Receptor
PDB id Resolution Class Description Source Keywords
1NPL 2 Å NON-ENZYME: BINDING MANNOSE-SPECIFIC AGGLUTININ (LECTIN) FROM DAFFODIL (NARCISSU PSEUDONARCISSUS) BULBS IN COMPLEX WITH MANNOSE-ALPHA1,3-MAN NARCISSUS PSEUDONARCISSUS LECTIN AGGLUTININ MANNOBIOSE MANNOSE-ALPHA1 3-MANNOSE DSUGAR BINDING PROTEIN
Ref.: INSIGHTS INTO CARBOHYDRATE RECOGNITION BY NARCISSUS PSEUDONARCISSUS LECTIN: THE CRYSTAL STRUCTURE AT 2 RESOLUTION IN COMPLEX WITH ALPHA1-3 MANNOBIOSE. J.MOL.BIOL. V. 290 185 1999
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
MAN A:130;
A:131;
Valid;
Valid;
none;
none;
Kd = 2 mM
180.156 C6 H12 O6 C([C@...
MAN MAN A:110;
A:112;
A:120;
Valid;
Valid;
Valid;
none;
none;
none;
Kd = 2 mM
342.297 n/a O(C1O...
PO4 A:150;
A:151;
A:152;
Invalid;
Invalid;
Invalid;
none;
none;
none;
submit data
94.971 O4 P [O-]P...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1NPL 2 Å NON-ENZYME: BINDING MANNOSE-SPECIFIC AGGLUTININ (LECTIN) FROM DAFFODIL (NARCISSU PSEUDONARCISSUS) BULBS IN COMPLEX WITH MANNOSE-ALPHA1,3-MAN NARCISSUS PSEUDONARCISSUS LECTIN AGGLUTININ MANNOBIOSE MANNOSE-ALPHA1 3-MANNOSE DSUGAR BINDING PROTEIN
Ref.: INSIGHTS INTO CARBOHYDRATE RECOGNITION BY NARCISSUS PSEUDONARCISSUS LECTIN: THE CRYSTAL STRUCTURE AT 2 RESOLUTION IN COMPLEX WITH ALPHA1-3 MANNOBIOSE. J.MOL.BIOL. V. 290 185 1999
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 473 families.
1 1NPL Kd = 2 mM MAN C6 H12 O6 C([C@@H]1[....
70% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 355 families.
1 1MSA - MMA C7 H14 O6 CO[C@@H]1[....
2 1JPC - MAN MAN n/a n/a
3 1NPL Kd = 2 mM MAN C6 H12 O6 C([C@@H]1[....
50% Homology Family (6)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 272 families.
1 3A0D - MMA C7 H14 O6 CO[C@@H]1[....
2 3A0E - M3M C12 H22 O11 C([C@@H]1[....
3 4OIT Ka = 32.5 M^-1 MAN C6 H12 O6 C([C@@H]1[....
4 1MSA - MMA C7 H14 O6 CO[C@@H]1[....
5 1JPC - MAN MAN n/a n/a
6 1NPL Kd = 2 mM MAN C6 H12 O6 C([C@@H]1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: MAN; Similar ligands found: 141
No: Ligand ECFP6 Tc MDL keys Tc
1 GAL 1 1
2 BMA 1 1
3 GXL 1 1
4 GLA 1 1
5 ALL 1 1
6 GLC 1 1
7 BGC 1 1
8 GIV 1 1
9 MAN 1 1
10 WOO 1 1
11 32O 0.653846 0.866667
12 RIB 0.653846 0.866667
13 FUB 0.653846 0.866667
14 Z6J 0.653846 0.866667
15 AHR 0.653846 0.866667
16 BMA BMA MAN 0.545455 0.823529
17 GLA BGC 0.511628 0.848485
18 LAK 0.511628 0.848485
19 BGC GLA 0.511628 0.848485
20 GLA BMA 0.511628 0.848485
21 MAN BMA 0.511628 0.848485
22 GLA GLC 0.511628 0.848485
23 GAL GAL 0.511628 0.848485
24 MLB 0.511628 0.848485
25 BMA GLA 0.511628 0.848485
26 BMA BMA BMA BMA BMA BMA MAN 0.5 0.823529
27 YDR 0.5 0.8
28 MAN BMA BMA BMA BMA BMA 0.5 0.823529
29 GLC GLC GLC GLC BGC 0.488889 0.848485
30 GLC GLC GLC 0.488889 0.848485
31 MAN MAN MAN 0.488889 0.848485
32 GLC GLC GLC GLC GLC BGC 0.488889 0.848485
33 BGP 0.461538 0.675
34 G6P 0.461538 0.675
35 M6P 0.461538 0.675
36 A6P 0.461538 0.675
37 M6D 0.461538 0.675
38 BG6 0.461538 0.675
39 SHG 0.457143 0.875
40 GAF 0.457143 0.875
41 G2F 0.457143 0.875
42 X6X 0.457143 0.777778
43 2FG 0.457143 0.875
44 G3F 0.457143 0.875
45 PA1 0.457143 0.777778
46 1GN 0.457143 0.777778
47 GCS 0.457143 0.777778
48 2H5 0.457143 0.875
49 LB2 0.454545 0.848485
50 BGC BMA 0.454545 0.848485
51 BGC GAL 0.454545 0.848485
52 MAL 0.454545 0.848485
53 GLC GAL 0.454545 0.848485
54 M3M 0.454545 0.848485
55 GLA GAL 0.454545 0.848485
56 MAB 0.454545 0.848485
57 GLC BGC 0.454545 0.848485
58 BMA BMA 0.454545 0.848485
59 LBT 0.454545 0.848485
60 MAL MAL 0.454545 0.823529
61 CBK 0.454545 0.848485
62 GLA GLA 0.454545 0.848485
63 MAN GLC 0.454545 0.848485
64 CBI 0.454545 0.848485
65 N9S 0.454545 0.848485
66 GAL GLC 0.454545 0.848485
67 BMA GAL 0.454545 0.848485
68 B2G 0.454545 0.848485
69 BGC GLC 0.454545 0.848485
70 LAT 0.454545 0.848485
71 GAL BGC 0.454545 0.848485
72 3MG 0.444444 0.875
73 TCB 0.444444 0.8
74 GLC SGC 0.444444 0.8
75 YIO 0.441176 0.870968
76 2GS 0.432432 0.875
77 BGC BGC 0.431818 0.848485
78 2M4 0.431818 0.848485
79 MAN MAN 0.431818 0.848485
80 AHR AHR 0.428571 0.764706
81 GLF 0.428571 0.84375
82 FUB AHR 0.428571 0.764706
83 CT3 0.416667 0.848485
84 GLC BGC GLC 0.416667 0.848485
85 MLR 0.416667 0.848485
86 GLC GLC GLC GLC GLC GLC GLC 0.416667 0.848485
87 GLC GLC GLC GLC GLC 0.416667 0.848485
88 GAL FUC 0.416667 0.848485
89 BMA BMA BMA 0.416667 0.848485
90 CTR 0.416667 0.848485
91 BGC GLC GLC 0.416667 0.848485
92 BGC GLC GLC GLC GLC 0.416667 0.848485
93 MAN MAN BMA BMA BMA BMA 0.416667 0.848485
94 GLC GAL GAL 0.416667 0.848485
95 B4G 0.416667 0.848485
96 CEX 0.416667 0.848485
97 MAN BMA BMA BMA BMA 0.416667 0.848485
98 BMA BMA BMA BMA BMA 0.416667 0.848485
99 GLC BGC BGC BGC BGC BGC 0.416667 0.848485
100 CTT 0.416667 0.848485
101 GLC GLC BGC 0.416667 0.848485
102 DXI 0.416667 0.848485
103 GLC GLC BGC GLC GLC GLC GLC 0.416667 0.848485
104 BGC GLC GLC GLC 0.416667 0.848485
105 BGC BGC BGC GLC 0.416667 0.848485
106 BGC BGC BGC BGC BGC BGC 0.416667 0.848485
107 BMA BMA BMA BMA BMA BMA 0.416667 0.848485
108 MTT 0.416667 0.848485
109 BMA MAN BMA 0.416667 0.848485
110 BGC GLC GLC GLC GLC GLC GLC 0.416667 0.848485
111 CE5 0.416667 0.848485
112 GAL GAL GAL 0.416667 0.848485
113 BGC BGC BGC BGC BGC BGC BGC BGC BGC 0.416667 0.848485
114 GLC GLC GLC GLC GLC GLC GLC GLC GLC 0.416667 0.848485
115 GLA GAL GLC 0.416667 0.848485
116 CE6 0.416667 0.848485
117 GLC BGC BGC BGC BGC 0.416667 0.848485
118 GLC BGC BGC 0.416667 0.848485
119 MAN BMA BMA 0.416667 0.848485
120 MT7 0.416667 0.848485
121 GLC GLC GLC GLC GLC GLC GLC GLC 0.416667 0.848485
122 CE8 0.416667 0.848485
123 CEY 0.416667 0.848485
124 BGC BGC BGC 0.408163 0.848485
125 BGC BGC BGC BGC BGC 0.408163 0.848485
126 GLC BGC BGC BGC BGC BGC BGC 0.408163 0.848485
127 SGC SGC BGC 0.408163 0.8
128 GLC BGC BGC BGC 0.408163 0.848485
129 BGC BGC BGC ASO BGC BGC ASO 0.408163 0.848485
130 BGC BGC BGC GLC BGC BGC 0.408163 0.848485
131 TRE 0.405405 0.848485
132 1LL 0.405405 0.771429
133 TDG 0.405405 0.771429
134 BM3 0.404762 0.7
135 NDG 0.404762 0.7
136 NAG 0.404762 0.7
137 HSQ 0.404762 0.7
138 A2G 0.404762 0.7
139 NGA 0.404762 0.7
140 FUB AHR AHR 0.4 0.764706
141 AHR AHR AHR 0.4 0.764706
Ligand no: 2; Ligand: MAN MAN; Similar ligands found: 243
No: Ligand ECFP6 Tc MDL keys Tc
1 MAN MAN 1 1
2 BGC BGC 1 1
3 2M4 1 1
4 BMA BMA MAN 0.886364 0.970588
5 MAN MAN BMA 0.808511 1
6 MAN MAN MAN GLC 0.690909 1
7 FUC GAL 0.66 0.941176
8 GAL NAG MAN 0.612903 0.733333
9 MAN NAG GAL 0.612903 0.733333
10 BGC GLC 0.612245 1
11 GLC BGC 0.612245 1
12 B2G 0.612245 1
13 GLA GAL 0.612245 1
14 LAT 0.612245 1
15 GLC GAL 0.612245 1
16 CBK 0.612245 1
17 BGC GAL 0.612245 1
18 MAL MAL 0.612245 0.970588
19 GLA GLA 0.612245 1
20 GAL GLC 0.612245 1
21 BMA GAL 0.612245 1
22 MAB 0.612245 1
23 GAL BGC 0.612245 1
24 CBI 0.612245 1
25 BMA BMA 0.612245 1
26 BGC BMA 0.612245 1
27 LB2 0.612245 1
28 MAN GLC 0.612245 1
29 LBT 0.612245 1
30 N9S 0.612245 1
31 M3M 0.612245 1
32 MAL 0.612245 1
33 TRE 0.595238 1
34 GLA MBG 0.591837 0.942857
35 BGC BGC BGC ASO BGC BGC ASO 0.584906 1
36 GLC BGC BGC BGC BGC BGC BGC 0.584906 1
37 BGC BGC BGC 0.584906 1
38 BGC BGC BGC GLC BGC BGC 0.584906 1
39 BGC BGC BGC BGC BGC 0.584906 1
40 GLC BGC BGC BGC 0.584906 1
41 M6P MAN MAN 0.580645 0.785714
42 BMA MAN MAN 0.571429 1
43 GLA GAL GLC 0.566038 1
44 BGC GLC GLC GLC 0.566038 1
45 GAL GAL GAL 0.566038 1
46 BGC BGC BGC BGC BGC BGC BGC BGC BGC 0.566038 1
47 BGC BGC BGC BGC BGC BGC 0.566038 1
48 BMA MAN BMA 0.566038 1
49 GLC BGC BGC BGC BGC 0.566038 1
50 CE6 0.566038 1
51 BGC GLC GLC GLC GLC GLC GLC 0.566038 1
52 MTT 0.566038 1
53 GLC BGC BGC 0.566038 1
54 CEY 0.566038 1
55 MT7 0.566038 1
56 CE5 0.566038 1
57 BMA BMA BMA BMA BMA BMA 0.566038 1
58 GLC GLC GLC GLC GLC GLC GLC GLC GLC 0.566038 1
59 BGC BGC BGC GLC 0.566038 1
60 GLC GLC GLC GLC GLC GLC GLC GLC 0.566038 1
61 MLR 0.566038 1
62 BMA BMA BMA 0.566038 1
63 CEX 0.566038 1
64 BGC GLC GLC 0.566038 1
65 CTR 0.566038 1
66 BGC GLC GLC GLC GLC 0.566038 1
67 GLC BGC GLC 0.566038 1
68 CT3 0.566038 1
69 GLC GLC BGC GLC GLC GLC GLC 0.566038 1
70 MAN MAN BMA BMA BMA BMA 0.566038 1
71 CTT 0.566038 1
72 DXI 0.566038 1
73 MAN BMA BMA BMA BMA 0.566038 1
74 GLC GAL GAL 0.566038 1
75 BMA BMA BMA BMA BMA 0.566038 1
76 B4G 0.566038 1
77 MAN BMA BMA 0.566038 1
78 GLC BGC BGC BGC BGC BGC 0.566038 1
79 CE8 0.566038 1
80 GLC GLC GLC GLC GLC GLC GLC 0.566038 1
81 GLC GLC GLC GLC GLC 0.566038 1
82 GLC GLC BGC 0.566038 1
83 LAT GLA 0.56 1
84 MAN BMA BMA BMA BMA BMA 0.553571 0.970588
85 BMA BMA BMA BMA BMA BMA MAN 0.553571 0.970588
86 BGC BGC GLC 0.553571 1
87 MAN NAG 0.551724 0.733333
88 GLA GAL GAL 0.54386 1
89 GLA GAL BGC 0.54386 1
90 GAL GAL FUC 0.542373 0.970588
91 GLA GAL FUC 0.542373 0.970588
92 GLA GLA FUC 0.542373 0.970588
93 FUC GLA GLA 0.542373 0.970588
94 FUC GAL GLA 0.542373 0.970588
95 U63 0.537037 0.891892
96 GAL FUC 0.537037 0.941176
97 RZM 0.528302 0.688889
98 M13 0.528302 0.942857
99 MDM 0.528302 0.942857
100 GAL MBG 0.528302 0.942857
101 DR5 0.528302 0.942857
102 MMA MAN 0.528302 0.942857
103 GLA EGA 0.527273 0.942857
104 DOM 0.518519 0.942857
105 BMA MAN 0.518519 0.914286
106 FMO 0.508772 0.868421
107 A2G GAL 0.508475 0.733333
108 GAL A2G 0.508475 0.733333
109 GAL NGA 0.508475 0.733333
110 BGC BGC BGC BGC BGC BGC BGC BGC 0.508197 1
111 BGC BGC BGC BGC 0.508197 1
112 MAL EDO 0.491228 0.942857
113 GLA MAN ABE 0.484848 0.916667
114 NDG GAL 0.483333 0.733333
115 GAL NDG 0.483333 0.733333
116 NLC 0.483333 0.733333
117 NOJ GLC 0.482759 0.727273
118 AMG 0.478261 0.857143
119 MMA 0.478261 0.857143
120 GYP 0.478261 0.857143
121 MBG 0.478261 0.857143
122 GAL NGA A2G 0.476923 0.673469
123 ABL 0.474576 0.702128
124 MVP 0.474576 0.733333
125 CGC 0.474576 0.941176
126 5QP 0.473684 0.885714
127 FRU GAL 0.473684 0.842105
128 NOY BGC 0.473684 0.75
129 BMA FRU 0.473684 0.842105
130 T6P 0.472727 0.767442
131 GLC GLC GLC GLC GLC GLC 0.46875 1
132 GAL GAL SO4 0.467742 0.702128
133 BMA IFM 0.465517 0.744186
134 MAN MNM 0.465517 0.75
135 IFM BMA 0.465517 0.744186
136 9MR 0.465517 0.744186
137 BGC OXZ 0.465517 0.666667
138 IFM BGC 0.465517 0.744186
139 FUC BGC GAL 0.460317 0.970588
140 G2F BGC BGC BGC BGC BGC 0.460317 0.868421
141 GLA GAL BGC 5VQ 0.459016 0.891892
142 GLC DMJ 0.457627 0.727273
143 MAN DGO 0.448276 0.914286
144 BMA BMA GLA BMA BMA 0.447761 1
145 2GS 0.446809 0.857143
146 GLC GLC XYP 0.446154 1
147 P3M 0.446154 0.767442
148 GAL BGC BGC XYS 0.442857 0.942857
149 GLA GAL NAG 0.441176 0.733333
150 NAG GAL GAL 0.441176 0.733333
151 MAN BMA NAG 0.441176 0.733333
152 MAN MAN MAN MAN 0.439394 1
153 SOR GLC GLC 0.439394 0.970588
154 MAN MAN BMA MAN 0.439394 1
155 MAN 7D1 0.438596 0.888889
156 NAG BMA 0.4375 0.653061
157 GLC GLC GLC GLC 0.4375 1
158 GLA GAL GLC NBU 0.4375 0.846154
159 MAN MAN MAN BMA MAN 0.43662 1
160 8VZ 0.435484 0.673469
161 GAL MGC 0.435484 0.702128
162 GLC GLC GLC BGC 0.432836 1
163 MAN BMA MAN MAN MAN 0.432836 1
164 M5S 0.432836 1
165 MAN 0.431818 0.848485
166 GAL 0.431818 0.848485
167 BMA 0.431818 0.848485
168 ALL 0.431818 0.848485
169 WOO 0.431818 0.848485
170 GXL 0.431818 0.848485
171 GLC 0.431818 0.848485
172 GLA 0.431818 0.848485
173 BGC 0.431818 0.848485
174 GIV 0.431818 0.848485
175 BGC BGC G2F SHG 0.430556 0.846154
176 MLB 0.428571 1
177 BGC GLA 0.428571 1
178 KHO 0.428571 0.888889
179 GLA BGC 0.428571 1
180 MAN BMA 0.428571 1
181 GAL GAL 0.428571 1
182 LAK 0.428571 1
183 GLA GLC 0.428571 1
184 GLA BMA 0.428571 1
185 BMA GLA 0.428571 1
186 SOR GLC GLC GLC 0.426471 0.970588
187 LAG 0.426471 0.6
188 GAL BGC NAG GAL 0.424658 0.733333
189 OXZ BGC BGC 0.424242 0.6875
190 LAT FUC 0.424242 0.970588
191 BGC GAL FUC 0.424242 0.970588
192 FUC GAL GLC 0.424242 0.970588
193 UMQ 0.424242 0.785714
194 GLC GAL FUC 0.424242 0.970588
195 G3I 0.424242 0.767442
196 DMU 0.424242 0.785714
197 LMU 0.424242 0.785714
198 FUC LAT 0.424242 0.970588
199 LMT 0.424242 0.785714
200 G2I 0.424242 0.767442
201 BTU 0.423729 0.842105
202 TUR 0.423729 0.842105
203 LAT NAG GAL 0.418919 0.733333
204 BGC GAL NAG GAL 0.418919 0.733333
205 GAL NAG GAL BGC 0.418919 0.733333
206 BGC GLA GAL FUC 0.416667 0.970588
207 ISX 0.416667 0.761905
208 MAN MMA MAN 0.415385 0.942857
209 NPJ 0.414286 0.622642
210 GLC GLC GLC 0.413793 1
211 MAN MAN MAN 0.413793 1
212 GLC GLC GLC GLC GLC BGC 0.413793 1
213 GLC GLC GLC GLC BGC 0.413793 1
214 NAG GAL GAL NAG GAL 0.413333 0.6875
215 GLC GLC XYS 0.411765 0.970588
216 G1P 0.411765 0.697674
217 ALX 0.411765 0.697674
218 GL1 0.411765 0.697674
219 BNX 0.411765 0.697674
220 M1P 0.411765 0.697674
221 XGP 0.411765 0.697674
222 56N 0.410714 0.833333
223 MAN IFM 0.409836 0.761905
224 GLC IFM 0.409836 0.761905
225 FUC NDG GAL 0.408451 0.717391
226 OPM MAN MAN 0.408451 0.804878
227 GAL NDG FUC 0.408451 0.717391
228 FUC NAG GAL 0.408451 0.717391
229 GAL NAG FUC 0.408451 0.717391
230 GLC GAL NAG GAL 0.407895 0.733333
231 LSE 0.405797 0.6875
232 6UZ 0.405797 0.846154
233 GLC 7LQ 0.403226 0.885714
234 GAL NGT 0.402985 0.66
235 BMA MVL 0.402985 0.6
236 MVL BMA 0.402985 0.6
237 IDC 0.402985 0.6
238 NGT GAL 0.402985 0.66
239 RCB 0.402778 0.622642
240 GLO GLC GLC 0.402778 0.942857
241 GTM BGC BGC 0.4 0.868421
242 GLC GLC BGC XYS BGC XYS 0.4 0.942857
243 10M 0.4 0.733333
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1NPL; Ligand: MAN; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 1npl.bio1) has 4 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 2; Query (leader) PDB : 1NPL; Ligand: MAN; Similar sites found: 86
This union binding pocket(no: 2) in the query (biounit: 1npl.bio1) has 7 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 4TMK T5A 0.0001018 0.50497 None
2 1SS4 GSH 0.001864 0.50399 None
3 1GXU 2HP 0.000002617 0.48353 None
4 4PNO U5P 0.000422 0.4407 None
5 3KPE TM3 0.003605 0.43689 None
6 1NU4 MLA 0.04484 0.4167 None
7 2FWP ICR 0.001259 0.41654 None
8 2FWP CIT 0.001375 0.41003 None
9 3UEC ALA ARG TPO LYS 0.01995 0.4086 None
10 2BGM NAJ 0.01137 0.40113 None
11 1SAZ ACP 0.000001963 0.55401 1.83486
12 3IHB TRS 0.0003061 0.53643 3.66972
13 3DNT ATP 0.00434 0.48412 3.66972
14 2HVK TBA 0.000004495 0.56788 4.58716
15 2YD6 FLC 0.000547 0.55277 4.58716
16 3NOJ PYR 0.00007146 0.50085 4.58716
17 1W55 GPP 0.0000001509 0.48106 4.58716
18 1W55 C 0.0002516 0.45426 4.58716
19 3PHQ KDO 0.01459 0.45083 4.58716
20 5T63 ALA ALA ALA ALA 0.0001111 0.43196 4.58716
21 4M5P 23W 0.013 0.42361 4.58716
22 1R0X ATP 0.001873 0.40819 4.58716
23 1MRE GDP 0.0275 0.40475 4.58716
24 4BPM GSH 0.0002214 0.40407 4.58716
25 3GD8 BOG 0.000058 0.53802 5.50459
26 1E4I NFG 0.00000000915 0.52478 5.50459
27 3IB9 BTN 0.0008806 0.47628 5.50459
28 1BZL FAD 0.01663 0.46976 5.50459
29 1A5Z FBP 0.00003849 0.45649 5.50459
30 1OFH ADP 0.000567 0.44964 5.50459
31 1NME 159 0.0004214 0.44073 5.50459
32 1NXJ GLV 0.00147 0.43578 5.50459
33 1A5Z OXM 0.0098 0.42961 5.50459
34 1NXJ TLA 0.0006082 0.42749 5.50459
35 2GN2 C5P 0.0005805 0.4259 5.50459
36 1RZM E4P 0.01276 0.41776 5.50459
37 4TSK NDP 0.004925 0.41446 5.50459
38 3B9Z CO2 0.007883 0.42153 6.42202
39 2BLE 5GP 0.0062 0.41222 6.42202
40 1O9U ADZ 0.04469 0.40298 6.42202
41 3SUC ATP 0.00000165 0.51949 7.33945
42 1LTH FBP 0.0001683 0.49693 7.33945
43 3ICV NAG 0.03735 0.4402 7.33945
44 2PAR TMP 0.0007674 0.43249 7.33945
45 1LTH OXM 0.002191 0.42352 7.33945
46 1Q3Q ANP 0.004016 0.41771 7.33945
47 1DL7 NCH 0.004469 0.40177 7.33945
48 2V9M CIT 0.008301 0.4006 7.33945
49 2NZ2 ASP 0.0001395 0.48464 8.25688
50 3FPZ AHZ 0.0008113 0.45581 8.25688
51 3IJH KO2 0.001801 0.44714 8.25688
52 3VOZ 04A 0.0002527 0.43861 8.25688
53 3K3G MMU 0.007275 0.41482 8.25688
54 3FN0 TRP ASN TRP PHE ASP ILE THR ASN LYS 0.006386 0.42567 8.65801
55 1Y0L HAN 0.0001657 0.53864 8.84956
56 4ODV GP1 Z9M 0.0002218 0.54525 9.17431
57 1IZC PYR 0.0000004435 0.50795 9.17431
58 2BZ1 TAU 0.002889 0.48334 9.17431
59 1JA9 NDP 0.004686 0.42201 9.17431
60 5DTF 5CT 0.001101 0.48029 10.0917
61 1V5F FAD 0.003458 0.45337 10.0917
62 1V5F TPP 0.003458 0.45337 10.0917
63 5DS8 GLY 5CT GLY ALA 0.003509 0.45136 10.0917
64 5DUB GLY 5GG GLY ALA 0.007853 0.43788 10.0917
65 4OYA 1VE 0.01398 0.41603 10.0917
66 1ZFJ IMP 0.00001463 0.532 11.0092
67 4M7F BM3 0.0001695 0.48108 11.0092
68 3O03 GCO 0.001315 0.42231 11.0092
69 4LO6 SIA GAL 0.0002472 0.50259 11.9266
70 2BMK PDD 0.002286 0.44924 11.9266
71 4EGC MAL 0.006233 0.44839 11.9266
72 5T85 44G 0.01142 0.42312 11.9266
73 4HPP GLU 0.00001068 0.40026 11.9266
74 4NTX AMR 0.005932 0.41863 13.7615
75 4MOB ADP 0.002107 0.40822 13.7615
76 4F8L GAL 0.0004404 0.44542 14.4828
77 3OAZ 2M5 0.0001713 0.54446 14.6789
78 4G1V FAD 0.0002002 0.48694 14.6789
79 3R51 MMA 0.02303 0.41781 14.6789
80 3VPD BUA 0.005884 0.47374 15.5963
81 3VPD CIT 0.03911 0.41258 15.5963
82 5DSC GLY 5CT GLY SER GLY 0.0212 0.40463 16.5138
83 1CLY FUC GAL NAG NON FUC 0.01978 0.40087 17.4312
84 5D6C 57S 0.002933 0.46782 18.3486
85 5DRN 5CT 0.001139 0.48911 20.1835
86 4JLV ADP 0.01641 0.40607 26.6055
Pocket No.: 3; Query (leader) PDB : 1NPL; Ligand: MAN; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 3) in the query (biounit: 1npl.bio2) has 4 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 4; Query (leader) PDB : 1NPL; Ligand: MAN MAN; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 1npl.bio2) has 7 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 5; Query (leader) PDB : 1NPL; Ligand: MAN MAN; Similar sites found: 25
This union binding pocket(no: 5) in the query (biounit: 1npl.bio2) has 10 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1NU4 MLA 0.001407 0.45084 None
2 4LWA Q13 0.02568 0.42791 1.83486
3 4PO2 ASN ARG LEU LEU LEU THR GLY 0.02682 0.41111 4.58716
4 4M5P MLA 0.00995 0.41006 4.58716
5 1TDF FAD 0.006967 0.4638 5.50459
6 1GAD NAD 0.005732 0.44724 5.50459
7 3VHZ L2P GLC MAN SGA 0.04243 0.43346 5.50459
8 2H6B 3C4 0.01816 0.42094 5.50459
9 2D37 FMN 0.03941 0.40542 5.50459
10 2D37 NAD 0.04172 0.40542 5.50459
11 3UH0 TSB 0.03317 0.40509 5.50459
12 1HEX NAD 0.0171 0.42494 6.42202
13 3A8U PLP 0.03329 0.40644 7.33945
14 2NW9 FT6 0.0129 0.40014 7.33945
15 4HP0 NOJ NAG NAG NAG 0.01774 0.4204 9.17431
16 4R33 TRP 0.02992 0.41957 9.17431
17 4R33 SAH 0.02992 0.41957 9.17431
18 4DXJ 0M9 0.01016 0.41296 9.17431
19 2BZ1 TAU 0.01761 0.4065 9.17431
20 3WJP ANP 0.01138 0.42125 10.0917
21 1X54 4AD 0.02525 0.41242 10.0917
22 2J8Z NAP 0.0431 0.4059 10.0917
23 1R27 MGD 0.01521 0.43678 11.9266
24 3C1O NAP 0.0269 0.41105 12.844
25 4LED XXR 0.000037 0.54668 37.6147
Pocket No.: 6; Query (leader) PDB : 1NPL; Ligand: MAN; Similar sites found: 54
This union binding pocket(no: 6) in the query (biounit: 1npl.bio2) has 7 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 2BGM MAX 0.0000258 0.53799 None
2 3ZY6 GFB 0.001804 0.44862 None
3 1JGS SAL 0.003824 0.44772 None
4 2P4T NAP 0.003927 0.44716 None
5 4OK9 HIS 0.00224 0.44049 None
6 2V5K OXM 0.0001377 0.41025 None
7 1T57 FMN 0.01629 0.40723 None
8 2XI7 XI7 0.02744 0.40335 None
9 4Q3F TLA 0.0007048 0.40304 None
10 1UO5 PIH 0.02821 0.40273 None
11 3EJ0 11X 0.001611 0.4023 None
12 1OMZ UD2 0.00000587 0.59769 2.75229
13 43CA NPO 0.01106 0.42794 2.75229
14 4RJK PYR 0.0008275 0.482 3.66972
15 3H86 AP5 0.01544 0.43812 3.66972
16 1H9G COA MYR 0.02113 0.40784 4.58716
17 4PO2 ASN ARG LEU LEU LEU THR GLY 0.02221 0.4011 4.58716
18 2H6B 3C4 0.0002406 0.52929 5.50459
19 4TSK TLA 0.0001378 0.4965 5.50459
20 3VHZ L2P GLC MAN SGA 0.002758 0.48409 5.50459
21 3VHZ SOG 0.002397 0.48409 5.50459
22 3F81 STT 0.01214 0.40519 5.50459
23 4B16 NAG 0.01787 0.40468 5.50459
24 1RRC ADP 0.00004109 0.52454 6.42202
25 4HZX G39 0.005 0.45139 6.42202
26 3VCA PRO 0.0004685 0.42417 6.42202
27 4DN8 BMA 0.002707 0.41307 6.42202
28 2ZWS PLM 0.01829 0.41254 6.42202
29 3A8U PLP 0.00005611 0.52262 7.33945
30 2DUA OXL 0.0002018 0.48912 7.33945
31 2QIA U20 0.002268 0.47957 7.33945
32 4LWM MHO 0.02564 0.41818 7.33945
33 1RYD GLC 0.004113 0.40559 7.33945
34 1RY2 AMP 0.00026 0.49411 8.25688
35 2X0K PPV 0.003777 0.41202 8.25688
36 1JA9 PYQ 0.00000175 0.59992 9.17431
37 3L6R MLI 0.003994 0.41267 9.17431
38 4R33 SAH 0.02656 0.41036 9.17431
39 4R33 TRP 0.02656 0.41036 9.17431
40 4HGP KDO 0.001186 0.47674 10.0917
41 3VKX T3 0.00499 0.42787 10.0917
42 1X54 4AD 0.01643 0.4101 10.0917
43 1P9P SAH 0.00723 0.42323 10.3448
44 1YOA FMN 0.005982 0.43768 11.0092
45 1FIQ SAL 0.02561 0.41001 11.0092
46 3CL7 HYN 0.0000509 0.52455 11.9266
47 1MG1 MAL 0.0005804 0.47269 11.9266
48 3Q9T FAY 0.04677 0.40341 11.9266
49 4N02 FNR 0.00002 0.58098 12.844
50 3CBG 4FE 0.0009335 0.46761 14.6789
51 1SBZ FMN 0.00269 0.45617 22.0183
52 3PAK MAN 0.001347 0.447 22.9358
53 2AEB ABH 0.0005992 0.48885 25.6881
54 2XBP ATP 0.01544 0.4335 27.5229
Pocket No.: 7; Query (leader) PDB : 1NPL; Ligand: MAN MAN; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 7) in the query (biounit: 1npl.bio2) has 6 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
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