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Receptor
PDB id Resolution Class Description Source Keywords
1OFZ 1.5 Å NON-ENZYME: BINDING CRYSTAL STRUCTURE OF FUNGAL LECTIN: SIX-BLADED BETA-PROPELLER FOLD AND NOVEL FUCOSE RECOGNITION MODE FOR A LEURIA AURANTIA LECTIN ALEURIA AURANTIA SUGAR-BINDING PROTEIN LECTIN AAL FUCOSE ALEURIA AURANTIA LECTIN
Ref.: CRYSTAL STRUCTURE OF FUNGAL LECTIN: SIX-BLADED {BETA}-PROPELLER FOLD AND NOVEL FUCOSE RECOGNITION MODE FOR ALEURIA AURANTIA LECTIN J.BIOL.CHEM. V. 278 27059 2003
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
FUC A:1316;
A:1318;
B:1314;
B:1316;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
submit data
164.156 C6 H12 O5 C[C@H...
FUL A:1313;
A:1314;
A:1315;
A:1317;
B:1313;
B:1315;
B:1317;
B:1318;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
none;
none;
none;
none;
Kd = 24.1 uM
164.156 C6 H12 O5 C[C@H...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1OFZ 1.5 Å NON-ENZYME: BINDING CRYSTAL STRUCTURE OF FUNGAL LECTIN: SIX-BLADED BETA-PROPELLER FOLD AND NOVEL FUCOSE RECOGNITION MODE FOR A LEURIA AURANTIA LECTIN ALEURIA AURANTIA SUGAR-BINDING PROTEIN LECTIN AAL FUCOSE ALEURIA AURANTIA LECTIN
Ref.: CRYSTAL STRUCTURE OF FUNGAL LECTIN: SIX-BLADED {BETA}-PROPELLER FOLD AND NOVEL FUCOSE RECOGNITION MODE FOR ALEURIA AURANTIA LECTIN J.BIOL.CHEM. V. 278 27059 2003
Members (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 510 families.
1 1OFZ Kd = 24.1 uM FUL C6 H12 O5 C[C@H]1[C@....
2 1IUC - FUL C6 H12 O5 C[C@H]1[C@....
3 1IUB - FUL C6 H12 O5 C[C@H]1[C@....
4 5MXC - MFU C7 H14 O5 C[C@H]1[C@....
70% Homology Family (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 391 families.
1 1OFZ Kd = 24.1 uM FUL C6 H12 O5 C[C@H]1[C@....
2 1IUC - FUL C6 H12 O5 C[C@H]1[C@....
3 1IUB - FUL C6 H12 O5 C[C@H]1[C@....
4 5MXC - MFU C7 H14 O5 C[C@H]1[C@....
50% Homology Family (9)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 298 families.
1 4D4U Kd = 91.9 uM FUC C6 H12 O5 C[C@H]1[C@....
2 4AGI - SFU C7 H14 O4 Se C[C@H]1[C@....
3 5EO8 - TFU C7 H14 O4 Se C[C@H]1[C@....
4 5H47 - FSW C8 H16 O4 Se C[C@H]1[C@....
5 5EO7 - SFU C7 H14 O4 Se C[C@H]1[C@....
6 1OFZ Kd = 24.1 uM FUL C6 H12 O5 C[C@H]1[C@....
7 1IUC - FUL C6 H12 O5 C[C@H]1[C@....
8 1IUB - FUL C6 H12 O5 C[C@H]1[C@....
9 5MXC - MFU C7 H14 O5 C[C@H]1[C@....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: FUC; Similar ligands found: 9
No: Ligand ECFP6 Tc MDL keys Tc
1 FCB 1 1
2 FUC 1 1
3 FCA 1 1
4 XXR 1 1
5 G6D 1 1
6 RAM 1 1
7 RM4 1 1
8 FUL 1 1
9 FUF 0.424242 0.846154
Ligand no: 2; Ligand: FUL; Similar ligands found: 9
No: Ligand ECFP6 Tc MDL keys Tc
1 FCB 1 1
2 FUC 1 1
3 FCA 1 1
4 XXR 1 1
5 G6D 1 1
6 RAM 1 1
7 RM4 1 1
8 FUL 1 1
9 FUF 0.424242 0.846154
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1OFZ; Ligand: FUL; Similar sites found with APoc: 39
This union binding pocket(no: 1) in the query (biounit: 1ofz.bio1) has 9 residues
No: Leader PDB Ligand Sequence Similarity
1 2E1A MSE None
2 4KWD JF2 0.961538
3 4O1F THG 1.72414
4 1OS7 AKG 2.12014
5 4A62 ANP 2.24359
6 5WS9 ATP 2.24359
7 4LSJ LSJ 2.32558
8 2GQS C2R 2.53165
9 5I34 IMP 2.5641
10 1DNP FAD 2.88462
11 6C4A PYR 2.88462
12 5UL5 PLM 2.88462
13 5UL5 8D7 2.88462
14 4RSE PLM 2.88462
15 3VOI RCB 3.20513
16 3KRU FMN 3.20513
17 4DMG SAM 3.52564
18 5W7C DAO FTT 3.59712
19 5WYF ILP 4.48718
20 4M26 AKG 4.48718
21 1LFO OLA 4.6875
22 4D42 W0I 4.96454
23 4D42 NAP 4.96454
24 3AD8 PYC 5.05051
25 3AD8 FAD 5.05051
26 3IHG VAK 5.12821
27 1LYB IVA VAL VAL STA ALA STA 6.18557
28 1WKR IVA VAL VAL STA ALA STA 6.41026
29 1Q6O LG6 6.48148
30 3LDW IPE 6.73077
31 1QVJ RP5 7.19178
32 5ZM4 9FU 7.51634
33 5ZM4 AKG 7.51634
34 2J4D FAD 7.69231
35 5I7S NAD 11.2319
36 5I7S E9P 11.2319
37 4U63 FAD 12.5
38 3ZDS M8O 13.7821
39 3ZDS OMD 13.7821
Pocket No.: 2; Query (leader) PDB : 1OFZ; Ligand: FUL; Similar sites found with APoc: 148
This union binding pocket(no: 2) in the query (biounit: 1ofz.bio1) has 12 residues
No: Leader PDB Ligand Sequence Similarity
1 5UBG PRT None
2 3N1S 5GP None
3 4OH4 ANP 1.28205
4 5LPZ ADP 1.28205
5 5DEY 59T 1.3468
6 2PA4 UPG 1.60256
7 6F3G CJN 1.69492
8 5UQK U2F 1.92308
9 3NW7 LGV 1.9544
10 1XG4 ICT 2.0339
11 3N0Y APC 2.23464
12 4OUE IPT 2.24359
13 5V2J UDP 2.24359
14 3OTH CLJ 2.24359
15 5V2J 7WV 2.24359
16 3EKK GS2 2.28013
17 4P25 FUC GAL NAG FUC 2.31788
18 2C91 NAP 2.36686
19 3O0Q TTP 2.5641
20 4Z87 5GP 2.5641
21 5GM5 CBI 2.72727
22 5DRB 5FJ 2.74914
23 1BZY IMU 2.76498
24 5YJI SAH 2.8169
25 4N9I PCG 2.85714
26 1VLJ NAP 2.88462
27 1PVN MZP 2.88462
28 5EFQ ADP 2.98507
29 1M1B SPV 3.05085
30 3A6T 8OG 3.10078
31 2JIG PD2 3.125
32 1J5P NAD 3.16206
33 3H7R NAP 3.20513
34 2ZYI STE 3.20513
35 4NST ADP 3.20513
36 1XAJ CRB 3.20513
37 4NW6 2NS 3.20513
38 4IX4 ADP 3.20513
39 1YNQ NDP 3.20513
40 2YFO GLA 3.20513
41 2YFO GAL 3.20513
42 5ABF XRJ 3.20513
43 1BYG STU 3.23741
44 3M0J OAF 3.25733
45 5DQ8 FLF 3.33333
46 2JEN GLC GLC BGC XYS BGC XYS 3.44828
47 6EXF LYS 3.52564
48 2C6Q NDP 3.52564
49 5J60 FAD 3.52564
50 3MTW M3R 3.52564
51 3H7U NAP 3.52564
52 6CUZ FEV 3.52564
53 3PUR 2HG 3.52564
54 5W7B PA1 PO4 FTT FTT GCS FTT PO4 KDO MYR 3.5461
55 5XVG 8FX 3.75427
56 2DUA OXL 3.7931
57 4JD3 PLM 3.84615
58 4JD3 COA 3.84615
59 6MPT C30 3.84615
60 2ZRU FMN 3.84615
61 4UXL 5P8 3.84615
62 4J25 OGA 3.93013
63 1H5R G1P 4.09556
64 4XB2 NDP 4.16667
65 4XB2 HSE 4.16667
66 5TPR NAD 4.16667
67 5T79 NDP 4.16667
68 1HYH NAD 4.20712
69 3ZS7 ATP 4.33333
70 4UXH T5A 4.34783
71 1UU6 BGC BGC BGC BGC 4.46429
72 5BV3 M7G 4.48718
73 1OJ7 NZQ 4.48718
74 2ZB4 5OP 4.48718
75 2ZB4 NAP 4.48718
76 1V7C HEY 4.48718
77 1OPK P16 4.48718
78 1CX4 CMP 4.59016
79 2ZMF CMP 4.7619
80 5CYV WCA 4.79452
81 2PYW ADP 4.80769
82 3GNI ATP 4.80769
83 2JLD AG1 4.80769
84 1ERB ETR 4.91803
85 6CGD GNP 4.91803
86 5WRJ A3P 4.9505
87 5TO8 7FM 4.96454
88 5IXH OTP 4.96894
89 4AG8 AXI 5.12821
90 3VHE 42Q 5.12821
91 1VA6 ADP 5.12821
92 5I8T LAC 5.58659
93 2BGS NDP 5.76923
94 4CYD CMP 5.77778
95 3N8K D1X 5.81395
96 5K52 OCD 6.03774
97 2HZQ STR 6.32184
98 2CJF RP4 6.36943
99 4A4X JUP 6.45161
100 5OO5 UUA 6.45161
101 5JE0 SAH 6.47773
102 5JE0 AZ8 6.47773
103 3TMK T5A 6.48148
104 3B8I OXL 6.62021
105 1O4T OXL 6.76692
106 1M3U KPL 6.81818
107 3KC1 2T6 6.82493
108 2XB8 XNW 6.84932
109 5YGE GLU 6.89655
110 5H5O PCG 6.97674
111 4P42 PEE 7.05128
112 3JUK UPG 7.11744
113 2OJW ADP 7.37179
114 5D85 P1T 7.37179
115 5D85 FLC 7.37179
116 3VC3 C6P 7.55814
117 4B1M FRU FRU 7.56757
118 5XQW 8EU 7.58294
119 4XF6 INS 7.69231
120 4XF6 ADP 7.69231
121 4XF6 LIP 7.69231
122 4P53 NAI 8.01282
123 1DQS CRB 8.33333
124 1WD4 AHR 8.33333
125 1SMR PIV HIS PRO PHE HIS LPL TYR TYR SER 8.65385
126 5HV0 AKG 8.75576
127 1UWC FER 8.81226
128 4URF NAD 8.87097
129 4KCT PYR 8.97436
130 2F7A BEZ 9.05172
131 1IYK MIM 9.61539
132 4IMG NGF 10.2389
133 4BMO FMN 10.5769
134 2XN2 GLA 10.5769
135 1QD1 FON 11.2179
136 4CCN OGA 11.4286
137 5EYP GDP 11.8343
138 4ITM ATP 13.6508
139 1IIU RTL 14.3678
140 2XD9 XD9 14.3713
141 4B1X LAB 15.3846
142 5ZZB LAB 15.3846
143 5ZZA LAB 15.3846
144 2V92 AMP 18.4713
145 2V92 ATP 18.4713
146 2OBD 2OB 19.8718
147 4Y8D 49J 21.4286
148 2GJ5 VD3 22.8395
Pocket No.: 3; Query (leader) PDB : 1OFZ; Ligand: FUL; Similar sites found with APoc: 28
This union binding pocket(no: 3) in the query (biounit: 1ofz.bio1) has 8 residues
No: Leader PDB Ligand Sequence Similarity
1 5NCJ SIN 1.49254
2 5JNN 6LM 1.57895
3 3WBF NAP 2.29508
4 5WSY 7UC 2.31214
5 3E85 BSU 2.53165
6 3A76 SPD 2.84091
7 2G50 PYR 2.88462
8 4QIJ 1HA 3.52564
9 5OX6 A1Z 3.57143
10 5L9B AKG 3.57143
11 5L9V OGA 3.57143
12 1FLM FMN 4.09836
13 3A7R LAQ 4.16667
14 1OAA OAA 4.6332
15 3A2Q ACA ACA 5.76923
16 6A5Y 9R0 5.88235
17 5FKP 6UL 6.06061
18 5NIU 8YZ 7.03125
19 1MJJ HAL 7.30594
20 1MH5 HAL 7.30594
21 5IQT AKG 7.37179
22 5IQT 6CU 7.37179
23 1BTN I3P 7.54717
24 3DLG GWE 8.01282
25 4IAW LIZ 9.04255
26 3I53 SAH 9.33735
27 5IXG OTP 9.46746
28 1M5B BN1 25.4753
Pocket No.: 4; Query (leader) PDB : 1OFZ; Ligand: FUC; Similar sites found with APoc: 143
This union binding pocket(no: 4) in the query (biounit: 1ofz.bio1) has 12 residues
No: Leader PDB Ligand Sequence Similarity
1 3WHB DCC None
2 3N1S 5GP None
3 5UBG PRT None
4 2IGA XX2 0.961538
5 5LPZ ADP 1.28205
6 4OH4 ANP 1.28205
7 5GZ9 ANP 1.31148
8 4ZAH T5K 1.60256
9 6F3G CJN 1.69492
10 5UQK U2F 1.92308
11 1Q19 SSC 1.92308
12 1XG4 ICT 2.0339
13 3N0Y APC 2.23464
14 5Z6T NAP 2.24359
15 3OTH CLJ 2.24359
16 4OUE IPT 2.24359
17 3EKK GS2 2.28013
18 3BU5 ATP 2.28758
19 4FN4 NAD 2.3622
20 2C91 NAP 2.36686
21 3RGA LSB 2.4735
22 3O0Q TTP 2.5641
23 4Z87 GDP 2.5641
24 4ITU NAI 2.60223
25 5GP0 GPP 2.68456
26 1QIN GIP 2.73224
27 3PXP MYR 2.73973
28 5DRB 5FJ 2.74914
29 4N9I PCG 2.85714
30 1PVN MZP 2.88462
31 6C4A PYR 2.88462
32 3WXL ADP 2.88462
33 5EFQ ADP 2.98507
34 1M1B SPV 3.05085
35 3A6T 8OG 3.10078
36 5VC5 96M 3.11419
37 2JIG PD2 3.125
38 1J5P NAD 3.16206
39 4XAC AKG 3.1746
40 3H7R NAP 3.20513
41 1XAJ CRB 3.20513
42 2YFO GAL 3.20513
43 2YFO GLA 3.20513
44 5XDT MB3 3.24675
45 5AX9 4KT 3.24675
46 5DQ8 FLF 3.33333
47 2ZCQ B65 3.41297
48 2JEN GLC GLC BGC XYS BGC XYS 3.44828
49 6EXF LYS 3.52564
50 2C6Q NDP 3.52564
51 3F3E LEU 3.52564
52 5J60 FAD 3.52564
53 5W7B PA1 PO4 FTT FTT GCS FTT PO4 KDO MYR 3.5461
54 4H2D FMN 3.63636
55 2A8Y MTA 3.7037
56 2DUA OXL 3.7931
57 4JD3 PLM 3.84615
58 4JD3 COA 3.84615
59 5W7D MYR 3.84615
60 6MPT C30 3.84615
61 2ZRU FMN 3.84615
62 2PUL ACP 3.84615
63 4UXL 5P8 3.84615
64 4J25 OGA 3.93013
65 1H74 ADP 4.05405
66 5TPR NAD 4.16667
67 1UU6 BGC BGC BGC BGC 4.46429
68 5BV3 M7G 4.48718
69 1OJ7 NZQ 4.48718
70 2ZB4 5OP 4.48718
71 2ZB4 NAP 4.48718
72 1V7C HEY 4.48718
73 1OPK P16 4.48718
74 1CX4 CMP 4.59016
75 1LFO OLA 4.6875
76 2ZMF CMP 4.7619
77 1F74 NAY 4.77816
78 5CYV WCA 4.79452
79 2PYW ADP 4.80769
80 3GNI ATP 4.80769
81 2JLD AG1 4.80769
82 1ERB ETR 4.91803
83 6CGD GNP 4.91803
84 5WRJ A3P 4.9505
85 5TO8 7FM 4.96454
86 5IXH OTP 4.96894
87 4AG8 AXI 5.12821
88 3VHE 42Q 5.12821
89 1VA6 ADP 5.12821
90 3VDB 149 5.44872
91 5I8T LAC 5.58659
92 1I1N SAH 5.75221
93 2BGS NDP 5.76923
94 5DXT 5H5 5.76923
95 1S8G DAO 5.78512
96 3N8K D1X 5.81395
97 1GT6 OLA 5.94796
98 4M52 FAD 6.08974
99 2HZQ STR 6.32184
100 2CJF RP4 6.36943
101 4A4X JUP 6.45161
102 3TMK T5A 6.48148
103 3B8I OXL 6.62021
104 1O4T OXL 6.76692
105 1M3U KPL 6.81818
106 2XB8 XNW 6.84932
107 5H5O PCG 6.97674
108 4P42 PEE 7.05128
109 5K21 6QF 7.0922
110 1QVJ RP5 7.19178
111 2YIP YIO 7.24638
112 2OJW ADP 7.37179
113 1VHD NAP 7.37179
114 4B1M FRU FRU 7.56757
115 5XQW 8EU 7.58294
116 4XF6 ADP 7.69231
117 4XF6 INS 7.69231
118 4XF6 LIP 7.69231
119 4WN5 MVC 7.82609
120 4P53 NAI 8.01282
121 1DQS CRB 8.33333
122 5HV0 AKG 8.75576
123 1UWC FER 8.81226
124 4URF NAD 8.87097
125 3AFN NAP 8.91473
126 4KCT PYR 8.97436
127 2F7A BEZ 9.05172
128 2GRU NAD 9.29487
129 1IYK MIM 9.61539
130 4IMG NGF 10.2389
131 2XN2 GLA 10.5769
132 1QD1 FON 11.2179
133 4CCN OGA 11.4286
134 3OBT SLB 11.859
135 5LRT ADP 12.5
136 4ITM ATP 13.6508
137 1IIU RTL 14.3678
138 2XD9 XD9 14.3713
139 5DWQ SFG 15
140 4NG2 OHN 16.8478
141 2V92 AMP 18.4713
142 1N62 MCN 19.2771
143 4Y8D 49J 21.4286
Pocket No.: 5; Query (leader) PDB : 1OFZ; Ligand: FUC; Similar sites found with APoc: 237
This union binding pocket(no: 5) in the query (biounit: 1ofz.bio1) has 13 residues
No: Leader PDB Ligand Sequence Similarity
1 6BU0 IHP None
2 1AV5 AP2 None
3 5WA9 9ZD None
4 3TCT 3MI None
5 4OFG PCG None
6 1XRO LEU 1.02389
7 3OZ2 OZ2 1.28205
8 2YGN PCF 1.28205
9 6BQ6 TER 1.28205
10 5A6N U7E 1.41343
11 4INI AMP 1.53846
12 1W5T ANP 1.60256
13 3Q60 ATP 1.60256
14 2VPQ ANP 1.60256
15 2QZX IVA VAL VAL STA ALA STA 1.60256
16 6EZ6 C5Z 1.60256
17 3B1Q NOS 1.60256
18 1PN4 HDC 1.78571
19 4UWJ 7L5 1.92308
20 4UWJ MYA 1.92308
21 3ILR SGN IXD 1.92308
22 3H5N ATP 1.92308
23 4AZW ATP 1.92308
24 1EB1 ASP TYR GLU PRO ILE PRO GLU GLU ALA PHE 1.94553
25 3NW7 LGV 1.9544
26 1O5Q PYR 1.96721
27 1JQ3 AAT 2.02703
28 1J3R 6PG 2.10526
29 1IA9 ANP 2.14286
30 2TPS TPS 2.20264
31 5K4W NAI 2.24359
32 2GVJ DGB 2.24359
33 4EVQ PHB 2.24359
34 5CUQ NSC 2.24719
35 3ORK AGS 2.2508
36 4NS0 PIO 2.25564
37 4XDA ADP 2.26537
38 2GQS ADP 2.53165
39 3E85 BSU 2.53165
40 2GQR ADP 2.53165
41 5MW8 ATP 2.5641
42 1OLM VTQ 2.5641
43 4EIL NDP 2.5641
44 5KBF CMP 2.65781
45 2AMV BIN 2.88462
46 4FFG LBS 2.88462
47 2G50 PYR 2.88462
48 3B99 U51 2.88462
49 4ZL4 4PK 2.88462
50 4U03 GTP 2.88462
51 5JKG 6LF 2.89389
52 2CSN CKI 3.0303
53 1ZZ7 S0H 3.0303
54 4H69 10Y 3.09278
55 6FE1 V14 3.11284
56 5N87 N66 3.20513
57 3HMO STU 3.20513
58 3C6K MTA 3.20513
59 4NW6 2NS 3.20513
60 3PQB VGP 3.20513
61 3C6K SPD 3.20513
62 5LI9 ACP 3.20513
63 5W0N UPU 3.20513
64 4FAJ LEU VAL THR LEU VAL PHE VAL 3.20513
65 4ZDC CO8 3.20513
66 1RRM APR 3.20513
67 1JS3 PLP 142 3.20513
68 5K2M ADP 3.2967
69 5EW9 5VC 3.32103
70 2CM4 RCL 3.33333
71 5H5A 6OU 3.33333
72 6CLV 6MB 3.43643
73 1QY1 PRZ 3.44828
74 5YU3 PRO 3.52564
75 5YU3 NAD 3.52564
76 5ZTN CUR 3.52564
77 4JTA NAP 3.52564
78 5XVG 8FX 3.75427
79 4TO8 FLC 3.76712
80 4XCB AKG 3.83142
81 4XCB HY0 3.83142
82 2WSA MYA 3.84615
83 2WSA 646 3.84615
84 2Q7D ANP 3.84615
85 5TT6 ATP 3.84615
86 4WBD CIT 3.84615
87 5EH0 5NW 3.87597
88 2YC5 6BC 3.94737
89 1B8U OAA 3.95137
90 4LXH C1E 3.97112
91 2C49 ADN 3.97351
92 4GJ3 0XP 3.97351
93 5I0U DCY 4
94 5ML3 DL3 4.02685
95 4RFM 3P6 4.13534
96 3FW3 ETS 4.13534
97 5IH9 6BF 4.16667
98 1PZ1 NAP 4.16667
99 1JQN DCO 4.16667
100 4IZY 1J2 4.16667
101 3FD5 AP2 4.16667
102 3PG7 PTY 4.29688
103 3GZ8 APR 4.32099
104 5RHN 8BR 4.34783
105 3M3E GAL A2G NPO 4.34783
106 3AJH BL3 4.43548
107 2E5A LAQ 4.48718
108 1E4E ADP 4.48718
109 3FW4 CAQ 4.49438
110 5J75 6GQ 4.54545
111 2HKA C3S 4.61538
112 5WO4 B7V 4.63576
113 3KP6 SAL 4.63576
114 2YG2 S1P 4.65116
115 2YG2 FLC 4.65116
116 2GC0 PAN 4.78723
117 4P7X YCP 4.79452
118 4P7X AKG 4.79452
119 5G3U ITW 4.80769
120 4L9Z COA 4.80769
121 4L9Z OXL 4.80769
122 5KY3 GFB 4.80769
123 4MOB COA 4.80769
124 2A1L PCW 4.81482
125 3P7N FMN 5.03876
126 5EQY 5RA 5.12821
127 6FL8 TIY 5.12821
128 6FL8 ADP 5.12821
129 1VA6 P2S 5.12821
130 3UDZ ADP 5.12821
131 3ZOK NAD 5.12821
132 1YKD CMP 5.12821
133 5NKB 8ZT 5.22876
134 3BJK CIT 5.22876
135 5KWY C3S 5.26316
136 2YGO PCF 5.31915
137 3CF6 SP1 5.38922
138 3RI1 3RH 5.44872
139 2V58 LZJ 5.44872
140 3FP0 FP0 5.44872
141 5X30 7XF 5.44872
142 5LNQ CAA 5.44872
143 5X30 4LM 5.44872
144 4XTX 590 5.55556
145 4HSJ 6PC 5.74713
146 2EQA AMP 5.76923
147 3NEM AMO 5.76923
148 3BL7 DD1 5.98007
149 2PZI AXX 6.31424
150 1OGZ EQU 6.4
151 3VPD ANP 6.40569
152 4UMX VVS 6.41026
153 5OO5 UUA 6.45161
154 4IPH 1FJ 6.50407
155 6F5U CQN 6.54762
156 3MTX PGT 6.62252
157 1BHX ASP PHE GLU GLU ILE 6.66667
158 3A06 NDP 6.73077
159 3E8N ATP 6.74487
160 3E8N VRA 6.74487
161 1UNB AKG 6.75241
162 1UNB PN1 6.75241
163 4UYE 9F9 6.77966
164 4TXE 38F 6.80272
165 5TBM 79A 6.83761
166 4WW8 VD9 6.84411
167 5YGE GLU 6.89655
168 1EOM NAG MAN MAN MAN NAG GAL NAG GAL 6.89655
169 6E08 NAP 7.05128
170 3DLS ADP 7.05128
171 2RHW C0E 7.06714
172 4CLI 5P8 7.37179
173 5B47 TPP 7.37179
174 1O2D NAP 7.37179
175 2P7Q GG6 7.5188
176 1Z4O GL1 7.69231
177 4WO4 JLS 7.7551
178 5FPX GLY SER SER HIS HIS HIS HIS HIS 7.9646
179 2PVN P63 8.01282
180 2PT9 2MH 8.33333
181 2PT9 S4M 8.33333
182 4B1L FRU 8.48485
183 4M1U A2G MBG 8.57143
184 3E2M E2M 8.64865
185 3LVW GSH 8.65385
186 4R3U 3KK 8.86076
187 4R3U 3HC 8.86076
188 5ULP KB1 8.95522
189 3PE2 E1B 8.97436
190 4IAW LIZ 9.04255
191 2I7C AAT 9.18728
192 5G3Y ADP 9.29204
193 3BZ3 YAM 9.42029
194 5IXG OTP 9.46746
195 2YNE NHW 9.61539
196 2YNE YNE 9.61539
197 2H6T IVA VAL VAL STA ALA STA 9.61539
198 4LFL TG6 9.88372
199 3GNE FLC 9.9359
200 4JH6 FCN 10.1449
201 4K3H 1OM 10.1695
202 5E2N V14 10.2662
203 5BU3 4W9 10.3261
204 2V2V V12 10.3321
205 5ZAI COA 10.4247
206 3VV1 GAL FUC 10.625
207 1OGX EQU 10.687
208 4WW7 AMP 10.728
209 5CG1 NAD BBN 11.1475
210 2Q4H AMP 11.2179
211 5UKL SIX 11.2903
212 3OVR 5SP 11.4035
213 2Z77 HE7 11.5108
214 5UR1 YY9 11.8971
215 4X8O AP5 12.1495
216 4ZU4 4TG 12.1622
217 4Z3X 4KX 12.8205
218 4Z3X MTE 12.8205
219 2BOS GLA GAL 13.2353
220 2BOS GLA GAL GLC 13.2353
221 2ART LPA AMP 13.3588
222 1TT8 PHB 13.4146
223 5WHU SIA GAL GLC 13.4228
224 5KD6 LBU 13.4615
225 3HXG GTA 14.2857
226 4MNS 2AX 14.4654
227 2V1O COA 17.2185
228 1EWJ BLM 18.254
229 1SU2 ATP 18.8679
230 2OBD 2OB 19.8718
231 2GJ5 VD3 22.8395
232 5OCG 9R5 23.8095
233 5Z84 PSC 23.913
234 5ZCO PSC 23.913
235 2DYR PSC 23.913
236 2DYS PSC 23.913
237 6FA4 D1W 26.5896
Pocket No.: 6; Query (leader) PDB : 1OFZ; Ligand: FUC; Similar sites found with APoc: 28
This union binding pocket(no: 6) in the query (biounit: 1ofz.bio1) has 13 residues
No: Leader PDB Ligand Sequence Similarity
1 3QH2 3NM 1.35747
2 4I94 ANP 1.66667
3 4CS4 AXZ 1.82482
4 4L3L 5FI 1.97368
5 7CPA FVF 2.28013
6 4MLO PAM 2.53623
7 1REQ DCA 2.5641
8 4X17 SIA SIA 2.57353
9 4ITU 1HS 2.60223
10 4RFR RHN 2.95567
11 4H6B 10X 3.07692
12 2XK9 XK9 3.20513
13 1OX5 1PR 3.20513
14 4EOX 0S5 3.44828
15 1Y7P RIP 4.03587
16 4O4K 2PK 4.80769
17 4O8A FAD 4.80769
18 2BJF DXC 4.80769
19 5ECP JAA 5.38117
20 3BGD PM6 5.38462
21 6G9I CXX 6.54762
22 5JJR SAH 7.05128
23 4OPC FDA 7.69231
24 3FRK TQP 7.69231
25 4RF2 NAP 8.45588
26 1US2 XYP XYP XYP XYP 9.29487
27 2Z77 NCA 11.5108
28 3SJH LAR 15.3846
Pocket No.: 7; Query (leader) PDB : 1OFZ; Ligand: FUL; Similar sites found with APoc: 37
This union binding pocket(no: 7) in the query (biounit: 1ofz.bio1) has 8 residues
No: Leader PDB Ligand Sequence Similarity
1 1ZEI CRS None
2 1NRL SRL 1.60256
3 5GUD 2IT 1.60256
4 1SQ5 PAU 1.62338
5 3RUU 37G 2.18341
6 2PX6 DH9 2.5641
7 4ITU NAI 2.60223
8 5JWC FAD 2.88462
9 5FII PHE 2.94118
10 4I42 1HA 3.15789
11 5N87 N66 3.20513
12 5H41 BGC GLC 3.20513
13 5CC2 CKA 3.39623
14 3IGO ANP 3.52564
15 5L7V GNL 3.84615
16 4XIZ LPP 4.11765
17 4XZ9 G3P 4.4843
18 4YSW FAD 4.80769
19 4YSW NAI 4.80769
20 5ZJ5 NAI 4.93827
21 3RI1 3RH 5.44872
22 2XZI KDM 5.44872
23 1VQ2 DDN 5.69948
24 3VRY B43 5.76923
25 3E8N ATP 6.74487
26 3E8N VRA 6.74487
27 2OMN IPH 6.91244
28 2DDQ HRB 7.33945
29 1WZ1 DNS 8.13008
30 2H5Z CTO 8.19672
31 5V1B 8UY 8.33333
32 2PS1 PRP 8.40708
33 3RUG DB6 9.31373
34 1IYK MYA 9.61539
35 4IP7 FLC 12.5
36 2DYS TGL 23.913
37 2DYR TGL 23.913
Pocket No.: 8; Query (leader) PDB : 1OFZ; Ligand: FUL; Similar sites found with APoc: 43
This union binding pocket(no: 8) in the query (biounit: 1ofz.bio1) has 12 residues
No: Leader PDB Ligand Sequence Similarity
1 3WHB DCC None
2 2IGA XX2 0.961538
3 5GZ9 ANP 1.31148
4 4ZAH T5K 1.60256
5 1Q19 SSC 1.92308
6 5Z6T NAP 2.24359
7 3BU5 ATP 2.28758
8 4FN4 NAD 2.3622
9 3RGA LSB 2.4735
10 4Z87 GDP 2.5641
11 5GP0 GPP 2.68456
12 1QIN GIP 2.73224
13 3PXP MYR 2.73973
14 3WXL ADP 2.88462
15 5VC5 96M 3.11419
16 4XAC AKG 3.1746
17 5XDT MB3 3.24675
18 5AX9 4KT 3.24675
19 2ZCQ B65 3.41297
20 3F3E LEU 3.52564
21 4H2D FMN 3.63636
22 2A8Y MTA 3.7037
23 5W7D MYR 3.84615
24 2PUL ACP 3.84615
25 1H74 ADP 4.05405
26 1F74 NAY 4.77816
27 3VDB 149 5.44872
28 1I1N SAH 5.75221
29 5DXT 5H5 5.76923
30 1S8G DAO 5.78512
31 1GT6 OLA 5.94796
32 4M52 FAD 6.08974
33 5K21 6QF 7.0922
34 2YIP YIO 7.24638
35 1VHD NAP 7.37179
36 4WN5 MVC 7.82609
37 3AFN NAP 8.91473
38 2GRU NAD 9.29487
39 3OBT SLB 11.859
40 5LRT ADP 12.5
41 5DWQ SFG 15
42 4NG2 OHN 16.8478
43 1N62 MCN 19.2771
Pocket No.: 9; Query (leader) PDB : 1OFZ; Ligand: FUL; Similar sites found with APoc: 3
This union binding pocket(no: 9) in the query (biounit: 1ofz.bio1) has 8 residues
No: Leader PDB Ligand Sequence Similarity
1 5QIN J2V 2.5641
2 6FNU FAD 2.92208
3 3HY3 10F 8.86699
Pocket No.: 10; Query (leader) PDB : 1OFZ; Ligand: FUC; Similar sites found with APoc: 45
This union binding pocket(no: 10) in the query (biounit: 1ofz.bio1) has 12 residues
No: Leader PDB Ligand Sequence Similarity
1 5DEY 59T 1.3468
2 2PA4 UPG 1.60256
3 5V2J UDP 2.24359
4 5V2J 7WV 2.24359
5 4P25 FUC GAL NAG FUC 2.31788
6 4Z87 5GP 2.5641
7 5GM5 CBI 2.72727
8 1BZY IMU 2.76498
9 5YJI SAH 2.8169
10 1VLJ NAP 2.88462
11 2ZYI STE 3.20513
12 4NST ADP 3.20513
13 4IX4 ADP 3.20513
14 1YNQ NDP 3.20513
15 5ABF XRJ 3.20513
16 1BYG STU 3.23741
17 3M0J OAF 3.25733
18 3MTW M3R 3.52564
19 3H7U NAP 3.52564
20 6CUZ FEV 3.52564
21 3PUR 2HG 3.52564
22 1H5R G1P 4.09556
23 4XB2 NDP 4.16667
24 4XB2 HSE 4.16667
25 5T79 NDP 4.16667
26 1HYH NAD 4.20712
27 3ZS7 ATP 4.33333
28 4UXH T5A 4.34783
29 4CYD CMP 5.77778
30 5K52 OCD 6.03774
31 5JE0 AZ8 6.47773
32 5JE0 SAH 6.47773
33 3KC1 2T6 6.82493
34 3JUK UPG 7.11744
35 5D85 P1T 7.37179
36 5D85 FLC 7.37179
37 3VC3 C6P 7.55814
38 1WD4 AHR 8.33333
39 1SMR PIV HIS PRO PHE HIS LPL TYR TYR SER 8.65385
40 4BMO FMN 10.5769
41 5EYP GDP 11.8343
42 4B1X LAB 15.3846
43 5ZZB LAB 15.3846
44 5ZZA LAB 15.3846
45 2V92 ATP 18.4713
Pocket No.: 11; Query (leader) PDB : 1OFZ; Ligand: FUL; Similar sites found with APoc: 13
This union binding pocket(no: 11) in the query (biounit: 1ofz.bio1) has 8 residues
No: Leader PDB Ligand Sequence Similarity
1 4NE2 SH2 1.60256
2 4NE2 ADP 1.60256
3 5FTW SAH 2.73438
4 5H41 IFM 3.20513
5 2MAS PIR 3.20513
6 5EEH SAH 3.52564
7 5FBN 5WF 4.05904
8 1H8S AIC 4.16667
9 1E4E PHY 4.48718
10 4YZC STU 5.12821
11 3AY6 BGC 9.29368
12 2X2M X2M 11.465
13 5EYP LOC 11.8343
Pocket No.: 12; Query (leader) PDB : 1OFZ; Ligand: FUL; Similar sites found with APoc: 132
This union binding pocket(no: 12) in the query (biounit: 1ofz.bio1) has 11 residues
No: Leader PDB Ligand Sequence Similarity
1 6BU0 IHP None
2 3KMZ EQO 0.75188
3 3W8X FTK 1.28205
4 3W8X FAD 1.28205
5 5A6N U7E 1.41343
6 5J5R IMP 1.60256
7 5J5R 6G1 1.60256
8 1XJD STU 1.60256
9 2PI8 NAG NAG NAG NAG NAG NAG 1.60256
10 3SLS ANP 1.64474
11 4I94 ANP 1.66667
12 1TPY SAH 1.74216
13 4JGP PYR 1.84332
14 5XCZ GLC BGC 1.92308
15 1OPB RET 2.23881
16 1EWF PC1 2.24359
17 6BJB 1VU 2.24359
18 1HZP DAO 2.24359
19 4L9I 8PR 2.24359
20 3GAY P6T 2.24359
21 2RG0 CTT 2.24359
22 3RGA ILD 2.4735
23 2GQS ADP 2.53165
24 1REQ DCA 2.5641
25 3EWC MCF 2.5641
26 4QWT ACD 2.5641
27 5Y72 DST 2.5641
28 1NE6 SP1 2.82686
29 1KHZ ADV 2.87081
30 3LXK MI1 2.88462
31 4MDH NAD 2.88462
32 3IES M24 2.88462
33 1G51 AMO 2.88462
34 5DNK SAH 2.88462
35 5W19 9TD 2.88462
36 4EWH T77 2.90909
37 3FSM 2NC 2.95567
38 4M8X KGQ 3.0303
39 1PZO CBT 3.04183
40 3TAY MN0 3.06748
41 4OJ8 AKG 3.07167
42 1KPG SAH 3.13589
43 1E1O LYS 3.20513
44 4B0T ADP 3.20513
45 2DHC DCE 3.22581
46 3OF1 CMP 3.25203
47 5ZW7 FAD 3.52564
48 1Z2P I3S 3.52564
49 1Z2P ACP 3.52564
50 5TDF ADP 3.52564
51 2C6Q IMP 3.52564
52 2XIQ MLC 3.52564
53 3OV6 MK0 3.52645
54 4YHO 4CC 3.65297
55 5GM9 CBK 3.75587
56 2Q7D ANP 3.84615
57 1TOI HCI 3.84615
58 1OKE BOG 3.84615
59 5EH0 5NW 3.87597
60 4GJ3 0XP 3.97351
61 2C49 ADN 3.97351
62 5ML3 DL3 4.02685
63 3PGU OLA 4.16667
64 2HGS ADP 4.16667
65 1A8P FAD 4.26357
66 3M3E GAL A2G NPO 4.34783
67 5X1M THG 4.48718
68 5A89 ADP 4.48718
69 5A89 FMN 4.48718
70 5X1M DHB 4.48718
71 3UXL CFI 4.48718
72 5WO4 B7V 4.63576
73 1ZP9 ATP 4.65116
74 1GQ2 NAP 4.80769
75 5N0L ILE 5.03145
76 2C31 TZD 5.12821
77 2C31 ADP 5.12821
78 6FL8 TIY 5.12821
79 6FL8 ADP 5.12821
80 3UDZ ADP 5.12821
81 6BXI ANP 5.12821
82 3O0G 3O0 5.13699
83 5NKB 8ZT 5.22876
84 3NRZ FAD 5.4878
85 4CQM NAP 5.7377
86 5FEU NAP 5.84192
87 4E1Z 0MX 5.84192
88 2P3C 3TL 6.06061
89 2FXD DR7 6.06061
90 2O4N TPV 6.06061
91 3NWQ 2NC 6.06061
92 5LXT ACP 6.08974
93 4LS7 1X9 6.08974
94 5DEP UD1 6.20155
95 3VPD ANP 6.40569
96 4NZN 2OU 6.41026
97 4NZN ANP 6.41026
98 5W4W 9WG 6.41026
99 5EVY SAL 6.41026
100 3PDT ADP 6.54545
101 2BWA GLC BGC 6.60793
102 5FFF NAP 6.61479
103 3IAE D7K 6.73077
104 2UZ1 TPP 6.73077
105 5AHM IMP 6.73077
106 5TBM 79A 6.83761
107 1JGU HBC 7.27273
108 4CLI 5P8 7.37179
109 4EUU BX7 7.69231
110 3PNA CMP 7.79221
111 4FE2 AIR 7.84314
112 4OAG ADP 8.01282
113 6ECG PM9 8.01282
114 2PVN P63 8.01282
115 3HZT J60 8.01282
116 5MZY 8EZ 8.06452
117 3HB5 E2B 8.8685
118 3PE2 E1B 8.97436
119 3LXN MI1 8.97436
120 1RM4 NDP 8.97436
121 3D9F N6C 9.29487
122 5C03 AGS 9.29487
123 2NVA PL2 9.9359
124 5KJZ PCG 10
125 4K3H 1OM 10.1695
126 4WW7 AMP 10.728
127 2Z77 HE7 11.5108
128 6CI9 NAP 11.583
129 1M5W DXP 11.9342
130 1DZK PRZ 12.7389
131 3VQ2 LP4 LP5 MYR DAO 13.7821
132 5DX0 SFG 15
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