-->
Receptor
PDB id Resolution Class Description Source Keywords
1OHE 2.2 Å EC: 3.-.-.- STRUCTURE OF CDC14B PHOSPHATASE WITH A PEPTIDE LIGAND HOMO SAPIENS PROTEIN PHOSPHATASE CELL CYCLE HYDROLASE
Ref.: THE STRUCTURE OF THE CELL CYCLE PROTEIN CDC14 REVEALS A PROLINE-DIRECTED PROTEIN PHOSPHATASE EMBO J. V. 22 3524 2003
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ACE ALA SEP PRO B:0;
Valid;
none;
submit data
392.281 n/a P(=O)...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1OHE 2.2 Å EC: 3.-.-.- STRUCTURE OF CDC14B PHOSPHATASE WITH A PEPTIDE LIGAND HOMO SAPIENS PROTEIN PHOSPHATASE CELL CYCLE HYDROLASE
Ref.: THE STRUCTURE OF THE CELL CYCLE PROTEIN CDC14 REVEALS A PROLINE-DIRECTED PROTEIN PHOSPHATASE EMBO J. V. 22 3524 2003
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 253 families.
1 1OHE - ACE ALA SEP PRO n/a n/a
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 209 families.
1 1OHE - ACE ALA SEP PRO n/a n/a
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 173 families.
1 1OHE - ACE ALA SEP PRO n/a n/a
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ACE ALA SEP PRO; Similar ligands found: 7
No: Ligand ECFP6 Tc MDL keys Tc
1 ACE ALA SEP PRO 1 1
2 ARG ALA ILE SEP LEU PRO 0.528736 0.919355
3 SER TYR SER PRO THR SEP PRO SER 0.438776 0.846154
4 ACE MET GLN SER SEP PRO LEU NH2 0.412281 0.8
5 TYR SEP PRO THR SEP PRO SER 0.409091 0.811594
6 ARG VAL ALA SEP PRO THR SER GLY VAL 0.408 0.814286
7 ACE GLU VAL ASN PRO 0.404255 0.734375
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1OHE; Ligand: ACE ALA SEP PRO; Similar sites found with APoc: 114
This union binding pocket(no: 1) in the query (biounit: 1ohe.bio1) has 14 residues
No: Leader PDB Ligand Sequence Similarity
1 4IJP 1EH 1.43678
2 5JFL NAD 1.43678
3 4L3L 5FI 1.64474
4 4A2A ATP 1.72414
5 1DIG L37 1.96078
6 1S16 ANP 2.01149
7 4CQE CQE 2.15827
8 4QYS PLP SEP 2.29885
9 1ON3 DXX 2.29885
10 2AG5 NAD 2.43902
11 2PA4 UPG 2.47678
12 5LU5 M7P 2.53807
13 5YVT NAI 2.65487
14 154L NAG NAG NAG 2.7027
15 1ZSQ PIB 2.87356
16 4C3Y FAD 2.87356
17 2WZF BGC 2.87356
18 5OOH 9ZZ 2.91262
19 5OOH NAP 2.91262
20 5Z2F NAP 3.01887
21 1RM4 NDP 3.2641
22 5O3Q CMP 3.33333
23 3FPZ AHZ 3.37423
24 3KAP FMN 3.40136
25 4HCX NDP 3.44828
26 3PNL ADP 3.44828
27 4D86 ADP 3.44828
28 4O1M NAD 3.49206
29 5X20 NAD 3.52564
30 4PLG NAI 3.59281
31 4PLG OXM 3.59281
32 5Y6Q FAD 3.7037
33 2VAP GDP 3.84615
34 3K7S R52 3.91061
35 4RKK GLC GLC GLC GLC GLC GLC 3.91566
36 2CNE DFJ 3.94737
37 2H21 SAM 4.02299
38 1JT2 FER 4.10448
39 4J7U NAP 4.16667
40 4J7U YTZ 4.16667
41 1XKD NAP 4.31034
42 5ESO TDP 4.31034
43 5ESO ISC 4.31034
44 4B9Q ATP 4.31034
45 5A89 FMN 4.48718
46 5A89 ADP 4.48718
47 3WG6 NDP 4.56026
48 1HKU NAD 4.5977
49 2RG0 CTT 4.5977
50 3ELW SAM 4.66667
51 3ELW GP3 4.66667
52 5THQ NDP 4.77941
53 4RSL FAD 4.88506
54 4J1Q NDP 4.88506
55 1EP2 ORO 4.98084
56 1EP2 FMN 4.98084
57 2BES RES 5.23256
58 4IJR NDP 5.23256
59 2VWT PYR 5.61798
60 2QHD DAO 5.7377
61 2F5Z FAD 5.74713
62 2X7J TPP 5.74713
63 4LRZ ADP 5.97484
64 3P9Y N7P THR SEP PRO SER TYR SET 6.06061
65 3RUV ANP 6.32184
66 1KNR FAD 6.32184
67 5OF9 ANP 6.32184
68 1PZG A3D 6.34441
69 2H04 4UN 6.38978
70 5Z21 NAI 6.42458
71 5EES NAP 6.47773
72 4CQM NAP 6.51341
73 1W5F G2P 6.6092
74 5KQG 6VX 6.74157
75 6CUZ FEV 6.89655
76 1AE1 NAP 6.95971
77 4IPE ANP 7.18391
78 4IVG ANP 7.18391
79 3ZEI AWH 7.18391
80 1L3I SAH 7.29167
81 3WCZ NAP 7.46753
82 3TA2 AKG 7.62712
83 6AM8 PLT 8.04598
84 6AMI TRP 8.04598
85 3AD8 NAD 8.08081
86 1C3V NDP 8.16327
87 5OVX AY5 8.19672
88 3O2Q PRO THR SEP PRO SER TYR 8.33333
89 5XDT MB3 8.44156
90 4RHY 3QG 8.45771
91 1NNU TCT 9.17031
92 1NNU NAD 9.17031
93 1D1Q 4NP 9.31677
94 3LN9 FLC 9.35252
95 4GE6 B26 9.55414
96 3HDY FAD 9.77011
97 1H0H 2MD 9.81308
98 6BYF CIT 10
99 1PA9 CSN 10.2113
100 3H8V ATP 10.274
101 1GY8 NAD 10.3448
102 4J51 N75 10.4294
103 4LFL TG6 10.4651
104 1U26 IHS 11.276
105 4KYQ FLC 12.5
106 2R40 EPH 12.5475
107 2V2V V12 12.9151
108 3O5X JZG 14.1304
109 3F81 STT 14.2077
110 4P4M D3T 15.5172
111 5FUI APY 15.9091
112 3RGQ 5P5 33.3333
113 4WOH 4NP 40.9639
114 2IMG MLT 43.7086
APoc FAQ
Feedback