Receptor
PDB id Resolution Class Description Source Keywords
1SZC 1.75 Å EC: 3.5.1.- STRUCTURAL BASIS FOR NICOTINAMIDE CLEAVAGE AND ADP-RIBOSE TR NAD+-DEPENDENT SIR2 HISTONE/PROTEIN DEACETYLASES SACCHAROMYCES CEREVISIAE SIR2 SIRTUIN HISTONE DEACETYLASE GENE REGULATION
Ref.: STRUCTURAL BASIS FOR NICOTINAMIDE CLEAVAGE AND ADP-TRANSFER BY NAD(+)-DEPENDENT SIR2 HISTONE/PROTEIN DEACETYLASES. PROC.NATL.ACAD.SCI.USA V. 101 8563 2004
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
CL A:702;
Invalid;
none;
submit data
35.453 Cl [Cl-]
CNA A:1001;
Valid;
none;
submit data
662.46 C22 H30 N7 O13 P2 c1cc(...
GOL A:1989;
A:1990;
A:1991;
A:1992;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
submit data
92.094 C3 H8 O3 C(C(C...
LYS GLY GLY ALA ALY ARG HIS ARG LYS ILE B:12;
Valid;
none;
submit data
939.138 n/a O=C(N...
ZN A:701;
Part of Protein;
none;
submit data
65.409 Zn [Zn+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1SZD 1.5 Å EC: 3.5.1.- STRUCTURAL BASIS FOR NICOTINAMIDE CLEAVAGE AND ADP-RIBOSE TR NAD+-DEPENDENT SIR2 HISTONE/PROTEIN DEACETYLASES SACCHAROMYCES CEREVISIAE HST2 SIR2 SIRTUIN HISTONE DEACETYLASE PROTEIN DEACETYLASREGULATION
Ref.: STRUCTURAL BASIS FOR NICOTINAMIDE CLEAVAGE AND ADP-TRANSFER BY NAD(+)-DEPENDENT SIR2 HISTONE/PROTEIN DEACETYLASES. PROC.NATL.ACAD.SCI.USA V. 101 8563 2004
Members (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 27 families.
1 1SZD Kd = 29.16 uM APR C15 H23 N5 O14 P2 c1nc(c2c(n....
2 1Q1A - OAD C17 H25 N5 O15 P2 CC(=O)O[C@....
3 1SZC - CNA C22 H30 N7 O13 P2 c1cc(c[n+]....
70% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 25 families.
1 1SZD Kd = 29.16 uM APR C15 H23 N5 O14 P2 c1nc(c2c(n....
2 1Q1A - OAD C17 H25 N5 O15 P2 CC(=O)O[C@....
3 1SZC - CNA C22 H30 N7 O13 P2 c1cc(c[n+]....
50% Homology Family (35)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 18 families.
1 1SZD Kd = 29.16 uM APR C15 H23 N5 O14 P2 c1nc(c2c(n....
2 1Q1A - OAD C17 H25 N5 O15 P2 CC(=O)O[C@....
3 1SZC - CNA C22 H30 N7 O13 P2 c1cc(c[n+]....
4 4RMG ic50 = 0.14 uM 3TE C22 H20 N4 O S2 Cc1cc(nc(n....
5 4R8M - PRO LYS LYS THR GLY 3LX n/a n/a
6 4RMH - 3TE C22 H20 N4 O S2 Cc1cc(nc(n....
7 5DY4 ic50 = 0.21 uM 5GN C22 H19 Br N4 O S2 Cc1cc(nc(n....
8 4Y6L - THR ALA ARG MYK SER THR GLY n/a n/a
9 5MAR ic50 = 41.2 uM 7KE C11 H11 Cl N2 O2 c1cc(ccc1c....
10 3ZGV - AR6 C15 H23 N5 O14 P2 c1nc(c2c(n....
11 4Y6O - LEU PRO LYS MYK THR GLY GLY n/a n/a
12 4RMJ - NCA C6 H6 N2 O c1cc(cnc1)....
13 5DY5 ic50 = 0.118 uM 5GR C28 H27 N7 O2 S2 Cc1cc(nc(n....
14 5D7P ic50 = 20 uM OCZ C13 H13 Cl N2 O c1cc2c(cc1....
15 4RMI - 3TK C18 H18 N4 O S2 Cc1cc(nc(n....
16 5MAT ic50 = 0.58 uM 7KJ C28 H28 N4 O3 S Cc1c(c(on1....
17 4Y6Q - OMR C29 H49 N5 O15 P2 CCCCCCCCCC....
18 5D7Q ic50 = 2.8 uM 4I5 C14 H15 Cl N2 O c1cc2c(cc1....
19 5G4C Kd = 13.7 uM ARG ALA ALA 6G4 THR n/a n/a
20 5D7O - AR6 C15 H23 N5 O14 P2 c1nc(c2c(n....
21 4FZ3 - ACE ARG HIS LYS ALY MCM n/a n/a
22 4JT9 ic50 = 0.0072 uM 1NS C15 H21 N5 O3 S2 CS(=O)(=O)....
23 5BWO - PLM GLN THR ALA ARG LYS SER THR GLY GLY TRP n/a n/a
24 4JT8 ic50 = 0.033 uM 1NR C19 H27 N5 O2 S CC(C)(C)C(....
25 4BV3 Kd = 16.5 uM OCZ C13 H13 Cl N2 O c1cc2c(cc1....
26 4BVH - OAD C17 H25 N5 O15 P2 CC(=O)O[C@....
27 4C7B - ARG HIS LYS FDL n/a n/a
28 4C78 - BVB C14 H11 Br O2 c1cc(ccc1/....
29 5BWN - GLN THR ALA ARG MYK SER THR GLY GLY TRP n/a n/a
30 4BN4 - AR6 C15 H23 N5 O14 P2 c1nc(c2c(n....
31 4JSR ic50 = 0.004 uM 1NQ C22 H26 N6 O3 S2 CCNC(=O)c1....
32 4BVE - THR ARG SER GLY FZN VAL MET ARG ARG LEU n/a n/a
33 4BVB - AR6 C15 H23 N5 O14 P2 c1nc(c2c(n....
34 4FVT - CNA C22 H30 N7 O13 P2 c1cc(c[n+]....
35 4I5I - 4I5 C14 H15 Cl N2 O c1cc2c(cc1....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: CNA; Similar ligands found: 239
No: Ligand ECFP6 Tc MDL keys Tc
1 CNA 1 1
2 NXX 0.644068 0.972973
3 DND 0.644068 0.972973
4 NAD 0.642276 0.972603
5 A2D 0.62 0.958904
6 NAD IBO 0.608 0.909091
7 BA3 0.607843 0.958904
8 A3D 0.606299 0.959459
9 AP5 0.601942 0.958904
10 B4P 0.601942 0.958904
11 M33 0.590476 0.92
12 ATP 0.584906 0.932432
13 AQP 0.579439 0.932432
14 APR 0.579439 0.932432
15 AR6 0.579439 0.932432
16 5FA 0.579439 0.932432
17 3OD 0.577586 0.933333
18 SAP 0.574074 0.884615
19 AGS 0.574074 0.884615
20 OAD 0.573913 0.933333
21 ADP 0.571429 0.932432
22 ACP 0.570093 0.907895
23 AN2 0.566038 0.92
24 OOB 0.561404 0.945946
25 CA0 0.560748 0.933333
26 NAJ PYZ 0.559702 0.8875
27 AD9 0.559633 0.907895
28 A1R 0.556522 0.897436
29 ACQ 0.54955 0.907895
30 5AL 0.544643 0.92
31 ABM 0.542857 0.881579
32 GTA 0.540323 0.9
33 NAX 0.539683 0.911392
34 A22 0.53913 0.945946
35 00A 0.538462 0.897436
36 DLL 0.538462 0.945946
37 1ZZ 0.537815 0.831325
38 PRX 0.536364 0.858974
39 ANP 0.535714 0.907895
40 ADX 0.53211 0.841463
41 WAQ 0.529412 0.873418
42 AMP 0.528846 0.905405
43 A 0.528846 0.905405
44 TXD 0.527559 0.922078
45 6V0 0.527559 0.910256
46 NAI 0.527559 0.922078
47 50T 0.527273 0.894737
48 ATF 0.526316 0.896104
49 OMR 0.523438 0.843373
50 TXE 0.523438 0.922078
51 NAP 0.521739 0.959459
52 SRP 0.521739 0.921053
53 8QN 0.521368 0.92
54 3UK 0.521008 0.933333
55 NHD 0.518797 0.945946
56 4AD 0.516949 0.96
57 ADQ 0.516949 0.933333
58 PAJ 0.516949 0.875
59 9SN 0.516393 0.886076
60 NAQ 0.514493 0.910256
61 AHX 0.512605 0.910256
62 NFD 0.511111 0.922078
63 ZID 0.510791 0.959459
64 AMP NAD 0.510791 0.921053
65 NAD BBN 0.510067 0.878049
66 SON 0.509091 0.896104
67 APC 0.508929 0.896104
68 5SV 0.508475 0.817073
69 25L 0.508197 0.945946
70 48N 0.507812 0.886076
71 NAE 0.507246 0.934211
72 AMP MG 0.504673 0.881579
73 A12 0.504587 0.896104
74 AP2 0.504587 0.896104
75 AMO 0.504202 0.946667
76 PR8 0.504132 0.864198
77 DZD 0.503704 0.898734
78 NAD CJ3 0.503311 0.847059
79 FA5 0.5 0.946667
80 FYA 0.5 0.92
81 BIS 0.5 0.873418
82 TXA 0.5 0.921053
83 ME8 0.5 0.853659
84 PTJ 0.5 0.8625
85 T5A 0.496241 0.878049
86 8ID 0.496183 0.923077
87 AP0 0.496183 0.886076
88 TAT 0.495652 0.896104
89 GAP 0.495652 0.907895
90 SRA 0.495327 0.858974
91 NA0 0.492958 0.946667
92 A4P 0.492424 0.857143
93 UP5 0.492308 0.934211
94 4UV 0.492063 0.909091
95 LAD 0.491803 0.875
96 ADP MG 0.491071 0.894737
97 AU1 0.491071 0.907895
98 LAQ 0.488372 0.831325
99 G3A 0.488189 0.910256
100 YAP 0.488 0.934211
101 NB8 0.487805 0.910256
102 ADP BEF 0.486726 0.871795
103 BEF ADP 0.486726 0.871795
104 N01 0.485507 0.945946
105 COD 0.485294 0.825581
106 AFH 0.484375 0.875
107 4UU 0.484375 0.909091
108 G5P 0.484375 0.910256
109 XAH 0.484127 0.853659
110 25A 0.483333 0.932432
111 NDC 0.482993 0.910256
112 EAD 0.482517 0.911392
113 4UW 0.480916 0.875
114 NDE 0.479452 0.946667
115 ADP PO3 0.478261 0.931507
116 RBY 0.478261 0.896104
117 ADV 0.478261 0.896104
118 NJP 0.477941 0.96
119 IOT 0.477612 0.823529
120 DAL AMP 0.475 0.92
121 NAD NDT 0.475 0.739583
122 ATP MG 0.474138 0.894737
123 ADJ 0.474074 0.865854
124 139 0.474074 0.911392
125 4TC 0.473684 0.910256
126 MYR AMP 0.472 0.831325
127 P1H 0.469388 0.888889
128 NGD 0.466667 0.923077
129 NAD TDB 0.466258 0.705882
130 TYM 0.466165 0.946667
131 MAP 0.46281 0.884615
132 ADP ALF 0.462185 0.860759
133 ALF ADP 0.462185 0.860759
134 YLP 0.462121 0.833333
135 BT5 0.460432 0.823529
136 NAJ 0.459854 0.945946
137 ANP MG 0.458333 0.884615
138 ADP VO4 0.458333 0.92
139 VO4 ADP 0.458333 0.92
140 M24 0.457746 0.864198
141 TAP 0.455172 0.897436
142 YLC 0.451852 0.853659
143 YLB 0.451852 0.833333
144 7MD 0.450382 0.876543
145 ADP BMA 0.448 0.933333
146 AMP DBH 0.446154 0.907895
147 FB0 0.443709 0.797753
148 NAJ PZO 0.443662 0.886076
149 AHZ 0.443609 0.831325
150 0WD 0.442857 0.910256
151 54H 0.442623 0.781609
152 A2R 0.442623 0.92
153 VMS 0.442623 0.781609
154 7MC 0.441176 0.855422
155 PAP 0.440678 0.918919
156 7D4 0.439655 0.846154
157 ITT 0.439655 0.88
158 TSB 0.439024 0.811765
159 AYB 0.438849 0.823529
160 TYR AMP 0.438462 0.946667
161 A5A 0.438017 0.8
162 YLY 0.4375 0.823529
163 AOC 0.4375 0.789474
164 G5A 0.436975 0.793103
165 TAD 0.43609 0.875
166 AVV 0.435484 0.8625
167 5AS 0.434783 0.752809
168 3AT 0.433333 0.906667
169 A A 0.433071 0.932432
170 BTX 0.432624 0.833333
171 2A5 0.432203 0.858974
172 DSZ 0.432 0.813953
173 LSS 0.432 0.775281
174 NPW 0.431655 0.9
175 YLA 0.431655 0.833333
176 52H 0.430894 0.772727
177 ATP A A A 0.430769 0.945205
178 UPA 0.430657 0.922078
179 6AD 0.429752 0.851852
180 LPA AMP 0.42963 0.831325
181 N0B 0.428571 0.855422
182 ATR 0.428571 0.905405
183 53H 0.427419 0.772727
184 6FA 0.425806 0.855422
185 ODP 0.425532 0.923077
186 NA7 0.425197 0.896104
187 LEU LMS 0.425197 0.795455
188 ALF ADP 3PG 0.423358 0.851852
189 LA8 ALF 3PG 0.423358 0.851852
190 SSA 0.422764 0.813953
191 ARG AMP 0.422222 0.843373
192 MTA 0.422018 0.74359
193 P5A 0.421875 0.758242
194 NDO 0.421769 0.933333
195 NDP 0.421429 0.910256
196 NSS 0.420635 0.835294
197 FAD 0.420382 0.865854
198 FAS 0.420382 0.865854
199 5N5 0.419048 0.786667
200 JB6 0.418605 0.873418
201 TXP 0.41844 0.910256
202 NZQ 0.41844 0.898734
203 7D3 0.417391 0.846154
204 NVA LMS 0.417323 0.795455
205 EP4 0.416667 0.725
206 5CA 0.416 0.813953
207 5CD 0.415094 0.773333
208 3DH 0.414414 0.74359
209 A3P 0.413793 0.905405
210 XYA 0.413462 0.810811
211 ADN 0.413462 0.810811
212 RAB 0.413462 0.810811
213 AF3 ADP 3PG 0.413043 0.851852
214 DTA 0.412844 0.779221
215 4TA 0.412587 0.865854
216 SFD 0.411392 0.747368
217 3AM 0.410714 0.866667
218 F2N 0.410714 0.827586
219 FDA 0.410256 0.825581
220 FNK 0.409938 0.818182
221 62F 0.409938 0.853659
222 DTP 0.409836 0.87013
223 AR6 AR6 0.407407 0.932432
224 P5F 0.407186 0.837209
225 PPS 0.406504 0.819277
226 ARU 0.40625 0.807229
227 YSA 0.406015 0.813953
228 AV2 0.403226 0.857143
229 649 0.402878 0.777778
230 XNP 0.402778 0.8875
231 A4D 0.401869 0.786667
232 DCA 0.401361 0.816092
233 ETB 0.401361 0.825581
234 5X8 0.4 0.779221
235 GSU 0.4 0.793103
236 KAA 0.4 0.766667
237 M2T 0.4 0.728395
238 FA9 0.4 0.878049
239 SMM 0.4 0.72093
Ligand no: 2; Ligand: LYS GLY GLY ALA ALY ARG HIS ARG LYS ILE; Similar ligands found: 39
No: Ligand ECFP6 Tc MDL keys Tc
1 LYS GLY GLY ALA ALY ARG HIS ARG LYS ILE 1 1
2 LYS GLY GLY ALA ALY ARG HIS ARG 0.826087 0.965517
3 LYS GLY GLY ALA ALY ARG HIS ARG LYS VAL 0.624 0.932203
4 ARG HIS LYS ALY LEU MET PHE LYS 0.541667 0.84127
5 ALA LYS ARG HIS ARG MLZ VAL LEU ARG ASP 0.521739 0.9
6 ARG HIS LYS FDL 0.503497 0.716216
7 ILE LEU ALA LYS PHE LEU HIS ARG LEU 0.503401 0.836066
8 THR SER ARG HIS LYS ALY LEU MET ALA 0.496599 0.782609
9 ACE ARG HIS ALY ALY MCM 0.496454 0.716216
10 ALA LYS ARG HIS ARG LYS VAL LEU ARG ASP 0.485714 0.868852
11 LYS ARG LYS ARG LYS ARG LYS ARG 0.482143 0.732143
12 HIS HIS ALA SER PRO ARG LYS 0.476821 0.75
13 SER THR GLY GLY VAL M3L LYS PRO HIS ARG 0.473988 0.746667
14 GLY ALA ARG ALA HIS SER SER 0.469697 0.84127
15 LYS ILE LEU HIS ARG LEU LEU GLN ASP SER 0.461538 0.8
16 ILE LEU GLY LYS PHE LEU HIS ARG LEU 0.456954 0.84127
17 ALA HIS ALA LYS ALA 0.455285 0.785714
18 ALA LYS PHE ARG HIS ASP 0.452555 0.836066
19 HIS LYS ILE LEU HIS ARG LEU LEU GLN GLU 0.451613 0.83871
20 ARG ARG LYS TRP ARG ARG TRP HIS LEU 0.451389 0.8125
21 GLU ALY ARG 0.449153 0.758621
22 LYS ARG ARG ARG HIS PRO SER 0.448276 0.772727
23 ASP ALA GLU PHE ARG HIS ASP SER 0.448276 0.819672
24 LYS GLY HIS HIS HIS HIS HIS HIS 0.44697 0.775862
25 HIS LYS ILE LEU HIS ARG LEU LEU GLN ASP 0.445161 0.825397
26 ARG GLY PHE ALA LEU M3L SER THR HIS GLY 0.439759 0.756757
27 LYS ARG ARG ARG HIS PRO SER GLY 0.439189 0.764706
28 ACE ARG HIS LYS ALY MCM 0.436709 0.706667
29 ARG ARG ARG TRP HIS ARG TRP ARG LEU 0.423611 0.796875
30 GLY HIS LYS ILE LEU HIS ARG LEU LEU GLN 0.416107 0.854839
31 ARG ARG ARG ARG ARG ARG ARG ARG 0.415929 0.714286
32 THR ASP HIS GLY ALA GLU 0.411765 0.746032
33 LYS ILE LEU HIS ARG LEU LEU GLN ASP 0.410959 0.836066
34 PCA PHE ARG HIS ASP SER 0.409396 0.806452
35 THR ALA ARG M3L SER THR GLY GLY LYS ALA 0.406667 0.638889
36 ARG ARG LEU LEU ARG GLY HIS ASN GLN TYR 0.40625 0.779412
37 LYS HIS LYS 0.403361 0.724138
38 GLU VAL ALA PRO PRO GLU TYR HIS ARG LYS 0.403315 0.774648
39 ARG ARG LYS TRP CIR ARG TRP HIS LEU 0.401198 0.8
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1SZD; Ligand: APR; Similar sites found: 39
This union binding pocket(no: 1) in the query (biounit: 1szd.bio1) has 36 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 4Q3F TLA 0.04473 0.41067 None
2 5JE8 NAD 0.004331 0.41836 2.3569
3 1HDG NAD 0.006351 0.40575 2.3569
4 2FK8 SAM 0.009655 0.40913 2.6936
5 1T9D 1MM 0.001811 0.43768 3.0303
6 1T9D PYD 0.001752 0.43768 3.0303
7 1T9D P25 0.002058 0.4349 3.0303
8 1T9D FAD 0.0004752 0.4314 3.0303
9 2C31 ADP 0.002616 0.426 3.0303
10 2C31 TZD 0.002713 0.426 3.0303
11 2Q28 ADP 0.00004599 0.40652 3.0303
12 2V3V MGD 0.01081 0.40231 3.0303
13 5A3B APR 0.000000008005 0.55061 3.367
14 4M73 M72 0.001086 0.41495 3.367
15 4M73 SAH 0.00102 0.41473 3.367
16 1V6A TRE 0.01643 0.43192 3.7037
17 2NXE SAM 0.008373 0.41817 3.93701
18 2IXB NAD 0.003068 0.40561 4.3771
19 3LST SAH 0.015 0.41635 4.88506
20 3B9Q MLI 0.004282 0.46223 5.05051
21 3I9U DTU 0.02938 0.40672 5.32319
22 4KGD FAD 0.000519 0.4529 5.38721
23 4KGD TDP 0.00102 0.44074 5.38721
24 1YBH FAD 0.0005466 0.42805 5.38721
25 2VDV SAM 0.02199 0.40813 6.09756
26 1XDS SAM 0.01081 0.42337 6.39731
27 1G55 SAH 0.01608 0.40209 6.39731
28 3EYA FAD 0.0007775 0.4177 7.40741
29 4YDD MGD 0.00329 0.4227 9.42761
30 4YDD MD1 0.00329 0.4227 9.42761
31 1O97 AMP 0.0009155 0.43433 10.6061
32 1O97 FAD 0.0009155 0.43433 10.6061
33 1LOB MMA 0.04493 0.40268 11.5385
34 1V5F FAD 0.0006311 0.446 13.1313
35 1EFV FAD 0.003794 0.41157 13.8047
36 1EFV AMP 0.004741 0.40787 13.8047
37 5N53 8NB 0.04138 0.41042 16.4103
38 3U31 NAD 0.000000001713 0.54255 29.6552
39 1M2K APR 0.0000000008811 0.58612 38.1526
Pocket No.: 2; Query (leader) PDB : 1SZD; Ligand: APR; Similar sites found: 52
This union binding pocket(no: 2) in the query (biounit: 1szd.bio2) has 36 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 2E1A MSE 0.01379 0.4116 None
2 1RP0 AHZ 0.0002566 0.42944 1.05634
3 2NCD ADP 0.001048 0.47237 1.3468
4 1VBI NAD 0.00003936 0.43852 1.3468
5 2DT5 NAD 0.00009629 0.40157 1.89573
6 4COQ SAN 0.005277 0.44596 2.02429
7 1Z44 NPO 0.01248 0.46361 2.3569
8 1PEA ACM 0.02469 0.42491 2.3569
9 4B63 ORN 0.01003 0.40426 2.6936
10 4B63 FAD 0.01003 0.40426 2.6936
11 1SB8 UD2 0.001099 0.40004 2.6936
12 2Q37 3AL 0.01744 0.41617 2.76243
13 1UXG NAD 0.0002955 0.40237 2.91262
14 1UXG FUM 0.0002955 0.40237 2.91262
15 1KGQ NPI 0.002608 0.40237 2.91971
16 1KGQ SCO 0.002906 0.40184 2.91971
17 4Q0A 4OA 0.001118 0.42979 3.0303
18 4ASJ N6A 0.001264 0.41301 3.07167
19 1V7R CIT 0.04609 0.42305 3.22581
20 1SS4 GSH 0.003936 0.49721 3.26797
21 1SS4 CIT 0.003777 0.47098 3.26797
22 3MAG 3MA 0.001882 0.50035 3.7037
23 2QLX RM4 0.01285 0.43325 3.7037
24 3MAG SAH 0.001097 0.42608 3.7037
25 3F81 STT 0.001276 0.49969 3.82514
26 1G8S MET 0.006065 0.44308 3.91304
27 4KQL 1SG 0.0009167 0.40873 4.0404
28 2XVE FAD 0.0009289 0.40856 4.0404
29 3SHR CMP 0.001327 0.45009 4.3771
30 1W7J ADP BEF 0.006845 0.4044 4.3771
31 2XCG XCG 0.00009735 0.40066 4.7138
32 4IXW IXW 0.02091 0.40374 4.72441
33 2RHQ GAX 0.002562 0.40603 4.7619
34 4PLG NAI 0.0002653 0.40236 5.38721
35 4PLG OXM 0.0002653 0.40236 5.38721
36 1N9L FMN 0.002142 0.41944 5.50459
37 1M5B BN1 0.0006134 0.41063 5.70342
38 1SJW NGV 0.00993 0.40178 6.25
39 4DEM YS4 0.0007932 0.42133 6.73401
40 1E8G FCR 0.003141 0.40731 6.73401
41 1E8G FAD 0.005285 0.40124 6.73401
42 2F2U M77 0.01958 0.40098 6.73401
43 3S9K CIT 0.00377 0.50651 6.77966
44 2YVF FAD 0.001032 0.40648 7.07071
45 2YVF NAD 0.001096 0.40648 7.07071
46 1RYI GOA 0.0003828 0.40508 8.75421
47 1RYI FAD 0.0003935 0.40476 8.75421
48 3FC4 EDO 0.0008796 0.40363 8.75421
49 1H82 FAD 0.001344 0.40084 8.75421
50 1H82 GZZ 0.001614 0.40084 8.75421
51 1WDA BAG 0.001539 0.45277 11.1111
52 1V5F TPP 0.000064 0.48003 13.1313
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