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Receptor
PDB id Resolution Class Description Source Keywords
1SMR 2 Å EC: 3.4.23.15 THE 3-D STRUCTURE OF MOUSE SUBMAXILLARY RENIN COMPLEXED WITH DECAPEPTIDE INHIBITOR CH-66 BASED ON THE 4-16 FRAGMENT OF RA NGIOTENSINOGEN MUS MUSCULUS ASPARTIC PROTEINASE HYDROLASE-HYDROLASE INHIBITOR COMPLEX
Ref.: X-RAY ANALYSIS AT 2.0 A RESOLUTION OF MOUSE SUBMAXI RENIN COMPLEXED WITH A DECAPEPTIDE INHIBITOR CH-66, THE 4-16 FRAGMENT OF RAT ANGIOTENSINOGEN. J.MOL.BIOL. V. 236 342 1994
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
PIV HIS PRO PHE HIS LPL TYR TYR SER B:1;
D:1;
F:1;
H:1;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
submit data
1246.5 n/a O=C([...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1SMR 2 Å EC: 3.4.23.15 THE 3-D STRUCTURE OF MOUSE SUBMAXILLARY RENIN COMPLEXED WITH DECAPEPTIDE INHIBITOR CH-66 BASED ON THE 4-16 FRAGMENT OF RA NGIOTENSINOGEN MUS MUSCULUS ASPARTIC PROTEINASE HYDROLASE-HYDROLASE INHIBITOR COMPLEX
Ref.: X-RAY ANALYSIS AT 2.0 A RESOLUTION OF MOUSE SUBMAXI RENIN COMPLEXED WITH A DECAPEPTIDE INHIBITOR CH-66, THE 4-16 FRAGMENT OF RAT ANGIOTENSINOGEN. J.MOL.BIOL. V. 236 342 1994
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 1SMR - PIV HIS PRO PHE HIS LPL TYR TYR SER n/a n/a
70% Homology Family (40)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 1HRN ic50 = 9 nM 03D C30 H49 N O5 CC(C)C[C@@....
2 2V0Z ic50 = 0.0006 uM C41 C30 H53 N3 O6 CC(C)[C@@H....
3 3OWN Ki = 34 nM 3OX C37 H48 N4 O7 S CC(C)CNC(=....
4 2G21 - L1B C19 H24 N5 O CCc1c(c(nc....
5 4RYC ic50 = 0.08 uM 3ZK C27 H39 N3 O6 S Cc1ccc(cc1....
6 3D91 Kd = 131 pM REM C33 H50 N4 O6 S CC(C)(C)S(....
7 1BIL ic50 = 0.5 nM 0IU C34 H53 N5 O5 S NULL
8 3KM4 ic50 = 1.3 nM 22X C28 H45 Cl N4 O3 CC(=O)NCCC....
9 2G24 - 7IG C19 H19 F2 N5 CCc1c(c(nc....
10 2IL2 Kd = 79 nM LIX C32 H38 N6 O5 S CCc1c(c(nc....
11 5SY3 ic50 = 43 uM 74Z C15 H15 N3 O S c1cc(oc1)C....
12 4Q1N ic50 = 0.2 nM 2Y9 C26 H42 N4 O4 CCOC[C@@H]....
13 2I4Q ic50 = 0.007 uM UA4 C25 H27 F2 N5 O3 CCc1c(c(nc....
14 2BKS ic50 = 37 nM PZ1 C34 H41 N3 O6 COc1ccccc1....
15 4S1G Ki = 0.6 nM 43T C24 H29 F N4 O2 C[C@@H](c1....
16 4XX3 Ki = 56 nM 70X C23 H28 N4 O2 [H]/N=C1/N....
17 2G1S - 4IG C24 H25 F2 N5 O3 CCc1c(c(nc....
18 2G20 - L1A C33 H50 N6 O7 S2 CC(C)C[C@@....
19 5SXN ic50 = 11 uM 74U C19 H15 N3 O c1ccc(cc1)....
20 3G70 ic50 = 0.29 nM A5T C33 H32 Cl3 F2 N3 O2 c1cc(c(c(c....
21 2G1Y - 5IG C20 H27 N5 O3 CCc1c(c(nc....
22 2G1R - 3IG C20 H26 N6 O3 CCc1c(c(nc....
23 4GJC ic50 = 0.09 uM 0MJ C27 H29 N3 O4 S Cc1ccc(cc1....
24 4GJ8 - 0LW C20 H23 N O S c1ccc2c(c1....
25 5SY2 ic50 = 11 uM 74V C18 H25 N5 O2 CCN([C@H]1....
26 5KOS ic50 = 0.79 nM 6VS C27 H46 N6 O4 CC(C)CN([C....
27 3G72 ic50 = 0.29 nM A6T C33 H32 Cl3 F2 N3 O2 c1cc(c(c(c....
28 3G6Z ic50 = 0.2 nM A7T C35 H39 Cl2 N3 O3 Cc1cccc(c1....
29 3GW5 ic50 = 0.47 nM 72X C28 H46 Cl N3 O3 CNC[C@H](C....
30 3SFC ic50 = 0.003 uM S53 C32 H29 F N4 O2 Cc1ccc(cc1....
31 2IKO Kd = 3571 nM 7IG C19 H19 F2 N5 CCc1c(c(nc....
32 3K1W - BFX C31 H31 Br Cl F N2 O2 c1ccc(c(c1....
33 4XX4 Ki = 44 nM 70Y C25 H30 N4 O2 [H]/N=C1/N....
34 2FS4 ic50 = 37 nM PZ1 C34 H41 N3 O6 COc1ccccc1....
35 2BKT ic50 = 23 nM RPF C31 H37 N3 O5 COc1ccccc1....
36 4GJ5 - 0LR C22 H23 N O c1ccc(cc1)....
37 2G22 - 6IG C27 H35 N5 O CCc1c(c(nc....
38 1RNE ic50 = 2 nM C60 C39 H63 N5 O6 S CCCCNC(=O)....
39 2G26 - 3LG C32 H35 N3 O7 COc1ccccc1....
40 1SMR - PIV HIS PRO PHE HIS LPL TYR TYR SER n/a n/a
50% Homology Family (159)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 1E81 - M91 C34 H49 N5 O6 S CSC[C@@H](....
2 4ZEA - IMI C10 H17 N3 O2 S C1[C@H]2[C....
3 3ER3 Ki = 81 nM 0EL C51 H78 N8 O9 NULL
4 4Y4D - CFF C8 H10 N4 O2 Cn1cnc2c1C....
5 5LWT - 7B3 C10 H13 N3 O Cc1c2cnnc(....
6 1EPM - THR PHE GLN ALA PSA LEU ARG GLU n/a n/a
7 1EED Ki = 16.2 uM 0EO C34 H55 N3 O8 CC(C)C[C@@....
8 3PMY - 41L C15 H13 N3 O c1ccc(cc1)....
9 1OEX - BOC HIS PRO PHE ALA LOV ILE HIS n/a n/a
10 4ER4 Ki = 160 nM PRO HIS PRO PHE HIS LAV ILE HIS LYS n/a n/a
11 4LBT Ki = 6 uM 1TZ C21 H24 N4 O Cc1cc(c(c(....
12 3PWW - ROC C38 H50 N6 O5 CC(C)(C)NC....
13 4Y38 Kd = 4 mM 0A9 C10 H13 N O2 COC(=O)[C@....
14 2JJJ - 0QS C36 H56 F2 N7 O8 S CC(C)(C)S(....
15 1GVV - 0GM C51 H61 N5 O6 CC(C)C[C@H....
16 3PMU - F7L C14 H20 F N O2 c1ccc(c(c1....
17 5OJE ic50 = 12.9 uM VSK C22 H27 N3 O Cc1cc(c(c(....
18 1GVT - 2ZS C31 H48 N4 O7 S CC(C)OC(=O....
19 1EPR - 0QS C36 H56 F2 N7 O8 S CC(C)(C)S(....
20 5MB5 - 46P C8 H10 N4 S Cc1c(sc(n1....
21 5MB7 - 4AV C8 H9 Cl N2 O2 CNCc1cc(cc....
22 4Y4G - GGB C5 H12 N4 O3 [H]/N=C(N)....
23 3ER5 Ki = 1 nM PRO HIS PRO PHE HIS STA VAL ILE HIS LYS n/a n/a
24 3URL - HIS SER LEU PHE HIS PUK THR PRO n/a n/a
25 3PCZ - BAM C7 H9 N2 c1ccc(cc1)....
26 2V00 Kd = 0.22 mM V15 C12 H13 N3 O c1ccc(cc1)....
27 5LWR - 7B2 C27 H29 Cl N9 O Cc1c2cnn3c....
28 3PLL - F06 C8 H9 Cl N2 S [H]/N=C(N)....
29 4ER2 Ki = 0.5 nM IVA VAL VAL STA ALA STA n/a n/a
30 4LP9 ic50 = 0.62 uM SER LEU PHE HIS 22G THR PRO n/a n/a
31 3PRS - RIT C37 H48 N6 O5 S2 CC(C)c1nc(....
32 1ENT Ki = 110 nM 0EM C32 H52 N6 O7 P NULL
33 1E80 - 0GQ C41 H64 N10 O6 CC[C@H](C)....
34 5LWS - 7B2 C27 H29 Cl N9 O Cc1c2cnn3c....
35 3PBD - F05 C8 H8 N2 c1ccc2c(c1....
36 1OD1 - 0QS C36 H56 F2 N7 O8 S CC(C)(C)S(....
37 3WZ6 Ki = 1.1 uM IXZ C27 H25 N3 O2 S c1ccc(cc1)....
38 5ER1 Ki = 960 nM 0HT C28 H48 N4 O5 CC[C@H](C)....
39 1OEW - SER THR n/a n/a
40 1EPQ Ki = 6.5 nM 0QF C31 H52 N4 O7 S2 CCS[C@@H](....
41 5MB3 - 5GL C13 H20 N2 O S CCCN1C2=C(....
42 2JJI - 0QS C36 H56 F2 N7 O8 S CC(C)(C)S(....
43 3PCW - FBF C8 H7 F3 N2 [H]/N=C(/c....
44 3PGI - F41 C14 H18 N2 O3 c1cc2c(cc1....
45 4Y3J Kd = 6.8 mM HIC C7 H11 N3 O2 Cn1cc(nc1)....
46 1GVW Ki = 110 nM 0EM C32 H52 N6 O7 P NULL
47 5ER2 Ki = 0.27 uM 0EK C50 H77 N9 O9 NULL
48 1EPP Ki = 69 nM 1Z1 C32 H57 N7 O6 S2 CC[C@H](C)....
49 2ER7 ic50 = 0.7 nM BOC HIS PRO PHE HIS LOV ILE HIS n/a n/a
50 4KUP Ki = 6 uM 1TZ C21 H24 N4 O Cc1cc(c(c(....
51 3WZ7 Ki = 1.8 uM IXY C28 H30 N4 O2 S c1ccc(cc1)....
52 1EPO Ki = 11 nM 2Z3 C32 H49 F2 N5 O7 NULL
53 1ER8 - DHI PRO PHE HIS LEU LEU VAL TYR n/a n/a
54 3WZ8 Ki = 1.5 uM IXV C27 H25 N3 O2 S c1ccc(cc1)....
55 3PI0 - F91 C14 H14 N2 O2 c1cc2c(cc1....
56 1GVU Ki = 1 nM PRO HIS PRO PHE HIS STA VAL ILE HIS LYS n/a n/a
57 1EPL - PRO LEU GLU PSA ARG LEU n/a n/a
58 4Y3Y Kd = 4.5 mM DCL C6 H15 N O CC(C)C[C@@....
59 1E5O - 3AI C23 H38 N4 O4 S CC[C@H](C)....
60 3PLD - F90 C8 H9 Cl N2 S [H]/N=C(N)....
61 5MB0 Kd = 1.4 mM F91 C14 H14 N2 O2 c1cc2c(cc1....
62 2ER6 Ki = 60 nM PRO THR GLU PUK ARG GLU n/a n/a
63 3URI - PRO HIS LEU SER PHE MET ALA HIS n/a n/a
64 4LHH Ki = 6 uM 1TZ C21 H24 N4 O Cc1cc(c(c(....
65 4Y48 - GLY PRO n/a n/a
66 1E82 - M90 C34 H49 N5 O6 S CSC[C@@H](....
67 1EPN - 2ZS C31 H48 N4 O7 S CC(C)OC(=O....
68 2ER9 Ki = 40 nM BOC HIS PRO PHE HIS STA LEU PHE n/a n/a
69 4Y4J Kd = 3.4 mM LNR C8 H11 N O3 c1cc(c(cc1....
70 1GVX Ki = 60 nM PRO THR GLU PUK ARG GLU n/a n/a
71 3PM4 - F5N C15 H13 N3 O c1ccc(cc1)....
72 3PB5 - F63 C11 H12 N2 O2 CNCc1ccc(o....
73 4ZE6 Kd = 3.3 mM 011 C7 H15 N O2 C(CCCN)CCC....
74 3PBZ - F02 C11 H17 N3 O CCN(CC)c1c....
75 4ER1 Ki = 0.24 uM 0ZP C51 H68 N5 O4 CC[C@H](C)....
76 3OWN Ki = 34 nM 3OX C37 H48 N4 O7 S CC(C)CNC(=....
77 2G21 - L1B C19 H24 N5 O CCc1c(c(nc....
78 4RYC ic50 = 0.08 uM 3ZK C27 H39 N3 O6 S Cc1ccc(cc1....
79 3D91 Kd = 131 pM REM C33 H50 N4 O6 S CC(C)(C)S(....
80 1BIL ic50 = 0.5 nM 0IU C34 H53 N5 O5 S NULL
81 3KM4 ic50 = 1.3 nM 22X C28 H45 Cl N4 O3 CC(=O)NCCC....
82 2G24 - 7IG C19 H19 F2 N5 CCc1c(c(nc....
83 2IL2 Kd = 79 nM LIX C32 H38 N6 O5 S CCc1c(c(nc....
84 5SY3 ic50 = 43 uM 74Z C15 H15 N3 O S c1cc(oc1)C....
85 4Q1N ic50 = 0.2 nM 2Y9 C26 H42 N4 O4 CCOC[C@@H]....
86 2I4Q ic50 = 0.007 uM UA4 C25 H27 F2 N5 O3 CCc1c(c(nc....
87 2BKS ic50 = 37 nM PZ1 C34 H41 N3 O6 COc1ccccc1....
88 4S1G Ki = 0.6 nM 43T C24 H29 F N4 O2 C[C@@H](c1....
89 4XX3 Ki = 56 nM 70X C23 H28 N4 O2 [H]/N=C1/N....
90 2G1S - 4IG C24 H25 F2 N5 O3 CCc1c(c(nc....
91 2G20 - L1A C33 H50 N6 O7 S2 CC(C)C[C@@....
92 5SXN ic50 = 11 uM 74U C19 H15 N3 O c1ccc(cc1)....
93 3G70 ic50 = 0.29 nM A5T C33 H32 Cl3 F2 N3 O2 c1cc(c(c(c....
94 2G1Y - 5IG C20 H27 N5 O3 CCc1c(c(nc....
95 2G1R - 3IG C20 H26 N6 O3 CCc1c(c(nc....
96 4GJC ic50 = 0.09 uM 0MJ C27 H29 N3 O4 S Cc1ccc(cc1....
97 4GJ8 - 0LW C20 H23 N O S c1ccc2c(c1....
98 5SY2 ic50 = 11 uM 74V C18 H25 N5 O2 CCN([C@H]1....
99 5KOS ic50 = 0.79 nM 6VS C27 H46 N6 O4 CC(C)CN([C....
100 3G72 ic50 = 0.29 nM A6T C33 H32 Cl3 F2 N3 O2 c1cc(c(c(c....
101 3G6Z ic50 = 0.2 nM A7T C35 H39 Cl2 N3 O3 Cc1cccc(c1....
102 3GW5 ic50 = 0.47 nM 72X C28 H46 Cl N3 O3 CNC[C@H](C....
103 3SFC ic50 = 0.003 uM S53 C32 H29 F N4 O2 Cc1ccc(cc1....
104 2IKO Kd = 3571 nM 7IG C19 H19 F2 N5 CCc1c(c(nc....
105 3K1W - BFX C31 H31 Br Cl F N2 O2 c1ccc(c(c1....
106 4XX4 Ki = 44 nM 70Y C25 H30 N4 O2 [H]/N=C1/N....
107 2FS4 ic50 = 37 nM PZ1 C34 H41 N3 O6 COc1ccccc1....
108 2BKT ic50 = 23 nM RPF C31 H37 N3 O5 COc1ccccc1....
109 4GJ5 - 0LR C22 H23 N O c1ccc(cc1)....
110 2G22 - 6IG C27 H35 N5 O CCc1c(c(nc....
111 1RNE ic50 = 2 nM C60 C39 H63 N5 O6 S CCCCNC(=O)....
112 2G26 - 3LG C32 H35 N3 O7 COc1ccccc1....
113 4Y6M - 48Q C39 H52 N4 O4 CCCN(CCC)C....
114 5YIE Ki = 5.6 nM 8VF C39 H51 N5 O6 S CCN(CCN)c1....
115 5YID Ki = 4 nM K95 C37 H44 N4 O6 S2 CC1([C@H](....
116 2IGX - A1T C41 H49 N5 O2 CCCCCc1ccc....
117 5YIC Ki = 1.3 nM 8VO C37 H45 N5 O6 S2 CC1([C@H](....
118 4CKU ic50 = 0.15 uM P2F C38 H52 N4 O6 S CCCN(CCC)C....
119 1XDH - IVA VAL VAL STA ALA STA n/a n/a
120 1LF2 - R37 C32 H41 N3 O4 Cc1cccc(c1....
121 5YIB Ki = 3.3 nM 8VC C40 H53 N5 O6 S Cc1cc(cc(c....
122 1LEE - R36 C32 H41 N3 O4 Cc1cccc(c1....
123 5YIA Ki = 3 nM 8V9 C37 H44 N4 O7 S2 CC1([C@H](....
124 1XE5 - 5FE C29 H47 F6 N5 O9 C[C@@H](C(....
125 1PPM Ki = 1600 nM 0P1 C29 H40 N3 O9 P C[C@@H](C(....
126 2WED Ki = 0.8 uM PP6 C29 H32 N2 O7 P CC(C)[C@H]....
127 1APU Ki = 1.6 nM IVA VAL VAL STA EHN n/a n/a
128 2WEC Ki = 110 uM PP5 C28 H32 N2 O7 P CC(C)[C@@H....
129 1APW Ki = 10 nM IVA VAL VAL DFI NME n/a n/a
130 1PPL Ki = 2.8 nM 1Z7 C30 H50 N3 O8 P CC(C)C[C@H....
131 2WEB Ki = 7.6 uM PP4 C28 H32 N2 O7 P CC(C)[C@@H....
132 2WEA - PP6 C29 H32 N2 O7 P CC(C)[C@H]....
133 1BXO Ki = 0.1 nM PP7 C30 H47 N4 O9 P CC(C)C[C@@....
134 1APT - IVA VAL VAL LTA n/a n/a
135 1PPK Ki = 22 nM IVV C24 H46 N3 O7 P CCOC(=O)C[....
136 1BXQ Ki = 42 nM PP8 C29 H47 N4 O9 P CC(C)C[C@H....
137 1APV Ki = 1 nM IVA VAL VAL DFO NME n/a n/a
138 1SMR - PIV HIS PRO PHE HIS LPL TYR TYR SER n/a n/a
139 1QRP - HH0 C36 H60 N5 O10 P C[C@@H](C(....
140 1PSO - IVA VAL VAL STA ALA STA n/a n/a
141 2QZX ic50 = 6 nM IVA VAL VAL STA ALA STA n/a n/a
142 2JXR Ki = 90 nM 2Z3 C32 H49 F2 N5 O7 NULL
143 1FQ5 Ki = 4 nM 0GM C51 H61 N5 O6 CC(C)C[C@H....
144 1QS8 - IVA VAL VAL STA ALA STA n/a n/a
145 1ZAP Ki = 0.17 nM A70 C42 H70 N6 O5 CCCC[C@@H]....
146 1IZE - IVA VAL VAL STA ALA STA n/a n/a
147 1WKR - IVA VAL VAL STA ALA STA n/a n/a
148 5N7Q - IVA VAL VAL STA ALA STA n/a n/a
149 5N70 Kd ~ 3 nM ALA PHE ARG ILE PRO LEU THR ARG n/a n/a
150 3EMY - IVA VAL VAL STA ALA STA n/a n/a
151 2H6T Ki = 60 nM IVA VAL VAL STA ALA STA n/a n/a
152 3FV3 Kd = 0.3 nM IVA VAL VAL STA ALA STA n/a n/a
153 5HCT ic50 = 0.054 uM 61P C30 H30 N8 O2 c1ccc2c(c1....
154 3QVI - K95 C37 H44 N4 O6 S2 CC1([C@H](....
155 3APR - DHI PRO PHE HIS PUK VAL TYR n/a n/a
156 6APR Ki < 17 nM IVA VAL VAL STA ALA STA n/a n/a
157 5APR Ki < 17 nM HIS PRO PHE CYS STA LEU PHE DHL n/a n/a
158 4APR Ki = 200 nM IVA HIS PRO PHE HIS STA LEU PHE n/a n/a
159 1CZI - PRO PHI SMC NOR n/a n/a
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: PIV HIS PRO PHE HIS LPL TYR TYR SER; Similar ligands found: 28
No: Ligand ECFP6 Tc MDL keys Tc
1 PIV HIS PRO PHE HIS LPL TYR TYR SER 1 1
2 BOC HIS PRO PHE HIS STA LEU PHE 0.579268 0.84
3 BOC HIS PRO PHE HIS LOV ILE HIS 0.554286 0.826667
4 BOC HIS PRO PHE ALA LOV ILE HIS 0.502732 0.826667
5 DHI PRO PHE HIS LEU LEU VAL TYR 0.5 0.885714
6 SER LEU PHE HIS 22G THR PRO 0.472527 0.890411
7 PHE LEU PRO HIS ALY TYR ASP VAL LYS LEU 0.468085 0.914286
8 IVA HIS PRO PHE HIS STA LEU PHE 0.460123 0.788732
9 ARG LEU TYR HIS SEP LEU PRO ALA 0.438503 0.802469
10 PRO PRO THR LEU HIS GLU LEU TYR ASP LEU 0.432432 0.876712
11 TYR PRO ASN VAL ASN ILE HIS ASN PHE 0.431694 0.851351
12 TYR TYR SER ILE ALA PRO HIS SER ILE 0.430168 0.890411
13 ASN TRP SER HIS PRO GLN PHE GLU LYS 0.426829 0.816901
14 ACE PHE HIS PRO ALA NH2 0.426752 0.797101
15 TYR TYR SER ILE ILE PRO HIS SER ILE 0.423729 0.864865
16 LYS TYR TYR SER ILE ILE PRO HIS SER ILE 0.423729 0.864865
17 VAL PRO TYR SER SER ALA GLN NAG 0.416185 0.782051
18 HIS SER LEU PHE HIS PUK THR PRO 0.415789 0.863014
19 PHE ALA PRO GLY PHE PHE PRO TYR LEU 0.41573 0.885714
20 HIS SER ILE THR TYR LEU LEU PRO VAL 0.413978 0.864865
21 PRO HIS PRO PHE HIS LAV ILE HIS LYS 0.413613 0.828571
22 VAL TYR PRO IAS HIS ALA 0.412791 0.847222
23 SER ILE TYR PHE TPO PRO GLU LEU TYR ASP 0.412371 0.7875
24 PRO HIS PRO PHE HIS STA VAL ILE HIS LYS 0.409091 0.777778
25 TYR PRO PHE PHE NH2 0.407895 0.782609
26 DVA DPR GLY DSN DGN DHI DTY DAS DSN 0.405405 0.876712
27 ALA ARG SER HIS SEP TYR PRO ALA 0.403141 0.768293
28 HIS PRO PHE 0.401316 0.742857
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1SMR; Ligand: PIV HIS PRO PHE HIS LPL TYR TYR SER; Similar sites found with APoc: 137
This union binding pocket(no: 1) in the query (biounit: 1smr.bio9) has 36 residues
No: Leader PDB Ligand Sequence Similarity
1 6E08 NAP 1.19403
2 3KVY URA 1.2945
3 1Z6K OAA 1.36519
4 4Q6R SIN 1.49254
5 2II3 CAO 1.52672
6 1ZTH ADP 1.93798
7 1ZP9 ATP 1.93798
8 4RDL FUC GAL NDG FUC 1.94805
9 3FSM 2NC 1.97044
10 3KA2 2NC 1.97044
11 3B8Y ADA ADA ADA ADA 2.08955
12 4OFJ HIS 2.08955
13 1CZA GLC 2.08955
14 2JGV ADP 2.12121
15 1U0A BGC BGC BGC BGC 2.33645
16 1EWK GLU 2.38806
17 4DO1 ANN 2.38806
18 4U5I BXP 2.38806
19 4Q5M ROC 2.46305
20 3PPQ CHT 2.57235
21 3NJQ NJQ 2.59067
22 4WOE 3S5 2.68657
23 5O2N FLC 2.98507
24 4M26 AKG 2.98507
25 5UN9 NHT 2.98507
26 5T2Z 017 3.0303
27 1M1B SPV 3.05085
28 3BY9 SIN 3.07692
29 5VX9 FUC GAL NAG GAL BGC 3.10559
30 4RYV ZEA 3.22581
31 1WPQ 13P 3.28358
32 2IZ1 ATR 3.28358
33 1TV5 A26 3.28358
34 3WRB GDE 3.28358
35 1R4W GSH 3.28358
36 5Y3N 8MF 3.58209
37 6EWZ APC 3.58209
38 1VCO GLN 3.58209
39 2W68 SIA GAL BGC 3.58974
40 4RW3 IPD 3.64238
41 5ME4 HP4 3.64964
42 5H9Q TD2 3.87097
43 5T7I LAT NAG GAL 3.87097
44 5GLT BGC GAL NAG GAL 3.87324
45 2BP1 FLC 3.8806
46 3BOF HCS 3.8806
47 1Q8A HCS 3.8806
48 2RIO ADP 3.8806
49 1OT6 HC4 4
50 5O2J 2PO 4.0293
51 4M8X KGQ 4.0404
52 2ZHL NAG GAL GAL NAG 4.05405
53 2B4B B33 4.09357
54 4WVW SLT 4.16667
55 5W0N UPU 4.1791
56 2Q09 DI6 4.1791
57 5VRH PLM 4.1791
58 3K5X P8D 4.1791
59 3SAO NKN 4.375
60 3UN3 G16 4.47761
61 3GD8 GOL 4.4843
62 3ZXE PGZ 4.51128
63 6GPC ARG 4.7619
64 3G5N PB2 4.77612
65 1IZO PAM 4.77612
66 1GWC GTX 4.78261
67 3KO0 TFP 4.9505
68 1DTL BEP 4.96894
69 2AZC 3TL 5.05051
70 2O4N TPV 5.05051
71 3S43 478 5.05051
72 3U7S 017 5.05051
73 3GGU 017 5.05051
74 4L1A AB1 5.05051
75 2FXD DR7 5.05051
76 6C8X BVR 5.05051
77 2P3C 3TL 5.05051
78 4NJS G08 5.05051
79 4NPT 017 5.05051
80 2YJP CYS 5.15464
81 4PVR ASP 5.16129
82 2BHW XAT 5.17241
83 3NWQ 2NC 5.67164
84 1CEB AMH 5.68182
85 5JVB 2PO 5.71429
86 3OG9 MLT 5.74163
87 5J3R GSH 5.91133
88 5GQX GLC GLC GLC GLC 5.97015
89 1H8P PC 6.42202
90 4XCB AKG 6.51341
91 1FMB HYB 6.73077
92 1W0O SIA 6.86567
93 1VEM GLC GLC 6.86567
94 4ZLA BES 6.86567
95 3B1Q NOS 7.05521
96 6FIV 3TL 7.07965
97 2YJD YJD 7.08333
98 4CUB GAL NAG 7.10383
99 5M7S NHT 7.46269
100 6CED EYA 7.47664
101 3SM2 478 7.57576
102 1WB4 SXX 7.74411
103 4YLZ LAT NAG GAL 7.84314
104 3MWS 017 8.08081
105 1SIV PSI 8.08081
106 1P0Z FLC 8.39695
107 1OFZ FUL 8.65385
108 1OFZ FUC 8.65385
109 1BAI 0Q4 8.87097
110 3EW2 BTN 8.88889
111 4YHQ G10 9.09091
112 3L4N GSH 9.44882
113 3WSJ MK1 9.48276
114 3B00 16A 9.55882
115 4Z28 BTN 9.70149
116 4TR1 GSH 9.78261
117 2BOS GLA GAL 10.2941
118 4O1P ANP 10.4478
119 4GK9 MAN BMA MAN MAN MAN 10.7527
120 4BWL MN9 10.8553
121 1IDA 0PO 12.1212
122 2P3B 3TL 13.1313
123 5G1X ADP 14.2857
124 2Z77 HE7 14.3885
125 3T3C 017 16.1616
126 5FU3 BGC BGC BGC 16.9811
127 4FHT DHB 20.3822
128 3TUR DGL 20.9059
129 5IDB BMA 24.6479
130 2QL9 CIT 26.8041
131 1J71 THR ILE THR SER 44.3114
132 4GID 0GH 45.3731
133 6EJ2 B7E 45.3731
134 3ZLQ 6T9 45.9701
135 3ZKI WZV 45.9701
136 4ZL4 4PK 46.2687
137 3ZKN WZV 47.7612
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