Receptor
PDB id Resolution Class Description Source Keywords
1VG0 2.2 Å NON-ENZYME: TRANSPORT THE CRYSTAL STRUCTURES OF THE REP-1 PROTEIN IN COMPLEX WITH MONOPRENYLATED RAB7 PROTEIN RATTUS NORVEGICUS RAB PRENYLATION POST-TRANSLATIONAL MODIFICATION PROTEIN BINDING/PROTEIN TRANSPORT COMPLEX
Ref.: STRUCTURE OF THE RAB7:REP-1 COMPLEX: INSIGHTS INTO THE MECHANISM OF RAB PRENYLATION AND CHOROIDEREMIA DISEASE CELL(CAMBRIDGE,MASS.) V. 117 749 2004
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
CL A:3001;
Invalid;
none;
submit data
35.453 Cl [Cl-]
GDP B:1557;
Valid;
none;
submit data
443.201 C10 H15 N5 O11 P2 c1nc2...
GER A:952;
Valid;
none;
Kd = 0.8 nM
274.484 C20 H34 CC=C(...
MG B:3000;
Part of Protein;
none;
submit data
24.305 Mg [Mg+2...
PG4 B:5502;
Invalid;
none;
submit data
194.226 C8 H18 O5 C(COC...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1VG0 2.2 Å NON-ENZYME: TRANSPORT THE CRYSTAL STRUCTURES OF THE REP-1 PROTEIN IN COMPLEX WITH MONOPRENYLATED RAB7 PROTEIN RATTUS NORVEGICUS RAB PRENYLATION POST-TRANSLATIONAL MODIFICATION PROTEIN BINDING/PROTEIN TRANSPORT COMPLEX
Ref.: STRUCTURE OF THE RAB7:REP-1 COMPLEX: INSIGHTS INTO THE MECHANISM OF RAB PRENYLATION AND CHOROIDEREMIA DISEASE CELL(CAMBRIDGE,MASS.) V. 117 749 2004
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 199 families.
1 1VG0 Kd = 0.8 nM GER C20 H34 CC=C(/C)CC....
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 166 families.
1 1VG0 Kd = 0.8 nM GER C20 H34 CC=C(/C)CC....
2 1VG9 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
50% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 141 families.
1 1VG0 Kd = 0.8 nM GER C20 H34 CC=C(/C)CC....
2 1VG9 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GDP; Similar ligands found: 153
No: Ligand ECFP6 Tc MDL keys Tc
1 GDP 1 1
2 GTP 0.909091 1
3 GP3 0.881579 0.973684
4 GNH 0.858974 0.986667
5 GNP 0.839506 0.973684
6 G 0.828947 0.986486
7 5GP 0.828947 0.986486
8 G1R 0.82716 0.986667
9 GCP 0.82716 0.973684
10 GSP 0.817073 0.948718
11 GAV 0.797619 0.961039
12 GMV 0.792683 0.973684
13 G2P 0.77381 0.961039
14 G2R 0.770115 0.961039
15 GDP MG 0.759036 0.923077
16 GP2 0.756098 0.961039
17 GDP BEF 0.75 0.9
18 GDD 0.747253 0.961039
19 GKE 0.747253 0.961039
20 GDC 0.747253 0.961039
21 GPG 0.741573 0.961039
22 G3D 0.732558 0.986486
23 ALF 5GP 0.729412 0.888889
24 Y9Z 0.728261 0.902439
25 GTP MG 0.724138 0.923077
26 BEF GDP 0.724138 0.888889
27 G5P 0.723404 0.973684
28 GFB 0.72043 0.961039
29 GTG 0.72043 0.936709
30 GDR 0.72043 0.961039
31 G4P 0.715909 0.986486
32 GCP G 0.715909 0.935065
33 6CK 0.712766 0.936709
34 G3A 0.712766 0.973684
35 GDP ALF 0.7 0.888889
36 GDP AF3 0.7 0.888889
37 YGP 0.698925 0.901235
38 JB2 0.697917 0.961039
39 GKD 0.697917 0.961039
40 GDX 0.690722 0.973684
41 GPD 0.690722 0.925
42 GMP 0.684211 0.88
43 0O2 0.666667 0.986486
44 G G 0.659574 0.935065
45 JB3 0.656863 0.948718
46 NGD 0.650485 0.961039
47 GDP 7MG 0.636364 0.911392
48 DGI 0.636364 0.923077
49 U2G 0.634615 0.936709
50 GPX 0.634409 0.946667
51 IDP 0.632184 0.972973
52 2MD 0.632075 0.891566
53 CAG 0.62963 0.880952
54 CG2 0.622642 0.936709
55 FEG 0.619048 0.879518
56 MGD 0.614679 0.891566
57 ZGP 0.613208 0.869048
58 GH3 0.612903 0.973333
59 3GP 0.611765 0.946667
60 MD1 0.607143 0.891566
61 PGD 0.59292 0.925
62 DGT 0.591398 0.923077
63 BGO 0.588785 0.924051
64 TPG 0.582609 0.840909
65 DBG 0.582609 0.948718
66 2GP 0.574713 0.96
67 FE9 0.570175 0.776596
68 I2C FE2 CMO CMO 0.566372 0.808989
69 G A A A 0.553571 0.923077
70 MGP 0.553191 0.961039
71 U A G G 0.548673 0.935065
72 G4M 0.548387 0.880952
73 6G0 0.547368 0.961039
74 G1R G1R 0.542373 0.924051
75 P2G 0.527473 0.883117
76 PGD O 0.525 0.850575
77 ADP 0.522222 0.92
78 GGM 0.517544 0.901235
79 DG 0.516484 0.910256
80 DGP 0.516484 0.910256
81 P1G 0.516129 0.871795
82 G G U 0.509259 0.935065
83 G1G 0.508475 0.925
84 IMP 0.505495 0.959459
85 G C 0.504348 0.9
86 GPC 0.491525 0.879518
87 G7M 0.483871 0.948052
88 6AD 0.479592 0.841463
89 ATP 0.473684 0.92
90 G2Q 0.471154 0.961039
91 U G A 0.469697 0.888889
92 5FA 0.46875 0.92
93 AQP 0.46875 0.92
94 GTA 0.468468 0.936709
95 7DD 0.468085 0.906667
96 G G G RPC 0.466102 0.875
97 SGP 0.463158 0.82716
98 01G 0.462963 0.902439
99 B4P 0.457447 0.894737
100 AP5 0.457447 0.894737
101 A2D 0.456522 0.894737
102 G G G C 0.455285 0.9125
103 ACQ 0.454545 0.896104
104 5GP 5GP 0.454545 0.883117
105 ANP 0.454545 0.896104
106 A G C C 0.451613 0.911392
107 APC G U 0.45082 0.886076
108 G U34 0.449153 0.888889
109 DG DG 0.448598 0.865854
110 ITT 0.447917 0.868421
111 BA3 0.446809 0.894737
112 35G 0.444444 0.933333
113 C2E 0.444444 0.921053
114 PCG 0.444444 0.933333
115 MGO 0.441176 0.864198
116 AN2 0.4375 0.907895
117 G C C C 0.4375 0.924051
118 M33 0.43299 0.883117
119 UCG 0.429688 0.911392
120 A G U 0.42963 0.888889
121 ACP 0.428571 0.896104
122 MGQ 0.424528 0.935897
123 7DT 0.424242 0.906667
124 APR 0.424242 0.894737
125 AR6 0.424242 0.894737
126 93A 0.42268 0.833333
127 A4P 0.420168 0.869048
128 SAP 0.42 0.873418
129 AD9 0.42 0.896104
130 AGS 0.42 0.873418
131 G8D 0.42 0.875
132 CA0 0.418367 0.896104
133 ATF 0.417476 0.884615
134 AGO 0.414634 0.888889
135 NIA 0.413043 0.82716
136 MGV 0.412844 0.890244
137 TAT 0.411765 0.884615
138 A1R 0.411215 0.839506
139 ADQ 0.411215 0.871795
140 RGT 0.410714 0.909091
141 CGP 0.409836 0.86747
142 AMP 0.408602 0.893333
143 A 0.408602 0.893333
144 UP5 0.40678 0.873418
145 C2R 0.406593 0.906667
146 AMZ 0.406593 0.918919
147 JBT 0.405882 0.778947
148 A22 0.40566 0.907895
149 25L 0.405405 0.907895
150 ADX 0.40404 0.809524
151 8OD 0.401961 0.946667
152 4TC 0.4 0.851852
153 50T 0.4 0.883117
Ligand no: 2; Ligand: GER; Similar ligands found: 8
No: Ligand ECFP6 Tc MDL keys Tc
1 GER 1 1
2 FAR 1 1
3 650 0.785714 0.8125
4 SQL 0.709677 0.941176
5 FOH 0.628571 0.695652
6 64Z 0.514286 0.652174
7 CTV 0.447368 0.684211
8 28U 0.444444 0.615385
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1VG0; Ligand: GDP; Similar sites found: 416
This union binding pocket(no: 1) in the query (biounit: 1vg0.bio1) has 19 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 2VF7 ADP 0.0001442 0.48942 2
2 2ZPA ADP 0.0000964 0.46475 2.46154
3 2HF9 GSP 0.00000005203 0.61429 2.65487
4 1P72 ADP 0.00004612 0.40066 2.69461
5 3WYA GDP 0.0000000001248 0.78425 2.76498
6 2WHX ADP 0.00003684 0.54525 2.89855
7 5XDR ADP 0.00003905 0.51576 2.89855
8 5M7P ADP 0.000286 0.46957 2.89855
9 1NST A3P 0.004204 0.4056 3.07692
10 1QF5 RPL 0.01304 0.4536 3.24826
11 2J5V PCA 0.03272 0.41018 3.26975
12 3MD0 GDP 0.0000000001212 0.79911 3.38164
13 1SKQ GDP 0.000000001156 0.75127 3.38164
14 1FP6 ADP 0.00001073 0.52788 3.38164
15 2IS6 ADP 0.00008517 0.50656 3.38164
16 5G41 AP5 0.001453 0.47047 3.38164
17 2FAH GDP 0.0002334 0.46867 3.38164
18 5GJC ATP 0.000195 0.44726 3.39367
19 1T5C ADP 0.0000006145 0.64938 3.4384
20 2D2F ADP 0.00003884 0.54316 3.6
21 3IO3 ADP 0.00002497 0.49103 3.73563
22 3FWY ADP 0.000002598 0.54174 3.82166
23 2DPY ADP 0.00001397 0.56035 3.86473
24 1V8K ANP 0.00001473 0.54284 3.86473
25 2GDJ ANP 0.0002343 0.48564 3.86473
26 2GK6 ADP 0.0006539 0.47652 3.86473
27 4PX9 ADP 0.00002046 0.47519 3.86473
28 2D7D ADP 0.0004093 0.47411 3.86473
29 1Z6T ADP 0.0001681 0.46447 3.86473
30 2JLR ANP 0.0007067 0.44736 3.86473
31 3FYH ADP 0.0004345 0.40774 3.86473
32 3VX3 ADP 0.00001205 0.503 4.03226
33 1H65 GDP 0.0000005536 0.53343 4.07407
34 5K5Z ANP 0.0001192 0.49538 4.14013
35 1GOJ ADP 0.00000008965 0.694 4.22535
36 3FKQ ATP 0.00001923 0.50542 4.28954
37 3EC1 GDP 0.0000000003906 0.74787 4.33604
38 3BFV ADP 0.000009367 0.55219 4.34783
39 1G3Q ADP 0.0000107 0.54186 4.34783
40 4R43 GDP 0.00005107 0.51714 4.34783
41 3EZ2 ADP 0.00007451 0.51635 4.34783
42 1XKV ATP 0.00002933 0.51486 4.34783
43 1ION ADP 0.00003426 0.5118 4.34783
44 4D81 ADP 0.00007407 0.49074 4.34783
45 1YTM ATP 0.0001874 0.44666 4.34783
46 4A4Z ANP 0.00276 0.43463 4.34783
47 4PJ3 ANP 0.004389 0.41221 4.34783
48 3DKP ADP 0.0001488 0.49503 4.4898
49 2XT3 ADP 0.0000002062 0.6693 4.65116
50 4QM7 GTP 0.00002178 0.53476 4.67836
51 2HCJ GDP 0.00000000002374 0.83369 4.83092
52 3U6B GDP 0.00000000003274 0.82687 4.83092
53 1D8T GDP 0.00000000006749 0.79696 4.83092
54 4G5G GDP 0.00000000009356 0.79021 4.83092
55 3U6K GDP 0.0000000001571 0.77949 4.83092
56 5JBQ GDP 0.00000000009975 0.69871 4.83092
57 2BVN GNP 0.000000002066 0.69238 4.83092
58 1D2E GDP 0.000000004565 0.67714 4.83092
59 4PC3 GDP 0.000000005142 0.67485 4.83092
60 5L3V GDP 0.0000004459 0.59725 4.83092
61 4V03 ADP 0.000004046 0.53655 4.83092
62 2C04 GCP 0.00001357 0.51294 4.83092
63 2Q2Y MKR 0.0008975 0.5024 4.83092
64 5TSH ANP 0.00001361 0.49293 4.83092
65 5I0H ADP BEF 0.0001371 0.48622 4.83092
66 5TSH ADP 0.000003991 0.47919 4.83092
67 2FSH ANP 0.0007083 0.46857 4.83092
68 1P9B GDP 0.0001582 0.46684 4.83092
69 5J1J ANP 0.00002366 0.46364 4.83092
70 1NY5 ADP 0.0002668 0.45686 4.83092
71 2O0J ADP 0.007845 0.42229 4.83092
72 4P32 ADP 0.0004256 0.42072 4.83092
73 1OYY AGS 0.006546 0.41674 4.83092
74 1J99 AND 0.02131 0.40226 4.83092
75 2I4I AMP 0.005982 0.40089 4.83092
76 5M04 GDP 0.0000000001164 0.68164 5
77 2NCD ADP 0.000001143 0.62285 5
78 1NJF ADP 0.0000168 0.4958 5.2
79 1NJF AGS 0.00003122 0.46678 5.2
80 2IYL GDP 0.000000168 0.63531 5.28169
81 2CHG ANP 0.0001064 0.4737 5.30973
82 1KK1 GNP 0.0000000008273 0.75836 5.31401
83 5KSZ GCP 0.0000002728 0.60693 5.31401
84 1YQT ADP 0.000003827 0.59735 5.31401
85 4LYA ATP 0.00001135 0.54068 5.31401
86 1XMV ADP 0.00008767 0.49945 5.31401
87 1W5T ADP 0.001015 0.43173 5.31401
88 1W5T ANP 0.0006033 0.42591 5.31401
89 4E03 ADP 0.00002263 0.52676 5.33981
90 2BEK ATP 0.0003073 0.43059 5.53846
91 4P4T GDP 0.0000001619 0.58018 5.55556
92 2ZTS ADP 0.0001699 0.45418 5.57769
93 4IDN GNP 0.0005023 0.42064 5.68928
94 3IUY AMP 0.002369 0.43779 5.70175
95 2RCN GDP 0.000000000001424 0.87672 5.7971
96 4LC1 GDP 0.0000000007023 0.74854 5.7971
97 1TQ4 GDP 0.0000000009352 0.65044 5.7971
98 3VMF GTP 0.00000001281 0.55766 5.7971
99 3WXM GTP 0.00000002051 0.55259 5.7971
100 2XTZ GSP 0.00000002587 0.55097 5.7971
101 1G41 ADP 0.00002618 0.5171 5.7971
102 3TBK ANP 0.0001352 0.51087 5.7971
103 1IHU AF3 0.000005146 0.49536 5.7971
104 1CR1 TTP 0.0001348 0.48654 5.7971
105 1IHU ADP 0.000005831 0.48377 5.7971
106 3FVQ ATP 0.000266 0.43859 5.7971
107 3ZQ6 ADP ALF 0.00003858 0.43426 5.7971
108 3VM7 GLC 0.01232 0.41613 5.7971
109 3QDK QDK 0.0313 0.4002 5.7971
110 2IL4 COA 0.00496 0.40985 5.82524
111 1RRC ADP 0.000002892 0.61101 6.28019
112 2OBM ADP 0.00009814 0.52742 6.28019
113 4HSE ADP 0.00003755 0.51655 6.28019
114 1R6B ADP 0.00003834 0.51612 6.28019
115 1AZT GSP 0.00000006917 0.51169 6.28019
116 2CE7 ADP 0.00006777 0.49837 6.28019
117 2FNA ADP 0.0000488 0.45757 6.28019
118 5UAV NDP 0.02362 0.40229 6.28019
119 5UAV TFB 0.02482 0.40229 6.28019
120 4AG5 ADP 0.000002282 0.60894 6.37755
121 1BG2 ADP 0.0000004601 0.65402 6.46154
122 4OHY ANP 0.0002513 0.41737 6.49652
123 3UIE ANP 0.00001638 0.52632 6.5
124 3NHB ADP 0.000001846 0.61291 6.76329
125 3ZFD ANP 0.00003834 0.50958 6.76329
126 1TAD ALF 0.00000007722 0.50944 6.76329
127 1TAD GDP 0.00000007722 0.50944 6.76329
128 2C9O ADP 0.00006045 0.46521 6.76329
129 5MZN ADP 0.00112 0.46478 6.76329
130 5WRJ A3P 0.002577 0.43416 6.76329
131 5WRI A3P 0.002608 0.43037 6.76329
132 1XX6 ADP 0.001622 0.44564 6.80628
133 4TTQ ATP 0.0001396 0.49635 6.97674
134 2IXE ATP 0.0004282 0.42235 7.01107
135 1OS1 ATP 0.0001374 0.40486 7.03704
136 1B7T ADP 0.000149 0.48287 7.05128
137 4RZ3 ADP 0.0000128 0.52736 7.11864
138 1KK8 BEF ADP 0.0001139 0.47154 7.19424
139 4DCT GDP 0.00000000005401 0.78777 7.24638
140 2OG2 MLI 0.000003708 0.59991 7.24638
141 3B9Q MLI 0.00001084 0.57641 7.24638
142 4IHQ ADP 0.0001304 0.50447 7.24638
143 4JLV ADP 0.0001598 0.50016 7.24638
144 2XAU ADP 0.00006707 0.49858 7.24638
145 5LTJ ADP 0.00001996 0.49715 7.24638
146 2X0K PPV 0.02034 0.41644 7.39645
147 4PPF FLC 0.000001114 0.643 7.42857
148 3EWA ANP 0.0000549 0.51564 7.45342
149 1SQ5 ADP 0.00003209 0.51971 7.46753
150 4LJ9 ACP 0.000261 0.48341 7.66962
151 4FCW ADP 0.0001443 0.4894 7.71704
152 3P4X ADP 0.000006123 0.56936 7.72947
153 1WDT GTP 0.000001643 0.53905 7.72947
154 2QEN ADP 0.00004611 0.48881 7.72947
155 1IN4 ADP 0.0000342 0.48329 7.72947
156 3DZD ADP 0.0003447 0.46117 7.72947
157 4YS0 ADP 0.0007178 0.43882 7.72947
158 5KSP GDP 0.0000000566 0.64755 7.89474
159 4WZ6 ATP 0.00001381 0.56689 7.93103
160 1CS4 GSP 0.0000001079 0.51476 8
161 3T34 GDP 0.000008401 0.48447 8.05556
162 4R2I ANP 0.0005089 0.48199 8.09524
163 1FQJ GDP 0.00000008106 0.55674 8.16327
164 1FQK GDP 0.0000001767 0.5467 8.16327
165 3PQC GDP 0.00000001113 0.66988 8.20513
166 1PUJ GNP 0.00000001164 0.65915 8.21256
167 1JWY GDP 0.0000003759 0.59233 8.21256
168 3DEF GDP 0.0000004221 0.5901 8.21256
169 5L3S GNP 0.000001725 0.57974 8.21256
170 5L3W GDP 0.000001044 0.56253 8.21256
171 1JWY ADP 0.00007996 0.50131 8.21256
172 3B7G ANP 0.000205 0.48233 8.21256
173 5IFS ADP 0.00009709 0.47731 8.21256
174 4QOS ADP 0.0002111 0.47601 8.21256
175 1FNN ADP 0.00008246 0.4679 8.21256
176 3QXC ATP 0.0004359 0.40632 8.21256
177 4IOK XPO 0.000885 0.40259 8.21256
178 1OFH ADP 0.00008924 0.49296 8.3871
179 2W58 ADP 0.0000003846 0.66703 8.41584
180 2Y65 ADP 0.000001236 0.62691 8.69565
181 1SVI GDP 0.00000000003933 0.82298 8.71795
182 4ZNL BEF ADP 0.0003162 0.44751 8.75912
183 3IIJ ADP 0.000004076 0.5694 8.88889
184 2PL3 ADP 0.000168 0.49911 8.8983
185 5E5U MLI 0.01464 0.40086 9.04523
186 1G6O ADP 0.00008732 0.49339 9.09091
187 1VHT BA3 0.0006241 0.45467 9.17431
188 3CNL GNP 0.0000000007955 0.75919 9.17874
189 3LRE ADP 0.0000001388 0.68558 9.17874
190 1JJV ATP 0.00004395 0.53894 9.2233
191 5L3R GCP 0.000001721 0.49648 9.30233
192 1U0J ADP 0.0001812 0.4975 9.3633
193 5VGR GDP 0.0003038 0.45384 9.51276
194 2VVG ADP 0.00000008619 0.69364 9.66184
195 4H1V GNP 0.0000004774 0.57415 9.66184
196 4ZG4 VO4 ADP 0.0001449 0.48947 9.66184
197 4IEE AGS 0.0003748 0.48208 9.66184
198 5FTB ANP 0.0002659 0.47147 9.66184
199 5FHD ADP ALF 0.0002154 0.44171 9.66184
200 3RC3 ANP 0.002674 0.44038 9.66184
201 4QRH 0O2 0.003926 0.42045 9.66184
202 4I9B 1KA 0.04751 0.40147 9.66184
203 5J1S ATP 0.0006783 0.40639 9.7561
204 4LPS GDP 0.00000004352 0.65285 9.91736
205 4CVN ADP 0.000003356 0.59143 9.94764
206 2PZE ATP 0.000002109 0.61638 10.0437
207 3ZIA ATP 0.00003316 0.51905 10.0719
208 3ZIA ADP 0.00005813 0.4954 10.0719
209 1F9V ADP 0.0000006935 0.63434 10.0865
210 1BO4 COA 0.004335 0.42528 10.119
211 1M7G AV2 0.000003421 0.58171 10.1449
212 5IRR GSP 0.000001139 0.52343 10.1449
213 1W0J ADP 0.00002781 0.50957 10.1449
214 5LB3 ADP 0.0001029 0.50951 10.1449
215 1W0J ADP BEF 0.0004128 0.46242 10.1449
216 1M7G ADP 0.0001452 0.4017 10.1449
217 4XVU ATP 0.00003754 0.51623 10.1695
218 2WOJ ADP ALF 0.00004344 0.43505 10.1695
219 3Q9L ATP 0.0001672 0.46507 10.3846
220 4P3Y GDP 0.00000000003464 0.82567 10.4396
221 3KTA AP5 0.0003216 0.46251 10.4396
222 2AWN ADP 0.00000001651 0.75475 10.628
223 2QZ4 ADP 0.00004184 0.50787 10.628
224 4XGU ADP 0.0001427 0.46897 10.628
225 3RLF ANP 0.0002159 0.42605 10.628
226 5MEX SZZ 0.01306 0.41684 10.628
227 1G7C 5GP 0.00000004265 0.66366 10.6383
228 2X7I CIT 0.005174 0.42162 10.7143
229 1YRB GDP 0.00000000009093 0.75244 11.1111
230 5CK5 GDP 0.0000000001685 0.67693 11.1111
231 1XP8 AGS 0.000104 0.50928 11.1111
232 4BQS ADP 0.00002142 0.53509 11.3636
233 4BQS K2Q 0.0003658 0.48903 11.3636
234 2OFW ADX 0.0002622 0.49992 11.5385
235 4YDS ATP 0.0000128 0.56225 11.5942
236 2VB6 ADP BEF 0.0001955 0.48354 11.5942
237 2KIN ADP 0.0000002798 0.48336 11.5942
238 4PFO ADP 0.0002658 0.48131 11.5942
239 3BER AMP 0.001984 0.44147 11.5942
240 1K6M AGS 0.0002895 0.42047 11.5942
241 1Y63 ADP 0.000004675 0.56656 11.9565
242 5HCN GCP 0.0000000001586 0.76605 12.0773
243 2ZR9 DTP 0.00004233 0.52101 12.0773
244 1R0X ATP 0.0002804 0.48824 12.5604
245 4B1M FRU FRU 0.0139 0.41155 12.973
246 1DAR GDP 0.000000002274 0.72426 13.0435
247 2C77 GNP 0.00000001186 0.60932 13.0435
248 2C78 GNP 0.000000006046 0.60616 13.0435
249 1LVG ADP 0.0000005852 0.62949 13.1313
250 3H4S ADP 0.0000003113 0.6595 13.4715
251 4FRZ ADP 0.000000815 0.63079 13.4715
252 3QKT ANP 0.0002473 0.41772 13.5266
253 5N69 ADP 0.0001926 0.47237 13.5678
254 3QF7 ANP 0.0002382 0.44889 14
255 2QN6 GDP 0.00000000006166 0.81344 14.0097
256 4RD0 GDP 0.000000001977 0.7081 14.0097
257 4KBF AMP 0.001215 0.45712 14.0097
258 3E70 GDP 0.0000003927 0.60849 14.4928
259 5HR5 ADP 0.0002156 0.4727 14.4928
260 2OZE AGS 0.0001205 0.46142 14.4928
261 2CBZ ATP 0.000000813 0.64524 14.9758
262 3AB3 GDP 0.00000005344 0.64003 14.9758
263 3DC4 ADP 0.000002658 0.59651 14.9758
264 1ZCB GDP 0.0000001589 0.52859 14.9758
265 3CX8 GSP 0.00000008446 0.50908 14.9758
266 4GOX A3P 0.0004863 0.41631 14.9758
267 4WOP CTP 0.0004698 0.43137 15.1111
268 3A4M ADP 0.000002653 0.59655 15.3846
269 4J0Q GDP 0.00000000007735 0.80863 15.4589
270 4OI4 ATP 0.0006192 0.41242 15.6522
271 4KFU ACP 0.00001001 0.57427 16.0377
272 4XTR ADP 0.00002336 0.51836 16.2162
273 4XTR ATP 0.0000337 0.51836 16.2162
274 1W7J ADP BEF 0.0001214 0.47026 16.5563
275 3BOS CDP 0.0002041 0.48849 16.9421
276 4B47 GDP 0.000000000006644 0.8607 17.3913
277 4HI0 GDP 0.00000009302 0.57614 17.8744
278 5H67 ATP 0.002397 0.4099 18.0851
279 5H56 ADP 0.0001591 0.49867 18.4615
280 5H56 TYD 0.0001591 0.49867 18.4615
281 2FH5 GTP 0.0000000001523 0.6808 19.3237
282 1GXU 2HP 0.00008647 0.50848 19.7802
283 3KJI ADP 0.000004983 0.54263 20.0787
284 2X77 GDP 0.0000000001074 0.7739 20.1058
285 3TK1 GDP 0.00000000001848 0.85533 20.2899
286 1MKY GDP 0.00000000001134 0.83382 20.2899
287 3DOE GTP 0.000000003273 0.60089 20.8333
288 2XTN GTP 0.0000003871 0.52856 21.256
289 1KSH GDP 0.000000000579 0.65748 21.5054
290 1HTW ADP 0.0000232 0.52625 21.519
291 5I34 GDP 0.0000315 0.49087 22.2222
292 2ODE ALF GDP 0.00000008446 0.64997 23.1429
293 4ZKD GDP 0.000000008004 0.69246 23.1884
294 5GOE GDP 0.000000005155 0.68504 23.6715
295 3ZS9 ADP ALF 0.00004034 0.43609 23.6842
296 5BQ5 ADP BEF 0.00002408 0.51874 23.8095
297 1SVK ALF GDP 0.00000008312 0.50131 24.6459
298 3WY9 GDP 0.00000000003046 0.8284 25
299 2OM2 GDP 0.000000232 0.56309 25.2308
300 5KUT GDP 0.0000000007956 0.67861 25.9259
301 1BH2 GSP 0.0000002129 0.4976 26.0317
302 5IRN ADP 0.00002713 0.51005 26.087
303 5KDO GDP 0.0000003049 0.55921 27.027
304 1GWN GTP 0.000000007257 0.61903 27.3171
305 1Y3A GDP 0.000000161 0.54755 27.9635
306 4GOJ GNP 0.000000001701 0.62447 28.0423
307 4ZI2 GNP 0.000000001739 0.62408 28.4211
308 5DI3 GNP 0.00000000161 0.62694 28.5024
309 4M9Q GNP 0.000000002048 0.62238 28.5024
310 1GOT GDP 0.000000215 0.55416 28.7671
311 3AQ4 GDP 0.0000000007662 0.73429 29.3478
312 1FZQ GDP 0.00000000009135 0.7907 29.8343
313 4KAX GTP 0.000000005898 0.60637 30.1775
314 5MVR ADP 0.00003582 0.47847 30.2469
315 2A5F GTP 0.00000001922 0.56393 30.2857
316 1M7B GTP 0.000000002877 0.63325 30.4348
317 2WKQ GTP 0.000000001169 0.61752 30.9179
318 3PCR GTP 0.000000008285 0.58757 31.4815
319 2W83 GTP 0.000000008473 0.58788 31.5152
320 4YLG GDP 0.000000000908 0.71228 31.7919
321 1KO8 6PG 0.0001645 0.45548 32
322 3N5C GDP 0.0000000004426 0.75808 32.716
323 1RYH GNP 0.0000000002087 0.74815 33.0049
324 1G7S GDP 0.0000000005048 0.74271 33.3333
325 1E96 GTP 0.000000001013 0.59464 33.3333
326 2QTV GNP 0.00000003881 0.55572 33.5329
327 2J59 GTP 0.00000000913 0.58642 33.7349
328 5FG3 GDP 0.00000000000942 0.71792 33.8164
329 4NCN GTP 0.000000002065 0.60569 33.8164
330 4TMZ GSP 0.000000002623 0.60205 33.8164
331 1I4D GDP 0.000000000008675 0.85505 33.8542
332 1NF3 GNP 0.000000004403 0.57421 34.359
333 1MH1 GNP 0.0000000008895 0.58203 34.4086
334 3SBD GNP 0.0000000004248 0.6083 34.7594
335 1G4U GDP 0.000000002386 0.65231 34.7826
336 1GP2 GDP 0.0000001935 0.54425 35.2113
337 4DID GDP 0.0000000001171 0.77217 35.2332
338 2ZEJ GDP 0.00000001019 0.548 35.3261
339 2NGR GDP 0.000000000101 0.77514 35.6021
340 1GRN GDP 0.0000000003738 0.70365 35.6021
341 1A4R GNH 0.0000000009089 0.68786 35.6021
342 1A4R GDP 0.0000000008393 0.67028 35.6021
343 4ITR GDP 0.000000001998 0.65486 35.6021
344 2WMO GTP 0.000000001884 0.70485 35.7895
345 2FJU GSP 0.0000000008548 0.65239 35.9551
346 1UPT GTP 0.000000003657 0.61195 36.2573
347 1HE1 GDP 0.0000000008308 0.6524 36.3636
348 1HE1 AF3 0.01766 0.40839 36.3636
349 3REF GDP 0.000000006749 0.60314 36.5979
350 4V0K GDP 0.000000008937 0.57185 37.2781
351 5EE5 GTP 0.0000000006891 0.72886 37.4269
352 4YC7 GNP 0.0000000005422 0.73359 37.5691
353 4BAS GNP 0.0000001817 0.55118 37.6884
354 3T1O GDP 0.0000000466 0.6417 37.8788
355 3T12 GDP ALF 0.0000000884 0.56287 37.8788
356 2V7Q ATP 0.0000173 0.52525 38
357 2V7Q ADP 0.0001128 0.50075 38
358 2CK3 ANP 0.0004604 0.43859 38
359 2CK3 ADP 0.0004304 0.41726 38
360 1WF3 GNP 0.00000001144 0.5451 38.1642
361 2GJ8 ALF GDP 0.000000006479 0.55436 38.3721
362 1MR3 G3D 0.0000000003268 0.75147 40.3315
363 5JCP GDP ALF 0.0000000084 0.6471 41.0628
364 2GCO GNP 0.000000001602 0.67758 42.2886
365 2GCN GDP 0.0000000009128 0.63675 42.2886
366 1DS6 GDP 0.00000000001135 0.83382 42.7083
367 2CJW GDP 0.0000000000006009 0.89456 43.2292
368 2W2X GSP 0.000000001575 0.64354 43.7838
369 3M1I GTP 0.00000000006337 0.62303 43.9614
370 3WYF GTP 0.00000000007379 0.60814 43.9614
371 1OW3 GDP 0.000000001342 0.70471 44.0415
372 3T5G GDP 0.000000000005432 0.78743 45.3039
373 1KMQ GNP 0.00000000491 0.59634 45.6522
374 3Q72 GNP 0.000000000002553 0.88099 45.7831
375 3GJ4 GDP 0.000000000002294 0.86686 45.8937
376 3GJ7 GDP 0.000000000002487 0.8652 45.8937
377 3GJ8 GDP 0.00000000000546 0.83397 45.8937
378 3GJ5 GDP 0.000000000006524 0.83038 45.8937
379 2J0V GDP 0.00000000003152 0.79863 45.8937
380 3GJX GTP 0.0000000001207 0.77679 45.8937
381 5HPY GDP 0.00000000173 0.69981 45.9459
382 1XTQ GDP 0.00000000004088 0.66961 46.3277
383 3GJ3 GDP 0.000000000002716 0.86337 46.3768
384 3GJ0 GDP 0.0000000000112 0.83409 46.3768
385 3CH5 GDP 0.000000000008554 0.82492 46.3768
386 5UWP GNP 0.00000000003672 0.8039 46.3768
387 5UWU GNP 0.00000000003617 0.80102 46.3768
388 5UWI GNP 0.00000000003973 0.79913 46.3768
389 5UWR GNP 0.00000000004237 0.79784 46.3768
390 5UWT GNP 0.00000000005135 0.79397 46.3768
391 5BXQ GDP 0.000000000003831 0.77546 46.3768
392 5UWQ GNP 0.00000000003238 0.63098 46.3768
393 5DIF GNP 0.00000000003389 0.63032 46.3768
394 5UWJ GNP 0.00000000003679 0.62953 46.3768
395 5UWW GNP 0.00000000003646 0.62946 46.3768
396 5DHF GNP 0.00000000004667 0.62665 46.3768
397 5UWH GNP 0.00000000004945 0.6262 46.3768
398 1IBR GNP 0.00000000005141 0.62522 46.3768
399 4HAT GNP 0.00000000004117 0.61511 46.3768
400 5UWS GNP 0.00000000005266 0.61246 46.3768
401 5DI9 GNP 0.00000000006207 0.61064 46.3768
402 4D0N GDP 0.00000000004637 0.80472 46.4865
403 3LXR GDP 0.0000000002232 0.74683 46.4865
404 2HT6 GDP 0.0000000000008507 0.90431 46.5517
405 4XOI GTP 0.000000001588 0.71894 46.6667
406 4XSH GSP 0.0000000009688 0.66793 46.9274
407 1CXZ GSP 0.000000004003 0.61414 47.2527
408 5IRC GDP 0.00000002814 0.62957 47.3118
409 1TX4 ALF GDP 0.000000005109 0.59646 47.4576
410 4U5X GNP 0.000000002677 0.65025 47.7528
411 3Q85 GNP 0.0000000000007665 0.88952 48.5207
412 2G77 GDP 0.00000000003363 0.74761 48.9899
413 2G77 AF3 0.009673 0.42191 48.9899
414 5UQW GDP 0.000000000006197 0.82939 49.2063
415 3E5H GNP 0.00000000007663 0.63234 49.4382
416 5SZH GNP 0.0000000000007634 0.87859 49.7537
417 5UWO GNP 0.00000000003212 0.63108 50
418 3WYG GTP 0.0000000001352 0.6018 50
Pocket No.: 2; Query (leader) PDB : 1VG0; Ligand: GER; Similar sites found: 22
This union binding pocket(no: 2) in the query (biounit: 1vg0.bio1) has 17 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 4WG0 CHD 0.003807 0.44038 None
2 1YOK P6L 0.03276 0.40282 2.73438
3 1TO9 HMH 0.01899 0.40047 3.46154
4 3IB1 IMN 0.01281 0.40725 3.76812
5 4IN9 SER TRP PHE PRO 0.01606 0.40231 4.21687
6 3HP9 CF1 0.008457 0.42134 4.34783
7 1U25 IHS 0.03133 0.40508 4.45104
8 2ED4 NAD 0.01857 0.40206 4.69799
9 3KA2 2NC 0.04292 0.40778 4.92611
10 1RZ1 NAD 0.01082 0.41487 6.21118
11 5DQY BEZ 0.00698 0.42633 6.66667
12 5JBE MAL 0.001682 0.43963 6.76329
13 1ZPD CIT 0.01549 0.41013 7.24638
14 5CXI 5TW 0.005854 0.41468 8.37438
15 2XRH NIO 0.01629 0.40684 9
16 4KCF FMN 0.007891 0.40422 9.17874
17 4C2W ANP 0.01584 0.40519 11.5385
18 1Y63 ADP 0.007674 0.40901 11.9565
19 1SBR VIB 0.004779 0.42856 13
20 5KVM THR TYR PHE ALA VAL LEU MET VAL SER 0.03062 0.40003 13.6842
21 5CSD ACD 0.0379 0.40246 17.6101
22 1LTI GAL 0.01938 0.40483 24.2718
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