Receptor
PDB id Resolution Class Description Source Keywords
1NV8 2.2 Å EC: 2.1.1.- N5-GLUTAMINE METHYLTRANSFERASE, HEMK THERMOTOGA MARITIMA CLASS I ADOMET-DEPENDENT METHYLTRANSFERASE
Ref.: STRUCTURES ALONG THE CATALYTIC PATHWAY OF PRMC/HEMK, AN N(5)-GLUTAMINE ADOMET-DEPENDENT METHYLTRANSFERASE BIOCHEMISTRY V. 42 5592 2003
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
MEQ A:400;
B:401;
Valid;
Valid;
none;
none;
submit data
160.171 C6 H12 N2 O3 CNC(=...
SAM A:300;
B:301;
Valid;
Valid;
none;
none;
submit data
398.437 C15 H22 N6 O5 S C[S@@...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1NV8 2.2 Å EC: 2.1.1.- N5-GLUTAMINE METHYLTRANSFERASE, HEMK THERMOTOGA MARITIMA CLASS I ADOMET-DEPENDENT METHYLTRANSFERASE
Ref.: STRUCTURES ALONG THE CATALYTIC PATHWAY OF PRMC/HEMK, AN N(5)-GLUTAMINE ADOMET-DEPENDENT METHYLTRANSFERASE BIOCHEMISTRY V. 42 5592 2003
Members (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 57 families.
1 1NV8 - SAM C15 H22 N6 O5 S C[S@@+](CC....
2 1SG9 - SAM C15 H22 N6 O5 S C[S@@+](CC....
3 1NV9 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
70% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 50 families.
1 1NV8 - SAM C15 H22 N6 O5 S C[S@@+](CC....
2 1SG9 - SAM C15 H22 N6 O5 S C[S@@+](CC....
3 1NV9 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
50% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 44 families.
1 1NV8 - SAM C15 H22 N6 O5 S C[S@@+](CC....
2 1SG9 - SAM C15 H22 N6 O5 S C[S@@+](CC....
3 1NV9 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: MEQ; Similar ligands found: 17
No: Ligand ECFP6 Tc MDL keys Tc
1 MEQ 1 1
2 HGA 0.617647 0.675
3 ONL 0.529412 0.757576
4 GLN 0.515152 0.870968
5 DGL 0.515152 0.71875
6 GLU 0.515152 0.71875
7 DGN 0.515152 0.870968
8 GGL 0.515152 0.71875
9 3GC 0.5 0.710526
10 NVA 0.454545 0.636364
11 HSE 0.424242 0.611111
12 HGS 0.423077 0.613636
13 MLZ 0.414634 0.641026
14 GSH 0.411765 0.658537
15 API 0.411765 0.69697
16 NLE 0.405405 0.647059
17 GSM 0.4 0.690476
Ligand no: 2; Ligand: SAM; Similar ligands found: 192
No: Ligand ECFP6 Tc MDL keys Tc
1 SAM 1 1
2 SMM 0.792683 0.96
3 S4M 0.6875 0.909091
4 S7M 0.670455 0.945946
5 M2T 0.636364 0.878378
6 GEK 0.612903 0.931507
7 SAI 0.571429 0.878378
8 XYA 0.565789 0.773333
9 ADN 0.565789 0.773333
10 RAB 0.565789 0.773333
11 5CD 0.564103 0.783784
12 EP4 0.5625 0.826667
13 SA8 0.56044 0.945205
14 SFG 0.555556 0.875
15 5X8 0.555556 0.888889
16 5N5 0.551282 0.773333
17 A4D 0.544304 0.797297
18 EEM 0.542553 0.945946
19 SAH 0.537634 0.916667
20 DTA 0.536585 0.789474
21 62X 0.535354 0.884615
22 MTA 0.53012 0.875
23 3DH 0.517647 0.849315
24 AMP MG 0.511364 0.710843
25 5AL 0.510417 0.743902
26 VMS 0.510204 0.673913
27 54H 0.510204 0.673913
28 0UM 0.51 0.857143
29 A 0.505747 0.707317
30 AMP 0.505747 0.707317
31 ABM 0.505618 0.753086
32 A5A 0.505155 0.688889
33 DAL AMP 0.50505 0.765432
34 NVA LMS 0.504951 0.725275
35 K15 0.5 0.883117
36 6RE 0.5 0.78481
37 5AD 0.5 0.75
38 SSA 0.5 0.684783
39 SON 0.5 0.746988
40 SRP 0.5 0.746988
41 LSS 0.49505 0.706522
42 CA0 0.494624 0.714286
43 A12 0.494505 0.705882
44 AP2 0.494505 0.705882
45 ME8 0.490385 0.841463
46 5CA 0.49 0.684783
47 TSB 0.49 0.681319
48 53H 0.49 0.666667
49 ACP 0.489362 0.694118
50 5AS 0.48913 0.648936
51 ADP 0.48913 0.690476
52 A2D 0.488889 0.690476
53 J7C 0.488889 0.772152
54 ZAS 0.488636 0.769231
55 8QN 0.485149 0.743902
56 GAP 0.484536 0.73494
57 AN2 0.483871 0.682353
58 A3S 0.483871 0.813333
59 A7D 0.483871 0.851351
60 GJV 0.483516 0.775
61 SRA 0.483146 0.694118
62 LAD 0.480769 0.752941
63 KAA 0.480769 0.698925
64 GSU 0.480769 0.722222
65 AMO 0.480392 0.746988
66 DSZ 0.480392 0.703297
67 52H 0.48 0.666667
68 ADP MG 0.478723 0.702381
69 M33 0.478723 0.722892
70 MAO 0.478261 0.82716
71 BA3 0.478261 0.690476
72 AOC 0.477778 0.776316
73 DSH 0.477778 0.842105
74 NEC 0.477778 0.75
75 SXZ 0.47619 0.894737
76 AHX 0.475728 0.701149
77 Y3J 0.47561 0.706667
78 G5A 0.474227 0.684783
79 A3T 0.473684 0.8
80 ADP BEF 0.473684 0.686047
81 BEF ADP 0.473684 0.686047
82 B4P 0.473118 0.690476
83 AP5 0.473118 0.690476
84 A3N 0.472527 0.766234
85 KB1 0.471698 0.833333
86 LEU LMS 0.471154 0.706522
87 APC 0.46875 0.705882
88 PRX 0.46875 0.73494
89 PAJ 0.466019 0.712644
90 4AD 0.466019 0.759036
91 RBY 0.463918 0.72619
92 ADP PO3 0.463918 0.728395
93 ADV 0.463918 0.72619
94 ADX 0.463158 0.666667
95 MHZ 0.463158 0.82716
96 AU1 0.463158 0.674419
97 YAP 0.462963 0.738095
98 TXA 0.462264 0.72619
99 NB8 0.462264 0.72093
100 A3G 0.461538 0.802632
101 VRT 0.459184 0.842105
102 ATP MG 0.459184 0.702381
103 YSA 0.458716 0.684783
104 XAH 0.458716 0.715909
105 50T 0.458333 0.682353
106 ATP 0.458333 0.690476
107 7D7 0.45679 0.723684
108 ANP MG 0.455446 0.678161
109 KH3 0.455357 0.871795
110 ACQ 0.454545 0.694118
111 AQP 0.453608 0.690476
112 5FA 0.453608 0.690476
113 AR6 0.453608 0.710843
114 APR 0.453608 0.710843
115 NSS 0.451923 0.703297
116 FA5 0.449541 0.746988
117 AGS 0.44898 0.678161
118 SAP 0.44898 0.678161
119 A5D 0.44898 0.789474
120 AD9 0.44898 0.674419
121 PTJ 0.448598 0.72093
122 YLB 0.448276 0.758621
123 YLP 0.447368 0.738636
124 D3Y 0.446602 0.792208
125 ADP ALF 0.445545 0.678161
126 ALF ADP 0.445545 0.678161
127 TYR AMP 0.445455 0.746988
128 MYR AMP 0.444444 0.776471
129 3AM 0.444444 0.674699
130 OAD 0.443396 0.73494
131 2VA 0.443299 0.779221
132 OOB 0.442308 0.722892
133 S8M 0.442308 0.831169
134 ADP VO4 0.441176 0.702381
135 VO4 ADP 0.441176 0.702381
136 ANP 0.44 0.674419
137 TAT 0.44 0.686047
138 WAQ 0.439252 0.75
139 ARG AMP 0.438596 0.727273
140 YLC 0.435897 0.755814
141 AAT 0.435644 0.797468
142 3OD 0.435185 0.73494
143 1ZZ 0.435185 0.755814
144 NVA 2AD 0.434343 0.815789
145 DLL 0.433962 0.722892
146 00A 0.433962 0.689655
147 7MD 0.433628 0.715909
148 ATF 0.431373 0.666667
149 SO8 0.43 0.792208
150 3UK 0.429907 0.714286
151 A6D 0.429907 0.72619
152 5SV 0.428571 0.741176
153 AMP DBH 0.428571 0.714286
154 WSA 0.42735 0.692308
155 TYM 0.42735 0.746988
156 9SN 0.427273 0.681818
157 AHZ 0.426087 0.755814
158 A A 0.425926 0.710843
159 3NZ 0.425926 0.807692
160 P5A 0.425926 0.691489
161 PR8 0.425926 0.744186
162 A1R 0.424528 0.709302
163 2A5 0.424242 0.674419
164 7MC 0.423729 0.719101
165 7D5 0.422222 0.658824
166 FYA 0.422018 0.722892
167 JB6 0.422018 0.709302
168 AYB 0.421488 0.75
169 PLP AAD 0.419355 0.764045
170 A22 0.419048 0.682353
171 MAP 0.419048 0.659091
172 2AM 0.417582 0.666667
173 TAD 0.417391 0.712644
174 A3P 0.416667 0.686747
175 ADP BMA 0.416667 0.714286
176 25A 0.415094 0.690476
177 YLA 0.413223 0.719101
178 ADQ 0.411215 0.694118
179 48N 0.410256 0.72093
180 0XU 0.41 0.824324
181 NAD IBO 0.406504 0.717647
182 7D3 0.40625 0.643678
183 PAP 0.405941 0.678571
184 OVE 0.404255 0.662791
185 4UV 0.403509 0.697674
186 ALF ADP 3PG 0.403361 0.712644
187 AF3 ADP 3PG 0.403361 0.712644
188 LA8 ALF 3PG 0.403361 0.712644
189 3AD 0.402299 0.783784
190 CMP 0.402062 0.691358
191 2BA 0.402062 0.682927
192 7C5 0.4 0.731707
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1NV8; Ligand: MEQ; Similar sites found: 364
This union binding pocket(no: 1) in the query (biounit: 1nv8.bio1) has 30 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1P1C SAH 0.0002009 0.46468 None
2 2WG9 OCA 0.03266 0.40625 None
3 1UAY ADN 0.001481 0.45625 1.23967
4 2PXX SAH 0.00003331 0.51177 1.39535
5 4RDH AMP 0.0008611 0.46273 1.40845
6 4JK3 NAD 0.0005329 0.43668 1.5444
7 4J4H NAI 0.01678 0.43301 1.5444
8 4J4H 1J1 0.00232 0.42951 1.5444
9 3VSE SAH 0.000004689 0.44211 1.76056
10 1TDF NAP 0.02354 0.40142 1.76056
11 1TDF FAD 0.01105 0.40142 1.76056
12 1P77 ATR 0.02181 0.4156 1.83824
13 2F5Z FAD 0.001088 0.44014 2.11268
14 5U8U FAD 0.002613 0.43984 2.11268
15 5MBX SP5 0.002543 0.43377 2.11268
16 5MBX FAD 0.002543 0.43377 2.11268
17 3C6K MTA 0.001498 0.42684 2.11268
18 1ZMD NAI 0.001735 0.41957 2.11268
19 2B9W FAD 0.008409 0.41258 2.11268
20 3LCV SAM 0.0004173 0.42287 2.13523
21 4K28 NAD 0.001805 0.41887 2.23048
22 2EJU SAH 0.000000117 0.62703 2.46479
23 5JJR SAH 0.0001811 0.48422 2.46479
24 1OMO NAD 0.0005604 0.44263 2.46479
25 2YYY NAP 0.001028 0.41774 2.46479
26 4OPC FDA 0.01734 0.41742 2.46479
27 2VHW NAI 0.002963 0.415 2.46479
28 3ZG6 APR 0.005427 0.41144 2.46479
29 1RYI FAD 0.008206 0.40232 2.46479
30 1K0E TRP 0.02569 0.40024 2.46479
31 5CUQ NSC 0.0002231 0.45431 2.62172
32 3P2E SAH 0.0000244 0.51244 2.66667
33 3GJ8 GDP 0.01856 0.40721 2.71493
34 3GJ4 GDP 0.0221 0.40347 2.71493
35 1SQF SAM 0.000005574 0.55191 2.8169
36 1L1E SAH 0.000007465 0.53457 2.8169
37 1V59 NAD 0.0002595 0.49801 2.8169
38 3VYW SAM 0.0001295 0.48126 2.8169
39 2XT3 ADP 0.008169 0.44125 2.8169
40 1Q9I TEO 0.002117 0.4387 2.8169
41 3B6R CRN 0.01725 0.42284 2.8169
42 1DJN ADP 0.002531 0.41911 2.8169
43 3LXD FAD 0.002726 0.41529 2.8169
44 2R4J 13P 0.01108 0.40531 2.8169
45 1HE1 AF3 0.02328 0.41409 2.84091
46 2DT5 NAD 0.0005927 0.42682 2.8436
47 2WA2 SAM 0.0003473 0.40277 2.89855
48 5N5D SAM 0.0002873 0.41462 3.09735
49 4A6D SAM 0.0007659 0.45203 3.16901
50 3U31 NAD 0.0006547 0.44713 3.16901
51 2CDU ADP 0.002325 0.43847 3.16901
52 1MUU NAD 0.001007 0.42584 3.16901
53 3L9W GSH 0.000663 0.42501 3.16901
54 3L9W AMP 0.0005875 0.41798 3.16901
55 4RPL FAD 0.009585 0.41488 3.16901
56 4RPL 3UC 0.0112 0.41379 3.16901
57 1VBO MAN 0.00635 0.41823 3.3557
58 1VBO MAN MAN MAN 0.02921 0.40926 3.3557
59 1ZGA SAH 0.0003349 0.4871 3.36134
60 1JJV ATP 0.02166 0.41685 3.39806
61 2AG8 NAP 0.003692 0.41865 3.42205
62 3RKR NAP 0.01698 0.41295 3.43511
63 4POO SAM 0.000001039 0.55366 3.5
64 4AZT SAM 0.000004993 0.55405 3.52113
65 4AZW SAM 0.000005321 0.54672 3.52113
66 1FP1 SAH 0.0001918 0.4932 3.52113
67 1U2Z SAH 0.00008167 0.44911 3.52113
68 1MV8 NAD 0.0009623 0.42661 3.52113
69 3OA2 NAD 0.0009562 0.41894 3.52113
70 4TM3 FAD 0.01546 0.4083 3.52113
71 4BV6 FAD 0.006065 0.40768 3.52113
72 5J60 FAD 0.007967 0.40189 3.52113
73 2CYC TYR 0.04305 0.40072 3.52113
74 5J7X FAD 0.007861 0.40013 3.52113
75 4E13 NAD 0.003454 0.4199 3.53357
76 1XTP SAI 0.000008127 0.54458 3.54331
77 4KXQ APR 0.006126 0.40611 3.55872
78 2BRY FAD 0.003371 0.40921 3.62173
79 3BGD SAH 0.0002317 0.46211 3.84615
80 3BGD PM6 0.0004956 0.43465 3.84615
81 1Q0S SAH 0.000002917 0.53544 3.861
82 5THY SAH 0.0001227 0.48228 3.87324
83 5THZ SAH 0.0001241 0.44105 3.87324
84 3B1F NAD 0.00139 0.43333 3.87324
85 1VJT NAD 0.002221 0.43172 3.87324
86 1RP0 AHZ 0.001036 0.4281 3.87324
87 5T67 JHZ 0.002498 0.42726 3.87324
88 5JGL SAM 0.00008046 0.41803 3.87324
89 5T67 SAH 0.003257 0.41767 3.87324
90 1V6A TRE 0.02284 0.41388 3.87324
91 1V8K ANP 0.01838 0.4112 3.87324
92 3BP1 GUN 0.0269 0.40668 3.87324
93 5XVK SAH 0.00115 0.40568 3.87324
94 3JQ9 AX1 0.03124 0.40328 3.87324
95 4WCX ALA 0.04113 0.40304 3.87324
96 3JQG AX6 0.04293 0.40036 3.87324
97 1I9G SAM 0.000003371 0.54942 3.92857
98 2F1K NAP 0.002205 0.41248 3.94265
99 1VE3 SAM 0.0001333 0.49018 3.96476
100 2HK9 ATR 0.004372 0.44256 4
101 4QM7 GTP 0.02287 0.40641 4.09357
102 5BW4 SAM 0.000007248 0.45558 4.11985
103 4BLW AMP 0.000006634 0.51765 4.22535
104 4BLW SAH 0.00001599 0.488 4.22535
105 3COB ADP 0.009561 0.43524 4.22535
106 2JHP SAH 0.004889 0.42369 4.22535
107 3QPB URA 0.03129 0.40907 4.22535
108 3F8D FAD 0.01835 0.40618 4.22535
109 1DXY NAD 0.003839 0.40303 4.22535
110 4PLG NAI 0.0004213 0.40121 4.22535
111 2HJR APR 0.001757 0.42568 4.26829
112 1I1N SAH 0.000006846 0.50631 4.42478
113 1TE2 PGA 0.03316 0.40812 4.42478
114 2BZG SAH 0.00007225 0.50209 4.57746
115 1X87 NAD 0.0001381 0.47142 4.57746
116 1JQ3 AAT 0.00004816 0.44762 4.57746
117 1WDK NAD 0.0006193 0.44443 4.57746
118 4REP FAD 0.00126 0.4333 4.57746
119 3C3Y SAH 0.002936 0.4264 4.57746
120 2IXB NAD 0.0003964 0.4248 4.57746
121 5JCM FAD 0.01428 0.40741 4.57746
122 5JCM ISD 0.01475 0.40741 4.57746
123 5JCM NAD 0.01475 0.40741 4.57746
124 1SZ2 BGC 0.03136 0.40719 4.57746
125 4XUC SAM 0.0000243 0.49532 4.58716
126 4XUC 43G 0.0000243 0.49532 4.58716
127 2G5C NAD 0.0006082 0.42236 4.62633
128 1Y63 ADP 0.01315 0.41855 4.8913
129 3QOX SAH 0.00002877 0.46386 4.92958
130 1Y8Q ATP 0.000345 0.4512 4.92958
131 5KOK S9T 0.001236 0.42771 4.92958
132 1E1M FAD 0.004716 0.42169 4.92958
133 5KOK SAH 0.000235 0.41844 4.92958
134 1P31 EPU 0.006402 0.41483 4.92958
135 5KOK R9T 0.005211 0.40174 4.92958
136 2NAD NAD 0.006176 0.40113 4.92958
137 5UAV TFB 0.006668 0.4009 4.92958
138 5UAV NDP 0.006668 0.4009 4.92958
139 5O4J SAH 0.005725 0.4013 5.10949
140 5O4J 9KH 0.005725 0.4013 5.10949
141 5O4J PJL 0.00573 0.40011 5.10949
142 5N53 8NB 0.001433 0.48025 5.12821
143 3PT9 SAH 0.000002341 0.56877 5.28169
144 2ZIF SAM 0.000002746 0.55932 5.28169
145 4GQB 0XU 0.0000101 0.51352 5.28169
146 3OND ADN 0.001685 0.43616 5.28169
147 5M67 NAD 0.001941 0.43451 5.28169
148 5M67 3D1 0.002031 0.43369 5.28169
149 5M67 ADE 0.002171 0.43249 5.28169
150 5XVQ SAH 0.001301 0.43108 5.28169
151 2Q0L NAP 0.01547 0.40399 5.28169
152 5FA5 MTA 0.0001855 0.40316 5.28169
153 3NT6 FAD 0.007348 0.40132 5.28169
154 1G60 SAM 0.0000006944 0.58552 5.38462
155 2AOT SAH 0.00001731 0.43719 5.47945
156 2YVJ NAI 0.004507 0.42168 5.50459
157 5ULP KB1 0.0000821 0.47654 5.59701
158 2DPM SAM 0.000002811 0.54701 5.6338
159 2P41 SAH 0.0003363 0.47219 5.6338
160 3NJ4 NAD 0.005303 0.44705 5.6338
161 3NJ4 AFX 0.01296 0.42916 5.6338
162 1JQD SAH 0.0003888 0.42801 5.6338
163 5EZ7 FAD 0.001933 0.42579 5.6338
164 1PN0 IPH 0.003226 0.42533 5.6338
165 1PN0 FAD 0.003075 0.42533 5.6338
166 3GGO ENO 0.004753 0.412 5.6338
167 1JQD HSM 0.002699 0.40903 5.6338
168 3NTD FAD 0.005597 0.40609 5.6338
169 5HTX ADP 0.02801 0.40195 5.6338
170 5E1M SAH 0.000213 0.45797 5.80913
171 5E1M PRO PRO LYS ARG ILE ALA 0.000213 0.45797 5.80913
172 1KYQ NAD 0.0005269 0.46796 5.83942
173 3TKA SAM 0.000008588 0.53195 5.98592
174 1KYZ SAH 0.0005552 0.46243 5.98592
175 2WPF FAD 0.004075 0.44491 5.98592
176 1BZL FAD 0.004426 0.44377 5.98592
177 2WPF WPF 0.009684 0.42932 5.98592
178 3OBT SLB 0.02004 0.4284 5.98592
179 1LVL NAD 0.002426 0.4265 5.98592
180 3UCL FAD 0.005445 0.4261 5.98592
181 3UCL NAP 0.006021 0.4261 5.98592
182 3UCL CYH 0.005445 0.4261 5.98592
183 4XFR CIT 0.02413 0.41335 5.98592
184 4KOA NDP 0.01008 0.40926 5.98592
185 3G2O SAM 0.000007174 0.547 6.33803
186 3OJO NAD 0.001404 0.42971 6.33803
187 4PIO AVI 0.0006893 0.40507 6.33803
188 4PIO SAH 0.0006507 0.40192 6.33803
189 1LSS NAD 0.0004104 0.45971 6.42857
190 4RDN 6MD 0.03254 0.40825 6.58683
191 5HJM MTA 0.000006374 0.54327 6.69014
192 4LWP SAH 0.00002083 0.44838 6.69014
193 4RSL FAD 0.001064 0.43278 6.69014
194 1Z3C SA8 0.0004132 0.42706 6.69014
195 1J49 NAD 0.001298 0.4139 6.69014
196 2Z48 A2G 0.02932 0.41349 6.69014
197 3GCZ SAM 0.00007289 0.42818 6.73759
198 1XCL SAH 0.0007112 0.4139 6.80851
199 3H8V ATP 0.001959 0.43791 6.84932
200 5K7U SAM 0.0008608 0.4539 6.87679
201 3FPF TNA 0.00003101 0.4255 7.04225
202 3FPF MTA 0.00003101 0.4255 7.04225
203 1A5Z NAD 0.004668 0.41111 7.04225
204 3CGD FAD 0.02176 0.40607 7.04225
205 3CGD COA 0.02176 0.40607 7.04225
206 5E9W SAH 0.00004712 0.40395 7.04225
207 2PX8 SAH 0.002491 0.43323 7.0632
208 1O94 ADP 0.002895 0.41362 7.19697
209 2YX1 SFG 0.0000004947 0.47526 7.39437
210 3TKY SAH 0.0001311 0.42892 7.39437
211 1ZH8 NAP 0.001381 0.4175 7.39437
212 4JJF FE9 0.001619 0.41483 7.39437
213 1LDN NAD 0.003449 0.40629 7.39437
214 4JJF N2I 0.001924 0.40336 7.39437
215 1PS9 FAD 0.00791 0.40297 7.39437
216 3S5W FAD 0.002305 0.40079 7.39437
217 5FTW SAH 0.0007033 0.44965 7.42188
218 2JE7 XMM 0.0171 0.42121 7.53138
219 2HMT NAI 0.0005069 0.45182 7.63889
220 3S1S SAH 0.00005537 0.48785 7.74648
221 4PNE SAH 0.0001236 0.43986 7.74648
222 1PL6 NAD 0.001525 0.43518 7.74648
223 5DN9 NAD 0.002746 0.41274 7.74648
224 1V5F FAD 0.01818 0.40287 7.74648
225 2PWY SAH 0.000001069 0.55882 7.75194
226 1F3L SAH 0.00001734 0.51367 8.09859
227 5MPT SAH 0.0001884 0.48346 8.09859
228 2UYQ SAM 0.01178 0.43301 8.09859
229 5G3U FDA 0.004256 0.41089 8.09859
230 2C31 TZD 0.01548 0.40996 8.09859
231 2C31 ADP 0.01504 0.40996 8.09859
232 1NVM NAD 0.001101 0.40235 8.09859
233 3ML1 MGD 0.02452 0.40065 8.09859
234 1XDS SAM 0.0002381 0.49417 8.28877
235 5X62 SAH 0.00003544 0.52156 8.4507
236 5JCA FAD 0.005314 0.41098 8.4507
237 5JCA NDP 0.01364 0.407 8.4507
238 9LDB NAD 0.001614 0.40282 8.4507
239 2DFV NAD 0.003383 0.40249 8.4507
240 9LDT NAD 0.001811 0.4011 8.4507
241 4KRI SAH 0.00008617 0.48887 8.80282
242 5F8F SFG 0.0005583 0.47153 8.80282
243 2Q28 ADP 0.0008979 0.44899 8.80282
244 2A14 SAH 0.001182 0.4363 8.80282
245 1UP7 NAD 0.001826 0.40621 8.80282
246 4JCA CIT 0.0163 0.40737 8.98204
247 3GXO SAH 0.001673 0.44926 9.15493
248 4E3Q PMP 0.02493 0.40451 9.15493
249 5JE8 NAD 0.0002632 0.45226 9.50704
250 3AD8 NAD 0.001922 0.42011 9.50704
251 1R37 NAD 0.002739 0.41401 9.50704
252 1MO9 KPC 0.0167 0.41218 9.50704
253 1MO9 FAD 0.01657 0.41184 9.50704
254 3AD8 PYC 0.01909 0.40315 9.50704
255 3AD8 FAD 0.01909 0.40315 9.50704
256 1LTH NAD 0.006009 0.40071 9.50704
257 1NW5 SAM 0.000002794 0.55899 9.85915
258 3A27 SAM 0.0000804 0.50001 9.85915
259 1FEC FAD 0.001426 0.43824 9.85915
260 1SOW NAD 0.0004948 0.41663 9.85915
261 2XG5 EC5 0.02689 0.40824 9.85915
262 2XG5 EC2 0.02689 0.40824 9.85915
263 3DXY SAM 0.000002334 0.59798 10.0917
264 1KPG SAH 0.00001018 0.52343 10.2113
265 4D7E FAD 0.002179 0.42034 10.2113
266 1ELI PYC 0.002903 0.41758 10.2113
267 3ABI NAD 0.001002 0.4143 10.2113
268 3H2B SAH 0.00005682 0.50159 10.3448
269 3MQ2 SAH 0.0001867 0.48856 10.5505
270 1KPH SAH 0.000009651 0.47397 10.5634
271 3LST SAH 0.0007229 0.47114 10.5634
272 3UOY NAP 0.005823 0.42611 10.5634
273 3UOY FAD 0.005823 0.42611 10.5634
274 3Q3C NAD 0.004683 0.40512 10.5634
275 1JNR FAD 0.02562 0.4014 10.5634
276 2GNB MAN 0.005694 0.44575 10.7143
277 1UKG MMA 0.009308 0.43583 10.7143
278 2GNM MAN 0.00944 0.43505 10.7143
279 2GMM MAN MAN 0.01039 0.42973 10.7143
280 1Q8Q MAN MMA 0.0129 0.42937 10.7143
281 2GN3 MMA 0.01041 0.42888 10.7143
282 2PHT MAN MAN MAN 0.01328 0.42855 10.7143
283 2GN3 MAN 0.01108 0.42735 10.7143
284 2PHU MAN MAN 0.01421 0.4267 10.7143
285 2GND MAN 0.01583 0.42401 10.7143
286 1Q8S MAN MMA 0.01607 0.42341 10.7143
287 1Q8O MAN MMA 0.01896 0.42014 10.7143
288 2PHR MAN MAN 0.02378 0.4136 10.7143
289 2PHF MAN MAN 0.024 0.41339 10.7143
290 2PHW MAN MAN 0.02611 0.41144 10.7143
291 2GND MAN MMA 0.02799 0.40983 10.7143
292 2PHW MAN MAN MAN BMA MAN MAN MAN 0.02864 0.40146 10.7143
293 2PHR MAN MAN BMA MAN 0.03434 0.40114 10.7143
294 1G55 SAH 0.000002998 0.55765 10.9155
295 1TPY SAH 0.000006828 0.53075 10.9155
296 5GWX SAR 0.0001575 0.45744 10.9155
297 5GWX SAM 0.0001575 0.45744 10.9155
298 3LAD FAD 0.0014 0.43466 10.9155
299 4YMH SAH 0.0002222 0.47118 11.25
300 3EVG SAH 0.0001 0.49577 11.2676
301 1QZZ SAM 0.0003481 0.4863 11.2676
302 4USQ FAD 0.004121 0.40697 11.2676
303 4OBW SAM 0.0001068 0.4945 11.284
304 3BXO SAM 0.00004895 0.52698 11.2971
305 3T7S SAM 0.00002561 0.44131 11.6197
306 2PT9 S4M 0.0008858 0.43122 11.6197
307 3SQP FAD 0.02488 0.42622 11.6197
308 1HQL GLA MBG 0.03258 0.4042 11.6732
309 2BOS GLA GAL GLC 0.02945 0.40303 11.7647
310 1U8Z GDP 0.009275 0.40139 11.9048
311 4KRG SAH 0.00005276 0.51365 11.9718
312 4KIB SAH 0.0000008165 0.48344 11.9718
313 1QAN SAH 0.000001694 0.55629 12.2951
314 1BC5 SAH 0.004053 0.41063 12.3239
315 4R6W SAH 0.0007256 0.4087 12.4031
316 3FZG SAM 0.00004491 0.52265 12.5
317 4NEC SAH 0.0001226 0.50228 12.5
318 2I7C AAT 0.0002761 0.4169 12.7208
319 1X14 NAD 0.003361 0.43114 13.0282
320 5FJN BE2 0.004356 0.4173 13.0282
321 5FJN FAD 0.003723 0.4173 13.0282
322 5JE0 SAH 0.00003429 0.48461 13.3603
323 5JE0 AZ8 0.00003429 0.48461 13.3603
324 3JWH SAH 0.00000455 0.44126 13.3641
325 5E72 SAM 0.00000003969 0.55703 13.7324
326 5DXA SFG 0.00002142 0.50493 13.7324
327 5DX8 SFG 0.00002206 0.5044 13.7324
328 5DWQ SFG 0.000006149 0.49286 13.7324
329 5DX0 SFG 0.000008818 0.4922 13.7324
330 3A25 SAM 0.000276 0.47603 13.7324
331 5DX1 SFG 0.0000349 0.4697 13.7324
332 2FKA BEF 0.007099 0.44519 13.9535
333 3FGZ BEF 0.01315 0.42135 14.0625
334 1JG3 ADN 0.000004578 0.55574 14.0845
335 1CF2 NAP 0.0003516 0.43672 14.4366
336 3LKZ SFG 0.0004046 0.46419 14.7887
337 2HNK SAH 0.0006591 0.45086 15.0628
338 1OBB NAD 0.001979 0.42035 15.1408
339 3MB5 SAM 0.000004725 0.5321 15.2941
340 1L3I SAH 0.000002674 0.52684 15.625
341 2O07 MTA 0.00009764 0.46184 15.8451
342 2O07 SPD 0.0001186 0.44763 15.8451
343 5LOG SAH 0.0003703 0.4138 15.8798
344 5MGZ SAH 0.00003732 0.5096 16.1017
345 4DCM SAM 0.00000004215 0.66406 16.1972
346 5GM1 SAH 0.00008899 0.47932 16.1972
347 4N49 SAM 0.0005819 0.45319 16.5493
348 2VDV SAM 0.000003665 0.58074 16.6667
349 5FUI APY 0.01596 0.42842 16.6667
350 3ICT ADP 0.002329 0.45143 17.2535
351 3ICS ADP 0.003565 0.44238 17.2535
352 3OU2 SAH 0.0002766 0.4514 17.4312
353 5MW4 5JU 0.0001291 0.4745 17.9577
354 5E8J SAH 0.00005291 0.52537 18.1818
355 4II2 ATP 0.0001411 0.47966 19.0184
356 3HVJ 705 0.00001485 0.50836 19.7183
357 5FA8 SAM 0.00001908 0.47032 19.8758
358 4DMG SAM 0.000004725 0.58301 20.8651
359 5KVA SAM 0.0003107 0.42394 21.223
360 1DL5 SAH 0.00005093 0.47666 22.1831
361 1UWK NAD 0.0006159 0.45232 22.8873
362 3Q87 SAM 0.00000002482 0.62648 23.5294
363 3IHG FAD 0.001377 0.41219 24.2958
364 1R18 SAH 0.000005598 0.53439 25.9912
Pocket No.: 2; Query (leader) PDB : 1NV8; Ligand: SAM; Similar sites found: 350
This union binding pocket(no: 2) in the query (biounit: 1nv8.bio1) has 31 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1P1C SAH 0.0002203 0.46468 None
2 2WG9 OCA 0.03442 0.40625 None
3 1M2K APR 0.004102 0.40066 0.803213
4 1UAY ADN 0.001591 0.45625 1.23967
5 2PXX SAH 0.00003662 0.51177 1.39535
6 4RDH AMP 0.0009285 0.46273 1.40845
7 4WEI GLC GAL 0.02544 0.40087 1.44404
8 4JK3 NAD 0.0005844 0.43668 1.5444
9 4J4H NAI 0.02081 0.42647 1.5444
10 4J4H 1J1 0.003124 0.42154 1.5444
11 3VSE SAH 0.000005146 0.43489 1.76056
12 2A92 NAI 0.001659 0.40137 1.76056
13 1P77 ATR 0.02384 0.4148 1.83824
14 5U8U FAD 0.002648 0.43692 2.11268
15 2F5Z FAD 0.001238 0.43496 2.11268
16 5MBX FAD 0.002824 0.4292 2.11268
17 5MBX SP5 0.002824 0.4292 2.11268
18 3C6K MTA 0.00181 0.42078 2.11268
19 1ZMD NAI 0.001933 0.41915 2.11268
20 2B9W FAD 0.009076 0.40885 2.11268
21 3LCV SAM 0.0004701 0.41622 2.13523
22 4K28 NAD 0.001965 0.41887 2.23048
23 2EJU SAH 0.00000001982 0.664 2.46479
24 5JJR SAH 0.0001938 0.48456 2.46479
25 1OMO NAD 0.0006124 0.44263 2.46479
26 2YYY NAP 0.001253 0.41774 2.46479
27 4OPC FDA 0.02073 0.41182 2.46479
28 3ZG6 APR 0.006273 0.41009 2.46479
29 2VHW NAI 0.003499 0.40952 2.46479
30 1K0E TRP 0.02721 0.40024 2.46479
31 5CUQ NSC 0.0002847 0.44684 2.62172
32 3P2E SAH 0.00002925 0.51088 2.66667
33 1SQF SAM 0.000006164 0.55191 2.8169
34 1L1E SAH 0.000008278 0.53457 2.8169
35 1V59 NAD 0.0002803 0.49801 2.8169
36 3VYW SAM 0.0001418 0.48126 2.8169
37 1H3F TYE 0.009169 0.43462 2.8169
38 1Q9I TEO 0.002461 0.43324 2.8169
39 3B6R CRN 0.01806 0.42284 2.8169
40 1DJN ADP 0.002499 0.42078 2.8169
41 3LXD FAD 0.003339 0.40917 2.8169
42 2R4J 13P 0.013 0.40017 2.8169
43 2DT5 NAD 0.0007239 0.42682 2.8436
44 5N5D SAM 0.000178 0.42004 3.09735
45 4A6D SAM 0.0008303 0.45203 3.16901
46 3U31 NAD 0.0007126 0.44713 3.16901
47 2CDU ADP 0.002501 0.43847 3.16901
48 3L9W GSH 0.001005 0.42139 3.16901
49 3L9W AMP 0.0007185 0.41798 3.16901
50 4RPL FAD 0.01041 0.41105 3.16901
51 4RPL 3UC 0.01237 0.40969 3.16901
52 1MUU NAD 0.005642 0.40047 3.16901
53 1VBO MAN 0.006683 0.41823 3.3557
54 1VBO MAN MAN MAN 0.03067 0.40926 3.3557
55 1ZGA SAH 0.00006909 0.52159 3.36134
56 2AG8 NAP 0.00398 0.41865 3.42205
57 3RKR NAP 0.018 0.41295 3.43511
58 4POO SAM 0.00000117 0.55366 3.5
59 4AZT SAM 0.000005315 0.5548 3.52113
60 4AZW SAM 0.000005897 0.54672 3.52113
61 1FP1 SAH 0.00009817 0.50851 3.52113
62 1U2Z SAH 0.00002575 0.46127 3.52113
63 1MV8 NAD 0.001066 0.42638 3.52113
64 5J60 FAD 0.001792 0.42541 3.52113
65 3OA2 NAD 0.00117 0.41888 3.52113
66 4TM3 FAD 0.01833 0.40295 3.52113
67 4BV6 FAD 0.007415 0.40174 3.52113
68 2CYC TYR 0.04525 0.40072 3.52113
69 4E13 NAD 0.004322 0.4171 3.53357
70 1XTP SAI 0.000008972 0.54458 3.54331
71 4KXQ APR 0.006783 0.4056 3.55872
72 2BRY FAD 0.004591 0.4014 3.62173
73 3BGD SAH 0.0002363 0.46341 3.84615
74 3BGD PM6 0.0005189 0.43546 3.84615
75 1Q0S SAH 0.000003268 0.53544 3.861
76 5THY SAH 0.00009071 0.48964 3.87324
77 5T67 JHZ 0.0007545 0.44566 3.87324
78 5THZ SAH 0.0001003 0.43917 3.87324
79 5T67 SAH 0.0008833 0.43767 3.87324
80 3B1F NAD 0.001482 0.43365 3.87324
81 1VJT NAD 0.002397 0.43172 3.87324
82 1RP0 AHZ 0.001227 0.42233 3.87324
83 1V6A TRE 0.02408 0.41388 3.87324
84 5JGL SAM 0.00008779 0.41134 3.87324
85 1V8K ANP 0.01948 0.4112 3.87324
86 3JQ9 AX1 0.02724 0.40762 3.87324
87 4WCX ALA 0.04299 0.40304 3.87324
88 3BP1 GUN 0.04084 0.40265 3.87324
89 1I9G SAM 0.000003752 0.54942 3.92857
90 2F1K NAP 0.002344 0.41289 3.94265
91 1VE3 SAM 0.00002176 0.52727 3.96476
92 2HK9 ATR 0.004661 0.44256 4
93 4QM7 GTP 0.02421 0.40641 4.09357
94 5BW4 SAM 0.00000799 0.44801 4.11985
95 4BLW AMP 0.000001819 0.53516 4.22535
96 4BLW SAH 0.00000328 0.50544 4.22535
97 2JHP SAH 0.004603 0.42628 4.22535
98 3QPB URA 0.02946 0.41152 4.22535
99 3COB ADP 0.03879 0.40346 4.22535
100 4PLG NAI 0.0005134 0.40121 4.22535
101 3F8D FAD 0.0217 0.40091 4.22535
102 2HJR APR 0.001907 0.42568 4.26829
103 1I1N SAH 0.000007687 0.49745 4.42478
104 1TE2 PGA 0.03485 0.40812 4.42478
105 2BZG SAH 0.00007901 0.50209 4.57746
106 1X87 NAD 0.0001397 0.47291 4.57746
107 1JQ3 AAT 0.00006074 0.44762 4.57746
108 1WDK NAD 0.0006733 0.44449 4.57746
109 3C3Y SAH 0.001535 0.44025 4.57746
110 4REP FAD 0.001415 0.42842 4.57746
111 2IXB NAD 0.0004799 0.4248 4.57746
112 1SZ2 BGC 0.03306 0.40719 4.57746
113 1D4D SIN 0.03998 0.40275 4.57746
114 5JCM NAD 0.01785 0.40169 4.57746
115 5JCM ISD 0.01785 0.40169 4.57746
116 5JCM FAD 0.01728 0.40169 4.57746
117 3NKS ACJ 0.01881 0.40127 4.57746
118 4XUC SAM 0.00001828 0.49612 4.58716
119 4XUC 43G 0.00001828 0.49612 4.58716
120 2G5C NAD 0.0007302 0.42236 4.62633
121 3QOX SAH 0.000007681 0.47773 4.92958
122 1Y8Q ATP 0.0003778 0.4512 4.92958
123 5KOK S9T 0.001658 0.41984 4.92958
124 1E1M FAD 0.005134 0.41766 4.92958
125 2ZFU SAH 0.0001718 0.41759 4.92958
126 1P31 EPU 0.006865 0.41483 4.92958
127 5KOK SAH 0.0002561 0.41227 4.92958
128 5UAV TFB 0.005078 0.40203 4.92958
129 5N53 8NB 0.001527 0.48025 5.12821
130 3PT9 SAH 0.000002599 0.56877 5.28169
131 2ZIF SAM 0.000003052 0.55932 5.28169
132 4GQB 0XU 0.00001125 0.51352 5.28169
133 5XVQ SAH 0.001414 0.43108 5.28169
134 3OND ADN 0.002189 0.42873 5.28169
135 5M67 3D1 0.002495 0.42729 5.28169
136 5M67 ADE 0.002605 0.42652 5.28169
137 5M67 NAD 0.002682 0.426 5.28169
138 1G60 SAM 0.0000007766 0.58552 5.38462
139 2AOT SAH 0.00001957 0.42915 5.47945
140 2YVJ NAI 0.00484 0.42168 5.50459
141 5ULP KB1 0.00001626 0.50699 5.59701
142 2DPM SAM 0.0000006255 0.57669 5.6338
143 2P41 SAH 0.0003653 0.47219 5.6338
144 3NJ4 NAD 0.006641 0.44014 5.6338
145 1JQD SAH 0.000508 0.42748 5.6338
146 3NJ4 AFX 0.01609 0.42266 5.6338
147 5EZ7 FAD 0.002142 0.42126 5.6338
148 1PN0 IPH 0.00351 0.42121 5.6338
149 1PN0 FAD 0.003344 0.42121 5.6338
150 5DNK SAH 0.000008131 0.41626 5.6338
151 3GGO ENO 0.004126 0.41196 5.6338
152 1JQD HSM 0.003195 0.40758 5.6338
153 5HTX ADP 0.0285 0.40281 5.6338
154 3NTD FAD 0.00622 0.40181 5.6338
155 5E1M PRO PRO LYS ARG ILE ALA 0.0002689 0.45064 5.80913
156 5E1M SAH 0.0002689 0.45064 5.80913
157 1KYQ NAD 0.0005703 0.46796 5.83942
158 3TKA SAM 0.000009517 0.53195 5.98592
159 1KYZ SAH 0.00008537 0.50058 5.98592
160 2WPF FAD 0.004851 0.439 5.98592
161 1BZL FAD 0.005523 0.43697 5.98592
162 2WPF WPF 0.008552 0.42943 5.98592
163 1LVL NAD 0.002621 0.4265 5.98592
164 3UCL CYH 0.006556 0.42021 5.98592
165 3UCL FAD 0.006556 0.42021 5.98592
166 3UCL NAP 0.007746 0.41899 5.98592
167 4XFR CIT 0.02536 0.41335 5.98592
168 4KOA NDP 0.01077 0.40926 5.98592
169 3LE7 ADE 0.01412 0.42605 6.13027
170 3G2O SAM 0.000001623 0.57797 6.33803
171 3OJO NAD 0.001525 0.42971 6.33803
172 4PIO AVI 0.0004109 0.41679 6.33803
173 4PIO SAH 0.0004086 0.41275 6.33803
174 1LSS NAD 0.0004521 0.4595 6.42857
175 4RDN 6MD 0.03425 0.40825 6.58683
176 5HJM MTA 0.000007059 0.54327 6.69014
177 4LWP SAH 0.000003043 0.46844 6.69014
178 4RSL FAD 0.001309 0.42631 6.69014
179 1Z3C SA8 0.0005865 0.42518 6.69014
180 1J49 NAD 0.00149 0.41488 6.69014
181 4JZ8 CIT 0.0363 0.40727 6.69014
182 3GCZ SAM 0.00007971 0.42141 6.73759
183 1XCL SAH 0.0002253 0.43333 6.80851
184 3H8V ATP 0.002112 0.43791 6.84932
185 5K7U SAM 0.0008012 0.45684 6.87679
186 3FPF TNA 0.00001472 0.43878 7.04225
187 3FPF MTA 0.00001472 0.43878 7.04225
188 2XVM SAH 0.00004889 0.4114 7.04225
189 1A5Z NAD 0.005034 0.41111 7.04225
190 5E9W SAH 0.00007039 0.4029 7.04225
191 2PX8 SAH 0.002454 0.43497 7.0632
192 1O94 ADP 0.002845 0.41537 7.19697
193 3IWD M2T 0.009537 0.43598 7.35294
194 2YX1 SFG 0.0000005491 0.46682 7.39437
195 4JJF FE9 0.001769 0.41483 7.39437
196 1ZH8 NAP 0.001509 0.41161 7.39437
197 4JJF N2I 0.002378 0.40298 7.39437
198 3TKY SAH 0.0005906 0.40189 7.39437
199 1LDN NAD 0.003998 0.40122 7.39437
200 1PS9 FAD 0.007821 0.40081 7.39437
201 3S5W FAD 0.002749 0.40079 7.39437
202 5FTW SAH 0.000764 0.44965 7.42188
203 2JE7 XMM 0.01808 0.42121 7.53138
204 2HMT NAI 0.0005524 0.45182 7.63889
205 3S1S SAH 0.00001336 0.51531 7.74648
206 4PNE SAH 0.00002458 0.45828 7.74648
207 1PL6 NAD 0.001617 0.43557 7.74648
208 5DN9 NAD 0.003194 0.40752 7.74648
209 2F5X ASP 0.03789 0.40401 7.74648
210 2PWY SAH 0.000000449 0.5766 7.75194
211 5IL1 SAM 0.007294 0.41365 8
212 1F3L SAH 0.000003262 0.54629 8.09859
213 5MPT SAH 0.0002052 0.48346 8.09859
214 2UYQ SAM 0.01244 0.43301 8.09859
215 5G3U FDA 0.004587 0.40706 8.09859
216 2C31 ADP 0.0182 0.4042 8.09859
217 2C31 TZD 0.01874 0.4042 8.09859
218 1NVM NAD 0.001301 0.40235 8.09859
219 1XDS SAM 0.0002577 0.49417 8.28877
220 5X62 SAH 0.0000388 0.52156 8.4507
221 5JCA FAD 0.005102 0.40922 8.4507
222 5JCA NDP 0.01144 0.40803 8.4507
223 2DFV NAD 0.003566 0.40302 8.4507
224 9LDB NAD 0.001923 0.40282 8.4507
225 9LDT NAD 0.002152 0.4011 8.4507
226 4KRI SAH 0.00001581 0.52243 8.80282
227 5F8F SFG 0.0005647 0.47287 8.80282
228 2Q28 ADP 0.0009728 0.44899 8.80282
229 2A14 SAH 0.001283 0.4363 8.80282
230 1UP7 NAD 0.001987 0.4005 8.80282
231 1JW0 GUA 0.01632 0.42357 8.86076
232 4JCA CIT 0.01707 0.40737 8.98204
233 3GXO SAH 0.001799 0.44926 9.15493
234 4E3Q PMP 0.02638 0.40451 9.15493
235 5JE8 NAD 0.0002812 0.45275 9.50704
236 4CJN QNZ 0.0172 0.42217 9.50704
237 3AD8 NAD 0.001915 0.41741 9.50704
238 1R37 NAD 0.003263 0.40838 9.50704
239 1MO9 KPC 0.02013 0.40648 9.50704
240 1MO9 FAD 0.01988 0.40622 9.50704
241 3AD8 FAD 0.01931 0.40082 9.50704
242 3AD8 PYC 0.01931 0.40082 9.50704
243 1LTH NAD 0.006491 0.40071 9.50704
244 1NW5 SAM 0.000003064 0.55925 9.85915
245 3A27 SAM 0.00008789 0.50001 9.85915
246 1FEC FAD 0.001835 0.43094 9.85915
247 1SOW NAD 0.0005968 0.41663 9.85915
248 2XG5 EC5 0.0282 0.40824 9.85915
249 2XG5 EC2 0.0282 0.40824 9.85915
250 3DXY SAM 0.0000003043 0.64342 10.0917
251 1KPG SAH 0.00001129 0.52343 10.2113
252 4D7E FAD 0.00254 0.41499 10.2113
253 3ABI NAD 0.001199 0.4143 10.2113
254 1ELI PYC 0.003122 0.41369 10.2113
255 3H2B SAH 0.000009203 0.5382 10.3448
256 3MQ2 SAH 0.000203 0.48856 10.5505
257 3LST SAH 0.0001709 0.50272 10.5634
258 1KPH SAH 0.00001136 0.46458 10.5634
259 3UOY NAP 0.007026 0.42019 10.5634
260 3UOY FAD 0.007026 0.42019 10.5634
261 3Q3C NAD 0.005065 0.40512 10.5634
262 2GNB MAN 0.006006 0.44575 10.7143
263 1UKG MMA 0.009817 0.43583 10.7143
264 2GNM MAN 0.009956 0.43505 10.7143
265 2GMM MAN MAN 0.01096 0.42973 10.7143
266 1Q8Q MAN MMA 0.01361 0.42937 10.7143
267 2PHT MAN MAN MAN 0.01403 0.42855 10.7143
268 2GN3 MAN 0.01164 0.42735 10.7143
269 2PHU MAN MAN 0.01498 0.4267 10.7143
270 1Q8S MAN MMA 0.01615 0.42518 10.7143
271 2GND MAN 0.01668 0.42401 10.7143
272 2GN3 MMA 0.01964 0.42398 10.7143
273 1Q8O MAN MMA 0.02 0.42014 10.7143
274 2PHR MAN MAN 0.0251 0.4136 10.7143
275 2PHF MAN MAN 0.02533 0.41339 10.7143
276 2PHW MAN MAN 0.02755 0.41144 10.7143
277 2GND MAN MMA 0.02952 0.40983 10.7143
278 2PHW MAN MAN MAN BMA MAN MAN MAN 0.03028 0.40146 10.7143
279 2PHR MAN MAN BMA MAN 0.03624 0.40114 10.7143
280 1G55 SAH 0.000003331 0.55765 10.9155
281 1TPY SAH 0.000007978 0.52983 10.9155
282 5GWX SAM 0.0001737 0.45744 10.9155
283 5GWX SAR 0.0001737 0.45744 10.9155
284 3LAD FAD 0.001672 0.4287 10.9155
285 4YMH SAH 0.0002357 0.47173 11.25
286 3EVG SAH 0.0001092 0.49577 11.2676
287 1QZZ SAM 0.0003729 0.48648 11.2676
288 4USQ FAD 0.004939 0.40135 11.2676
289 4OBW SAM 0.0001166 0.4945 11.284
290 3BXO SAM 0.00005331 0.52698 11.2971
291 3T7S SAM 0.00002813 0.43396 11.6197
292 2PT9 S4M 0.0009674 0.43122 11.6197
293 3SQP FAD 0.03253 0.41865 11.6197
294 2BOS GLA GAL GLC 0.03092 0.40303 11.7647
295 4KRG SAH 0.00005767 0.51365 11.9718
296 4KIB SAH 0.0000009085 0.47475 11.9718
297 1QAN SAH 0.0000008846 0.57031 12.2951
298 1BC5 SAH 0.005229 0.40742 12.3239
299 5TVF CGQ 0.0326 0.40354 12.3239
300 4R6W SAH 0.0001668 0.43471 12.4031
301 3FZG SAM 0.00004903 0.52265 12.5
302 4NEC SAH 0.0001333 0.50228 12.5
303 2I7C AAT 0.0003463 0.41628 12.7208
304 1X14 NAD 0.003609 0.43114 13.0282
305 5FJN BE2 0.005901 0.40941 13.0282
306 5FJN FAD 0.005047 0.40941 13.0282
307 5JE0 SAH 0.00004317 0.47685 13.3603
308 5JE0 AZ8 0.00004317 0.47685 13.3603
309 3JWH SAH 0.000004994 0.43407 13.3641
310 1LVG ADP 0.01937 0.41961 13.6364
311 5E72 SAM 0.000000008053 0.57143 13.7324
312 5DX8 SFG 0.000004233 0.53607 13.7324
313 5DXA SFG 0.000004383 0.53544 13.7324
314 5DX0 SFG 0.000001784 0.51041 13.7324
315 5DWQ SFG 0.000001234 0.51028 13.7324
316 5DX1 SFG 0.000007074 0.4884 13.7324
317 3A25 SAM 0.0003 0.47603 13.7324
318 2FKA BEF 0.007469 0.44519 13.9535
319 3FGZ BEF 0.01381 0.42135 14.0625
320 1JG3 ADN 0.000005067 0.55574 14.0845
321 1CF2 NAP 0.0003864 0.43008 14.4366
322 3LKZ SFG 0.00046 0.46333 14.7887
323 2HNK SAH 0.0002317 0.47205 15.0628
324 1OBB NAD 0.002149 0.42035 15.1408
325 3MB5 SAM 0.000001429 0.55569 15.2941
326 1L3I SAH 0.000002994 0.52693 15.625
327 2O07 MTA 0.0001082 0.46184 15.8451
328 2O07 SPD 0.0001491 0.44763 15.8451
329 5LOG SAH 0.0003579 0.40998 15.8798
330 5MGZ SAH 0.00004101 0.5096 16.1017
331 4DCM SAM 0.00000001082 0.69415 16.1972
332 5GM1 SAH 0.00001782 0.5101 16.1972
333 4N49 SAM 0.0006327 0.45319 16.5493
334 2VDV SAM 0.000004035 0.58074 16.6667
335 5FUI APY 0.0004943 0.52291 16.6667
336 3ICT ADP 0.002493 0.45143 17.2535
337 3ICS ADP 0.00381 0.44238 17.2535
338 3OU2 SAH 0.0001237 0.46705 17.4312
339 5MW4 5JU 0.00004133 0.4907 17.9577
340 5E8J SAH 0.00005095 0.52793 18.1818
341 4II2 ATP 0.0001544 0.47966 19.0184
342 3HVJ 705 0.000009105 0.51258 19.7183
343 5FA8 SAM 0.000004097 0.48694 19.8758
344 4DMG SAM 0.000005185 0.58301 20.8651
345 5KVA SAM 0.00006944 0.44222 21.223
346 1DL5 SAH 0.00002222 0.49263 22.1831
347 1UWK NAD 0.000759 0.44555 22.8873
348 3Q87 SAM 0.000000006128 0.65417 23.5294
349 3IHG FAD 0.001789 0.41186 24.2958
350 1R18 SAH 0.000006229 0.53439 25.9912
Pocket No.: 3; Query (leader) PDB : 1NV8; Ligand: SAM; Similar sites found: 44
This union binding pocket(no: 3) in the query (biounit: 1nv8.bio2) has 30 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1RYI FAD 0.007292 0.40442 2.46479
2 3GJ8 GDP 0.01813 0.40771 2.71493
3 3GJ4 GDP 0.02016 0.40543 2.71493
4 3GJ5 GDP 0.02113 0.40443 2.71493
5 2XT3 ADP 0.01127 0.43264 2.8169
6 1HE1 AF3 0.02582 0.4117 2.84091
7 2JHF NAD 0.041 0.40982 3.16901
8 1SC6 NAD 0.001111 0.40486 3.16901
9 4DSU BZI 0.0327 0.40682 3.1746
10 1JJV ATP 0.01841 0.42105 3.39806
11 4K91 SIN 0.02633 0.40753 3.52113
12 2YVF NAD 0.01359 0.40707 3.52113
13 2YVF FAD 0.01339 0.40671 3.52113
14 1RZM E4P 0.04182 0.40643 3.52113
15 2G50 ALA 0.03838 0.4029 3.52113
16 2O7B HC4 0.01439 0.40896 3.87324
17 5XVK SAH 0.001408 0.40309 3.87324
18 4JEJ 1GP 0.02449 0.40126 4.09836
19 1DXY NAD 0.004183 0.40156 4.22535
20 5AHS SIN 0.03748 0.404 4.57746
21 3A1I UNU 0.02566 0.40387 4.57746
22 5MRH Q9Z 0.02087 0.41239 4.92958
23 4MOB ADP 0.02901 0.40941 4.92958
24 5UAV NDP 0.004337 0.40838 4.92958
25 1V0O INR 0.01306 0.40091 4.92958
26 5O4J SAH 0.00591 0.40075 5.10949
27 5O4J 9KH 0.00591 0.40075 5.10949
28 2Q0L NAP 0.01626 0.40298 5.28169
29 5FA5 MTA 0.0002313 0.40015 5.28169
30 2V3V MGD 0.02152 0.40368 5.6338
31 3CH5 GDP 0.01567 0.41083 5.76923
32 3OBT SLB 0.0207 0.42961 5.98592
33 2IZ1 ATR 0.001591 0.47698 6.33803
34 3CGD FAD 0.02546 0.40304 7.04225
35 3CGD COA 0.02546 0.40304 7.04225
36 2NCD ADP 0.02499 0.41312 7.39437
37 5BUK FAD 0.009939 0.40163 7.39437
38 1V5F FAD 0.01534 0.40606 7.74648
39 1G8K MGD 0.01883 0.40456 8.09859
40 2RBK VN4 0.04521 0.40318 8.81226
41 3GJ7 GDP 0.01626 0.41004 9.18367
42 2PT9 2MH 0.0008043 0.40174 11.6197
43 1U8Z GDP 0.009778 0.4004 11.9048
44 3ICR FAD 0.007302 0.40039 17.2535
Pocket No.: 4; Query (leader) PDB : 1NV8; Ligand: MEQ; Similar sites found: 26
This union binding pocket(no: 4) in the query (biounit: 1nv8.bio2) has 30 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1JXN MFU 0.04371 0.40069 2.06612
2 3GJ5 GDP 0.02298 0.40263 2.71493
3 1SC6 NAD 0.00128 0.40258 3.16901
4 4DSU BZI 0.0327 0.40682 3.1746
5 1VKF CIT 0.04437 0.40254 3.19149
6 4EE7 PIS 0.006289 0.43863 3.52113
7 4K91 SIN 0.02633 0.40753 3.52113
8 2YVF FAD 0.01301 0.40724 3.52113
9 1RZM E4P 0.04182 0.40643 3.52113
10 2YVF NAD 0.01469 0.40562 3.52113
11 5EVY SAL 0.03642 0.4038 4.22535
12 5AHS SIN 0.03748 0.404 4.57746
13 5MRH Q9Z 0.02087 0.41239 4.92958
14 4MOB ADP 0.02901 0.40941 4.92958
15 2QES ADE 0.03314 0.40121 5.74713
16 3LE7 ADE 0.01763 0.41897 6.13027
17 2IZ1 ATR 0.003873 0.45686 6.33803
18 3IWD M2T 0.01083 0.43747 7.35294
19 2NCD ADP 0.0375 0.40327 7.39437
20 5IL1 SAM 0.002395 0.43399 8
21 4USR FAD 0.005442 0.40099 8.80282
22 2RBK VN4 0.04521 0.40318 8.81226
23 3GJ7 GDP 0.02381 0.40187 9.18367
24 3PFG SAM 0.0273 0.40546 11.6197
25 2PT9 2MH 0.0007983 0.40185 11.6197
26 2O4C NAD 0.004118 0.40327 12.6316
Feedback