Receptor
PDB id Resolution Class Description Source Keywords
1UPT 1.7 Å EC: 7.-.-.- STRUCTURE OF A COMPLEX OF THE GOLGIN-245 GRIP DOMAIN WITH AR HOMO SAPIENS HYDROLASE/PROTEIN-BINDING COMPLEX (GTPASE-GOLGIN) GOLGIN-2ARL1 GOLGIN GTPASE G-PROTEIN GOLGI GRIP DIMER PROTEINVESICLE TRAFFICKING HYDROLASE-PROTEIN-BINDING COMPLEX
Ref.: STRUCTURAL BASIS FOR ARL1-DEPENDENT TARGETING OF HO GRIP DOMAINS TO THE GOLGI APPARATUS MOL.CELL V. 12 863 2003
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GTP A:1182;
C:1181;
E:1181;
G:1181;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
submit data
523.18 C10 H16 N5 O14 P3 c1nc2...
MG A:1183;
C:1182;
E:1182;
G:1182;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
none;
none;
none;
none;
submit data
24.305 Mg [Mg+2...
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1UPT 1.7 Å EC: 7.-.-.- STRUCTURE OF A COMPLEX OF THE GOLGIN-245 GRIP DOMAIN WITH AR HOMO SAPIENS HYDROLASE/PROTEIN-BINDING COMPLEX (GTPASE-GOLGIN) GOLGIN-2ARL1 GOLGIN GTPASE G-PROTEIN GOLGI GRIP DIMER PROTEINVESICLE TRAFFICKING HYDROLASE-PROTEIN-BINDING COMPLEX
Ref.: STRUCTURAL BASIS FOR ARL1-DEPENDENT TARGETING OF HO GRIP DOMAINS TO THE GOLGI APPARATUS MOL.CELL V. 12 863 2003
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 250 families.
1 1UPT - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 217 families.
1 1UPT - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 181 families.
1 1UPT - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GTP; Similar ligands found: 147
No: Ligand ECFP6 Tc MDL keys Tc
1 GTP 1 1
2 GP3 0.921053 0.973684
3 GDP 0.909091 1
4 GSP 0.853659 0.948718
5 GNH 0.82716 0.986667
6 G1R 0.819277 0.986667
7 GAV 0.811765 0.961039
8 GNP 0.809524 0.973684
9 GCP 0.797619 0.973684
10 5GP 0.797468 0.986486
11 G 0.797468 0.986486
12 GMV 0.764706 0.973684
13 G2R 0.764045 0.961039
14 G5P 0.755319 0.973684
15 GTG 0.752688 0.936709
16 G2P 0.747126 0.961039
17 G3A 0.744681 0.973684
18 GDD 0.741935 0.961039
19 GKE 0.741935 0.961039
20 GDC 0.741935 0.961039
21 0O2 0.736264 0.986486
22 GP2 0.729412 0.961039
23 6CK 0.726316 0.936709
24 Y9Z 0.723404 0.902439
25 GPG 0.717391 0.961039
26 GFB 0.715789 0.961039
27 GDR 0.715789 0.961039
28 GDP MG 0.712644 0.923077
29 GDP BEF 0.704545 0.9
30 GPD 0.704082 0.925
31 JB2 0.693878 0.961039
32 GKD 0.693878 0.961039
33 GCP G 0.692308 0.935065
34 GDX 0.686869 0.973684
35 ALF 5GP 0.685393 0.888889
36 GTP MG 0.681319 0.923077
37 BEF GDP 0.681319 0.888889
38 GH3 0.681319 0.973333
39 YGP 0.677083 0.901235
40 G3D 0.67033 0.986486
41 GDP AF3 0.659574 0.888889
42 GDP ALF 0.659574 0.888889
43 DGT 0.659341 0.923077
44 GMP 0.658228 0.88
45 G4P 0.655914 0.986486
46 JB3 0.653846 0.948718
47 NGD 0.647619 0.961039
48 CAG 0.642202 0.880952
49 2MD 0.62963 0.891566
50 G G 0.622449 0.935065
51 MGP 0.619565 0.961039
52 U2G 0.616822 0.936709
53 6G0 0.612903 0.961039
54 MGD 0.612613 0.891566
55 TPG 0.608696 0.840909
56 CG2 0.605505 0.936709
57 GDP 7MG 0.601942 0.911392
58 FEG 0.601852 0.879518
59 ZGP 0.59633 0.869048
60 MD1 0.591304 0.891566
61 PGD 0.591304 0.925
62 3GP 0.590909 0.946667
63 GPX 0.581633 0.946667
64 DGI 0.580645 0.923077
65 IDP 0.576087 0.972973
66 DBG 0.567797 0.948718
67 FE9 0.555556 0.776596
68 2GP 0.555556 0.96
69 G4M 0.547619 0.880952
70 BGO 0.544643 0.924051
71 I2C FE2 CMO CMO 0.538462 0.808989
72 ATP 0.537634 0.92
73 G1G 0.533898 0.925
74 AQP 0.531915 0.92
75 5FA 0.531915 0.92
76 G A A A 0.525862 0.923077
77 U A G G 0.521368 0.935065
78 01G 0.518868 0.902439
79 ITT 0.510638 0.868421
80 P2G 0.510638 0.883117
81 GGM 0.504274 0.901235
82 G1R G1R 0.504065 0.924051
83 DGP 0.5 0.910256
84 PGD O 0.5 0.850575
85 MGO 0.5 0.864198
86 P1G 0.5 0.871795
87 DG 0.5 0.910256
88 GTA 0.495495 0.936709
89 B4P 0.489362 0.894737
90 AP5 0.489362 0.894737
91 IMP 0.489362 0.959459
92 7DT 0.484536 0.906667
93 G G U 0.482143 0.935065
94 GPC 0.479339 0.879518
95 G C 0.478992 0.9
96 BA3 0.478723 0.894737
97 ADP 0.473684 0.92
98 G2Q 0.471698 0.961039
99 G7M 0.46875 0.948052
100 25L 0.458716 0.907895
101 A2D 0.457447 0.894737
102 RGT 0.45045 0.909091
103 AGS 0.45 0.873418
104 SAP 0.45 0.873418
105 SGP 0.44898 0.82716
106 U G A 0.448529 0.888889
107 A4P 0.445378 0.869048
108 G G G RPC 0.442623 0.875
109 ACQ 0.441176 0.896104
110 ANP 0.441176 0.896104
111 8GT 0.441176 0.875
112 APC G U 0.44 0.886076
113 G U34 0.438017 0.888889
114 6AD 0.436893 0.841463
115 G G G C 0.433071 0.9125
116 UP5 0.432203 0.873418
117 35G 0.431373 0.933333
118 C2E 0.431373 0.921053
119 PCG 0.431373 0.933333
120 A G C C 0.429688 0.911392
121 5GP 5GP 0.427184 0.883117
122 TAT 0.427184 0.884615
123 APR 0.425743 0.894737
124 AR6 0.425743 0.894737
125 AN2 0.424242 0.907895
126 7DD 0.424242 0.906667
127 DG DG 0.423423 0.865854
128 AD9 0.421569 0.896104
129 M33 0.42 0.883117
130 7D4 0.42 0.835443
131 UCG 0.419847 0.911392
132 H6Y 0.419048 0.946667
133 G C C C 0.416667 0.924051
134 ACP 0.415842 0.896104
135 T5A 0.414634 0.802326
136 MGQ 0.412844 0.935897
137 ADQ 0.412844 0.871795
138 A1R 0.412844 0.839506
139 MGT 0.411215 0.823529
140 A G U 0.410072 0.888889
141 93A 0.41 0.833333
142 A22 0.407407 0.907895
143 CA0 0.405941 0.896104
144 ATF 0.40566 0.884615
145 AGO 0.404762 0.888889
146 MGV 0.401786 0.890244
147 CGP 0.4 0.86747
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1UPT; Ligand: GTP; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 1upt.bio1) has 21 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 2; Query (leader) PDB : 1UPT; Ligand: GTP; Similar sites found: 535
This union binding pocket(no: 2) in the query (biounit: 1upt.bio1) has 23 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1ZC3 GNP 0.0000000002241 0.72315 None
2 3DDC GNP 0.00000000002351 0.68533 None
3 1CLU DBG 0.00000001049 0.68275 None
4 3KUD GDP 0.000000006456 0.6573 None
5 1U8Z GDP 0.000000003566 0.64455 None
6 2CBZ ATP 0.000002337 0.63144 None
7 3EC1 GDP 0.00000001012 0.57647 None
8 4YDS ATP 0.00003904 0.54809 None
9 5KUT GDP 0.0000001121 0.5383 None
10 1M0S CIT 0.01045 0.41884 None
11 1PTR PRB 0.01704 0.41565 None
12 1T8U UAP SGN IDS SGN 0.009817 0.41195 None
13 2IL4 COA 0.008459 0.40713 None
14 1YQC GLV 0.01239 0.40448 None
15 1LOJ U 0.03274 0.40002 None
16 2BES RES 0.01506 0.40283 1.16959
17 3DKP ADP 0.0002207 0.49619 1.75439
18 3R96 AMP 0.00799 0.41387 1.75439
19 3R96 ACO 0.00799 0.41387 1.75439
20 3IO3 ADP 0.00001821 0.49039 2.29885
21 3VX3 ADP 0.0001272 0.47947 2.33918
22 2CHG ANP 0.0007376 0.45068 2.33918
23 3EWA ANP 0.00003694 0.43603 2.33918
24 1ZX5 LFR 0.0281 0.40962 2.33918
25 4K81 GTP 0.00000000002481 0.67092 2.92398
26 4H1V GNP 0.000007603 0.53887 2.92398
27 2BEK ATP 0.0009969 0.4327 2.92398
28 1G8S MET 0.009155 0.42688 2.92398
29 2ZE7 DST 0.00225 0.42485 2.92398
30 4JBL MET 0.01244 0.41959 2.92398
31 1LFD GNP 0.00000000001615 0.76842 3.44828
32 1SVI GDP 0.00000002436 0.70027 3.50877
33 1V8K ANP 0.0000006193 0.62046 3.50877
34 3EZ2 ADP 0.0002346 0.5013 3.50877
35 2JLR ANP 0.0001027 0.44605 3.50877
36 2F3R G5P 0.004168 0.42046 3.50877
37 4CR6 MAN 0.01846 0.40642 3.50877
38 2FFQ GSP 0.00000000001851 0.76928 4.09357
39 2RCN GDP 0.0000000003299 0.60604 4.09357
40 1JJV ATP 0.00001939 0.56907 4.09357
41 1FP6 ADP 0.0001061 0.4935 4.09357
42 4V03 ADP 0.00002341 0.46131 4.09357
43 2OZE AGS 0.0004211 0.45689 4.09357
44 5VGR GDP 0.0006327 0.45364 4.09357
45 5LTJ ADP 0.00008792 0.43156 4.09357
46 2XAU ADP 0.0002187 0.42499 4.09357
47 1W5T ADP 0.004382 0.4163 4.09357
48 1W5T ANP 0.00355 0.41309 4.09357
49 4IHQ ADP 0.0001931 0.4042 4.09357
50 2C5L GTP 0.00000000001385 0.69348 4.62428
51 5GOE GDP 0.000000001844 0.72017 4.67836
52 1D2E GDP 0.00000003113 0.65377 4.67836
53 1XP8 AGS 0.0000817 0.52419 4.67836
54 4IDN GNP 0.00003194 0.49499 4.67836
55 1ZUI SKM 0.00003858 0.41293 4.7619
56 3LRE ADP 0.0000002386 0.68518 5
57 4NON GDP 0.0000001453 0.5373 5
58 1P4V GLY 0.01196 0.42345 5
59 5E95 GDP 0.00000002669 0.64781 5.15464
60 2UZI GTP 0.00000000003377 0.75484 5.26316
61 1SKQ GDP 0.00000000201 0.75439 5.26316
62 1XKV ATP 0.000042 0.51789 5.26316
63 5H56 TYD 0.00003344 0.50837 5.26316
64 5H56 ADP 0.00003344 0.50837 5.26316
65 2PL3 ADP 0.0001919 0.50567 5.26316
66 3FKQ ATP 0.0001039 0.48846 5.26316
67 1YTM ATP 0.0003234 0.45738 5.26316
68 1KO8 6PG 0.0002233 0.44664 5.26316
69 1CR1 TTP 0.0005456 0.43789 5.26316
70 3QXC ATP 0.000391 0.42474 5.26316
71 4PX9 ADP 0.0001104 0.41658 5.26316
72 4WOP CTP 0.00006025 0.47739 5.33333
73 4PPF FLC 0.0000005577 0.6714 5.84795
74 3IIJ ADP 0.00000102 0.60991 5.84795
75 2ZR9 DTP 0.00003545 0.53487 5.84795
76 2OBM ADP 0.0006032 0.49527 5.84795
77 4R43 GDP 0.0003102 0.48899 5.84795
78 4XGU ADP 0.0001575 0.48045 5.84795
79 3KJI ADP 0.0000209 0.47404 5.84795
80 2FAH GDP 0.0007483 0.45499 5.84795
81 1RRC ADP 0.0000003141 0.45221 5.84795
82 1NJF ADP 0.000247 0.44505 5.84795
83 1NJF AGS 0.0005407 0.44378 5.84795
84 4JLV ADP 0.00007909 0.42012 5.84795
85 2J5V PCA 0.02901 0.40748 5.84795
86 5MVR ADP 0.0000178 0.45489 6.17284
87 1G7S GDP 0.000000002884 0.72225 6.43275
88 5KSP GDP 0.0000005394 0.61428 6.43275
89 2D2F ADP 0.00003094 0.56188 6.43275
90 3ZFD ANP 0.0000001146 0.54626 6.43275
91 2XTN GTP 0.000002539 0.5315 6.43275
92 5KSZ GCP 0.000002212 0.50617 6.43275
93 5G41 AP5 0.0002862 0.4865 6.43275
94 4QOS ADP 0.0004338 0.47082 6.43275
95 3FB4 AP5 0.0004902 0.47025 6.43275
96 4MKF AP5 0.0008489 0.46073 6.43275
97 3FVQ ATP 0.0003254 0.45726 6.43275
98 1OXV ANP 0.000009132 0.44338 6.43275
99 4O48 ASP 0.01159 0.42359 6.43275
100 2JAQ DCP 0.001133 0.42279 6.43275
101 5J1S ATP 0.001378 0.41472 6.43275
102 5E5U MLI 0.01482 0.41327 6.43275
103 2HK9 ATR 0.01672 0.4045 6.43275
104 2F5X ASP 0.02548 0.40419 6.43275
105 2W2X GSP 0.0000000005321 0.68298 6.45161
106 1NVU GTP 0.00000000001499 0.77319 6.66667
107 1NVV GNP 0.00000000001533 0.69185 6.66667
108 3Q9L ATP 0.00004947 0.50277 6.66667
109 4LJ9 ACP 0.0005227 0.47796 6.66667
110 1VHT BA3 0.0003227 0.47679 6.66667
111 5K5Z ANP 0.0002757 0.46 6.66667
112 1ION ADP 0.00004887 0.45205 6.66667
113 4KFU ACP 0.000003599 0.44013 6.66667
114 1XMV ADP 0.00008846 0.43111 6.66667
115 4FCW ADP 0.0003977 0.41793 6.66667
116 4P32 ADP 0.0004581 0.44678 6.82731
117 3MD0 GDP 0.00000000002884 0.84645 7.01754
118 2ZFI ADP 0.000003209 0.58567 7.01754
119 2C04 GCP 0.000003427 0.55423 7.01754
120 1SQ5 ADP 0.00001311 0.54843 7.01754
121 4P4T GDP 0.00000497 0.54064 7.01754
122 2B8W ALF 5GP 0.000007301 0.5035 7.01754
123 5FTB ANP 0.0001422 0.49331 7.01754
124 5FHD ADP ALF 0.0001925 0.46697 7.01754
125 3CV2 OXL 0.03387 0.40017 7.01754
126 3Q85 GNP 0.0000000001166 0.61996 7.10059
127 1HTW ADP 0.00001148 0.46752 7.59494
128 4LC1 GDP 0.000000002466 0.73733 7.60234
129 1JJ7 ADP 0.0000003295 0.68359 7.60234
130 1G6H ADP 0.0000003698 0.68093 7.60234
131 3PQC GDP 0.000001238 0.58895 7.60234
132 3B5J 12D 0.00002689 0.55639 7.60234
133 2GDJ ANP 0.0001528 0.50397 7.60234
134 4MKG AP5 0.0005534 0.46789 7.60234
135 2WOJ ADP ALF 0.00003135 0.4629 7.60234
136 1FNN ADP 0.0003712 0.45926 7.60234
137 1OYY AGS 0.001665 0.45344 7.60234
138 2IXE ATP 0.0003203 0.45326 7.60234
139 4TMK T5A 0.001888 0.4368 7.60234
140 3FYH ADP 0.00106 0.4173 7.60234
141 3ZS9 ADP ALF 0.00002695 0.46535 7.89474
142 5HCN GCP 0.00000001125 0.69415 8.18713
143 5IRR GSP 0.00000001694 0.6315 8.18713
144 1X1R GDP 0.0000000008356 0.62875 8.18713
145 5L3V GDP 0.0000002854 0.61852 8.18713
146 2A9K GDP 0.000000007267 0.61328 8.18713
147 4R98 GNH 0.0000002037 0.52456 8.18713
148 1LVG ADP 0.0000002994 0.48029 8.18713
149 1OE0 TTP 0.003297 0.41776 8.18713
150 2QG6 NMN 0.0006344 0.41024 8.18713
151 2ZL4 ALA ALA ALA ALA 0.0274 0.40321 8.18713
152 4AG5 ADP 0.000001417 0.63099 8.33333
153 2VB6 ADP BEF 0.000006036 0.52761 8.33333
154 3E70 GDP 0.000000389 0.51944 8.33333
155 2VVG ADP 0.000000264 0.44522 8.33333
156 1L2T ATP 0.000439 0.43242 8.33333
157 1OFH ADP 0.0005385 0.41574 8.33333
158 1SES AMP 0.01828 0.40662 8.33333
159 2OG2 MLI 0.0000003169 0.68063 8.77193
160 3B9Q MLI 0.0000003025 0.67507 8.77193
161 1JWY GDP 0.000002346 0.5686 8.77193
162 4BQS ADP 0.00001283 0.55636 8.77193
163 5L3R GCP 0.0000003662 0.5536 8.77193
164 1JWY ADP 0.00002081 0.53889 8.77193
165 4BQS K2Q 0.0002163 0.48086 8.77193
166 1UJ2 C5P 0.0001665 0.43526 8.77193
167 1UJ2 ADP 0.0002982 0.4255 8.77193
168 2X7I CIT 0.006289 0.42528 8.77193
169 3TMK T5A 0.0001951 0.41878 8.77193
170 2XT3 ADP 0.0000008401 0.64993 9.35672
171 2ZTS ADP 0.0006052 0.45004 9.35672
172 4A4Z ANP 0.002145 0.44808 9.35672
173 3BD9 A3P 0.009987 0.41136 9.35672
174 1R0X ATP 0.0003265 0.40416 9.35672
175 1WQ1 AF3 0.0000001253 0.69083 9.94152
176 1WQ1 GDP 0.00000002244 0.61231 9.94152
177 1PUJ GNP 0.000000009028 0.59822 9.94152
178 1W0J ADP 0.0001663 0.44019 9.94152
179 4GOX A3P 0.001137 0.4239 9.94152
180 1W0J ADP BEF 0.001402 0.41632 9.94152
181 5H9I XAN 0.02361 0.40845 9.94152
182 1NY5 ADP 0.001892 0.40488 9.94152
183 3TK1 GDP 0.0000000001108 0.83254 10
184 4J0Q GDP 0.0000000004529 0.78671 10
185 2AWN ADP 0.0000001011 0.72508 10
186 1WDT GTP 0.0000000005098 0.71391 10
187 1YRB GDP 0.000000002598 0.70272 10
188 1T5C ADP 0.00000283 0.62363 10
189 5FG3 GDP 0.0000000002586 0.59511 10
190 3DEF GDP 0.000003347 0.5616 10
191 5L3S GNP 0.000001911 0.55102 10
192 5L3W GDP 0.000002529 0.50257 10
193 3T34 GDP 0.00001806 0.49643 10
194 4IOK ADP 0.0001598 0.4756 10
195 3B7G ANP 0.0004512 0.47539 10
196 4IOK XPO 0.0001202 0.4752 10
197 5X40 ACP 0.0001641 0.46747 10
198 5MZN ADP 0.001586 0.46557 10
199 1UKZ ADP 0.0008261 0.45252 10
200 3DZD ADP 0.001069 0.44796 10
201 4QRH 0O2 0.0004506 0.44081 10
202 4YMU ATP 0.0000182 0.4337 10
203 5IFS ADP 0.0001977 0.42976 10
204 4PJ3 ANP 0.003838 0.42275 10
205 1UJ5 5RP 0.01274 0.40631 10
206 2YOH WMJ 0.0002483 0.40598 10
207 3W6X HZP 0.03174 0.4015 10
208 4DSU GDP 0.00000000076 0.63022 10.0529
209 3COB ADP 0.0000007275 0.44723 10.5263
210 5HR5 ADP 0.0003591 0.43139 10.5263
211 5HR5 FLC 0.003608 0.42319 10.5263
212 3R7F CP 0.01469 0.41864 10.5263
213 1R6B ADP 0.0003721 0.41522 10.5263
214 1B0U ATP 0.0002672 0.47529 10.687
215 1F2U ATP 0.0004325 0.41951 10.7383
216 2KIN ADP 0.000001867 0.42099 11
217 1GOJ ADP 0.0000001235 0.70043 11.1111
218 5BQ5 ADP BEF 0.00008535 0.5036 11.1111
219 1U0J ADP 0.0005719 0.48197 11.1111
220 4E03 ADP 0.0000528 0.44642 11.1111
221 4U00 ADP 0.0000005894 0.42753 11.1111
222 4KVG GTP 0.00000000005746 0.74506 11.3095
223 3X1Z GNP 0.00000000003378 0.76136 11.3772
224 1NRJ GTP 0.00000000001942 0.74186 11.6667
225 3WXM GTP 0.00000000006929 0.74161 11.6667
226 4HI0 GDP 0.0000001162 0.6039 11.6667
227 4TTQ ATP 0.0000845 0.5165 11.6667
228 1IHU AF3 0.0001327 0.46922 11.6667
229 1IHU ADP 0.0001339 0.46056 11.6667
230 2C9O ADP 0.0004092 0.45303 11.6667
231 2QEN ADP 0.0001372 0.4488 11.6667
232 5I34 GDP 0.000159 0.4313 11.6667
233 1W7J ADP BEF 0.000001078 0.57652 11.6959
234 1LK7 DER 0.007119 0.41838 11.6959
235 1APZ ASP 0.00794 0.42963 11.7284
236 5LB3 ADP 0.000116 0.51658 12.2807
237 2ZPA ADP 0.0002927 0.44188 12.2807
238 1F9V ADP 0.000003719 0.43872 12.2807
239 2FNA ADP 0.0009068 0.43442 12.2807
240 2VOH CIT 0.01242 0.41667 12.7389
241 4D81 ADP 0.0002671 0.43109 12.8655
242 3A4M ADP 0.000000882 0.6325 13.3333
243 1YQT ADP 0.000007352 0.59282 13.3333
244 3Q72 GNP 0.0000000004976 0.58886 13.3333
245 2WHX ADP 0.00001043 0.58495 13.3333
246 4Q1A 2XZ 0.0006803 0.51775 13.3333
247 4Q1A UDP 0.0006803 0.51775 13.3333
248 4LYA ATP 0.00005836 0.51761 13.3333
249 4RZ3 ADP 0.00006861 0.46168 13.3333
250 1IN4 ADP 0.0005328 0.45245 13.3333
251 3QF7 ANP 0.0002715 0.44296 13.3333
252 3RC3 ANP 0.004275 0.4383 13.3333
253 3QKT ANP 0.0003496 0.43598 13.3333
254 4OI4 ATP 0.001674 0.41639 13.3333
255 4NZ6 DGL 0.02798 0.40296 13.3333
256 2ZJ5 ADP 0.03269 0.40036 13.3333
257 2NCD ADP 0.0000004117 0.65793 13.4503
258 2PEZ GGZ 0.00001458 0.52754 13.4503
259 2PEZ DAT 0.00001458 0.52754 13.4503
260 2IS6 ADP 0.000194 0.49892 13.4503
261 4XTR ATP 0.00007591 0.48151 13.4503
262 4XVU ATP 0.00008705 0.47902 13.4503
263 4XTR ADP 0.00009834 0.46151 13.4503
264 3RLF ANP 0.0003187 0.44539 13.4503
265 5M7P ADP 0.0009423 0.42215 13.4503
266 1JI0 ATP 0.000002494 0.60935 14.0351
267 3FWY ADP 0.00003232 0.47406 14.0351
268 1BG2 ADP 0.000001373 0.4252 14.0351
269 1NN5 ANP 0.0001218 0.41542 14.0351
270 1NN5 2DT 0.03517 0.40362 14.0351
271 3H86 AP5 0.0002634 0.47569 14.0625
272 2XTZ GSP 0.000000000009803 0.71345 14.6199
273 2IYL GDP 0.0000005179 0.62425 14.6199
274 2OFW ADX 0.00001461 0.53704 14.6199
275 4IEE AGS 0.000267 0.4985 14.6199
276 1X6V ADP 0.00005176 0.44089 14.6199
277 2CJW GDP 0.00000000007175 0.81214 15
278 3VMF GTP 0.00000000005005 0.7476 15
279 2HT6 GDP 0.00000000001614 0.62895 15
280 1MKY GDP 0.0000000002274 0.6086 15
281 5N69 ADP 0.00000353 0.56055 15
282 4PFO ADP 0.000005458 0.53409 15
283 5XDR ADP 0.000152 0.49785 15
284 3TBK ANP 0.0005126 0.49074 15
285 4WEI GLC GAL 0.004527 0.44921 15
286 3BER AMP 0.005061 0.42989 15
287 1D2N ANP 0.003749 0.41208 15
288 3BFX A3P 0.005433 0.4086 15
289 4HDO GNP 0.00000000001312 0.69395 15.2047
290 4HDQ GNP 0.0000000002346 0.64971 15.2047
291 3UIE ANP 0.00001677 0.5364 15.2047
292 2BIF ANP 0.0004195 0.46539 15.2047
293 2BIF SIN 0.0007491 0.46539 15.2047
294 5UQW GDP 0.0000000004224 0.70513 15.7895
295 2WKQ GTP 0.000000001112 0.66577 15.7895
296 5M04 GDP 0.0000000000532 0.61492 15.7895
297 1GUA GNP 0.00000000002114 0.68664 16.0494
298 3U6B GDP 0.0000000002439 0.80014 16.6667
299 2BVN GNP 0.00000000009986 0.76693 16.6667
300 4G5G GDP 0.0000000008376 0.76017 16.6667
301 2C77 GNP 0.000000000008968 0.75442 16.6667
302 2C78 GNP 0.00000000002353 0.7506 16.6667
303 3U6K GDP 0.000000001437 0.74876 16.6667
304 4PC3 GDP 0.00000001618 0.66667 16.6667
305 3NHB ADP 0.00000332 0.61188 16.6667
306 1D8T GDP 0.0000000005178 0.59893 16.6667
307 4P3Y GDP 0.0000000002065 0.59632 16.6667
308 5JBQ GDP 0.0000000006987 0.59546 16.6667
309 2HCJ GDP 0.0000000002932 0.59287 16.6667
310 4QM7 GTP 0.000002412 0.59171 16.6667
311 1G3Q ADP 0.000009542 0.55498 16.6667
312 4HSE ADP 0.0001629 0.49641 16.6667
313 2GK6 ADP 0.001573 0.46575 16.6667
314 4OHY ANP 0.00006512 0.46513 16.6667
315 4NCN GTP 0.00000000001338 0.74199 16.9591
316 4TMZ GSP 0.00000000002383 0.73201 16.9591
317 1DS6 GDP 0.00000001377 0.5584 16.9591
318 3CX8 GSP 0.00000000001211 0.66699 17.5439
319 1ZCB GDP 0.000000008018 0.65416 17.5439
320 4U5X GNP 0.000000001789 0.65043 17.5439
321 3AB3 GDP 0.00000006895 0.59649 17.5439
322 1Z6T ADP 0.0002857 0.46897 17.5439
323 5CK5 GDP 0.000000001267 0.57705 18.1287
324 3WY9 GDP 0.0000000002557 0.79911 18.3333
325 2QN6 GDP 0.000000000603 0.7805 18.3333
326 3WYA GDP 0.0000000005115 0.7706 18.3333
327 4RD0 GDP 0.00000000001653 0.75699 18.3333
328 4CVN ADP 0.000007493 0.58485 18.3333
329 1KK8 BEF ADP 0.00001055 0.53255 18.3333
330 1B7T ADP 0.00007678 0.50573 18.3333
331 3BOS CDP 0.0001982 0.49847 18.3333
332 1K6M AGS 0.0001705 0.45606 18.3333
333 3BP1 GUN 0.03756 0.40311 18.3333
334 4DKX GDP 0.0000000002648 0.78452 18.7134
335 1Y63 ADP 0.000001767 0.59829 18.7134
336 2J0V GDP 0.00000006393 0.54787 18.7134
337 1P9B GDP 0.0004388 0.46069 18.7134
338 1P9B HDA 0.02363 0.40523 18.7134
339 1YZQ GNP 0.00000000001151 0.69555 18.8235
340 1XTQ GDP 0.000000001393 0.68008 19.883
341 3T5G GDP 0.000000003979 0.5991 19.883
342 4B47 GDP 0.0000000001126 0.8169 20
343 4WZ6 ATP 0.000009203 0.58746 20
344 3KTA AP5 0.000294 0.4734 20
345 4FRZ ADP 0.000004161 0.43794 20
346 3H4S ADP 0.000001647 0.43569 20
347 2PZE ATP 0.000001349 0.4339 20
348 1XEX ATP 0.001598 0.40436 20
349 2BME GNP 0.000000000001664 0.81025 20.4678
350 4LX0 BEF GDP 0.000000000003779 0.79868 20.4678
351 1OIV GDP 0.000000002505 0.67557 20.4678
352 2ZEJ GDP 0.0000003538 0.53235 20.4678
353 1G6O ADP 0.00007289 0.50678 20.4678
354 1BO4 COA 0.004106 0.43433 20.4678
355 1NHX FTB 0.006676 0.4234 20.4678
356 1NHX PEP 0.01169 0.41142 20.4678
357 5UWP GNP 0.000000000003181 0.80528 21.0526
358 5UWR GNP 0.000000000002878 0.80372 21.0526
359 5UWU GNP 0.000000000002909 0.80352 21.0526
360 4HAT GNP 0.000000000003559 0.8032 21.0526
361 5UWS GNP 0.000000000003559 0.8032 21.0526
362 5UWI GNP 0.00000000000299 0.80302 21.0526
363 5UWT GNP 0.000000000003115 0.80226 21.0526
364 5DHF GNP 0.000000000003128 0.80218 21.0526
365 5DI9 GNP 0.000000000004314 0.79962 21.0526
366 3GJ8 GDP 0.0000000001828 0.77919 21.0526
367 3GJ5 GDP 0.000000000253 0.77248 21.0526
368 3CH5 GDP 0.000000000266 0.77145 21.0526
369 3GJ7 GDP 0.0000000006282 0.76626 21.0526
370 1Z0K GTP 0.000000000003812 0.76445 21.0526
371 3GJ0 GDP 0.0000000006902 0.76426 21.0526
372 3GJ4 GDP 0.0000000008114 0.76084 21.0526
373 1OIX GDP 0.0000000001562 0.72665 21.0526
374 5UWQ GNP 0.00000000000253 0.71761 21.0526
375 5UWO GNP 0.000000000002781 0.7162 21.0526
376 5UWW GNP 0.000000000002845 0.71591 21.0526
377 2HV8 GTP 0.0000000002912 0.71519 21.0526
378 5UWH GNP 0.000000000003044 0.71486 21.0526
379 5DIF GNP 0.000000000003203 0.71422 21.0526
380 5UWJ GNP 0.00000000000325 0.71398 21.0526
381 1IBR GNP 0.000000000006356 0.70436 21.0526
382 3RWO GDP 0.00000000607 0.65928 21.0526
383 1WA5 GTP 0.00000000001493 0.63873 21.0526
384 5BXQ GDP 0.000000000249 0.62773 21.0526
385 3GJ3 GDP 0.0000000005704 0.60159 21.0526
386 2D7C GTP 0.00000000006963 0.74152 21.5569
387 1CS4 GSP 0.00000000001896 0.67431 21.6374
388 1AZT GSP 0.00000000001874 0.661 21.6374
389 2QZ4 ADP 0.00005753 0.51156 21.6374
390 2CE7 ADP 0.000136 0.43439 21.6374
391 2Z48 NGA 0.01257 0.42981 21.6374
392 2Z49 AMG 0.03701 0.40312 21.6374
393 4ZKD GDP 0.00000000005386 0.74953 21.6667
394 1WF3 GNP 0.000000001175 0.69249 21.6667
395 1G7C 5GP 0.0000001263 0.65409 21.6667
396 2Q2Y MKR 0.0003152 0.47758 21.6667
397 2Q2Y ADP 0.0003428 0.47719 21.6667
398 2V7Q ATP 0.0001102 0.49846 22
399 2V7Q ADP 0.0004395 0.48162 22
400 2CK3 ANP 0.001503 0.43287 22
401 2CK3 ADP 0.001855 0.41512 22
402 3WYF GTP 0.000000000003004 0.80635 22.2222
403 3M1I GTP 0.000000000003482 0.80019 22.2222
404 1Z0F GDP 0.0000000001527 0.7829 22.2222
405 3WYG GTP 0.000000000003365 0.69867 22.2222
406 3REF GDP 0.00000001871 0.62971 22.2222
407 4D0G GTP 0.0000000007532 0.68786 22.807
408 3ZIA ATP 0.0001422 0.42828 23.1884
409 3ZIA ADP 0.0003638 0.42644 23.1884
410 3GJX GTP 0.000000000006977 0.78734 23.3333
411 2FJU GSP 0.000000000687 0.67907 23.3333
412 3SBD GNP 0.000000000429 0.65423 23.3333
413 5I0H ADP BEF 0.0000002704 0.57219 23.3333
414 1HE1 GDP 0.000001048 0.56327 23.3333
415 1HE1 AF3 0.00004233 0.54629 23.3333
416 1Z06 GNP 0.000000000001567 0.76159 23.3918
417 2G77 GDP 0.0000000001639 0.74597 23.3918
418 2G77 AF3 0.0000002674 0.66729 23.3918
419 3ZQ6 ADP ALF 0.00002295 0.5097 23.3918
420 1M7G ADX 0.00004252 0.50559 23.3918
421 1M7G ADP 0.00004195 0.50232 23.3918
422 1M7G AV2 0.000001549 0.47241 23.3918
423 1TAD ALF 0.0000000000673 0.75157 23.9766
424 1TAD GDP 0.0000000000673 0.75157 23.9766
425 2WJH GDP 0.000000005573 0.58712 24.0964
426 2WJH FLC 0.000002065 0.50397 24.0964
427 1CXZ GSP 0.0000000001031 0.72385 24.5614
428 2WIC GNP 0.000000003658 0.71734 24.5614
429 1GOT GDP 0.0000001875 0.58799 24.5614
430 5JCZ GDP 0.000000001315 0.69603 25
431 4ZG4 VO4 ADP 0.0000001648 0.59317 25
432 4WZA ADP 0.00003964 0.53922 25
433 4WZA ACP 0.00003964 0.53922 25
434 5IRN ADP 0.00006032 0.45501 25
435 1FQJ ALF 0.00000001451 0.73374 25.1462
436 1FQK ALF 0.00000004615 0.71453 25.1462
437 1M7B GTP 0.0000000007923 0.69605 25.1462
438 1GWN GTP 0.0000000005621 0.68244 25.1462
439 1FQJ GDP 0.00000002308 0.61206 25.1462
440 1FQK GDP 0.00000003469 0.60509 25.1462
441 2ODE ALF GDP 0.00000000003252 0.76515 25.731
442 1BH2 GSP 0.00000000003324 0.65333 25.731
443 2OM2 GDP 0.00000006704 0.61407 25.731
444 5KDO GDP 0.00000008017 0.61076 25.731
445 1Y3A GDP 0.00000003308 0.6059 25.731
446 1GP2 GDP 0.0000001491 0.57966 25.731
447 1SVK ALF GDP 0.000000000008348 0.79366 26.3158
448 1DAR GDP 0.0000000008922 0.75884 26.3158
449 3CNL GNP 0.000000005435 0.73281 26.3158
450 1KK1 GNP 0.000000001852 0.75616 26.6667
451 2WMO GTP 0.000000001106 0.73047 26.6667
452 4XOI GTP 0.0000000002216 0.71695 26.6667
453 1KMQ GNP 0.0000000001411 0.70179 26.6667
454 1YZN GNP 0.00000000001319 0.69416 26.6667
455 5JCP GDP ALF 0.000000003046 0.68964 26.6667
456 1TX4 ALF GDP 0.0000000006411 0.67568 26.6667
457 2NGR AF3 0.0000002362 0.66184 26.6667
458 2NGR GDP 0.00000006633 0.65754 26.6667
459 4YC7 GNP 0.000000004233 0.65661 26.6667
460 1A4R GNH 0.00000001844 0.65494 26.6667
461 1A4R GDP 0.00000001285 0.65304 26.6667
462 2BCG GDP 0.00000001765 0.64705 26.6667
463 1NF3 GNP 0.0000000007303 0.64607 26.6667
464 4XSH GSP 0.000000002416 0.64556 26.6667
465 4DID GDP 0.0000001268 0.64417 26.6667
466 1GRN AF3 0.0000005742 0.64206 26.6667
467 3LXR GDP 0.0000001849 0.62727 26.6667
468 1GRN GDP 0.000000131 0.61714 26.6667
469 1OW3 GDP 0.00000011 0.57141 26.6667
470 4D0N GDP 0.00000002745 0.54772 26.6667
471 4ITR GDP 0.0000009427 0.54212 26.6667
472 1QHG ATP 0.004816 0.41826 26.9006
473 2GJ8 ALF GDP 0.0000000007212 0.63189 27.4854
474 1QHH ATP 0.009997 0.41134 27.5449
475 1UAD GNP 0.00000000004768 0.74849 28.3333
476 2GCO GNP 0.00000000159 0.64065 28.3333
477 2GCN GDP 0.00000005499 0.61019 28.3333
478 5IRC GDP 0.0000002049 0.54344 28.3333
479 2DPY ADP 0.000125 0.52217 28.3333
480 3T12 GDP ALF 0.0000000001101 0.72266 29.8246
481 1R2Q GNP 0.000000000008372 0.61334 29.8246
482 3T1O GDP 0.00000003228 0.56797 29.8246
483 1G41 ADP 0.0002951 0.47859 30
484 2Y65 ADP 0.000004212 0.42715 30
485 3MJH GTP 0.000000000003579 0.73003 30.4094
486 2EFE GNH 0.000000006302 0.68525 30.4094
487 3E5H GNP 0.00000000006908 0.68229 32.1637
488 2FH5 GTP 0.00000000000414 0.79312 33.3333
489 2EW1 GNP 0.00000000001169 0.76711 33.3333
490 1MH1 GNP 0.0000000001151 0.73548 33.3333
491 1I4D GDP 0.00000006451 0.67915 33.3333
492 1E96 GTP 0.0000000004131 0.65504 33.3333
493 1RYH GNP 0.000000001213 0.61945 33.3333
494 5HPY GDP 0.0000000977 0.57293 33.3333
495 1G4U GDP 0.000003281 0.54847 33.3333
496 1F5N GNP 0.000006444 0.48845 33.3333
497 1G4U AF3 0.0005353 0.48736 33.3333
498 1YVD GNP 0.000000000009201 0.71643 35.6725
499 1VG8 GNP 0.00000000000426 0.79647 36.2573
500 1Z0J GTP 0.000000000004706 0.7112 36.2573
501 1VG1 GDP 0.0000000002535 0.6227 36.2573
502 1VG9 GDP 0.0000000004129 0.61798 36.2573
503 1VG0 GDP 0.000000003657 0.61195 36.2573
504 2A5J GDP 0.000000001643 0.7225 37.4269
505 1KAO GDP 0.00000002519 0.64892 37.7246
506 2WJG GDP 0.000000003298 0.73118 38.0117
507 2F9L GDP 0.00000002876 0.60795 38.0117
508 2Y8E GNP 0.00000000001959 0.70132 38.5965
509 1Z0A GDP 0.0000000002173 0.64302 38.5965
510 1G16 GDP 0.00000002364 0.62547 38.8235
511 5WDR GNP 0.00000000001311 0.77567 39.1813
512 1Z08 GNP 0.00000002833 0.60893 39.1813
513 3A1S GDP 0.000003211 0.57746 39.1813
514 3CPJ GDP 0.00000002031 0.58592 39.7661
515 1EK0 GNP 0.000000000005345 0.72403 40
516 1KY3 GDP 0.000000001037 0.63261 40.3509
517 3RAB GNP 0.00000000001868 0.76574 40.9357
518 1S8F GDP 0.0000000001952 0.64034 40.9357
519 1Z2A GDP 0.0000000401 0.60229 40.9357
520 5WRJ A3P 0.0043 0.40966 41.6667
521 3W5J GDP 0.0000002345 0.67469 42.6901
522 3TNF GNP 0.00000000001052 0.78304 43.2749
523 3QBT GNP 0.00000000000134 0.74564 43.2749
524 3SFV GDP 0.00000001001 0.6302 43.2749
525 4C4P GNP 0.00000000005418 0.74941 43.3333
526 5SZH GNP 0.000000000008762 0.78312 43.8596
527 4DCT GDP 0.000000002669 0.72385 43.8596
528 3TKL GTP 0.00000000002764 0.71244 43.8596
529 3NKV GNP 0.00000000003367 0.69345 43.8596
530 4LHW GNP 0.0000000001793 0.66764 44.4444
531 5J1J ANP 0.00007082 0.48278 45
532 3BC1 GNP 0.00000000003477 0.69329 45.614
533 1F6B GDP 0.0000000005748 0.75554 46.1988
534 1M2O GNP 0.00000000001122 0.77512 47.9532
535 2QTV GNP 0.000000000003828 0.79125 48.503
Pocket No.: 3; Query (leader) PDB : 1UPT; Ligand: GTP; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 3) in the query (biounit: 1upt.bio2) has 21 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 4; Query (leader) PDB : 1UPT; Ligand: GTP; Similar sites found: 19
This union binding pocket(no: 4) in the query (biounit: 1upt.bio2) has 22 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 2PKA BEN 0.02754 0.40036 None
2 2ZE7 AMP 0.007132 0.40508 2.92398
3 2D7D ADP 0.0009652 0.40089 4.09357
4 1FWV SGA MAG FUC 0.02005 0.41148 4.47761
5 1O8B ABF 0.007603 0.424 4.67836
6 1RJ9 GCP 0.000004117 0.40487 7.01754
7 2JBH 5GP 0.02027 0.4027 7.60234
8 1QF5 RPL 0.008429 0.45369 8.33333
9 4LO2 GAL BGC 0.02845 0.40145 10
10 4PU6 ASP 0.004916 0.43852 10.687
11 1ZOY UQ1 0.02086 0.40479 10.7143
12 4A6F SEP 0.01247 0.40502 10.8333
13 3W8X FAD 0.02368 0.4027 11.6667
14 5WRI A3P 0.005991 0.4034 18.3333
15 2Z48 A2G 0.01481 0.42295 21.6374
16 5G3U FDA 0.01745 0.4035 22.807
17 5G3U ITW 0.02624 0.4006 22.807
18 1RSG FAD 0.02096 0.40348 40
19 1YY5 FAD 0.02296 0.40333 46.6667
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