-->
Receptor
PDB id Resolution Class Description Source Keywords
1ODI 2.4 Å EC: 2.4.2.28 PURINE NUCLEOSIDE PHOSPHORYLASE FROM THERMUS THERMOPHILUS THERMUS THERMOPHILUS TRANSFERASE NUCLEOSIDE PHOSPHORYLASE ALPHA-BETA PROTEIN ADENOSINE RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE RSGI STRUCTURAL GENOMICS
Ref.: CRYSTAL STRUCTURE OF PURINE NUCLEOSIDE PHOSPHORYLASE FROM THERMUS THERMOPHILUS J.MOL.BIOL. V. 337 1149 2004
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ADN A:1237;
B:1237;
C:1238;
D:1237;
E:1237;
F:1238;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
none;
none;
Kd = 62 uM
267.241 C10 H13 N5 O4 c1nc(...
SO4 A:1236;
B:1236;
C:1236;
C:1237;
D:1236;
E:1236;
F:1236;
F:1237;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
none;
none;
none;
submit data
96.063 O4 S [O-]S...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1ODJ 2.4 Å EC: 2.4.2.28 PURINE NUCLEOSIDE PHOSPHORYLASE FROM THERMUS THERMOPHILUS THERMUS THERMOPHILUS TRANSFERASE NUCLEOSIDE PHOSPHORYLASE ALPHA-BETA PROTEIN GUANOSINE RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE RSGI STRUCTURAL GENOMICS
Ref.: CRYSTAL STRUCTURE OF PURINE NUCLEOSIDE PHOSPHORYLASE FROM THERMUS THERMOPHILUS J.MOL.BIOL. V. 337 1149 2004
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 5 families.
1 1ODI Kd = 62 uM ADN C10 H13 N5 O4 c1nc(c2c(n....
2 1ODJ Kd = 80 uM GMP C10 H13 N5 O5 c1nc2c(n1[....
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 5 families.
1 1ODI Kd = 62 uM ADN C10 H13 N5 O4 c1nc(c2c(n....
2 1ODJ Kd = 80 uM GMP C10 H13 N5 O5 c1nc2c(n1[....
50% Homology Family (45)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 1Z35 - 2FA C10 H12 F N5 O4 c1nc2c(nc(....
2 1Z34 ic50 = 0.42 mM 2FD C10 H12 F N5 O3 c1nc2c(nc(....
3 1Z38 - NOS C10 H12 N4 O5 c1nc2c(n1[....
4 1PR1 Ki = 5 uM FMB C10 H12 N4 O5 C1=Nc2c(n[....
5 1OUM - TAL C12 H16 N4 O4 Cc1c2c(ncn....
6 1PR2 - MDR C11 H14 N4 O3 Cc1c2c(ncn....
7 1PR5 Ki = 120 uM TBN C11 H14 N4 O4 c1cn(c2c1c....
8 1PKE - 2FD C10 H12 F N5 O3 c1nc2c(nc(....
9 1PR6 - XYA C10 H13 N5 O4 c1nc(c2c(n....
10 1PR0 - NOS C10 H12 N4 O5 c1nc2c(n1[....
11 1PK9 - 2FA C10 H12 F N5 O4 c1nc2c(nc(....
12 1OV6 - DBM C12 H16 N4 O4 Cc1c2c(ncn....
13 1PR4 - MTP C11 H14 N4 O4 S CSc1c2c(nc....
14 1PK7 - ADN C10 H13 N5 O4 c1nc(c2c(n....
15 1OVG - MDR C11 H14 N4 O3 Cc1c2c(ncn....
16 1OU4 - 6MP C6 H6 N4 Cc1c2c(nc[....
17 1OTY - 6MP C6 H6 N4 Cc1c2c(nc[....
18 3UT6 - FMC C10 H13 N5 O4 c1nc2c(c(n....
19 1PW7 - RAB C10 H13 N5 O4 c1nc(c2c(n....
20 1K9S - FM2 C11 H16 N5 O4 C[n+]1cnc2....
21 1A69 Ki = 5 uM FMB C10 H12 N4 O5 C1=Nc2c(n[....
22 1VHW - ADN C10 H13 N5 O4 c1nc(c2c(n....
23 5MX4 - HPA C5 H4 N4 O c1[nH]c2c(....
24 5MX6 - HPA C5 H4 N4 O c1[nH]c2c(....
25 5MX8 - HPA C5 H4 N4 O c1[nH]c2c(....
26 6F4X Kd = 10.7 uM FMC C10 H13 N5 O4 c1nc2c(c(n....
27 6F4W Kd = 2.95 uM FMC C10 H13 N5 O4 c1nc2c(c(n....
28 1JDT - MTA C11 H15 N5 O3 S CSC[C@@H]1....
29 1JE1 - GMP C10 H13 N5 O5 c1nc2c(n1[....
30 1JDZ - FMB C10 H12 N4 O5 C1=Nc2c(n[....
31 2AC7 - ADN C10 H13 N5 O4 c1nc(c2c(n....
32 3UAZ - NOS C10 H12 N4 O5 c1nc2c(n1[....
33 3UAY - ADN C10 H13 N5 O4 c1nc(c2c(n....
34 3UAX - NOS C10 H12 N4 O5 c1nc2c(n1[....
35 3UAW - ADN C10 H13 N5 O4 c1nc(c2c(n....
36 1ODI Kd = 62 uM ADN C10 H13 N5 O4 c1nc(c2c(n....
37 1ODJ Kd = 80 uM GMP C10 H13 N5 O5 c1nc2c(n1[....
38 4DAO - ADE C5 H5 N5 c1[nH]c2c(....
39 4DA6 - GA2 C9 H13 N5 O4 c1nc2c(n1C....
40 4DA7 - AC2 C8 H11 N5 O3 c1nc2c(n1C....
41 4DAE - 6CR C10 H12 Cl N5 O4 c1nc2c(n1[....
42 4D9H - ADN C10 H13 N5 O4 c1nc(c2c(n....
43 4D8V - ADE C5 H5 N5 c1[nH]c2c(....
44 4DAB - HPA C5 H4 N4 O c1[nH]c2c(....
45 3U40 - ADN C10 H13 N5 O4 c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ADN; Similar ligands found: 305
No: Ligand ECFP6 Tc MDL keys Tc
1 RAB 1 1
2 ADN 1 1
3 XYA 1 1
4 5N5 0.811321 0.967742
5 5CD 0.796296 0.920635
6 A4D 0.796296 0.967742
7 MTA 0.758621 0.878788
8 EP4 0.754386 0.852941
9 M2T 0.741379 0.828571
10 DTA 0.741379 0.865672
11 AMP 0.709677 0.842857
12 A 0.709677 0.842857
13 3DH 0.704918 0.878788
14 ZAS 0.68254 0.84058
15 LMS 0.68254 0.7375
16 5AD 0.672727 0.854839
17 SRA 0.671875 0.797297
18 6RE 0.671875 0.830986
19 DSH 0.661538 0.842857
20 AOC 0.661538 0.907692
21 7D7 0.660714 0.875
22 ABM 0.651515 0.819444
23 A2D 0.651515 0.84507
24 J7C 0.651515 0.842857
25 A3N 0.651515 0.923077
26 ADP 0.647059 0.84507
27 S4M 0.641791 0.766234
28 GJV 0.641791 0.819444
29 3AM 0.640625 0.828571
30 AN2 0.637681 0.833333
31 BA3 0.632353 0.84507
32 A12 0.632353 0.810811
33 AP2 0.632353 0.810811
34 MAO 0.632353 0.75641
35 Y3J 0.627119 0.828125
36 5AS 0.623188 0.714286
37 AP5 0.623188 0.84507
38 B4P 0.623188 0.84507
39 ATP 0.619718 0.84507
40 HEJ 0.619718 0.84507
41 5X8 0.619718 0.865672
42 AT4 0.614286 0.810811
43 A7D 0.614286 0.909091
44 SON 0.614286 0.786667
45 5FA 0.611111 0.84507
46 AQP 0.611111 0.84507
47 APC 0.611111 0.810811
48 26A 0.606557 0.893939
49 2FA 0.606557 0.924242
50 ADX 0.605634 0.759494
51 AU1 0.605634 0.821918
52 CA0 0.605634 0.821918
53 MHZ 0.605634 0.75641
54 M33 0.605634 0.833333
55 AGS 0.60274 0.8
56 AD9 0.60274 0.821918
57 SAP 0.60274 0.8
58 2AM 0.6 0.842857
59 ACP 0.597222 0.821918
60 SFG 0.597222 0.850746
61 50T 0.597222 0.833333
62 MTP 0.590164 0.852941
63 APR 0.589041 0.84507
64 PRX 0.589041 0.797297
65 AR6 0.589041 0.84507
66 A3G 0.588235 0.938462
67 ACQ 0.586667 0.821918
68 T99 0.586667 0.810811
69 TAT 0.586667 0.810811
70 A3P 0.585714 0.816901
71 SA8 0.581081 0.794521
72 RBY 0.581081 0.810811
73 A5D 0.581081 0.865672
74 ADP PO3 0.581081 0.842857
75 ADV 0.581081 0.810811
76 6MD 0.580645 0.952381
77 1DA 0.580645 1
78 ADQ 0.575 0.847222
79 OVE 0.573529 0.808219
80 SAH 0.573333 0.84058
81 G5A 0.573333 0.714286
82 SAI 0.573333 0.828571
83 A22 0.56962 0.833333
84 ANP 0.565789 0.821918
85 GAP 0.565789 0.821918
86 SAM 0.565789 0.773333
87 NEC 0.565217 0.876923
88 3AD 0.564516 0.951613
89 6YZ 0.564103 0.821918
90 25A 0.5625 0.819444
91 7D5 0.560606 0.780822
92 5AL 0.558442 0.808219
93 AAT 0.558442 0.819444
94 EEM 0.558442 0.773333
95 ADP ALF 0.551282 0.776316
96 ATF 0.551282 0.810811
97 A5A 0.551282 0.719512
98 ALF ADP 0.551282 0.776316
99 CC5 0.55 0.935484
100 A3S 0.547945 0.953125
101 SSA 0.544304 0.73494
102 S7M 0.544304 0.773333
103 ADP VO4 0.544304 0.808219
104 VO4 ADP 0.544304 0.808219
105 SRP 0.544304 0.810811
106 SMM 0.544304 0.74359
107 QQX 0.544118 0.756757
108 S8M 0.54321 0.805556
109 ADP BMA 0.542169 0.847222
110 A2P 0.541667 0.802817
111 3L1 0.539683 0.907692
112 3D1 0.539683 0.907692
113 PAP 0.539474 0.830986
114 VMS 0.5375 0.702381
115 52H 0.5375 0.694118
116 54H 0.5375 0.702381
117 LSS 0.536585 0.678161
118 QQY 0.536232 0.767123
119 ACK 0.536232 0.811594
120 A3T 0.533333 0.968254
121 53H 0.530864 0.694118
122 5CA 0.530864 0.73494
123 TSB 0.530864 0.731707
124 8X1 0.530864 0.689655
125 MAP 0.530864 0.8
126 DAL AMP 0.530864 0.808219
127 OOB 0.52439 0.808219
128 9ZA 0.52439 0.766234
129 8QN 0.52439 0.808219
130 5SV 0.52439 0.75641
131 9ZD 0.52439 0.766234
132 GEK 0.52439 0.805556
133 OAD 0.52381 0.821918
134 9X8 0.52381 0.8
135 25L 0.523256 0.833333
136 PPS 0.518987 0.7375
137 DSZ 0.518072 0.714286
138 AMO 0.518072 0.810811
139 A1R 0.518072 0.813333
140 A3R 0.518072 0.813333
141 0UM 0.518072 0.808219
142 4AD 0.518072 0.8
143 PAJ 0.518072 0.792208
144 NSS 0.518072 0.714286
145 A A 0.517647 0.819444
146 6CR 0.515152 0.910448
147 SP1 0.514286 0.77027
148 RP1 0.514286 0.77027
149 2VA 0.513158 0.938462
150 DLL 0.511905 0.808219
151 AHX 0.511905 0.802632
152 00A 0.511905 0.766234
153 62X 0.511905 0.74359
154 NVA LMS 0.511905 0.670455
155 3OD 0.511628 0.821918
156 PTJ 0.511628 0.75641
157 ME8 0.511628 0.728395
158 7D3 0.506849 0.783784
159 V3L 0.506329 0.819444
160 A6D 0.505882 0.763158
161 LEU LMS 0.505882 0.670455
162 K15 0.505882 0.763158
163 3UK 0.505882 0.797297
164 GSU 0.5 0.694118
165 B5V 0.5 0.786667
166 P5A 0.5 0.681818
167 KAA 0.5 0.689655
168 NVA 2AD 0.5 0.884058
169 PR8 0.5 0.759494
170 CMP 0.5 0.826087
171 LAD 0.5 0.769231
172 ATR 0.5 0.816901
173 5F1 0.5 0.80597
174 2BA 0.5 0.814286
175 WAQ 0.5 0.766234
176 AD3 0.5 1
177 ATP A A A 0.494382 0.830986
178 9K8 0.494253 0.670455
179 JB6 0.494253 0.766234
180 1ZZ 0.494253 0.728395
181 FYA 0.494253 0.808219
182 SXZ 0.494253 0.773333
183 TXA 0.494253 0.810811
184 BIS 0.494253 0.789474
185 NB8 0.494253 0.779221
186 SO8 0.493671 0.924242
187 VRT 0.493671 0.897059
188 IVH 0.493333 0.835616
189 KB1 0.488636 0.783784
190 MYR AMP 0.488636 0.728395
191 2A5 0.487179 0.797297
192 NOC 0.484375 0.903226
193 4UV 0.483516 0.776316
194 9SN 0.483146 0.75641
195 A2R 0.481928 0.833333
196 7D4 0.480519 0.783784
197 FA5 0.477778 0.786667
198 YAP 0.477778 0.776316
199 B5Y 0.477778 0.776316
200 B5M 0.477778 0.776316
201 8PZ 0.477778 0.714286
202 D3Y 0.47619 0.924242
203 AR6 AR6 0.473118 0.819444
204 AFH 0.473118 0.792208
205 YSA 0.472527 0.694118
206 XAH 0.472527 0.75
207 EKK 0.469697 0.923077
208 TBN 0.46875 0.983607
209 3BH 0.46875 0.953125
210 AMP DBH 0.467391 0.821918
211 TYR AMP 0.467391 0.776316
212 101 0.465753 0.780822
213 LAQ 0.463158 0.728395
214 TO1 0.462687 0.952381
215 G3A 0.462366 0.779221
216 7C5 0.462366 0.819444
217 UPA 0.459184 0.813333
218 LPA AMP 0.458333 0.728395
219 G5P 0.457447 0.779221
220 7MD 0.457447 0.772152
221 ARG AMP 0.457447 0.740741
222 4UU 0.457447 0.776316
223 GA7 0.457447 0.835616
224 A A A 0.454545 0.808219
225 EKH 0.454545 0.923077
226 5ID 0.454545 0.923077
227 TAD 0.452632 0.769231
228 4YB 0.452632 0.678161
229 GTA 0.452632 0.75
230 KH3 0.452632 0.776316
231 DQV 0.452632 0.833333
232 3NZ 0.449438 0.884058
233 WSA 0.44898 0.702381
234 OMR 0.44898 0.740741
235 TYM 0.44898 0.786667
236 AHZ 0.447917 0.728395
237 FTU 0.447761 0.923077
238 139 0.445545 0.782051
239 YLP 0.443299 0.731707
240 48N 0.443299 0.779221
241 AFX 0.441176 0.768116
242 ARJ 0.441176 0.857143
243 AV2 0.440476 0.77027
244 DA 0.44 0.756757
245 D5M 0.44 0.756757
246 5J9 0.43956 0.773333
247 UP5 0.438776 0.8
248 NAI 0.438776 0.789474
249 NXX 0.438776 0.810811
250 NAX 0.438776 0.759494
251 6V0 0.438776 0.779221
252 4UW 0.438776 0.746835
253 TXD 0.438776 0.789474
254 DND 0.438776 0.810811
255 NA7 0.438202 0.810811
256 PO4 PO4 A A A A PO4 0.438202 0.802817
257 MZR 0.4375 0.859375
258 V1N 0.43617 0.819444
259 HO4 0.434783 0.952381
260 TXE 0.434343 0.789474
261 649 0.434343 0.662921
262 AF3 ADP 3PG 0.434343 0.746835
263 IMO 0.434211 0.777778
264 3AT 0.433735 0.819444
265 G A A A 0.432692 0.779221
266 8Q2 0.43 0.689655
267 F0P 0.43 0.794521
268 AP0 0.43 0.779221
269 7MC 0.43 0.753086
270 YLC 0.43 0.75
271 YLB 0.43 0.731707
272 4TC 0.43 0.779221
273 SGV 0.428571 0.967742
274 BS5 0.427184 0.674157
275 A4P 0.425743 0.73494
276 IOT 0.421569 0.722892
277 DAT 0.419753 0.76
278 COD 0.419048 0.72619
279 T5A 0.417476 0.731707
280 ADJ 0.417476 0.740741
281 YLA 0.417476 0.731707
282 AS 0.415584 0.717949
283 J1D 0.415094 0.625
284 0XU 0.414634 0.823529
285 CNA 0.413462 0.810811
286 AYB 0.413462 0.722892
287 103 0.413333 0.716216
288 A U 0.411765 0.8
289 80F 0.411215 0.731707
290 GMP 0.410959 0.882353
291 EO7 0.410256 0.702381
292 F2R 0.409524 0.753086
293 GGZ 0.409091 0.7125
294 U A 0.407407 0.766234
295 ITT 0.407407 0.791667
296 A G 0.40566 0.766234
297 BTX 0.40566 0.710843
298 4TA 0.40566 0.719512
299 NAD 0.40566 0.808219
300 AMP NAD 0.40566 0.808219
301 SFB 0.401961 0.709302
302 DZD 0.401869 0.769231
303 U A G G 0.401869 0.766234
304 BT5 0.401869 0.702381
305 DTP 0.4 0.76
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1ODJ; Ligand: GMP; Similar sites found with APoc: 117
This union binding pocket(no: 1) in the query (biounit: 1odj.bio1) has 17 residues
No: Leader PDB Ligand Sequence Similarity
1 5CLO NS8 None
2 1GZF NIR None
3 2FKA BEF None
4 5TWB FAD 0.851064
5 3GD8 GOL 1.34529
6 4GLJ RHB 1.70213
7 4FK7 P34 1.74672
8 1RM0 NAI 2.12766
9 2XIQ MLC 2.12766
10 1XUJ BOZ 2.24215
11 3LGS ADE 2.55319
12 3LGS SAH 2.55319
13 1IYE PGU 2.55319
14 2WOX NDP 2.55319
15 1A2C 34H LEU PRJ OAR 2.55319
16 3IWK NAD 2.55319
17 1Q19 APC 2.55319
18 2CBO TH2 2.6087
19 3VC1 GST 2.97872
20 3VC1 SAH 2.97872
21 5W75 SUC 2.97872
22 4YRY FAD 2.97872
23 3ESS 18N 3.04348
24 1E6E FAD 3.125
25 5DYO FLU 3.30189
26 4YEE 4CQ 3.33333
27 5U3F 7TS 3.40426
28 4FXQ G9L 3.40426
29 6AM8 TRP 3.40426
30 6C5B SAH 3.40426
31 4RT1 C2E 3.57143
32 6EK3 OUL 3.61991
33 1VKF CIT 3.7234
34 2P4S DIH 3.82979
35 1RJW ETF 3.82979
36 4UUG PXG 3.82979
37 2ZXI FAD 4.25532
38 4PIO SAH 4.68085
39 4PIO AVI 4.68085
40 4WCX MET 4.68085
41 4GKV NAD 4.68085
42 2RDE C2E 4.68085
43 3KYG 5GP 5GP 4.84582
44 1GPM AMP 5.10638
45 1YB5 NAP 5.10638
46 3BGD PM6 5.10638
47 4GV4 MEJ 5.10638
48 5YSI NCA 5.26316
49 5IFK HPA 5.53191
50 1PN0 IPH 5.53191
51 1PN0 FAD 5.53191
52 1Q0S SAH 5.53191
53 1CT9 AMP 5.53191
54 2G2Y MLI 5.95745
55 1Y8Q ATP 5.95745
56 3WYJ H78 5.95745
57 4U8P UDP 5.95745
58 5KMS FAD 5.95745
59 5M3E APR 6.06061
60 3G2O SAM 6.80851
61 1B8O IMH 7.23404
62 4GQB 0XU 7.23404
63 1XSE NDP 7.23404
64 5ETJ IM5 7.65957
65 2A0W DIH 7.65957
66 6BQ6 TER 7.65957
67 5G3U ITW 7.65957
68 5G3U FDA 7.65957
69 3K1X DBX 7.69231
70 1SBR VIB 8
71 2JLD ALA GLY GLY ALA ALA ALA ALA ALA 8.08511
72 5I60 67W 8.08511
73 4CE5 PDG 8.08511
74 3H8V ATP 8.08511
75 4R3U 3HC 8.22785
76 4R3U 3KK 8.22785
77 6B2M COA 8.51064
78 2BOS GLA GAL GLC 8.82353
79 2BOS GLA GAL GLC NBU 8.82353
80 3CBC DBS 9.09091
81 1GYY FHC 9.21053
82 1VRP IOM 9.3617
83 1TLG GAL 9.6
84 2BJK NAD 9.78723
85 5KJW 53C 9.78723
86 5OC1 FAD 9.78723
87 4QAR ADE 9.95025
88 1G2O IMH 10.2128
89 1GPE FAD 10.2128
90 5ZJ5 NAI 10.4938
91 1MFI FHC 10.5263
92 1U6R IOM 10.6383
93 4R38 RBF 11.4286
94 5N53 8NB 14.359
95 1KDK DHT 16.3842
96 3P0F BAU 16.5957
97 5EWK P34 20.5
98 1VMK GUN 20.8511
99 1GZ6 NAI 25.9574
100 5TBS ADE 26.8085
101 1ZBQ NAD 27.234
102 1C3X 8IG 27.6596
103 4WKC BIG 28.1633
104 4BMX ADE 28.9362
105 3BL6 FMC 29.5652
106 4FFS BIG 29.7872
107 4TXJ THM 30.2128
108 3DJF BC3 31.9149
109 4WKB TDI 32.3404
110 1ZOS MTM 33.913
111 6AYR BIG 34.8936
112 3KVY R2B 39.1489
113 3KVY URA 39.1489
114 1NW4 IMH 40
115 4YJK URA 40.8511
116 3EUF BAU 45.1064
117 1U1F 183 47.6596
Pocket No.: 2; Query (leader) PDB : 1ODJ; Ligand: GMP; Similar sites found with APoc: 64
This union binding pocket(no: 2) in the query (biounit: 1odj.bio1) has 16 residues
No: Leader PDB Ligand Sequence Similarity
1 5HWV MBN None
2 1J0X NAD 1.70213
3 4YAG NAI 1.70213
4 1RM0 D6P 2.12766
5 1K3T BRZ 2.12766
6 5WP5 SAH 2.12766
7 1OJZ NAD 2.35849
8 4POO SAM 2.5
9 4ZVV GN0 2.55319
10 4ZVV NAD 2.55319
11 4NFE BEN 2.55319
12 5BUK FAD 2.55319
13 5UFN SAH 2.55319
14 5FUB SAH 2.55319
15 1GR0 NAD 2.55319
16 1GTE FAD 2.97872
17 1KYZ SAH 2.97872
18 1KYZ FER 2.97872
19 4LWP SAH 2.97872
20 1SOX MTE 2.97872
21 2BII MTV 2.97872
22 2A9D MTE 2.97872
23 1O9J NAD 2.97872
24 6ACS CIT 3.40426
25 1VKO NAD 3.40426
26 3SSO SAH 3.40426
27 2EWM NAD 3.40426
28 4PXL NAD 3.82979
29 3A4T SFG 3.82979
30 6HOY TSN 3.82979
31 6HOY AR6 3.82979
32 3TKY SAH 3.82979
33 4MSG 2C6 4.14747
34 5KF6 NAD 4.25532
35 4PZ2 NAD 4.25532
36 1WG8 SAM 4.25532
37 1H2B NAJ 4.25532
38 4PAB THG 4.25532
39 3RHJ NAP 4.68085
40 3E5P PPI 4.68085
41 4NEC SAH 4.68085
42 4K26 NDP 4.68085
43 5NWD 9C8 4.71204
44 5THQ NDP 4.77941
45 5IUW NAD 5.10638
46 5IUW IAC 5.10638
47 1FP1 SAH 5.95745
48 5GWT NAD 5.95745
49 5GWT SIN 5.95745
50 5WP4 SAH 6.38298
51 3P7N FMN 6.38298
52 2PLK P3D 6.38298
53 4X60 3XV 7.23404
54 4X60 SFG 7.23404
55 3FPF MTA 9.3617
56 3FPF TNA 9.3617
57 5FWA J7C 9.78723
58 4FZV SAM 11.0638
59 2R5N TPP 13.617
60 2R5N RP5 13.617
61 5Y4R C2E 15.8621
62 2A5F NAD 17.1429
63 5XLY C2E 17.2932
64 6F5Z SAH 26.2295
Pocket No.: 3; Query (leader) PDB : 1ODJ; Ligand: GMP; Similar sites found with APoc: 18
This union binding pocket(no: 3) in the query (biounit: 1odj.bio1) has 18 residues
No: Leader PDB Ligand Sequence Similarity
1 5O0Z 9GB None
2 3SAO DBH None
3 2XIQ 5AD 2.12766
4 1LVL FAD 2.12766
5 4B2Z P5S 2.55319
6 5MRH Q9Z 2.97872
7 6B5G NAD 2.97872
8 6B5G CQY 2.97872
9 1WB4 SXX 3.40426
10 3WD6 GSH 3.40426
11 1RL4 BL5 4.25532
12 1W6P NDG GAL 4.47761
13 2WSB NAD 6.38298
14 4XYB NDP 7.23404
15 3A16 PXO 9.78723
16 5XWV NDP 10.6383
17 2UYQ SAM 11.4894
18 3H0L ADP 13.8298
Pocket No.: 4; Query (leader) PDB : 1ODJ; Ligand: GMP; Similar sites found with APoc: 25
This union binding pocket(no: 4) in the query (biounit: 1odj.bio1) has 16 residues
No: Leader PDB Ligand Sequence Similarity
1 5LX6 78P None
2 5GM1 SAH 1.70213
3 1F0X FAD 2.12766
4 1Q19 SSC 2.55319
5 3S1S SAH 3.40426
6 5XNC MTA 3.40426
7 2IMP NAI 3.40426
8 4I3V NAD 3.82979
9 3OU2 SAH 4.12844
10 3X0D SAH 4.68085
11 1PVN MZP 5.10638
12 3BGD SAH 5.10638
13 2J0B UDP 5.10638
14 5U5G 7VD 5.10638
15 2XVF FAD 5.10638
16 5FLJ QUE 5.91398
17 3TLJ SAH 5.95745
18 2XTS MTE 6.34146
19 1ZEM NAD 6.38298
20 1JGT CMA 7.65957
21 1JGT APC 7.65957
22 3DAA PDD 9.78723
23 5WA0 MSS 14.4681
24 2E7Z MGD 18.2979
25 2YQS UD1 18.2979
Pocket No.: 5; Query (leader) PDB : 1ODJ; Ligand: GMP; Similar sites found with APoc: 9
This union binding pocket(no: 5) in the query (biounit: 1odj.bio1) has 16 residues
No: Leader PDB Ligand Sequence Similarity
1 5WGR FAD 1.70213
2 4YNU FAD 2.12766
3 1KY8 NAP 2.55319
4 2NXE SAM 2.97872
5 5DN9 NAD 3.40426
6 2BZG SAH 4.31034
7 2ZMF CMP 4.7619
8 4DEC UDP 5.53191
9 4DEC 3PG 5.53191
Pocket No.: 6; Query (leader) PDB : 1ODJ; Ligand: GMP; Similar sites found with APoc: 2
This union binding pocket(no: 6) in the query (biounit: 1odj.bio1) has 16 residues
No: Leader PDB Ligand Sequence Similarity
1 2EFJ SAH 4.25532
2 6CC0 EWM 8.51064
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