Receptor
PDB id Resolution Class Description Source Keywords
1UWZ 1.99 Å EC: 3.5.4.5 BACILLUS SUBTILIS CYTIDINE DEAMINASE WITH AN ARG56 - ALA SUB BACILLUS SUBTILIS CYTIDINE DEAMINASE CDD TETRAMER ZINC BINDING PYRIMIDINE METABOLISM SALVAGE HYDROLASE
Ref.: STRUCTURAL, KINETIC, AND MUTATIONAL STUDIES OF THE ENVIRONMENT IN TETRAMERIC CYTIDINE DEAMINASE BIOCHEMISTRY V. 43 6020 2004
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
THU A:138;
B:138;
Valid;
Valid;
none;
none;
submit data
230.218 C9 H14 N2 O5 C1CN(...
ZN A:1131;
B:1131;
Part of Protein;
Part of Protein;
none;
none;
submit data
65.409 Zn [Zn+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1UWZ 1.99 Å EC: 3.5.4.5 BACILLUS SUBTILIS CYTIDINE DEAMINASE WITH AN ARG56 - ALA SUB BACILLUS SUBTILIS CYTIDINE DEAMINASE CDD TETRAMER ZINC BINDING PYRIMIDINE METABOLISM SALVAGE HYDROLASE
Ref.: STRUCTURAL, KINETIC, AND MUTATIONAL STUDIES OF THE ENVIRONMENT IN TETRAMERIC CYTIDINE DEAMINASE BIOCHEMISTRY V. 43 6020 2004
Members (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 1UX1 - THU C9 H14 N2 O5 C1CN(C(=O)....
2 1JTK - THU C9 H14 N2 O5 C1CN(C(=O)....
3 1UX0 - THU C9 H14 N2 O5 C1CN(C(=O)....
4 1UWZ - THU C9 H14 N2 O5 C1CN(C(=O)....
70% Homology Family (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 1UX1 - THU C9 H14 N2 O5 C1CN(C(=O)....
2 1JTK - THU C9 H14 N2 O5 C1CN(C(=O)....
3 1UX0 - THU C9 H14 N2 O5 C1CN(C(=O)....
4 1UWZ - THU C9 H14 N2 O5 C1CN(C(=O)....
50% Homology Family (8)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 1UX1 - THU C9 H14 N2 O5 C1CN(C(=O)....
2 1JTK - THU C9 H14 N2 O5 C1CN(C(=O)....
3 1UX0 - THU C9 H14 N2 O5 C1CN(C(=O)....
4 1UWZ - THU C9 H14 N2 O5 C1CN(C(=O)....
5 2FR6 - URI C9 H12 N2 O6 C1=CN(C(=O....
6 1ZAB - URD C10 H13 N O6 C1C(=O)C=C....
7 2FR5 - TYU C9 H16 N2 O6 C1CN(C(=O)....
8 1MQ0 - BRD C10 H14 N2 O5 C1=CNC(=O)....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: THU; Similar ligands found: 4
No: Ligand ECFP6 Tc MDL keys Tc
1 THU 1 1
2 UMC 0.666667 0.852941
3 DUR 0.428571 0.935484
4 H2U 0.4 0.8
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1UWZ; Ligand: THU; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 1uwz.bio1) has 36 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 2; Query (leader) PDB : 1UWZ; Ligand: THU; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 1uwz.bio1) has 36 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 3; Query (leader) PDB : 1UWZ; Ligand: THU; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 3) in the query (biounit: 1uwz.bio1) has 36 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 4; Query (leader) PDB : 1UWZ; Ligand: THU; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 1uwz.bio1) has 36 residues
No: Leader PDB Ligand Sequence Similarity
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