Receptor
PDB id Resolution Class Description Source Keywords
1UU1 2.38 Å EC: 2.6.1.9 COMPLEX OF HISTIDINOL-PHOSPHATE AMINOTRANSFERASE (HISC) FROM THERMOTOGA MARITIMA (APO-FORM) THERMOTOGA MARITIMA HISTIDINE BIOSYNTHESIS TRANSFERASE AMINOTRANSFERASE PYRIDPHOSPHATE
Ref.: STRUCTURAL STUDIES OF THE CATALYTIC REACTION PATHWA HYPERTHERMOPHILIC HISTIDINOL-PHOSPHATE AMINOTRANSFE J.BIOL.CHEM. V. 279 21478 2004
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
PMP HSA A:1335;
B:1335;
C:1335;
D:1335;
 Valid;
Valid;
Valid;
Valid;
 none;
none;
none;
none;
 submit data
446.249 n/a P(=O)...
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1UU1 2.38 Å EC: 2.6.1.9 COMPLEX OF HISTIDINOL-PHOSPHATE AMINOTRANSFERASE (HISC) FROM THERMOTOGA MARITIMA (APO-FORM) THERMOTOGA MARITIMA HISTIDINE BIOSYNTHESIS TRANSFERASE AMINOTRANSFERASE PYRIDPHOSPHATE
Ref.: STRUCTURAL STUDIES OF THE CATALYTIC REACTION PATHWA HYPERTHERMOPHILIC HISTIDINOL-PHOSPHATE AMINOTRANSFE J.BIOL.CHEM. V. 279 21478 2004
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 1UU1 - PMP HSA n/a n/a
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 1UU1 - PMP HSA n/a n/a
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 1UU1 - PMP HSA n/a n/a
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: PMP HSA; Similar ligands found: 9
No: Ligand ECFP6 Tc MDL keys Tc
1 PMP HSA 1 1
2 PLP HSA 0.46875 0.90625
3 PLP PMP 0.455696 0.777778
4 CKT 0.422222 0.761194
5 PLP BH2 0.419355 0.735294
6 PLP 2KZ 0.413043 0.746269
7 PLP SER 0.411111 0.746269
8 PLP 2TL 0.408602 0.735294
9 ASP PLP 0.404255 0.777778
Similar Ligands (3D)
Ligand no: 1; Ligand: PMP HSA; Similar ligands found: 0
No: Ligand Similarity coefficient
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1UU1; Ligand: PMP HSA; Similar sites found with APoc: 4
This union binding pocket(no: 1) in the query (biounit: 1uu1.bio2) has 23 residues
No: Leader PDB Ligand Sequence Similarity
1 1LC8 33P 31.0448
2 4R5Z SIN 48.3582
3 4R5Z PMP 48.3582
4 4R5Z PMP 48.3582
Pocket No.: 2; Query (leader) PDB : 1UU1; Ligand: PMP HSA; Similar sites found with APoc: 4
This union binding pocket(no: 2) in the query (biounit: 1uu1.bio2) has 24 residues
No: Leader PDB Ligand Sequence Similarity
1 2X5F PLP 7.16418
2 4R5Z PMP 48.3582
3 4R5Z SIN 48.3582
4 4R5Z PMP 48.3582
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