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Receptor
PDB id Resolution Class Description Source Keywords
1O72 2.41 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF THE WATER-SOLUBLE STATE OF THE PORE-FORMING CYTOLYSIN STICHOLYSIN II COMPLEXED WITH P HOSPHORYLCHOLINE STOICHACTIS HELIANTHUS CYTOLYSIN PORE-FORMING TOXIN MEMBRANE INTERACTION HEMOLYSIS
Ref.: CRYSTAL AND ELECTRON MICROSCOPY STRUCTURES OF STICHOLYSIN II ACTINOPORIN REVEAL INSIGHTS INTO THE MECHANISM OF MEMBRANE PORE FORMATION STRUCTURE V. 11 1319 2003
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
PC A:1176;
B:1176;
Valid;
Valid;
none;
none;
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184.151 C5 H15 N O4 P C[N+]...
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1O72 2.41 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF THE WATER-SOLUBLE STATE OF THE PORE-FORMING CYTOLYSIN STICHOLYSIN II COMPLEXED WITH P HOSPHORYLCHOLINE STOICHACTIS HELIANTHUS CYTOLYSIN PORE-FORMING TOXIN MEMBRANE INTERACTION HEMOLYSIS
Ref.: CRYSTAL AND ELECTRON MICROSCOPY STRUCTURES OF STICHOLYSIN II ACTINOPORIN REVEAL INSIGHTS INTO THE MECHANISM OF MEMBRANE PORE FORMATION STRUCTURE V. 11 1319 2003
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1443 families.
1 1O72 - PC C5 H15 N O4 P C[N+](C)(C....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1205 families.
1 1O72 - PC C5 H15 N O4 P C[N+](C)(C....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1039 families.
1 1O72 - PC C5 H15 N O4 P C[N+](C)(C....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: PC; Similar ligands found: 3
No: Ligand ECFP6 Tc MDL keys Tc
1 PC 1 1
2 OPE 0.518519 0.680851
3 CH5 0.45 0.84
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1O72; Ligand: PC; Similar sites found with APoc: 11
This union binding pocket(no: 1) in the query (biounit: 1o72.bio2) has 7 residues
No: Leader PDB Ligand Sequence Similarity
1 2DSA HPX 2.85714
2 4Y9T PA1 2.85714
3 5Z7B VNL 2.85714
4 3G4G D71 3.42857
5 1EKO NAP 8.57143
6 4MO2 FAD 9.14286
7 1KOL NAD 9.71429
8 1GQG DCD 10.2857
9 1PBK RAP 12.931
10 2WME NAP 18.8571
11 2DYR PGV 19.6429
Pocket No.: 2; Query (leader) PDB : 1O72; Ligand: PC; Similar sites found with APoc: 4
This union binding pocket(no: 2) in the query (biounit: 1o72.bio1) has 5 residues
No: Leader PDB Ligand Sequence Similarity
1 2I8T GDD 2.39521
2 4TQ3 GPP 12
3 5ZCO PGV 19.6429
4 5Z84 PGV 19.6429
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