Receptor
PDB id Resolution Class Description Source Keywords
1QFT 1.25 Å NON-ENZYME: BINDING HISTAMINE BINDING PROTEIN FROM FEMALE BROWN EAR RHIPICEPHALUS APPENDICULATUS RHIPICEPHALUS APPENDICULATUS LIPOCALIN LIGAND BINDING PROTEIN
Ref.: TICK HISTAMINE-BINDING PROTEINS: ISOLATION, CLONING, AND THREE-DIMENSIONAL STRUCTURE. MOL.CELL V. 3 661 1999
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
HSM A:176;
A:177;
B:176;
B:177;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
Kd = 1.7 nM
111.145 C5 H9 N3 c1c(n...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1QFT 1.25 Å NON-ENZYME: BINDING HISTAMINE BINDING PROTEIN FROM FEMALE BROWN EAR RHIPICEPHALUS APPENDICULATUS RHIPICEPHALUS APPENDICULATUS LIPOCALIN LIGAND BINDING PROTEIN
Ref.: TICK HISTAMINE-BINDING PROTEINS: ISOLATION, CLONING, AND THREE-DIMENSIONAL STRUCTURE. MOL.CELL V. 3 661 1999
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 510 families.
1 1QFV - HSM C5 H9 N3 c1c(nc[nH]....
2 1QFT Kd = 1.7 nM HSM C5 H9 N3 c1c(nc[nH]....
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 391 families.
1 1QFV - HSM C5 H9 N3 c1c(nc[nH]....
2 1QFT Kd = 1.7 nM HSM C5 H9 N3 c1c(nc[nH]....
50% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 298 families.
1 1QFV - HSM C5 H9 N3 c1c(nc[nH]....
2 1QFT Kd = 1.7 nM HSM C5 H9 N3 c1c(nc[nH]....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: HSM; Similar ligands found: 2
No: Ligand ECFP6 Tc MDL keys Tc
1 HSM 1 1
2 AHN 0.428571 0.72973
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1QFT; Ligand: HSM; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 1qft.bio1) has 19 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 2; Query (leader) PDB : 1QFT; Ligand: HSM; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 1qft.bio1) has 10 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 3; Query (leader) PDB : 1QFT; Ligand: HSM; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 3) in the query (biounit: 1qft.bio2) has 10 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 4; Query (leader) PDB : 1QFT; Ligand: HSM; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 1qft.bio2) has 20 residues
No: Leader PDB Ligand Sequence Similarity
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