98339
185 3ICR FAD 0.007093 0.41137 4.98339
186 3ICS FAD 0.00789 0.41041 4.98339
187 2QQF A1R 0.003536 0.4101 4.98339
188 2OD9 A1R NCA 0.00585 0.40672 4.98339
189 3NT6 FAD 0.01175 0.40292 4.98339
190 4NTC FAD 0.01516 0.40094 4.98339
191 2ZIF SAM 0.0000006914 0.53774 5.05051
192 2WA2 SAM 0.000001858 0.50631 5.07246
193 3MB5 SAM 0.00000022 0.57745 5.09804
194 1XCL SAH 0.0005793 0.40439 5.10638
195 2JAH NDP 0.008099 0.40205 5.26316
196 2P41 SAH 0.000001771 0.56517 5.31561
197 4KRI SAH 0.00004321 0.47361 5.31561
198 3GD4 FAD 0.005316 0.4333 5.31561
199 3GD4 NAD 0.008267 0.4333 5.31561
200 5BR7 FAD 0.01217 0.41893 5.31561
201 5BR7 FLC 0.01445 0.4155 5.31561
202 2NVK FAD 0.007718 0.41377 5.31561
203 4TM3 FAD 0.02136 0.41126 5.31561
204 4YNU FAD 0.01023 0.41111 5.31561
205 4YNU LGC 0.01354 0.40902 5.31561
206 3OJO NAD 0.004575 0.40233 5.31561
207 2V3A FAD 0.01312 0.40084 5.31561
208 3EVF SAH 0.00001207 0.43183 5.41516
209 3EVF GTA 0.00001522 0.41598 5.41516
210 5XVK SAH 0.001608 0.42078 5.6338
211 1G55 SAH 0.0000000116 0.6526 5.64784
212 1U2Z SAH 0.00006224 0.47805 5.64784
213 2AWN ADP 0.00911 0.44551 5.64784
214 5KOK SAH 0.0003053 0.4374 5.64784
215 5KOK S9T 0.00209 0.43066 5.64784
216 5DNK SAH 0.0001521 0.4171 5.64784
217 4AP3 FAD 0.01306 0.41687 5.64784
218 4AP3 NAP 0.01306 0.41687 5.64784
219 2RGO FAD 0.006233 0.41379 5.64784
220 2RAB FAD 0.009119 0.41333 5.64784
221 2RAB NAD 0.0182 0.41333 5.64784
222 4YSX FAD 0.007569 0.41318 5.64784
223 4MOP 2H5 0.01479 0.40957 5.64784
224 5KOK R9T 0.008698 0.40315 5.64784
225 1G6H ADP 0.01851 0.42316 5.83658
226 1D4D FAD 0.003288 0.4319 5.98007
227 1P1C SAH 0.0001406 0.4637 6.03015
228 1I7E IBS 0.02756 0.4081 6.03774
229 1QAN SAH 0.0000008179 0.54805 6.14754
230 5N53 8NB 0.01635 0.4184 6.15385
231 1R18 SAH 0.000002632 0.52757 6.1674
232 5E1M PRO PRO LYS ARG ILE ALA 0.0003028 0.46632 6.22407
233 5E1M SAH 0.0003028 0.46632 6.22407
234 5HJM MTA 0.0001068 0.48206 6.31229
235 4OPC FDA 0.01249 0.43364 6.31229
236 4OPC PGT 0.01435 0.43364 6.31229
237 3ML1 MGD 0.02525 0.40896 6.31229
238 5ULP KB1 0.000002408 0.53766 6.34328
239 3G2O SAM 0.000006541 0.54026 6.35452
240 1MZV AMP 0.004572 0.43548 6.38298
241 2W58 ADP 0.01546 0.42637 6.43564
242 1XTT U5P 0.007257 0.41349 6.48148
243 5N5D SAM 0.0002635 0.43759 6.63717
244 5JCM NAD 0.009222 0.42699 6.64452
245 5JCM FAD 0.009222 0.42699 6.64452
246 5JCM ISD 0.009794 0.42699 6.64452
247 4D86 ADP 0.008247 0.40078 6.64452
248 3P2E SAH 0.0001655 0.46934 6.66667
249 1XTP SAI 0.0001059 0.44892 6.69291
250 2VDV SAM 0.00003751 0.52461 6.91057
251 5E8J SAH 0.0003451 0.47941 6.97674
252 1Q9I TEO 0.005461 0.43205 6.97674
253 5E9W SAH 0.0004184 0.41148 6.97674
254 4NTD FAD 0.008601 0.40879 6.97674
255 3A27 SAM 0.0000204 0.51856 6.98529
256 3T7S SAM 0.00002897 0.46756 7.08955
257 4NEC SAH 0.000318 0.47585 7.19697
258 1O97 FAD 0.004591 0.43472 7.19697
259 1O97 AMP 0.004591 0.43472 7.19697
260 4PIO SAH 0.0001803 0.47589 7.30897
261 4PIO AVI 0.0001966 0.47287 7.30897
262 3LAD FAD 0.003749 0.42844 7.30897
263 2IV2 MGD 0.004209 0.42003 7.30897
264 2DKH FAD 0.003537 0.41973 7.30897
265 2DKH 3HB 0.005074 0.41973 7.30897
266 1E1M FAD 0.01682 0.40777 7.30897
267 2XVF FAD 0.009933 0.40506 7.30897
268 4OBW SAM 0.0002078 0.47429 7.393
269 2YJP CYS 0.03303 0.40332 7.56014
270 1XDS SAM 0.0003337 0.48009 7.6412
271 4USR FAD 0.005693 0.41096 7.6412
272 3JSZ UPG 0.007182 0.40025 7.6412
273 1KPG SAH 0.00005511 0.48474 7.66551
274 1TPY SAH 0.00004449 0.4788 7.66551
275 1KPH SAH 0.00005085 0.47622 7.66551
276 1UAY ADN 0.002394 0.43993 7.85124
277 2ZFU SAH 0.0005177 0.43021 7.90698
278 1TE2 PGA 0.01454 0.42005 7.9646
279 3S1S SAH 0.00000213 0.53747 7.97342
280 5THY SAH 0.000004405 0.51263 7.97342
281 4DCM SAM 0.00009246 0.44161 7.97342
282 4AZW SAM 0.0003084 0.43571 7.97342
283 4AZT SAM 0.0002754 0.43286 7.97342
284 1QZZ SAM 0.0004146 0.40699 7.97342
285 3ELW SAM 0.00001337 0.41082 8
286 3ELW GP3 0.00001653 0.40427 8
287 1VBO MAN MAN MAN 0.02297 0.40521 8.05369
288 5GWX SAR 0.0005078 0.44637 8.09859
289 5GWX SAM 0.0005078 0.44637 8.09859
290 4R6W PC 0.005138 0.43022 8.13953
291 4R6W SAH 0.002108 0.42797 8.13953
292 1HGX 5GP 0.02192 0.40576 8.19672
293 3U31 NAD 0.000277 0.45575 8.27586
294 4BJZ P3A 0.0216 0.41213 8.30565
295 1V6A TRE 0.02513 0.40896 8.30565
296 2VVM FAD 0.01291 0.40307 8.30565
297 1L3I SAH 0.000001077 0.55652 8.33333
298 3AD8 NAD 0.00144 0.43755 8.37438
299 3AD8 PYC 0.02402 0.40774 8.37438
300 3AD8 FAD 0.02402 0.40774 8.37438
301 5E72 SAM 0.00000008159 0.58748 8.63787
302 5JWC FAD 0.003887 0.42037 8.63787
303 4USQ FAD 0.004303 0.41732 8.63787
304 4PPF FLC 0.03626 0.4074 8.63787
305 1DQN IMU 0.01303 0.41724 8.69565
306 3EVG SAH 0.000000684 0.5307 8.72727
307 3GCZ SAM 0.0000007382 0.52841 8.9701
308 5X62 SAH 0.0001267 0.44107 8.9701
309 1T26 NAI 0.005988 0.41954 8.9701
310 5FTW SAH 0.0003988 0.43612 8.98438
311 2GAG NAD 0.001235 0.44403 9.04762
312 2GAG FAD 0.0178 0.40131 9.04762
313 3DXY SAM 0.00004719 0.52638 9.17431
314 3MQ2 SAH 0.0008915 0.40891 9.17431
315 4JLS 3ZE 0.005585 0.44295 9.21053
316 1BC5 SAH 0.00327 0.40826 9.29368
317 5THZ SAH 0.000006926 0.51671 9.30233
318 5FA8 SAM 0.000006458 0.51794 9.31677
319 3VYW SAM 0.00000288 0.54352 9.63455
320 3LST SAH 0.0006555 0.46634 9.63455
321 2O07 MTA 0.001244 0.40802 9.63455
322 2PS1 ORO 0.007948 0.42812 9.73451
323 5MGZ SAH 0.00009301 0.4547 9.74576
324 3BBH SFG 0.01202 0.40001 9.7561
325 1KYQ NAD 0.001154 0.40702 9.85401
326 1ZEM NAD 0.004006 0.40938 9.92366
327 4RSL FAD 0.0006841 0.45383 9.96678
328 1UP7 NAD 0.001318 0.42769 9.96678
329 4A6D SAM 0.002109 0.42632 9.96678
330 2A92 NAI 0.004643 0.41349 9.96678
331 3GDN FAD 0.008282 0.41337 9.96678
332 3GDN HBX 0.01172 0.41337 9.96678
333 3F8D FAD 0.0215 0.41223 9.96678
334 4XUC 43G 0.0006131 0.4533 10.0917
335 4XUC SAM 0.0006131 0.4533 10.0917
336 1VE3 SAM 0.0006146 0.4536 10.1322
337 4YRY FAD 0.004225 0.42617 10.299
338 4YRY NAD 0.0109 0.41628 10.299
339 1V5F FAD 0.02093 0.40933 10.299
340 5LOG SAH 0.0003049 0.438 10.3004
341 3Q87 SAM 0.00007283 0.47528 10.4
342 2PT9 2MH 0.0006406 0.45249 10.5919
343 2PT9 S4M 0.0003454 0.45153 10.5919
344 4REP FAD 0.009744 0.40743 10.6312
345 3H2B SAH 0.00004268 0.46901 10.8374
346 1RP0 AHZ 0.003134 0.4207 10.9155
347 5I39 FAD 0.005032 0.41885 10.9635
348 5U8U FAD 0.01544 0.41604 10.9635
349 2YVJ NAI 0.005597 0.41142 11.0092
350 4YUW S4M 0.002695 0.46703 11.2957
351 4YUW 4JU 0.002754 0.46703 11.2957
352 3S5W FAD 0.002589 0.42289 11.2957
353 1H82 GZZ 0.01605 0.41341 11.2957
354 1H82 FAD 0.01358 0.41341 11.2957
355 1JQ3 AAT 0.0001391 0.41959 11.4865
356 1NVM NAD 0.001685 0.43337 11.5385
357 3A25 SAM 0.0000656 0.49628 11.6279
358 4Z24 FAD 0.01189 0.40648 11.6279
359 3WV8 ATP 0.001385 0.41474 11.9266
360 3NTD FAD 0.009181 0.40756 11.9601
361 2I7C AAT 0.0001784 0.41344 12.0141
362 2OBF SAH 0.00318 0.43157 12.1107
363 2OBF F83 0.00318 0.43157 12.1107
364 4KIB SAH 0.00001278 0.47634 12.2924
365 1F3L SAH 0.0001378 0.46828 12.2924
366 2FKA BEF 0.009915 0.4367 12.4031
367 1Z3C SA8 0.0002785 0.46202 12.4161
368 5JE0 SAH 0.0001793 0.47158 12.5506
369 5JE0 AZ8 0.0001793 0.47158 12.5506
370 3ZNN 4WL 0.02428 0.40258 12.6246
371 3ZNN FAD 0.02428 0.40258 12.6246
372 5BW4 SAM 0.00001411 0.47411 12.7341
373 2F5Z FAD 0.006535 0.4188 12.9568
374 1YY5 FAD 0.007 0.41839 12.9568
375 1RSG FAD 0.007972 0.4141 12.9568
376 3RNM FAD 0.009682 0.4113 12.9568
377 1ZMD NAI 0.002025 0.40796 12.9568
378 1G60 SAM 0.0000001819 0.56001 13.0769
379 3JWH SAH 0.00004456 0.43664 13.3641
380 5XVQ SAH 0.0005476 0.43975 13.3803
381 5TTJ FAD 0.01188 0.40368 13.9535
382 2PWY SAH 0.0000005438 0.56151 14.3411
383 1SQF SAM 0.0000003029 0.59886 14.6179
384 1L1E SAH 0.00005396 0.46999 14.6341
385 3BXO SAM 0.0001776 0.42574 14.6444
386 1DL5 SAH 0.000005507 0.52732 14.9502
387 2GVC FAD 0.007496 0.40589 14.9502
388 1VQW FAD 0.008063 0.40455 14.9502
389 1LSS NAD 0.0008625 0.42377 15
390 1G8K MGD 0.01339 0.42069 15.7895
391 4PLG NAI 0.003632 0.42389 15.9468
392 2V3B FAD 0.01201 0.4015 16.3636
393 4EMJ FAD 0.01116 0.40487 17.757
394 3OU2 SAH 0.00003959 0.47091 18.8073
395 4POO SAM 0.000000000392 0.69212 19.5
396 2HMT NAI 0.003368 0.40469 20.1389
397 1E6E FAD 0.007183 0.41006 20.3125
398 2XVM SAH 0.0002628 0.41515 20.603
399 5EB4 FAD 0.009835 0.40823 24.9169
400 4J56 FAD 0.007581 0.41687 27.193
401 4GQB 0XU 0.00001817 0.50189 40.9091
402 5FA5 MTA 0.0001788 0.43144 45
Pocket No.: 2; Query (leader) PDB : 1N2X; Ligand: SAM; Similar sites found: 31
This union binding pocket(no: 2) in the query (biounit: 1n2x.bio1) has 26 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 2NU5 NAG 0.02607 0.413 None
2 2GUC MAN 0.02609 0.41074 None
3 2HYR BGC GLC 0.03032 0.40514 None
4 4BWL MN9 0.03327 0.40322 1.3289
5 4AU8 Z3R 0.01735 0.40834 2.36486
6 3GEG NAD 0.001791 0.42211 2.42915
7 4EUE NAI 0.007704 0.40146 2.65781
8 1NJR XYL 0.001672 0.40421 2.8169
9 3CQL NAG 0.03866 0.40046 2.88066
10 4YDD MGD 0.03475 0.40073 2.99003
11 4YDD MD1 0.03475 0.40073 2.99003
12 2WSB NAD 0.01293 0.40047 3.14961
13 2Q1S NAI 0.01228 0.40416 3.32226
14 1MV8 NAD 0.005709 0.40019 3.32226
15 4DSG FAD 0.02686 0.40016 3.32226
16 4DSG UDP 0.02686 0.40016 3.32226
17 3VM7 GLC 0.02302 0.41524 3.98671
18 5MZI FYK 0.0236 0.40271 4.98339
19 5MZI FAD 0.02285 0.40271 4.98339
20 2Y6Q I7T 0.01613 0.40153 4.98339
21 2Y6Q FAD 0.007672 0.40153 4.98339
22 2PFY PCA 0.03414 0.40514 5.31561
23 2PFZ PCA 0.04152 0.40006 6.31229
24 3WWX DIA 0.03529 0.40286 6.97674
25 1TLG GAL 0.04169 0.40114 7.2
26 3QVP FAD 0.01084 0.40652 8.63787
27 4FC7 COA 0.01197 0.40376 9.02527
28 4FC7 NAP 0.01197 0.40376 9.02527
29 2O07 SPD 0.001556 0.40086 9.63455
30 3SQP FAD 0.0233 0.43419 10.6312
31 1SQL GUN 0.02309 0.41181 10.9589
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