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Receptor
PDB id Resolution Class Description Source Keywords
1R18 2.2 Å EC: 2.1.1.77 DROSOPHILA PROTEIN ISOASPARTYL METHYLTRANSFERASE WITH S-ADEN HOMOCYSTEINE DROSOPHILA MELANOGASTER METHYLTRANSFERASE ISOMERIZATION PROTEIN REPAIR S-ADENOSYLHOMOCYSTEINE TRANSFERASE
Ref.: CATALYTIC IMPLICATIONS FROM THE DROSOPHILA PROTEIN L-ISOASPARTYL METHYLTRANSFERASE STRUCTURE AND SITE-MUTAGENESIS. BIOCHEMISTRY V. 42 12844 2003
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
SAH A:300;
Valid;
none;
submit data
384.411 C14 H20 N6 O5 S c1nc(...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1R18 2.2 Å EC: 2.1.1.77 DROSOPHILA PROTEIN ISOASPARTYL METHYLTRANSFERASE WITH S-ADEN HOMOCYSTEINE DROSOPHILA MELANOGASTER METHYLTRANSFERASE ISOMERIZATION PROTEIN REPAIR S-ADENOSYLHOMOCYSTEINE TRANSFERASE
Ref.: CATALYTIC IMPLICATIONS FROM THE DROSOPHILA PROTEIN L-ISOASPARTYL METHYLTRANSFERASE STRUCTURE AND SITE-MUTAGENESIS. BIOCHEMISTRY V. 42 12844 2003
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 1R18 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 1R18 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
50% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 1I1N - SAH C14 H20 N6 O5 S c1nc(c2c(n....
2 1KR5 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
3 1R18 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: SAH; Similar ligands found: 211
No: Ligand ECFP6 Tc MDL keys Tc
1 SAH 1 1
2 5X8 0.759494 0.969697
3 A7D 0.734177 0.926471
4 TT8 0.709302 0.970588
5 DSH 0.692308 0.914286
6 SXZ 0.692308 0.916667
7 DTA 0.666667 0.857143
8 3DH 0.662338 0.869565
9 S8M 0.655556 0.901408
10 SFG 0.635294 0.954545
11 SA8 0.62069 0.915493
12 EEM 0.617977 0.890411
13 MTA 0.615385 0.869565
14 SAI 0.613636 0.955882
15 S7M 0.586957 0.916667
16 36A 0.586538 0.90411
17 K15 0.583333 0.878378
18 ADN 0.573333 0.84058
19 RAB 0.573333 0.84058
20 XYA 0.573333 0.84058
21 62X 0.572917 0.855263
22 5CD 0.571429 0.852941
23 0UM 0.5625 0.876712
24 5N5 0.558442 0.84058
25 A4D 0.551282 0.867647
26 SAM 0.537634 0.916667
27 SMM 0.536842 0.88
28 SSA 0.536842 0.712644
29 KB1 0.534653 0.902778
30 A5D 0.532609 0.857143
31 SIB 0.53125 0.928571
32 EP4 0.530864 0.819444
33 DSZ 0.530612 0.732558
34 GSU 0.53 0.752941
35 A 0.529412 0.763158
36 LMS 0.529412 0.694118
37 AMP 0.529412 0.763158
38 5CA 0.525773 0.712644
39 ME8 0.524752 0.8125
40 M2T 0.52439 0.821918
41 6RE 0.523256 0.824324
42 GJV 0.522727 0.813333
43 AAT 0.515789 0.863014
44 LSS 0.515152 0.696629
45 KAA 0.514852 0.727273
46 J7C 0.511364 0.835616
47 A5A 0.510417 0.697674
48 SON 0.505495 0.805195
49 SRP 0.505155 0.805195
50 F0P 0.504505 0.915493
51 54H 0.5 0.681818
52 VMS 0.5 0.681818
53 ADX 0.5 0.694118
54 CA0 0.5 0.769231
55 AMO 0.5 0.805195
56 5AL 0.5 0.779221
57 KH3 0.5 0.866667
58 NVA LMS 0.49505 0.707865
59 AHX 0.49505 0.753086
60 TSB 0.494949 0.689655
61 53H 0.494949 0.674157
62 G5A 0.494737 0.712644
63 ABM 0.494382 0.74359
64 A2D 0.494382 0.74359
65 ZAS 0.494253 0.808219
66 A6D 0.490196 0.759494
67 8QN 0.49 0.779221
68 GEK 0.49 0.956522
69 GAP 0.489583 0.769231
70 AN2 0.48913 0.734177
71 A3S 0.48913 0.884058
72 S4M 0.488889 0.831169
73 SRA 0.488636 0.746835
74 LAD 0.485437 0.810127
75 52H 0.484848 0.674157
76 A12 0.483516 0.759494
77 BA3 0.483516 0.74359
78 AP2 0.483516 0.759494
79 NEC 0.483146 0.788732
80 AOC 0.483146 0.842857
81 Y3J 0.481481 0.768116
82 VRT 0.479167 0.861111
83 50T 0.478723 0.734177
84 B4P 0.478261 0.74359
85 ADP 0.478261 0.74359
86 5AS 0.478261 0.655556
87 AP5 0.478261 0.74359
88 A3N 0.477778 0.830986
89 YSA 0.476636 0.712644
90 XAH 0.476636 0.768293
91 0XU 0.473684 0.897059
92 AT4 0.473118 0.7375
93 WAQ 0.471154 0.807692
94 NSS 0.470588 0.712644
95 5AD 0.468354 0.791045
96 AU1 0.468085 0.725
97 M33 0.468085 0.734177
98 MAO 0.467391 0.797468
99 TXA 0.466667 0.759494
100 NB8 0.466667 0.775
101 A3G 0.466667 0.871429
102 3AM 0.465909 0.727273
103 DAL AMP 0.465347 0.779221
104 8X1 0.465347 0.707865
105 A3T 0.463158 0.842857
106 ATP 0.463158 0.74359
107 HEJ 0.463158 0.74359
108 ACP 0.463158 0.746835
109 7D7 0.4625 0.785714
110 LEU LMS 0.461538 0.688889
111 9ZA 0.460784 0.740741
112 9ZD 0.460784 0.740741
113 5FA 0.458333 0.74359
114 AQP 0.458333 0.74359
115 AR6 0.458333 0.766234
116 APC 0.458333 0.759494
117 APR 0.458333 0.766234
118 PRX 0.458333 0.746835
119 F2R 0.457627 0.75
120 IOT 0.456897 0.761905
121 4AD 0.456311 0.794872
122 PAJ 0.456311 0.722892
123 WSA 0.45614 0.72093
124 YAP 0.453704 0.794872
125 8PZ 0.453704 0.712644
126 FA5 0.453704 0.805195
127 ADP PO3 0.453608 0.763158
128 ADV 0.453608 0.782051
129 NVA 2AD 0.453608 0.849315
130 SAP 0.453608 0.728395
131 AGS 0.453608 0.728395
132 RBY 0.453608 0.782051
133 AD9 0.453608 0.725
134 PTJ 0.45283 0.731707
135 MHZ 0.452632 0.797468
136 00A 0.451923 0.740741
137 A3P 0.451613 0.74026
138 YLP 0.451327 0.771084
139 7MD 0.45045 0.768293
140 ALF ADP 0.45 0.707317
141 ADP ALF 0.45 0.707317
142 2VA 0.447917 0.819444
143 OOB 0.446602 0.779221
144 ANP 0.444444 0.725
145 T99 0.444444 0.7375
146 ACQ 0.444444 0.746835
147 TAT 0.444444 0.7375
148 P5A 0.443396 0.719101
149 7D5 0.443182 0.708861
150 A1R 0.442308 0.7625
151 YLC 0.439655 0.790123
152 2AM 0.438202 0.717949
153 DLL 0.438095 0.779221
154 ARG AMP 0.4375 0.759036
155 A22 0.436893 0.734177
156 D3Y 0.436893 0.859155
157 ATF 0.435644 0.716049
158 MYR AMP 0.435185 0.746988
159 80F 0.434426 0.75
160 SO8 0.434343 0.808219
161 OAD 0.433962 0.769231
162 3UK 0.433962 0.769231
163 TAD 0.433628 0.765432
164 25A 0.432692 0.74359
165 6YZ 0.431373 0.746835
166 VO4 ADP 0.431373 0.734177
167 ADP VO4 0.431373 0.734177
168 9SN 0.431193 0.731707
169 TYM 0.431034 0.805195
170 B5V 0.429907 0.759494
171 PR8 0.429907 0.8
172 ADQ 0.428571 0.746835
173 YLB 0.42735 0.771084
174 9K8 0.425926 0.67033
175 1ZZ 0.425926 0.746988
176 FYA 0.425926 0.779221
177 3OD 0.425926 0.769231
178 PPS 0.425743 0.674419
179 MAP 0.423077 0.707317
180 A2P 0.421053 0.727273
181 4YB 0.421053 0.735632
182 9X8 0.420561 0.75
183 ADP BMA 0.420561 0.746835
184 TYR AMP 0.419643 0.794872
185 5SV 0.419048 0.731707
186 3NZ 0.416667 0.824324
187 YLA 0.416667 0.771084
188 8Q2 0.415254 0.688889
189 A3R 0.415094 0.7625
190 B5Y 0.414414 0.75
191 B5M 0.414414 0.75
192 48N 0.413793 0.753086
193 LPA AMP 0.413793 0.768293
194 AYB 0.413223 0.761905
195 ACK 0.413043 0.710526
196 QQY 0.413043 0.696203
197 BIS 0.412844 0.719512
198 JB6 0.412844 0.7625
199 PAP 0.41 0.730769
200 DQV 0.408696 0.75641
201 OVE 0.408602 0.7125
202 AMP DBH 0.40708 0.746835
203 4UV 0.40708 0.75
204 3AD 0.406977 0.852941
205 AF3 ADP 3PG 0.40678 0.743902
206 OMR 0.40678 0.738095
207 LAQ 0.405172 0.768293
208 A A 0.40367 0.74359
209 7C5 0.403509 0.789474
210 7MC 0.403361 0.75
211 4UU 0.4 0.75
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1R18; Ligand: SAH; Similar sites found with APoc: 887
This union binding pocket(no: 1) in the query (biounit: 1r18.bio2) has 24 residues
No: Leader PDB Ligand Sequence Similarity
1 3OFK SAH None
2 2AJH MET None
3 5KK4 44E None
4 6FX2 FUC C4W NAG BMA MAN NAG GAL None
5 2BZ1 TAU 1.02041
6 4YAC NAI 1.32159
7 3H8V ATP 1.32159
8 3VZS NAP 1.32159
9 3VZS CAA 1.32159
10 1W8D NAP 1.32159
11 1W73 NAP 1.32159
12 3QOX SAH 1.76211
13 5MW4 5JU 1.76211
14 4REP FAD 1.76211
15 3MBI HSX 1.76211
16 1L5Y BEF 1.93548
17 5TVI O8N 2.17391
18 6FDF SAH 2.20264
19 3FUU ADN 2.20264
20 1X87 NAD 2.20264
21 2YY7 NAD 2.20264
22 2CDU ADP 2.20264
23 4ITU 1HS 2.20264
24 4ITU NAI 2.20264
25 3FPZ AHZ 2.20264
26 3U31 NAD 2.20264
27 2CDU FAD 2.20264
28 1RKX NAD 2.20264
29 1RLZ NAD 2.20264
30 6A4R ASP 2.20264
31 6F9Q NAD 2.20264
32 4AT0 FAD 2.20264
33 3NJ4 NAD 2.20264
34 3GF4 UPG 2.30769
35 3GF4 FAD 2.30769
36 4JCA CIT 2.39521
37 1V6A TRE 2.40964
38 4R8L ASP 2.5974
39 6ECT SAM 2.64317
40 1YXM ADE 2.64317
41 3S5W FAD 2.64317
42 1YY5 FAD 2.64317
43 1RSG FAD 2.64317
44 1D4D FAD 2.64317
45 5XNC MTA 2.64317
46 3B9Q MLI 2.64317
47 2Q7V FAD 2.64317
48 1H82 FAD 2.64317
49 1H82 GZZ 2.64317
50 1GEG NAD 2.64317
51 6GAS FAD 2.64317
52 1BC5 SAH 2.64317
53 3LXD FAD 2.64317
54 4J1Q NDP 2.64317
55 5L13 6ZE 2.64317
56 2Q1W NAD 2.64317
57 6BWL NAD 2.64317
58 5Z2F PDC 2.64317
59 6AIN FAD 2.64317
60 3SJU NDP 2.64317
61 3OND ADN 2.64317
62 3OND NAD 2.64317
63 1KGZ PRP 2.64317
64 2JK0 ASP 2.64317
65 1U3U NAD 2.64317
66 1U3U BNF 2.64317
67 4J4H NAI 2.64317
68 4J4H 1J1 2.64317
69 4GNC ASO 2.64317
70 5WS9 AMP 2.64317
71 1UAY ADN 2.64317
72 2PS1 ORO 2.65487
73 1M7B GTP 2.71739
74 3DXY SAM 2.75229
75 3WV8 ATP 2.75229
76 1PNO NAP 2.77778
77 1NC2 DOE 2.7907
78 2C5L GTP 2.89017
79 2BES RES 2.90698
80 3EGI ADP 2.91262
81 5KVA SAM 3.0837
82 2WA2 SAM 3.0837
83 3VSE SAH 3.0837
84 5J5Z FAD 3.0837
85 1JQD SAH 3.0837
86 5EEH SAH 3.0837
87 5EEH P9P 3.0837
88 1FEC FAD 3.0837
89 2AOT SAH 3.0837
90 4M52 FAD 3.0837
91 3ICT ADP 3.0837
92 3FRH SAH 3.0837
93 3CGD FAD 3.0837
94 3ICS ADP 3.0837
95 3FSY SCA 3.0837
96 3CGD COA 3.0837
97 5A3B APR 3.0837
98 6H3O FAD 3.0837
99 1JQD HSM 3.0837
100 5LTJ ADP 3.0837
101 2BGM NAJ 3.0837
102 3NTD FAD 3.0837
103 3ICS FAD 3.0837
104 3ICT FAD 3.0837
105 1FUR MLT 3.0837
106 3OZG SSI 3.0837
107 3ICR FAD 3.0837
108 4YKG FAD 3.0837
109 5OC1 FAD 3.0837
110 5T2U NAP 3.0837
111 6GAR FAD 3.0837
112 3B6C SDN 3.0837
113 3NTA FAD 3.0837
114 2A8X FAD 3.0837
115 5TXR PLP 3.0837
116 4RF2 NAP 3.0837
117 5I0H ADP BEF 3.0837
118 5ZYN FAD 3.0837
119 3H4V DVP 3.0837
120 3H4V NAP 3.0837
121 3CGD NAD 3.0837
122 2AF6 BRU 3.0837
123 3CGB FAD 3.0837
124 1V35 NAI 3.0837
125 1UP7 NAD 3.0837
126 1UPF URF 3.125
127 1P19 IMP 3.16742
128 1XTT U5P 3.24074
129 1KMQ GNP 3.26087
130 2JKY 5GP 3.28639
131 4KFU ACP 3.30189
132 1PZM 5GP 3.31754
133 1DJL NAP 3.38164
134 5NM7 GLY 3.38346
135 4KIB SAH 3.52423
136 4M73 M72 3.52423
137 4M73 SAH 3.52423
138 4BLW AMP 3.52423
139 4BLW SAH 3.52423
140 1IM8 SAI 3.52423
141 4OBW SAM 3.52423
142 2O07 SPD 3.52423
143 2O07 MTA 3.52423
144 4KRG SAH 3.52423
145 5M58 SAH 3.52423
146 6BQ6 TER 3.52423
147 1T9D P25 3.52423
148 1T9D PYD 3.52423
149 1T9D 1MM 3.52423
150 5WKC FAD 3.52423
151 1T9D FAD 3.52423
152 4IEE AGS 3.52423
153 4RVG TYD 3.52423
154 5BJX UDP 3.52423
155 5BJX NAD 3.52423
156 4RVG SAM 3.52423
157 1Y8Q ATP 3.52423
158 4N49 SAM 3.52423
159 5K0A FAD 3.52423
160 2J0W ASP 3.52423
161 4PIO AVI 3.52423
162 4YAG NAI 3.52423
163 4PIO SAH 3.52423
164 1I8T FAD 3.52423
165 1VL8 NAP 3.52423
166 5FFF NAP 3.52423
167 3TKY SAH 3.52423
168 2GDZ NAD 3.52423
169 5ICE SAH 3.52423
170 5ICE 2H4 3.52423
171 2AE2 NAP 3.52423
172 5FEU NAP 3.52423
173 5XLX SAH 3.52423
174 4RSL FAD 3.52423
175 1LVL FAD 3.52423
176 2AE2 PTO 3.52423
177 4HA6 FAD 3.52423
178 2VVM FAD 3.52423
179 6FP4 FAD 3.52423
180 4O1M NAD 3.52423
181 5JCM NAD 3.52423
182 5FFF 5XC 3.52423
183 1NVM NAD 3.52423
184 5JCM FAD 3.52423
185 5JCM ISD 3.52423
186 2VVL FAD 3.52423
187 1LVL NAD 3.52423
188 6FP4 E1T 3.52423
189 2VZ0 D64 3.52423
190 2VZ0 NAP 3.52423
191 1R6D NAD 3.52423
192 1R6D DAU 3.52423
193 1RJD SAM 3.52423
194 1S7G APR 3.52423
195 1ZGS XMM 3.52423
196 1S7G NAD 3.52423
197 2WD7 NAP 3.52423
198 4XFM THE 3.52423
199 1JNR FAD 3.52423
200 2R4J 13P 3.52423
201 2R4J FAD 3.52423
202 4J7U YTZ 3.52423
203 3QWI CUE 3.52423
204 4URF NAD 3.52423
205 3QWI NAP 3.52423
206 2JHP SAH 3.52423
207 4J7U NAP 3.52423
208 2JBH 5GP 3.55556
209 3MQ2 SAH 3.66972
210 1D4O NAP 3.80435
211 3ACC 5GP 3.8674
212 1T57 FMN 3.8835
213 2X2T GAL NGA 3.92157
214 3GU3 SAH 3.96476
215 3S1S SAH 3.96476
216 5W7M SAH 3.96476
217 5YF1 8V0 3.96476
218 5YF1 SFG 3.96476
219 3BGD SAH 3.96476
220 3GWZ SAH 3.96476
221 3BGD PM6 3.96476
222 2BZG SAH 3.96476
223 5U8U FAD 3.96476
224 4PPF FLC 3.96476
225 4EUE NAI 3.96476
226 5WGR FAD 3.96476
227 5MBX SP5 3.96476
228 5MBX FAD 3.96476
229 3GEG NAD 3.96476
230 3QJ4 FAD 3.96476
231 3AB1 FAD 3.96476
232 5TTJ FAD 3.96476
233 3LZW NAP 3.96476
234 3LZW FAD 3.96476
235 5KMS NAD 3.96476
236 3BMN NAP 3.96476
237 5K6A NAP 3.96476
238 2XTZ GSP 3.96476
239 3AY6 BGC 3.96476
240 4CM9 NAP 3.96476
241 1OC2 NAD 3.96476
242 1OC2 TDX 3.96476
243 1GY8 NAD 3.96476
244 2DKH 3HB 3.96476
245 2DKH FAD 3.96476
246 4GKV NAD 3.96476
247 4CMI NAP 3.96476
248 1I2B USQ 3.96476
249 1I2B NAD 3.96476
250 1I2B UPG 3.96476
251 3JQB NAP 3.96476
252 4CM8 NAP 3.96476
253 5KMS FAD 3.96476
254 5JCJ NAP 3.96476
255 1V8K ANP 3.96476
256 4CME NAP 3.96476
257 3JQ8 NAP 3.96476
258 5JDC NAP 3.96476
259 2V6G NAP 3.96476
260 3HQP FDP 3.96476
261 2ZJ1 ARJ 3.96476
262 3GXO SAH 3.96476
263 3JQF NAP 3.96476
264 3JQG NAP 3.96476
265 4CM4 NAP 3.96476
266 1NJR XYL 3.96476
267 4CNK FAD 3.96476
268 5YB7 FAD 3.96476
269 3JQ9 NAP 3.96476
270 5JDI NAP 3.96476
271 3JQ7 NAP 3.96476
272 4CLR NAP 3.96476
273 3BMO NAP 3.96476
274 5YB7 ORN 3.96476
275 3AY6 NAI 3.96476
276 2ZJ1 NAD 3.96476
277 4CLO NAP 3.96476
278 3A28 NAD 3.96476
279 3JQA NAP 3.96476
280 3BMQ NAP 3.96476
281 5K7U SAM 4
282 5G3L SIA 4.0404
283 4HXY NDP 4.10959
284 4JGP PYR 4.14747
285 2ZFU SAH 4.18605
286 5IL1 SAM 4.24528
287 5VJN IR8 4.27807
288 4O0L NDP 4.36364
289 4FZV SAM 4.40529
290 1NW5 SAM 4.40529
291 6ARJ BW4 4.40529
292 6ARJ SAH 4.40529
293 5DX8 SFG 4.40529
294 5DWQ SFG 4.40529
295 3G2O SAM 4.40529
296 5DXA SFG 4.40529
297 5DX1 SFG 4.40529
298 5DX0 SFG 4.40529
299 3BXO SAM 4.40529
300 5GWX SAR 4.40529
301 5GWX SAM 4.40529
302 5FTW SAH 4.40529
303 4RPL FAD 4.40529
304 4RPL 3UC 4.40529
305 1YQZ FAD 4.40529
306 5Z75 NAD 4.40529
307 1BZL GCG 4.40529
308 2RAB NAD 4.40529
309 2GN4 NDP 4.40529
310 2RAB FAD 4.40529
311 1BZL FAD 4.40529
312 2GN4 UD1 4.40529
313 1ORR NAD 4.40529
314 1O5O U5P 4.40529
315 6CI9 NAP 4.40529
316 2C5A GDC 4.40529
317 2C5A NAD 4.40529
318 3MAG SAH 4.40529
319 3MCT SAH 4.40529
320 4GUT FAD 4.40529
321 5G3U FDA 4.40529
322 4FN4 NAD 4.40529
323 3QVP FAD 4.40529
324 2C31 TZD 4.40529
325 2C31 ADP 4.40529
326 1QO8 FAD 4.40529
327 4FWE FAD 4.40529
328 5MIT FAD 4.40529
329 5MIT NAP 4.40529
330 4C3Y FAD 4.40529
331 5EZ7 FAD 4.40529
332 1XHC FAD 4.40529
333 4C3Y ANB 4.40529
334 4TXI FAD 4.40529
335 1GTE FAD 4.40529
336 5K4W NAI 4.40529
337 5K4W THR 4.40529
338 6EQS BV8 4.40529
339 1QK3 5GP 4.40529
340 2C7G FAD 4.40529
341 2C7G ODP 4.40529
342 3D3W NAP 4.40529
343 5DNK SAH 4.40529
344 2WKQ GTP 4.40529
345 1RP0 AHZ 4.40529
346 5DF1 58X 4.40529
347 5DF1 NAP 4.40529
348 5FJN BE2 4.40529
349 5FJN FAD 4.40529
350 5G3U ITW 4.40529
351 3RIY NAD 4.40529
352 4LJ9 ACP 4.40529
353 1PR9 NAP 4.40529
354 2PZM UDP 4.40529
355 2PZM NAD 4.40529
356 4GLL NAD 4.40529
357 5YEC ATP 4.40529
358 4POO SAM 4.5
359 3HVJ 705 4.52489
360 4BQS ADP 4.54545
361 3GDH SAH 4.56432
362 2F5Z FAD 4.6875
363 3OZ2 FAD 4.78589
364 1DCP HBI 4.80769
365 2ZIF SAM 4.84582
366 5HJM MTA 4.84582
367 6B92 SAH 4.84582
368 6GFK SAH 4.84582
369 3PFG TLO 4.84582
370 3PFG SAM 4.84582
371 3G89 SAM 4.84582
372 6ECU SAH 4.84582
373 1V5F FAD 4.84582
374 1V5F TPP 4.84582
375 4AZW SAM 4.84582
376 2EG5 SAH 4.84582
377 4MO2 FDA 4.84582
378 2FK8 SAM 4.84582
379 4MO2 FAD 4.84582
380 2PX8 SAH 4.84582
381 1KPG SAH 4.84582
382 1DQN IMU 4.84582
383 3I53 SAH 4.84582
384 1TD2 PXL 4.84582
385 1ELI PYC 4.84582
386 5J60 FAD 4.84582
387 6F97 FAD 4.84582
388 4BV6 FAD 4.84582
389 4YNU FAD 4.84582
390 1M2K APR 4.84582
391 1ZGA SAH 4.84582
392 5I39 FAD 4.84582
393 1U1I NAD 4.84582
394 1V8B NAD 4.84582
395 2WOX NDP 4.84582
396 4Z24 FAD 4.84582
397 3AFN NAP 4.84582
398 5ZW3 SAH 4.88889
399 4RHY 3QG 4.97512
400 5L95 AMP 5
401 4RL4 PPV 5.18868
402 4C4A SAH 5.28634
403 2VDV SAM 5.28634
404 4Y30 SAH 5.28634
405 4Y30 49L 5.28634
406 4LWP SAH 5.28634
407 5WP5 SAH 5.28634
408 3ELW SAM 5.28634
409 3ELW GP3 5.28634
410 2P41 SAH 5.28634
411 3EVG SAH 5.28634
412 3TKA SAM 5.28634
413 2YX1 SFG 5.28634
414 4PNE SAH 5.28634
415 3SQP FAD 5.28634
416 6D6Y SAH 5.28634
417 3C6K SPD 5.28634
418 3C6K MTA 5.28634
419 1MO9 FAD 5.28634
420 1MO9 KPC 5.28634
421 3O7W SAM 5.28634
422 3AD8 NAD 5.28634
423 5GWT NAD 5.28634
424 5GWT SIN 5.28634
425 5E8J SAH 5.28634
426 5E9W SAH 5.28634
427 3ZFD ANP 5.28634
428 1XHL NDP 5.28634
429 4U8P UDP 5.28634
430 4U8P FDA 5.28634
431 4G5H UD7 5.28634
432 4G5H NAP 5.28634
433 5M67 NAD 5.28634
434 5M67 3D1 5.28634
435 1NAA 6FA 5.28634
436 1NAA ABL 5.28634
437 5M67 ADE 5.28634
438 1E1M NAP 5.28634
439 1E1M FAD 5.28634
440 1LVK MNT BEF 5.28634
441 4D04 FAD 5.28634
442 4D04 NAP 5.28634
443 6CA4 MLI 5.28634
444 1RRC ADP 5.28634
445 6B5G NAD 5.28634
446 2ZUX RAM 5.28634
447 1XG5 NAP 5.28634
448 1E3W NAD 5.28634
449 1E6W NAD 5.28634
450 6B5G CQY 5.28634
451 1WY7 SAH 5.31401
452 3O5N BR0 5.35714
453 1MXH DHF 5.43478
454 1MXH NAP 5.43478
455 3FZG SAM 5.5
456 4XFR CIT 5.62061
457 5E72 SAM 5.72687
458 3PT9 SAH 5.72687
459 1F3L SAH 5.72687
460 2HNK SAH 5.72687
461 5WP4 SAH 5.72687
462 4KGD TDP 5.72687
463 4KGD FAD 5.72687
464 5GVR LMR 5.72687
465 1GET FAD 5.72687
466 1GET NAP 5.72687
467 4EMI FAD 5.72687
468 4EMI NAD 5.72687
469 3AYI HCI 5.72687
470 3AYI FAD 5.72687
471 4EMJ FAD 5.72687
472 1NM5 NAD 5.72687
473 4NTD FAD 5.72687
474 1NM5 NAP 5.72687
475 3LU1 NAD 5.72687
476 6FHO FAD 5.72687
477 5BUK FAD 5.72687
478 1AE1 NAP 5.72687
479 6ER9 FAD 5.72687
480 6ER9 NAP 5.72687
481 5ME4 HP4 5.72687
482 4YSX FAD 5.72687
483 3FG2 FAD 5.72687
484 1G0N PHH 5.72687
485 1G0N NDP 5.72687
486 1WVG APR 5.72687
487 1L3I SAH 5.72917
488 2XYQ SAH 5.7377
489 2HQM FAD 5.84551
490 4JLS 3ZE 5.92105
491 3QFA FAD 6.03448
492 2PXX SAH 6.04651
493 1N2X SAM 6.1674
494 1XCL SAH 6.1674
495 5UFN SAH 6.1674
496 2UYQ SAM 6.1674
497 1YBH FAD 6.1674
498 6DEN FAD 6.1674
499 6DEN G8A 6.1674
500 6DEN TP9 6.1674
501 5BW4 SAM 6.1674
502 4L2I FAD 6.1674
503 4UCI SAM 6.1674
504 2JB2 FAD 6.1674
505 2JB2 PHE 6.1674
506 3HDY GDU 6.1674
507 3HDY FDA 6.1674
508 3HDY FAD 6.1674
509 4TQG NDP 6.1674
510 3P9C SAH 6.1674
511 1YBH P22 6.1674
512 1WD4 AHR 6.1674
513 3SSO SAH 6.1674
514 5ZRR 9J3 6.1674
515 3ZV6 4HB 6.1674
516 3ZV6 NAD 6.1674
517 5C9P FUC 6.1674
518 1XKQ NDP 6.1674
519 2B9W FAD 6.1674
520 4CQM NAP 6.1674
521 1XSE NDP 6.1674
522 5JCA FAD 6.1674
523 2ZWA SAH 6.1674
524 4B2D FBP 6.1674
525 5VN0 FAD 6.1674
526 2BD0 NAP 6.1674
527 5JCA NDP 6.1674
528 3HB5 NAP 6.1674
529 5VN0 NAI 6.1674
530 2Y6Q I7T 6.1674
531 2Y6Q FAD 6.1674
532 3CH6 NAP 6.1674
533 3CH6 311 6.1674
534 5ZZ6 ADP 6.25
535 1OIX GDP 6.28272
536 3L4N GSH 6.29921
537 2OOR TXP 6.32184
538 1NRJ GTP 6.42202
539 4P83 U5P 6.59341
540 4ONQ SFG 6.60793
541 3LKZ SFG 6.60793
542 1O97 FAD 6.60793
543 1O97 AMP 6.60793
544 3M6W SAM 6.60793
545 6ECW SAH 6.60793
546 2HXW FLC 6.60793
547 5NMX NAP 6.60793
548 3U4C NDP 6.60793
549 5NMX FAD 6.60793
550 2HMT NAI 6.60793
551 4ZCC FAD 6.60793
552 4ZCC NAI 6.60793
553 2EWM NAD 6.60793
554 3UOY NAP 6.60793
555 3UOY FAD 6.60793
556 3WDM ADN 6.60793
557 4U00 ADP 6.60793
558 3IHG FAD 6.60793
559 1OAA OAA 6.60793
560 1O94 ADP 6.60793
561 1BXK NAD 6.60793
562 2JAH NDP 6.88259
563 1CXZ GSP 6.97674
564 2HV8 GTP 6.97674
565 1P1C SAH 7.03518
566 1SQF SAM 7.04846
567 5MPT SAH 7.04846
568 1UWK URO 7.04846
569 1UWK NAD 7.04846
570 2PT9 2MH 7.04846
571 2PT9 S4M 7.04846
572 1V59 FAD 7.04846
573 2I7C AAT 7.04846
574 3RNM FAD 7.04846
575 4JDR FAD 7.04846
576 1BW9 NAD 7.04846
577 3E1T FAD 7.04846
578 5O42 NAD 7.04846
579 5O42 BGC 7.04846
580 5O42 9JW 7.04846
581 2YVF FAD 7.04846
582 2YVF NAD 7.04846
583 6F7L FAD 7.04846
584 1KYZ SAH 7.04846
585 2BRY FAD 7.04846
586 4OPC PGT 7.04846
587 1V59 NAD 7.04846
588 4OPC FDA 7.04846
589 3AKI AH8 7.04846
590 1UDB UFG 7.04846
591 1UDB NAD 7.04846
592 4MOP 2H5 7.04846
593 2YVJ FAD 7.04846
594 1KYZ FER 7.04846
595 3A4V NAD 7.04846
596 2YVJ NAI 7.04846
597 3A4V PYR 7.04846
598 2CDN ADP 7.46269
599 2EJU SAH 7.48899
600 4NEC SAH 7.48899
601 3LCC SAH 7.48899
602 3A25 SAM 7.48899
603 5JGL SAM 7.48899
604 2OBF SAH 7.48899
605 2OBF F83 7.48899
606 2IVD FAD 7.48899
607 2Z3Y F2N 7.48899
608 4B63 FAD 7.48899
609 4B63 NAP 7.48899
610 4B63 ORN 7.48899
611 2Q28 ADP 7.48899
612 1FP2 SAH 7.48899
613 4D7E FAD 7.48899
614 1MZV AMP 7.48899
615 2GV8 FAD 7.48899
616 2GVC FAD 7.48899
617 4AOA IK2 7.48899
618 3GD4 FAD 7.48899
619 3GD4 NAD 7.48899
620 3ABI NAD 7.48899
621 1FP2 HMO 7.48899
622 1VQW FAD 7.48899
623 4USR FAD 7.48899
624 3AXB FAD 7.48899
625 3AXB PRO 7.48899
626 1D7O TCL 7.48899
627 1D7O NAD 7.48899
628 6EL3 NAP 7.48899
629 3WYF GTP 7.48899
630 1TX4 ALF GDP 7.57576
631 1Q0S SAH 7.72201
632 5JJR SAH 7.92952
633 5CUQ NSC 7.92952
634 5BSZ SAH 7.92952
635 3CBG SAH 7.92952
636 4D5G TPP 7.92952
637 4D5G FAD 7.92952
638 4YRY FAD 7.92952
639 1BDB NAD 7.92952
640 6AR9 3L4 7.92952
641 4RDH AMP 7.92952
642 5TWB FAD 7.92952
643 3OID NDP 7.92952
644 4XQC 13D 7.92952
645 6AM8 TRP 7.92952
646 4XQC NAD 7.92952
647 4IP7 FBP 7.92952
648 4YRY NAD 7.92952
649 4JNA FAD 7.92952
650 1Q1R FAD 7.92952
651 4RDI ATP 7.92952
652 6BCA GSP 7.94702
653 1FL2 FAD 8.06452
654 4QTU SAM 8.17308
655 1GWN GTP 8.29268
656 2PWY SAH 8.37004
657 2DPM SAM 8.37004
658 5ULP KB1 8.37004
659 1EFV FAD 8.37004
660 1EFV AMP 8.37004
661 5YJF SAH 8.37004
662 5JE0 SAH 8.37004
663 5JE0 AZ8 8.37004
664 3EYA FAD 8.37004
665 5JAQ NAI 8.37004
666 3KLJ FAD 8.37004
667 4NBU NAI 8.37004
668 3NKS FAD 8.37004
669 1SB8 NAD 8.37004
670 1SB8 UD2 8.37004
671 4II2 ATP 8.37004
672 4TM3 FAD 8.37004
673 5EB4 FAD 8.37004
674 4E3Q PMP 8.37004
675 2YIV NBN 8.37004
676 1U7T TDT 8.37004
677 4D79 ATP 8.37004
678 1KYQ NAD 8.37004
679 1W7J ADP BEF 8.37004
680 5YJF 8WO 8.37004
681 4RDN 6MD 8.38323
682 4HDO GNP 8.38323
683 3X1Z GNP 8.38323
684 1E6E FAD 8.59375
685 5W7K SAH 8.81057
686 3DMH GMP 8.81057
687 3DMH SAM 8.81057
688 3A27 SAM 8.81057
689 5DLY 5D7 8.81057
690 5DLY SAH 8.81057
691 2IID PHE 8.81057
692 2IID FAD 8.81057
693 1PN0 FAD 8.81057
694 1PN0 IPH 8.81057
695 1IY8 NAD 8.81057
696 4FC7 NAP 8.81057
697 4FC7 COA 8.81057
698 2XVE FAD 8.81057
699 2XVF FAD 8.81057
700 5KOX FAD 8.81057
701 5KOX RFP 8.81057
702 3KO8 NAD 8.81057
703 2G77 AF3 9.09091
704 5U19 827 9.2511
705 5U19 SAH 9.2511
706 4KRI SAH 9.2511
707 5MGZ SAH 9.2511
708 2EFJ SAH 9.2511
709 5BVA FAD 9.2511
710 5N0J FAD 9.2511
711 4IV9 FAD 9.2511
712 3NUG NAD 9.2511
713 4AP3 NAP 9.2511
714 4AP3 FAD 9.2511
715 2FR1 NDP 9.2511
716 6C8R EQV 9.49868
717 6C8R SAH 9.49868
718 2GAG NAD 9.52381
719 5FUB SAH 9.69163
720 1JQ3 AAT 9.69163
721 5LOG SAH 9.69163
722 1XTP SAI 9.69163
723 1FP1 SAH 9.69163
724 5T67 SAH 9.69163
725 5T67 JHZ 9.69163
726 5BRT FAD 9.69163
727 5BRT CH9 9.69163
728 3NYC IAR 9.69163
729 3NYC FAD 9.69163
730 2RGO FAD 9.69163
731 2DKN NAI 9.69163
732 2ZXI FAD 9.69163
733 4EIP FAD 9.69163
734 4K5S FAD 9.69163
735 1HGX 5GP 9.83607
736 1EJ0 SAM 10
737 6BYF CIT 10
738 4E70 N7I 10.0515
739 3OU2 SAH 10.0917
740 4YMH SAH 10.1322
741 3GRU AMP 10.1322
742 1U2Z SAH 10.1322
743 3VYW SAM 10.1322
744 4DMG SAM 10.1322
745 5FWA J7C 10.1322
746 2WSB NAD 10.1322
747 1GPE FAD 10.1322
748 1PJS NAD 10.1322
749 3KC1 2T6 10.1322
750 1WA5 GTP 10.1322
751 3A4M ADP 10.1322
752 4Q9N NAI 10.1322
753 2IZ1 ATR 10.1322
754 4LHW GNP 10.3448
755 4J56 FAD 10.5263
756 5KOK SAH 10.5727
757 1ZQ9 SAM 10.5727
758 5KOK R9T 10.5727
759 5KOK S9T 10.5727
760 2NVK FAD 10.5727
761 5HSA FAS 10.5727
762 5OJI NAP 10.5727
763 5OJI ISN 10.5727
764 4USQ FAD 10.5727
765 3Q87 SAM 10.5882
766 3LN9 FLC 10.7914
767 5THZ SAH 10.8642
768 5THY SAH 10.8642
769 4Y9D NAI 11.0132
770 1ZEM NAD 11.0132
771 2YG3 FAD 11.0132
772 4ZG4 VO4 ADP 11.0132
773 5ODQ FAD 11.413
774 1G60 SAM 11.4537
775 6GKV SAH 11.4537
776 2A14 SAH 11.4537
777 5YJI SAH 11.4537
778 5YJI 8WO 11.4537
779 1ZK7 FAD 11.4537
780 4MIG G3F 11.4537
781 1COY FAD 11.4537
782 1QB7 ADE 11.4537
783 4P86 5GP 11.4754
784 5DI9 GNP 11.8881
785 1G55 SAH 11.8943
786 4IWN GEK 11.8943
787 3GCZ SAM 11.8943
788 5GM1 SAH 11.8943
789 5X62 SAH 11.8943
790 4DSG FAD 11.8943
791 4DSG UDP 11.8943
792 3LCV SAM 11.8943
793 5GSN MMZ 11.8943
794 5GSN FAD 11.8943
795 5GSN NAP 11.8943
796 4HAT GNP 12.1429
797 1NF3 GNP 12.3077
798 3LAD FAD 12.3348
799 5TS5 FAD 12.3348
800 3WMX NAD 12.3348
801 4X9M FAD 12.3348
802 1G6H ADP 12.3348
803 4K81 GTP 12.3348
804 4XUC 43G 12.3853
805 4XUC SAM 12.3853
806 3P2E SAH 12.4444
807 2XVM SAH 12.5628
808 2NGR GDP 12.5654
809 1I9G SAM 12.7753
810 3MB5 SAM 12.7753
811 2NXE SAM 12.7753
812 1KPH SAH 12.7753
813 2WET FAD 12.7753
814 5KQA GSH 12.8788
815 3JWH SAH 12.9032
816 5ERG SAM 13.2159
817 1L1E SAH 13.2159
818 4A6D SAM 13.2159
819 3GDN FAD 13.2159
820 3GDN HBX 13.2159
821 1LSS NAD 13.5714
822 1WG8 SAM 13.6564
823 4GQB 0XU 13.6564
824 4X60 3XV 13.6564
825 4X60 SFG 13.6564
826 1Z3C SA8 13.6564
827 5FA5 MTA 13.6564
828 1EDO NAP 13.6564
829 5FA8 SAM 13.6646
830 6BCB GSP 13.6986
831 3EVF SAH 14.0969
832 3EVF GTA 14.0969
833 3VC1 SAH 14.0969
834 3VC1 GST 14.0969
835 5E1M SAH 14.0969
836 5E1M PRO PRO LYS ARG ILE ALA 14.0969
837 3RKR NAP 14.1221
838 1QAN SAH 14.5374
839 6F5Z SAH 14.5374
840 2JJQ SAH 14.5374
841 2JAC GSH 14.5455
842 1JJV ATP 14.5631
843 2W2X GSP 14.5946
844 3T7S SAM 14.978
845 6B3A SAM 14.978
846 5TUF TDC 14.978
847 5TUF FAD 14.978
848 1NNU TCT 15
849 1NNU NAD 15
850 2DTX BMA 15.1515
851 2WPF FAD 15.4185
852 2WPF WPF 15.4185
853 1TPY SAH 15.859
854 3A4T SFG 16.2996
855 3LST SAH 16.2996
856 3NDJ SAH 17.6211
857 3NDJ JHZ 17.6211
858 3L9W AMP 18.0617
859 3L9W GSH 18.0617
860 6C5B SAH 18.5022
861 5DM1 SAH 18.9427
862 5DM1 5D7 18.9427
863 4DCM SAM 18.9427
864 3X0D SAH 19.8238
865 2VT3 ATP 20
866 1VE3 SAM 20.2643
867 3TLJ SAH 20.7048
868 1QZZ SAM 20.7048
869 1XDS SAM 22.0264
870 3OBT SLB 22.0264
871 4YUW 4JU 22.467
872 4YUW S4M 22.467
873 3H2B SAH 22.6601
874 6DUB SAH 23.4234
875 3DUW SAH 24.2152
876 1P0Z FLC 24.4275
877 5F8F SFG 24.6696
878 3C3Y SAH 25.1101
879 1NV8 MEQ 25.9912
880 1NV8 SAM 25.9912
881 4M37 SAH 29.5154
882 4M38 SAH 29.5154
883 4R6W PC 29.9559
884 4R6W SAH 29.9559
885 3FPF TNA 31.2775
886 3FPF MTA 31.2775
887 5N5D SAM 32.7434
Pocket No.: 2; Query (leader) PDB : 1R18; Ligand: SAH; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 1r18.bio2) has 24 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 3; Query (leader) PDB : 1R18; Ligand: SAH; Similar sites found with APoc: 5
This union binding pocket(no: 3) in the query (biounit: 1r18.bio1) has 24 residues
No: Leader PDB Ligand Sequence Similarity
1 1KEV NDP 3.52423
2 4UP5 94W 5.05051
3 2NUO BGC 5.7377
4 5X3R 7Y3 6.82927
5 4K5S PM0 9.69163
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