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Receptor
PDB id Resolution Class Description Source Keywords
1S7G 2.3 Å EC: 3.5.1.- STRUCTURAL BASIS FOR THE MECHANISM AND REGULATION OF SIR2 ENZYMES ARCHAEOGLOBUS FULGIDUS ENZYME SIRTUIN SIR2 NAD+ ADP-RIBOSE TRANSCRIPTION
Ref.: STRUCTURAL BASIS FOR THE MECHANISM AND REGULATION OF SIR2 ENZYMES MOL.CELL V. 13 639 2004
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
1PE A:504;
Invalid;
none;
submit data
238.278 C10 H22 O6 C(COC...
2PE B:501;
Invalid;
none;
submit data
414.488 C18 H38 O10 C(COC...
APR E:704;
Valid;
none;
submit data
559.316 C15 H23 N5 O14 P2 c1nc(...
EDO A:505;
B:507;
B:508;
Invalid;
Invalid;
Invalid;
none;
none;
none;
submit data
62.068 C2 H6 O2 C(CO)...
NAD A:703;
B:701;
C:702;
Valid;
Valid;
Valid;
none;
none;
none;
submit data
663.425 C21 H27 N7 O14 P2 c1cc(...
P6G C:502;
Invalid;
none;
submit data
282.331 C12 H26 O7 C(COC...
PG4 C:506;
D:503;
Invalid;
Invalid;
none;
none;
submit data
194.226 C8 H18 O5 C(COC...
SO4 A:401;
A:405;
A:407;
A:412;
B:402;
B:404;
B:409;
B:410;
C:406;
C:411;
D:403;
D:408;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
submit data
96.063 O4 S [O-]S...
ZN A:601;
A:602;
B:603;
B:604;
C:605;
C:606;
D:607;
D:608;
E:609;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
none;
none;
none;
none;
none;
none;
none;
none;
none;
submit data
65.409 Zn [Zn+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1S7G 2.3 Å EC: 3.5.1.- STRUCTURAL BASIS FOR THE MECHANISM AND REGULATION OF SIR2 ENZYMES ARCHAEOGLOBUS FULGIDUS ENZYME SIRTUIN SIR2 NAD+ ADP-RIBOSE TRANSCRIPTION
Ref.: STRUCTURAL BASIS FOR THE MECHANISM AND REGULATION OF SIR2 ENZYMES MOL.CELL V. 13 639 2004
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 31 families.
1 1S7G - APR C15 H23 N5 O14 P2 c1nc(c2c(n....
2 1YC2 - APR C15 H23 N5 O14 P2 c1nc(c2c(n....
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 28 families.
1 1S7G - APR C15 H23 N5 O14 P2 c1nc(c2c(n....
2 1YC2 - APR C15 H23 N5 O14 P2 c1nc(c2c(n....
50% Homology Family (18)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 209 families.
1 4BUZ - OAD C17 H25 N5 O15 P2 CC(=O)O[C@....
2 3D4B - THR SER ARG HIS LYS ALY LEU MET ALA n/a n/a
3 3D81 - SER ARG HIS LYS FZN LEU MET PHE n/a n/a
4 1S5P Kd = 0.44 uM LYS GLY GLY ALA ALY ARG HIS ARG n/a n/a
5 1M2K - APR C15 H23 N5 O14 P2 c1nc(c2c(n....
6 1M2J - APR C15 H23 N5 O14 P2 c1nc(c2c(n....
7 1M2G - APR C15 H23 N5 O14 P2 c1nc(c2c(n....
8 1ICI - NAD C21 H27 N7 O14 P2 c1cc(c[n+]....
9 1M2H - APR C15 H23 N5 O14 P2 c1nc(c2c(n....
10 6EQS - BV8 C47 H63 N11 O19 P2 S CC(C)NC(=O....
11 2NYR - SVR C51 H40 N6 O23 S6 Cc1ccc(cc1....
12 4G1C - CNA C22 H30 N7 O13 P2 c1cc(c[n+]....
13 6FLG ic50 = 30.3 nM GZB VAL LEU DQK GLU TYR GLY VAL n/a n/a
14 6ENX - BJW C48 H64 N10 O19 P2 S CC(C)NC(=O....
15 6EO0 - BVT C47 H63 N11 O19 P2 S CC(C)NC(=O....
16 4UTV Ki = 100 uM BEZ GLY VAL LEU LYS GLU TYR GLY VAL FSL n/a n/a
17 1S7G - APR C15 H23 N5 O14 P2 c1nc(c2c(n....
18 1YC2 - APR C15 H23 N5 O14 P2 c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: APR; Similar ligands found: 398
No: Ligand ECFP6 Tc MDL keys Tc
1 APR 1 1
2 AR6 1 1
3 A2D 0.898551 0.971831
4 BA3 0.847222 0.971831
5 B4P 0.835616 0.971831
6 AP5 0.835616 0.971831
7 M33 0.813333 0.958333
8 ADP 0.810811 0.971831
9 ADV 0.805195 0.958904
10 RBY 0.805195 0.958904
11 HEJ 0.802632 0.971831
12 ATP 0.802632 0.971831
13 AT4 0.8 0.932432
14 AN2 0.8 0.958333
15 5FA 0.792208 0.971831
16 AQP 0.792208 0.971831
17 AD9 0.782051 0.945205
18 AGS 0.782051 0.92
19 SAP 0.782051 0.92
20 ACP 0.779221 0.945205
21 A 0.753425 0.943662
22 AMP 0.753425 0.943662
23 3OD 0.747126 0.972222
24 PRX 0.746835 0.893333
25 9X8 0.744186 0.945946
26 OAD 0.744186 0.972222
27 CA0 0.74359 0.972222
28 ADX 0.74359 0.873418
29 ACQ 0.740741 0.945205
30 ANP 0.740741 0.945205
31 A22 0.738095 0.958333
32 50T 0.734177 0.931507
33 A2R 0.72619 0.985915
34 ABM 0.723684 0.917808
35 ATF 0.722892 0.932432
36 A1R 0.72093 0.907895
37 ADQ 0.72093 0.972222
38 A3R 0.72093 0.907895
39 6YZ 0.714286 0.945205
40 A12 0.705128 0.932432
41 AP2 0.705128 0.932432
42 SRA 0.697368 0.893333
43 5AL 0.690476 0.958333
44 APC 0.682927 0.932432
45 AU1 0.679012 0.945205
46 TAT 0.678571 0.932432
47 T99 0.678571 0.932432
48 SRP 0.674419 0.932432
49 BIS 0.67033 0.907895
50 25L 0.663043 0.958333
51 4AD 0.662921 0.945946
52 DLL 0.655556 0.958333
53 00A 0.655556 0.907895
54 ADP PO3 0.654762 0.943662
55 8QN 0.651685 0.958333
56 5SV 0.651685 0.848101
57 OOB 0.651685 0.958333
58 25A 0.651685 0.944444
59 DQV 0.649485 0.958333
60 PAJ 0.644444 0.909091
61 AMO 0.644444 0.958904
62 MAP 0.640449 0.92
63 OMR 0.64 0.875
64 AFH 0.639175 0.909091
65 AHX 0.637363 0.896104
66 FYA 0.634409 0.905405
67 3UK 0.630435 0.945205
68 NAX 0.63 0.873418
69 G3A 0.628866 0.896104
70 SON 0.626506 0.932432
71 ALF ADP 0.625 0.87013
72 ADP ALF 0.625 0.87013
73 B5V 0.623656 0.932432
74 PR8 0.623656 0.873418
75 WAQ 0.623656 0.907895
76 LAD 0.623656 0.884615
77 G5P 0.622449 0.896104
78 GAP 0.62069 0.918919
79 LMS 0.620253 0.82716
80 48N 0.62 0.921053
81 ADP VO4 0.617977 0.931507
82 VO4 ADP 0.617977 0.931507
83 AP0 0.617647 0.896104
84 ME8 0.617021 0.8625
85 TXA 0.617021 0.958904
86 PTJ 0.617021 0.896104
87 1ZZ 0.617021 0.8625
88 NB8 0.617021 0.921053
89 GTA 0.616162 0.8625
90 FA5 0.614583 0.932432
91 TXD 0.613861 0.907895
92 NAI 0.613861 0.907895
93 6V0 0.613861 0.896104
94 DND 0.613861 0.958904
95 NXX 0.613861 0.958904
96 TXE 0.607843 0.907895
97 DAL AMP 0.604396 0.931507
98 9SN 0.604167 0.896104
99 UP5 0.598039 0.92
100 YAP 0.597938 0.92
101 B5Y 0.597938 0.92
102 B5M 0.597938 0.92
103 9ZD 0.597826 0.907895
104 9ZA 0.597826 0.907895
105 XAH 0.591837 0.839506
106 RAB 0.589041 0.84507
107 ADN 0.589041 0.84507
108 XYA 0.589041 0.84507
109 2A5 0.586207 0.893333
110 4UV 0.585859 0.92
111 AOC 0.585366 0.821918
112 ADJ 0.584906 0.875
113 7D4 0.581395 0.88
114 ITT 0.581395 0.916667
115 A4P 0.580952 0.821429
116 ATR 0.579545 0.943662
117 PAP 0.579545 0.957747
118 CNA 0.579439 0.932432
119 ADP BMA 0.578947 0.945205
120 5AS 0.576471 0.77907
121 4UU 0.574257 0.92
122 GA7 0.574257 0.906667
123 F2R 0.574074 0.864198
124 5N5 0.573333 0.819444
125 7D3 0.571429 0.88
126 4TC 0.571429 0.896104
127 139 0.570093 0.873418
128 T5A 0.570093 0.841463
129 COD 0.568807 0.811765
130 JB6 0.56701 0.883117
131 A4D 0.565789 0.819444
132 5CD 0.565789 0.805556
133 EP4 0.564103 0.753247
134 LAQ 0.563107 0.8625
135 NA7 0.5625 0.932432
136 TYM 0.561905 0.932432
137 80F 0.558559 0.864198
138 YLP 0.557692 0.841463
139 A A 0.556701 0.917808
140 G5A 0.555556 0.77907
141 HFD 0.555556 0.92
142 4UW 0.552381 0.884615
143 ATP A A A 0.55 0.930556
144 AVV 0.547368 0.896104
145 A3P 0.546512 0.943662
146 MYR AMP 0.545455 0.839506
147 7D5 0.54321 0.853333
148 G1R 0.542553 0.907895
149 YLC 0.542056 0.8625
150 UPA 0.542056 0.907895
151 YLB 0.542056 0.841463
152 NAD 0.540541 0.931507
153 TYR AMP 0.539216 0.894737
154 AMP DBH 0.539216 0.918919
155 TAD 0.538462 0.884615
156 DTA 0.5375 0.786667
157 M2T 0.5375 0.734177
158 3DH 0.536585 0.773333
159 AYB 0.536364 0.831325
160 EAD 0.533898 0.873418
161 AHZ 0.533333 0.839506
162 FB0 0.532787 0.784091
163 IOT 0.53211 0.831325
164 A3D 0.530973 0.918919
165 MTA 0.530864 0.773333
166 3AM 0.53012 0.902778
167 ARG AMP 0.528846 0.829268
168 AR6 AR6 0.528846 0.944444
169 A2P 0.528736 0.929577
170 YLA 0.527273 0.841463
171 6AD 0.526882 0.884615
172 PPS 0.526882 0.85
173 BTX 0.526786 0.819277
174 NAE 0.525862 0.894737
175 BT5 0.522124 0.831325
176 A5A 0.521277 0.807229
177 TSB 0.520833 0.819277
178 6RE 0.517647 0.7375
179 P1H 0.516393 0.851852
180 3AT 0.516129 0.944444
181 SSA 0.515789 0.8
182 7MD 0.514286 0.886076
183 54H 0.510417 0.788235
184 52H 0.510417 0.77907
185 VMS 0.510417 0.788235
186 NSS 0.510204 0.8
187 NAQ 0.508475 0.871795
188 ZAS 0.505882 0.766234
189 IMO 0.505747 0.902778
190 J7C 0.505747 0.746835
191 A3N 0.505747 0.786667
192 AV2 0.505263 0.891892
193 R5I 0.505263 0.918919
194 R7I 0.505263 0.918919
195 53H 0.505155 0.77907
196 5CA 0.505155 0.8
197 8X1 0.505155 0.752809
198 ARU 0.50505 0.8375
199 NVA LMS 0.50505 0.752809
200 9K8 0.504951 0.733333
201 AF3 ADP 3PG 0.504587 0.860759
202 YLY 0.504274 0.831325
203 ZID 0.504202 0.918919
204 S4M 0.5 0.666667
205 V3L 0.5 0.971831
206 FDA 0.5 0.811765
207 LEU LMS 0.5 0.752809
208 DTP 0.5 0.88
209 LPA AMP 0.5 0.839506
210 2AM 0.5 0.916667
211 FNK 0.496183 0.784091
212 6FA 0.496063 0.841463
213 DZD 0.495652 0.884615
214 P5A 0.49505 0.744444
215 DSZ 0.494949 0.821429
216 LSS 0.494949 0.761364
217 MAO 0.494382 0.759036
218 DSH 0.494253 0.725
219 M24 0.491525 0.873418
220 NJP 0.491228 0.92
221 5X8 0.48913 0.786667
222 DAT 0.48913 0.88
223 SFD 0.488372 0.734043
224 FAS 0.488372 0.851852
225 FAD 0.488372 0.851852
226 NAJ PZO 0.487179 0.848101
227 0WD 0.486957 0.896104
228 NPW 0.486726 0.8625
229 7MC 0.486486 0.864198
230 7DT 0.483871 0.957747
231 7DD 0.483516 0.957747
232 GJV 0.483146 0.728395
233 OVE 0.482759 0.88
234 5AD 0.480519 0.746479
235 GSU 0.480392 0.8
236 KAA 0.480392 0.752809
237 NDE 0.48 0.906667
238 N0B 0.479339 0.841463
239 A5D 0.478723 0.786667
240 ODP 0.478261 0.884615
241 RGT 0.47619 0.958904
242 XNP 0.474138 0.85
243 4TA 0.474138 0.807229
244 AMP NAD 0.474138 0.931507
245 62F 0.473684 0.8625
246 NDP 0.473684 0.896104
247 SFG 0.473118 0.773333
248 NDC 0.472441 0.871795
249 YSA 0.471698 0.77907
250 NAJ PYZ 0.471074 0.807229
251 ENP 0.470588 0.918919
252 FAY 0.470149 0.8625
253 TXP 0.469565 0.896104
254 NZQ 0.469565 0.884615
255 DDS 0.46875 0.853333
256 A7D 0.467391 0.776316
257 RFL 0.466667 0.821429
258 ENQ 0.466019 0.943662
259 AAT 0.463918 0.707317
260 SA8 0.463158 0.728395
261 7C5 0.462963 0.818182
262 MHZ 0.462366 0.697674
263 8PZ 0.462264 0.8
264 71V 0.461538 0.883117
265 G A A A 0.461538 0.848101
266 F2N 0.460993 0.793103
267 NEC 0.460674 0.746667
268 A3G 0.460674 0.8
269 GGZ 0.46 0.825
270 6C6 0.458333 0.857143
271 SAH 0.458333 0.766234
272 SAI 0.458333 0.75641
273 P5F 0.457143 0.823529
274 Y3J 0.45679 0.726027
275 A A A 0.456311 0.905405
276 PO4 PO4 A A A A PO4 0.456311 0.902778
277 7D7 0.455696 0.743243
278 SMM 0.454545 0.705882
279 V1N 0.453704 0.944444
280 6IA 0.453608 0.814815
281 SAM 0.453608 0.710843
282 WSA 0.451327 0.788235
283 U A 0.45 0.883117
284 A G 0.449153 0.858974
285 EEM 0.44898 0.710843
286 PGS 0.446809 0.858974
287 ETB 0.446281 0.811765
288 DCA 0.446281 0.802326
289 U A G G 0.445378 0.858974
290 2SA 0.444444 0.932432
291 D5M 0.444444 0.853333
292 DA 0.444444 0.853333
293 GP3 0.443299 0.896104
294 9JJ 0.442857 0.8625
295 128 0.442478 0.776471
296 4YB 0.441441 0.781609
297 GEK 0.441176 0.759494
298 Z5A 0.44 0.77907
299 30N 0.44 0.734043
300 S7M 0.44 0.710843
301 AAM 0.43956 0.943662
302 0T1 0.439024 0.802326
303 COA 0.439024 0.802326
304 12D 0.4375 0.785714
305 FA9 0.4375 0.841463
306 C2R 0.436782 0.90411
307 AMZ 0.436782 0.890411
308 A3S 0.43617 0.810811
309 N6P 0.432692 0.888889
310 PUA 0.430894 0.860759
311 COS 0.428571 0.784091
312 TAP 0.428571 0.883117
313 AMX 0.428571 0.811765
314 1DG 0.428571 0.896104
315 CAO 0.428571 0.775281
316 AIR 0.428571 0.875
317 A6D 0.428571 0.722892
318 DG1 0.428571 0.896104
319 6K6 0.427184 0.90411
320 A3T 0.427083 0.821918
321 NIA 0.426966 0.8
322 649 0.426087 0.744444
323 GTP 0.425743 0.894737
324 SCO 0.425197 0.823529
325 CMX 0.425197 0.823529
326 G2R 0.424528 0.860759
327 GDP 0.424242 0.894737
328 7RA 0.423913 0.930556
329 OXK 0.423077 0.804598
330 0UM 0.423077 0.719512
331 8Q2 0.422414 0.772727
332 FCX 0.421875 0.795455
333 FAM 0.421875 0.784091
334 ACO 0.421875 0.775281
335 GCP 0.421569 0.871795
336 NAP 0.420635 0.918919
337 SXZ 0.420561 0.731707
338 GNH 0.42 0.883117
339 62X 0.419048 0.686047
340 A U 0.418803 0.87013
341 APU 0.418803 0.87013
342 HAX 0.418605 0.784091
343 NVA 2AD 0.418367 0.759494
344 GDC 0.418182 0.884615
345 GKE 0.418182 0.884615
346 GDD 0.418182 0.884615
347 101 0.417582 0.853333
348 GSP 0.417476 0.85
349 3AD 0.416667 0.805556
350 2MC 0.416667 0.75
351 HDV 0.415842 0.868421
352 FYN 0.415385 0.802326
353 3KK 0.415385 0.784091
354 G2Q 0.415094 0.860759
355 K15 0.415094 0.702381
356 NA0 0.414062 0.906667
357 7L1 0.414062 0.775281
358 IVC 0.413534 0.793103
359 S8M 0.413462 0.759494
360 NHD 0.413223 0.905405
361 7RP 0.413043 0.901408
362 MCD 0.412214 0.804598
363 SOP 0.412214 0.784091
364 CA6 0.412214 0.71134
365 COK 0.412214 0.784091
366 1VU 0.409091 0.775281
367 CO6 0.409091 0.784091
368 NMX 0.409091 0.741935
369 CMC 0.409091 0.804598
370 AS 0.408602 0.810127
371 QQY 0.406593 0.815789
372 ACK 0.406593 0.861111
373 6YU 0.40625 0.734043
374 CAJ 0.406015 0.804598
375 SCD 0.406015 0.823529
376 EO7 0.404255 0.788235
377 8BR 0.404255 0.881579
378 GNP 0.403846 0.871795
379 9GM 0.403846 0.871795
380 APX 0.40367 0.907895
381 KB1 0.40367 0.719512
382 TM1 0.40367 0.77381
383 SLU 0.403226 0.770115
384 BCO 0.402985 0.784091
385 MLC 0.402985 0.804598
386 3HC 0.402985 0.793103
387 1HE 0.402985 0.766667
388 A1S 0.402985 0.784091
389 1CZ 0.402878 0.795455
390 CC5 0.402439 0.816901
391 NMN AMP PO4 0.401639 0.87013
392 FAQ 0.40146 0.784091
393 COO 0.4 0.784091
394 YE1 0.4 0.793103
395 MCA 0.4 0.795455
396 CAA 0.4 0.793103
397 2BA 0.4 0.915493
398 CMP 0.4 0.901408
Ligand no: 2; Ligand: NAD; Similar ligands found: 230
No: Ligand ECFP6 Tc MDL keys Tc
1 A3D 0.872727 0.986111
2 NHD 0.821429 0.972222
3 NAP 0.811966 0.986111
4 NFD 0.791304 0.946667
5 NXX 0.765766 0.972603
6 DND 0.765766 0.972603
7 AMP NAD 0.74359 0.972222
8 ZID 0.737705 0.986111
9 NAQ 0.729508 0.934211
10 NAE 0.721311 0.959459
11 NA0 0.712 0.972603
12 TAP 0.704 0.921053
13 NDE 0.689922 0.972603
14 NAJ 0.683333 0.972222
15 NDC 0.679389 0.934211
16 NDO 0.674603 0.958904
17 N01 0.656 0.972222
18 CNA 0.642276 0.972603
19 NBP 0.621212 0.922078
20 8ID 0.609756 0.922078
21 A2D 0.576923 0.958333
22 ADP 0.575472 0.931507
23 NGD 0.574803 0.922078
24 BA3 0.566038 0.958333
25 M33 0.564815 0.918919
26 ADP PO3 0.563636 0.957747
27 B4P 0.560748 0.958333
28 AP5 0.560748 0.958333
29 AN2 0.555556 0.918919
30 AT4 0.555556 0.894737
31 GAP 0.553571 0.932432
32 OOB 0.551724 0.972222
33 CA0 0.550459 0.932432
34 9JJ 0.546053 0.898734
35 HEJ 0.545455 0.931507
36 ACP 0.545455 0.906667
37 ATP 0.545455 0.931507
38 DQV 0.544 0.972222
39 ADP ALF 0.54386 0.883117
40 ALF ADP 0.54386 0.883117
41 DAL AMP 0.543103 0.945205
42 APR 0.540541 0.931507
43 AQP 0.540541 0.931507
44 AR6 0.540541 0.931507
45 5FA 0.540541 0.931507
46 ADP VO4 0.53913 0.945205
47 VO4 ADP 0.53913 0.945205
48 AD9 0.535714 0.906667
49 SAP 0.535714 0.883117
50 AGS 0.535714 0.883117
51 WAQ 0.533333 0.896104
52 ABM 0.53271 0.905405
53 DLL 0.529412 0.972222
54 00A 0.529412 0.921053
55 ACQ 0.526316 0.906667
56 NJP 0.526316 0.959459
57 ANP 0.526316 0.906667
58 OAD 0.525 0.932432
59 ADX 0.522523 0.839506
60 5AL 0.521739 0.945205
61 A1R 0.521008 0.871795
62 9SN 0.520325 0.909091
63 A 0.518868 0.930556
64 AMP 0.518868 0.930556
65 50T 0.517857 0.893333
66 ATF 0.517241 0.894737
67 1ZZ 0.516393 0.851852
68 3OD 0.516393 0.932432
69 SON 0.513514 0.92
70 PRX 0.513274 0.881579
71 6YZ 0.512821 0.906667
72 SRP 0.512821 0.92
73 9X8 0.512397 0.883117
74 ADP BMA 0.512397 0.932432
75 3UK 0.512397 0.958904
76 MYR AMP 0.512195 0.851852
77 NAJ PZO 0.510949 0.909091
78 NMN 0.509434 0.875
79 A3R 0.508333 0.871795
80 B5V 0.508197 0.945946
81 AMP DBH 0.507937 0.906667
82 A22 0.504202 0.945205
83 ATP A A A 0.504 0.971831
84 B5M 0.504 0.933333
85 FA5 0.504 0.945946
86 8QN 0.5 0.945205
87 NAX 0.496183 0.886076
88 TYR AMP 0.496063 0.933333
89 PR8 0.495935 0.8625
90 AMO 0.495868 0.92
91 ADQ 0.495868 0.932432
92 4AD 0.495868 0.933333
93 PAJ 0.495868 0.873418
94 A12 0.495495 0.894737
95 AP2 0.495495 0.894737
96 AHZ 0.492308 0.851852
97 YAP 0.492063 0.933333
98 FYA 0.491935 0.918919
99 AHX 0.491803 0.884615
100 4UU 0.488372 0.933333
101 5SV 0.487603 0.8375
102 TAT 0.487179 0.894737
103 T99 0.487179 0.894737
104 APC 0.486957 0.894737
105 SRA 0.486239 0.881579
106 6V0 0.484848 0.909091
107 NAI 0.484848 0.921053
108 GTA 0.484615 0.898734
109 A A 0.483871 0.958333
110 LAD 0.483871 0.873418
111 AU1 0.482456 0.906667
112 F2R 0.481752 0.831325
113 OMR 0.481203 0.841463
114 TXE 0.481203 0.921053
115 AF3 ADP 3PG 0.481203 0.873418
116 LAQ 0.480916 0.851852
117 G3A 0.48062 0.909091
118 B5Y 0.480315 0.933333
119 NB8 0.48 0.884615
120 TXA 0.48 0.92
121 BIS 0.48 0.871795
122 ME8 0.48 0.851852
123 PTJ 0.48 0.884615
124 139 0.477941 0.886076
125 LPA AMP 0.477273 0.851852
126 AFH 0.476923 0.873418
127 AR6 AR6 0.476923 0.958333
128 G5P 0.476923 0.909091
129 ARG AMP 0.476923 0.841463
130 25L 0.47619 0.945205
131 NAJ PYZ 0.475524 0.864198
132 25A 0.47541 0.958333
133 9ZA 0.47541 0.896104
134 9ZD 0.47541 0.896104
135 DZD 0.47482 0.897436
136 TXD 0.473684 0.921053
137 4UV 0.472868 0.933333
138 TYM 0.470149 0.945946
139 RBY 0.470085 0.894737
140 ADV 0.470085 0.894737
141 4TA 0.467626 0.864198
142 48N 0.466165 0.884615
143 XAH 0.465116 0.851852
144 4UW 0.462687 0.897436
145 M24 0.461538 0.886076
146 80F 0.460993 0.853659
147 IOT 0.459854 0.821429
148 T5A 0.456522 0.853659
149 EAD 0.455782 0.886076
150 MAP 0.455285 0.883117
151 GA7 0.454545 0.894737
152 BT5 0.453901 0.821429
153 A4P 0.452555 0.833333
154 UP5 0.451852 0.933333
155 PAP 0.445378 0.917808
156 4TC 0.445255 0.909091
157 AP0 0.445255 0.884615
158 YLP 0.444444 0.831325
159 P1H 0.443709 0.864198
160 AOC 0.442478 0.810811
161 Z5A 0.439189 0.833333
162 LMS 0.4375 0.817073
163 2A5 0.436975 0.857143
164 A G 0.43662 0.921053
165 G A A A 0.43662 0.909091
166 COD 0.43662 0.802326
167 ADJ 0.435714 0.841463
168 YLB 0.434783 0.831325
169 YLC 0.434783 0.851852
170 U A G G 0.433566 0.921053
171 ATR 0.433333 0.90411
172 7MD 0.432836 0.851852
173 8X1 0.432 0.764045
174 G5A 0.429752 0.790698
175 PO4 PO4 A A A A PO4 0.429688 0.943662
176 TAD 0.42963 0.873418
177 5AS 0.42735 0.770115
178 BTX 0.426573 0.831325
179 YLA 0.425532 0.831325
180 DSZ 0.425197 0.790698
181 NCN 0.424779 0.805556
182 UPA 0.42446 0.921053
183 8PZ 0.424242 0.811765
184 VMS 0.424 0.8
185 54H 0.424 0.8
186 9K8 0.423077 0.744444
187 N0B 0.422819 0.853659
188 6AD 0.422764 0.85
189 AYB 0.422535 0.821429
190 7D3 0.422414 0.844156
191 YLY 0.421769 0.821429
192 TSB 0.420635 0.809524
193 ODP 0.41958 0.922078
194 AV2 0.419355 0.855263
195 FB0 0.419355 0.775281
196 A5A 0.419355 0.819277
197 NNR 0.419048 0.739726
198 A A A 0.418605 0.918919
199 U A 0.417808 0.946667
200 649 0.417266 0.775281
201 NMN AMP PO4 0.416667 0.933333
202 SSA 0.416 0.790698
203 P5A 0.415385 0.755556
204 LSS 0.414062 0.772727
205 A2R 0.412698 0.918919
206 52H 0.412698 0.790698
207 JB6 0.412214 0.896104
208 5N5 0.411215 0.783784
209 YSA 0.410448 0.811765
210 53H 0.409449 0.790698
211 5CA 0.409449 0.790698
212 ITT 0.408333 0.878378
213 7D4 0.408333 0.844156
214 NA7 0.407692 0.894737
215 LEU LMS 0.407692 0.784091
216 5CD 0.407407 0.794521
217 0WD 0.406897 0.909091
218 A3P 0.40678 0.930556
219 HFD 0.406504 0.883117
220 AVV 0.40625 0.860759
221 RAB 0.40566 0.808219
222 XYA 0.40566 0.808219
223 ADN 0.40566 0.808219
224 FDA 0.405063 0.823529
225 GSU 0.40458 0.790698
226 7MC 0.404255 0.831325
227 NSS 0.403101 0.811765
228 6FA 0.402516 0.853659
229 PPS 0.4 0.817073
230 NVA LMS 0.4 0.784091
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1S7G; Ligand: NAD; Similar sites found with APoc: 182
This union binding pocket(no: 1) in the query (biounit: 1s7g.bio1) has 28 residues
No: Leader PDB Ligand Sequence Similarity
1 5O0Z 9GB None
2 5WHU SIA None
3 6BR7 BEF None
4 5KK4 44E None
5 5WHU SIA GAL GLC None
6 2BOS GLA GAL GLC None
7 2BOS GLA GAL GLC NBU None
8 4LZB URA 0.840336
9 5X62 SAH 1.18577
10 2HMT NAI 1.38889
11 2FKA BEF 1.55039
12 2BQP GLC 1.7094
13 2I7C AAT 1.97628
14 4YAC NAI 1.97628
15 3COB ADP 1.97628
16 2PT9 2MH 1.97628
17 1JQ3 AAT 1.97628
18 4BTV RB3 1.97628
19 5WP5 SAH 1.97628
20 2GND MAN MMA 1.98413
21 1Q8O MAN MMA 1.98413
22 2AUY NAG MAN MMA 1.98413
23 2PHR MAN MAN 1.98413
24 4D5G FAD 2.37154
25 4D5G TPP 2.37154
26 2BHZ MAL 2.37154
27 2XOC ADP 2.37154
28 5KVA SAM 2.37154
29 2O07 MTA 2.37154
30 2O07 SPD 2.37154
31 5MPT SAH 2.37154
32 3WCS MAN NAG GAL 2.37154
33 2W68 SIA GAL BGC 2.5641
34 5LOG SAH 2.57511
35 1XX6 ADP 2.6178
36 3DXY SAM 2.75229
37 3JWH SAH 2.76498
38 5YLF BGC 2.7668
39 1KYQ NAD 2.7668
40 4YDD MGD 2.7668
41 4YDD MD1 2.7668
42 3DUV KDO 2.7668
43 4KRG SAH 2.7668
44 2AXR ABL 2.7668
45 2AOT SAH 2.7668
46 4ITU NAI 2.7668
47 4E13 NAD 2.7668
48 4ZGR NGA GAL 2.7668
49 3G89 SAM 2.81124
50 5KXE 6Y2 2.88066
51 1UAY ADN 2.89256
52 2UYQ SAM 2.90323
53 5H6S HDH 3.16206
54 4X7Y SAH 3.16206
55 2ZWS PLM 3.16206
56 5XIO HFG 3.16206
57 3B8I OXL 3.16206
58 6CB2 OLC 3.16206
59 4TVD BGC 3.16206
60 4JNA FAD 3.16206
61 5O0J GLC 3.16206
62 5E1M SAH 3.3195
63 1ZQ9 SAM 3.55731
64 5HJM MTA 3.55731
65 2EG5 SAH 3.55731
66 1GOJ ADP 3.55731
67 4KIB SAH 3.55731
68 3GWZ SAH 3.55731
69 3GXO SAH 3.55731
70 3MQ2 SAH 3.66972
71 2HNK SAH 3.76569
72 2C31 ADP 3.95257
73 2C31 TZD 3.95257
74 5LQ8 GB 3.95257
75 4MOB ADP 3.95257
76 3GRU AMP 3.95257
77 1G2O IMH 3.95257
78 3K8D KDO 3.95257
79 1M1B SPV 3.95257
80 5LKC FUC GLA A2G 3.95257
81 2PAR TMP 3.9801
82 5N5D SAM 3.9823
83 3IP8 B85 4.03226
84 6DUB SAH 4.05405
85 2VDV SAM 4.06504
86 4KGD FAD 4.34783
87 4KGD TDP 4.34783
88 1QPR PHT 4.34783
89 3VSE SAH 4.34783
90 4XDA ADP 4.34783
91 1D4D SIN 4.34783
92 1F52 ADP 4.34783
93 2OBM ADP 4.34783
94 2Q28 ADP 4.74308
95 3VYW SAM 4.74308
96 4A59 AMP 4.74308
97 6C4A PYR 4.74308
98 1N4K I3P 4.74308
99 3O0F AMP 4.74308
100 3GU3 SAH 4.92958
101 1V5F TPP 5.13834
102 1V5F FAD 5.13834
103 1X87 NAD 5.13834
104 4NEC SAH 5.13834
105 4OE4 NAD 5.13834
106 2YP9 SIA CMO 5.13834
107 5A9A UTP 5.34979
108 3FGZ BEF 5.46875
109 3I9U DTU 5.5336
110 1LOB MMA 5.76923
111 5F8F SFG 5.92885
112 1T9D 1MM 6.32411
113 1T9D PYD 6.32411
114 1T9D P25 6.32411
115 3L9W AMP 6.32411
116 1T9D FAD 6.32411
117 4DMG SAM 6.32411
118 5WKC FAD 6.32411
119 2XYQ SAH 6.32411
120 2WSB NAD 6.69291
121 3BXO SAM 6.69456
122 6DEN FAD 6.71937
123 6DEN G8A 6.71937
124 6DEN TP9 6.71937
125 2VVG ADP 6.71937
126 3EYA FAD 6.71937
127 1SQL GUN 6.84932
128 3CBG SAH 6.89655
129 5TVM PUT 7.05882
130 1EFV FAD 7.11462
131 1EFV AMP 7.11462
132 1PJS NAD 7.11462
133 3FXU TSU 7.11462
134 4YSX E23 7.11462
135 4CQM NAP 7.11462
136 1LSS NAD 7.14286
137 2ZX2 RAM 7.17949
138 3EGI ADP 7.28155
139 2ZIF SAM 7.50988
140 1L3I SAH 7.8125
141 4Y9D NAI 7.90514
142 3DUW SAH 8.07175
143 3TD3 GLY 8.13008
144 6GI2 8SW 8.3004
145 2J9D AMP 8.40336
146 1P77 ATR 8.69565
147 4HA6 PXM 8.69565
148 1JG3 ADN 8.93617
149 4L2I FAD 9.48617
150 5A3B APR 9.88142
151 1RLZ NAD 9.88142
152 1YBH FAD 10.2767
153 1V59 NAD 10.2767
154 3T7S SAM 10.2767
155 4RF7 ARG 10.6719
156 4JZ8 CIT 11.0672
157 3RKR NAP 11.0672
158 5DNK SAH 11.4625
159 1U4L H1S 11.7647
160 1DJL NAP 12.0773
161 2DPM SAM 12.253
162 4DCM SAM 12.253
163 1JGS SAL 12.3188
164 1NU4 MLA 12.3711
165 1G8K MGD 12.782
166 1LNX URI 13.5802
167 1D4O NAP 13.587
168 1O97 FAD 13.6364
169 1O97 AMP 13.6364
170 2QX0 PH2 13.8365
171 3GCM 5GP 14.2292
172 5WSY 7UC 14.4509
173 1EJ0 SAM 15
174 1NBU PH2 15.126
175 2V3V MGD 15.415
176 3FJG 3PG 16.3347
177 1NM5 NAD 17.2414
178 1NM5 NAP 17.2414
179 4KFU ACP 17.9245
180 1PNO NAP 19.4444
181 2OOR TXP 20.1149
182 4I4S LAT 24.6575
Pocket No.: 2; Query (leader) PDB : 1S7G; Ligand: NAD; Similar sites found with APoc: 48
This union binding pocket(no: 2) in the query (biounit: 1s7g.bio1) has 28 residues
No: Leader PDB Ligand Sequence Similarity
1 2BOI MFU None
2 1W0O SIA 1.97628
3 1GPE FAD 1.97628
4 1U1J MET 2.37154
5 3ZV6 NAD 2.37154
6 3ZV6 4HB 2.37154
7 2XOC ADE 2.37154
8 2P3V SRT 2.37154
9 1Z03 OCH 2.37154
10 2EAE FUL 2.7668
11 6BND OPE 2.7668
12 4JLV ADP 2.7668
13 3LL5 IP8 2.81124
14 4LWP SAH 3.16206
15 2WME NAP 3.55731
16 5X7Q GLC GLC GLC GLC 3.95257
17 4DO1 ANN 3.95257
18 5W3Y ACO 4.34783
19 2BFR ADP 4.6875
20 4IF4 BEF 4.80769
21 3T0W DIW 4.87805
22 5ZRR 9J3 5.13834
23 1GTE FAD 5.92885
24 2GNK ATP 6.25
25 3EF0 ALF 6.32411
26 3PMA SCR 6.32411
27 1UWK URO 6.71937
28 1UWK NAD 6.71937
29 5FA5 MTA 7.50988
30 4FGC PQ0 7.87879
31 2FN8 RIP 7.90514
32 5NM7 GLY 8.3004
33 2C49 ADN 8.3004
34 1OFS SUC 8.33333
35 5LX9 OLB 8.69565
36 3CF6 SP1 8.98204
37 2XZ9 PYR 9.09091
38 1ZGS XMM 9.48617
39 6D5H FV7 10.1796
40 4DE3 DN8 10.2767
41 2GN2 C5P 10.2767
42 4U00 ADP 11.0656
43 1JA9 PYQ 11.8577
44 1ELI PYC 12.253
45 4WOH 4NP 13.253
46 1SC3 MLI 15.9091
47 5X2N ALA 17.3913
48 2OOR NAD 20.1149
Pocket No.: 3; Query (leader) PDB : 1S7G; Ligand: APR; Similar sites found with APoc: 291
This union binding pocket(no: 3) in the query (biounit: 1s7g.bio1) has 35 residues
No: Leader PDB Ligand Sequence Similarity
1 5KK4 44E None
2 4UP5 94W None
3 5O0Z 9GB None
4 2BOS GLA GAL GLC None
5 5WHU SIA None
6 2BOS GLA GAL GLC NBU None
7 6FX2 FUC C4W NAG BMA MAN NAG GAL None
8 5DUS APR None
9 5WHU SIA GAL GLC None
10 2BOI MFU None
11 4LZB URA 0.840336
12 1J71 THR ILE THR SER 1.18577
13 5X62 SAH 1.18577
14 2HMT NAI 1.38889
15 2PXX SAH 1.39535
16 1P1C SAH 1.50754
17 2FKA BEF 1.55039
18 5AVF TAU 1.58103
19 5WP5 SAH 1.97628
20 2PT9 S4M 1.97628
21 1XDS SAM 1.97628
22 2I7C AAT 1.97628
23 1BXG NAD 1.97628
24 4YUW 4JU 1.97628
25 5WP4 SAH 1.97628
26 2PT9 2MH 1.97628
27 1QZZ SAM 1.97628
28 1JQ3 AAT 1.97628
29 1ZEM NAD 1.97628
30 2II3 CAO 1.97628
31 2Q1S NAI 1.97628
32 4YUW S4M 1.97628
33 3GDH SAH 2.07469
34 5Z49 RUB 2.09205
35 4D5G FAD 2.37154
36 4D5G TPP 2.37154
37 5KVA SAM 2.37154
38 2BHZ MAL 2.37154
39 2HJR CIT 2.37154
40 3ITJ CIT 2.37154
41 2O07 SPD 2.37154
42 6EGU 43Y 2.37154
43 6BQ6 TER 2.37154
44 2O07 MTA 2.37154
45 1O9P MLA 2.37154
46 1RM0 D6P 2.37154
47 1RM0 NAI 2.37154
48 3W54 RNB 2.37154
49 4NBW NAD 2.37154
50 3R51 MMA 2.5
51 4Z7X 3CX 2.52101
52 5LOG SAH 2.57511
53 3DXY SAM 2.75229
54 3JWH SAH 2.76498
55 1KYQ NAD 2.7668
56 3DUV KDO 2.7668
57 2AOT SAH 2.7668
58 4YDD MGD 2.7668
59 4YDD MD1 2.7668
60 3FUU ADN 2.7668
61 1I2B NAD 2.7668
62 1I2B USQ 2.7668
63 1I2B UPG 2.7668
64 5TE1 7A2 2.7668
65 4WXJ GLU 2.7668
66 4KRG SAH 2.7668
67 2WPB ZZI 2.7668
68 3VC1 SAH 2.7668
69 5T8U LPA 2.7668
70 3SJ7 NDP 2.77778
71 2VT3 ATP 2.7907
72 3G89 SAM 2.81124
73 1UDH URA 2.86885
74 1UAY ADN 2.89256
75 3C3Y SAH 2.95359
76 2W58 ADP 2.9703
77 3I53 SAH 3.01205
78 4IWN GEK 3.05677
79 2ZWS PLM 3.16206
80 5H6S HDH 3.16206
81 2PV7 NAD 3.16206
82 4LWP SAH 3.16206
83 5JAQ NAI 3.16206
84 5JE8 NAD 3.16206
85 4X7Y SAH 3.16206
86 3KLL MAL 3.16206
87 3B8I OXL 3.16206
88 4JNA FAD 3.16206
89 5THQ NDP 3.16206
90 1E6W NAD 3.16206
91 2Q1W NAD 3.16206
92 1IM8 SAI 3.27869
93 5E1M SAH 3.3195
94 5NC1 NAG 3.37553
95 1T0S BML 3.48837
96 1R18 SAH 3.52423
97 1ZQ9 SAM 3.55731
98 5HJM MTA 3.55731
99 2EG5 SAH 3.55731
100 4KIB SAH 3.55731
101 1GY8 NAD 3.55731
102 3GWZ SAH 3.55731
103 4HXY NDP 3.55731
104 3GXO SAH 3.55731
105 2R09 4IP 3.55731
106 3RFV NAI 3.55731
107 1R6D NAD 3.55731
108 2FR1 NDP 3.55731
109 4II2 ATP 3.61446
110 2ZMF CMP 3.7037
111 2HNK SAH 3.76569
112 5U83 ZN8 3.77358
113 1WY7 SAH 3.86473
114 2BZG SAH 3.87931
115 5X7Q GLC GLC GLC GLC 3.95257
116 5X7Q GLC GLC GLC 3.95257
117 4XWT U5P 3.95257
118 2C31 ADP 3.95257
119 2C31 TZD 3.95257
120 3GRU AMP 3.95257
121 5LQ8 GB 3.95257
122 3K8D KDO 3.95257
123 3CL7 HYN 3.95257
124 3MCT SAH 3.95257
125 4ZZE GLC GLC GLC 3.95257
126 3PT9 SAH 3.95257
127 2PAR TMP 3.9801
128 5N5D SAM 3.9823
129 6DUB SAH 4.05405
130 2VDV SAM 4.06504
131 5TK8 7D5 4.12371
132 4CS9 AMP 4.2328
133 2BHW XAT 4.31034
134 3VSE SAH 4.34783
135 4KGD FAD 4.34783
136 4KGD TDP 4.34783
137 5W3Y ACO 4.34783
138 2CDU ADP 4.34783
139 3BP1 GUN 4.34783
140 4PTN PYR 4.34783
141 4L50 D8X 4.34783
142 2JK0 ASP 4.34783
143 1W8D NAP 4.34783
144 4TQK NAG 4.34783
145 1W6U NAP 4.34783
146 5ZI9 FLC 4.34783
147 3SSO SAH 4.34783
148 1XTP SAI 4.34783
149 1GXU 2HP 4.3956
150 3OFK SAH 4.62963
151 1FHX 4IP 4.65116
152 3UYW TAU 4.6729
153 2BFR ADP 4.6875
154 1YQC GLV 4.70588
155 3VYW SAM 4.74308
156 2Q28 ADP 4.74308
157 2EFJ SAH 4.74308
158 3ZDS HQ9 4.74308
159 4A59 AMP 4.74308
160 4IF4 BEF 4.80769
161 1TE2 PGA 4.86726
162 5ZW3 SAH 4.88889
163 3GU3 SAH 4.92958
164 1A8R GTP 4.97738
165 1HTW ADP 5.06329
166 5W10 CMP 5.12821
167 2WQ4 SFU 5.12821
168 1V5F FAD 5.13834
169 1V5F TPP 5.13834
170 1X87 NAD 5.13834
171 3LST SAH 5.13834
172 4NEC SAH 5.13834
173 1NJR XYL 5.13834
174 4NBU NAI 5.2
175 5A9A UTP 5.34979
176 4JCA CIT 5.38922
177 3FGZ BEF 5.46875
178 6EOM ALA LYS 5.5336
179 4YAG NAI 5.5336
180 6DNT NAD 5.5336
181 6F5W KG1 5.5336
182 3BGD SAH 5.76923
183 5YF1 SFG 5.92885
184 1A5Z NAD 5.92885
185 3L9W AMP 6.32411
186 1T9D 1MM 6.32411
187 1T9D P25 6.32411
188 4DMG SAM 6.32411
189 5WKC FAD 6.32411
190 1T9D FAD 6.32411
191 2XYQ SAH 6.32411
192 2R0D 4IP 6.32411
193 4NTX AMR 6.32411
194 4F2Q QUS 6.32411
195 1T9D PYD 6.32411
196 4CQK PIO 6.38298
197 6DEN FAD 6.71937
198 6DEN G8A 6.71937
199 6DEN TP9 6.71937
200 2RBK VN4 6.71937
201 1UWK URO 6.71937
202 1UWK NAD 6.71937
203 5WXU FLC 6.71937
204 3EYA FAD 6.71937
205 1R27 MGD 6.71937
206 1FQK ALF 6.80272
207 1SQL GUN 6.84932
208 3CBG SAH 6.89655
209 3DMH SAM 7.08661
210 1PJS NAD 7.11462
211 1EFV FAD 7.11462
212 1EFV AMP 7.11462
213 1BGV GLU 7.11462
214 4CQM NAP 7.11462
215 1LSS NAD 7.14286
216 3EGI ADP 7.28155
217 5XNC MTA 7.50988
218 5FA5 MTA 7.50988
219 3VSV XYS 7.50988
220 1F3L SAH 7.50988
221 1WVG APR 7.50988
222 2ZIF SAM 7.50988
223 1FP2 SAH 7.50988
224 1L3I SAH 7.8125
225 4FGC PQ0 7.87879
226 4Y9D NAI 7.90514
227 4XBA 5GP 8
228 3DUW SAH 8.07175
229 1VHZ APR 8.08081
230 5BTX CMP 8.21918
231 6CZ7 MGD 8.3004
232 3GXA MET 8.3004
233 2NXE SAM 8.3004
234 2H6T IVA VAL VAL STA ALA STA 8.3004
235 4RDH AMP 8.33333
236 3IR1 MET 8.57143
237 6C8R SAH 8.69565
238 1P77 ATR 8.69565
239 5DNC ASN 8.69565
240 4YMH SAH 8.75
241 1UQX MMA 8.84956
242 1JG3 ADN 8.93617
243 4L2I FAD 9.48617
244 5DX1 SFG 9.48617
245 1OC2 NAD 9.48617
246 1OC2 TDX 9.48617
247 5DX0 SFG 9.48617
248 5DXA SFG 9.48617
249 5DX8 SFG 9.48617
250 5DWQ SFG 9.48617
251 5A3B APR 9.88142
252 1RLZ NAD 9.88142
253 6H3O FAD 9.88142
254 2EJU SAH 9.88142
255 4KAX 4IP 9.93789
256 1V59 NAD 10.2767
257 3T7S SAM 10.2767
258 1YBH FAD 10.2767
259 2GN2 C5P 10.2767
260 3HQP FDP 10.2767
261 2F1K NAP 10.2767
262 1L7N ALF 10.4265
263 2YX1 SFG 10.6719
264 1U2Z SAH 10.6719
265 5DNK SAH 11.4625
266 5BW4 SAM 11.4625
267 1GZ6 NAI 11.4625
268 3ZOA ACR 11.4625
269 6F5Z SAH 11.4754
270 1DJL NAP 12.0773
271 2DPM SAM 12.253
272 4DCM SAM 12.253
273 4KRI SAH 12.253
274 1G8K MGD 12.782
275 5LW0 AR6 12.987
276 1D4O NAP 13.587
277 1O97 FAD 13.6364
278 1O97 AMP 13.6364
279 5WSY 7UC 14.4509
280 1EJ0 SAM 15
281 2V3V MGD 15.415
282 5MGZ SAH 16.5254
283 1NM5 NAP 17.2414
284 1NM5 NAD 17.2414
285 3GEG NAD 19.4332
286 1PNO NAP 19.4444
287 5L95 AMP 20
288 2OOR TXP 20.1149
289 5J6Y BGC 26.0638
290 5J6Y GLC 26.0638
291 1LVL NAD 28.4585
Pocket No.: 4; Query (leader) PDB : 1S7G; Ligand: NAD; Similar sites found with APoc: 134
This union binding pocket(no: 4) in the query (biounit: 1s7g.bio1) has 32 residues
No: Leader PDB Ligand Sequence Similarity
1 1FUT 2GP None
2 5DUS APR None
3 1P1C SAH 1.50754
4 5ME4 HP4 1.58103
5 4WS6 WBU 1.68067
6 1XDS SAM 1.97628
7 2PT9 S4M 1.97628
8 1ZEM NAD 1.97628
9 1BW9 NAD 1.97628
10 2Q1S NAI 1.97628
11 2II3 CAO 1.97628
12 1Q8P MAN MMA 1.98413
13 2PHW MAN MAN 1.98413
14 2PHF MAN MAN 1.98413
15 1Q8V MAN MAN 1.98413
16 2V57 PRL 2.10526
17 4UP4 GAL NAG 2.37154
18 3ITJ CIT 2.37154
19 1O9P MLA 2.37154
20 3GGO NAI 2.37154
21 5U8U FAD 2.37154
22 3GGO ENO 2.37154
23 6BQ6 TER 2.37154
24 1UY4 XYP XYP XYP XYP 2.75862
25 3FUU ADN 2.7668
26 1I2B UPG 2.7668
27 1I2B USQ 2.7668
28 1I2B NAD 2.7668
29 3PLN U5P 2.7668
30 2WPB ZZI 2.7668
31 4BWL MN9 2.7668
32 3VC1 SAH 2.7668
33 2VT3 ATP 2.7907
34 1UDH URA 2.86885
35 4K7O EKZ 2.97619
36 3I53 SAH 3.01205
37 4IWN GEK 3.05677
38 5JE8 NAD 3.16206
39 4N49 SAM 3.16206
40 2PV7 NAD 3.16206
41 5CK5 GDP 3.16206
42 4JEJ 1GP 3.27869
43 1T0S BML 3.48837
44 1R18 SAH 3.52423
45 2Z3U CRR 3.55731
46 2R09 4IP 3.55731
47 4II2 ATP 3.61446
48 1WY7 SAH 3.86473
49 2BZG SAH 3.87931
50 5X7Q GLC GLC GLC 3.95257
51 5HCT 61P 3.95257
52 3MCT SAH 3.95257
53 3PT9 SAH 3.95257
54 5V6F MAN BMA MAN 4.34783
55 5ZI9 FLC 4.34783
56 4AZW SAM 4.34783
57 2CDU ADP 4.34783
58 2JK0 ASP 4.34783
59 1GXU 2HP 4.3956
60 3OFK SAH 4.62963
61 2EFJ SAH 4.74308
62 3QPB URA 4.74308
63 2AWN ADP 4.74308
64 1TE2 PGA 4.86726
65 5ZW3 SAH 4.88889
66 4POO SAM 5
67 1HTW ADP 5.06329
68 1NJR XYL 5.13834
69 3LST SAH 5.13834
70 5G61 FNY 5.13834
71 2HQM FAD 5.13834
72 1RGE 2GP 5.20833
73 5E72 SAM 5.5336
74 1L1E SAH 5.5336
75 3BGD SAH 5.76923
76 5YF1 SFG 5.92885
77 1V6A TRE 5.92885
78 2WPF WPF 5.92885
79 5GMH RX8 5.92885
80 2WPF FAD 5.92885
81 5IL1 SAM 6.13208
82 5TSH ANP 6.32411
83 6HKE LMR 6.71937
84 1R27 MGD 6.71937
85 3KRO PPV 6.71937
86 2PZM NAD 6.71937
87 2PZM UDP 6.71937
88 1FQK ALF 6.80272
89 5TVF PUT 7.05882
90 2YVJ NAI 7.33945
91 2GUD MAN 7.37705
92 2GUC MAN 7.37705
93 5XNC MTA 7.50988
94 1NE7 AGP 8.3004
95 2NXE SAM 8.3004
96 1DMR PGD 8.3004
97 1GET FAD 8.3004
98 6CZ7 MGD 8.3004
99 1GET NAP 8.3004
100 4RDH AMP 8.33333
101 4RDI ATP 8.33333
102 5VN0 FAD 8.69565
103 5VN0 NAI 8.69565
104 4R8L ASP 9.48617
105 1OC2 NAD 9.48617
106 1OC2 TDX 9.48617
107 5UN9 NHT 9.48617
108 1V59 FAD 10.2767
109 1L7N ALF 10.4265
110 2YX1 SFG 10.6719
111 5BW4 SAM 11.4625
112 2RAB NAD 11.4625
113 2RAB FAD 11.4625
114 1GZ6 NAI 11.4625
115 6F5Z SAH 11.4754
116 1L5Y BEF 11.6129
117 4D79 ATP 11.8577
118 4KRI SAH 12.253
119 5LW0 AR6 12.987
120 4L9Z OXL 13.4387
121 5AHN IMP 13.834
122 6FC1 MGP 14.0625
123 5W3X ACO 15
124 3DGY 2GP 15.4639
125 5MGZ SAH 16.5254
126 4YMU ATP 16.8182
127 4ZGS NAD 16.996
128 5W97 CHD 17.8082
129 3GEG NAD 19.4332
130 5L95 AMP 20
131 5YRG BGC GLC 21.1268
132 5YRJ BGC GLC 21.1268