Receptor
PDB id Resolution Class Description Source Keywords
1RSZ 2.2 Å EC: 2.4.2.1 STRUCTURE OF HUMAN PURINE NUCLEOSIDE PHOSPHORYLASE IN COMPLE DADME-IMMUCILLIN-H AND SULFATE HOMO SAPIENS PNP TRANSITION-STATE ANALOGUE TRANSFERASE
Ref.: STRUCTURAL COMPARISON OF HUMAN AND MALARIAL PURINE NUCLEOSIDE PHOSPHORYLASES TO BE PUBLISHED
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
DIH A:300;
Valid;
none;
submit data
267.304 C12 H19 N4 O3 C1[C@...
SO4 A:401;
A:402;
A:403;
Invalid;
Invalid;
Invalid;
none;
none;
none;
submit data
96.063 O4 S [O-]S...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2A0W 2.28 Å EC: 2.4.2.1 STRUCTURE OF HUMAN PURINE NUCLEOSIDE PHOSPHORYLASE H257G MUT HOMO SAPIENS PURINE NUCLEOSIDE PHOSPHORYLASE TRANSITION STATE INHIBITORTRANSFERASE
Ref.: NEIGHBORING GROUP PARTICIPATION IN THE TRANSITION S HUMAN PURINE NUCLEOSIDE PHOSPHORYLASE. BIOCHEMISTRY V. 46 5038 2007
Members (10)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 16 families.
1 2ON6 Ki = 172 nM IMH C11 H14 N4 O4 c1c(c2c([n....
2 2A0Y Ki = 900 pM DIH C12 H19 N4 O3 C1[C@@H]([....
3 1RR6 - IMH C11 H14 N4 O4 c1c(c2c([n....
4 2A0X Ki = 950 pM DIH C12 H19 N4 O3 C1[C@@H]([....
5 3GB9 - A2F C5 H4 F N5 c1[nH]c2c(....
6 1RT9 - IMH C11 H14 N4 O4 c1c(c2c([n....
7 5UGF - IM5 C12 H17 N5 O3 c1c(c2c([n....
8 3BGS Ki = 380 pM DIH C12 H19 N4 O3 C1[C@@H]([....
9 1RSZ - DIH C12 H19 N4 O3 C1[C@@H]([....
10 2A0W Ki = 270 pM DIH C12 H19 N4 O3 C1[C@@H]([....
70% Homology Family (30)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 9 families.
1 2ON6 Ki = 172 nM IMH C11 H14 N4 O4 c1c(c2c([n....
2 2A0Y Ki = 900 pM DIH C12 H19 N4 O3 C1[C@@H]([....
3 1RR6 - IMH C11 H14 N4 O4 c1c(c2c([n....
4 2A0X Ki = 950 pM DIH C12 H19 N4 O3 C1[C@@H]([....
5 3GB9 - A2F C5 H4 F N5 c1[nH]c2c(....
6 1RT9 - IMH C11 H14 N4 O4 c1c(c2c([n....
7 5UGF - IM5 C12 H17 N5 O3 c1c(c2c([n....
8 3BGS Ki = 380 pM DIH C12 H19 N4 O3 C1[C@@H]([....
9 1RSZ - DIH C12 H19 N4 O3 C1[C@@H]([....
10 2A0W Ki = 270 pM DIH C12 H19 N4 O3 C1[C@@H]([....
11 1B8O Ki = 23 pM IMH C11 H14 N4 O4 c1c(c2c([n....
12 1A9T - R1P C5 H11 O8 P C([C@@H]1[....
13 1VFN Ki = 2.5 uM HPA C5 H4 N4 O c1[nH]c2c(....
14 2QPL ic50 = 18.9 uM BTY C6 H7 N5 O Cc1cc2n(n1....
15 2AI1 ic50 = 300 nM P1G C12 H16 N5 O8 P c1nc2c(n1[....
16 1B8N Ki = 30 pM IMG C11 H15 N5 O4 c1c(c2c([n....
17 1A9S - NOS C10 H12 N4 O5 c1nc2c(n1[....
18 2AI3 ic50 = 5000 nM P2G C11 H14 N5 O8 P c1nc2c(n1[....
19 1LVU Kd = 4.8 uM 9PP C9 H13 N6 O4 P C[C@@H](Cn....
20 1A9P - 9DI C11 H13 N3 O5 c1c(c2c([n....
21 2AI2 ic50 = 30 nM P1D C13 H16 N3 O8 P c1c(c2c([n....
22 1V48 Ki = 16 nM HA1 C10 H14 F2 N5 O4 P c1nc2c(n1C....
23 1A9Q - HPA C5 H4 N4 O c1[nH]c2c(....
24 3FUC Kd = 190 pM 9D9 9DG n/a n/a
25 1A9R - HPA C5 H4 N4 O c1[nH]c2c(....
26 1LV8 Kd = 3.5 uM 9PP C9 H13 N6 O4 P C[C@@H](Cn....
27 1FXU - GU7 C10 H16 N6 O3 c1nc2c(n1C....
28 4EAR - IM5 C12 H17 N5 O3 c1c(c2c([n....
29 5ETJ Kd = 66 pM IM5 C12 H17 N5 O3 c1c(c2c([n....
30 4EB8 - IM5 C12 H17 N5 O3 c1c(c2c([n....
50% Homology Family (41)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 2ON6 Ki = 172 nM IMH C11 H14 N4 O4 c1c(c2c([n....
2 2A0Y Ki = 900 pM DIH C12 H19 N4 O3 C1[C@@H]([....
3 1RR6 - IMH C11 H14 N4 O4 c1c(c2c([n....
4 2A0X Ki = 950 pM DIH C12 H19 N4 O3 C1[C@@H]([....
5 3GB9 - A2F C5 H4 F N5 c1[nH]c2c(....
6 1RT9 - IMH C11 H14 N4 O4 c1c(c2c([n....
7 5UGF - IM5 C12 H17 N5 O3 c1c(c2c([n....
8 3BGS Ki = 380 pM DIH C12 H19 N4 O3 C1[C@@H]([....
9 1RSZ - DIH C12 H19 N4 O3 C1[C@@H]([....
10 2A0W Ki = 270 pM DIH C12 H19 N4 O3 C1[C@@H]([....
11 1B8O Ki = 23 pM IMH C11 H14 N4 O4 c1c(c2c([n....
12 1A9T - R1P C5 H11 O8 P C([C@@H]1[....
13 1VFN Ki = 2.5 uM HPA C5 H4 N4 O c1[nH]c2c(....
14 2QPL ic50 = 18.9 uM BTY C6 H7 N5 O Cc1cc2n(n1....
15 2AI1 ic50 = 300 nM P1G C12 H16 N5 O8 P c1nc2c(n1[....
16 1B8N Ki = 30 pM IMG C11 H15 N5 O4 c1c(c2c([n....
17 1A9S - NOS C10 H12 N4 O5 c1nc2c(n1[....
18 2AI3 ic50 = 5000 nM P2G C11 H14 N5 O8 P c1nc2c(n1[....
19 1LVU Kd = 4.8 uM 9PP C9 H13 N6 O4 P C[C@@H](Cn....
20 1A9P - 9DI C11 H13 N3 O5 c1c(c2c([n....
21 2AI2 ic50 = 30 nM P1D C13 H16 N3 O8 P c1c(c2c([n....
22 1V48 Ki = 16 nM HA1 C10 H14 F2 N5 O4 P c1nc2c(n1C....
23 1A9Q - HPA C5 H4 N4 O c1[nH]c2c(....
24 3FUC Kd = 190 pM 9D9 9DG n/a n/a
25 1A9R - HPA C5 H4 N4 O c1[nH]c2c(....
26 1LV8 Kd = 3.5 uM 9PP C9 H13 N6 O4 P C[C@@H](Cn....
27 1FXU - GU7 C10 H16 N6 O3 c1nc2c(n1C....
28 5IFK - HPA C5 H4 N4 O c1[nH]c2c(....
29 4EAR - IM5 C12 H17 N5 O3 c1c(c2c([n....
30 5ETJ Kd = 66 pM IM5 C12 H17 N5 O3 c1c(c2c([n....
31 4EB8 - IM5 C12 H17 N5 O3 c1c(c2c([n....
32 2P4S Kd = 0.42 nM DIH C12 H19 N4 O3 C1[C@@H]([....
33 3FB1 - R1P C5 H11 O8 P C([C@@H]1[....
34 3E9R - ADE C5 H5 N5 c1[nH]c2c(....
35 3E0Q - JFD C4 H4 Br N3 O2 C1(=C(NC(=....
36 3FNQ - HPA C5 H4 N4 O c1[nH]c2c(....
37 3FAZ - NOS C10 H12 N4 O5 c1nc2c(n1[....
38 3IEX - GMP C10 H13 N5 O5 c1nc2c(n1[....
39 3DJF ic50 = 0.8 uM BC3 C12 H11 N5 O c1cc(cnc1)....
40 3F8W - ADN C10 H13 N5 O4 c1nc(c2c(n....
41 1VMK - GUN C5 H5 N5 O c1[nH]c2c(....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: DIH; Similar ligands found: 1
No: Ligand ECFP6 Tc MDL keys Tc
1 DIH 1 1
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2A0W; Ligand: DIH; Similar sites found: 427
This union binding pocket(no: 1) in the query (biounit: 2a0w.bio1) has 24 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1BTN I3P 0.0007537 0.53921 None
2 1SS4 GSH 0.004964 0.49269 None
3 1UO5 PIH 0.00479 0.48601 None
4 1OGD RIP 0.001728 0.45443 None
5 3I8T LBT 0.004161 0.43754 None
6 3UEC ALA ARG TPO LYS 0.01035 0.43622 None
7 1YRX FMN 0.002176 0.42978 None
8 1SS4 CIT 0.01646 0.42588 None
9 3F8C HT1 0.01131 0.4232 None
10 2IYG FMN 0.004338 0.42223 None
11 3KPE TM3 0.0227 0.41415 None
12 2E1A MSE 0.0165 0.4066 None
13 3PMD 11A 0.01511 0.40411 None
14 3R51 MMA 0.008504 0.45426 1.25
15 3MAG 3MA 0.04077 0.42454 1.38408
16 1I2L DCS 0.004923 0.40103 1.48699
17 3E5H GNP 0.001276 0.40765 1.68539
18 1O9U ADZ 0.005629 0.46375 1.7301
19 4MOB ADP 0.0002231 0.46072 1.7301
20 2OWZ CIT 0.005358 0.44391 1.7301
21 3U1T MLI 0.009575 0.43789 1.7301
22 2W8Q SIN 0.01006 0.43684 1.7301
23 2Q8M AMP 0.002787 0.43002 1.7301
24 4QDC ASD 0.0001738 0.42622 1.7301
25 3DER ALA LYS 0.001442 0.41623 1.7301
26 4B7E OGA 0.01796 0.41398 1.7301
27 1SJD NPG 0.001167 0.4089 1.7301
28 4OB6 S2T 0.009536 0.40079 1.7301
29 2Y7P SAL 0.002641 0.44628 1.83486
30 3EJ0 11X 0.0005096 0.48125 2.04082
31 2NZ2 ASP 0.0001364 0.50318 2.07612
32 2EJU SAH 0.0003927 0.44441 2.07612
33 2F2U M77 0.00193 0.44142 2.07612
34 2Z9V PXM 0.003532 0.44069 2.07612
35 1WDA BAG 0.003572 0.43521 2.07612
36 4NAO AKG 0.01195 0.43316 2.07612
37 1RY2 AMP 0.00001427 0.41898 2.07612
38 1ML4 PAL 0.0008418 0.41519 2.07612
39 2YP9 SIA CMO 0.004356 0.41192 2.07612
40 4IMG NGF 0.002479 0.41161 2.07612
41 3SHR CMP 0.01443 0.40495 2.07612
42 1FBL HTA 0.0153 0.40389 2.07612
43 1LL2 UPG 0.003542 0.40271 2.07612
44 2BS5 BGC GAL FUC 0.0003778 0.4211 2.22222
45 2PR5 FMN 0.003148 0.41152 2.27273
46 1Q6O LG6 0.001714 0.4294 2.31481
47 3TKA CTN 0.004241 0.48505 2.42215
48 1A5Z OXM 0.001728 0.48217 2.42215
49 4B9E FAH 0.001798 0.47347 2.42215
50 1V6A TRE 0.0009343 0.47273 2.42215
51 1A5Z FBP 0.0005296 0.43539 2.42215
52 3L24 GOA 0.01962 0.43499 2.42215
53 4TSK NDP 0.0001867 0.42977 2.42215
54 3DGB MUC 0.003042 0.42848 2.42215
55 1T26 GBD 0.00129 0.42398 2.42215
56 1T26 NAI 0.00129 0.42398 2.42215
57 1H6W SER LEU ASN TYR ILE ILE LYS VAL LYS GLU 0.0003268 0.41669 2.42215
58 2Y7G AAE 0.004508 0.41329 2.42215
59 1CKM GTP 0.002228 0.41326 2.42215
60 4EPL JAI 0.005288 0.41063 2.42215
61 2C5S AMP 0.01574 0.40748 2.42215
62 3TKA SAM 0.00279 0.4063 2.42215
63 2JFV FLC 0.03733 0.4038 2.42215
64 1OMZ UD2 0.0007245 0.40133 2.42215
65 2GJ3 FAD 0.000007635 0.43629 2.5
66 3LTW HLZ 0.01461 0.42325 2.5
67 1MZV AMP 0.01035 0.411 2.55319
68 3PNA CMP 0.007699 0.42087 2.5974
69 1EJE FMN 0.004466 0.40599 2.60417
70 2EB5 OXL 0.001671 0.46783 2.62172
71 4AF5 CIT 0.001971 0.46444 2.63158
72 1EYQ NAR 0.008482 0.41906 2.7027
73 1JCM 137 0.000286 0.41463 2.7027
74 3FPZ AHZ 0.00003883 0.46471 2.76817
75 1PEA ACM 0.004201 0.46257 2.76817
76 1A59 CIT 0.005573 0.44942 2.76817
77 4RJK PYR 0.008006 0.44833 2.76817
78 1Z6K OAA 0.002694 0.43296 2.76817
79 1A59 COA 0.0008906 0.43148 2.76817
80 3QO8 SSA 0.00167 0.42983 2.76817
81 4C6F DOR 0.008159 0.41531 2.76817
82 4C6F NCD 0.008159 0.41531 2.76817
83 1YBH FAD 0.002287 0.41291 2.76817
84 1QZZ SAM 0.006206 0.41183 2.76817
85 4N02 FNR 0.0006099 0.41115 2.76817
86 2IMP NAI 0.002297 0.40951 2.76817
87 1WRA PC 0.04572 0.40432 2.76817
88 4P87 4NP 0.001113 0.40318 2.76817
89 3DG6 MUC 0.01105 0.40194 2.76817
90 3BY8 MLT 0.01405 0.42971 2.8169
91 4JP3 CIT 0.002055 0.43538 2.92887
92 1A8S PPI 0.00007947 0.49576 2.9304
93 3NOJ PYR 0.0003981 0.48607 2.94118
94 4AP9 1PS 0.0001478 0.45505 2.98507
95 1QH9 LAC 0.01282 0.42596 3.01724
96 4HZO COA 0.001464 0.45762 3.11419
97 2CE7 ADP 0.0008968 0.44493 3.11419
98 2VAR KDF 0.001396 0.44218 3.11419
99 3MMR ABH 0.0001257 0.43615 3.11419
100 2WL9 MBD 0.0001799 0.43507 3.11419
101 4M51 BEZ 0.02047 0.42752 3.11419
102 3P7I P7I 0.008395 0.42402 3.11419
103 2VAR AMP 0.006078 0.42065 3.11419
104 4A3R CIT 0.0000908 0.4165 3.11419
105 2NVK NAP 0.01379 0.41444 3.11419
106 1G6O ADP 0.0006311 0.41408 3.11419
107 3NNF AKG 0.02502 0.41213 3.11419
108 2GGH NLQ 0.0000869 0.40948 3.11419
109 2VAR ANP 0.0031 0.40472 3.11419
110 2C9O ADP 0.0003088 0.40441 3.11419
111 1YHM AHD 0.02968 0.40391 3.11419
112 1Z45 UPG 0.00539 0.40302 3.11419
113 2Z1U ATP 0.008485 0.40274 3.11419
114 2VHJ ADP 0.005013 0.40075 3.11419
115 3MB5 SAM 0.0006958 0.40769 3.13725
116 1EYE PMM 0.00702 0.41376 3.21429
117 3PHQ KDO 0.0182 0.4559 3.22581
118 4COQ SAN 0.008914 0.43344 3.23887
119 1NXJ TLA 0.0001723 0.46496 3.27869
120 1NXJ GLV 0.004769 0.42981 3.27869
121 1GU3 BGC BGC BGC BGC BGC 0.01284 0.41582 3.3557
122 3BHO B4P 0.008656 0.46197 3.36538
123 1FNZ A2G 0.00081 0.42112 3.37553
124 1FS5 TLA 0.0004302 0.41423 3.38346
125 2QCX PF1 0.007456 0.43151 3.42205
126 4F8L GAL 0.008376 0.47199 3.44828
127 1XE7 GUN 0.01977 0.43481 3.44828
128 1ONX ASP 0.00007375 0.43949 3.46021
129 3CEV ARG 0.00303 0.43828 3.46021
130 3GJB AKG 0.005861 0.42597 3.46021
131 3OYZ ACO 0.00001999 0.42036 3.46021
132 4GQB 0XU 0.000388 0.41687 3.46021
133 3LM9 ADP 0.01068 0.40635 3.46021
134 2CJH AKG 0.006854 0.4063 3.46021
135 3WE0 FAD 0.000488 0.40616 3.46021
136 2DVZ GLU 0.01405 0.40544 3.46021
137 1LTH NAD 0.001158 0.40305 3.46021
138 2BOI MFU 0.00855 0.42367 3.53982
139 4LKK SIA GAL 0.0002817 0.44966 3.57143
140 1NHZ 486 0.002585 0.40409 3.57143
141 4JCA CIT 0.002651 0.49032 3.59281
142 1Y9Q MED 0.01421 0.42383 3.64583
143 3H86 AP5 0.001313 0.40188 3.64583
144 4IEN GDP 0.000222 0.42298 3.68098
145 1AX2 NDG GAL 0.001999 0.45163 3.76569
146 1KYV RBF 0.004846 0.4083 3.77358
147 2GN2 C5P 0.003664 0.41284 3.80117
148 1Z42 HBA 0.003637 0.49975 3.80623
149 1Z48 FMN 0.0004573 0.45138 3.80623
150 1Z41 FMN 0.0004935 0.45011 3.80623
151 1Z44 NPO 0.02416 0.44528 3.80623
152 3O2K QRP 0.00209 0.43998 3.80623
153 1Z42 FMN 0.001584 0.43995 3.80623
154 1T10 F6P 0.005302 0.43828 3.80623
155 4PB2 5UD 0.0005889 0.43801 3.80623
156 4C2G ALA ALA ALA ALA 0.005208 0.42817 3.80623
157 4M5P MLA 0.03537 0.42801 3.80623
158 4M5P FMN 0.0008098 0.4249 3.80623
159 1Z44 FMN 0.004937 0.41575 3.80623
160 3O2K DST 0.01319 0.41531 3.80623
161 4J7H TLO 0.001549 0.41515 3.80623
162 3PLN U5P 0.02554 0.4025 3.80623
163 2F59 INI 0.003377 0.41042 3.82166
164 2Y6P CTP 0.003567 0.4303 3.84615
165 3DX5 DHB 0.005157 0.42363 3.84615
166 3KYF 5GP 5GP 0.001987 0.44089 3.8961
167 1D09 PAL 0.006554 0.40578 3.92157
168 1QR0 COA 0.003833 0.429 3.94737
169 4F4S EFO 0.0282 0.40057 3.94737
170 2V5E SCR 0.005461 0.47301 3.9604
171 1ULE GLA GAL NAG 0.0172 0.43139 4
172 1J2Z SOG 0.0006759 0.44253 4.07407
173 3LGS ADE 0.0004774 0.54805 4.11985
174 3LGS SAH 0.003556 0.47866 4.11985
175 3OIG NAD 0.0002379 0.42836 4.13534
176 3B9Z CO2 0.0003866 0.49783 4.15225
177 1Q3Q ANP 0.00002889 0.45371 4.15225
178 2Q1A 2KT 0.0000883 0.45363 4.15225
179 2FGQ MLT 0.006229 0.44082 4.15225
180 4W6Z ETF 0.01653 0.43895 4.15225
181 2P69 PLP 0.005612 0.43715 4.15225
182 1DXY COI 0.01926 0.43542 4.15225
183 4Q3S X7A 0.00008994 0.43493 4.15225
184 4UAL 3FV 0.0009988 0.43392 4.15225
185 1ZED PNP 0.01992 0.42223 4.15225
186 1HV9 UD1 0.00007296 0.42172 4.15225
187 3TFC PEP 0.01021 0.42024 4.15225
188 2YYJ 4HP 0.001309 0.4183 4.15225
189 2YYJ FAD 0.001309 0.4183 4.15225
190 2HNK SAH 0.001963 0.41521 4.15225
191 1VDC FAD 0.0003422 0.41465 4.15225
192 3JQ3 ADP 0.009222 0.41309 4.15225
193 2IZ1 ATR 0.03293 0.40642 4.15225
194 4PNO U5P 0.006189 0.41188 4.16667
195 3VHZ L2P GLC MAN SGA 0.002714 0.40141 4.19847
196 4TMK T5A 0.004716 0.41172 4.22535
197 3S9K CIT 0.002776 0.4962 4.23729
198 1I9G SAM 0.00005111 0.43608 4.28571
199 4LN7 1ZQ 0.004466 0.40963 4.30622
200 2PMP C5P 0.008105 0.40726 4.375
201 1F7K UMP 0.002114 0.40215 4.41176
202 2DTJ THR 0.00106 0.45227 4.49438
203 3K3G MMU 0.0003711 0.48744 4.49827
204 1RYD GLC 0.0009594 0.4792 4.49827
205 1TV5 ORO 0.0001646 0.46572 4.49827
206 1TV5 N8E 0.0001098 0.46453 4.49827
207 2ZJ5 ADP 0.002878 0.45041 4.49827
208 4L7I SAM 0.003086 0.41562 4.49827
209 1C7S CBS 0.009281 0.40883 4.49827
210 2AEB ABH 0.0001785 0.40647 4.49827
211 1OFH ADP 0.001552 0.40337 4.5977
212 2JGS BTN 0.01347 0.41726 4.61538
213 1VQ2 DDN 0.003565 0.41328 4.66321
214 3VGL BGC 0.0001519 0.42273 4.6729
215 1B55 4IP 0.006626 0.41071 4.73373
216 4LO6 SIA GAL 0.0002107 0.52364 4.73684
217 4NVP 7CH 0.0001342 0.40489 4.78469
218 3I51 45C 0.002606 0.4312 4.81482
219 1H65 GDP 0.003301 0.40377 4.81482
220 4IVG ANP 0.0000418 0.44298 4.84429
221 1V5F TPP 0.001919 0.43431 4.84429
222 1V5F FAD 0.001919 0.43431 4.84429
223 3W54 RNB 0.004069 0.41906 4.84429
224 1H16 PYR 0.03138 0.41798 4.84429
225 2NLI LAC 0.001199 0.40085 4.84429
226 2NLI FMN 0.001199 0.40085 4.84429
227 3Q9T FAY 0.0004857 0.40058 4.84429
228 2WIC GNP 0.000594 0.42013 4.86891
229 4JEJ 1GP 0.0005059 0.46001 4.91803
230 3F81 STT 0.0226 0.42531 4.91803
231 1UW1 ADP 0.006347 0.43471 5
232 3I6B KDO 0.007918 0.42515 5
233 1LVL NAD 0.002104 0.41055 5.02183
234 1YOA FMN 0.0434 0.43039 5.03145
235 1YOA FAD 0.002659 0.40368 5.03145
236 1O68 KIV 0.003222 0.44246 5.09091
237 1QO0 BMD 0.02424 0.41279 5.10204
238 1C1L GAL BGC 0.01628 0.42655 5.10949
239 4DN8 BMA 0.001493 0.47013 5.12821
240 1GJW GLC 0.002647 0.46524 5.19031
241 4IU0 ABH 0.0001117 0.45019 5.19031
242 3L6R MLI 0.0101 0.43674 5.19031
243 2Q3M MLA 0.02065 0.4338 5.19031
244 1NML CIT 0.0059 0.43082 5.19031
245 4KCT PYR 0.005336 0.42772 5.19031
246 3T1A 5MA 0.001326 0.4252 5.19031
247 2GWD GLU 0.006925 0.42285 5.19031
248 1SQ5 PAU 0.009367 0.42191 5.19031
249 2Q09 DI6 0.0121 0.41241 5.19031
250 1SQ5 ADP 0.008404 0.41059 5.19031
251 1K6M AGS 0.00317 0.40109 5.19031
252 1GJW MAL 0.01842 0.4005 5.19031
253 4M7F BM3 0.004152 0.41872 5.30973
254 1KYQ NAD 0.002424 0.41566 5.47445
255 2B7N NTM 0.01567 0.4167 5.49451
256 1I0Z OXM 0.002915 0.47885 5.53633
257 3A1I UNU 0.0003377 0.47294 5.53633
258 2PP3 LGT 0.0003667 0.41635 5.53633
259 4AF0 MOA 0.001142 0.4092 5.53633
260 2R5T ANP 0.002128 0.40694 5.53633
261 1E4E PHY 0.008578 0.40256 5.53633
262 1F8F NAD 0.00147 0.40169 5.53633
263 1A27 EST 0.009528 0.4008 5.53633
264 2QLX RM4 0.01435 0.42926 5.55556
265 1SJW NGV 0.002775 0.42137 5.55556
266 3MD0 GDP 0.005247 0.42803 5.6338
267 4B16 NAG 0.02101 0.44063 5.6391
268 1S8F GDP 0.004381 0.4178 5.64972
269 1XIU REA 0.001569 0.42659 5.65217
270 2ZSC BTN 0.003053 0.42398 5.67376
271 3NJQ NJQ 0.0003906 0.41719 5.69948
272 4KGM ATP 0.0008564 0.45076 5.71429
273 1MQ0 BRD 0.004886 0.41593 5.71429
274 1L3I SAH 0.001257 0.40155 5.72917
275 1JA9 NDP 0.0002017 0.43682 5.83942
276 4FFS BIG 0.000001035 0.51294 5.85774
277 3FS8 TDR 0.000563 0.42529 5.86081
278 9LDT OXM 0.002692 0.48995 5.88235
279 3P0F BAU 0.00013 0.47229 5.88235
280 1O7N IND 0.00002774 0.47061 5.88235
281 2BO4 FLC 0.002826 0.46386 5.88235
282 3VCA PRO 0.001745 0.45724 5.88235
283 4NTX AMR 0.002145 0.45321 5.88235
284 1GPJ CIT 0.01103 0.42905 5.88235
285 4CMF PXG 0.0001575 0.42633 5.88235
286 4QDF 30Q 0.0002764 0.42008 5.88235
287 2BH9 NAP 0.003409 0.41794 5.88235
288 2QS8 MET 0.00005578 0.41043 5.88235
289 1LDM OXM 0.01099 0.40991 5.88235
290 1JSH SIA GAL 0.002421 0.40505 5.88235
291 2RCN GDP 0.01567 0.40345 5.88235
292 4A8H PUW 0.000492 0.40315 5.88235
293 1V7R CIT 0.0167 0.44617 5.91398
294 4Q3F TLA 0.001235 0.47402 5.98291
295 1G8S MET 0.01428 0.42373 6.08696
296 1SC3 MLI 0.02976 0.41917 6.17978
297 4WBD CIT 0.008778 0.44629 6.22837
298 3E5P PPI 0.02894 0.43469 6.22837
299 1QW9 KHP 0.0001545 0.43333 6.22837
300 1H0C AOA 0.01673 0.42597 6.22837
301 4WBD ADP 0.03129 0.41253 6.22837
302 1Y7P RIP 0.04112 0.41192 6.27803
303 3GM5 CIT 0.01688 0.42028 6.28931
304 1ZJ6 G3D 0.001808 0.43763 6.41711
305 2PVQ GSH 0.00247 0.41924 6.46766
306 2FH5 GTP 0.003245 0.40746 6.48649
307 3SCH TB6 0.0143 0.4237 6.56566
308 1ZZ7 S0H 0.0183 0.40897 6.56566
309 2NCD ADP 0.003553 0.44623 6.57439
310 3I8P 840 0.002976 0.42021 6.57439
311 2Q37 3AL 0.0231 0.40894 6.62983
312 1F5F DHT 0.001677 0.42551 6.82927
313 4K30 NLG 0.007858 0.4253 6.875
314 2DWU DGL 0.01334 0.41058 6.88406
315 1I1Q TRP 0.003087 0.43793 6.92042
316 3R6K FUC GAL GLA 0.01485 0.42852 6.92042
317 5EQU AKG 0.04602 0.40939 6.92042
318 2HMT NAI 0.000392 0.41296 6.94444
319 1FX8 BOG 0.0006005 0.44216 7.11744
320 3UWB BB2 0.01814 0.41879 7.14286
321 1QDS PGA 0.0066 0.41916 7.17131
322 1NF8 BOG 0.01918 0.42305 7.24638
323 1NF8 ISC 0.009371 0.40866 7.24638
324 4G1V FAD 0.002331 0.41624 7.26644
325 3SQG COM 0.001405 0.50551 7.61246
326 4CCN OGA 0.005721 0.44256 7.61246
327 4CCO OGA 0.006839 0.42797 7.61246
328 4M37 SAH 0.001678 0.41763 7.61246
329 2Z5Y HRM 0.0002567 0.41601 7.61246
330 1ODJ GMP 0.003143 0.47713 7.65957
331 3QDT A2G GAL 0.002234 0.4765 7.69231
332 3QDY A2G GAL 0.006008 0.45467 7.69231
333 3QDY CBS 0.01162 0.43375 7.69231
334 3RO7 TDR 0.006837 0.40122 7.92453
335 4OYA 1VE 0.0004724 0.44008 7.95848
336 2A2X NA9 0.003816 0.40848 8.10811
337 2O66 FLC 0.00524 0.43852 8.14815
338 1UGX GAL MGC 0.0002136 0.41836 8.27068
339 3CF6 SP1 0.00421 0.41443 8.38323
340 2ZO9 MLI 0.00004349 0.5065 8.39416
341 3KJQ B94 0.01524 0.40007 8.42105
342 1Y2W NAG 0.002226 0.46194 8.4507
343 1MVQ MMA 0.0004901 0.40173 8.47458
344 3TA2 AKG 0.0001165 0.40123 8.47458
345 3E81 SLB 0.01213 0.42181 8.53659
346 1QD0 RR6 0.01096 0.4059 8.59375
347 3NGU ADP 0.001434 0.4369 8.60927
348 2BLE 5GP 0.00005616 0.44701 8.65052
349 1FWE HAE 0.002372 0.44284 8.65052
350 1X8X TYR 0.003783 0.42924 8.65052
351 1PX8 XYP 0.02684 0.40592 8.65052
352 1LYX PGA 0.001051 0.44221 8.87097
353 2Q8H TF4 0.01501 0.44117 8.99654
354 3I0O SMI 0.01483 0.41781 8.99654
355 1E2S CSN 0.006272 0.41165 8.99654
356 2OFD NGA 0.001989 0.46424 9.15493
357 2OFE NAG 0.0283 0.40957 9.15493
358 3CH5 GDP 0.004183 0.42288 9.25926
359 1Y42 TYR 0.004175 0.43747 9.34256
360 2QF7 COA 0.00662 0.41073 9.34256
361 1KTC NGA 0.01826 0.40901 9.34256
362 2VQ5 LDP 0.004609 0.46834 9.45274
363 2VQ5 HBA 0.005248 0.4507 9.45274
364 1A5V Y3 0.0002232 0.50111 9.49367
365 4EXO PYR 0.03862 0.41333 9.58904
366 2HJ3 FAD 0.002472 0.40812 9.6
367 4U9W COA 0.006271 0.40411 9.66184
368 1RZM E4P 0.0004364 0.50352 9.68858
369 3ZGE ASP 0.01611 0.43284 9.68858
370 1I2B USQ 0.001571 0.43123 9.68858
371 1I2B NAD 0.001571 0.43123 9.68858
372 1I2B UPG 0.001571 0.43123 9.68858
373 1RZM PEP 0.009745 0.42115 9.68858
374 1GSA ADP 0.0003718 0.41362 9.68858
375 4DYO SD4 0.01455 0.40896 9.68858
376 1GSA GSH 0.0003584 0.40773 9.68858
377 2X61 NGA GAL SIA 0.0001854 0.42986 9.68992
378 2X61 CH 0.00005297 0.42833 9.68992
379 1QY1 PRZ 0.0008551 0.42409 9.77011
380 2Q28 ADP 0.004564 0.4022 10.0346
381 2C2A ADP 0.003975 0.41152 10.0775
382 2J5S KTA 0.001953 0.41908 10.2662
383 1ZFJ IMP 0.0003806 0.44205 10.3806
384 2HVK TBA 0.001421 0.47115 10.5023
385 3BK2 U5P 0.01039 0.40685 10.7266
386 4QAR ADE 0.007953 0.45581 10.9453
387 1Q3P GLU ALA GLN THR ARG LEU 0.01924 0.40371 11.0092
388 4IXW IXW 0.01615 0.407 11.0236
389 2YLD CMO 0.04206 0.40131 11.0236
390 2YIV YIV 0.01431 0.43547 11.0727
391 1ZOS MTM 0.01607 0.43616 11.3043
392 1B74 DGN 0.003208 0.46852 11.4173
393 2ZX7 ZX7 0.0001414 0.4186 11.4187
394 4WVH ASP HIS ASP ALA HIS ALA 0.01734 0.40567 11.4187
395 1NVU GTP 0.0001969 0.4273 11.4458
396 1JGS SAL 0.002651 0.50084 11.5942
397 2FOI JPA 0.006283 0.42005 11.6667
398 1WKL ATP 0.0007536 0.43412 11.6788
399 1Y75 NAG 0.00142 0.45239 11.8644
400 1XX4 BAM 0.000695 0.4752 11.8774
401 1H8P PC 0.005237 0.46541 11.9266
402 2WMO GTP 0.002111 0.43029 12.1053
403 1JOT GAL A2G 0.00007311 0.5006 12.782
404 2VKL MLT 0.006865 0.46753 13.3333
405 1NU4 MLA 0.002199 0.44425 13.4021
406 3RF4 FUN 0.001206 0.46134 13.7931
407 2XDQ MGX 0.003494 0.47469 13.8408
408 1ECM TSA 0.001919 0.44679 14.6789
409 1DL7 NCH 0.03151 0.43855 14.6789
410 2BZ1 TAU 0.0003731 0.54992 14.7959
411 4LHM AZZ 0.02649 0.40619 14.8789
412 1H2M OGA 0.004419 0.44787 15.3846
413 4G28 0W8 0.02059 0.40244 15.4362
414 1R6W 164 0.006747 0.40656 16.263
415 1UCN ADP 0.0104 0.40297 16.4474
416 1UO4 PIH 0.0128 0.45256 17.6471
417 3KMT SAH 0.002233 0.42933 18.4874
418 1WNG SAH 0.003262 0.40738 19.2453
419 2FR6 URI 0.002613 0.41447 19.863
420 2FR6 CTN 0.00431 0.40656 19.863
421 5DRN 5CT 0.0193 0.43892 20.8333
422 1T0S BML 0.03435 0.41596 24.2215
423 3EW2 BTN 0.0007425 0.46447 25.9259
424 4GLJ RHB 0.0000000003212 0.56962 31.4879
425 3BL6 FMC 0.0000004018 0.42166 32.6087
426 5F7J ADE 0.0001915 0.521 36.3322
427 1K27 MTM 2.842e-16 0.73677 44.1696
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