-->
Receptor
PDB id Resolution Class Description Source Keywords
1PL6 2 Å EC: 1.1.1.14 HUMAN SDH/NADH/INHIBITOR COMPLEX HOMO SAPIENS SORBITOL DEHYDROGENASE CP-166572 OXIDOREDUCTASE
Ref.: X-RAY CRYSTALLOGRAPHIC AND KINETIC STUDIES OF HUMAN DEHYDROGENASE. STRUCTURE V. 11 1071 2003
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
572 A:405;
B:407;
C:409;
D:411;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
Ki = 154 nM
301.365 C11 H19 N5 O3 S CN(C)...
NAD A:404;
B:406;
C:408;
D:410;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
submit data
663.425 C21 H27 N7 O14 P2 c1cc(...
ZN A:402;
B:402;
C:402;
D:402;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
none;
none;
none;
none;
submit data
65.409 Zn [Zn+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1PL6 2 Å EC: 1.1.1.14 HUMAN SDH/NADH/INHIBITOR COMPLEX HOMO SAPIENS SORBITOL DEHYDROGENASE CP-166572 OXIDOREDUCTASE
Ref.: X-RAY CRYSTALLOGRAPHIC AND KINETIC STUDIES OF HUMAN DEHYDROGENASE. STRUCTURE V. 11 1071 2003
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 1PL6 Ki = 154 nM 572 C11 H19 N5 O3 S CN(C)S(=O)....
2 1PL8 - NAD C21 H27 N7 O14 P2 c1cc(c[n+]....
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 1PL6 Ki = 154 nM 572 C11 H19 N5 O3 S CN(C)S(=O)....
2 1PL8 - NAD C21 H27 N7 O14 P2 c1cc(c[n+]....
50% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 1PL6 Ki = 154 nM 572 C11 H19 N5 O3 S CN(C)S(=O)....
2 1PL8 - NAD C21 H27 N7 O14 P2 c1cc(c[n+]....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: 572; Similar ligands found: 1
No: Ligand ECFP6 Tc MDL keys Tc
1 572 1 1
Ligand no: 2; Ligand: NAD; Similar ligands found: 230
No: Ligand ECFP6 Tc MDL keys Tc
1 A3D 0.872727 0.986111
2 NHD 0.821429 0.972222
3 NAP 0.811966 0.986111
4 NFD 0.791304 0.946667
5 NXX 0.765766 0.972603
6 DND 0.765766 0.972603
7 AMP NAD 0.74359 0.972222
8 ZID 0.737705 0.986111
9 NAQ 0.729508 0.934211
10 NAE 0.721311 0.959459
11 NA0 0.712 0.972603
12 TAP 0.704 0.921053
13 NDE 0.689922 0.972603
14 NAJ 0.683333 0.972222
15 NDC 0.679389 0.934211
16 NDO 0.674603 0.958904
17 N01 0.656 0.972222
18 CNA 0.642276 0.972603
19 NBP 0.621212 0.922078
20 8ID 0.609756 0.922078
21 A2D 0.576923 0.958333
22 ADP 0.575472 0.931507
23 NGD 0.574803 0.922078
24 BA3 0.566038 0.958333
25 M33 0.564815 0.918919
26 ADP PO3 0.563636 0.957747
27 B4P 0.560748 0.958333
28 AP5 0.560748 0.958333
29 AN2 0.555556 0.918919
30 AT4 0.555556 0.894737
31 GAP 0.553571 0.932432
32 OOB 0.551724 0.972222
33 CA0 0.550459 0.932432
34 9JJ 0.546053 0.898734
35 HEJ 0.545455 0.931507
36 ACP 0.545455 0.906667
37 ATP 0.545455 0.931507
38 DQV 0.544 0.972222
39 ADP ALF 0.54386 0.883117
40 ALF ADP 0.54386 0.883117
41 DAL AMP 0.543103 0.945205
42 APR 0.540541 0.931507
43 AQP 0.540541 0.931507
44 AR6 0.540541 0.931507
45 5FA 0.540541 0.931507
46 ADP VO4 0.53913 0.945205
47 VO4 ADP 0.53913 0.945205
48 AD9 0.535714 0.906667
49 SAP 0.535714 0.883117
50 AGS 0.535714 0.883117
51 WAQ 0.533333 0.896104
52 ABM 0.53271 0.905405
53 DLL 0.529412 0.972222
54 00A 0.529412 0.921053
55 ACQ 0.526316 0.906667
56 NJP 0.526316 0.959459
57 ANP 0.526316 0.906667
58 OAD 0.525 0.932432
59 ADX 0.522523 0.839506
60 5AL 0.521739 0.945205
61 A1R 0.521008 0.871795
62 9SN 0.520325 0.909091
63 A 0.518868 0.930556
64 AMP 0.518868 0.930556
65 50T 0.517857 0.893333
66 ATF 0.517241 0.894737
67 1ZZ 0.516393 0.851852
68 3OD 0.516393 0.932432
69 SON 0.513514 0.92
70 PRX 0.513274 0.881579
71 6YZ 0.512821 0.906667
72 SRP 0.512821 0.92
73 9X8 0.512397 0.883117
74 ADP BMA 0.512397 0.932432
75 3UK 0.512397 0.958904
76 MYR AMP 0.512195 0.851852
77 NAJ PZO 0.510949 0.909091
78 NMN 0.509434 0.875
79 A3R 0.508333 0.871795
80 B5V 0.508197 0.945946
81 AMP DBH 0.507937 0.906667
82 A22 0.504202 0.945205
83 ATP A A A 0.504 0.971831
84 B5M 0.504 0.933333
85 FA5 0.504 0.945946
86 8QN 0.5 0.945205
87 NAX 0.496183 0.886076
88 TYR AMP 0.496063 0.933333
89 PR8 0.495935 0.8625
90 AMO 0.495868 0.92
91 ADQ 0.495868 0.932432
92 4AD 0.495868 0.933333
93 PAJ 0.495868 0.873418
94 A12 0.495495 0.894737
95 AP2 0.495495 0.894737
96 AHZ 0.492308 0.851852
97 YAP 0.492063 0.933333
98 FYA 0.491935 0.918919
99 AHX 0.491803 0.884615
100 4UU 0.488372 0.933333
101 5SV 0.487603 0.8375
102 TAT 0.487179 0.894737
103 T99 0.487179 0.894737
104 APC 0.486957 0.894737
105 SRA 0.486239 0.881579
106 6V0 0.484848 0.909091
107 NAI 0.484848 0.921053
108 GTA 0.484615 0.898734
109 A A 0.483871 0.958333
110 LAD 0.483871 0.873418
111 AU1 0.482456 0.906667
112 F2R 0.481752 0.831325
113 OMR 0.481203 0.841463
114 TXE 0.481203 0.921053
115 AF3 ADP 3PG 0.481203 0.873418
116 LAQ 0.480916 0.851852
117 G3A 0.48062 0.909091
118 B5Y 0.480315 0.933333
119 NB8 0.48 0.884615
120 TXA 0.48 0.92
121 BIS 0.48 0.871795
122 ME8 0.48 0.851852
123 PTJ 0.48 0.884615
124 139 0.477941 0.886076
125 LPA AMP 0.477273 0.851852
126 AFH 0.476923 0.873418
127 AR6 AR6 0.476923 0.958333
128 G5P 0.476923 0.909091
129 ARG AMP 0.476923 0.841463
130 25L 0.47619 0.945205
131 NAJ PYZ 0.475524 0.864198
132 25A 0.47541 0.958333
133 9ZA 0.47541 0.896104
134 9ZD 0.47541 0.896104
135 DZD 0.47482 0.897436
136 TXD 0.473684 0.921053
137 4UV 0.472868 0.933333
138 TYM 0.470149 0.945946
139 RBY 0.470085 0.894737
140 ADV 0.470085 0.894737
141 4TA 0.467626 0.864198
142 48N 0.466165 0.884615
143 XAH 0.465116 0.851852
144 4UW 0.462687 0.897436
145 M24 0.461538 0.886076
146 80F 0.460993 0.853659
147 IOT 0.459854 0.821429
148 T5A 0.456522 0.853659
149 EAD 0.455782 0.886076
150 MAP 0.455285 0.883117
151 GA7 0.454545 0.894737
152 BT5 0.453901 0.821429
153 A4P 0.452555 0.833333
154 UP5 0.451852 0.933333
155 PAP 0.445378 0.917808
156 4TC 0.445255 0.909091
157 AP0 0.445255 0.884615
158 YLP 0.444444 0.831325
159 P1H 0.443709 0.864198
160 AOC 0.442478 0.810811
161 Z5A 0.439189 0.833333
162 LMS 0.4375 0.817073
163 2A5 0.436975 0.857143
164 A G 0.43662 0.921053
165 G A A A 0.43662 0.909091
166 COD 0.43662 0.802326
167 ADJ 0.435714 0.841463
168 YLB 0.434783 0.831325
169 YLC 0.434783 0.851852
170 U A G G 0.433566 0.921053
171 ATR 0.433333 0.90411
172 7MD 0.432836 0.851852
173 8X1 0.432 0.764045
174 G5A 0.429752 0.790698
175 PO4 PO4 A A A A PO4 0.429688 0.943662
176 TAD 0.42963 0.873418
177 5AS 0.42735 0.770115
178 BTX 0.426573 0.831325
179 YLA 0.425532 0.831325
180 DSZ 0.425197 0.790698
181 NCN 0.424779 0.805556
182 UPA 0.42446 0.921053
183 8PZ 0.424242 0.811765
184 VMS 0.424 0.8
185 54H 0.424 0.8
186 9K8 0.423077 0.744444
187 N0B 0.422819 0.853659
188 6AD 0.422764 0.85
189 AYB 0.422535 0.821429
190 7D3 0.422414 0.844156
191 YLY 0.421769 0.821429
192 TSB 0.420635 0.809524
193 ODP 0.41958 0.922078
194 AV2 0.419355 0.855263
195 FB0 0.419355 0.775281
196 A5A 0.419355 0.819277
197 NNR 0.419048 0.739726
198 A A A 0.418605 0.918919
199 U A 0.417808 0.946667
200 649 0.417266 0.775281
201 NMN AMP PO4 0.416667 0.933333
202 SSA 0.416 0.790698
203 P5A 0.415385 0.755556
204 LSS 0.414062 0.772727
205 A2R 0.412698 0.918919
206 52H 0.412698 0.790698
207 JB6 0.412214 0.896104
208 5N5 0.411215 0.783784
209 YSA 0.410448 0.811765
210 53H 0.409449 0.790698
211 5CA 0.409449 0.790698
212 ITT 0.408333 0.878378
213 7D4 0.408333 0.844156
214 NA7 0.407692 0.894737
215 LEU LMS 0.407692 0.784091
216 5CD 0.407407 0.794521
217 0WD 0.406897 0.909091
218 A3P 0.40678 0.930556
219 HFD 0.406504 0.883117
220 AVV 0.40625 0.860759
221 RAB 0.40566 0.808219
222 XYA 0.40566 0.808219
223 ADN 0.40566 0.808219
224 FDA 0.405063 0.823529
225 GSU 0.40458 0.790698
226 7MC 0.404255 0.831325
227 NSS 0.403101 0.811765
228 6FA 0.402516 0.853659
229 PPS 0.4 0.817073
230 NVA LMS 0.4 0.784091
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1PL6; Ligand: 572; Similar sites found with APoc: 936
This union binding pocket(no: 1) in the query (biounit: 1pl6.bio2) has 32 residues
No: Leader PDB Ligand Sequence Similarity
1 5N0J FAD 0.854701
2 1OC2 NAD 0.862069
3 1OC2 TDX 0.862069
4 6CEP OXM 0.898204
5 6CEP NAD 0.898204
6 5FEU NAP 1.03093
7 4OHU NAD 1.03806
8 4OHU 2TK 1.03806
9 5TOW NAI 1.1236
10 5TOW ADN 1.1236
11 5FFF NAP 1.16732
12 5FFF 5XC 1.16732
13 4ZCC NAI 1.19048
14 4ZCC FAD 1.19048
15 1V8B NAD 1.40449
16 1E5Q NDP 1.40449
17 1P31 EPU 1.40449
18 3L9W AMP 1.40449
19 1UP7 NAD 1.40449
20 4EDF UPG 1.40449
21 1TB4 PEJ 1.40449
22 2C5A GDC 1.40449
23 2C5A NAD 1.40449
24 3L9W GSH 1.40449
25 1P3D UMA 1.40449
26 1U1I NAD 1.40449
27 3H5N ATP 1.41643
28 1NYT NAP 1.47601
29 3ITJ CIT 1.47929
30 3ITJ FAD 1.47929
31 2HJR APR 1.52439
32 5K4W THR 1.55763
33 5K4W NAI 1.55763
34 1ZK4 NAP 1.59363
35 6C4M NAP 1.68539
36 5TS5 FAD 1.68539
37 3X0V FAD 1.68539
38 1ZK7 FAD 1.68539
39 3LU1 NAD 1.68539
40 5TTJ FAD 1.68539
41 5JWC FAD 1.68539
42 4YT4 FE9 1.68539
43 3FG2 FAD 1.68539
44 3GDN HBX 1.68539
45 4RPL 3UC 1.68539
46 4RPL FAD 1.68539
47 1YS4 NAP 1.69492
48 6GAR FAD 1.7192
49 5ZI2 NAD 1.73913
50 5ZI2 ADP 1.73913
51 4XB2 NDP 1.79104
52 4XB2 HSE 1.79104
53 3KB6 NAD 1.79641
54 2CVQ NDP 1.83486
55 6F9Q NAD 1.83824
56 5GZ6 7C3 1.84049
57 5GZ6 NDP 1.84049
58 3A4V PYR 1.89274
59 3A4V NAD 1.89274
60 1HYH NAD 1.94175
61 1UXG NAD 1.94175
62 1UXG FUM 1.94175
63 3VYW SAM 1.94805
64 4B5W PYR 1.95312
65 5XVH NAP 1.96078
66 2CDU ADP 1.96629
67 5U8U FAD 1.96629
68 3UOY NAP 1.96629
69 3UOY FAD 1.96629
70 3ETG GLU 1.96629
71 5VN0 NAI 1.96629
72 3SQP FAD 1.96629
73 5KVS NAP 1.96629
74 1XHC FAD 1.96629
75 4KVL PLM 1.96629
76 2Q1S NAI 1.96629
77 5DF1 58X 1.96629
78 5DF1 NAP 1.96629
79 2IVD FAD 1.96629
80 3ETG NDP 1.96629
81 2EG5 SAH 1.96629
82 2VVL FAD 1.96629
83 1Z45 NAD 1.96629
84 3ETG GTP 1.96629
85 1D4D FAD 1.96629
86 5VN0 FAD 1.96629
87 5OC1 FAD 1.96629
88 1PGP 6PG 1.96629
89 1VKO NAD 1.96629
90 5EZ7 FAD 1.96629
91 5KVS 6XR 1.96629
92 2V6G NAP 1.96629
93 2CDU FAD 1.96629
94 1H9A NAP 1.96629
95 3SSO SAH 1.96629
96 2WSB NAD 1.9685
97 1ORR NAD 2.01729
98 5Y8L HUI 2.0339
99 5Y8L NAD 2.0339
100 1Y1P NMN AMP PO4 2.04678
101 3H8V ATP 2.05479
102 1VL0 NAI 2.05479
103 3B1F NAD 2.06897
104 4XDY NAI 2.07101
105 3L4S NAD 2.08333
106 3L4S 3PG 2.08333
107 4LS3 HIS 2.1021
108 1PZG A3D 2.1148
109 2F1K NAP 2.15054
110 4O0L NDP 2.18182
111 1KYQ NAD 2.18978
112 5OFW 9TW 2.24215
113 5KKA 6V0 2.24359
114 4OPC PGT 2.24719
115 3ULK NDP 2.24719
116 2WPF FAD 2.24719
117 2WPF WPF 2.24719
118 4OPC FDA 2.24719
119 4KP7 NAP 2.24719
120 4U8P UDP 2.24719
121 4KP7 1UQ 2.24719
122 4U8P FDA 2.24719
123 5YB7 FAD 2.24719
124 2DKH FAD 2.24719
125 5YB7 ORN 2.24719
126 4XYB NDP 2.24719
127 1DJN ADP 2.24719
128 2DKH 3HB 2.24719
129 1YY5 FAD 2.24719
130 1RSG FAD 2.24719
131 3AB1 FAD 2.24719
132 5I39 FAD 2.24719
133 4REP FAD 2.24719
134 6F97 FAD 2.24719
135 1WVG APR 2.24719
136 2EFX NFA 2.24719
137 1EQ2 NAP 2.25806
138 2DTX BMA 2.27273
139 1E3W NAD 2.29885
140 1E6W NAD 2.30769
141 1FLJ GSH 2.30769
142 4JJF FE9 2.32558
143 5N6C NAD 2.33333
144 2C29 NAP 2.37389
145 2C29 DQH 2.37389
146 3ORF NAD 2.39044
147 3CMC NAD 2.39521
148 4Z0H NAD 2.39521
149 4ZVV GN0 2.40964
150 4ZVV NAD 2.40964
151 9LDT NAD 2.40964
152 9LDB NAD 2.40964
153 1O5I NAD 2.40964
154 5Y1G NAD 2.43902
155 5Y1G AKB 2.43902
156 5G4L NDP 2.44755
157 1EDO NAP 2.45902
158 1G0N NDP 2.4735
159 1G0N PHH 2.4735
160 4TQG NDP 2.47678
161 4D42 NAP 2.48227
162 4D42 W0I 2.48227
163 1E7S NAP 2.49221
164 4R5M NAP 2.52809
165 1RM0 D6P 2.52809
166 5NMX NAP 2.52809
167 2YVF FAD 2.52809
168 2YVF NAD 2.52809
169 1Q0H NDP 2.52809
170 1Q0H FOM 2.52809
171 2IID PHE 2.52809
172 2IID FAD 2.52809
173 4HXY NDP 2.52809
174 4MIG G3F 2.52809
175 5JCA NDP 2.52809
176 1RM0 NAI 2.52809
177 6FHO FAD 2.52809
178 3KLJ FAD 2.52809
179 5JCA FAD 2.52809
180 4UZI IMD 2.52809
181 4G5H NAP 2.52809
182 4G5H UD7 2.52809
183 4R5M 4NO 2.52809
184 2RGJ FAD 2.52809
185 3V1U NAD 2.52809
186 5NMX FAD 2.52809
187 3NKS FAD 2.52809
188 4DSG UDP 2.52809
189 4DSG FAD 2.52809
190 2VVM FAD 2.52809
191 3S5W FAD 2.52809
192 3S5W NAP 2.52809
193 4USQ FAD 2.52809
194 4XFR CIT 2.52809
195 1YQZ FAD 2.52809
196 3FWN ATR 2.52809
197 4UP3 NDP 2.54777
198 1JA9 NDP 2.55474
199 5X20 NAD 2.5641
200 5N53 8NB 2.5641
201 1AE1 NAP 2.5641
202 5AYV KPL 2.589
203 5NII FAD 2.589
204 5AYV NAP 2.589
205 5Z20 NAI 2.6087
206 2VZ0 NAP 2.61194
207 2VZ0 D64 2.61194
208 2WD7 NAP 2.61194
209 6DNT NAD 2.61628
210 4Y9D NAI 2.62295
211 2YYY NAP 2.62391
212 5NM7 GLY 2.63158
213 5A1T NAI 2.6393
214 5A1T OXM 2.6393
215 1O6Z NAD 2.64026
216 1YJQ NAP 2.64026
217 1ZH8 NAP 2.64706
218 4NTD FAD 2.64706
219 5JE8 NAD 2.64901
220 3V1Y NAD 2.67062
221 4R1S NAP 2.67062
222 3AXB PRO 2.67857
223 3AXB FAD 2.67857
224 5OJL TXP 2.68456
225 4Q9N NAI 2.68456
226 4NTC FAD 2.68657
227 1OAA OAA 2.7027
228 5K0A FAD 2.72727
229 2PZM UDP 2.72727
230 2PZM NAD 2.72727
231 1V35 NAI 2.73556
232 5OCM NAP 2.74914
233 3FPZ AHZ 2.76074
234 2CVZ NDP 2.76817
235 3F8D FAD 2.78638
236 2AQJ TRP 2.80899
237 2AQJ FAD 2.80899
238 1BZL FAD 2.80899
239 1BZL GCG 2.80899
240 5BVA FAD 2.80899
241 1PN0 FAD 2.80899
242 1PN0 IPH 2.80899
243 1N1G BCP 2.80899
244 5GSN NAP 2.80899
245 5GSN FAD 2.80899
246 5YAP NAI 2.80899
247 1GR0 NAD 2.80899
248 5GSN MMZ 2.80899
249 4AP3 FAD 2.80899
250 4AP3 NAP 2.80899
251 5YAP 8S0 2.80899
252 4IV9 FAD 2.80899
253 2NVK FAD 2.80899
254 3LXD FAD 2.80899
255 2NVK NAP 2.80899
256 3QFA FAD 2.80899
257 5NA1 FAD 2.80899
258 5E7G XYS BGC BGC XYS BGC XYS BGC BGC BGC 2.80899
259 1QMG APX 2.80899
260 5XNC MTA 2.80899
261 2EWM NAD 2.81124
262 2ZB3 NDP 2.83286
263 2I3G NAP 2.84091
264 1C3V NDP 2.85714
265 1XG5 NAP 2.86738
266 5TWB FAD 2.90698
267 5O4J SAH 2.91971
268 5O4J PJL 2.91971
269 5O4J 9KH 2.91971
270 1O5Q PYR 2.95082
271 3TW1 AHN 2.95359
272 3RFV 15L 2.99625
273 3RFV NAI 2.99625
274 2GDZ NAD 2.99625
275 1VI2 NAD 3
276 4KOA NDP 3.003
277 6BWL NAD 3.04878
278 1H5S TMP 3.07167
279 2O4C NAD 3.08989
280 6A3J SOE 3.08989
281 3OJO NAD 3.08989
282 3T31 DCQ 3.08989
283 3T31 FAD 3.08989
284 6A3J NAI 3.08989
285 3E1T FAD 3.08989
286 1I2B UPG 3.08989
287 1I2B USQ 3.08989
288 1I2B NAD 3.08989
289 1VJT NAD 3.08989
290 3AYI HCI 3.08989
291 3AYI FAD 3.08989
292 5JY6 NAD 3.08989
293 1P6O HPY 3.10559
294 1NPD NAD 3.125
295 5F7J ADE 3.125
296 2QZZ NAP 3.14465
297 2QZZ EMF 3.14465
298 4FN4 NAD 3.14961
299 3O9Z NAD 3.20513
300 3O9Z AKG 3.20513
301 2YY7 NAD 3.20513
302 5BSH PRO 3.2491
303 1UDB UFG 3.25444
304 1UDB NAD 3.25444
305 2VT3 ATP 3.25581
306 1RM4 NDP 3.2641
307 1R6D DAU 3.2641
308 1R6D NAD 3.2641
309 4PLG NAI 3.29341
310 4PLG OXM 3.29341
311 4MDH NAD 3.29341
312 1DRV A3D 3.2967
313 3BAZ NAP 3.3033
314 5MDH NAD 3.3033
315 1V6A TRE 3.31325
316 3HB5 NAP 3.36391
317 2IZ1 ATR 3.37079
318 1EBF NAD 3.37079
319 1KJ8 GAR 3.37079
320 5LD5 NAD 3.37079
321 6C4T NA7 3.37079
322 1GZ4 ATP 3.37079
323 2NU8 COA 3.37079
324 1K3T BRZ 3.37079
325 1Q9I FAD 3.37079
326 1Q9I TEO 3.37079
327 4YKG NAD 3.37079
328 3M89 GSP 3.37079
329 4YKG FAD 3.37079
330 2Z3Y F2N 3.37079
331 1VL8 NAP 3.37079
332 4BV6 FAD 3.37079
333 4ISS TAR 3.37079
334 4YNU LGC 3.37079
335 1WP4 NDP 3.46021
336 3JQA NAP 3.47222
337 5JDI NAP 3.47222
338 3JQB NAP 3.47222
339 3JQG NAP 3.47222
340 3JQ9 NAP 3.47222
341 4CM4 NAP 3.47222
342 4CM8 NAP 3.47222
343 3JQ7 NAP 3.47222
344 4CLO NAP 3.47222
345 5JDC NAP 3.47222
346 5JCJ NAP 3.47222
347 5K6A NAP 3.47222
348 3BMN NAP 3.47222
349 4CME NAP 3.47222
350 4CM9 NAP 3.47222
351 4CMI NAP 3.47222
352 3JQ8 NAP 3.47222
353 4CLR NAP 3.47222
354 3BMO NAP 3.47222
355 3BMQ NAP 3.47222
356 3JQF NAP 3.47222
357 3VZS NAP 3.50195
358 3VZS CAA 3.50195
359 1HYE NAP 3.51438
360 4K5S PM0 3.54478
361 4K5S FAD 3.54478
362 2Q46 NAP 3.55731
363 4L8V NAP 3.56083
364 1BDB NAD 3.61011
365 1J0X NAD 3.61446
366 4PLT NAI 3.62538
367 4PLT OXM 3.62538
368 5O42 NAD 3.64964
369 5O42 BGC 3.64964
370 5O42 9JW 3.64964
371 3WUC GLC GAL 3.64964
372 5NUF NAD 3.65169
373 1X14 NAD 3.65169
374 2QRK AMP 3.65169
375 1V59 NAD 3.65169
376 4EIP FAD 3.65169
377 1V59 FAD 3.65169
378 4D04 FAD 3.65169
379 4D04 NAP 3.65169
380 1FEC FAD 3.65169
381 5KOX FAD 3.65169
382 5KOX RFP 3.65169
383 5BUK FAD 3.65169
384 3WQQ NDP 3.65169
385 3WQQ IB3 3.65169
386 4MOP 2H5 3.65169
387 5MQ6 NDP 3.65169
388 4X9M FAD 3.65169
389 4B63 NAP 3.65169
390 4B63 ORN 3.65169
391 4B63 FAD 3.65169
392 2R4J FAD 3.65169
393 2R4J 13P 3.65169
394 2Q1W NAD 3.65169
395 6C4N NAP 3.65169
396 4EIP K2C 3.65169
397 3IHG FAD 3.65169
398 4EUE NAI 3.65169
399 2PV7 NAD 3.69128
400 1SB8 UD2 3.69318
401 1SB8 NAD 3.69318
402 1LC3 NAD 3.7415
403 3OIG NAD 3.7594
404 1U7T TDT 3.83142
405 1QG6 TCL 3.83142
406 1QG6 NAD 3.83142
407 1U7T NAD 3.83142
408 4ZRN UPG 3.84615
409 4ZRN NAD 3.84615
410 1FL2 FAD 3.87097
411 5N2I NAP 3.87931
412 4DPL NAP 3.89972
413 3QPB URA 3.90071
414 5Z21 NAI 3.91061
415 5NUE NAD 3.91566
416 6GAS FAD 3.92749
417 3ICS ADP 3.93258
418 5M67 3D1 3.93258
419 5M67 ADE 3.93258
420 5M67 NAD 3.93258
421 3ICT ADP 3.93258
422 6F3N ADN 3.93258
423 6F3N NAD 3.93258
424 6F3M NAD 3.93258
425 1GQ2 NAP 3.93258
426 1O0S NAI 3.93258
427 5KMS NAD 3.93258
428 2D2I NAP 3.93258
429 2IXB NAD 3.93258
430 1YKJ FAD 3.93258
431 1YKJ PHB 3.93258
432 2GV8 FAD 3.93258
433 1REO FAD 3.93258
434 2GV8 NDP 3.93258
435 1X87 NAD 3.93258
436 2IXB A2G 3.93258
437 2YG3 FAD 3.93258
438 2GVC FAD 3.93258
439 5UAO FAD 3.93258
440 1VQW FAD 3.93258
441 3WMX NAD 3.93258
442 3GF4 UPG 3.93258
443 3GF4 FAD 3.93258
444 1LVL NAD 3.93258
445 5WGR FAD 3.93258
446 4E5N NAD 3.93939
447 1LDM NAD 3.95137
448 4B4U NAP 3.9604
449 1SOW NAD 3.96341
450 1W6U NAP 3.97351
451 1X7D ORN 4
452 1X7D NAD 4
453 4NBU NAI 4
454 2RGH FAD 4.02802
455 5XWV 8H6 4.03226
456 5XWV NDP 4.03226
457 2PK3 A2R 4.04984
458 3B20 NAD 4.12979
459 1H5Q NAP 4.15094
460 5GT9 NAP 4.18251
461 5YEC ATP 4.20168
462 1J49 NAD 4.2042
463 3A06 FOM 4.21348
464 3CIF NAD 4.21348
465 2XVE FAD 4.21348
466 1SC6 NAD 4.21348
467 3A06 NDP 4.21348
468 3CIF G3H 4.21348
469 2JB2 FAD 4.21348
470 2JB2 PHE 4.21348
471 6FP4 E1T 4.21348
472 5TUK FAD 4.21348
473 4CP8 MLI 4.21348
474 6FP4 FAD 4.21348
475 2XVF FAD 4.21348
476 1GTE FAD 4.21348
477 3QVP FAD 4.21348
478 4GYS MLI 4.21348
479 1KNR FAD 4.21348
480 3LZW FAD 4.21687
481 3LZW NAP 4.21687
482 5EJ2 NAD 4.22078
483 1FK8 NAD 4.28016
484 3OZ2 FAD 4.28212
485 2Q7V FAD 4.30769
486 2CUL FAD 4.31034
487 4J1Q NDP 4.31034
488 5GWT SIN 4.31655
489 5GWT NAD 4.31655
490 3WGT QSC 4.32277
491 3WGT FAD 4.32277
492 2B4R NAD 4.34783
493 2B4R AES 4.34783
494 4YJK URA 4.36508
495 5OOH 9ZZ 4.36893
496 5OOH NAP 4.36893
497 2QA1 FAD 4.4
498 1EZ4 NAD 4.40252
499 3OA2 NAD 4.40252
500 1FWV SGA MAG FUC 4.47761
501 3OND NAD 4.49438
502 3OND ADN 4.49438
503 1QO8 FAD 4.49438
504 3CGB FAD 4.49438
505 5J7X FAD 4.49438
506 1CZA G6P 4.49438
507 2Q0L NAP 4.50161
508 2Q0L FAD 4.50161
509 1BXK NAD 4.50704
510 4RDH AMP 4.51389
511 4RDI ATP 4.51389
512 5Z2F NAP 4.5283
513 1CER NAD 4.53172
514 5G6U TRP 4.5977
515 4CQM NAP 4.5977
516 4CJX NAP 4.70219
517 4D79 ATP 4.71014
518 1JAY NAP 4.71698
519 5U5G NAP 4.74576
520 2B9W FAD 4.77528
521 4J36 1HR 4.77528
522 4J36 FAD 4.77528
523 3CGD FAD 4.77528
524 3CGD NAD 4.77528
525 3CGD COA 4.77528
526 4EMI NAD 4.77528
527 3UCL NAP 4.77528
528 6ER9 FAD 4.77528
529 6ER9 NAP 4.77528
530 4TXI FAD 4.77528
531 1W8D NAP 4.77528
532 3UCL CYH 4.77528
533 3UCL FAD 4.77528
534 5JCM NAD 4.77528
535 5JCM FAD 4.77528
536 5JCM ISD 4.77528
537 1W73 NAP 4.77528
538 4GUT FAD 4.77528
539 4HSU FAD 4.77528
540 2ZB4 NAP 4.77528
541 4GUS FAD 4.77528
542 4FWE FAD 4.77528
543 2ZB4 5OP 4.77528
544 2BRY FAD 4.77528
545 4EMI FAD 4.77528
546 2NAD NAD 4.77528
547 5HSA FAS 4.77528
548 3HDY FAD 4.77528
549 3HDY FDA 4.77528
550 3HDY GDU 4.77528
551 4XZ3 COA 4.78261
552 4XYM COA 4.78261
553 3PPQ CHT 4.82315
554 3AY6 BGC 4.83271
555 3AY6 NAI 4.83271
556 5D4V SAH 4.85075
557 3EGI ADP 4.85437
558 5EES NAP 4.8583
559 1ZBQ NAD 4.89297
560 5Z2L NDP 4.89796
561 3ZNN 4WL 4.89914
562 3ZNN FAD 4.89914
563 1ZQ9 SAM 4.91228
564 4DDY DN6 4.94297
565 1GZ6 NAI 5.01567
566 4JK3 NAD 5.01931
567 4J4H NAI 5.01931
568 4J4H 1J1 5.01931
569 2HNK SAH 5.02092
570 3K5I AIR 5.05618
571 5GUD 2IT 5.05618
572 5GUD NDP 5.05618
573 1GET NAP 5.05618
574 1GET FAD 5.05618
575 4CNK FAD 5.05618
576 5GUD CIT 5.05618
577 2GMH FAD 5.05618
578 1KEW NAD 5.05618
579 5BRT CH9 5.05618
580 2FR1 NDP 5.05618
581 5MBX SP5 5.05618
582 5MBX FAD 5.05618
583 5MLR NAP 5.05618
584 5MLR GRQ 5.05618
585 6F7L FAD 5.05618
586 1KEW TYD 5.05618
587 1DLJ UGA 5.05618
588 5BRT FAD 5.05618
589 1DLJ NAI 5.05618
590 4BVA NDP 5.07463
591 4BVA T3 5.07463
592 5CAE SIN 5.11182
593 5CAE COA 5.11182
594 1GUZ NAD 5.16129
595 5T9E NAP 5.16605
596 5T9F TYR 5.16605
597 5T9F NAP 5.16605
598 1EK6 UPG 5.17241
599 1EK6 NAI 5.17241
600 4ITU 1HS 5.20446
601 1F06 NDP 5.3125
602 1F06 2NP 5.3125
603 1HDR NAD 5.32787
604 3CTY FAD 5.32915
605 1MUU NAD 5.33708
606 1MV8 NAD 5.33708
607 1Y8Q ATP 5.33708
608 2HQM FAD 5.33708
609 6EL3 NAP 5.33708
610 5E4R NAP 5.33708
611 1CF2 NAP 5.34125
612 5U5N NAD 5.37634
613 2AE2 PTO 5.38462
614 2AE2 NAP 5.38462
615 4TSK NDP 5.42857
616 2JAC GSH 5.45455
617 3FGZ BEF 5.46875
618 3H9E NAD 5.49133
619 4XDZ NDP 5.53936
620 1DIG NAP 5.55556
621 1DIG L37 5.55556
622 3CBG SAH 5.60345
623 1UWK NAD 5.61798
624 1UWK URO 5.61798
625 1H82 GZZ 5.61798
626 1C0I FAD 5.61798
627 1C0I BE2 5.61798
628 1H82 FAD 5.61798
629 2E5V FAD 5.61798
630 1PS9 FAD 5.61798
631 1PS9 NAP 5.61798
632 2C7G FAD 5.61798
633 1PJS NAD 5.61798
634 2C7G ODP 5.61798
635 1D8C GLV 5.61798
636 5WP5 SAH 5.61798
637 5DOZ NDP 5.6213
638 3Q3C NAD 5.68562
639 1TDF NAP 5.6962
640 1TDF FAD 5.6962
641 1VM6 NAD 5.70175
642 4KWI 1TJ 5.70342
643 4KWI NAP 5.70342
644 2GLX NDP 5.72289
645 1B8U NAD 5.77508
646 1B8U OAA 5.77508
647 5ZW3 SAH 5.77778
648 3O5X JZG 5.7971
649 3OJF IMJ 5.83658
650 3O03 NAP 5.84192
651 6BII NAP 5.89888
652 5MZI FYK 5.89888
653 5MZI FAD 5.89888
654 3RNM FAD 5.89888
655 5G3U FDA 5.89888
656 5G3U ITW 5.89888
657 5FJN BE2 5.89888
658 5FJN FAD 5.89888
659 5ZBC FAD 5.89888
660 4J7U NAP 5.90278
661 4J7U YTZ 5.90278
662 1J5P NAD 5.92885
663 4B7X NAP 5.95238
664 3SJ7 NDP 5.95238
665 4KQW NAP 6
666 2VYN NAD 6.0423
667 1GAD NAD 6.06061
668 4OSP NAP 6.08365
669 3KO8 NAD 6.08974
670 4II2 ATP 6.13497
671 4FC7 COA 6.13718
672 4FC7 NAP 6.13718
673 4J56 FAD 6.14035
674 1F8G NAD 6.17978
675 2GZ3 NAP 6.17978
676 5DN9 NAD 6.17978
677 2NPX NAD 6.17978
678 5Y77 FAD 6.17978
679 1RYD NDP 6.17978
680 1H6C NDP 6.17978
681 1OMO NAD 6.21118
682 5X9D 80F 6.25
683 2F5Z FAD 6.25
684 1LSS NAD 6.42857
685 2OOR NAD 6.46067
686 1BXG NAD 6.46067
687 1BW9 NAD 6.46067
688 1L7E NAI 6.46067
689 1GPE FAD 6.46067
690 1NM5 NAD 6.46067
691 1C1X NAD 6.47887
692 1T26 GBD 6.52174
693 1T26 NAI 6.52174
694 3C1O NAP 6.54206
695 1O94 ADP 6.5625
696 5L4L NAP 6.57895
697 3OID NDP 6.58915
698 6GNA FAD 6.59722
699 5THQ NDP 6.61765
700 5TC4 NAD 6.64557
701 2GN4 UD1 6.68605
702 2GN4 NDP 6.68605
703 3GGO ENO 6.6879
704 3GGO NAI 6.6879
705 5BJX NAD 6.74157
706 5BJX UDP 6.74157
707 5XWC NAP 6.74157
708 5XWC 8GL 6.74157
709 5XWC 2IT 6.74157
710 5ZYN FAD 6.74157
711 1OBB NAD 6.74157
712 3VPH NAD 6.77419
713 3VPH OXM 6.77419
714 2A92 NAI 6.85358
715 4M52 M52 6.86695
716 4M52 FAD 6.86695
717 1WPQ NAD 6.87679
718 4NBW NAD 7.00389
719 5J5Z FAD 7.02247
720 1WDK NAD 7.02247
721 1U8X NAD 7.02247
722 3GD4 NAD 7.02247
723 3G5S FAD 7.02247
724 3GD4 FAD 7.02247
725 1NAA ABL 7.02247
726 5ODQ FAD 7.06522
727 4YAC NAI 7.07071
728 4D3F NAP 7.09677
729 1XSE NDP 7.11864
730 2DC1 NAD 7.20339
731 5A96 GTP 7.22892
732 1HDG NAD 7.22892
733 5YU3 PRO 7.26744
734 5YU3 NAD 7.26744
735 2Y6Q I7T 7.30337
736 2Y6Q FAD 7.30337
737 4PIV NDP 7.30337
738 1NVT NAP 7.31707
739 1JNR FAD 7.33333
740 5MIT FAD 7.33945
741 5MIT NAP 7.33945
742 1P77 ATR 7.35294
743 2G5C NAD 7.47331
744 4EMJ FAD 7.47664
745 1DSS NAD 7.50751
746 5KVA SAM 7.55396
747 3NYC IAR 7.58427
748 3NYC FAD 7.58427
749 2VTD LKM 7.58427
750 1Q1R FAD 7.58427
751 2WET FAD 7.58427
752 2HMT NAI 7.63889
753 4URF NAD 7.66129
754 4MP8 MLI 7.66962
755 4MP8 NAD 7.66962
756 3A28 NAD 7.75194
757 4ZGS NAD 7.86517
758 4XQC NAD 7.86517
759 1HKU NAD 7.86517
760 4XQC 13D 7.86517
761 2GCG NDP 7.87879
762 6AA8 NAD 7.94702
763 3RC1 NAP 8
764 3RC1 TLO 8
765 1LUA NAP 8.01394
766 2II3 CAO 8.01527
767 2DBZ NAP 8.08383
768 1RP0 AHZ 8.09859
769 2DM6 NAP 8.10811
770 2DM6 IMN 8.10811
771 6CI9 NAP 8.10811
772 2ZJ1 ARJ 8.14607
773 2ZJ1 NAD 8.14607
774 1E1M NAP 8.14607
775 1E1M FAD 8.14607
776 1E6E FAD 8.14607
777 4YCA NDP 8.16327
778 3WV8 ATP 8.25688
779 3NGL NAP 8.33333
780 3CH6 NAP 8.39161
781 3CH6 311 8.39161
782 1ZEM NAD 8.39695
783 2VHW NAI 8.42697
784 1GY8 NAD 8.42697
785 5J60 FAD 8.4375
786 1LTH NAD 8.46395
787 3QJ4 FAD 8.47953
788 1M2Z BOG 8.56031
789 2A8X FAD 8.62069
790 2DKN NAI 8.62745
791 3I6I NDP 8.67052
792 3ABI NAD 8.70786
793 2ZXI FAD 8.70786
794 1RYI FAD 8.70786
795 1RYI GOA 8.70786
796 5L95 AMP 8.75
797 5AOV NAP 8.92857
798 1NVM NAD 8.98551
799 1PR9 NAP 9.01639
800 3D3W NAP 9.01639
801 2RH4 EMO 9.02527
802 2RAB NAD 9.26966
803 1MO9 FAD 9.26966
804 2RAB FAD 9.26966
805 1MO9 KPC 9.26966
806 5W3K NDP 9.41177
807 5W3K 9TY 9.41177
808 5A04 NDP 9.43953
809 5A04 BGC 9.43953
810 1P1C SAH 9.54774
811 6AIN FAD 9.55056
812 4TM3 FAD 9.55056
813 2AWN ADP 9.55056
814 3QWI CUE 9.62963
815 3QWI NAP 9.62963
816 1A5Z NAD 9.71787
817 4JDR FAD 9.83146
818 3HAD NAD 10.0649
819 5Z75 NAD 10.0917
820 3DAG FEG 10.1124
821 4YRY NAD 10.1449
822 4YRY FAD 10.1449
823 4E13 NAD 10.2473
824 4RF2 NAP 10.2941
825 2GSD NAD 10.3933
826 6A0S NDP 10.5422
827 6A0S HSE 10.5422
828 2HK9 NAP 10.5455
829 2HK9 ATR 10.5455
830 2AG8 NAP 10.6464
831 4EA7 COA 10.9091
832 4EA7 JB2 10.9091
833 4RSL FAD 11.0112
834 2EV9 NAP 11.0266
835 2EV9 SKM 11.0266
836 5E5U MLI 11.0553
837 5EIN NAP 11.1111
838 1UAY ADN 11.157
839 3AD8 NAD 11.33
840 3AD8 FAD 11.33
841 3AD8 PYC 11.33
842 1I36 NAP 11.3636
843 4JNA FAD 11.4706
844 4YSX FAD 11.5385
845 3GEG NAD 11.7409
846 1LDN NAD 12.0253
847 3QV1 NAD 12.1951
848 4OOE FOM 12.3596
849 4OOE NDP 12.3596
850 4BJZ FAD 12.3596
851 4BJZ P3A 12.3596
852 1VMK GUN 12.6354
853 3LAD FAD 12.6404
854 3WBF API 12.7869
855 3WBF NAP 12.7869
856 3H4V NAP 12.8472
857 3H4V DVP 12.8472
858 5TUF TDC 12.9213
859 2BGM NAJ 12.9213
860 5TUF FAD 12.9213
861 5UAV NDP 13.0435
862 5UAV TFB 13.0435
863 4YAG NAI 13.1488
864 2DT5 NAD 13.7441
865 3GMB FAD 14.0449
866 5HXI 5HN 14.3258
867 5HXI FAD 14.3258
868 1GV0 NAD 14.5161
869 5X68 FAD 14.8338
870 1MXH DHF 15.5797
871 1MXH NAP 15.5797
872 2CFC NAD 16
873 5EOW FAD 16.0112
874 3B6Z CO7 16.8539
875 5ZZ6 NAD 17.7885
876 5ZZ6 ADP 17.7885
877 3K7M FAD 17.9775
878 4NBT NAD 18.3333
879 4OM8 NAD 19.7411
880 3B1J NAD 20
881 5UR0 NAD 21.2034
882 1SAY PYR 21.8837
883 3NJ4 AFX 22.191
884 3NJ4 NAD 22.191
885 4JBI NDP 22.7528
886 5VKT NAP 22.9282
887 2YVJ NAI 23.8532
888 2YVJ FAD 23.8532
889 5FI3 NAP 24.4382
890 3TWO NDP 24.7126
891 2J8Z NAP 26.4045
892 4IDC 1XX 27.1084
893 4IDC NDP 27.1084
894 1KOL NAD 28.9326
895 1N9G NAP 29.2135
896 4WAS NAP 29.2135
897 2GAG NAD 29.2929
898 2GAG FAD 29.2929
899 2GAG FOA 29.2929
900 2B5W NAP 29.7753
901 3JYN NDP 29.8462
902 1KEV NDP 29.9145
903 4Y1B NAP 30.618
904 5O9F NAD 31.5341
905 5O9F 9ON 31.5341
906 1YQD NAP 31.7416
907 5H81 NAP 32.8652
908 1YKF NAP 32.9545
909 4A0S NAP 34.5506
910 4W6Z 8ID 34.8703
911 4W6Z ETF 34.8703
912 1F8F NAD 35.3933
913 1H2B NAJ 35.6742
914 1H2B OCA 35.6742
915 2CDC NAP 35.9551
916 2CDC XYP 35.9551
917 2CDC XYS 35.9551
918 4GKV NAD 36.6071
919 3WLE NAD 37.8299
920 1YB5 NAP 38.7464
921 1LLU NAD 38.8889
922 1P0F NAP 41.2921
923 1D1T NAD 41.573
924 2JHF NAD 42.1348
925 2FZW NAD 42.4157
926 4RQU NAD 42.6966
927 1U3U NAD 42.6966
928 1U3U BNF 42.6966
929 1CDO NAD 42.6966
930 4RVU NDP 43.0723
931 1R37 NAD 43.2277
932 1R37 ETX 43.2277
933 1RJW ETF 43.9528
934 1E3I CXF 44.1011
935 3GFB NAD 47.1429
936 2DFV NAD 47.5504
Pocket No.: 2; Query (leader) PDB : 1PL6; Ligand: 572; Similar sites found with APoc: 84
This union binding pocket(no: 2) in the query (biounit: 1pl6.bio2) has 33 residues
No: Leader PDB Ligand Sequence Similarity
1 2VOH CIT None
2 3OFK SAH None
3 1Z82 NDP 1.49254
4 5W7M SAH 1.60256
5 6BQ6 TER 1.81269
6 6ECU SAH 1.89873
7 1DJL NAP 1.93237
8 3RJ5 NAD 1.9685
9 3G89 SAM 2.00803
10 4JJF N2I 2.32558
11 1XKQ NDP 2.5
12 5MPT SAH 2.52809
13 3FXU TSU 2.62295
14 4CS9 AMP 2.6455
15 1TE2 PGA 2.65487
16 6GNC FAD 2.72109
17 5DNK SAH 2.80899
18 3ZV6 4HB 2.84698
19 3ZV6 NAD 2.84698
20 4IF4 BEF 2.88462
21 3LCC SAH 2.97872
22 3G2O SAM 3.01003
23 1H5R THM 3.07167
24 2JHP SAH 3.08989
25 5E9W SAH 3.20513
26 3JWH SAH 3.22581
27 2JAH NDP 3.23887
28 2JL1 NAP 3.48432
29 5YRI GLC GLC 3.52113
30 4KIB SAH 3.65169
31 5GM1