Receptor
PDB id Resolution Class Description Source Keywords
1R6N 2.4 Å NON-ENZYME: TRANSCRIPT_TRANSLATE HPV11 E2 TAD COMPLEX CRYSTAL STRUCTURE HUMAN PAPILLOMAVIRUS TYPE 11 PAPILLOMAVIRUS; E2 TAD; TAD; X-RAY STRUCTURE; TRANSCRIPTION;REPLICATION TRANSCRIPTION REPLICATION
Ref.: CRYSTAL STRUCTURE OF THE E2 TRANSACTIVATION DOMAIN PAPILLOMAVIRUS TYPE 11 BOUND TO A PROTEIN INTERACTI INHIBITOR J.BIOL.CHEM. V. 279 6976 2004
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
434 A:1111;
A:1112;
Valid;
Valid;
none;
none;
Kd = 40 nM
608.449 C29 H19 Cl2 N3 O6 S Cc1cc...
ALQ A:1113;
Invalid;
none;
submit data
88.105 C4 H8 O2 CC(C)...
DMS A:1114;
Invalid;
none;
submit data
78.133 C2 H6 O S CS(=O...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1R6N 2.4 Å NON-ENZYME: TRANSCRIPT_TRANSLATE HPV11 E2 TAD COMPLEX CRYSTAL STRUCTURE HUMAN PAPILLOMAVIRUS TYPE 11 PAPILLOMAVIRUS; E2 TAD; TAD; X-RAY STRUCTURE; TRANSCRIPTION;REPLICATION TRANSCRIPTION REPLICATION
Ref.: CRYSTAL STRUCTURE OF THE E2 TRANSACTIVATION DOMAIN PAPILLOMAVIRUS TYPE 11 BOUND TO A PROTEIN INTERACTI INHIBITOR J.BIOL.CHEM. V. 279 6976 2004
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 291 families.
1 1R6N Kd = 40 nM 434 C29 H19 Cl2 N3 O6 S Cc1ccc2c(c....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 247 families.
1 1R6N Kd = 40 nM 434 C29 H19 Cl2 N3 O6 S Cc1ccc2c(c....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 209 families.
1 1R6N Kd = 40 nM 434 C29 H19 Cl2 N3 O6 S Cc1ccc2c(c....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: 434; Similar ligands found: 1
No: Ligand ECFP6 Tc MDL keys Tc
1 434 1 1
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1R6N; Ligand: 434; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 1r6n.bio1) has 12 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 2; Query (leader) PDB : 1R6N; Ligand: 434; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 1r6n.bio1) has 9 residues
No: Leader PDB Ligand Sequence Similarity
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