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Receptor
PDB id Resolution Class Description Source Keywords
1SVM 1.94 Å NON-ENZYME: TOXIN_VIRAL CO-CRYSTAL STRUCTURE OF SV40 LARGE T ANTIGEN HELICASE DOMAIN AND ATP SIMIAN VIRUS 40 AAA+ FOLD VIRAL PROTEIN
Ref.: MECHANISMS OF CONFORMATIONAL CHANGE FOR A REPLICATIVE HEXAMERIC HELICASE OF SV40 LARGE TUMOR ANTIGEN. CELL(CAMBRIDGE,MASS.) V. 119 47 2004
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ATP A:800;
B:800;
C:800;
D:800;
E:800;
F:800;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
none;
none;
submit data
507.181 C10 H16 N5 O13 P3 c1nc(...
MG A:750;
B:750;
C:750;
D:750;
E:750;
F:750;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
none;
none;
none;
none;
none;
none;
submit data
24.305 Mg [Mg+2...
ZN A:700;
B:700;
C:700;
D:700;
E:700;
F:700;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
none;
none;
none;
none;
none;
none;
submit data
65.409 Zn [Zn+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1SVM 1.94 Å NON-ENZYME: TOXIN_VIRAL CO-CRYSTAL STRUCTURE OF SV40 LARGE T ANTIGEN HELICASE DOMAIN AND ATP SIMIAN VIRUS 40 AAA+ FOLD VIRAL PROTEIN
Ref.: MECHANISMS OF CONFORMATIONAL CHANGE FOR A REPLICATIVE HEXAMERIC HELICASE OF SV40 LARGE TUMOR ANTIGEN. CELL(CAMBRIDGE,MASS.) V. 119 47 2004
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 62 families.
1 1SVM - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
2 1SVL - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
70% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 43 families.
1 5J47 ic50 = 4.9 uM 6JJ C15 H10 N4 O S c1ccc(cc1)....
2 1SVM - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
3 1SVL - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
50% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 35 families.
1 5J47 ic50 = 4.9 uM 6JJ C15 H10 N4 O S c1ccc(cc1)....
2 1SVM - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
3 1SVL - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ATP; Similar ligands found: 422
No: Ligand ECFP6 Tc MDL keys Tc
1 HEJ 1 1
2 ATP 1 1
3 5FA 0.985507 1
4 AQP 0.985507 1
5 AP5 0.927536 0.971831
6 B4P 0.927536 0.971831
7 BA3 0.913043 0.971831
8 ADP 0.9 1
9 A2D 0.884058 0.971831
10 AGS 0.84 0.945946
11 SAP 0.84 0.945946
12 6YZ 0.833333 0.972222
13 AT4 0.810811 0.958904
14 AN2 0.810811 0.985915
15 25L 0.809524 0.985915
16 AR6 0.802632 0.971831
17 APR 0.802632 0.971831
18 M33 0.8 0.958333
19 ACQ 0.794872 0.972222
20 TAT 0.794872 0.958904
21 T99 0.794872 0.958904
22 AD9 0.792208 0.972222
23 ACP 0.789474 0.972222
24 AMP 0.788732 0.971429
25 A 0.788732 0.971429
26 ANP 0.772152 0.972222
27 CA0 0.753247 0.945205
28 ADX 0.753247 0.873418
29 A22 0.746988 0.985915
30 50T 0.74359 0.958333
31 PRX 0.734177 0.893333
32 APC 0.734177 0.958904
33 ABM 0.733333 0.917808
34 ATF 0.731707 0.958904
35 ITT 0.730769 0.943662
36 7D4 0.730769 0.905405
37 ADQ 0.729412 0.945205
38 A3R 0.729412 0.907895
39 AP2 0.714286 0.958904
40 A12 0.714286 0.958904
41 A1R 0.709302 0.907895
42 SRA 0.706667 0.918919
43 5AL 0.698795 0.931507
44 HFD 0.695122 0.945946
45 9X8 0.693182 0.92
46 OAD 0.693182 0.945205
47 AU1 0.6875 0.972222
48 SRP 0.682353 0.906667
49 G5P 0.680851 0.921053
50 25A 0.678161 0.971831
51 3OD 0.677778 0.945205
52 4AD 0.670455 0.92
53 G3A 0.670213 0.921053
54 00A 0.662921 0.883117
55 RBY 0.662651 0.932432
56 ADP PO3 0.662651 0.943662
57 ADV 0.662651 0.932432
58 BIS 0.659341 0.933333
59 8QN 0.659091 0.931507
60 5SV 0.659091 0.848101
61 OOB 0.659091 0.931507
62 GTA 0.65625 0.886076
63 UP5 0.653061 0.92
64 AMO 0.651685 0.932432
65 PAJ 0.651685 0.884615
66 2A5 0.650602 0.918919
67 MAP 0.647727 0.945946
68 3AT 0.647059 0.971831
69 AHX 0.644444 0.896104
70 DLL 0.644444 0.931507
71 ATR 0.642857 0.971429
72 PAP 0.642857 0.985714
73 PTJ 0.641304 0.896104
74 7D3 0.6375 0.905405
75 3UK 0.637363 0.918919
76 SON 0.634146 0.932432
77 A4P 0.633663 0.843373
78 ALF ADP 0.632184 0.87013
79 ADP ALF 0.632184 0.87013
80 PR8 0.630435 0.85
81 WAQ 0.630435 0.883117
82 LAD 0.630435 0.860759
83 B5V 0.630435 0.906667
84 AFH 0.628866 0.884615
85 LMS 0.628205 0.82716
86 GAP 0.627907 0.893333
87 DTP 0.627907 0.905405
88 VO4 ADP 0.625 0.931507
89 ADP VO4 0.625 0.931507
90 TXA 0.623656 0.932432
91 ME8 0.623656 0.839506
92 1ZZ 0.623656 0.839506
93 NB8 0.623656 0.896104
94 FYA 0.623656 0.905405
95 DQV 0.622449 0.958333
96 T5A 0.621359 0.841463
97 ADN 0.619718 0.84507
98 RAB 0.619718 0.84507
99 XYA 0.619718 0.84507
100 DAL AMP 0.611111 0.905405
101 9SN 0.610526 0.871795
102 48N 0.61 0.896104
103 AP0 0.607843 0.896104
104 9ZD 0.604396 0.907895
105 9ZA 0.604396 0.907895
106 FA5 0.604167 0.906667
107 B5M 0.604167 0.894737
108 YAP 0.604167 0.894737
109 B5Y 0.604167 0.894737
110 NAI 0.60396 0.907895
111 6V0 0.60396 0.896104
112 TXD 0.60396 0.907895
113 DND 0.60396 0.932432
114 NXX 0.60396 0.932432
115 NAX 0.60396 0.873418
116 ADP BMA 0.602151 0.918919
117 A2R 0.6 0.985915
118 OMR 0.598039 0.851852
119 TXE 0.598039 0.907895
120 XAH 0.597938 0.839506
121 7DT 0.593023 0.985714
122 AOC 0.592593 0.821918
123 4UV 0.591837 0.894737
124 DDS 0.590909 0.878378
125 139 0.590476 0.873418
126 CNA 0.584906 0.932432
127 6AD 0.58427 0.909091
128 5AS 0.583333 0.77907
129 5N5 0.581081 0.819444
130 GA7 0.58 0.906667
131 4UU 0.58 0.894737
132 4TC 0.576923 0.896104
133 ADJ 0.575472 0.851852
134 5CD 0.573333 0.805556
135 A4D 0.573333 0.819444
136 RGT 0.571429 0.958904
137 A3P 0.571429 0.971429
138 7D5 0.56962 0.878378
139 LAQ 0.568627 0.839506
140 F2R 0.564815 0.864198
141 80F 0.563636 0.841463
142 YLP 0.563107 0.819277
143 A A 0.5625 0.944444
144 UPA 0.561905 0.907895
145 AV2 0.56044 0.917808
146 COD 0.559633 0.811765
147 4UW 0.557692 0.860759
148 JB6 0.556701 0.883117
149 3AM 0.555556 0.929577
150 ATP A A A 0.555556 0.930556
151 A2P 0.552941 0.957143
152 TYM 0.552381 0.906667
153 NA7 0.552083 0.958904
154 EP4 0.551282 0.753247
155 MYR AMP 0.55102 0.817073
156 PPS 0.549451 0.873418
157 YLC 0.54717 0.839506
158 YLB 0.54717 0.819277
159 NAD 0.545455 0.931507
160 DAT 0.545455 0.905405
161 TYR AMP 0.544554 0.87013
162 G5A 0.544444 0.77907
163 M2T 0.544304 0.734177
164 DTA 0.544304 0.786667
165 3DH 0.54321 0.773333
166 128 0.542857 0.776471
167 AHZ 0.538462 0.817073
168 GTP 0.537634 0.92
169 SSA 0.537634 0.8
170 MTA 0.5375 0.773333
171 IOT 0.537037 0.831325
172 A3D 0.535714 0.918919
173 ARG AMP 0.533981 0.829268
174 7MD 0.533981 0.8625
175 AR6 AR6 0.533981 0.917808
176 YLA 0.53211 0.819277
177 AMP DBH 0.529412 0.893333
178 IMO 0.529412 0.929577
179 TAD 0.528846 0.884615
180 AYB 0.527273 0.809524
181 A5A 0.526882 0.807229
182 HDV 0.526882 0.893333
183 TSB 0.526316 0.819277
184 EAD 0.525424 0.873418
185 2AM 0.52439 0.943662
186 6RE 0.52381 0.759494
187 7DD 0.522727 0.985714
188 V3L 0.521739 0.971831
189 AVV 0.520833 0.896104
190 BTX 0.517857 0.841463
191 NAE 0.517241 0.894737
192 52H 0.515789 0.77907
193 54H 0.515789 0.788235
194 VMS 0.515789 0.788235
195 NSS 0.515464 0.8
196 BT5 0.513274 0.831325
197 NAQ 0.512821 0.871795
198 ZAS 0.511905 0.766234
199 J7C 0.511628 0.769231
200 A3N 0.511628 0.786667
201 5X8 0.511111 0.763158
202 53H 0.510417 0.77907
203 8X1 0.510417 0.752809
204 5CA 0.510417 0.8
205 NVA LMS 0.510204 0.752809
206 ARU 0.510204 0.860759
207 AF3 ADP 3PG 0.509259 0.8375
208 ZID 0.508475 0.918919
209 P1H 0.508197 0.851852
210 OVE 0.505882 0.905405
211 S4M 0.505747 0.666667
212 LEU LMS 0.50505 0.752809
213 LPA AMP 0.504673 0.817073
214 7MC 0.504587 0.841463
215 DZD 0.5 0.884615
216 FB0 0.5 0.804598
217 MAO 0.5 0.759036
218 DSZ 0.5 0.8
219 LSS 0.5 0.761364
220 DSH 0.5 0.725
221 P5A 0.5 0.744444
222 NDE 0.495935 0.932432
223 N0B 0.495798 0.819277
224 M24 0.495726 0.85
225 YLY 0.495726 0.809524
226 NJP 0.495575 0.945946
227 9K8 0.49505 0.714286
228 MGP 0.494737 0.884615
229 6C6 0.494624 0.881579
230 NAJ PZO 0.491379 0.848101
231 0WD 0.491228 0.921053
232 6G0 0.489583 0.884615
233 GJV 0.488636 0.75
234 6FA 0.488189 0.841463
235 5AD 0.486842 0.746479
236 KAA 0.485149 0.752809
237 GSU 0.485149 0.77907
238 71V 0.483146 0.907895
239 NEC 0.482759 0.746667
240 A3G 0.482759 0.8
241 ODP 0.482456 0.909091
242 FAS 0.48062 0.851852
243 FAD 0.48062 0.851852
244 7D7 0.480519 0.743243
245 FDA 0.480315 0.833333
246 N6P 0.48 0.915493
247 2SA 0.479167 0.932432
248 GP3 0.478723 0.921053
249 4TA 0.478261 0.807229
250 SFG 0.478261 0.75
251 G A A A 0.478261 0.871795
252 AMP NAD 0.478261 0.905405
253 NPW 0.477876 0.886076
254 NDP 0.477876 0.921053
255 NDC 0.47619 0.871795
256 YSA 0.47619 0.77907
257 NAJ PYZ 0.475 0.807229
258 MGO 0.474227 0.860759
259 GDP 0.473684 0.92
260 NZQ 0.473684 0.909091
261 TXP 0.473684 0.921053
262 6IA 0.473684 0.8375
263 A7D 0.472527 0.776316
264 SFD 0.469231 0.734043
265 A5D 0.468085 0.786667
266 SA8 0.468085 0.707317
267 ZDA 0.468085 0.864865
268 12D 0.46789 0.785714
269 PGS 0.467391 0.883117
270 MHZ 0.467391 0.697674
271 8PZ 0.466667 0.8
272 62F 0.466165 0.8625
273 DA 0.465909 0.878378
274 D5M 0.465909 0.878378
275 GGZ 0.464646 0.825
276 SAH 0.463158 0.74359
277 SAI 0.463158 0.734177
278 FAY 0.462687 0.8625
279 Y3J 0.4625 0.726027
280 PO4 PO4 A A A A PO4 0.460784 0.902778
281 AAM 0.460674 0.971429
282 RFL 0.459259 0.821429
283 SMM 0.459184 0.686047
284 HF7 0.459184 0.893333
285 AMZ 0.458824 0.916667
286 C2R 0.458824 0.90411
287 SAM 0.458333 0.690476
288 A3S 0.456522 0.810811
289 FNK 0.455224 0.804598
290 U A 0.453782 0.907895
291 7C5 0.453704 0.818182
292 EEM 0.453608 0.690476
293 AAT 0.453608 0.707317
294 XNP 0.452991 0.873418
295 A G 0.452991 0.883117
296 PRT 0.45283 0.931507
297 AIR 0.451219 0.901408
298 62X 0.45098 0.666667
299 DCA 0.45 0.823529
300 ETB 0.45 0.833333
301 GSP 0.45 0.873418
302 U A G G 0.449153 0.883117
303 NIA 0.448276 0.822785
304 A3T 0.446809 0.821918
305 A A A 0.446602 0.905405
306 K15 0.446602 0.682353
307 PUA 0.446281 0.884615
308 6K6 0.445545 0.930556
309 GEK 0.445545 0.7375
310 4YB 0.445455 0.761364
311 S7M 0.444444 0.690476
312 Z5A 0.443548 0.77907
313 1DG 0.443548 0.921053
314 DG1 0.443548 0.921053
315 0T1 0.442623 0.823529
316 COA 0.442623 0.823529
317 WSA 0.442478 0.788235
318 8BR 0.43956 0.906667
319 8Q2 0.438596 0.772727
320 101 0.438202 0.878378
321 IDP 0.4375 0.918919
322 NVA 2AD 0.4375 0.759494
323 9JJ 0.435714 0.8625
324 NAP 0.435484 0.945205
325 APU 0.434783 0.894737
326 A U 0.434783 0.87013
327 7RP 0.433333 0.928571
328 A6D 0.432692 0.722892
329 AMX 0.432 0.833333
330 J7V 0.432 0.833333
331 TAP 0.432 0.907895
332 COS 0.432 0.804598
333 CAO 0.432 0.795455
334 30N 0.432 0.752688
335 V1N 0.431193 0.917808
336 649 0.429825 0.744444
337 P5F 0.429577 0.823529
338 NA0 0.428571 0.932432
339 SCO 0.428571 0.823529
340 CMX 0.428571 0.823529
341 7RA 0.428571 0.957747
342 0UM 0.427184 0.698795
343 GAV 0.427184 0.884615
344 QQY 0.426966 0.815789
345 1RB 0.426966 0.885714
346 ACK 0.426966 0.861111
347 G1R 0.425743 0.907895
348 GCP 0.425743 0.896104
349 FAM 0.425197 0.804598
350 FCX 0.425197 0.795455
351 ACO 0.425197 0.795455
352 GNH 0.424242 0.907895
353 F2N 0.423611 0.813953
354 GKE 0.422018 0.884615
355 GDD 0.422018 0.884615
356 GDC 0.422018 0.884615
357 HAX 0.421875 0.804598
358 3AD 0.421687 0.805556
359 9GM 0.421569 0.896104
360 GNP 0.421569 0.896104
361 FA9 0.42069 0.864198
362 TM1 0.420561 0.77381
363 KB1 0.420561 0.698795
364 H6Y 0.42 0.945205
365 2MC 0.419847 0.769231
366 3KK 0.418605 0.804598
367 FYN 0.418605 0.823529
368 S8M 0.417476 0.759494
369 7L1 0.417323 0.795455
370 2VA 0.416667 0.8
371 26A 0.416667 0.763158
372 NHD 0.416667 0.905405
373 QQX 0.41573 0.805195
374 CA6 0.415385 0.729167
375 OXK 0.415385 0.804598
376 COK 0.415385 0.804598
377 SOP 0.415385 0.804598
378 MCD 0.415385 0.804598
379 YE1 0.413534 0.813953
380 RMB 0.413043 0.873239
381 FAI 0.413043 0.916667
382 AS 0.413043 0.833333
383 CO6 0.412214 0.804598
384 1VU 0.412214 0.795455
385 CMC 0.412214 0.804598
386 NMX 0.412214 0.76087
387 SXZ 0.411215 0.710843
388 ANZ 0.410714 0.8
389 SCA 0.410448 0.804598
390 CAJ 0.409091 0.804598
391 SCD 0.409091 0.823529
392 EO7 0.408602 0.788235
393 D3Y 0.407767 0.789474
394 CC5 0.407407 0.816901
395 KH3 0.40708 0.674419
396 A C A C 0.406504 0.848101
397 SLU 0.406504 0.770115
398 G 0.40625 0.906667
399 5GP 0.40625 0.906667
400 A1S 0.406015 0.804598
401 IVC 0.406015 0.813953
402 MLC 0.406015 0.804598
403 3HC 0.406015 0.813953
404 1HE 0.406015 0.786517
405 BCO 0.406015 0.804598
406 GTG 0.405405 0.886076
407 NMN AMP PO4 0.404959 0.87013
408 3D1 0.404762 0.773333
409 3L1 0.404762 0.773333
410 2BA 0.404255 0.915493
411 CMP 0.404255 0.901408
412 VRT 0.40404 0.769231
413 SO8 0.40404 0.789474
414 MCA 0.402985 0.795455
415 COO 0.402985 0.804598
416 CAA 0.402985 0.813953
417 3NZ 0.401869 0.782051
418 G2R 0.401869 0.884615
419 ZZB 0.4 0.77381
420 2FA 0.4 0.813333
421 MC4 0.4 0.76087
422 2CP 0.4 0.795455
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1SVM; Ligand: ATP; Similar sites found with APoc: 633
This union binding pocket(no: 1) in the query (biounit: 1svm.bio1) has 25 residues
No: Leader PDB Ligand Sequence Similarity
1 3Q72 GNP None
2 1G16 GDP None
3 1R2Q GNP None
4 1TU3 GNP None
5 6G14 G4P 1.02041
6 1SVK ALF GDP 1.13314
7 1F9V ADP 1.15274
8 1Y3A GDP 1.21581
9 2OM2 GDP 1.23077
10 1TAD ALF 1.23457
11 1TAD GDP 1.23457
12 1BH2 GSP 1.26984
13 3OUM TOF 1.2931
14 3ESS 18N 1.30435
15 2WHX ADP 1.32626
16 4FRZ ADP 1.32626
17 2JLR ANP 1.32626
18 5LB3 ADP 1.32626
19 1RRC ADP 1.3289
20 3COB ADP 1.35501
21 4H1V GNP 1.35501
22 4LC1 GDP 1.48368
23 2NCD ADP 1.59151
24 4HSE ADP 1.59151
25 3TBK ANP 1.59151
26 1MH1 GNP 1.6129
27 1M7B GTP 1.63043
28 3R7F CP 1.64474
29 2OBM ADP 1.72911
30 5H4S RAM 1.76056
31 1EK0 GNP 1.76471
32 1KAO GDP 1.79641
33 1BG2 ADP 1.84615
34 1D5C GDP 1.85185
35 3FB4 AP5 1.85185
36 2DPY ADP 1.85676
37 1FNN ADP 1.85676
38 4R43 GDP 1.85676
39 4RD0 GDP 1.85676
40 1K6M AGS 1.85676
41 2OG2 MLI 1.94986
42 3BPX SAL 2.02703
43 2ZPT A3P 2.0339
44 1FQK GDP 2.04082
45 3B5J 12D 2.05761
46 5VGR GDP 2.08817
47 5FG3 GDP 2.12202
48 1G7S GDP 2.12202
49 1W5T ANP 2.12202
50 1G4U GDP 2.12202
51 1W5T ADP 2.12202
52 2B8W ALF 5GP 2.13415
53 3B7G ANP 2.17391
54 3FYH ADP 2.17391
55 2J5V PCA 2.17984
56 4O08 PO6 2.18069
57 2HK9 ATR 2.18182
58 5YT0 GDP 2.1978
59 5UIV ADP 2.20264
60 2FNA ADP 2.2409
61 3MD0 GDP 2.25352
62 4QOS ADP 2.26415
63 3B9Q MLI 2.31788
64 2XT3 ADP 2.32558
65 2OZE AGS 2.34899
66 6A20 ADP 2.38727
67 4DCT GDP 2.38727
68 6B4K ANP 2.38727
69 4KVA GTP 2.38727
70 2BIF SIN 2.38727
71 2BIF ANP 2.38727
72 1OS1 ATP 2.38727
73 1OS1 PYR 2.38727
74 3FIU POP 2.40964
75 4E03 ADP 2.42718
76 1PUJ GNP 2.48227
77 2EW1 GNP 2.48756
78 5CK5 GDP 2.53165
79 2I6U CP 2.60586
80 5L3W GDP 2.61438
81 4HUT ATP 2.6178
82 2GDJ ANP 2.65152
83 1KK1 GNP 2.65252
84 1SKQ GDP 2.65252
85 4YJ1 ADP 2.65252
86 1XKV ATP 2.65252
87 5IRN ADP 2.65252
88 5FHD ADP ALF 2.65252
89 3RC3 ANP 2.65252
90 5FTB ANP 2.65252
91 1LVK MNT BEF 2.65252
92 1ZD9 GDP 2.65957
93 2Z5F A3P 2.68456
94 1P72 ADP 2.69461
95 6EK3 OUL 2.71493
96 1E2K TMC 2.71903
97 1VHT BA3 2.75229
98 3KJI ADP 2.75591
99 6AIC AMP 2.80374
100 6B8B ADP 2.81124
101 1OXV ANP 2.83286
102 3VPD BUA 2.84698
103 1T5C ADP 2.86533
104 3FWY ADP 2.86624
105 1Z0A GDP 2.87356
106 3U6B GDP 2.91777
107 1D8T GDP 2.91777
108 5JBQ GDP 2.91777
109 4G5G GDP 2.91777
110 3U6K GDP 2.91777
111 5LTJ ADP 2.91777
112 2CE7 ADP 2.91777
113 5H7K GDP 2.91777
114 2BVN GNP 2.91777
115 5LTJ BEF 2.91777
116 5AK0 8V1 2.91777
117 2BCG GDP 2.91777
118 2ZPA ADP 2.91777
119 5HV7 RBL 2.91777
120 1GWN GTP 2.92683
121 5H68 AGS 2.94118
122 1BO4 COA 2.97619
123 1IN4 ADP 2.99401
124 2WIC GNP 2.99625
125 3TKL GTP 3.06122
126 3FVQ ATP 3.06407
127 3A4M ADP 3.07692
128 3EWA ANP 3.10559
129 5EP2 AZU 3.125
130 3MBI HSX 3.13589
131 2A5J GDP 3.14136
132 1OIV GDP 3.14136
133 5LX6 78P 3.14136
134 1OIX GDP 3.14136
135 1UJ2 C5P 3.1746
136 1UJ2 ADP 3.1746
137 4AG5 ADP 3.18302
138 1MKY GDP 3.18302
139 1R6B ADP 3.18302
140 3E70 GDP 3.18302
141 1WDT GTP 3.18302
142 4XGU ADP 3.18302
143 5HR5 ADP 3.18302
144 2FAH GDP 3.18302
145 3CV2 OXL 3.18302
146 2O0J ADP 3.18302
147 5ZBR ANP 3.2
148 4LJ9 ACP 3.24484
149 3DZD ADP 3.26087
150 4LPS GDP 3.30579
151 3SFV GDP 3.31492
152 3BFV ADP 3.32103
153 1WF3 GNP 3.32226
154 1G6O ADP 3.33333
155 3T34 GDP 3.33333
156 2Y8E GNP 3.35196
157 5NM7 GLY 3.38346
158 1NST A3P 3.38462
159 2ORV 4TA 3.4188
160 3NKV GNP 3.42857
161 2AWN ADP 3.44828
162 4J0Q GDP 3.44828
163 4IEE AGS 3.44828
164 1W0J ADP 3.44828
165 5Y6N ADP 3.44828
166 5WC2 ADP 3.44828
167 1G41 ADP 3.44828
168 4A4Z ANP 3.44828
169 5N69 ADP 3.44828
170 4NCN GTP 3.44828
171 1W0J ADP BEF 3.44828
172 5JCP GDP ALF 3.44828
173 4OHY ANP 3.44828
174 1NY5 ADP 3.44828
175 2ZJ5 ADP 3.44828
176 3WYF GTP 3.44828
177 6DEF GCP 3.44828
178 1F5N GNP 3.44828
179 4C4P GNP 3.46821
180 1R0X ATP 3.4965
181 5DI9 GNP 3.4965
182 5UWS GNP 3.4965
183 5UWJ GNP 3.4965
184 5UWI GNP 3.4965
185 5DIF GNP 3.4965
186 5UWW GNP 3.4965
187 5UWU GNP 3.4965
188 5DHF GNP 3.4965
189 5UWO GNP 3.4965
190 1G6H ADP 3.50195
191 3IUY AMP 3.50877
192 5WDR GNP 3.50877
193 4FCW ADP 3.53698
194 3ITJ CIT 3.5503
195 5G41 AP5 3.58744
196 5M04 GDP 3.61111
197 3GJ0 GDP 3.61991
198 3GJ4 GDP 3.61991
199 3GJ5 GDP 3.61991
200 3GJ8 GDP 3.61991
201 3VX3 ADP 3.62903
202 2RCN GDP 3.63128
203 2CJW GDP 3.64583
204 3M1I GTP 3.66492
205 3N5C GDP 3.7037
206 2X77 GDP 3.7037
207 5MVR ADP 3.7037
208 5BXQ GDP 3.7037
209 1H65 GDP 3.7037
210 1IBR GNP 3.7037
211 1YQT ADP 3.71353
212 5YV5 ADP 3.71353
213 5TSH ANP 3.71353
214 5TSH ADP 3.71353
215 5W76 GDP 3.71353
216 4IHQ ADP 3.71353
217 1Z6T ADP 3.71353
218 5M7P ADP 3.71353
219 2VVG ADP 3.71429
220 3BOS CDP 3.71901
221 5W7Q GDP 3.75335
222 4TMZ GSP 3.76812
223 2ZEJ GDP 3.80435
224 2VOH CIT 3.82166
225 4KBF AMP 3.83562
226 2EFE GNH 3.8674
227 4FK7 P34 3.93013
228 2GKS ADP 3.97878
229 1DAR GDP 3.97878
230 2C9O ADP 3.97878
231 3FKQ ATP 3.97878
232 2HT6 GDP 4.02299
233 3RLF ANP 4.05405
234 3EC1 GDP 4.06504
235 3DKP ADP 4.08163
236 2ZFI ADP 4.09836
237 2ZX2 RAM 4.10256
238 1W4R TTP 4.10256
239 2A5F GTP 4.14508
240 3DEF GDP 4.19847
241 1VKJ A3P 4.21053
242 5J1J ANP 4.21053
243 5IRR GSP 4.22078
244 1GP2 GDP 4.22535
245 2OFE NAG 4.22535
246 4Z2S NDG 4.22535
247 4Z2S NAG 4.22535
248 4AG9 COA 4.24242
249 1D2E GDP 4.24403
250 5H7J GCP 4.24403
251 5XDR ADP 4.24403
252 3HU3 AGS 4.24403
253 2XAU ADP 4.24403
254 6C90 ADP 4.24403
255 2C77 GNP 4.24403
256 2C78 GNP 4.24403
257 5MZN ADP 4.24403
258 1X6V ADP 4.24403
259 1ZJ6 G3D 4.27807
260 1VG0 GDP 4.34783
261 4KAX GTP 4.34783
262 1VG8 GNP 4.34783
263 1GXU 2HP 4.3956
264 1MR3 G3D 4.41989
265 4P4T GDP 4.44444
266 4U5X GNP 4.49438
267 2IYL GDP 4.50928
268 2FSH ANP 4.50928
269 5E5U MLI 4.52261
270 4BAS GNP 4.52261
271 3T1O GDP 4.54545
272 4BQS ADP 4.54545
273 4BQS K2Q 4.54545
274 5XC5 GTP 4.54545
275 3NHB ADP 4.57516
276 4LHW GNP 4.5977
277 3TNF GNP 4.5977
278 3QBT GNP 4.5977
279 4YLG GDP 4.62428
280 3REF GDP 4.63918
281 4TTQ ATP 4.65116
282 4V03 ADP 4.66926
283 4X8O AP5 4.6729
284 3DOE GTP 4.6875
285 4LX0 BEF GDP 4.77454
286 4PX9 ADP 4.79452
287 2A9K GDP 4.81283
288 1FP6 ADP 4.84429
289 4M9Q GNP 4.84582
290 1VG1 GDP 4.86486
291 1VG9 GDP 4.86486
292 5G3Y ADP 4.86726
293 2HF9 GSP 4.86726
294 2B8T THM 4.93274
295 5KSZ GCP 4.95283
296 2QZ4 ADP 4.96183
297 4HDO GNP 4.96894
298 4HAT GNP 5
299 5XKT GNP 5
300 4HI0 GDP 5.02513
301 2F9L GDP 5.02513
302 2QG6 NMN 5.02513
303 2IS6 ADP 5.03979
304 4ZKD GDP 5.03979
305 4MKG AP5 5.06912
306 1GOJ ADP 5.07042
307 4WZA ADP 5.07246
308 4WZA ACP 5.07246
309 5OEC GDP 5.07614
310 5O74 GDP 5.07614
311 3BC1 GNP 5.08475
312 4NE2 ADP 5.08982
313 4NE2 SH2 5.08982
314 5Z2M GTP 5.11364
315 3ZFD ANP 5.12821
316 5GVR LMR 5.12821
317 5X40 ACP 5.13699
318 1UAD GNP 5.14286
319 4JLV ADP 5.20446
320 1M7G AV2 5.21327
321 1M7G ADX 5.21327
322 1M7G ADP 5.21327
323 3LQV ADE 5.21739
324 5SZH GNP 5.22876
325 1XX6 ADP 5.2356
326 4ZI2 GNP 5.26316
327 1M2O GNP 5.26316
328 3WYG GTP 5.26316
329 4GOJ GNP 5.29101
330 5W75 GDP 5.30504
331 5Z69 AGS 5.30504
332 1YTM ATP 5.30504
333 6FAA ADP 5.30504
334 1JJV ATP 5.33981
335 1U8Z GDP 5.35714
336 3Q9L ATP 5.38462
337 2Y65 ADP 5.47945
338 4P3Y GDP 5.49451
339 2PL3 ADP 5.50847
340 1SQ5 ADP 5.51948
341 1FZQ GDP 5.52486
342 1F6B GDP 5.55556
343 4LYA ATP 5.57029
344 3WXM GTP 5.57029
345 3VMF GTP 5.57029
346 1OYY AGS 5.57029
347 5LOL GSH 5.5814
348 6BSX E7S 5.61798
349 6BSX GDP 5.61798
350 5L3R GCP 5.64784
351 1S8F GDP 5.64972
352 4PC3 GDP 5.67376
353 4IJ6 SEP 5.6872
354 5J1S ATP 5.69106
355 1OW3 GDP 5.69948
356 4WEI GLC GAL 5.77617
357 2RGX AP5 5.82524
358 5I0H ADP BEF 5.83554
359 3EZ2 ADP 5.83554
360 4ZNL BEF ADP 5.83942
361 4BJX 73B 5.88235
362 5IRC GDP 5.91398
363 2O66 FLC 5.92593
364 4D0N GDP 5.94595
365 5HPY GDP 5.94595
366 6BC0 GSP 5.94595
367 6BCB GSP 5.94595
368 1YZN GNP 5.94595
369 1Z2A GDP 5.95238
370 3AQ4 GDP 5.97826
371 4UXH T5A 5.97826
372 1KMQ GNP 5.97826
373 2D2F ADP 6
374 3TMK T5A 6.01852
375 5L3V GDP 6.02007
376 1O3Y GTP 6.0241
377 1J2J GTP 6.0241
378 5L3S GNP 6.04027
379 5L3S G 6.04027
380 5VOM 9GY 6.04027
381 1CXZ GSP 6.04396
382 1LVG ADP 6.06061
383 3AB3 GDP 6.07735
384 1ZCB GDP 6.07735
385 2GCO GNP 6.1008
386 2GCN GDP 6.1008
387 4XOI GTP 6.11111
388 3GJ7 GDP 6.12245
389 5HCN GCP 6.13027
390 4XSH GSP 6.14525
391 4R2I ANP 6.19048
392 4WZ6 ATP 6.2069
393 2XTZ GSP 6.21469
394 1TX4 ALF GDP 6.21469
395 4YMU ATP 6.25
396 2NGR GDP 6.28272
397 1A4R GNH 6.28272
398 1A4R GDP 6.28272
399 1GRN GDP 6.28272
400 2NGR AF3 6.28272
401 2WMO GTP 6.31579
402 1Z06 GNP 6.34921
403 4ZG4 VO4 ADP 6.36605
404 2GJ8 ALF GDP 6.39535
405 4QM7 GTP 6.43275
406 1Z08 GNP 6.47059
407 1YZQ GNP 6.47059
408 5DI3 GNP 6.48649
409 3CNL GNP 6.48855
410 2WOJ ADP ALF 6.49718
411 3Q85 GNP 6.50888
412 4V0K GDP 6.50888
413 3CX8 GSP 6.50888
414 2QQ0 THM 6.52174
415 2QQ0 ANP 6.52174
416 2QQ0 TMP 6.52174
417 2QQ0 ADP 6.52174
418 4XVU ATP 6.52174
419 2X2T GAL NGA 6.53595
420 1KY3 GDP 6.59341
421 4YC7 GNP 6.62983
422 5JCZ GDP 6.6313
423 2GK6 ADP 6.6313
424 5GOE GDP 6.63507
425 2CHG ANP 6.63717
426 4R98 GNH 6.64207
427 2WCU FUC 6.71141
428 3QKT ANP 6.78466
429 3PCR GTP 6.79012
430 1GOT GDP 6.84932
431 2QEN ADP 6.85714
432 3WY9 GDP 6.89655
433 3WYA GDP 6.89655
434 2W58 ADP 6.93069
435 1G8S MET 6.95652
436 3TK1 GDP 6.9697
437 2BEK ATP 7.00389
438 5K5Z ANP 7.00637
439 1Z0J GTP 7.05882
440 1ZC3 GNP 7.07965
441 1JI0 ATP 7.08333
442 2ODE ALF GDP 7.0922
443 1YVD GNP 7.10059
444 5VHC BEF ADP 7.1618
445 1TQ4 GDP 7.1618
446 3GJX GTP 7.1618
447 3CPJ GDP 7.17489
448 3LN9 FLC 7.19424
449 3IIJ ADP 7.22222
450 4DID GDP 7.23684
451 1RE0 GDP 7.23982
452 1Z0F GDP 7.26257
453 6BCA GSP 7.28477
454 4KVG GTP 7.30769
455 5BQ5 ADP BEF 7.40741
456 4D81 ADP 7.42049
457 4D0G GTP 7.42857
458 5ZB0 TYD 7.57576
459 5ZB0 ADP 7.57576
460 1XMV ADP 7.58427
461 2CBZ ATP 7.59494
462 1NJF AGS 7.6
463 1NJF ADP 7.6
464 3LRE ADP 7.60563
465 1L2T ATP 7.65957
466 3KTA AP5 7.69231
467 2OFW ADX 7.69231
468 1WA5 GTP 7.69231
469 1D8C GLV 7.69231
470 3RAB GNP 7.69231
471 3MJH GTP 7.7381
472 1ZUI SKM 7.7381
473 2WJH GDP 7.83133
474 2WJH FLC 7.83133
475 2PZE ATP 7.86026
476 4YDS ATP 7.89474
477 3T5G GDP 7.89474
478 1KSH GDP 7.89474
479 1XPJ TLA 7.93651
480 2KIN ADP 8
481 3ZQ6 ADP ALF 8.02469
482 3IO3 ADP 8.04598
483 1D2N ANP 8.08823
484 3DC4 ADP 8.13953
485 1Y63 ADP 8.15217
486 5EE5 GTP 8.18713
487 5ZXD ATP 8.22281
488 4PJ3 ANP 8.22281
489 1ZIN AP5 8.29493
490 3W5J GDP 8.33333
491 1IHU ADP 8.48806
492 4Q1A 2XZ 8.48806
493 4Q1A UDP 8.48806
494 1IHU AF3 8.48806
495 6CRK GDP 8.49421
496 1G7C 5GP 8.51064
497 1NF3 GNP 8.59375
498 1RJ9 GCP 8.66667
499 2IL4 COA 8.73786
500 5H67 ATP 8.75
501 1XEX ATP 8.79121
502 1I4D GDP 8.85417
503 2IXE ATP 8.85609
504 4PPF FLC 8.85714
505 1E96 GTP 8.86699
506 2ZR9 DTP 8.88252
507 2J59 GTP 8.92857
508 1XP8 AGS 9.01639
509 5BN3 ADP 9.01857
510 5LEF GTP 9.09091
511 4NU0 AP5 9.21659
512 1S3G AP5 9.21659
513 1JJ7 ADP 9.23077
514 3A1S GDP 9.30233
515 4KFU ACP 9.43396
516 5I8G 69E 9.4697
517 1YZG GDP 9.49721
518 2FJU GSP 9.55056
519 3T12 GDP ALF 9.55882
520 2WJG GDP 9.57447
521 1HE1 GDP 9.65909
522 1HE1 AF3 9.65909
523 3RWO GDP 9.72973
524 3P4X ADP 9.81432
525 6AU6 GDP 9.81432
526 1RYH GNP 9.85222
527 4TL6 ANP 9.88142
528 2D7D ADP 10
529 1OFH ADP 10
530 4L9Z OXL 10.0295
531 5OCG GNP 10.0529
532 5UQW GDP 10.0529
533 4ITR GDP 10.1266
534 4MKF AP5 10.1382
535 5TB5 GDP 10.2703
536 5TAR GDP 10.2703
537 1ION ADP 10.2881
538 1NRJ GTP 10.3448
539 2W2X GSP 10.4839
540 1V8K ANP 10.4878
541 2FFQ GSP 10.5263
542 1G3Q ADP 10.5485
543 4DKX GDP 10.6481
544 2QN6 GDP 10.7527
545 2BME GNP 10.7527
546 3PQC GDP 10.7692
547 2Q8M AMP 10.8434
548 1AKY AP5 10.9091
549 2C5L GTP 10.9827
550 1TL2 NDG 11.0169
551 4B47 GDP 11.0193
552 5KSP GDP 11.0526
553 4K81 GTP 11.1111
554 1CR1 TTP 11.1486
555 5EXT ADP 11.1538
556 5O2T GSP 11.2426
557 5E95 GDP 11.3095
558 1LFD GNP 11.3772
559 5WLB GNP 11.4458
560 2UZI GTP 11.4458
561 1WQ1 AF3 11.4458
562 3CH5 GDP 11.5385
563 1NN5 ANP 11.6279
564 1NN5 2DT 11.6279
565 1DS6 GDP 11.6667
566 1UPT GTP 11.6667
567 5U32 GDP 11.8644
568 4RJD TFP 12.1212
569 4OI4 ATP 12.1739
570 2J0V GDP 12.2642
571 6E8I PTR 12.426
572 3UIE ANP 12.5
573 5C2N NAG 12.5
574 3H4S ADP 12.5926
575 1HTW ADP 12.6582
576 4HE2 AMP 12.7219
577 1CS4 GSP 12.7358
578 1S9D GDP 12.8079
579 3LXR GDP 13.0208
580 4NON GDP 13.0769
581 4U00 ADP 13.1148
582 1KO8 6PG 13.1429
583 1SVI GDP 13.3333
584 2CDN ADP 13.4328
585 5KDO GDP 13.5135
586 4CVN ADP 13.6126
587 1R4A GNP 13.7255
588 5KUT GDP 13.7566
589 5IFS ADP 13.9241
590 2V7Q ATP 14
591 2CK3 ANP 14
592 2V7Q ADP 14
593 2CK3 ADP 14
594 1B0U ATP 14.1221
595 4JLS 3ZE 14.4737
596 2PEZ DAT 14.5251
597 2PEZ GGZ 14.5251
598 1W7J ADP BEF 14.5695
599 1B7T ADP 14.7436
600 3KUD GDP 14.8148
601 1KK8 BEF ADP 14.9351
602 2FH5 GTP 15.1351
603 2G77 GDP 15.1515
604 2G77 AF3 15.1515
605 1US5 GLU 15.2866
606 1F2U ATP 15.4362
607 2HV8 GTP 15.625
608 2QTV GNP 16.3265
609 2VB6 ADP BEF 16.4456
610 4PFO ADP 16.4456
611 1Z0K GTP 17.3913
612 1YRB GDP 17.5573
613 3GJ3 GDP 18.1818
614 5UWR GNP 18.5185
615 2ZTS ADP 18.7251
616 1U0J ADP 19.1011
617 4XTR ADP 21.6216
618 4XTR ATP 21.6216
619 5UWT GNP 21.7391
620 3QF7 ANP 22
621 5UWH GNP 22.7273
622 5UWQ GNP 22.7273
623 3KO0 TFP 23.7624
624 2D7C GTP 23.8095
625 3ZIA ATP 25.3623
626 3ZIA ADP 25.3623
627 2W83 GTP 25.974
628 5UWP GNP 26.3158
629 1FQJ GDP 28.5714
630 1FQJ ALF 28.5714
631 6CIT GNP 28.5714
632 2HCJ GDP 29.7297
633 3ZS9 ADP ALF 42.1053
Pocket No.: 2; Query (leader) PDB : 1SVM; Ligand: ATP; Similar sites found with APoc: 15
This union binding pocket(no: 2) in the query (biounit: 1svm.bio1) has 45 residues
No: Leader PDB Ligand Sequence Similarity
1 3KIH GDL None
2 2H8H H8H 1.59151
3 1FQK ALF 2.04082
4 4GOX A3P 2.23642
5 2WPW ACO 2.65487
6 2XTN GTP 3.4188
7 4RZ3 ADP 4.0678
8 1OYF MHN 4.95868
9 4IOK ADP 5.03979
10 4UYF 73B 5.84416
11 2I4I AMP 6.36605
12 1U5R ATP 6.89655
13 5LMK 6ZK 7.07071
14 3BER AMP 8.03213
15 1WQ1 GDP 11.4458
Pocket No.: 3; Query (leader) PDB : 1SVM; Ligand: ATP; Similar sites found with APoc: 18
This union binding pocket(no: 3) in the query (biounit: 1svm.bio1) has 43 residues
No: Leader PDB Ligand Sequence Similarity
1 4XDY HIO 2.95858
2 2AL2 2PG 3.71353
3 2AL2 PEP 3.71353
4 2C3H GLC GLC 4.08163
5 5G1N PAL 4.14013
6 3KIF GDL 4.71698
7 3KC1 2T6 5.34125
8 2DUR MAN MAN 5.5336
9 5T8U LPA 5.55556
10 1CM0 COA 5.95238
11 3AQA BYH 7.03125
12 2B4B COA 8.18713
13 4KCT FDP 8.48806
14 3MWL 8OX 9.17874
15 3HQP FDP 9.28382
16 1TIQ COA 9.44444
17 5E4R 40E 10.3448
18 4JGT PYR 10.7023
Pocket No.: 4; Query (leader) PDB : 1SVM; Ligand: ATP; Similar sites found with APoc: 61
This union binding pocket(no: 4) in the query (biounit: 1svm.bio1) has 22 residues
No: Leader PDB Ligand Sequence Similarity
1 5EJ2 NAD 1.94805
2 3MJY FMN 2.02312
3 3MJY IJZ 2.02312
4 4C12 ADP 2.12202
5 1G3M A3P 2.38095
6 1G3M PCQ 2.38095
7 1XCL SAH 2.55319
8 4WOP CTP 3.11111
9 4BFW ZVW 3.14465
10 4XAQ 40F 3.18302
11 1ZED PNP 3.18302
12 1NHX PEP 3.44828
13 1NHX FTB 3.44828
14 2GMV PEP 3.44828
15 3H86 AP5 4.16667
16 1IZO PAM 4.50928
17 2Q2Y ADP 4.63215
18 2Q2Y MKR 4.63215
19 2ZE7 DST 4.74308
20 3X1Z GNP 4.79042
21 5UR1 YY9 4.82315
22 4HDQ GNP 4.96894
23 1X1R GDP 5.61798
24 1X8J A3P 5.98291
25 1GUA GNP 5.98802
26 3E5H GNP 6.17978
27 1DAK DPU 6.25
28 1DAK ADP 6.25
29 5UPK GNP 6.48649
30 4IDN GNP 6.6313
31 3QXC ATP 7.85124
32 1P7T PYR 7.95756
33 2YOH WMJ 8.57143
34 1UKZ ADP 9.35961
35 5BYK A3P 9.65251
36 5BYK OAQ 9.65251
37 6FA4 GNP 10.9827
38 6BVJ GNP 11.3772
39 6D5L GNP 11.3772
40 6D5E GNP 11.3772
41 6D56 GNP 11.3772
42 6D59 GNP 11.3772
43 6D5G GNP 11.3772
44 6BVM GNP 11.3772
45 6BVI GNP 11.3772
46 6BVL GNP 11.3772
47 6BVK GNP 11.3772
48 6D5J GNP 11.3772
49 6D5H GNP 11.3772
50 6D55 GNP 11.3772
51 6D5M GNP 11.3772
52 6D5V GNP 11.3772
53 1NVV GNP 11.4458
54 3DDC GNP 11.4458
55 1CLU DBG 11.4458
56 1Z83 AP5 11.7347
57 1QF9 ALF 11.8557
58 1QF9 ADP 11.8557
59 1QF9 C5P 11.8557
60 3QVV 3QV 13.5593
61 3QVV A3P 13.5593
Pocket No.: 5; Query (leader) PDB : 1SVM; Ligand: ATP; Similar sites found with APoc: 5
This union binding pocket(no: 5) in the query (biounit: 1svm.bio1) has 22 residues
No: Leader PDB Ligand Sequence Similarity
1 5FBK TCR 1.85676
2 1RVV INI 4.54545
3 2ZE7 AMP 4.74308
4 3C3N FMN 6.41026
5 3FSY SCA 7.53012
Pocket No.: 6; Query (leader) PDB : 1SVM; Ligand: ATP; Similar sites found with APoc: 3
This union binding pocket(no: 6) in the query (biounit: 1svm.bio1) has 46 residues
No: Leader PDB Ligand Sequence Similarity
1 4XFR CIT 5.38642
2 3GQI ACP 7.07965
3 2FKA BEF 7.75194
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