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Receptor
PDB id Resolution Class Description Source Keywords
1SC6 2.09 Å EC: 1.1.1.95 CRYSTAL STRUCTURE OF W139G D-3-PHOSPHOGLYCERATE DEHYDROGENASE COMPLEXED WITH NAD+ ESCHERICHIA COLI ALLOSTERIC REGULATION PHOSPHOGLYCERATE DEHYDROGENASE PGDH OXIDOREDUCTASE
Ref.: MULTICONFORMATIONAL STATES IN PHOSPHOGLYCERATE DEHYDROGENASE BIOCHEMISTRY V. 43 3450 2004
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
NAD A:2101;
B:2102;
C:2103;
D:2104;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
submit data
663.425 C21 H27 N7 O14 P2 c1cc(...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1SC6 2.09 Å EC: 1.1.1.95 CRYSTAL STRUCTURE OF W139G D-3-PHOSPHOGLYCERATE DEHYDROGENASE COMPLEXED WITH NAD+ ESCHERICHIA COLI ALLOSTERIC REGULATION PHOSPHOGLYCERATE DEHYDROGENASE PGDH OXIDOREDUCTASE
Ref.: MULTICONFORMATIONAL STATES IN PHOSPHOGLYCERATE DEHYDROGENASE BIOCHEMISTRY V. 43 3450 2004
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 5 families.
1 2P9C - SER C3 H7 N O3 C([C@@H](C....
2 1SC6 - NAD C21 H27 N7 O14 P2 c1cc(c[n+]....
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 2P9C - SER C3 H7 N O3 C([C@@H](C....
2 1SC6 - NAD C21 H27 N7 O14 P2 c1cc(c[n+]....
50% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 2P9C - SER C3 H7 N O3 C([C@@H](C....
2 1SC6 - NAD C21 H27 N7 O14 P2 c1cc(c[n+]....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: NAD; Similar ligands found: 230
No: Ligand ECFP6 Tc MDL keys Tc
1 A3D 0.872727 0.986111
2 NHD 0.821429 0.972222
3 NAP 0.811966 0.986111
4 NFD 0.791304 0.946667
5 NXX 0.765766 0.972603
6 DND 0.765766 0.972603
7 AMP NAD 0.74359 0.972222
8 ZID 0.737705 0.986111
9 NAQ 0.729508 0.934211
10 NAE 0.721311 0.959459
11 NA0 0.712 0.972603
12 TAP 0.704 0.921053
13 NDE 0.689922 0.972603
14 NAJ 0.683333 0.972222
15 NDC 0.679389 0.934211
16 NDO 0.674603 0.958904
17 N01 0.656 0.972222
18 CNA 0.642276 0.972603
19 NBP 0.621212 0.922078
20 8ID 0.609756 0.922078
21 A2D 0.576923 0.958333
22 ADP 0.575472 0.931507
23 NGD 0.574803 0.922078
24 BA3 0.566038 0.958333
25 M33 0.564815 0.918919
26 ADP PO3 0.563636 0.957747
27 B4P 0.560748 0.958333
28 AP5 0.560748 0.958333
29 AN2 0.555556 0.918919
30 AT4 0.555556 0.894737
31 GAP 0.553571 0.932432
32 OOB 0.551724 0.972222
33 CA0 0.550459 0.932432
34 9JJ 0.546053 0.898734
35 HEJ 0.545455 0.931507
36 ACP 0.545455 0.906667
37 ATP 0.545455 0.931507
38 DQV 0.544 0.972222
39 ADP ALF 0.54386 0.883117
40 ALF ADP 0.54386 0.883117
41 DAL AMP 0.543103 0.945205
42 APR 0.540541 0.931507
43 AQP 0.540541 0.931507
44 AR6 0.540541 0.931507
45 5FA 0.540541 0.931507
46 ADP VO4 0.53913 0.945205
47 VO4 ADP 0.53913 0.945205
48 AD9 0.535714 0.906667
49 SAP 0.535714 0.883117
50 AGS 0.535714 0.883117
51 WAQ 0.533333 0.896104
52 ABM 0.53271 0.905405
53 DLL 0.529412 0.972222
54 00A 0.529412 0.921053
55 ACQ 0.526316 0.906667
56 NJP 0.526316 0.959459
57 ANP 0.526316 0.906667
58 OAD 0.525 0.932432
59 ADX 0.522523 0.839506
60 5AL 0.521739 0.945205
61 A1R 0.521008 0.871795
62 9SN 0.520325 0.909091
63 A 0.518868 0.930556
64 AMP 0.518868 0.930556
65 50T 0.517857 0.893333
66 ATF 0.517241 0.894737
67 1ZZ 0.516393 0.851852
68 3OD 0.516393 0.932432
69 SON 0.513514 0.92
70 PRX 0.513274 0.881579
71 6YZ 0.512821 0.906667
72 SRP 0.512821 0.92
73 9X8 0.512397 0.883117
74 ADP BMA 0.512397 0.932432
75 3UK 0.512397 0.958904
76 MYR AMP 0.512195 0.851852
77 NAJ PZO 0.510949 0.909091
78 NMN 0.509434 0.875
79 A3R 0.508333 0.871795
80 B5V 0.508197 0.945946
81 AMP DBH 0.507937 0.906667
82 A22 0.504202 0.945205
83 ATP A A A 0.504 0.971831
84 B5M 0.504 0.933333
85 FA5 0.504 0.945946
86 8QN 0.5 0.945205
87 NAX 0.496183 0.886076
88 TYR AMP 0.496063 0.933333
89 PR8 0.495935 0.8625
90 AMO 0.495868 0.92
91 ADQ 0.495868 0.932432
92 4AD 0.495868 0.933333
93 PAJ 0.495868 0.873418
94 A12 0.495495 0.894737
95 AP2 0.495495 0.894737
96 AHZ 0.492308 0.851852
97 YAP 0.492063 0.933333
98 FYA 0.491935 0.918919
99 AHX 0.491803 0.884615
100 4UU 0.488372 0.933333
101 5SV 0.487603 0.8375
102 TAT 0.487179 0.894737
103 T99 0.487179 0.894737
104 APC 0.486957 0.894737
105 SRA 0.486239 0.881579
106 6V0 0.484848 0.909091
107 NAI 0.484848 0.921053
108 GTA 0.484615 0.898734
109 A A 0.483871 0.958333
110 LAD 0.483871 0.873418
111 AU1 0.482456 0.906667
112 F2R 0.481752 0.831325
113 OMR 0.481203 0.841463
114 TXE 0.481203 0.921053
115 AF3 ADP 3PG 0.481203 0.873418
116 LAQ 0.480916 0.851852
117 G3A 0.48062 0.909091
118 B5Y 0.480315 0.933333
119 NB8 0.48 0.884615
120 TXA 0.48 0.92
121 BIS 0.48 0.871795
122 ME8 0.48 0.851852
123 PTJ 0.48 0.884615
124 139 0.477941 0.886076
125 LPA AMP 0.477273 0.851852
126 AFH 0.476923 0.873418
127 AR6 AR6 0.476923 0.958333
128 G5P 0.476923 0.909091
129 ARG AMP 0.476923 0.841463
130 25L 0.47619 0.945205
131 NAJ PYZ 0.475524 0.864198
132 25A 0.47541 0.958333
133 9ZA 0.47541 0.896104
134 9ZD 0.47541 0.896104
135 DZD 0.47482 0.897436
136 TXD 0.473684 0.921053
137 4UV 0.472868 0.933333
138 TYM 0.470149 0.945946
139 RBY 0.470085 0.894737
140 ADV 0.470085 0.894737
141 4TA 0.467626 0.864198
142 48N 0.466165 0.884615
143 XAH 0.465116 0.851852
144 4UW 0.462687 0.897436
145 M24 0.461538 0.886076
146 80F 0.460993 0.853659
147 IOT 0.459854 0.821429
148 T5A 0.456522 0.853659
149 EAD 0.455782 0.886076
150 MAP 0.455285 0.883117
151 GA7 0.454545 0.894737
152 BT5 0.453901 0.821429
153 A4P 0.452555 0.833333
154 UP5 0.451852 0.933333
155 PAP 0.445378 0.917808
156 4TC 0.445255 0.909091
157 AP0 0.445255 0.884615
158 YLP 0.444444 0.831325
159 P1H 0.443709 0.864198
160 AOC 0.442478 0.810811
161 Z5A 0.439189 0.833333
162 LMS 0.4375 0.817073
163 2A5 0.436975 0.857143
164 A G 0.43662 0.921053
165 G A A A 0.43662 0.909091
166 COD 0.43662 0.802326
167 ADJ 0.435714 0.841463
168 YLB 0.434783 0.831325
169 YLC 0.434783 0.851852
170 U A G G 0.433566 0.921053
171 ATR 0.433333 0.90411
172 7MD 0.432836 0.851852
173 8X1 0.432 0.764045
174 G5A 0.429752 0.790698
175 PO4 PO4 A A A A PO4 0.429688 0.943662
176 TAD 0.42963 0.873418
177 5AS 0.42735 0.770115
178 BTX 0.426573 0.831325
179 YLA 0.425532 0.831325
180 DSZ 0.425197 0.790698
181 NCN 0.424779 0.805556
182 UPA 0.42446 0.921053
183 8PZ 0.424242 0.811765
184 VMS 0.424 0.8
185 54H 0.424 0.8
186 9K8 0.423077 0.744444
187 N0B 0.422819 0.853659
188 6AD 0.422764 0.85
189 AYB 0.422535 0.821429
190 7D3 0.422414 0.844156
191 YLY 0.421769 0.821429
192 TSB 0.420635 0.809524
193 ODP 0.41958 0.922078
194 AV2 0.419355 0.855263
195 FB0 0.419355 0.775281
196 A5A 0.419355 0.819277
197 NNR 0.419048 0.739726
198 A A A 0.418605 0.918919
199 U A 0.417808 0.946667
200 649 0.417266 0.775281
201 NMN AMP PO4 0.416667 0.933333
202 SSA 0.416 0.790698
203 P5A 0.415385 0.755556
204 LSS 0.414062 0.772727
205 A2R 0.412698 0.918919
206 52H 0.412698 0.790698
207 JB6 0.412214 0.896104
208 5N5 0.411215 0.783784
209 YSA 0.410448 0.811765
210 53H 0.409449 0.790698
211 5CA 0.409449 0.790698
212 ITT 0.408333 0.878378
213 7D4 0.408333 0.844156
214 NA7 0.407692 0.894737
215 LEU LMS 0.407692 0.784091
216 5CD 0.407407 0.794521
217 0WD 0.406897 0.909091
218 A3P 0.40678 0.930556
219 HFD 0.406504 0.883117
220 AVV 0.40625 0.860759
221 RAB 0.40566 0.808219
222 XYA 0.40566 0.808219
223 ADN 0.40566 0.808219
224 FDA 0.405063 0.823529
225 GSU 0.40458 0.790698
226 7MC 0.404255 0.831325
227 NSS 0.403101 0.811765
228 6FA 0.402516 0.853659
229 PPS 0.4 0.817073
230 NVA LMS 0.4 0.784091
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1SC6; Ligand: NAD; Similar sites found with APoc: 964
This union binding pocket(no: 1) in the query (biounit: 1sc6.bio1) has 35 residues
No: Leader PDB Ligand Sequence Similarity
1 2EWM NAD None
2 1XG5 NAP 0.716846
3 3LU1 NAD 0.824176
4 1KPG SAH 1.0453
5 1KPH SAH 1.0453
6 4ZCC FAD 1.19048
7 4ZCC NAI 1.19048
8 4WBD ADP 1.23762
9 2JB2 FAD 1.23762
10 2JB2 PHE 1.23762
11 1KOL NAD 1.25628
12 1KEV NDP 1.4245
13 1MXH NAP 1.44928
14 1LJ8 NAD 1.48515
15 1M2W NAD 1.48515
16 2IID PHE 1.48515
17 2IID FAD 1.48515
18 1H6C NDP 1.48515
19 1H6C SIN 1.48515
20 3NTD FAD 1.48515
21 1VJT NAD 1.48515
22 3QVP FAD 1.48515
23 5NMX NAP 1.48515
24 3NTA FAD 1.48515
25 1Q0H NDP 1.48515
26 1Q0H FOM 1.48515
27 5NMX FAD 1.48515
28 5AHO TLA 1.4881
29 1RYD NDP 1.55039
30 5K4W THR 1.55763
31 5K4W NAI 1.55763
32 4DCM SAM 1.6
33 2BD0 NAP 1.63934
34 1JG3 ADN 1.70213
35 1RM0 D6P 1.73267
36 1RM0 NAI 1.73267
37 3UCL NAP 1.73267
38 3UCL FAD 1.73267
39 3UCL CYH 1.73267
40 1E1M NAP 1.73267
41 1E1M FAD 1.73267
42 1DJN ADP 1.73267
43 2B9W FAD 1.73267
44 4D04 FAD 1.73267
45 4D04 NAP 1.73267
46 3NT6 FAD 1.73267
47 2XVE FAD 1.73267
48 2XVF FAD 1.73267
49 1O0S NAI 1.73267
50 3M6W SAM 1.73267
51 3GDN FAD 1.73267
52 4YNU LGC 1.73267
53 5WGR FAD 1.73267
54 4YNU FAD 1.73267
55 3GDN HBX 1.73267
56 5YU3 NAD 1.74419
57 5YU3 PRO 1.74419
58 1YKJ PHB 1.77665
59 1YKJ FAD 1.77665
60 4CNK FAD 1.79028
61 1N9G NAP 1.81347
62 6EL3 NAP 1.83727
63 5D4V SAH 1.86567
64 1P0F NAP 1.87668
65 3OA2 NAD 1.88679
66 5TC4 NAD 1.89873
67 1ZEM NAD 1.9084
68 1KEW NAD 1.93906
69 1KEW TYD 1.93906
70 3MB5 SAM 1.96078
71 1RSG FAD 1.9802
72 1YY5 FAD 1.9802
73 5ZYN FAD 1.9802
74 1OBB NAD 1.9802
75 4BJZ FAD 1.9802
76 4BJZ P3A 1.9802
77 5O2N FLC 1.9802
78 4TXI FAD 1.9802
79 4PIV NDP 1.9802
80 2BRY FAD 1.9802
81 1COY FAD 1.9802
82 2BO4 FLC 2.01511
83 4DMG SAM 2.03562
84 5A1T NAI 2.05279
85 5A1T OXM 2.05279
86 3KC1 2T6 2.07715
87 4RDI ATP 2.08333
88 4RDH AMP 2.08333
89 4NTC FAD 2.08955
90 5ZBR ANP 2.13333
91 5KVA SAM 2.15827
92 1BDB NAD 2.16606
93 4D79 ATP 2.17391
94 1OMO NAD 2.17391
95 3C1O NAP 2.18069
96 5BJX NAD 2.18579
97 5BJX UDP 2.18579
98 3CTY FAD 2.19436
99 1EZ4 NAD 2.20126
100 5ZW3 SAH 2.22222
101 3OND ADN 2.22772
102 3OND NAD 2.22772
103 1PJS NAD 2.22772
104 4EDF UPG 2.22772
105 5YB7 ORN 2.22772
106 1PS9 NAP 2.22772
107 5YB7 FAD 2.22772
108 3FWN ATR 2.22772
109 3ICT FAD 2.22772
110 1Q9I TEO 2.22772
111 1Q9I FAD 2.22772
112 1PS9 FAD 2.22772
113 3S5W NAP 2.22772
114 3ICR FAD 2.22772
115 3ICS FAD 2.22772
116 5HSA FAS 2.22772
117 3S5W FAD 2.22772
118 1QMG APX 2.22772
119 2DKH 3HB 2.22772
120 2DKH FAD 2.22772
121 5E4R NAP 2.22772
122 3ICS ADP 2.22772
123 3ICT ADP 2.22772
124 3CIF NAD 2.22841
125 3CIF G3H 2.22841
126 4ZRN UPG 2.24359
127 4ZRN NAD 2.24359
128 1X7D ORN 2.28571
129 1X7D NAD 2.28571
130 1DIG NAP 2.28758
131 1DIG L37 2.28758
132 6CI9 NAP 2.3166
133 1FK8 NAD 2.33463
134 3VZS NAP 2.33463
135 1ZH8 NAP 2.35294
136 5YEC ATP 2.35294
137 4FN4 NAD 2.3622
138 2D2I NAP 2.36842
139 4GLL NAD 2.37389
140 2VHW NAI 2.38727
141 4XB2 NDP 2.38806
142 4XB2 HSE 2.38806
143 6CEP OXM 2.39521
144 6CEP NAD 2.39521
145 1V6A TRE 2.40964
146 4RVU NDP 2.40964
147 1F8F NAD 2.42588
148 1L1E SAH 2.43902
149 5G4L NDP 2.44755
150 1GR0 NAD 2.45232
151 2ZJ1 NAD 2.47525
152 2ZJ1 ARJ 2.47525
153 5MBX SP5 2.47525
154 5MBX FAD 2.47525
155 5G3U FDA 2.47525
156 3AYI HCI 2.47525
157 3AYI FAD 2.47525
158 1YQZ FAD 2.47525
159 5G3U ITW 2.47525
160 3K7M FAD 2.47525
161 4M52 FAD 2.47525
162 1KNR FAD 2.47525
163 2A8X FAD 2.47525
164 4M52 M52 2.47525
165 1U8X NAD 2.47525
166 5ZBC FAD 2.47525
167 1REO FAD 2.47525
168 4MIG G3F 2.47525
169 2BKA NDP 2.47934
170 2PK3 A2R 2.49221
171 5J60 FAD 2.5
172 3AB1 FAD 2.5
173 1K3T BRZ 2.50696
174 3OZ2 FAD 2.51889
175 2X6T NAP 2.52101
176 5JY6 NAD 2.52809
177 1LDN NAD 2.53165
178 6ECU SAH 2.53165
179 4O0L NDP 2.54545
180 4UP3 NDP 2.54777
181 4UP3 FAD 2.54777
182 5O42 9JW 2.55474
183 5O42 BGC 2.55474
184 5O42 NAD 2.55474
185 1SB8 UD2 2.55682
186 1SB8 NAD 2.55682
187 4TSK NDP 2.57143
188 5UR0 NAD 2.5788
189 4D3F NAP 2.58065
190 1GUZ NAD 2.58065
191 2CUL FAD 2.58621
192 3HAD NAD 2.5974
193 4ITU 1HS 2.60223
194 4ITU NAI 2.60223
195 6DNT NAD 2.61628
196 4XDZ NDP 2.62391
197 2DTX BMA 2.65152
198 2Q1S NAI 2.65252
199 3B1J NAD 2.65487
200 3B20 NAD 2.65487
201 2EV9 NAP 2.6616
202 2EV9 SKM 2.6616
203 3ITJ FAD 2.66272
204 1RM4 NDP 2.67062
205 3RKR NAP 2.67176
206 2JHF NAD 2.6738
207 4BVA NDP 2.68657
208 4BVA T3 2.68657
209 4MDH NAD 2.69461
210 4KOA NDP 2.7027
211 1DSS NAD 2.7027
212 5MDH NAD 2.7027
213 1J0X NAD 2.71084
214 1HDG NAD 2.71084
215 1E5Q NDP 2.72277
216 1H82 GZZ 2.72277
217 1H82 FAD 2.72277
218 2C7G FAD 2.72277
219 5BVA FAD 2.72277
220 2C7G ODP 2.72277
221 4MOP 2H5 2.72277
222 4Y1B NAP 2.72277
223 2ZXI FAD 2.72277
224 5OC1 FAD 2.72277
225 1P31 EPU 2.72277
226 4K5S FAD 2.72277
227 5MLR NAP 2.72277
228 5MLR GRQ 2.72277
229 4K5S PM0 2.72277
230 6F97 FAD 2.72277
231 2GJP MAL 2.72277
232 5XWV NDP 2.72277
233 5XWV 8H6 2.72277
234 5GUD NDP 2.72277
235 2AOT SAH 2.73973
236 2Y6Q FAD 2.76382
237 2Y6Q I7T 2.76382
238 2Q46 NAP 2.7668
239 1WVG APR 2.78552
240 2VT3 ATP 2.7907
241 5O9F 9ON 2.84091
242 5O9F NAD 2.84091
243 5W3X ACO 2.84091
244 1YKF NAP 2.84091
245 1R37 NAD 2.88184
246 2B4Q NAP 2.89855
247 1GV0 NAD 2.90323
248 1EQ2 NAP 2.90323
249 5AYV KPL 2.91262
250 5AYV NAP 2.91262
251 1E3I CXF 2.92553
252 4R5M NAP 2.92553
253 4R5M 4NO 2.92553
254 1D1T NAD 2.94906
255 2CDU FAD 2.9703
256 5BUK FAD 2.9703
257 4OPC PGT 2.9703
258 4OPC FDA 2.9703
259 5JCA FAD 2.9703
260 5JCA NDP 2.9703
261 4HXY NDP 2.9703
262 5J7X FAD 2.9703
263 2WET FAD 2.9703
264 2CDU ADP 2.9703
265 3QJ4 FAD 2.9703
266 3FG2 FAD 2.9703
267 1DLJ NAI 2.98507
268 1DLJ UGA 2.98507
269 2RGJ FAD 2.98507
270 1Z82 NDP 2.98507
271 5DF1 58X 2.98913
272 5DF1 NAP 2.98913
273 1N1G BCP 3.00546
274 5NUE NAD 3.01205
275 5NUF NAD 3.01205
276 6A0S NDP 3.01205
277 6A0S HSE 3.01205
278 3CBG SAH 3.01724
279 5OJL TXP 3.02013
280 5Z75 NAD 3.0581
281 6H45 QEI 3.06122
282 5FJN BE2 3.07018
283 5FJN FAD 3.07018
284 5ZI9 FLC 3.07692
285 1NY5 ADP 3.10078
286 1F06 NDP 3.125
287 1F06 2NP 3.125
288 1OSS BEN 3.13901
289 4KQW NAP 3.14286
290 1NV8 MEQ 3.16901
291 1NV8 SAM 3.16901
292 3ZNN 4WL 3.17003
293 3ZNN FAD 3.17003
294 1XPJ TLA 3.1746
295 4D42 W0I 3.19149
296 4D42 NAP 3.19149
297 3DXY SAM 3.21101
298 1UP7 NAD 3.21782
299 1MO9 FAD 3.21782
300 1MO9 KPC 3.21782
301 2VVM FAD 3.21782
302 2VVL FAD 3.21782
303 4XQC NAD 3.21782
304 5GSN NAP 3.21782
305 5GSN FAD 3.21782
306 5BRT CH9 3.21782
307 5GSN MMZ 3.21782
308 5BRT FAD 3.21782
309 4YKG NAD 3.21782
310 4XQC 13D 3.21782
311 6F7L FAD 3.21782
312 4YKG FAD 3.21782
313 1Q19 SSC 3.21782
314 1Z45 NAD 3.21782
315 5KOD IAC 3.21782
316 3WLE NAD 3.22581
317 2EG5 SAH 3.22581
318 5W3K 9TY 3.23529
319 5W3K NDP 3.23529
320 4XDY NAI 3.25444
321 3MAG SAH 3.25733
322 4RPL 3UC 3.25815
323 4RPL FAD 3.25815
324 3WBF NAP 3.27869
325 3WBF API 3.27869
326 1RPN NDP 3.28358
327 4LIK CIT 3.31633
328 2GAG NAD 3.33333
329 2GAG FOA 3.33333
330 2GAG FAD 3.33333
331 2CVQ NDP 3.36391
332 3MCT SAH 3.367
333 3FPZ AHZ 3.37423
334 5GZ6 7C3 3.37423
335 5GZ6 NDP 3.37423
336 3RK1 ATP 3.37553
337 1YS4 NAP 3.38983
338 5GT9 NAP 3.42205
339 2PT9 S4M 3.42679
340 5FEU NAP 3.43643
341 2NVK NAP 3.46535
342 1NVT NAP 3.46535
343 4EMI NAD 3.46535
344 2IVD FAD 3.46535
345 4U8P FDA 3.46535
346 4U8P UDP 3.46535
347 1RYI FAD 3.46535
348 3IHG FAD 3.46535
349 4EMI FAD 3.46535
350 2FR1 NDP 3.46535
351 1RYI GOA 3.46535
352 2NVK FAD 3.46535
353 1ZQ9 SAM 3.46535
354 2HMT NAI 3.47222
355 3P13 RIP 3.47222
356 4XZ3 COA 3.47826
357 1LUA NAP 3.48432
358 3GGO ENO 3.50318
359 3GGO NAI 3.50318
360 5X20 NAD 3.52564
361 1PGP 6PG 3.52697
362 6AM8 TRP 3.53535
363 2GZ3 NAP 3.55191
364 2G5C NAD 3.55872
365 4B7X NAP 3.57143
366 5X68 FAD 3.58056
367 1C0I FAD 3.58127
368 1C0I BE2 3.58127
369 2F1K NAP 3.58423
370 3CMC NAD 3.59281
371 2RH4 EMO 3.61011
372 2GLX NDP 3.61446
373 4IDC 1XX 3.61446
374 4IDC NDP 3.61446
375 2HK9 NAP 3.63636
376 2PZM UDP 3.63636
377 2PZM NAD 3.63636
378 2HK9 ATR 3.63636
379 5KVS 6XR 3.63636
380 5KVS NAP 3.63636
381 1M0S CIT 3.65297
382 6BWL NAD 3.65854
383 3WV8 ATP 3.66972
384 3HB5 NAP 3.66972
385 3NYC IAR 3.67454
386 3NYC FAD 3.67454
387 5T9E NAP 3.69004
388 5T9F NAP 3.69004
389 5T9F TYR 3.69004
390 2PV7 NAD 3.69128
391 5N0J FAD 3.7037
392 2YVF FAD 3.71287
393 2YVF NAD 3.71287
394 2JHP SAH 3.71287
395 4RSL FAD 3.71287
396 2Z3Y F2N 3.71287
397 3G5S FAD 3.71287
398 2QRK AMP 3.71287
399 2GMH FAD 3.71287
400 1D4D FAD 3.71287
401 5TTJ FAD 3.71287
402 2E5V FAD 3.71287
403 3AXB FAD 3.71287
404 3AXB PRO 3.71287
405 2R4J 13P 3.71287
406 2R4J FAD 3.71287
407 2RGO FAD 3.71287
408 4OJP MAL 3.71287
409 5I39 FAD 3.71287
410 1Q1R FAD 3.71287
411 4J1Q NDP 3.71287
412 4TQG NDP 3.71517
413 1VL8 NAP 3.74532
414 4W6Z 8ID 3.7464
415 2B4R AES 3.76812
416 2B4R NAD 3.76812
417 5ODQ FAD 3.78007
418 1I36 NAP 3.78788
419 1R6N 434 3.79147
420 4YAG NAI 3.80623
421 5KKA 6V0 3.84615
422 2YY7 NAD 3.84615
423 4C2W ANP 3.84615
424 5H81 NAP 3.85604
425 5JIB OIA 3.85757
426 3AFN NAP 3.87597
427 5OOH NAP 3.8835
428 5OOH 9ZZ 3.8835
429 2I7C AAT 3.88693
430 5FFF NAP 3.89105
431 4NBW NAD 3.89105
432 5FFF 5XC 3.89105
433 2DM6 IMN 3.9039
434 2DM6 NAP 3.9039
435 1I9G SAM 3.92857
436 6C4N NAP 3.9604
437 1HYE NAP 3.9604
438 5JWC FAD 3.9604
439 5VN0 NAI 3.9604
440 5VN0 FAD 3.9604
441 4HA6 FAD 3.9604
442 6FHO FAD 3.9604
443 1UJ5 5RP 3.96476
444 3NGL NAP 3.98551
445 1U3U BNF 4.01069
446 1U3U NAD 4.01069
447 5Y77 FAD 4.01691
448 5U5G NAP 4.0678
449 2YYY NAP 4.08163
450 2ZL4 ALA ALA ALA ALA 4.08163
451 1I8T FAD 4.08719
452 1YQD NAP 4.09836
453 6BYF CIT 4.11765
454 2V6G NAP 4.12088
455 4USQ FAD 4.15512
456 5JDI NAP 4.16667
457 3JQA NAP 4.16667
458 4CM8 NAP 4.16667
459 4CMI NAP 4.16667
460 4CM4 NAP 4.16667
461 5JCJ NAP 4.16667
462 3BMO NAP 4.16667
463 3JQ8 NAP 4.16667
464 5JDC NAP 4.16667
465 3JQF NAP 4.16667
466 3BMQ NAP 4.16667
467 4CLR NAP 4.16667
468 3JQ9 NAP 4.16667
469 3JQG NAP 4.16667
470 5K6A NAP 4.16667
471 3JQ7 NAP 4.16667
472 4CLO NAP 4.16667
473 3BMN NAP 4.16667
474 4CME NAP 4.16667
475 3JQB NAP 4.16667
476 4CM9 NAP 4.16667
477 1V59 NAD 4.1841
478 1V59 FAD 4.1841
479 1FL2 FAD 4.19355
480 3OJO NAD 4.20792
481 5J5Z FAD 4.20792
482 2CDC XYP 4.20792
483 1JNR FAD 4.20792
484 3ULK NDP 4.20792
485 2CDC XYS 4.20792
486 1QO8 FAD 4.20792
487 3RNM FAD 4.20792
488 3ETG GLU 4.20792
489 3ETG GTP 4.20792
490 2HQM FAD 4.20792
491 2CDC NAP 4.20792
492 3C7A NAD 4.20792
493 2Q1W NAD 4.20792
494 2QZZ EMF 4.20792
495 2QZZ NAP 4.20792
496 3ETG NDP 4.20792
497 3RC1 NAP 4.20792
498 3RC1 TLO 4.20792
499 1PL6 NAD 4.21348
500 1PL6 572 4.21348
501 4RKX 3S9 4.21456
502 3LZW NAP 4.21687
503 3LZW FAD 4.21687
504 6GAS FAD 4.22961
505 1G0N NDP 4.24028
506 1G0N PHH 4.24028
507 1JAY NAP 4.24528
508 2RI1 GLP 4.25532
509 2DT5 NAD 4.2654
510 4YUW S4M 4.27632
511 4YUW 4JU 4.27632
512 1ZBQ NAD 4.28135
513 1ORR NAD 4.32277
514 5BSH PRO 4.33213
515 5MZI FAD 4.33839
516 5MZI FYK 4.33839
517 5O4J PJL 4.37956
518 5O4J SAH 4.37956
519 5O4J 9KH 4.37956
520 3ORF NAD 4.38247
521 3ABI NAD 4.38356
522 1P77 ATR 4.41176
523 2BOS GLA GAL GLC 4.41176
524 2BOS GLA GAL GLC NBU 4.41176
525 3G89 SAM 4.41767
526 4L8V NAP 4.45104
527 1CF2 NAP 4.45104
528 3GEG NAD 4.45344
529 1MUU NAD 4.45545
530 1MV8 NAD 4.45545
531 5M67 NAD 4.45545
532 5M67 ADE 4.45545
533 5M67 3D1 4.45545
534 6C4T NA7 4.45545
535 1VKO NAD 4.45545
536 4YAC NAI 4.45545
537 4DSG UDP 4.45545
538 4DSG FAD 4.45545
539 4REP FAD 4.45545
540 4A0S NAP 4.45545
541 4YT4 FE9 4.45545
542 3V1U NAD 4.45545
543 4DPL NAP 4.45682
544 2V7O DRN 4.46429
545 2WD7 NAP 4.47761
546 2VZ0 NAP 4.47761
547 2VZ0 D64 4.47761
548 5L0R UDP 4.48179
549 2XYQ SAH 4.48276
550 1C3V NDP 4.4898
551 1BXK NAD 4.50704
552 3D3W NAP 4.5082
553 6GNA FAD 4.51389
554 3H4V NAP 4.51389
555 5NII FAD 4.53074
556 6BQ6 TER 4.53172
557 3SSO SAH 4.53461
558 1CDO NAD 4.54545
559 3VYW SAM 4.54545
560 1B8U OAA 4.55927
561 1B8U NAD 4.55927
562 5XNC MTA 4.58221
563 4Y9D NAI 4.59016
564 4JBI NDP 4.59459
565 3TWO NDP 4.5977
566 2AE2 PTO 4.61538
567 2AE2 NAP 4.61538
568 1Y8Q ATP 4.62428
569 1XHC FAD 4.63215
570 2FKA BEF 4.65116
571 4JJF N2I 4.65116
572 4JJF FE9 4.65116
573 3KLJ FAD 4.67532
574 4KP7 NAP 4.68384
575 4KP7 1UQ 4.68384
576 4YRY FAD 4.70297
577 4YRY NAD 4.70297
578 3LAD FAD 4.70297
579 1GPE FAD 4.70297
580 3L9W AMP 4.70297
581 1LVL NAD 4.70297
582 1LVL FAD 4.70297
583 4D7E FAD 4.70297
584 3L9W GSH 4.70297
585 1X14 NAD 4.73815
586 3GRU AMP 4.74576
587 5LD5 NAD 4.7486
588 1DRV A3D 4.7619
589 3VSE SAH 4.77387
590 3HDY FAD 4.78589
591 3HDY FDA 4.78589
592 3HDY GDU 4.78589
593 4NBU NAI 4.8
594 3H5N ATP 4.81586
595 1VM6 NAD 4.82456
596 2I3G NAP 4.82955
597 3RFV NAI 4.86891
598 3RFV 15L 4.86891
599 1OC2 NAD 4.88506
600 1OC2 TDX 4.88506
601 2NU8 COA 4.89691
602 2J5V PCA 4.90463
603 4E13 NAD 4.947
604 1V8B NAD 4.9505
605 3T31 DCQ 4.9505
606 3T31 FAD 4.9505
607 4J36 FAD 4.9505
608 4J36 1HR 4.9505
609 4X9M FAD 4.9505
610 5EOW FAD 4.9505
611 6C4M NAP 4.9505
612 1GY8 NAD 4.9505
613 5UAO FAD 4.9505
614 3F8D FAD 4.95356
615 1LLU NAD 4.97076
616 4NTD FAD 5
617 3FZG SAM 5
618 4EA7 COA 5
619 4EA7 JB2 5
620 1LTH NAD 5.01567
621 4J4H 1J1 5.01931
622 4J4H NAI 5.01931
623 4JK3 NAD 5.01931
624 1O8B ABF 5.02283
625 3NJ4 NAD 5.05747
626 3NJ4 AFX 5.05747
627 3L4S NAD 5.05952
628 3L4S 3PG 5.05952
629 4YCA NDP 5.10204
630 1U1I NAD 5.10204
631 1KYQ NAD 5.10949
632 2NXE SAM 5.11811
633 4YSX FAD 5.12821
634 5K0A FAD 5.15152
635 1RV0 NDG 5.18293
636 5ZI2 ADP 5.19802
637 5ZI2 NAD 5.19802
638 1GZ4 ATP 5.19802
639 2IXB NAD 5.19802
640 5MQ6 NDP 5.19802
641 2VTD LKM 5.19802
642 2IXB A2G 5.19802
643 4Z24 FAD 5.19802
644 4XYM COA 5.21739
645 4G5H NAP 5.23416
646 4G5H UD7 5.23416
647 1GZ6 NAI 5.32915
648 1R6D NAD 5.34125
649 1R6D DAU 5.34125
650 2FK8 SAM 5.34591
651 3A4V NAD 5.36278
652 3A4V PYR 5.36278
653 5U5N NAD 5.37634
654 2BGM NAJ 5.39568
655 5Y8L HUI 5.42373
656 5Y8L NAD 5.42373
657 6GNC FAD 5.44218
658 6GAR FAD 5.44413
659 2IZ1 ATR 5.44554
660 6ER9 FAD 5.44554
661 6ER9 NAP 5.44554
662 5VKT NAP 5.44554
663 2AQJ FAD 5.44554
664 2AQJ TRP 5.44554
665 4EIP FAD 5.44554
666 3O9Z AKG 5.44872
667 3O9Z NAD 5.44872
668 3H8V ATP 5.47945
669 4OM8 NAD 5.50162
670 2YVJ NAI 5.50459
671 2YVJ FAD 5.50459
672 2DC1 NAD 5.50847
673 5YAP NAI 5.52632
674 5YAP 8S0 5.52632
675 1EBF NAD 5.58659
676 5UAV NDP 5.59006
677 5UAV TFB 5.59006
678 4RGA 3PV 5.59796
679 4RQU NAD 5.6
680 5A04 BGC 5.60472
681 5A04 NDP 5.60472
682 4EMJ FAD 5.60748
683 1LSS NAD 5.69307
684 5U8U FAD 5.69307
685 5JCM ISD 5.69307
686 5JCM NAD 5.69307
687 5JCM FAD 5.69307
688 6FP4 E1T 5.69307
689 1ZK7 FAD 5.69307
690 6FP4 FAD 5.69307
691 5TUK FAD 5.69307
692 4X1B MLI 5.69307
693 2AG8 NAP 5.70342
694 1XKQ NDP 5.71429
695 2Q0L NAP 5.78778
696 2Q0L FAD 5.78778
697 3EGI ADP 5.82524
698 3DAG FEG 5.86592
699 5THQ NDP 5.88235
700 1NPD NAD 5.90278
701 5L4L NAP 5.92105
702 1WDK NAD 5.94059
703 6F3M NAD 5.94059
704 5OCM NAP 5.94059
705 2GV8 NDP 5.94059
706 2GVC FAD 5.94059
707 2GV8 FAD 5.94059
708 1VQW FAD 5.94059
709 1XCL SAH 5.95745
710 5N2I NAP 6.03448
711 3SJU NDP 6.09319
712 3A06 FOM 6.11702
713 3A06 NDP 6.11702
714 3GF4 UPG 6.15385
715 3GF4 FAD 6.15385
716 5URY PAM 6.16438
717 5A9A UTP 6.17284
718 3O03 NAP 6.18557
719 1UWK URO 6.18812
720 1UWK NAD 6.18812
721 5ZZ6 NAD 6.25
722 5ZZ6 ADP 6.25
723 6F9Q NAD 6.25
724 2D5A COA 6.25
725 1NYT NAP 6.27306
726 5JE8 NAD 6.29139
727 6AA8 NAD 6.29139
728 5EZ7 FAD 6.37755
729 1FEC FAD 6.43564
730 1PN0 FAD 6.43564
731 4AP3 NAP 6.43564
732 4AP3 FAD 6.43564
733 1PN0 IPH 6.43564
734 3UOY FAD 6.43564
735 3UOY NAP 6.43564
736 5TUF TDC 6.43564
737 5TUF FAD 6.43564
738 4KWI 1TJ 6.46388
739 4KWI NAP 6.46388
740 1HYH NAD 6.47249
741 4MP8 MLI 6.48968
742 4MP8 NAD 6.48968
743 1AE1 NAP 6.59341
744 1O6Z NAD 6.60066
745 1TPY SAH 6.62021
746 2WPF WPF 6.68317
747 2WPF FAD 6.68317
748 4OOE FOM 6.68317
749 4OOE NDP 6.68317
750 5FI3 NAP 6.68317
751 4TM3 FAD 6.68317
752 6EGU 43Y 6.68317
753 3NKS FAD 6.68317
754 3WQQ IB3 6.68317
755 3WQQ NDP 6.68317
756 1VDC FAD 6.90691
757 1YJQ NAP 6.93069
758 2NPX NAD 6.93069
759 3CGD FAD 6.93069
760 3CGD NAD 6.93069
761 3CGD COA 6.93069
762 4GUS FAD 6.93069
763 4FWE FAD 6.93069
764 4GUT FAD 6.93069
765 4HSU FAD 6.93069
766 3WGT FAD 6.93069
767 3WGT QSC 6.93069
768 5NA1 FAD 6.93069
769 2NPX FAD 6.93069
770 1SOW NAD 7.0122
771 5OVK NDP 7.03125
772 1P1C SAH 7.03518
773 4JNA FAD 7.05882
774 3VPH OXM 7.09677
775 3VPH NAD 7.09677
776 3U4C NDP 7.11744
777 1T26 GBD 7.14286
778 1T26 NAI 7.14286
779 2CVZ NDP 7.17822
780 4IV9 FAD 7.17822
781 6F3N ADN 7.20339
782 6F3N NAD 7.20339
783 1A5Z NAD 7.21003
784 4B4U NAP 7.26073
785 5ERG SAM 7.31071
786 6A3J SOE 7.31707
787 6A3J NAI 7.31707
788 4II2 ATP 7.36196
789 3AD8 NAD 7.38916
790 3AD8 PYC 7.38916
791 3AD8 FAD 7.38916
792 1G8S MET 7.3913
793 2P3V SRT 7.42188
794 1WP4 NDP 7.42574
795 1GQ2 NAP 7.42574
796 2YG3 FAD 7.42574
797 2A92 NAI 7.47664
798 1NVM NAD 7.53623
799 5E5U MLT 7.53769
800 5Z2F NAP 7.54717
801 1TDF NAP 7.59494
802 1TDF FAD 7.59494
803 2QA1 FAD 7.6
804 2JL1 NAP 7.66551
805 3CGB FAD 7.67327
806 2ZWS PLM 7.67327
807 4URF NAD 7.67327
808 1XHL NDP 7.74411
809 4CQM NAP 7.78689
810 4USI AKG 7.79221
811 1IY8 NAD 7.86517
812 1BZL GCG 7.92079
813 1BZL FAD 7.92079
814 4BV6 FAD 7.92079
815 3X0V FAD 7.92079
816 2RAB NAD 7.92079
817 3GD4 FAD 7.92079
818 3GD4 NAD 7.92079
819 2RAB FAD 7.92079
820 1VI2 NAD 8
821 1UXG FUM 8.09062
822 1UXG NAD 8.09062
823 4ZGR NGA GAL 8.09717
824 2AHR NAP 8.10811
825 1WZ1 DNS 8.13008
826 5TWB FAD 8.13953
827 5TOW NAI 8.16832
828 5TOW ADN 8.16832
829 1X87 NAD 8.16832
830 2FZW NAD 8.31099
831 6AIN FAD 8.37321
832 3E1T FAD 8.41584
833 5TS5 FAD 8.41584
834 4JDR FAD 8.41584
835 5KMS NAD 8.41584
836 5KMS FAD 8.41584
837 3GMB FAD 8.41584
838 2GN4 UD1 8.43023
839 2GN4 NDP 8.43023
840 4PLT NAI 8.45921
841 4PLT OXM 8.45921
842 5Y1G AKB 8.53659
843 5Y1G NAD 8.53659
844 4PLG NAI 8.68263
845 4PLG OXM 8.68263
846 9LDT NAD 8.73494
847 9LDB NAD 8.73494
848 4ZVV GN0 8.73494
849 4ZVV NAD 8.73494
850 1PZG A3D 8.76133
851 4J56 FAD 8.77193
852 2HJR APR 8.84146
853 5EES NAP 8.90688
854 3K5I AIR 8.91089
855 3WMX NAD 8.93855
856 6C0B MLI 8.97436
857 5H2U 1N1 8.98876
858 3Q3C NAD 9.0301
859 2Q7V FAD 9.23077
860 1KYZ FER 9.31507
861 4CJX NAP 9.40439
862 5KOX FAD 9.40594
863 5KOX RFP 9.40594
864 1RV1 IMZ 9.41177
865 5X9D 80F 9.53947
866 1FWV SGA MAG FUC 9.70149
867 4U7W NDP 9.7619
868 2C29 NAP 9.79228
869 3GFB NAD 10
870 1EJ0 SAM 10
871 2DFV NAD 10.0865
872 1BXG NAD 10.1124
873 1BW9 NAD 10.1124
874 1C1X NAD 10.1408
875 1GTE FAD 10.1485
876 1E6E FAD 10.1562
877 1UDB NAD 10.355
878 1UDB UFG 10.355
879 1I2B NAD 10.396
880 1I2B USQ 10.396
881 1I2B UPG 10.396
882 5HXI FAD 10.396
883 5MIT NAP 10.3976
884 5MIT FAD 10.3976
885 5E9W SAH 10.5769
886 5E8J SAH 10.5769
887 1LDM NAD 10.6383
888 1GET NAP 10.6436
889 1GET FAD 10.6436
890 3SJ7 NDP 10.7143
891 5CAE SIN 10.8626
892 5CAE COA 10.8626
893 1W73 NAP 10.9272
894 1W8D NAP 10.9272
895 1H2B NAJ 11.1386
896 5L95 AMP 11.25
897 1W6U NAP 11.2583
898 1TB4 PEJ 11.3861
899 3Q9N COA 11.3924
900 5L53 NAP 11.4198
901 4GKV NAD 11.6071
902 1U7T TDT 11.8774
903 3LXD FAD 11.8812
904 4POO SAM 12
905 3OFK SAH 12.037
906 5XVH NAP 12.0915
907 4B63 ORN 12.1287
908 4B63 FAD 12.1287
909 4B63 NAP 12.1287
910 2HNK SAH 12.1339
911 2B5W NAP 12.3249
912 1VL0 NAI 12.3288
913 2F5Z FAD 12.5
914 1HDR NAD 12.7049
915 1F8G NAD 12.7604
916 4RYV ZEA 12.9032
917 1SAY PYR 13.0194
918 1RP0 AHZ 13.0282
919 1WPQ NAD 13.1805
920 2OOR NAD 13.2812
921 1L7E NAI 13.2812
922 1LK7 DER 13.5371
923 1NM5 NAD 13.8021
924 3SQP FAD 14.3564
925 3QFA FAD 14.8515
926 4MO2 FDA 14.9457
927 4MO2 FAD 14.9457
928 4Z0H NAD 15.2695
929 1CER NAD 15.4079
930 3V1Y NAD 15.4303
931 5A96 GTP 16.0643
932 3MMH SME 16.1677
933 3H9E NAD 16.185
934 1O94 ADP 16.5625
935 4RJD TFP 16.6667
936 1J5P NAD 16.996
937 5EIN NAP 17.1512
938 3JYN NDP 17.2308
939 2VYN NAD 18.429
940 1GAD NAD 18.4848
941 1RJW ETF 18.8791
942 3QV1 NAD 19.5122
943 1KJ8 GAR 19.9488
944 2VOH CIT 21.6561
945 1E3W NAD 24.1379
946 1E6W NAD 24.2308
947 2O4C NAD 28.4211
948 3B1F NAD 28.6207
949 4XYB NDP 30.4348
950 2NAD NAD 30.5344
951 2GSD NAD 32.5871
952 4ZGS NAD 33.1606
953 5Z20 NAI 33.6232
954 5DN9 NAD 34.3407
955 1HKU NAD 34.3575
956 1J49 NAD 34.8348
957 5Z21 NAI 35.4749
958 2GCG NDP 36.0606
959 3BAZ NAP 36.9369
960 2DBZ NAP 39.2216
961 5AOV NAP 40.4762
962 4E5N NAD 42.1212
963 3KB6 NAD 42.8144
964 6BII NAP 47.1471
Pocket No.: 2; Query (leader) PDB : 1SC6; Ligand: NAD; Similar sites found with APoc: 202
This union binding pocket(no: 2) in the query (biounit: 1sc6.bio1) has 25 residues
No: Leader PDB Ligand Sequence Similarity
1 4XUC 43G None
2 4XUC SAM None
3 3O26 NDP 0.96463
4 3DMH SAM 1.04987
5 1MJT NAD 1.44092
6 1MXH DHF 1.44928
7 4C3Y FAD 1.48515
8 3NDJ SAH 1.48515
9 3NDJ JHZ 1.48515
10 4C3Y ANB 1.48515
11 5T67 JHZ 1.48515
12 5T67