Receptor
PDB id Resolution Class Description Source Keywords
1PJ6 1.65 Å EC: 1.5.3.10 CRYSTAL STRUCTURE OF DIMETHYLGLYCINE OXIDASE OF ARTHROBACTER GLOBIFORMIS IN COMPLEX WITH FOLIC ACID ARTHROBACTER GLOBIFORMIS CHANNELLING FOLATE BINDING FAD BINDING AMINE OXIDATION OXIDOREDUCTASE
Ref.: CHANNELLING AND FORMATION OF 'ACTIVE' FORMALDEHYDE DIMETHYLGLYCINE OXIDASE. EMBO J. V. 22 4038 2003
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
FAD A:902;
Invalid;
none;
submit data
785.55 C27 H33 N9 O15 P2 Cc1cc...
FOL A:2887;
Valid;
none;
submit data
441.397 C19 H19 N7 O6 c1cc(...
NA A:2001;
Part of Protein;
none;
submit data
22.99 Na [Na+]
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1PJ6 1.65 Å EC: 1.5.3.10 CRYSTAL STRUCTURE OF DIMETHYLGLYCINE OXIDASE OF ARTHROBACTER GLOBIFORMIS IN COMPLEX WITH FOLIC ACID ARTHROBACTER GLOBIFORMIS CHANNELLING FOLATE BINDING FAD BINDING AMINE OXIDATION OXIDOREDUCTASE
Ref.: CHANNELLING AND FORMATION OF 'ACTIVE' FORMALDEHYDE DIMETHYLGLYCINE OXIDASE. EMBO J. V. 22 4038 2003
Members (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 3GSI - THG C19 H23 N7 O6 c1cc(ccc1C....
2 1PJ6 - FOL C19 H19 N7 O6 c1cc(ccc1C....
3 1PJ7 - FFO C20 H23 N7 O7 c1cc(ccc1C....
70% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 3GSI - THG C19 H23 N7 O6 c1cc(ccc1C....
2 1PJ6 - FOL C19 H19 N7 O6 c1cc(ccc1C....
3 1PJ7 - FFO C20 H23 N7 O7 c1cc(ccc1C....
50% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 3GSI - THG C19 H23 N7 O6 c1cc(ccc1C....
2 1PJ6 - FOL C19 H19 N7 O6 c1cc(ccc1C....
3 1PJ7 - FFO C20 H23 N7 O7 c1cc(ccc1C....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: FOL; Similar ligands found: 19
No: Ligand ECFP6 Tc MDL keys Tc
1 FOL 1 1
2 29D 0.617647 0.967742
3 29C 0.617647 0.967742
4 28Z 0.617647 0.967742
5 DZF 0.58 0.983333
6 04J 0.545455 0.885246
7 DHF 0.514563 0.863636
8 9L9 0.45 0.791045
9 3TZ 0.447368 0.863636
10 FON 0.447368 0.802817
11 THF 0.446429 0.780822
12 83A 0.445455 0.921875
13 TLL 0.436975 0.75
14 LYA 0.429907 0.875
15 FFO 0.429825 0.802817
16 THG 0.428571 0.863636
17 1YJ 0.428571 0.863636
18 C2F 0.421053 0.77027
19 MTX 0.410714 0.779412
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1PJ6; Ligand: FOL; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 1pj6.bio2) has 22 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 2; Query (leader) PDB : 1PJ6; Ligand: FOL; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 1pj6.bio1) has 22 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 3; Query (leader) PDB : 1PJ6; Ligand: FOL; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 3) in the query (biounit: 1pj6.bio1) has 22 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 4; Query (leader) PDB : 1PJ6; Ligand: FOL; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 1pj6.bio1) has 22 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 5; Query (leader) PDB : 1PJ6; Ligand: FOL; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 5) in the query (biounit: 1pj6.bio1) has 22 residues
No: Leader PDB Ligand Sequence Similarity
APoc FAQ
Feedback