Receptor
PDB id Resolution Class Description Source Keywords
1TLL 2.3 Å EC: 1.14.13.39 CRYSTAL STRUCTURE OF RAT NEURONAL NITRIC-OXIDE SYNTHASE REDUCTASE MODULE AT 2.3 A RESOLUTION. RATTUS NORVEGICUS NITRIC-OXIDE SYNTHASE REDUCTASE MODULE FMN FAD NADP+ OXIDOREDUCTASE
Ref.: STRUCTURAL BASIS FOR ISOZYME-SPECIFIC REGULATION OF ELECTRON TRANSFER IN NITRIC-OXIDE SYNTHASE J.BIOL.CHEM. V. 279 37918 2004
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
FAD A:1452;
B:2452;
Valid;
Valid;
none;
none;
submit data
785.55 C27 H33 N9 O15 P2 Cc1cc...
FMN A:1451;
B:2451;
Valid;
Valid;
none;
none;
submit data
456.344 C17 H21 N4 O9 P Cc1cc...
NAP A:1453;
B:2453;
Valid;
Valid;
none;
none;
submit data
743.405 C21 H28 N7 O17 P3 c1cc(...
SO3 A:1500;
B:2500;
Invalid;
Invalid;
none;
none;
submit data
80.063 O3 S [O-]S...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1TLL 2.3 Å EC: 1.14.13.39 CRYSTAL STRUCTURE OF RAT NEURONAL NITRIC-OXIDE SYNTHASE REDUCTASE MODULE AT 2.3 A RESOLUTION. RATTUS NORVEGICUS NITRIC-OXIDE SYNTHASE REDUCTASE MODULE FMN FAD NADP+ OXIDOREDUCTASE
Ref.: STRUCTURAL BASIS FOR ISOZYME-SPECIFIC REGULATION OF ELECTRON TRANSFER IN NITRIC-OXIDE SYNTHASE J.BIOL.CHEM. V. 279 37918 2004
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 10 families.
1 1TLL - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 7 families.
1 1TLL - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
50% Homology Family (5)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 1DDG - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
2 4DQL - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
3 4DQK - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
4 1F20 - NAP C21 H28 N7 O17 P3 c1cc(c[n+]....
5 1TLL - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: FAD; Similar ligands found: 119
No: Ligand ECFP6 Tc MDL keys Tc
1 FAS 1 1
2 FAD 1 1
3 FAY 0.859259 0.9875
4 RFL 0.852941 0.963855
5 6FA 0.794118 0.987654
6 DAL FAD PER 0.772414 0.951807
7 FAE 0.751773 0.987654
8 SFD 0.651007 0.860215
9 FDA 0.641892 0.906977
10 FNK 0.602564 0.876405
11 62F 0.572327 0.939024
12 F2N 0.566265 0.886364
13 FMN 0.543307 0.876543
14 FA9 0.526316 0.939759
15 6YU 0.516304 0.860215
16 CNV FAD 0.511905 0.908046
17 P6G FDA 0.511628 0.908046
18 FAD NBT 0.508876 0.83871
19 A2D 0.504065 0.875
20 P5F 0.491329 0.941176
21 FAD CNX 0.488506 0.8125
22 APR 0.488372 0.851852
23 AR6 0.488372 0.851852
24 AGS 0.484615 0.811765
25 SAP 0.484615 0.811765
26 M33 0.484375 0.864198
27 BA3 0.484127 0.875
28 FAD NBA 0.480663 0.802083
29 ATP 0.48062 0.851852
30 B4P 0.480315 0.875
31 ADP 0.480315 0.851852
32 AP5 0.480315 0.875
33 ANP 0.477273 0.831325
34 AQP 0.476923 0.851852
35 5FA 0.476923 0.851852
36 48N 0.469388 0.902439
37 OAD 0.467626 0.876543
38 GTA 0.465753 0.892857
39 AN2 0.465116 0.841463
40 AD9 0.462121 0.831325
41 3OD 0.460993 0.876543
42 RBF 0.460938 0.790123
43 FB0 0.460606 0.835165
44 139 0.460526 0.858824
45 AP0 0.46 0.835294
46 A22 0.459854 0.864198
47 ACP 0.458015 0.853659
48 8QN 0.456522 0.864198
49 PRX 0.454545 0.831325
50 A1R 0.453237 0.86747
51 G3A 0.452055 0.902439
52 T5A 0.45098 0.872093
53 G5P 0.44898 0.902439
54 ATF 0.448529 0.821429
55 50T 0.44697 0.819277
56 ACQ 0.444444 0.853659
57 PAJ 0.442857 0.847059
58 ADQ 0.442857 0.853659
59 5AL 0.441176 0.864198
60 ADX 0.439394 0.775281
61 CA0 0.439394 0.853659
62 A4P 0.437909 0.831461
63 25L 0.4375 0.864198
64 P33 FDA 0.436464 0.817204
65 5SV 0.435714 0.793103
66 TXE 0.434211 0.890244
67 OMR 0.434211 0.818182
68 ABM 0.434109 0.829268
69 A 0.433071 0.82716
70 AMP 0.433071 0.82716
71 4AD 0.432624 0.855422
72 ADJ 0.432258 0.818182
73 BIS 0.430556 0.802326
74 SRA 0.429688 0.788235
75 AFH 0.42953 0.825581
76 TXD 0.427632 0.890244
77 NXX 0.427632 0.865854
78 UP5 0.427632 0.878049
79 DND 0.427632 0.865854
80 6V0 0.427632 0.857143
81 SRP 0.42446 0.843373
82 PR8 0.423611 0.837209
83 TAT 0.423358 0.821429
84 AMO 0.422535 0.865854
85 PTJ 0.42069 0.835294
86 FYA 0.42069 0.864198
87 TXA 0.42069 0.865854
88 CNA 0.420382 0.865854
89 00A 0.41958 0.823529
90 AHX 0.41958 0.835294
91 MAP 0.41844 0.811765
92 NAI 0.418301 0.845238
93 AU1 0.41791 0.831325
94 AP2 0.416667 0.843373
95 A12 0.416667 0.843373
96 25A 0.415493 0.851852
97 AMP MG 0.415385 0.785714
98 COD 0.415094 0.842697
99 ADP BEF 0.414815 0.77907
100 BEF ADP 0.414815 0.77907
101 4TC 0.412903 0.879518
102 APC 0.411765 0.843373
103 NB8 0.410959 0.835294
104 ME8 0.410959 0.806818
105 1ZZ 0.410959 0.806818
106 4UW 0.409091 0.825581
107 NAX 0.409091 0.837209
108 RBY 0.408759 0.843373
109 ADV 0.408759 0.843373
110 ADP MG 0.407407 0.797619
111 P1H 0.405882 0.818182
112 OOB 0.405594 0.864198
113 A A 0.40411 0.829268
114 LAD 0.40411 0.825581
115 UPA 0.403846 0.86747
116 4UU 0.401316 0.833333
117 A3D 0.401235 0.876543
118 DLL 0.4 0.864198
119 XAH 0.4 0.806818
Ligand no: 2; Ligand: FMN; Similar ligands found: 16
No: Ligand ECFP6 Tc MDL keys Tc
1 FMN 1 1
2 RBF 0.75641 0.876712
3 RS3 0.571429 0.831169
4 FAS 0.543307 0.876543
5 FAD 0.543307 0.876543
6 FAE 0.539062 0.865854
7 DAL FAD PER 0.5 0.833333
8 LFN 0.475 0.643836
9 C3F 0.473684 0.74359
10 CF4 0.463918 0.734177
11 FAY 0.446043 0.864198
12 FNR 0.444444 0.909091
13 RFL 0.442857 0.845238
14 4LS 0.411215 0.875
15 1VY 0.406593 0.769231
16 DLZ 0.404494 0.782051
Ligand no: 3; Ligand: NAP; Similar ligands found: 127
No: Ligand ECFP6 Tc MDL keys Tc
1 NAP 1 1
2 NA0 0.881356 0.986301
3 TAP 0.872881 0.934211
4 NDO 0.840336 0.972603
5 NAD 0.811966 0.986111
6 N01 0.733871 0.958904
7 A3D 0.712 0.972603
8 NBP 0.707692 0.935065
9 NAD IBO 0.688 0.921053
10 NHD 0.68254 0.958904
11 NJP 0.661417 0.972973
12 NAJ PYZ 0.659091 0.898734
13 NFD 0.658915 0.934211
14 DND 0.619048 0.959459
15 NXX 0.619048 0.959459
16 ZID 0.605839 0.972603
17 NAQ 0.59854 0.922078
18 ATR 0.59292 0.917808
19 NAE 0.591241 0.946667
20 NDE 0.58042 0.986301
21 A22 0.571429 0.958904
22 AMP NAD 0.571429 0.933333
23 NAJ 0.567164 0.986111
24 A2R 0.563025 0.932432
25 NDC 0.561644 0.922078
26 NA7 0.552846 0.907895
27 ODP 0.551471 0.935065
28 A2P 0.539823 0.930556
29 8ID 0.537313 0.910256
30 NAD BBN 0.525974 0.865854
31 NPW 0.525547 0.8875
32 CNA 0.521739 0.959459
33 NZQ 0.521739 0.910256
34 NAD CJ3 0.519231 0.835294
35 NDP 0.514493 0.922078
36 PO4 PO4 A A A A PO4 0.503937 0.930556
37 DG1 0.503401 0.922078
38 1DG 0.503401 0.922078
39 NAD TDB 0.5 0.696078
40 TXP 0.5 0.922078
41 NMN AMP PO4 0.492958 0.921053
42 XNP 0.492958 0.875
43 25L 0.492308 0.958904
44 25A 0.492063 0.972222
45 NAD NDT 0.490909 0.747368
46 NMN 0.486726 0.888889
47 NGD 0.485714 0.935065
48 2AM 0.477876 0.891892
49 ADP 0.458333 0.945205
50 PAP 0.451613 0.931507
51 ADP MG 0.45082 0.906667
52 BEF ADP 0.447154 0.883117
53 ADP BEF 0.447154 0.883117
54 A2D 0.445378 0.945205
55 AN2 0.442623 0.932432
56 ADP PO3 0.44 0.944444
57 SAP 0.44 0.896104
58 AGS 0.44 0.896104
59 M33 0.439024 0.906667
60 AR6 AR6 0.438849 0.945205
61 BA3 0.438017 0.945205
62 ATP MG 0.436508 0.906667
63 ADP BMA 0.43609 0.92
64 OAD 0.43609 0.92
65 ATP 0.435484 0.945205
66 OOB 0.435115 0.958904
67 B4P 0.434426 0.945205
68 AP5 0.434426 0.945205
69 GAP 0.433071 0.92
70 0WD 0.432432 0.922078
71 5FA 0.432 0.945205
72 2A5 0.432 0.87013
73 AQP 0.432 0.945205
74 00A 0.428571 0.909091
75 CA0 0.427419 0.92
76 ALF ADP 0.426357 0.871795
77 ADP ALF 0.426357 0.871795
78 ACP 0.424 0.92
79 NAJ PZO 0.423841 0.897436
80 9SN 0.423358 0.897436
81 VO4 ADP 0.423077 0.932432
82 ANP MG 0.423077 0.896104
83 ADP VO4 0.423077 0.932432
84 WAQ 0.422222 0.884615
85 ACQ 0.421875 0.92
86 V3L 0.421875 0.945205
87 ADQ 0.421053 0.92
88 AR6 0.420635 0.918919
89 APR 0.420635 0.918919
90 ATP A A A 0.42029 0.958333
91 CO7 0.419753 0.786517
92 1ZZ 0.419118 0.841463
93 3OD 0.419118 0.92
94 DLL 0.41791 0.958904
95 AD9 0.417323 0.92
96 NAX 0.416667 0.875
97 OVE 0.416667 0.857143
98 MYR AMP 0.416058 0.841463
99 AV2 0.415385 0.868421
100 A3P 0.414634 0.944444
101 NNR 0.414414 0.72973
102 ALF ADP 3PG 0.413793 0.8625
103 OMR 0.413793 0.831325
104 LA8 ALF 3PG 0.413793 0.8625
105 ANP 0.410853 0.92
106 A1R 0.410448 0.860759
107 ABM 0.409836 0.893333
108 AMP 0.408333 0.944444
109 A 0.408333 0.944444
110 SON 0.408 0.933333
111 PPS 0.407692 0.829268
112 5AL 0.407692 0.932432
113 TYR AMP 0.407143 0.933333
114 NAI 0.406897 0.909091
115 7D3 0.406504 0.857143
116 DAL AMP 0.406015 0.932432
117 ADX 0.404762 0.829268
118 ATF 0.40458 0.907895
119 3UK 0.404412 0.945946
120 AMP DBH 0.404255 0.894737
121 139 0.402685 0.875
122 AMP MG 0.401639 0.893333
123 50T 0.401575 0.906667
124 SRP 0.401515 0.907895
125 A A 0.40146 0.972222
126 FA5 0.4 0.933333
127 3AM 0.4 0.90411
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1TLL; Ligand: NAP; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 1tll.bio1) has 26 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 2; Query (leader) PDB : 1TLL; Ligand: FMN; Similar sites found: 100
This union binding pocket(no: 2) in the query (biounit: 1tll.bio1) has 25 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 4KCT FDP 0.001171 0.45941 1.002
2 1CT9 GLN 0.02435 0.40343 1.08499
3 4B2D FBP 0.001949 0.43972 1.09489
4 3RC3 ANP 0.02229 0.40538 1.32939
5 4AMV F6R 0.006732 0.41499 1.47783
6 4IP7 FBP 0.001162 0.45004 1.65746
7 2VVG ADP 0.03771 0.40222 1.71429
8 1LYX PGA 0.006873 0.41841 2.01613
9 1D6Z HY1 0.01975 0.41424 2.03488
10 2VGK REZ 0.02675 0.40178 2.04499
11 1RYO OXL 0.02606 0.41902 2.14067
12 2WHX ADP 0.03544 0.40089 2.26537
13 4PPF FLC 0.006704 0.44533 2.28571
14 3DC4 ADP 0.02187 0.41002 2.32558
15 2ZJ3 G6P 0.006672 0.40476 2.4
16 4AVB CMP 0.0188 0.40135 2.4024
17 2IZ1 ATR 0.02095 0.41067 2.74262
18 1BG2 ADP 0.02074 0.41601 2.76923
19 1T5B FMN 0.00221 0.42918 2.98507
20 2OQ5 BEN 0.03189 0.40362 3.01724
21 2O2C G6Q 0.0002753 0.47872 3.09951
22 1A0J BEN 0.036 0.40029 3.13901
23 1KOJ PAN 0.0005661 0.4509 3.2316
24 2OHH FMN 0.0005856 0.44231 3.46535
25 2FCR FMN 0.0000000008071 0.61563 3.48837
26 2PZE ATP 0.03218 0.40542 3.49345
27 3WCS MAN NAG 0.008218 0.43217 3.54331
28 3WCS MAN NAG GAL 0.01093 0.4168 3.54331
29 4B9E FAH 0.01831 0.41935 3.65448
30 3LRE ADP 0.03853 0.40164 3.66197
31 4PTZ FMN 0.001234 0.44447 3.66492
32 1MAI I3P 0.02721 0.40925 3.81679
33 1GMN IDS SGN IDS SGN IDS 0.03043 0.407 3.82514
34 4L8F MTX 0.03411 0.40171 3.84615
35 1L5Y BEF 0.002522 0.44338 3.87097
36 5K9B FMN 0.00000000001088 0.79406 3.88889
37 3QPB R1P 0.005877 0.4301 3.90071
38 3FGZ BEF 0.004405 0.42105 3.90625
39 1E5D FMN 0.000662 0.43641 3.9801
40 1SW0 PGA 0.008533 0.41793 4.03226
41 1X9I G6Q 0.006176 0.42469 4.06977
42 1MOQ GLP 0.006171 0.40955 4.07609
43 2Q9U FMN 0.00024 0.47155 4.10628
44 3BJE R1P 0.02783 0.40046 4.58453
45 1M6P M6P 0.02056 0.41142 4.60526
46 3HQP FDP 0.006202 0.42895 4.60922
47 1JJ7 ADP 0.01643 0.42339 4.61538
48 2AWN ADP 0.04047 0.40027 4.72441
49 3AIH BMA MAN MAN 0.03383 0.40227 4.83871
50 2CXS F6P 0.0006079 0.44552 4.8474
51 1TE2 PGA 0.01709 0.41448 4.86726
52 3LN9 FLC 0.0001459 0.5313 5.03597
53 4N82 FMN 0.000000437 0.59928 5.05618
54 2POC BG6 0.002333 0.44046 5.17711
55 2Z9C FMN 0.001627 0.43117 5.5
56 2J0B UDP 0.002637 0.45289 5.71429
57 4IF4 BEF 0.003793 0.43168 5.76923
58 3RGQ 5P5 0.02041 0.41397 5.76923
59 2IMG MLT 0.01953 0.41163 5.96026
60 1T5C ADP 0.02231 0.41337 6.30372
61 2BDG PBZ 0.02864 0.40584 7.17489
62 4OWK NGA 0.01437 0.40931 7.24638
63 1AG9 FMN 0.0000000002679 0.65733 7.42857
64 2OG7 AHB 0.0257 0.40698 7.56302
65 5TP0 BRN 0.02296 0.41131 7.58929
66 1T10 F6P 0.02488 0.40936 7.70349
67 5XVQ 8GC 0.02484 0.40661 7.74648
68 4LTN FMN 0.001684 0.43053 8.12183
69 4LTN NAI 0.002247 0.41815 8.12183
70 3KDM TES 0.005276 0.45018 8.44444
71 3GFS FMN 0.0008166 0.46693 8.62069
72 1CZR FMN 0.0000000001761 0.74096 8.87574
73 3N39 FMN 0.0000185 0.49941 9.15033
74 2VMG MBG 0.02413 0.40598 9.55414
75 2XBL M7P 0.006308 0.41629 9.59596
76 1G6H ADP 0.0112 0.434 10.1167
77 3S6X SIA GAL BGC 0.02096 0.40278 10.4615
78 1OBV FMN 0.0000000003363 0.71874 11.8343
79 1T0I FMN 0.00246 0.42713 12.0419
80 2BES RES 0.01229 0.41029 13.3721
81 5LJI FMN 0.0000003356 0.61234 14.1892
82 1RLJ FMN 0.0000003129 0.60579 18.705
83 2WC1 FMN 0.00000000001075 0.79429 19.7802
84 5NUL FMN 0.0001563 0.48473 20.2899
85 3IWD M2T 0.005699 0.44088 20.5882
86 4HEQ FMN 0.000000005914 0.60815 21.9178
87 4BMO FMN 0.000001273 0.53052 23.5294
88 3KAP FMN 0.0000003624 0.58147 23.8095
89 2XOD FMN 0.0000003569 0.58858 24.3697
90 1AKV FMN 0.00000003936 0.60775 24.4898
91 3F6R FMN 0.0000005229 0.53073 25.6757
92 1BVY FMN 0.000000001559 0.68122 40.3141
93 4OXX FMN 0.00000000009084 0.75358 45.0617
94 4H2D FMN 0.000000000002912 0.8192 46.6667
95 3FJO FMN 0.0000000001245 0.73731 46.7818
96 5GXU FMN 0.0000000000005078 0.75244 47.8125
97 1B1C FMN 0.0000000000004767 0.85371 48.0663
98 5FA6 FMN 0.0000000005655 0.76463 49.1909
99 5FA6 FAD 0.0000000005655 0.76463 49.1909
100 5FA6 NAP 0.0000000005991 0.76463 49.1909
Pocket No.: 3; Query (leader) PDB : 1TLL; Ligand: FAD; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 3) in the query (biounit: 1tll.bio1) has 21 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 4; Query (leader) PDB : 1TLL; Ligand: FMN; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 1tll.bio1) has 25 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 5; Query (leader) PDB : 1TLL; Ligand: NAP; Similar sites found: 47
This union binding pocket(no: 5) in the query (biounit: 1tll.bio1) has 27 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 4BWL MN9 0.0383 0.40138 1.97368
2 4JP3 CIT 0.02191 0.40099 2.09205
3 2IF8 ADP 0.03722 0.40064 2.75482
4 2D2F ADP 0.02724 0.40645 2.90698
5 4XDA RIB 0.01129 0.41909 3.05233
6 1IZC PYR 0.009911 0.42856 3.24484
7 4Z2S NDG 0.02802 0.40777 3.52113
8 4Z2S NAG 0.02802 0.40777 3.52113
9 1OFL NGK GCD 0.01339 0.42006 3.7422
10 1DMY AZM 0.02686 0.40407 4.43548
11 5N53 8NB 0.03248 0.40521 4.61538
12 1A5Z FBP 0.02034 0.42016 4.70219
13 2W5P CL8 0.03659 0.40172 5.36913
14 5HWK BEZ 0.01126 0.42968 5.41667
15 2NZ5 226 0.006636 0.41321 6.77966
16 3QDV NDG 0.02316 0.41269 9.09091
17 3QDW NDG 0.03208 0.40622 9.09091
18 3QDX CBS 0.03633 0.40287 9.09091
19 2WMC MGP 0.04041 0.42078 9.55056
20 3HY2 ATP 0.007308 0.43305 9.70874
21 1Y2W NAG 0.02666 0.4096 10.5634
22 3W2E NAD 0.0008332 0.44801 16.6052
23 3W2E FAD 0.0008332 0.44801 16.6052
24 1PVC ILE SER GLU VAL 0.01991 0.42175 17.6471
25 2OFE NAG 0.02708 0.40891 18.3099
26 2VNI FAD 0.0000253 0.42671 19.8529
27 2VNI A2P 0.0000253 0.42671 19.8529
28 3IWD M2T 0.02351 0.40429 20.5882
29 3CRZ NAP 0.0000125 0.44156 21.4008
30 1N13 AG2 0.02203 0.41511 23.0089
31 2QQC AG2 0.01462 0.42475 23.2143
32 5VW2 FDA 0.000000111 0.47334 28.481
33 5VW2 NAP 0.000000111 0.47334 28.481
34 1QFY FAD 0.000007529 0.5278 29.8701
35 1QFY NAP 0.000007529 0.45122 29.8701
36 3JQQ A2P 0.00003573 0.43602 31.0127
37 2XNJ NAP 0.000002917 0.55391 32.3308
38 1FND A2P 0.000005329 0.53078 32.4841
39 1FND FAD 0.000005329 0.46532 32.4841
40 2BSA NAP 0.0000002193 0.43365 32.6733
41 2BSA FAD 0.0000006426 0.42556 32.6733
42 2QTZ NAP 0.0000001082 0.50759 38.0334
43 3QFS FAD 0.00000002014 0.63788 43.2314
44 3QFS NAP 0.00000002014 0.51255 43.2314
45 5FA6 NAP 0.00000003565 0.66884 49.1909
46 5FA6 FAD 0.00000003384 0.66884 49.1909
47 5FA6 FMN 0.00000003384 0.66884 49.1909
Pocket No.: 6; Query (leader) PDB : 1TLL; Ligand: FAD; Similar sites found: 88
This union binding pocket(no: 6) in the query (biounit: 1tll.bio1) has 22 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1VJ7 GPX 0.02224 0.40293 2.29008
2 2CND FAD 0.0000009901 0.56156 2.59259
3 4NRT 2NG 0.02701 0.40575 2.6616
4 2EIX FAD 0.000005927 0.47164 2.88066
5 2PL3 ADP 0.02119 0.40173 2.9661
6 2Q3M MLA 0.0395 0.40347 3.37423
7 3BY9 SIN 0.03332 0.40137 3.46154
8 4G1V FAD 0.00000002308 0.65037 3.50877
9 2OG2 MLI 0.02702 0.41801 3.62117
10 3A3B FMN 0.001135 0.46512 4.21053
11 3A3B RBF 0.001272 0.46266 4.21053
12 3B9Q MLI 0.0298 0.41146 4.30464
13 3BMN AX3 0.01047 0.41614 4.51389
14 2ZJ5 ADP 0.01279 0.42012 4.79651
15 2PIA FMN 0.0000006271 0.56994 4.98442
16 1KQR MNA 0.005419 0.41843 5.02793
17 4Q3F TLA 0.01256 0.40634 5.12821
18 1EJE FMN 0.002484 0.42149 5.20833
19 3I7V B4P 0.001353 0.47531 5.22388
20 2R5A MLZ 0.007298 0.42473 5.28302
21 4YHB FAD 0.00001475 0.52333 5.49451
22 2P3I MNA 0.01227 0.40858 5.59006
23 1KZL CRM 0.001291 0.45686 6.73077
24 4RHS SIA SIA GAL 0.00985 0.41469 7.37705
25 1FWV SGA MAG FUC 0.02162 0.40296 7.46269
26 1NE7 16G 0.01244 0.41786 7.61246
27 4QVB F42 0.004516 0.4011 8.16327
28 3KDM TES 0.02091 0.40778 8.44444
29 4LO6 SIA GAL 0.0002059 0.49748 8.94737
30 3QDX CBS 0.02364 0.40944 9.09091
31 3QDV NDG 0.02434 0.40882 9.09091
32 3QDW NDG 0.02698 0.40551 9.09091
33 3QDY CBS 0.02749 0.40537 9.09091
34 4B4D FAD 0.00000003136 0.61209 9.16031
35 4DS0 A2G GAL NAG FUC 0.01202 0.41091 9.81595
36 1EP2 FAD 0.00007264 0.4598 9.96169
37 5E6O TRP GLU GLU LEU 0.007151 0.42533 10.1695
38 3RK0 AMP 0.01506 0.40113 13.9241
39 1A8P FAD 0.00000006822 0.61068 14.7287
40 3OZV FAD 0.00000007116 0.65762 14.8883
41 3OZV ECN 0.000001729 0.59881 14.8883
42 4WQM FAD 0.000000002181 0.68382 15.3374
43 1QX4 FAD 0.00000646 0.43125 15.6934
44 3UEC ALA ARG TPO LYS 0.02241 0.41107 16.4384
45 3W2E NAD 0.000001074 0.59871 16.6052
46 3W2E FAD 0.000001074 0.59871 16.6052
47 4F07 FAD 0.006234 0.40087 16.8421
48 3ZOD HQE 0.008734 0.40419 17.2775
49 5O0X FAD 0.000004218 0.57728 17.5258
50 1PVC ILE SER GLU VAL 0.005704 0.43799 17.6471
51 1KRH FAD 0.000000001672 0.67879 18.6391
52 4EOY ASN ASP TRP LEU LEU PRO SER TYR 0.01686 0.40263 19.5312
53 2VNI FAD 0.0000002242 0.46229 19.8529
54 2VNI A2P 0.0000002242 0.46229 19.8529
55 3CRZ FAD 0.00000002004 0.6198 21.4008
56 3CRZ NAP 0.0000001143 0.47431 21.4008
57 1N13 AG2 0.01254 0.41952 23.0089
58 2QQC AG2 0.01419 0.41702 23.2143
59 1J6W MET 0.01735 0.4122 27.4286
60 5VW2 FDA 0.000000005259 0.47137 28.481
61 5VW2 NAP 0.000000005259 0.47137 28.481
62 3VO1 FAD 0.000000000016 0.79902 29.2994
63 5H5J FAD 0.0000000003206 0.69656 29.7735
64 1QFY FAD 0.0000000008043 0.73384 29.8701
65 1QFY NAP 0.0000000008043 0.52286 29.8701
66 1GAW FAD 0.000000000007776 0.82634 30.8917
67 3JQQ A2P 0.00000002494 0.50371 31.0127
68 3JQQ FAD 0.00000003813 0.46981 31.0127
69 3MHP FAD 0.000000000154 0.73276 31.0811
70 4U9U FAD 0.000000003378 0.64997 31.3167
71 2RC5 FAD 0.000000002113 0.67448 31.5287
72 1SM4 FAD 0.00000000001404 0.80157 31.7568
73 2XNJ FAD 0.000004775 0.47926 32.3308
74 2XNJ NAP 0.0000009425 0.42411 32.3308
75 1FND A2P 0.000000001435 0.71808 32.4841
76 1FND FAD 0.000000001435 0.53088 32.4841
77 2BSA FAD 0.00000001103 0.42839 32.6733
78 2BSA NAP 0.00000001185 0.42395 32.6733
79 1EWY FAD 0.0000000001741 0.76402 35.9736
80 2QTZ FAD 0.00000000008683 0.75441 38.0334
81 2QTZ NAP 0.000000002838 0.51733 38.0334
82 3QFS FAD 0.0000000008957 0.73592 43.2314
83 3QFS NAP 0.0000000008957 0.50933 43.2314
84 3FJO FAD 0.0000000001081 0.7502 46.7818
85 5GXU FAD 0.00000000009056 0.75595 47.8125
86 5FA6 NAP 0.000000002947 0.75727 49.1909
87 5FA6 FAD 0.000000002798 0.75727 49.1909
88 5FA6 FMN 0.000000002798 0.75727 49.1909
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