Receptor
PDB id Resolution Class Description Source Keywords
1T7D 2.47 Å EC: 3.4.21.89 CRYSTAL STRUCTURE OF ESCHERICHIA COLI TYPE I SIGNAL PEPTIDAS COMPLEX WITH A LIPOPEPTIDE INHIBITOR ESCHERICHIA COLI SIGNAL PEPTIDASE SER/LYS DYAD HYDROLASE LIPOPEPTIDE ANTIBIARYL BRIDGE HYDROLASE-ANTIBIOTIC COMPLEX
Ref.: CRYSTALLOGRAPHIC AND BIOPHYSICAL ANALYSIS OF A BACT SIGNAL PEPTIDASE IN COMPLEX WITH A LIPOPEPTIDE BASE INHIBITOR. J.BIOL.CHEM. V. 279 30781 2004
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
DSE DAL GLY 5PG ALA TYR C:1;
D:1;
 Valid;
Valid;
 none;
none;
 Kd = 0.000000064 M
642.666 n/a O=C(N...
M12 C:0;
D:0;
 Invalid;
Invalid;
 none;
none;
 submit data
200.318 C12 H24 O2 CC(C)...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1T7D 2.47 Å EC: 3.4.21.89 CRYSTAL STRUCTURE OF ESCHERICHIA COLI TYPE I SIGNAL PEPTIDAS COMPLEX WITH A LIPOPEPTIDE INHIBITOR ESCHERICHIA COLI SIGNAL PEPTIDASE SER/LYS DYAD HYDROLASE LIPOPEPTIDE ANTIBIARYL BRIDGE HYDROLASE-ANTIBIOTIC COMPLEX
Ref.: CRYSTALLOGRAPHIC AND BIOPHYSICAL ANALYSIS OF A BACT SIGNAL PEPTIDASE IN COMPLEX WITH A LIPOPEPTIDE BASE INHIBITOR. J.BIOL.CHEM. V. 279 30781 2004
Members (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 1T7D Kd = 0.000000064 M DSE DAL GLY 5PG ALA TYR n/a n/a
2 3S04 - DSE DAL GLY 02V ALA TYR 02U RAM n/a n/a
3 3IIQ ic50 = 610 uM JZA C7 H12 N2 O4 S C1COCCN1C(....
70% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 1T7D Kd = 0.000000064 M DSE DAL GLY 5PG ALA TYR n/a n/a
2 3S04 - DSE DAL GLY 02V ALA TYR 02U RAM n/a n/a
3 3IIQ ic50 = 610 uM JZA C7 H12 N2 O4 S C1COCCN1C(....
50% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 1T7D Kd = 0.000000064 M DSE DAL GLY 5PG ALA TYR n/a n/a
2 3S04 - DSE DAL GLY 02V ALA TYR 02U RAM n/a n/a
3 3IIQ ic50 = 610 uM JZA C7 H12 N2 O4 S C1COCCN1C(....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: DSE DAL GLY 5PG ALA TYR; Similar ligands found: 2
No: Ligand ECFP6 Tc MDL keys Tc
1 DSE DAL GLY 5PG ALA TYR 1 1
2 DSE DAL GLY 02V ALA TYR 02U RAM 0.578571 0.910448
Similar Ligands (3D)
Ligand no: 1; Ligand: DSE DAL GLY 5PG ALA TYR; Similar ligands found: 0
No: Ligand Similarity coefficient
Similar Binding Sites (Proteins are less than 50% similar to leader) APoc FAQ
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