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Receptor
PDB id Resolution Class Description Source Keywords
1PFK 2.4 Å EC: 2.7.1.11 CRYSTAL STRUCTURE OF THE COMPLEX OF PHOSPHOFRUCTOKINASE FROM ESCHERICHIA COLI WITH ITS REACTION PRODUCTS ESCHERICHIA COLI TRANSFERASE(PHOSPHOTRANSFERASE)
Ref.: CRYSTAL STRUCTURE OF THE COMPLEX OF PHOSPHOFRUCTOKI ESCHERICHIA COLI WITH ITS REACTION PRODUCTS. J.MOL.BIOL. V. 204 973 1988
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ADP A:324;
A:326;
B:324;
B:326;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
submit data
427.201 C10 H15 N5 O10 P2 c1nc(...
FBP A:323;
B:323;
Valid;
Valid;
none;
none;
submit data
340.116 C6 H14 O12 P2 C([C@...
MG A:325;
A:327;
B:325;
B:327;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
none;
none;
none;
none;
submit data
24.305 Mg [Mg+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1PFK 2.4 Å EC: 2.7.1.11 CRYSTAL STRUCTURE OF THE COMPLEX OF PHOSPHOFRUCTOKINASE FROM ESCHERICHIA COLI WITH ITS REACTION PRODUCTS ESCHERICHIA COLI TRANSFERASE(PHOSPHOTRANSFERASE)
Ref.: CRYSTAL STRUCTURE OF THE COMPLEX OF PHOSPHOFRUCTOKI ESCHERICHIA COLI WITH ITS REACTION PRODUCTS. J.MOL.BIOL. V. 204 973 1988
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 1PFK - FBP C6 H14 O12 P2 C([C@@H]1[....
70% Homology Family (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 4I7E Kd = 0.45 uM PEP C3 H5 O6 P C=C(C(=O)O....
2 4I4I Kd = 2.1 uM PEP C3 H5 O6 P C=C(C(=O)O....
3 4PFK - F6P C6 H13 O9 P C([C@@H]1[....
4 1PFK - FBP C6 H14 O12 P2 C([C@@H]1[....
50% Homology Family (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 4I7E Kd = 0.45 uM PEP C3 H5 O6 P C=C(C(=O)O....
2 4I4I Kd = 2.1 uM PEP C3 H5 O6 P C=C(C(=O)O....
3 4PFK - F6P C6 H13 O9 P C([C@@H]1[....
4 1PFK - FBP C6 H14 O12 P2 C([C@@H]1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ADP; Similar ligands found: 452
No: Ligand ECFP6 Tc MDL keys Tc
1 ADP 1 1
2 HEJ 0.9 1
3 ATP 0.9 1
4 A2D 0.895522 0.971831
5 5FA 0.887324 1
6 AQP 0.887324 1
7 AP5 0.884058 0.971831
8 B4P 0.884058 0.971831
9 BA3 0.869565 0.971831
10 AN2 0.84507 0.985915
11 AT4 0.84507 0.958904
12 M33 0.833333 0.958333
13 ACQ 0.826667 0.972222
14 A 0.823529 0.971429
15 AMP 0.823529 0.971429
16 ACP 0.821918 0.972222
17 6YZ 0.818182 0.972222
18 APR 0.810811 0.971831
19 AR6 0.810811 0.971831
20 ANP 0.802632 0.972222
21 SAP 0.8 0.945946
22 AGS 0.8 0.945946
23 AD9 0.8 0.972222
24 ADX 0.783784 0.873418
25 CA0 0.783784 0.945205
26 TAT 0.779221 0.958904
27 T99 0.779221 0.958904
28 50T 0.773333 0.958333
29 ABM 0.763889 0.917808
30 APC 0.763158 0.958904
31 PRX 0.763158 0.893333
32 ATF 0.759494 0.958904
33 A22 0.753086 0.985915
34 AP2 0.743243 0.958904
35 A12 0.743243 0.958904
36 SRA 0.736111 0.918919
37 ADQ 0.73494 0.945205
38 25L 0.732558 0.985915
39 5AL 0.725 0.931507
40 2A5 0.717949 0.918919
41 A1R 0.714286 0.907895
42 AU1 0.714286 0.972222
43 A3R 0.714286 0.907895
44 ATR 0.708861 0.971429
45 ADP PO3 0.708861 0.943662
46 PAP 0.708861 0.985714
47 SRP 0.707317 0.906667
48 7D3 0.706667 0.905405
49 25A 0.702381 0.971831
50 9X8 0.697674 0.92
51 OAD 0.697674 0.945205
52 RBY 0.6875 0.932432
53 ADV 0.6875 0.932432
54 00A 0.686047 0.883117
55 OOB 0.682353 0.931507
56 5SV 0.682353 0.848101
57 8QN 0.682353 0.931507
58 3OD 0.681818 0.945205
59 BIS 0.681818 0.933333
60 ALF ADP 0.674699 0.87013
61 ADP ALF 0.674699 0.87013
62 AMO 0.674419 0.932432
63 4AD 0.674419 0.92
64 PAJ 0.674419 0.884615
65 GAP 0.670732 0.893333
66 MAP 0.670588 0.945946
67 AHX 0.666667 0.896104
68 VO4 ADP 0.666667 0.931507
69 DLL 0.666667 0.931507
70 ADP VO4 0.666667 0.931507
71 PTJ 0.662921 0.896104
72 3UK 0.659091 0.918919
73 SON 0.658228 0.932432
74 LMS 0.653333 0.82716
75 LAD 0.651685 0.860759
76 WAQ 0.651685 0.883117
77 B5V 0.651685 0.906667
78 PR8 0.651685 0.85
79 ITT 0.65 0.943662
80 7D4 0.65 0.905405
81 G5P 0.648936 0.921053
82 XYA 0.647059 0.84507
83 ADN 0.647059 0.84507
84 RAB 0.647059 0.84507
85 1ZZ 0.644444 0.839506
86 ME8 0.644444 0.839506
87 FYA 0.644444 0.905405
88 NB8 0.644444 0.896104
89 TXA 0.644444 0.932432
90 6AD 0.642857 0.909091
91 ADP BMA 0.640449 0.918919
92 G3A 0.638298 0.921053
93 DAL AMP 0.632184 0.905405
94 AFH 0.631579 0.884615
95 9SN 0.630435 0.871795
96 9ZA 0.625 0.907895
97 DQV 0.625 0.958333
98 9ZD 0.625 0.907895
99 GTA 0.625 0.886076
100 YAP 0.623656 0.894737
101 B5M 0.623656 0.894737
102 FA5 0.623656 0.906667
103 B5Y 0.623656 0.894737
104 UP5 0.622449 0.92
105 HFD 0.619048 0.945946
106 XAH 0.617021 0.839506
107 AV2 0.616279 0.917808
108 AOC 0.615385 0.821918
109 48N 0.612245 0.896104
110 4UV 0.610526 0.894737
111 6V0 0.606061 0.896104
112 NAI 0.606061 0.907895
113 DND 0.606061 0.932432
114 NAX 0.606061 0.873418
115 NXX 0.606061 0.932432
116 TXD 0.606061 0.907895
117 5N5 0.605634 0.819444
118 5AS 0.604938 0.77907
119 A4P 0.60396 0.843373
120 DAT 0.60241 0.905405
121 A2R 0.602273 0.985915
122 TXE 0.6 0.907895
123 OMR 0.6 0.851852
124 4UU 0.597938 0.894737
125 GA7 0.597938 0.906667
126 A A 0.597826 0.944444
127 A4D 0.597222 0.819444
128 5CD 0.597222 0.805556
129 AP0 0.594059 0.896104
130 4TC 0.594059 0.896104
131 A3P 0.592593 0.971429
132 T5A 0.592233 0.841463
133 139 0.592233 0.873418
134 7D5 0.592105 0.878378
135 ATP A A A 0.589474 0.930556
136 LAQ 0.585859 0.839506
137 MYR AMP 0.585106 0.817073
138 F2R 0.580952 0.864198
139 YLP 0.58 0.819277
140 UPA 0.578431 0.907895
141 7DD 0.578313 0.985714
142 3AM 0.576923 0.929577
143 ADJ 0.576923 0.851852
144 COD 0.575472 0.811765
145 NAD 0.575472 0.931507
146 3AT 0.574713 0.971831
147 JB6 0.574468 0.883117
148 4UW 0.574257 0.860759
149 EP4 0.573333 0.753247
150 A2P 0.573171 0.957143
151 CNA 0.571429 0.932432
152 TYM 0.568627 0.906667
153 PPS 0.568182 0.873418
154 DTA 0.565789 0.786667
155 M2T 0.565789 0.734177
156 AR6 AR6 0.565657 0.917808
157 A3D 0.564815 0.918919
158 80F 0.564815 0.841463
159 3DH 0.564103 0.773333
160 G5A 0.563218 0.77907
161 YLB 0.563107 0.819277
162 YLC 0.563107 0.839506
163 AMP DBH 0.561224 0.893333
164 TYR AMP 0.561224 0.87013
165 MTA 0.558442 0.773333
166 DTP 0.556818 0.905405
167 AHZ 0.554455 0.817073
168 NA7 0.553191 0.958904
169 IOT 0.552381 0.831325
170 ZAS 0.55 0.766234
171 7MD 0.55 0.8625
172 ARG AMP 0.55 0.829268
173 IMO 0.548781 0.929577
174 YLA 0.54717 0.819277
175 NAE 0.544643 0.894737
176 TAD 0.544554 0.884615
177 A5A 0.544444 0.807229
178 2AM 0.544304 0.943662
179 TSB 0.543478 0.819277
180 6RE 0.54321 0.759494
181 AYB 0.542056 0.809524
182 NAQ 0.539823 0.871795
183 V3L 0.539326 0.971831
184 SSA 0.538462 0.8
185 AF3 ADP 3PG 0.538462 0.8375
186 ZID 0.535088 0.918919
187 LPA AMP 0.533981 0.817073
188 52H 0.532609 0.77907
189 VMS 0.532609 0.788235
190 54H 0.532609 0.788235
191 BTX 0.53211 0.841463
192 A3N 0.53012 0.786667
193 J7C 0.53012 0.769231
194 5X8 0.528736 0.763158
195 BT5 0.527273 0.831325
196 8X1 0.526882 0.752809
197 5CA 0.526882 0.8
198 53H 0.526882 0.77907
199 ARU 0.526316 0.860759
200 EAD 0.525862 0.873418
201 RGT 0.525253 0.958904
202 OVE 0.52439 0.905405
203 S4M 0.52381 0.666667
204 7DT 0.522727 0.985714
205 GDP 0.522222 0.92
206 DDS 0.522222 0.878378
207 AVV 0.521277 0.896104
208 NDE 0.521008 0.932432
209 7MC 0.518868 0.841463
210 DSH 0.518072 0.725
211 MAO 0.517647 0.759036
212 NSS 0.515789 0.8
213 DSZ 0.515789 0.8
214 LSS 0.515789 0.761364
215 P5A 0.515464 0.744444
216 DZD 0.513514 0.884615
217 NVA LMS 0.510417 0.752809
218 9K8 0.510204 0.714286
219 12D 0.509615 0.785714
220 M24 0.508772 0.85
221 YLY 0.508772 0.809524
222 P1H 0.508333 0.851852
223 5AD 0.506849 0.746479
224 GJV 0.505882 0.75
225 LEU LMS 0.505155 0.752809
226 AMP NAD 0.504505 0.905405
227 4TA 0.504505 0.807229
228 G A A A 0.504505 0.871795
229 NAJ PZO 0.504425 0.848101
230 GSU 0.5 0.77907
231 128 0.5 0.776471
232 KAA 0.5 0.752809
233 71V 0.5 0.907895
234 A3G 0.5 0.8
235 NDC 0.5 0.871795
236 7D7 0.5 0.743243
237 N0B 0.495726 0.819277
238 NJP 0.495495 0.945946
239 ODP 0.495495 0.909091
240 2SA 0.494624 0.932432
241 6C6 0.494505 0.881579
242 SFG 0.494382 0.75
243 0WD 0.491071 0.921053
244 YSA 0.490196 0.77907
245 PO4 PO4 A A A A PO4 0.489796 0.902778
246 SAM 0.48913 0.690476
247 6IA 0.48913 0.8375
248 A7D 0.488636 0.776316
249 6FA 0.488 0.841463
250 FB0 0.487805 0.804598
251 NAJ PYZ 0.487179 0.807229
252 A5D 0.483516 0.786667
253 IDP 0.483516 0.918919
254 SA8 0.483516 0.707317
255 PGS 0.483146 0.883117
256 MHZ 0.483146 0.697674
257 DA 0.482353 0.878378
258 D5M 0.482353 0.878378
259 NEC 0.482353 0.746667
260 NIA 0.481928 0.822785
261 Y3J 0.480519 0.726027
262 8PZ 0.480392 0.8
263 FAD 0.480315 0.851852
264 FAS 0.480315 0.851852
265 FDA 0.48 0.833333
266 N6P 0.479592 0.915493
267 GGZ 0.479167 0.825
268 U A 0.478261 0.907895
269 SAH 0.478261 0.74359
270 SAI 0.478261 0.734177
271 A G 0.477876 0.883117
272 NPW 0.477477 0.886076
273 NDP 0.477477 0.921053
274 AAM 0.476744 0.971429
275 C2R 0.47561 0.90411
276 AMZ 0.47561 0.916667
277 A A A 0.474747 0.905405
278 GTP 0.473684 0.92
279 U A G G 0.473684 0.883117
280 SMM 0.473684 0.686047
281 NZQ 0.473214 0.909091
282 TXP 0.473214 0.921053
283 A3S 0.47191 0.810811
284 SFD 0.46875 0.734043
285 AIR 0.468354 0.901408
286 AAT 0.468085 0.707317
287 EEM 0.468085 0.690476
288 J7V 0.466667 0.833333
289 Z5A 0.466667 0.77907
290 7C5 0.466667 0.818182
291 62F 0.465649 0.8625
292 HDV 0.463158 0.893333
293 FAY 0.462121 0.8625
294 A3T 0.461538 0.821918
295 ETB 0.461538 0.833333
296 DCA 0.461538 0.823529
297 A6D 0.46 0.722892
298 A U 0.459459 0.87013
299 GEK 0.459184 0.7375
300 6K6 0.459184 0.930556
301 RFL 0.458647 0.821429
302 NAP 0.458333 0.945205
303 S7M 0.458333 0.690476
304 4YB 0.457944 0.761364
305 WSA 0.454545 0.788235
306 TAP 0.454545 0.907895
307 FNK 0.454545 0.804598
308 COA 0.453782 0.823529
309 0T1 0.453782 0.823529
310 101 0.453488 0.878378
311 XNP 0.452174 0.873418
312 NA0 0.45082 0.932432
313 7RP 0.448276 0.928571
314 GP3 0.446809 0.921053
315 TM1 0.446602 0.77381
316 APU 0.446429 0.894737
317 PUA 0.445378 0.884615
318 V1N 0.443396 0.917808
319 7RA 0.443182 0.957747
320 COS 0.442623 0.804598
321 AMX 0.442623 0.833333
322 30N 0.442623 0.752688
323 CAO 0.442623 0.795455
324 QQY 0.44186 0.815789
325 ACK 0.44186 0.861111
326 649 0.441441 0.744444
327 0UM 0.44 0.698795
328 NHD 0.439655 0.905405
329 CMX 0.439024 0.823529
330 SCO 0.439024 0.823529
331 GCP 0.438776 0.896104
332 8BR 0.438202 0.906667
333 GNH 0.4375 0.907895
334 8Q2 0.4375 0.772727
335 3AD 0.4375 0.805556
336 NVA 2AD 0.43617 0.759494
337 62X 0.435644 0.666667
338 FCX 0.435484 0.795455
339 ACO 0.435484 0.795455
340 FAM 0.435484 0.804598
341 9JJ 0.434783 0.8625
342 GNP 0.434343 0.896104
343 9GM 0.434343 0.896104
344 NMX 0.433071 0.76087
345 MGP 0.43299 0.884615
346 26A 0.432099 0.763158
347 HAX 0.432 0.804598
348 K15 0.431373 0.682353
349 DG1 0.430894 0.921053
350 1DG 0.430894 0.921053
351 QQX 0.430233 0.805195
352 2VA 0.430108 0.8
353 S8M 0.43 0.759494
354 2MC 0.429688 0.769231
355 6G0 0.428571 0.884615
356 P5F 0.428571 0.823529
357 FYN 0.428571 0.823529
358 3KK 0.428571 0.804598
359 A C A C 0.428571 0.848101
360 7L1 0.427419 0.795455
361 FAI 0.426966 0.916667
362 RMB 0.426966 0.873239
363 AS 0.426966 0.833333
364 1RB 0.425287 0.885714
365 CA6 0.425197 0.729167
366 SOP 0.425197 0.804598
367 OXK 0.425197 0.804598
368 MCD 0.425197 0.804598
369 COK 0.425197 0.804598
370 G1R 0.424242 0.907895
371 SXZ 0.423077 0.710843
372 CC5 0.423077 0.816901
373 F2N 0.422535 0.813953
374 EO7 0.422222 0.788235
375 ANZ 0.422018 0.8
376 1VU 0.421875 0.795455
377 CMC 0.421875 0.804598
378 CO6 0.421875 0.804598
379 ZDA 0.421053 0.864865
380 GKE 0.420561 0.884615
381 GDC 0.420561 0.884615
382 GDD 0.420561 0.884615
383 NFD 0.420168 0.883117
384 GSP 0.42 0.873418
385 D3Y 0.42 0.789474
386 MC4 0.419847 0.76087
387 3D1 0.419753 0.773333
388 3L1 0.419753 0.773333
389 FA9 0.41958 0.864198
390 5GP 0.419355 0.906667
391 G 0.419355 0.906667
392 KB1 0.419048 0.698795
393 CAJ 0.418605 0.804598
394 SCD 0.418605 0.823529
395 CMP 0.417582 0.901408
396 2BA 0.417582 0.915493
397 SO8 0.416667 0.789474
398 VRT 0.416667 0.769231
399 N01 0.416667 0.905405
400 IVC 0.415385 0.813953
401 1HE 0.415385 0.786517
402 A1S 0.415385 0.804598
403 BCO 0.415385 0.804598
404 3HC 0.415385 0.813953
405 MLC 0.415385 0.804598
406 NMN AMP PO4 0.415254 0.87013
407 2FA 0.414634 0.813333
408 MGO 0.414141 0.860759
409 3NZ 0.413462 0.782051
410 COO 0.412214 0.804598
411 MCA 0.412214 0.795455
412 YE1 0.412214 0.813953
413 CAA 0.412214 0.813953
414 GAV 0.411765 0.884615
415 PRT 0.411215 0.931507
416 JLN 0.411111 0.890411
417 P2P 0.411111 0.902778
418 ZZB 0.410256 0.77381
419 SP1 0.409091 0.842105
420 RP1 0.409091 0.842105
421 2CP 0.409091 0.795455
422 SCA 0.409091 0.804598
423 103 0.409091 0.837838
424 PAX 0.408 0.829268
425 FAD NBT 0.407143 0.75
426 COW 0.406015 0.795455
427 3CP 0.406015 0.804598
428 IRC 0.406015 0.813953
429 BYC 0.406015 0.804598
430 CA8 0.406015 0.729167
431 1GZ 0.406015 0.795455
432 COF 0.406015 0.786517
433 HGG 0.406015 0.804598
434 2KQ 0.406015 0.786517
435 G2P 0.405941 0.884615
436 SLU 0.404959 0.770115
437 U A C C 0.404959 0.858974
438 RBZ 0.404494 0.849315
439 1CZ 0.404412 0.795455
440 FAQ 0.402985 0.804598
441 BCA 0.402985 0.795455
442 4CA 0.402985 0.795455
443 MTP 0.402439 0.730769
444 8OD 0.402062 0.945205
445 CO7 0.401515 0.804598
446 GRA 0.4 0.804598
447 G2R 0.4 0.884615
448 ENQ 0.4 0.916667
449 CNV FAD 0.4 0.8
450 GMV 0.4 0.896104
451 HXC 0.4 0.786517
452 HF7 0.4 0.893333
Ligand no: 2; Ligand: FBP; Similar ligands found: 9
No: Ligand ECFP6 Tc MDL keys Tc
1 AFP 1 1
2 FBP 1 1
3 F1X 0.744186 0.954545
4 TA6 0.666667 0.954545
5 F6P 0.666667 0.954545
6 FDP 0.462963 0.954545
7 OI7 0.448276 0.976744
8 F1P 0.418182 0.847826
9 AHG 0.404255 0.930233
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1PFK; Ligand: FBP; Similar sites found with APoc: 2
This union binding pocket(no: 1) in the query (biounit: 1pfk.bio1) has 15 residues
No: Leader PDB Ligand Sequence Similarity
1 4OEV OXL 2.1875
2 3WN0 FUB 2.8125
Pocket No.: 2; Query (leader) PDB : 1PFK; Ligand: FBP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 1pfk.bio1) has 15 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 3; Query (leader) PDB : 1PFK; Ligand: FBP; Similar sites found with APoc: 8
This union binding pocket(no: 3) in the query (biounit: 1pfk.bio1) has 16 residues
No: Leader PDB Ligand Sequence Similarity
1 2P0D I3P None
2 2QB8 ATP 2.8125
3 4N2R FUB 2.8125
4 5X7Q GLC GLC GLC GLC 4.0625
5 4R6W SAH 5.03876
6 2J5V RGP 5.9375
7 3FS1 ALA ALA LEU ALA ALA LEU LEU ALA ALA 6.08696
8 3K1X DBX 8.46154
Pocket No.: 4; Query (leader) PDB : 1PFK; Ligand: FBP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 1pfk.bio1) has 16 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 5; Query (leader) PDB : 1PFK; Ligand: ADP; Similar sites found with APoc: 297
This union binding pocket(no: 5) in the query (biounit: 1pfk.bio1) has 17 residues
No: Leader PDB Ligand Sequence Similarity
1 5MT9 SRO None
2 5MT9 ARG None
3 4ZGM 32M None
4 2VOH CIT None
5 4ZAL FNR None
6 4ZAL 4LR None
7 3RG9 WRA 1.25
8 3RG9 NDP 1.25
9 1D4D FAD 1.25
10 4UP3 NDP 1.27389
11 4UP3 FAD 1.27389
12 4XB4 45D 1.31579
13 3G5D 1N1 1.74825
14 3WR7 COA 1.76471
15 4NTC FAD 1.875
16 4MO4 ACP 1.875
17 3WQT ANP 1.875
18 1VPE ANP 2.1875
19 1QPG MAP 2.1875
20 2I3G NAP 2.1875
21 5I39 FAD 2.1875
22 3QCJ NX4 2.25806
23 5XDT MB3 2.27273
24 5XDT GDP 2.27273
25 1RYI GOA 2.35602
26 1RYI FAD 2.35602
27 4G86 BNT 2.46479
28 3IA4 NDP 2.46914
29 4KVL PLM 2.5
30 2QV7 ADP 2.5
31 1E4I NFG 2.5
32 3K6V CIT 2.5
33 1EWF PC1 2.5
34 6HH6 A3R 2.5
35 3KDU NKS 2.52708
36 4L50 D8X 2.63158
37 5AZC PGT 2.66667
38 4V3I ASP LEU THR ARG PRO 2.72374
39 3H8V ATP 2.73973
40 2VZZ SCA 2.75229
41 5ZYN FAD 2.8125
42 6AMI TRP 2.8125
43 4D5G FAD 2.8125
44 4D5G TPP 2.8125
45 3ZLB ANP 2.8125
46 1OZH HE3 2.8125
47 3NRR D16 2.8125
48 3NRR NAP 2.8125
49 4O48 ASP 2.8125
50 1C0I FAD 2.8125
51 1C0I BE2 2.8125
52 4HA6 FAD 2.8125
53 4XW2 SIM 3.0303
54 3HQ9 OXL 3.125
55 1GET NAP 3.125
56 1BZL GCG 3.125
57 1E8G FAD 3.125
58 1E8G FCR 3.125
59 2RAB FAD 3.125
60 6A3J NAI 3.125
61 5L13 6ZE 3.125
62 1TKB N1T 3.125
63 2UZ1 TPP 3.125
64 4TV1 36M 3.18725
65 5A96 GTP 3.21285
66 3VET TOY 3.4375
67 2CUN 3PG 3.4375
68 3VET CP 3.4375
69 3VET ADP 3.4375
70 2HQM FAD 3.4375
71 4C3Y ANB 3.4375
72 1RM0 NAI 3.4375
73 3WGT FAD 3.4375
74 4C3Y FAD 3.4375
75 4RKX 3S9 3.44828
76 2VVT I24 3.44828
77 4R3L COA 3.46821
78 2B6N ALA PRO THR 3.59712
79 2YIP YIO 3.62319
80 1DR1 NAP 3.7037
81 1DR1 HBI 3.7037
82 4WBD CIT 3.75
83 4CZG QH3 3.75
84 4CZG ADP 3.75
85 1ZPD DPX 3.75
86 5EXW 7DT 3.75
87 6EOF ADP 3.75
88 6ASY ATP 3.75
89 6CB2 OLC 3.75427
90 2BL9 NDP 3.78151
91 1FL2 FAD 3.87097
92 2GN3 MAN 3.96825
93 6BR8 6OU 3.96825
94 1TV5 N8E 4.0625
95 2R75 01G 4.0625
96 5EOU ATP 4.0625
97 2VBF TPP 4.0625
98 1QO8 FAD 4.0625
99 5HSA FAS 4.0625
100 1RPN NDP 4.0625
101 6AM8 PLT 4.0625
102 5HTX ADP 4.0625
103 5Z99 SLB 4.0625
104 1TDF NAP 4.11392
105 5NM7 GLY 4.13534
106 6A46 DCM 4.29688
107 4KOT CE3 4.32099
108 3ZJ0 ACO 4.36893
109 6BMS POV 4.375
110 3QVP FAD 4.375
111 3KJS NAP 4.375
112 3LAD FAD 4.375
113 6H3O FAD 4.375
114 5NTP 98E 4.62185
115 1ZX5 LFR 4.66667
116 1T9D P22 4.6875
117 2F5Z FAD 4.6875
118 1V59 FAD 4.6875
119 5WKC AUJ 4.6875
120 5EXE 5SR 4.6875
121 5WKC TP9 4.6875
122 4X9M FAD 4.6875
123 4YNU FAD 4.6875
124 4YNU LGC 4.6875
125 2R5N RP5 4.6875
126 4EI7 GDP 4.6875
127 2R5N TPP 4.6875
128 3MG9 GHP 3MY 3FG GHP GHP OMY 3FG 4.7619
129 1COY FAD 5
130 2NVK FAD 5
131 2YCH ATP 5
132 3IHG FAD 5
133 6G3R ADP 5
134 2BUP ADP 5
135 2BUP ATP 5
136 1WWZ ACO 5.03145
137 1AOE NDP 5.20833
138 1AOE GW3 5.20833
139 1FWV SGA MAG FUC 5.22388
140 1YXM ADE 5.28053
141 3GDN FAD 5.3125
142 3GDN HBX 5.3125
143 5K0A FAD 5.3125
144 4EFH ADP 5.3125
145 4AT0 FAD 5.3125
146 3Q9T FAY 5.3125
147 4LAE NAP 5.38922
148 4LAE 1VM 5.38922
149 1N1D C2G 5.42636
150 1YAG ATP 5.625
151 4B1X ATP 5.625
152 1PJS NAD 5.625
153 4B1V ATP 5.625
154 4B1V LAB 5.625
155 2FF3 ATP 5.625
156 2V51 ATP 5.625
157 2FXU ATP 5.625
158 5YEE ATP 5.625
159 4H03 LAR 5.625
160 4H03 ATP 5.625
161 1KXP ATP 5.625
162 2FF6 ATP 5.625
163 4PKG ATP 5.625
164 4PKI ATP 5.625
165 3MN9 ATP 5.625
166 4B1W ATP 5.625
167 5YPU ATP 5.625
168 4CBU ATP 5.625
169 3KIF GDL 5.66038
170 5FJN FAD 5.70175
171 3U4L ATP 5.71429
172 2P4Y C03 5.77617
173 5DHU 5A8 5.88235
174 5ZZB ATP 5.88235
175 1U72 NDP 5.91398
176 1U72 MTX 5.91398
177 5LXT GDP 5.9375
178 2IHU TP9 5.9375
179 2IHT TPP 5.9375
180 1UPA TPP 5.9375
181 3RYC GTP 5.9375
182 4ZNO SUC 5.9375
183 3CTY FAD 5.95611
184 1S7N COA 6.04396
185 1QF9 C5P 6.18557
186 1QF9 ADP 6.18557
187 1QF9 ALF 6.18557
188 3QMN A3P 6.20155
189 1ZED PNP 6.25
190 4GNI ATP 6.25
191 4WGF HX2 6.34146
192 1SUW NAP 6.4257
193 3KV8 FAH 6.47482
194 5ZI9 FLC 6.53846
195 5DUS APR 6.54762
196 5CB3 APR 6.55738
197 4DP3 MMV 6.5625
198 4DP3 NDP 6.5625
199 1YBH P22 6.5625
200 5AJU RP5 6.56934
201 2NU8 COA 6.59722
202 1YRE COA 6.59898
203 5ZZA ATP 6.61157
204 3DFR NDP 6.79012
205 1BOB ACO 6.875
206 4JD3 COA 6.875
207 4JD3 PLM 6.875
208 2V7Y ADP 6.875
209 3R96 AMP 6.91489
210 3R96 ACO 6.91489
211 2Q97 ATP 6.97674
212 5B47 PYR 7.1875
213 5B47 TPP 7.1875
214 4OR7 NAP 7.27273
215 2A3Z ATP 7.30769
216 2A40 ATP 7.30769
217 2A42 ATP 7.30769
218 1YKI FMN 7.37327
219 1YKI NFZ 7.37327
220 5ZBK AMP 7.38916
221 4EIL NDP 7.5
222 4OKS 2T9 7.5
223 3ABI NAD 7.5
224 4AVB ACO 7.5
225 6G1P CIT 7.8125
226 4J56 FAD 7.89474
227 2D0O ADP 8
228 1NVM NAD 8.125
229 2VK4 TPP 8.125
230 5LX9 OLB 8.14332
231 2FZH DH1 8.25243
232 4KBS PX2 8.37209
233 4QC6 30N 8.37989
234 1TL2 NDG 8.47458
235 5LWY OLB 8.56164
236 4ZLU ADP 8.75
237 4ZLU 4PW 8.75
238 3ITJ FAD 8.75
239 3ITJ CIT 8.75
240 1JUV NDP 8.80829
241 2NXW TPP 9.0625
242 3MN7 ATP 9.18367
243 2C42 PYR 9.375
244 2C42 TPP 9.375
245 5B3A 0JO 9.375
246 3QKD HI0 9.6875
247 4M7V RAR 9.71429
248 2VWA PTY 9.90099
249 2WOR 2AN 10
250 1J3I NDP 10
251 1J3I WRA 10
252 6CS8 F9Y 10.231
253 4RJK TPP 10.3125
254 6F97 FAD 10.9375
255 4PL8 ATP 10.9589
256 5Y02 HBX 11.215
257 6GAS FAD 11.25
258 3K56 IS3 11.2782
259 1V0C KNC 11.3861
260 1V0C ACO 11.3861
261 2GUD BMA 11.4754
262 2HYR BGC GLC 11.4754
263 2GUD MAN 11.4754
264 2GUC MAN 11.4754
265 2NU5 NAG 11.4754
266 2HYQ MAN MAN 11.4754
267 2GUE NAG 11.4754
268 2NUO BGC 11.4754
269 2F6U CIT 11.5385
270 5B48 TDN 11.5625
271 4OGQ 7PH 11.875
272 3MN5 ATP 11.875
273 3CIP ATP 12.5
274 5MIT FAD 13.1498
275 5MIT NAP 13.1498
276 4KM2 ATR 13.4078
277 4KM2 TOP 13.4078
278 2GAG FAD 13.4375
279 1IUP ALQ 13.8298
280 3SJH ATP 14.8148
281 3SJH LAR 14.8148
282 5ZBL AMP 15.2709
283 3EEL 53T 15.4185
284 6GL8 F3Q 16.2791
285 3K5I AIR 17.1875
286 4RHE FMN 17.2249
287 2D1K ATP 18.75
288 2CNT COA 19.375
289 3ZLR X0B 19.6203
290 3B1J NAD 20
291 2PBD ATP 20.9302
292 1APZ ASP 21.2766
293 3KIH GDL 21.6495
294 3F8D FAD 23.75
295 5DXV NAP 24.359
296 5M37 9SZ 25
297 2PAV ATP 25
Pocket No.: 6; Query (leader) PDB : 1PFK; Ligand: ADP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 6) in the query (biounit: 1pfk.bio1) has 17 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 7; Query (leader) PDB : 1PFK; Ligand: ADP; Similar sites found with APoc: 16
This union binding pocket(no: 7) in the query (biounit: 1pfk.bio1) has 19 residues
No: Leader PDB Ligand Sequence Similarity
1 3KP6 SAL None
2 3MDV CL6 2.5
3 4LHD GLY 3.125
4 1L5Y BEF 3.22581
5 4Y30 SAH 3.75
6 4Y30 49L 3.75
7 2VL1 GLY GLY 4.0625
8 1XPJ TLA 5.55556
9 5IM3 DTP 6.5625
10 1GXU 2HP 6.59341
11 5WS9 OXL 6.875
12 3AYI FAD 6.875
13 3AYI HCI 6.875
14 2BHW XAT 8.18966
15 3RUV ANP 10.9375
16 5W3Y IHP 13.4375
Pocket No.: 8; Query (leader) PDB : 1PFK; Ligand: ADP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 8) in the query (biounit: 1pfk.bio1) has 19 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 9; Query (leader) PDB : 1PFK; Ligand: ADP; Similar sites found with APoc: 14
This union binding pocket(no: 9) in the query (biounit: 1pfk.bio1) has 18 residues
No: Leader PDB Ligand Sequence Similarity
1 5HH0 COA 4
2 4N14 WR7 4.77707
3 2E5V FAD 5.3125
4 5B4B LP5 6.04839
5 3E3U NVC 6.59898
6 5OCA 9QZ 6.875
7 6A5Y 9R0 7.01754
8 4OIV XX9 7.07965
9 4LIK CIT 7.8125
10 1R6T TYM 8.125
11 3K1X DBX 8.46154
12 3OKI OKI 8.58369
13 4PGK Y69 9.42623
14 6C0B MLI 9.6875
Pocket No.: 10; Query (leader) PDB : 1PFK; Ligand: ADP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 10) in the query (biounit: 1pfk.bio1) has 18 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 11; Query (leader) PDB : 1PFK; Ligand: ADP; Similar sites found with APoc: 52
This union binding pocket(no: 11) in the query (biounit: 1pfk.bio1) has 18 residues
No: Leader PDB Ligand Sequence Similarity
1 1MVN FMN 1.91388
2 2G86 UMP 2.21519
3 5LJ0 6XX 2.30769
4 5V4R MGT 2.46914
5 2IYA UDP 2.5
6 3EYA TDP 2.55009
7 5ESO ISC 2.8125
8 5ESO TDP 2.8125
9 4EHU ANP 2.89855
10 1YQZ FAD 3.4375
11 3WGT QSC 3.4375
12 4ORM 2V6 4.0625
13 4ORM FMN 4.0625
14 4ORM ORO 4.0625
15 6CUZ FEV 4.375
16 5EXK 5AD 4.375
17 3E85 BSU 4.43038
18 1T9D FAD 4.6875
19 1T9D PYD 4.6875
20 1T9D 1MM 4.6875
21 1T9D P25 4.6875
22 3NYC FAD 4.6875
23 3NYC IAR 4.6875
24 5OSW DIU 4.6875
25 1H9A NAP 4.6875
26 4YDU ADP 5.06329
27 3L9R L9Q 5.10204
28 3A5Z KAA 5.625
29 5FJN BE2 5.70175
30 5N8V KZZ 5.7971
31 4PLT NAI 5.9375
32 3QMN COA 6.20155
33 1FTH A3P 6.55738
34 4BGB ADP 6.5625
35 3M89 GSP 6.5625
36 2EVL GAL SPH EIC 6.69856
37 3N7S 3N7 6.95652
38 6BVJ EAS 7.78443
39 6BVL EBY 7.78443
40 3O01 DXC 7.79221
41 6GQM F8H 7.8125
42 3R35 4CO 7.94702
43 2GZM DGL 8.98876
44 4R57 ACO 9.09091
45 2BTO GTP 9.25926
46 2NV2 GLN 9.80392
47 5EYP GTP 10.0592
48 4RJK TDL 10.3125
49 1GTE FAD 11.25
50 6GMN F4E 13.4021
51 2IYF UDP 13.75
52 1HE1 AF3 15.9091
Pocket No.: 12; Query (leader) PDB : 1PFK; Ligand: ADP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 12) in the query (biounit: 1pfk.bio1) has 18 residues
No: Leader PDB Ligand Sequence Similarity
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