Receptor
PDB id Resolution Class Description Source Keywords
1SKQ 1.8 Å NON-ENZYME: TRANSCRIPT_TRANSLATE THE CRYSTAL STRUCTURE OF SULFOLOBUS SOLFATARICUS ELONGATION FACTOR 1-ALPHA IN COMPLEX WITH MAGNESIUM AND GDP SULFOLOBUS SOLFATARICUS ELONGATION FACTORS ARCHAEA PROTEIN SYNTHESIS TRANSLATION
Ref.: THE CRYSTAL STRUCTURE OF SULFOLOBUS SOLFATARICUS ELONGATION FACTOR 1ALPHA IN COMPLEX WITH MAGNESIUM AND GDP. BIOCHEMISTRY V. 43 6630 2004
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GDP A:500;
B:501;
Valid;
Valid;
none;
none;
submit data
443.201 C10 H15 N5 O11 P2 c1nc2...
MG A:502;
Part of Protein;
none;
submit data
24.305 Mg [Mg+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1SKQ 1.8 Å NON-ENZYME: TRANSCRIPT_TRANSLATE THE CRYSTAL STRUCTURE OF SULFOLOBUS SOLFATARICUS ELONGATION FACTOR 1-ALPHA IN COMPLEX WITH MAGNESIUM AND GDP SULFOLOBUS SOLFATARICUS ELONGATION FACTORS ARCHAEA PROTEIN SYNTHESIS TRANSLATION
Ref.: THE CRYSTAL STRUCTURE OF SULFOLOBUS SOLFATARICUS ELONGATION FACTOR 1ALPHA IN COMPLEX WITH MAGNESIUM AND GDP. BIOCHEMISTRY V. 43 6630 2004
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 257 families.
1 1SKQ - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
2 1JNY - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
70% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 222 families.
1 1SKQ - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
2 1JNY - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
3 3WYA - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
50% Homology Family (17)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 1D2E Kd = 1 uM GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
2 1DG1 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
3 2BVN - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
4 1EFC - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
5 4H9G - 14J C5 H3 Br O3 c1cc(oc1C(....
6 4LBZ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
7 4LC0 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
8 1EXM - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
9 2C78 - PUL C47 H66 O13 C[C@@H]1[C....
10 1EFT - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
11 4LBV - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
12 4LBW - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
13 1HA3 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
14 4J0Q - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
15 1SKQ - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
16 1JNY - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
17 3WYA - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GDP; Similar ligands found: 153
No: Ligand ECFP6 Tc MDL keys Tc
1 GDP 1 1
2 GTP 0.909091 1
3 GP3 0.881579 0.973684
4 GNH 0.858974 0.986667
5 GNP 0.839506 0.973684
6 G 0.828947 0.986486
7 5GP 0.828947 0.986486
8 G1R 0.82716 0.986667
9 GCP 0.82716 0.973684
10 GSP 0.817073 0.948718
11 GAV 0.797619 0.961039
12 GMV 0.792683 0.973684
13 G2P 0.77381 0.961039
14 G2R 0.770115 0.961039
15 GDP MG 0.759036 0.923077
16 GP2 0.756098 0.961039
17 GDP BEF 0.75 0.9
18 GDD 0.747253 0.961039
19 GKE 0.747253 0.961039
20 GDC 0.747253 0.961039
21 GPG 0.741573 0.961039
22 G3D 0.732558 0.986486
23 ALF 5GP 0.729412 0.888889
24 Y9Z 0.728261 0.902439
25 GTP MG 0.724138 0.923077
26 BEF GDP 0.724138 0.888889
27 G5P 0.723404 0.973684
28 GFB 0.72043 0.961039
29 GTG 0.72043 0.936709
30 GDR 0.72043 0.961039
31 G4P 0.715909 0.986486
32 GCP G 0.715909 0.935065
33 6CK 0.712766 0.936709
34 G3A 0.712766 0.973684
35 GDP ALF 0.7 0.888889
36 GDP AF3 0.7 0.888889
37 YGP 0.698925 0.901235
38 JB2 0.697917 0.961039
39 GKD 0.697917 0.961039
40 GDX 0.690722 0.973684
41 GPD 0.690722 0.925
42 GMP 0.684211 0.88
43 0O2 0.666667 0.986486
44 G G 0.659574 0.935065
45 JB3 0.656863 0.948718
46 NGD 0.650485 0.961039
47 GDP 7MG 0.636364 0.911392
48 DGI 0.636364 0.923077
49 U2G 0.634615 0.936709
50 GPX 0.634409 0.946667
51 IDP 0.632184 0.972973
52 2MD 0.632075 0.891566
53 CAG 0.62963 0.880952
54 CG2 0.622642 0.936709
55 FEG 0.619048 0.879518
56 MGD 0.614679 0.891566
57 ZGP 0.613208 0.869048
58 GH3 0.612903 0.973333
59 3GP 0.611765 0.946667
60 MD1 0.607143 0.891566
61 PGD 0.59292 0.925
62 DGT 0.591398 0.923077
63 BGO 0.588785 0.924051
64 TPG 0.582609 0.840909
65 DBG 0.582609 0.948718
66 2GP 0.574713 0.96
67 FE9 0.570175 0.776596
68 I2C FE2 CMO CMO 0.566372 0.808989
69 G A A A 0.553571 0.923077
70 MGP 0.553191 0.961039
71 U A G G 0.548673 0.935065
72 G4M 0.548387 0.880952
73 6G0 0.547368 0.961039
74 G1R G1R 0.542373 0.924051
75 P2G 0.527473 0.883117
76 PGD O 0.525 0.850575
77 ADP 0.522222 0.92
78 GGM 0.517544 0.901235
79 DG 0.516484 0.910256
80 DGP 0.516484 0.910256
81 P1G 0.516129 0.871795
82 G G U 0.509259 0.935065
83 G1G 0.508475 0.925
84 IMP 0.505495 0.959459
85 G C 0.504348 0.9
86 GPC 0.491525 0.879518
87 G7M 0.483871 0.948052
88 6AD 0.479592 0.841463
89 ATP 0.473684 0.92
90 G2Q 0.471154 0.961039
91 U G A 0.469697 0.888889
92 5FA 0.46875 0.92
93 AQP 0.46875 0.92
94 GTA 0.468468 0.936709
95 7DD 0.468085 0.906667
96 G G G RPC 0.466102 0.875
97 SGP 0.463158 0.82716
98 01G 0.462963 0.902439
99 B4P 0.457447 0.894737
100 AP5 0.457447 0.894737
101 A2D 0.456522 0.894737
102 G G G C 0.455285 0.9125
103 ACQ 0.454545 0.896104
104 5GP 5GP 0.454545 0.883117
105 ANP 0.454545 0.896104
106 A G C C 0.451613 0.911392
107 APC G U 0.45082 0.886076
108 G U34 0.449153 0.888889
109 DG DG 0.448598 0.865854
110 ITT 0.447917 0.868421
111 BA3 0.446809 0.894737
112 35G 0.444444 0.933333
113 C2E 0.444444 0.921053
114 PCG 0.444444 0.933333
115 MGO 0.441176 0.864198
116 AN2 0.4375 0.907895
117 G C C C 0.4375 0.924051
118 M33 0.43299 0.883117
119 UCG 0.429688 0.911392
120 A G U 0.42963 0.888889
121 ACP 0.428571 0.896104
122 MGQ 0.424528 0.935897
123 7DT 0.424242 0.906667
124 APR 0.424242 0.894737
125 AR6 0.424242 0.894737
126 93A 0.42268 0.833333
127 A4P 0.420168 0.869048
128 SAP 0.42 0.873418
129 AD9 0.42 0.896104
130 AGS 0.42 0.873418
131 G8D 0.42 0.875
132 CA0 0.418367 0.896104
133 ATF 0.417476 0.884615
134 AGO 0.414634 0.888889
135 NIA 0.413043 0.82716
136 MGV 0.412844 0.890244
137 TAT 0.411765 0.884615
138 A1R 0.411215 0.839506
139 ADQ 0.411215 0.871795
140 RGT 0.410714 0.909091
141 CGP 0.409836 0.86747
142 AMP 0.408602 0.893333
143 A 0.408602 0.893333
144 UP5 0.40678 0.873418
145 C2R 0.406593 0.906667
146 AMZ 0.406593 0.918919
147 JBT 0.405882 0.778947
148 A22 0.40566 0.907895
149 25L 0.405405 0.907895
150 ADX 0.40404 0.809524
151 8OD 0.401961 0.946667
152 4TC 0.4 0.851852
153 50T 0.4 0.883117
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1SKQ; Ligand: GDP; Similar sites found: 526
This union binding pocket(no: 1) in the query (biounit: 1skq.bio1) has 15 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 4HSE ADP 0.00003208 0.49118 1.25945
2 1AQU A3P 0.0015 0.4549 1.3468
3 5TSH ANP 0.00001639 0.53898 1.37931
4 5TSH ADP 0.0000366 0.49452 1.37931
5 2X77 GDP 0.000000003306 0.66714 1.5873
6 1OS1 ATP 0.0001328 0.52524 1.6092
7 1OS1 PYR 0.0001433 0.52524 1.6092
8 5VGR GDP 0.00004007 0.45542 1.62413
9 2Y65 ADP 0.0000002293 0.56582 1.64384
10 4P4T GDP 0.000000006037 0.58346 1.66667
11 2XTZ GSP 0.00000000006596 0.83908 1.69492
12 1P9B GDP 0.000009715 0.56247 1.83908
13 1YTM ATP 0.00001228 0.45557 1.83908
14 1CT9 GLN 0.009684 0.40625 1.83908
15 2ZE7 AMP 0.004855 0.44056 1.97628
16 2ZE7 DST 0.005207 0.44056 1.97628
17 1RRC ADP 0.000005982 0.50878 1.99336
18 2XT3 ADP 0.0000006799 0.54809 2.03488
19 1FNN ADP 0.0001986 0.42462 2.05656
20 5JCP GDP ALF 0.00000002284 0.57865 2.06897
21 1XKV ATP 0.0000298 0.53289 2.06897
22 4YS0 ADP 0.001757 0.4005 2.06897
23 4XFR CIT 0.01304 0.40525 2.10773
24 2PZ8 APC 0.01806 0.40689 2.11268
25 1XP8 AGS 0.00004449 0.51482 2.18579
26 5CK5 GDP 0.00000001542 0.67913 2.21519
27 1XMV ADP 0.00001965 0.53853 2.24719
28 4PPF FLC 0.000002352 0.59911 2.28571
29 1T5C ADP 0.000000191 0.54669 2.29226
30 2ZR9 DTP 0.00004258 0.50081 2.29226
31 5I34 GDP 0.000001686 0.54921 2.29885
32 2FSH ANP 0.002716 0.43 2.29885
33 5WRJ A3P 0.0005643 0.48613 2.31023
34 1K6M AGS 0.000111 0.51968 2.31481
35 3ITJ FAD 0.03881 0.41713 2.36686
36 3FKQ ATP 0.00003035 0.46489 2.41287
37 3COB ADP 0.0000003874 0.55719 2.43902
38 5J1J ANP 0.000006155 0.44591 2.45614
39 1JI0 ATP 0.00002997 0.53101 2.5
40 3T34 GDP 0.00000003579 0.51698 2.5
41 2RCN GDP 0.0000000001366 0.78205 2.51397
42 4PFO ADP 0.00007448 0.5325 2.52874
43 5HR5 ADP 0.00006002 0.52361 2.52874
44 2ZPA ADP 0.0001765 0.503 2.52874
45 4IHQ ADP 0.0001318 0.49243 2.52874
46 5MZN ADP 0.00102 0.45621 2.52874
47 5HR5 FLC 0.02663 0.41051 2.52874
48 5L3W GDP 0.000003247 0.57961 2.61438
49 1VHT BA3 0.000133 0.50135 2.75229
50 1G41 ADP 0.00006132 0.51768 2.75862
51 2VF7 ADP 0.0001514 0.49578 2.75862
52 4IOK XPO 0.0004258 0.4923 2.75862
53 4IOK ADP 0.0005416 0.4923 2.75862
54 2XAU ADP 0.0003364 0.48179 2.75862
55 1BG2 ADP 0.00000006188 0.56504 2.76923
56 1R0X ATP 0.0001498 0.48978 2.7972
57 2FNA ADP 0.00001602 0.43888 2.80112
58 1M7G AV2 0.000000923 0.59474 2.8436
59 1M7G ADX 0.000006959 0.59474 2.8436
60 1M7G ADP 0.00001432 0.57485 2.8436
61 3ZFD ANP 0.00001679 0.54498 2.849
62 4M7V NAP 0.01567 0.42256 2.85714
63 4GOX A3P 0.00006153 0.41921 2.8754
64 5HGZ ACO 0.01166 0.42122 2.88066
65 1JJV ATP 0.00001032 0.51986 2.91262
66 4LYA ATP 0.000004316 0.53057 2.98851
67 5XDR ADP 0.0004424 0.44609 2.98851
68 1QHG ATP 0.01138 0.40955 2.98851
69 3UIE ANP 0.00002309 0.53827 3
70 4B5P ACO 0.0261 0.40605 3
71 5FTB ANP 0.00009013 0.46179 3.00231
72 5FHD ADP ALF 0.000115 0.41929 3.00231
73 2OZE AGS 0.0003345 0.48927 3.02013
74 1G6O ADP 0.00004955 0.47104 3.0303
75 5HCN GCP 0.00000006574 0.61335 3.06513
76 4KOT CE3 0.03899 0.40792 3.08642
77 2NCD ADP 0.000002306 0.59362 3.09524
78 4V03 ADP 0.000003427 0.51766 3.11284
79 3GJ0 GDP 0.000000001349 0.70415 3.16742
80 4ITM ATP 0.02098 0.40819 3.1746
81 1M2O GNP 0.000000000895 0.78172 3.21839
82 1R6B ADP 0.00007965 0.50923 3.21839
83 1Z6T ADP 0.00007231 0.4424 3.21839
84 3RC3 ANP 0.003224 0.42646 3.21839
85 1KUV CA5 0.01444 0.42442 3.21839
86 3SXN COA 0.009871 0.42008 3.21839
87 3CV2 OXL 0.012 0.40699 3.21839
88 1IBR GNP 0.00000001463 0.50837 3.24074
89 4ZNL BEF ADP 0.00001579 0.50454 3.28467
90 1D2N ANP 0.0006501 0.47714 3.30882
91 2OFW ADX 0.0000374 0.56784 3.36538
92 1VG8 GNP 0.000000003412 0.75517 3.38164
93 1VG0 GDP 0.000000001156 0.75127 3.38164
94 1G3M PCQ 0.005114 0.45493 3.40136
95 5GVR LMR 0.00188 0.42447 3.4188
96 4P32 ADP 0.0001715 0.5081 3.44828
97 2WHX ADP 0.00002856 0.49723 3.44828
98 2JLR ANP 0.0002345 0.49203 3.44828
99 5GJC ATP 0.0001032 0.48338 3.44828
100 2W58 ADP 0.000005012 0.58907 3.46535
101 5H56 TYD 0.00007114 0.54089 3.58974
102 5H56 ADP 0.00007114 0.54089 3.58974
103 5M04 GDP 0.00000000007854 0.78801 3.61111
104 3MD0 GDP 0.00000000008998 0.78521 3.66197
105 3LRE ADP 0.0000003452 0.64913 3.66197
106 1JWY GDP 0.000000001859 0.74119 3.67816
107 1JWY ADP 0.00002743 0.53155 3.67816
108 1ION ADP 0.000007464 0.56207 3.7037
109 4JLV ADP 0.0001161 0.49504 3.71747
110 2ZPT A3P 0.01186 0.4477 3.72881
111 3F8K COA 0.02318 0.40451 3.75
112 1J99 AND 0.005334 0.44821 3.75427
113 4TMK T5A 0.004893 0.45016 3.75587
114 3MGB PAP 0.004274 0.43647 3.76176
115 5X40 ACP 0.0002984 0.49813 3.76712
116 3EZ2 ADP 0.0001407 0.49108 3.76884
117 3EC1 GDP 0.000000001277 0.74037 3.79404
118 1NRJ GTP 0.00000001379 0.70937 3.79747
119 5IFS ADP 0.00006808 0.51547 3.79747
120 4QRH 0O2 0.006184 0.42847 3.80952
121 4NON GDP 0.0000000007581 0.52376 3.84615
122 1OFH ADP 0.00008995 0.5096 3.87097
123 1SQ5 ADP 0.000003982 0.52908 3.8961
124 1V8K ANP 0.00001334 0.54327 3.90244
125 5LTJ ADP 0.00009207 0.5062 3.90805
126 1Q19 APC 0.01441 0.41182 3.90805
127 3IUY AMP 0.009041 0.40768 3.94737
128 2HF9 GSP 0.000000004235 0.60392 3.9823
129 5L3V GDP 0.0000003258 0.56426 4.01338
130 5L3S GNP 0.000000878 0.47121 4.02685
131 1F9V ADP 0.000003599 0.53667 4.03458
132 2B8T THM 0.002996 0.44602 4.03587
133 5MEX SZZ 0.006473 0.44843 4.03727
134 5MEX PAP 0.00224 0.44843 4.03727
135 1F6B GDP 0.0000000004351 0.76292 4.0404
136 1CR1 TTP 0.00002761 0.54532 4.05405
137 3BFV ADP 0.000003422 0.55029 4.05904
138 2IXE ATP 0.0001355 0.51321 4.05904
139 4KBF AMP 0.005114 0.41692 4.10959
140 3P4X ADP 0.00004018 0.51693 4.11622
141 2FAH GDP 0.000008193 0.56318 4.13793
142 4LC1 GDP 0.000000001846 0.69676 4.1543
143 4DKX GDP 0.0000000000925 0.75558 4.16667
144 3H86 AP5 0.0002345 0.52031 4.16667
145 4FCW ADP 0.00007297 0.51106 4.18006
146 4ITR GDP 0.00000004811 0.67916 4.18848
147 2NGR GDP 0.00000002798 0.67575 4.18848
148 1GRN GDP 0.00000004827 0.67568 4.18848
149 2QZ4 ADP 0.00003863 0.52742 4.19847
150 2WMO GTP 0.00000002568 0.68163 4.21053
151 1G3Q ADP 0.000002589 0.53802 4.21941
152 3Q9L ATP 0.00007488 0.44408 4.23077
153 2J0V GDP 0.00000004313 0.66669 4.24528
154 4MXP DB4 0.009262 0.41182 4.26829
155 3BD9 A3P 0.003721 0.4072 4.28571
156 1NST A3P 0.00126 0.45863 4.30769
157 1TAD GDP 0.00000000004133 0.85892 4.32099
158 1TAD ALF 0.00000000004133 0.54527 4.32099
159 2OBM ADP 0.0005183 0.47845 4.32277
160 4KAX GTP 0.00000000003143 0.84458 4.34783
161 2BIF SIN 0.0003338 0.52238 4.36782
162 2BIF ANP 0.0002021 0.52222 4.36782
163 3TBK ANP 0.001329 0.4381 4.36782
164 4ZG4 VO4 ADP 0.00007017 0.40946 4.36782
165 4I9B 1KA 0.02866 0.40202 4.36782
166 2ZFI ADP 0.000008412 0.53204 4.37158
167 3ORF NAD 0.02912 0.40731 4.38247
168 3BFX A3P 0.0003981 0.41565 4.39189
169 4FRZ ADP 0.000002766 0.54103 4.40415
170 4PX9 ADP 0.0002483 0.47936 4.45205
171 4WZ6 ATP 0.00001724 0.54987 4.48276
172 5G41 AP5 0.0008051 0.50407 4.4843
173 2FJU GSP 0.0000001258 0.66167 4.49438
174 1S8F GDP 0.00000000219 0.76778 4.51977
175 3B5J 12D 0.00006962 0.51314 4.52675
176 5M7P ADP 0.00005194 0.52925 4.5977
177 1WA5 GTP 0.00000001374 0.47486 4.5977
178 1OYY AGS 0.003817 0.42566 4.5977
179 4IDN GNP 0.00007209 0.41962 4.5977
180 4H1V GNP 0.00000003982 0.57381 4.60705
181 1PUJ GNP 0.00000000001277 0.84684 4.60993
182 3PQC GDP 0.0000001319 0.58168 4.61538
183 3A1S GDP 0.0000007171 0.56933 4.65116
184 2VB6 ADP BEF 0.00007573 0.40919 4.69799
185 2XTN GTP 0.000001937 0.47135 4.70085
186 2A5J GDP 0.000000001135 0.66378 4.71204
187 3QKT ANP 0.0002841 0.50116 4.71976
188 3Q85 GNP 0.00000000009528 0.78954 4.73373
189 2OG2 MLI 0.00001867 0.41988 4.73538
190 5KUT GDP 0.00000002479 0.67829 4.7619
191 1T8U A3P 0.001648 0.45705 4.77941
192 1T8U UAP SGN IDS SGN 0.00534 0.45499 4.77941
193 1OE0 TTP 0.002629 0.45569 4.78261
194 2WOJ ADP ALF 0.000005614 0.42553 4.80226
195 2CE7 ADP 0.00003501 0.52949 4.82759
196 1TQ4 GDP 0.000000004049 0.5749 4.84262
197 2VVG ADP 0.0000001452 0.55203 4.85714
198 3E70 GDP 0.0000008417 0.60449 4.87805
199 4U00 ADP 0.000003479 0.50058 4.91803
200 1RYH GNP 0.00000001653 0.69091 4.92611
201 3N5C GDP 0.000000000004264 0.81403 4.93827
202 1D5C GDP 0.000000001909 0.74462 4.93827
203 3PCR GTP 0.0000000001089 0.59843 4.93827
204 4D81 ADP 0.00001645 0.48258 4.947
205 3QXC ATP 0.00005231 0.40234 4.95868
206 3DEF GDP 0.000001862 0.59461 4.96183
207 2GCO GNP 0.00000002572 0.68911 4.97512
208 2GCN GDP 0.000000042 0.68846 4.97512
209 2Y8E GNP 0.000000002915 0.5357 5.02793
210 4U5X GNP 0.00000004665 0.67982 5.05618
211 5LB3 ADP 0.0002419 0.4799 5.05747
212 2GK6 ADP 0.003149 0.42026 5.05747
213 3FWY ADP 0.0000006821 0.61916 5.09554
214 1UJ2 C5P 0.00002962 0.55482 5.15873
215 1UJ2 ADP 0.00003347 0.55212 5.15873
216 1Z0A GDP 0.00000000048 0.76551 5.17241
217 2A5F GTP 0.00000000002287 0.85889 5.18135
218 1OW3 GDP 0.00000005126 0.6744 5.18135
219 3B7G ANP 0.0006242 0.44093 5.21739
220 3ZQ6 ADP ALF 0.000004483 0.59653 5.24691
221 2FFQ GSP 0.000000002283 0.76405 5.26316
222 1UPT GTP 0.00000000201 0.75439 5.26316
223 4MKF AP5 0.0004252 0.51447 5.28736
224 1YZQ GNP 0.000000002629 0.76093 5.29412
225 2GDJ ANP 0.0001305 0.47924 5.30303
226 5E5U MLI 0.002586 0.44051 5.30303
227 4LJ9 ACP 0.0001341 0.49529 5.30973
228 3CNL GNP 0.0000000001598 0.77337 5.34351
229 1GOJ ADP 0.0000001431 0.67071 5.35211
230 5IRC GDP 0.0000002617 0.63269 5.37634
231 1MH1 GNP 0.0000000612 0.48829 5.37634
232 3A4M ADP 0.000002273 0.56062 5.38462
233 4HDO GNP 0.00000002893 0.70794 5.38922
234 3X1Z GNP 0.00000001702 0.49662 5.38922
235 4D0N GDP 0.000000008501 0.6962 5.40541
236 5HPY GDP 0.00000002094 0.6935 5.40541
237 1CJW COT 0.01037 0.42808 5.42169
238 4XGU ADP 0.00004306 0.45866 5.42453
239 3AQ4 GDP 0.00000000001 0.76883 5.43478
240 1KMQ GNP 0.00000007916 0.67763 5.43478
241 3TK1 GDP 0.0000000002568 0.74219 5.45455
242 4YMU ATP 0.00009386 0.49943 5.45455
243 1KAO GDP 0.000000003364 0.73253 5.51724
244 5KSZ GCP 0.0000002763 0.56864 5.51724
245 2C9O ADP 0.00004649 0.43652 5.51724
246 3DC4 ADP 0.00001828 0.51955 5.52326
247 1FZQ GDP 0.00000000005251 0.80192 5.52486
248 1MR3 G3D 0.00000000008574 0.79692 5.52486
249 1H65 GDP 0.000003691 0.59137 5.55556
250 4XOI GTP 0.0000001335 0.49824 5.55556
251 1NJF AGS 0.00003271 0.54404 5.6
252 1NJF ADP 0.0000287 0.54198 5.6
253 3B9Q MLI 0.000006917 0.57554 5.62914
254 1TX4 ALF GDP 0.0000001876 0.50559 5.64972
255 2ODE ALF GDP 0.00000000005237 0.54356 5.67376
256 2PZE ATP 0.000005829 0.50935 5.67686
257 2Z5F A3P 0.001176 0.46435 5.7047
258 2CJW GDP 0.0000000003623 0.72914 5.72917
259 1IWE IMP 0.00005288 0.60442 5.74713
260 1W0J ADP 0.000002405 0.58918 5.74713
261 1W0J ADP BEF 0.0001306 0.50945 5.74713
262 1A4R GDP 0.00000002782 0.69091 5.75916
263 1A4R GNH 0.00000002521 0.68954 5.75916
264 1XX6 ADP 0.0003101 0.47787 5.75916
265 4HUT ATP 0.02844 0.40664 5.75916
266 4YLG GDP 0.00000000004918 0.67244 5.78035
267 4LPS GDP 0.00000001901 0.63069 5.78512
268 2B8W ALF 5GP 0.0001795 0.51121 5.79268
269 2F3R G5P 0.0159 0.42224 5.7971
270 4GOJ GNP 0.0000000001451 0.81141 5.83333
271 5IRR GSP 0.000001333 0.48571 5.84416
272 1GWN GTP 0.00000001942 0.70199 5.85366
273 3W5J GDP 0.0000000154 0.61681 5.88235
274 2PL3 ADP 0.0005836 0.46174 5.9322
275 4XSH GSP 0.0000000341 0.55884 5.93607
276 1SVK ALF GDP 0.00000000004728 0.85888 5.94901
277 4KVG GTP 0.00000001015 0.7283 5.95238
278 2EW1 GNP 0.00000001786 0.71009 5.97015
279 2BCG GDP 0.00000000429 0.59289 5.97701
280 1P3D ANP 0.009702 0.41872 5.97701
281 1GQY ACP 0.01312 0.40652 5.97701
282 1WF3 GNP 0.0000000005635 0.79495 5.98007
283 1S3G AP5 0.0005767 0.50626 5.99078
284 1CXZ GSP 0.00000003009 0.69569 6.04396
285 3VX3 ADP 0.00005469 0.52814 6.04839
286 2G77 GDP 0.000000000116 0.65968 6.06061
287 1RE0 GDP 0.000000000006542 0.83927 6.09756
288 1S9D GDP 0.00000000001487 0.76148 6.09756
289 3TKL GTP 0.000000009981 0.53183 6.12245
290 3DKP ADP 0.0005663 0.46535 6.12245
291 1JJ7 ADP 0.000001556 0.61722 6.15385
292 5MVR ADP 0.000003767 0.56954 6.17284
293 1X1R GDP 0.00000001996 0.71614 6.2069
294 4PJ3 ANP 0.001799 0.40701 6.2069
295 4WOP CTP 0.0005417 0.40155 6.22222
296 4BQS ADP 0.0000142 0.52218 6.25
297 1KO8 6PG 0.0002437 0.49607 6.28571
298 3IO3 ADP 0.000003037 0.59019 6.32184
299 2CBZ ATP 0.0000008002 0.63272 6.32911
300 1Z06 GNP 0.000000001801 0.55182 6.34921
301 5BW4 SAM 0.02318 0.403 6.36704
302 1Y3A GDP 0.00000000003255 0.84757 6.38298
303 1HSR BHO 0.005915 0.42608 6.39535
304 1UKZ ADP 0.000436 0.50484 6.40394
305 4R43 GDP 0.000008719 0.53274 6.43678
306 2DPY ADP 0.00006605 0.51425 6.43678
307 1YQT ADP 0.00002125 0.50288 6.43678
308 4MKG AP5 0.0003585 0.5172 6.45161
309 2OM2 GDP 0.00000000003589 0.64209 6.46154
310 1YZN GNP 0.00000001884 0.50571 6.48649
311 1YRB GDP 0.0000000007381 0.64827 6.48855
312 1M7B GTP 0.00000001267 0.56 6.52174
313 3EWA ANP 0.0000733 0.50785 6.52174
314 5N69 ADP 0.00004864 0.4604 6.53266
315 1O3Y GTP 0.0000000001107 0.82088 6.62651
316 2J59 GTP 0.00000000003147 0.61048 6.62651
317 3SFV GDP 0.000000006579 0.72534 6.62983
318 1BH2 GSP 0.0000000001913 0.82479 6.66667
319 3H4S ADP 0.0000006455 0.54753 6.66667
320 3LXR GDP 0.00000003333 0.60586 6.77083
321 4RZ3 ADP 0.0000406 0.53195 6.77966
322 2D2F ADP 0.0001098 0.4296 6.8
323 3NKV GNP 0.00000001009 0.72842 6.85714
324 2QEN ADP 0.000008813 0.56455 6.85714
325 5GOE GDP 0.0000000003411 0.68061 6.87204
326 2HT6 GDP 0.00000000005655 0.79479 6.89655
327 3TNF GNP 0.000000008318 0.73818 6.89655
328 3QBT GNP 0.000000006475 0.5266 6.89655
329 4OI4 ATP 0.0001342 0.51555 6.95652
330 5WDR GNP 0.000000007808 0.51289 7.01754
331 4BAS GNP 0.0000000002554 0.79914 7.03518
332 1GP2 GDP 0.00000000002838 0.61303 7.04225
333 2ZEJ GDP 0.000000003138 0.75701 7.06522
334 1LVG ADP 0.0000005417 0.58999 7.07071
335 3KJI ADP 0.000009819 0.55934 7.08661
336 3KTA AP5 0.00005575 0.45565 7.14286
337 1BO4 COA 0.00298 0.4183 7.14286
338 3NHB ADP 0.00001561 0.55207 7.18954
339 3FVQ ATP 0.0002182 0.41077 7.24234
340 5L3R GCP 0.0000005047 0.47595 7.30897
341 4A4Z ANP 0.001047 0.4409 7.35632
342 4LHW GNP 0.00000002044 0.51383 7.47126
343 2D7D ADP 0.002346 0.43579 7.5
344 2GJ8 ALF GDP 0.000000001349 0.53235 7.55814
345 1IHU AF3 0.000002426 0.60047 7.58621
346 1IHU ADP 0.000002727 0.60047 7.58621
347 4QM7 GTP 0.00005922 0.51228 7.60234
348 3RAB GNP 0.000000002158 0.76236 7.69231
349 1GXU 2HP 0.0009911 0.44899 7.69231
350 4KVX ACO 0.02149 0.40905 7.69231
351 1ZUI SKM 0.0001199 0.53697 7.7381
352 1G6H ADP 0.000003582 0.59539 7.7821
353 2W83 GTP 0.00000000004931 0.60573 7.79221
354 3DDC GNP 0.00000003275 0.7052 7.83133
355 1G4U GDP 0.0000000967 0.54617 7.8329
356 1ZD9 GDP 0.0000000004208 0.62143 7.97872
357 1ZJ6 G3D 0.000000000003434 0.78733 8.02139
358 2W9S NDP 0.02292 0.40896 8.07453
359 2AWN ADP 0.0000009175 0.63016 8.13648
360 3RLF ANP 0.0001894 0.50804 8.13648
361 1Y63 ADP 0.000001329 0.59119 8.15217
362 1FQK GDP 0.00000000005362 0.60641 8.16327
363 2Q2Y ADP 0.0001033 0.54583 8.17439
364 2Q2Y MKR 0.000108 0.5435 8.17439
365 5EE5 GTP 0.000000002873 0.74664 8.18713
366 1AZT GSP 0.00000000002089 0.87411 8.20895
367 1G16 GDP 0.00000002095 0.70354 8.23529
368 1Z2A GDP 0.0000000007013 0.57116 8.33333
369 5J1S ATP 0.0001259 0.40294 8.3682
370 1CS4 GSP 0.00000000003826 0.55762 8.37563
371 1B0U ATP 0.000166 0.44067 8.39695
372 2IYL GDP 0.0000007233 0.58219 8.4507
373 1R4A GNP 0.0000000009576 0.77711 8.48485
374 3T5G GDP 0.0000000007213 0.75693 8.55263
375 1VG1 GDP 0.0000000002732 0.77266 8.64865
376 1VG9 GDP 0.0000000006655 0.75402 8.64865
377 5BXQ GDP 0.0000000009729 0.74607 8.66142
378 4YC7 GNP 0.00000005048 0.68447 8.66142
379 2C04 GCP 0.000004961 0.49651 8.75421
380 1QF9 C5P 0.0007385 0.49691 8.76289
381 2ZTS ADP 0.00008377 0.43012 8.76494
382 3IIJ ADP 0.000005209 0.5628 8.88889
383 1YZG GDP 0.000000000008321 0.84576 8.93855
384 4DSU GDP 0.000000004633 0.74841 8.99471
385 2WKQ GTP 0.0000001655 0.5059 9.03614
386 5TB5 GDP 0.000000001582 0.65761 9.18919
387 5TAR GDP 0.000000002262 0.63343 9.18919
388 1Z08 GNP 0.000000009819 0.54178 9.41177
389 4CVN ADP 0.000006245 0.56426 9.42408
390 5KSP GDP 0.00000002329 0.62752 9.47368
391 1MKY GDP 0.000000000006736 0.8446 9.88506
392 4DCT GDP 0.0000000003396 0.70697 9.88506
393 1TU3 GNP 0.000000002004 0.76398 9.94152
394 5XCO GDP 0.00000000414 0.7242 9.94152
395 1R2Q GNP 0.000000003143 0.77465 10
396 4R2I ANP 0.001293 0.45118 10
397 5H67 ATP 0.003002 0.4074 10
398 5UQW GDP 0.000000005428 0.53948 10.0529
399 5E95 GDP 0.00000001589 0.58728 10.119
400 1GUA GNP 0.00000001907 0.50397 10.1796
401 2QTV GNP 0.00000001154 0.7226 10.2041
402 3KUD GDP 0.000000005353 0.72979 10.241
403 1NVV GNP 0.00000002729 0.70923 10.241
404 1NVU GTP 0.00000002797 0.70869 10.241
405 1WQ1 GDP 0.00000001057 0.53897 10.241
406 1CLU DBG 0.00000003144 0.40963 10.241
407 3V2U ATP 0.01282 0.41437 10.3448
408 4KFU ACP 0.000001686 0.55118 10.3774
409 2C5L GTP 0.000000006947 0.73946 10.4046
410 3DOE GTP 0.00000000006704 0.83182 10.4167
411 2QG6 NMN 0.0001805 0.51667 10.5528
412 5I0H ADP BEF 0.00007301 0.52433 10.5747
413 5IRN ADP 0.00001041 0.48601 10.5747
414 3MJH GTP 0.000000001926 0.53987 10.7143
415 1KSH GDP 0.0000000001451 0.80765 10.7527
416 2UZI GTP 0.000000008812 0.73141 10.8434
417 4K81 GTP 0.00000004533 0.70057 11.1111
418 3TMK T5A 0.0001312 0.52552 11.1111
419 5O2T GSP 0.000000009754 0.51297 11.2426
420 1OXV ANP 0.00004668 0.51383 11.3314
421 3WYF GTP 0.000000009072 0.73625 11.3445
422 5DI3 GNP 0.0000000001443 0.60813 11.4068
423 4TTQ ATP 0.00001844 0.53654 11.4943
424 3CH5 GDP 0.0000000008518 0.74886 11.5385
425 1B7T ADP 0.00005904 0.46837 11.5385
426 1QF5 GDP 0.00003948 0.57899 11.6009
427 1QF5 RPL 0.01159 0.47206 11.6009
428 1ZUA NAP 0.04247 0.41774 11.6719
429 1ZUA TOL 0.04247 0.41774 11.6719
430 3GJX GTP 0.00000003057 0.70672 11.7241
431 2A9K GDP 0.000000003091 0.73433 11.7647
432 3REF GDP 0.0000000431 0.52878 11.8557
433 1FQJ GDP 0.00000000003067 0.61156 11.9048
434 1HTW ADP 0.000006389 0.56205 12.0253
435 5BQ5 ADP BEF 0.0000867 0.46449 12.1693
436 4XTR ADP 0.000002644 0.48737 12.1739
437 4XTR ATP 0.000003814 0.45323 12.1739
438 4XVU ATP 0.000005228 0.45009 12.1739
439 1XTQ GDP 0.000000001334 0.76664 12.4294
440 1UAD GNP 0.000000007472 0.73504 12.5714
441 2EFE GNH 0.000000007835 0.71067 12.7072
442 4ZI2 GNP 0.0000000002739 0.59934 12.782
443 3D2M COA 0.03246 0.40364 12.8736
444 1KK8 BEF ADP 0.00004282 0.45114 12.9496
445 2KIN ADP 0.000000101 0.55695 13
446 3M1I GTP 0.00000001084 0.72963 13.089
447 1U8Z GDP 0.000000005067 0.54848 13.0952
448 4E03 ADP 0.00005025 0.51888 13.1068
449 5UFQ GNP 0.000000005951 0.52548 13.1148
450 1FP6 ADP 0.000004664 0.49968 13.1488
451 4DID GDP 0.000000016 0.68745 13.1579
452 4M9Q GNP 0.0000000000634 0.61711 13.2159
453 1SVI GDP 0.000000004407 0.70496 13.3333
454 5KDO GDP 0.00000000001682 0.65124 13.5135
455 2RGX AP5 0.0008552 0.49946 13.5922
456 1GOT GDP 0.00000000003029 0.84538 13.6986
457 4WZA ACP 0.00005151 0.58174 13.7681
458 4WZA ADP 0.00005151 0.58174 13.7681
459 3BC1 GNP 0.000000008329 0.73265 13.8462
460 2V7Q ATP 0.00000285 0.58236 14
461 2V7Q ADP 0.0001181 0.49794 14
462 2CK3 ANP 0.0001653 0.42347 14
463 1VM6 NAD 0.0208 0.40979 14.0351
464 4AG5 ADP 0.00001464 0.55318 14.2857
465 3CPJ GDP 0.000000007227 0.71238 14.3498
466 3AB3 GDP 0.00000000002808 0.84309 14.3646
467 1ZCB GDP 0.00000000005802 0.84191 14.3646
468 1Z0K GTP 0.000000006833 0.54813 14.4928
469 1Z0F GDP 0.0000000005269 0.75891 14.5251
470 3ZIA ADP 0.000006225 0.56901 14.7482
471 3ZIA ATP 0.00000572 0.56437 14.7482
472 1LFD GNP 0.00000001192 0.72476 14.9425
473 2IS6 ADP 0.00009385 0.50271 15.1724
474 1NF3 GNP 0.0000001152 0.4894 15.3846
475 1J2J GTP 0.0000000004006 0.58217 15.5556
476 4HI0 GDP 0.0000000005803 0.60384 15.5779
477 2F9L GDP 0.0000000008659 0.56912 15.5779
478 1DS6 GDP 0.00000001345 0.68666 15.625
479 1WDT GTP 0.00000002605 0.56388 15.6322
480 1OIX GDP 0.000000001975 0.7643 15.7068
481 3E5H GNP 0.00000005283 0.69201 15.7303
482 3QF7 ANP 0.0001928 0.5011 16
483 2BME GNP 0.000000006142 0.73935 16.129
484 1I4D GDP 0.00000002869 0.66632 16.1458
485 3T1O GDP 0.000000000004157 0.86561 16.1616
486 3T12 GDP ALF 0.00000000002212 0.62829 16.1616
487 3FB4 AP5 0.0005307 0.50818 16.2037
488 2W2X GSP 0.00000002665 0.69515 16.2162
489 1OIV GDP 0.000000002643 0.7579 16.2304
490 1W7J ADP BEF 0.00004805 0.44927 16.5563
491 3SBD GNP 0.0000003657 0.47901 16.5775
492 1E96 GTP 0.0000001783 0.66525 16.6667
493 1Z0J GTP 0.00000000936 0.51326 17.0588
494 3RWO GDP 0.0000000008331 0.7833 17.2973
495 5JCZ GDP 0.000000005094 0.58385 17.3184
496 2HV8 GTP 0.000000005836 0.74047 17.4419
497 4LX0 BEF GDP 0.000000006475 0.74101 17.5141
498 1HE1 GDP 0.0000001073 0.53401 17.6136
499 3CX8 GSP 0.00000000009442 0.84052 17.7515
500 1YVD GNP 0.00000001311 0.52085 17.7515
501 4C4P GNP 0.000000003506 0.75457 17.9191
502 2D7C GTP 0.000000002185 0.76209 17.9641
503 2WIC GNP 0.000000000003775 0.78514 17.9775
504 4R98 GNH 0.000000000007586 0.80364 18.0812
505 1NN5 ANP 0.0000554 0.5482 18.1395
506 2PEZ DAT 0.00001864 0.57438 18.4358
507 4YDS ATP 0.00001636 0.54384 18.8596
508 5SZH GNP 0.000000007323 0.73829 18.9542
509 4H6U ACO 0.01775 0.40727 20
510 1KY3 GDP 0.000000004693 0.72154 20.3297
511 3Q72 GNP 0.000000000251 0.76405 20.4819
512 2WJG GDP 0.00000000001063 0.79677 20.7447
513 2FH5 GTP 0.00000000149 0.7574 21.4953
514 3WYG GTP 0.000000006744 0.74283 22.3684
515 4D0G GTP 0.000000001364 0.76279 23.1884
516 2WJH GDP 0.00000000005065 0.80794 23.494
517 2WJH FLC 0.000000026 0.68137 23.494
518 1EK0 GNP 0.00000001892 0.7146 24.7059
519 3ZS9 ADP ALF 0.000004741 0.42724 26.3158
520 1ZC3 GNP 0.00000001014 0.73109 26.5487
521 4HDQ GNP 0.00000005785 0.69263 26.9231
522 4PSW COA 0.008693 0.4153 28.9474
523 4ZKD GDP 0.0000000002925 0.54874 31.2644
524 4TMZ GSP 0.000000001095 0.57218 33.3333
525 2VOH CIT 0.02334 0.40214 34.6154
526 4V0K GDP 0.0000000001709 0.57832 36.0947
Pocket No.: 2; Query (leader) PDB : 1SKQ; Ligand: GDP; Similar sites found: 19
This union binding pocket(no: 2) in the query (biounit: 1skq.bio2) has 17 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 4DP3 MMV 0.01942 0.42272 1.6092
2 1X6V ADP 0.00005587 0.40308 1.74603
3 2B6N ALA PRO THR 0.02599 0.40045 1.79856
4 3VM7 GLC 0.02115 0.40318 1.83908
5 5FJJ MAN 0.00002118 0.57548 2.75862
6 4M7V RAR 0.03589 0.40802 2.85714
7 3RG9 WRA 0.03121 0.40681 2.91667
8 3RG9 NDP 0.02863 0.40681 2.91667
9 4AF0 IMP 0.01806 0.40065 3.21839
10 2BL9 CP6 0.03856 0.40019 3.36134
11 3W9F I3P 0.01018 0.41555 3.67816
12 2YOH WMJ 0.00002639 0.40101 3.80952
13 4KVA GTP 0.000001552 0.40158 4.12621
14 3Q9T FAY 0.04199 0.40017 5.97701
15 5EW9 5VC 0.04447 0.4285 6.27306
16 1AOE GW3 0.04133 0.40142 7.29167
17 5K5Z ANP 0.0003571 0.4043 10.5096
18 2Q46 NAP 0.02114 0.40569 11.8577
19 1HE1 AF3 0.02174 0.40014 17.6136
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