Receptor
PDB id Resolution Class Description Source Keywords
1W5T 2.4 Å NON-ENZYME: TRANSCRIPT_TRANSLATE STRUCTURE OF THE AEROPYRUM PERNIX ORC2 PROTEIN (ADPNP-ADP COMPLEXES) AEROPYRUM PERNIX ORC CDC6 DNA REPLICATION INITIATION DNA BINDING PROTEIN AAA+ ATPASE
Ref.: CONFORMATIONAL CHANGES INDUCED BY NUCLEOTIDE BINDING IN CDC6/ORC FROM AEROPYRUM PERNIX J.MOL.BIOL. V. 343 547 2004
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ADP C:700;
Valid;
none;
submit data
427.201 C10 H15 N5 O10 P2 c1nc(...
ANP A:700;
B:700;
Valid;
Valid;
none;
none;
submit data
506.196 C10 H17 N6 O12 P3 c1nc(...
MG A:701;
B:701;
C:701;
Part of Protein;
Part of Protein;
Part of Protein;
none;
none;
none;
submit data
24.305 Mg [Mg+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1W5T 2.4 Å NON-ENZYME: TRANSCRIPT_TRANSLATE STRUCTURE OF THE AEROPYRUM PERNIX ORC2 PROTEIN (ADPNP-ADP COMPLEXES) AEROPYRUM PERNIX ORC CDC6 DNA REPLICATION INITIATION DNA BINDING PROTEIN AAA+ ATPASE
Ref.: CONFORMATIONAL CHANGES INDUCED BY NUCLEOTIDE BINDING IN CDC6/ORC FROM AEROPYRUM PERNIX J.MOL.BIOL. V. 343 547 2004
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 257 families.
1 1W5S - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
2 1W5T - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 222 families.
1 1W5S - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
2 1W5T - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
50% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 185 families.
1 1W5S - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
2 1W5T - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ADP; Similar ligands found: 435
No: Ligand ECFP6 Tc MDL keys Tc
1 ADP 1 1
2 ATP 0.9 1
3 A2D 0.895522 0.971831
4 AQP 0.887324 1
5 5FA 0.887324 1
6 AP5 0.884058 0.971831
7 B4P 0.884058 0.971831
8 BA3 0.869565 0.971831
9 AN2 0.84507 0.985915
10 M33 0.833333 0.958333
11 ACQ 0.826667 0.972222
12 A 0.823529 0.971429
13 AMP 0.823529 0.971429
14 ACP 0.821918 0.972222
15 AR6 0.810811 0.971831
16 APR 0.810811 0.971831
17 ANP 0.802632 0.972222
18 AD9 0.8 0.972222
19 AGS 0.8 0.945946
20 SAP 0.8 0.945946
21 ADX 0.783784 0.873418
22 CA0 0.783784 0.945205
23 TAT 0.779221 0.958904
24 AMP MG 0.774648 0.891892
25 50T 0.773333 0.958333
26 ABM 0.763889 0.917808
27 APC 0.763158 0.958904
28 PRX 0.763158 0.893333
29 ATF 0.759494 0.958904
30 A22 0.753086 0.985915
31 A12 0.743243 0.958904
32 AP2 0.743243 0.958904
33 ADP MG 0.736842 0.905405
34 SRA 0.736111 0.918919
35 ADQ 0.73494 0.945205
36 25L 0.732558 0.985915
37 ADP BEF 0.727273 0.881579
38 BEF ADP 0.727273 0.881579
39 5AL 0.725 0.931507
40 2A5 0.717949 0.918919
41 A1R 0.714286 0.907895
42 AU1 0.714286 0.972222
43 ADP PO3 0.708861 0.943662
44 PAP 0.708861 0.985714
45 ATR 0.708861 0.971429
46 SRP 0.707317 0.906667
47 7D3 0.706667 0.905405
48 25A 0.702381 0.971831
49 ATP MG 0.7 0.905405
50 OAD 0.697674 0.945205
51 RBY 0.6875 0.932432
52 ADV 0.6875 0.932432
53 00A 0.686047 0.883117
54 5SV 0.682353 0.848101
55 8QN 0.682353 0.931507
56 OOB 0.682353 0.931507
57 3OD 0.681818 0.945205
58 BIS 0.681818 0.933333
59 ADP ALF 0.674699 0.87013
60 ALF ADP 0.674699 0.87013
61 AMO 0.674419 0.932432
62 4AD 0.674419 0.92
63 PAJ 0.674419 0.884615
64 GAP 0.670732 0.893333
65 MAP 0.670588 0.945946
66 DLL 0.666667 0.931507
67 ANP MG 0.666667 0.894737
68 VO4 ADP 0.666667 0.931507
69 AHX 0.666667 0.896104
70 ADP VO4 0.666667 0.931507
71 PTJ 0.662921 0.896104
72 3UK 0.659091 0.918919
73 SON 0.658228 0.932432
74 LAD 0.651685 0.860759
75 WAQ 0.651685 0.883117
76 PR8 0.651685 0.85
77 ITT 0.65 0.943662
78 7D4 0.65 0.905405
79 G5P 0.648936 0.921053
80 RAB 0.647059 0.84507
81 ADN 0.647059 0.84507
82 XYA 0.647059 0.84507
83 TXA 0.644444 0.932432
84 1ZZ 0.644444 0.839506
85 ME8 0.644444 0.839506
86 NB8 0.644444 0.896104
87 FYA 0.644444 0.905405
88 6AD 0.642857 0.909091
89 ADP BMA 0.640449 0.918919
90 G3A 0.638298 0.921053
91 DAL AMP 0.632184 0.905405
92 AFH 0.631579 0.884615
93 9SN 0.630435 0.871795
94 GTA 0.625 0.886076
95 YAP 0.623656 0.894737
96 FA5 0.623656 0.906667
97 UP5 0.622449 0.92
98 XAH 0.617021 0.839506
99 AV2 0.616279 0.917808
100 AOC 0.615385 0.821918
101 48N 0.612245 0.896104
102 4UV 0.610526 0.894737
103 TXD 0.606061 0.907895
104 DND 0.606061 0.932432
105 NAX 0.606061 0.873418
106 NXX 0.606061 0.932432
107 NAI 0.606061 0.907895
108 6V0 0.606061 0.896104
109 5N5 0.605634 0.819444
110 5AS 0.604938 0.77907
111 A4P 0.60396 0.843373
112 DAT 0.60241 0.905405
113 A2R 0.602273 0.985915
114 TXE 0.6 0.907895
115 OMR 0.6 0.851852
116 4UU 0.597938 0.894737
117 A A 0.597826 0.944444
118 A4D 0.597222 0.819444
119 5CD 0.597222 0.805556
120 AP0 0.594059 0.896104
121 4TC 0.594059 0.896104
122 A3P 0.592593 0.971429
123 139 0.592233 0.873418
124 T5A 0.592233 0.841463
125 7D5 0.592105 0.878378
126 ATP A A A 0.589474 0.930556
127 LAQ 0.585859 0.839506
128 MYR AMP 0.585106 0.817073
129 YLP 0.58 0.819277
130 UPA 0.578431 0.907895
131 7DD 0.578313 0.985714
132 ADJ 0.576923 0.851852
133 3AM 0.576923 0.929577
134 COD 0.575472 0.811765
135 NAD 0.575472 0.931507
136 3AT 0.574713 0.971831
137 JB6 0.574468 0.883117
138 4UW 0.574257 0.860759
139 EP4 0.573333 0.753247
140 A2P 0.573171 0.957143
141 CNA 0.571429 0.932432
142 TYM 0.568627 0.906667
143 PPS 0.568182 0.873418
144 TYR AMP 0.56701 0.881579
145 DTA 0.565789 0.786667
146 M2T 0.565789 0.734177
147 AR6 AR6 0.565657 0.917808
148 A3D 0.564815 0.918919
149 3DH 0.564103 0.773333
150 G5A 0.563218 0.77907
151 YLB 0.563107 0.819277
152 YLC 0.563107 0.839506
153 AMP DBH 0.561224 0.893333
154 MTA 0.558442 0.773333
155 DTP 0.556818 0.905405
156 AHZ 0.554455 0.817073
157 NA7 0.553191 0.958904
158 IOT 0.552381 0.831325
159 7MD 0.55 0.8625
160 ZAS 0.55 0.766234
161 IMO 0.548781 0.929577
162 YLA 0.54717 0.819277
163 NAE 0.544643 0.894737
164 TAD 0.544554 0.884615
165 A5A 0.544444 0.807229
166 2AM 0.544304 0.943662
167 TSB 0.543478 0.819277
168 6RE 0.54321 0.759494
169 AYB 0.542056 0.809524
170 NAQ 0.539823 0.871795
171 V3L 0.539326 0.971831
172 ARG AMP 0.539216 0.829268
173 AF3 ADP 3PG 0.538462 0.8375
174 SSA 0.538462 0.8
175 LA8 ALF 3PG 0.538462 0.8375
176 ALF ADP 3PG 0.538462 0.8375
177 ZID 0.535088 0.918919
178 LPA AMP 0.533981 0.817073
179 54H 0.532609 0.788235
180 52H 0.532609 0.77907
181 VMS 0.532609 0.788235
182 BTX 0.53211 0.841463
183 J7C 0.53012 0.769231
184 A3N 0.53012 0.786667
185 5X8 0.528736 0.763158
186 BT5 0.527273 0.831325
187 5CA 0.526882 0.8
188 53H 0.526882 0.77907
189 ARU 0.526316 0.860759
190 EAD 0.525862 0.873418
191 RGT 0.525253 0.958904
192 OVE 0.52439 0.905405
193 S4M 0.52381 0.666667
194 7DT 0.522727 0.985714
195 GDP 0.522222 0.92
196 DDS 0.522222 0.878378
197 AVV 0.521277 0.896104
198 NDE 0.521008 0.932432
199 7MC 0.518868 0.841463
200 DSH 0.518072 0.725
201 MAO 0.517647 0.759036
202 LSS 0.515789 0.761364
203 DSZ 0.515789 0.8
204 NSS 0.515789 0.8
205 P5A 0.515464 0.744444
206 DZD 0.513514 0.884615
207 NVA LMS 0.510417 0.761364
208 12D 0.509615 0.785714
209 NAD IBO 0.509091 0.87013
210 M24 0.508772 0.85
211 YLY 0.508772 0.809524
212 P1H 0.508333 0.851852
213 5AD 0.506849 0.746479
214 GJV 0.505882 0.75
215 LEU LMS 0.505155 0.761364
216 G A A A 0.504505 0.871795
217 4TA 0.504505 0.807229
218 NAJ PZO 0.504425 0.848101
219 KAA 0.5 0.752809
220 NDC 0.5 0.871795
221 7D7 0.5 0.743243
222 71V 0.5 0.907895
223 A3G 0.5 0.8
224 128 0.5 0.776471
225 GSU 0.5 0.77907
226 N0B 0.495726 0.819277
227 NJP 0.495495 0.945946
228 ODP 0.495495 0.909091
229 2SA 0.494624 0.932432
230 6C6 0.494505 0.881579
231 SFG 0.494382 0.75
232 0WD 0.491071 0.921053
233 YSA 0.490196 0.77907
234 PO4 PO4 A A A A PO4 0.489796 0.902778
235 6IA 0.48913 0.8375
236 SAM 0.48913 0.690476
237 A7D 0.488636 0.776316
238 6FA 0.488 0.841463
239 FB0 0.487805 0.804598
240 NAJ PYZ 0.487179 0.85
241 IDP 0.483516 0.918919
242 A5D 0.483516 0.786667
243 SA8 0.483516 0.707317
244 MHZ 0.483146 0.697674
245 PGS 0.483146 0.883117
246 D5M 0.482353 0.878378
247 DA 0.482353 0.878378
248 NEC 0.482353 0.746667
249 NIA 0.481928 0.822785
250 Y3J 0.480519 0.726027
251 FAD 0.480315 0.851852
252 FAS 0.480315 0.851852
253 FDA 0.48 0.833333
254 N6P 0.479592 0.915493
255 GGZ 0.479167 0.825
256 SAH 0.478261 0.74359
257 SAI 0.478261 0.734177
258 NPW 0.477477 0.886076
259 NDP 0.477477 0.921053
260 AAM 0.476744 0.971429
261 AMZ 0.47561 0.916667
262 C2R 0.47561 0.90411
263 A A A 0.474747 0.905405
264 GTP 0.473684 0.92
265 U A G G 0.473684 0.883117
266 SMM 0.473684 0.686047
267 TXP 0.473214 0.921053
268 NZQ 0.473214 0.909091
269 A3S 0.47191 0.810811
270 AMP NAD 0.470588 0.881579
271 SFD 0.46875 0.734043
272 AIR 0.468354 0.901408
273 AAT 0.468085 0.707317
274 EEM 0.468085 0.690476
275 Z5A 0.466667 0.77907
276 7C5 0.466667 0.818182
277 J7V 0.466667 0.833333
278 62F 0.465649 0.8625
279 FAY 0.462121 0.8625
280 ETB 0.461538 0.833333
281 DCA 0.461538 0.823529
282 A3T 0.461538 0.821918
283 A6D 0.46 0.722892
284 A U 0.459459 0.87013
285 6K6 0.459184 0.930556
286 GEK 0.459184 0.7375
287 RFL 0.458647 0.821429
288 S7M 0.458333 0.690476
289 NAP 0.458333 0.945205
290 4YB 0.457944 0.761364
291 WSA 0.454545 0.788235
292 TAP 0.454545 0.907895
293 FNK 0.454545 0.804598
294 COA 0.453782 0.823529
295 0T1 0.453782 0.823529
296 101 0.453488 0.878378
297 XNP 0.452174 0.873418
298 NA0 0.45082 0.932432
299 7RP 0.448276 0.928571
300 GP3 0.446809 0.921053
301 TM1 0.446602 0.77381
302 APU 0.446429 0.894737
303 PUA 0.445378 0.884615
304 V1N 0.443396 0.917808
305 7RA 0.443182 0.957747
306 30N 0.442623 0.752688
307 CAO 0.442623 0.795455
308 AMX 0.442623 0.833333
309 COS 0.442623 0.804598
310 ACK 0.44186 0.861111
311 QQY 0.44186 0.815789
312 649 0.441441 0.744444
313 0UM 0.44 0.698795
314 NHD 0.439655 0.905405
315 CMX 0.439024 0.823529
316 SCO 0.439024 0.823529
317 GCP 0.438776 0.896104
318 8BR 0.438202 0.906667
319 GNH 0.4375 0.907895
320 3AD 0.4375 0.805556
321 62X 0.435644 0.666667
322 ACO 0.435484 0.795455
323 FCX 0.435484 0.795455
324 FAM 0.435484 0.804598
325 GNP 0.434343 0.896104
326 NMX 0.433071 0.76087
327 MGP 0.43299 0.884615
328 PLP AAD 0.432203 0.741573
329 26A 0.432099 0.763158
330 HAX 0.432 0.804598
331 K15 0.431373 0.682353
332 DG1 0.430894 0.921053
333 1DG 0.430894 0.921053
334 QQX 0.430233 0.805195
335 2VA 0.430108 0.8
336 S8M 0.43 0.759494
337 2MC 0.429688 0.769231
338 3KK 0.428571 0.804598
339 6G0 0.428571 0.884615
340 FYN 0.428571 0.823529
341 P5F 0.428571 0.823529
342 NAD BBN 0.428571 0.841463
343 U G A 0.427481 0.839506
344 AS 0.426966 0.833333
345 FAI 0.426966 0.916667
346 RMB 0.426966 0.873239
347 1RB 0.425287 0.885714
348 MCD 0.425197 0.804598
349 OXK 0.425197 0.804598
350 COK 0.425197 0.804598
351 CA6 0.425197 0.729167
352 SOP 0.425197 0.804598
353 G1R 0.424242 0.907895
354 CC5 0.423077 0.816901
355 SXZ 0.423077 0.710843
356 F2N 0.422535 0.813953
357 NAD CJ3 0.422222 0.811765
358 ANZ 0.422018 0.8
359 CMC 0.421875 0.804598
360 CO6 0.421875 0.804598
361 1VU 0.421875 0.795455
362 ZDA 0.421053 0.864865
363 GDD 0.420561 0.884615
364 GKE 0.420561 0.884615
365 GDC 0.420561 0.884615
366 NFD 0.420168 0.883117
367 GSP 0.42 0.873418
368 D3Y 0.42 0.789474
369 MC4 0.419847 0.76087
370 3L1 0.419753 0.773333
371 3D1 0.419753 0.773333
372 FA9 0.41958 0.864198
373 5GP 0.419355 0.906667
374 G 0.419355 0.906667
375 KB1 0.419048 0.698795
376 SCD 0.418605 0.823529
377 CAJ 0.418605 0.804598
378 2BA 0.417582 0.915493
379 CMP 0.417582 0.901408
380 SO8 0.416667 0.789474
381 N01 0.416667 0.905405
382 VRT 0.416667 0.769231
383 3HC 0.415385 0.813953
384 A1S 0.415385 0.804598
385 BCO 0.415385 0.804598
386 IVC 0.415385 0.813953
387 MLC 0.415385 0.804598
388 1HE 0.415385 0.786517
389 NMN AMP PO4 0.415254 0.87013
390 2FA 0.414634 0.813333
391 MGO 0.414141 0.860759
392 3NZ 0.413462 0.782051
393 MCA 0.412214 0.795455
394 CAA 0.412214 0.813953
395 YE1 0.412214 0.813953
396 COO 0.412214 0.804598
397 GAV 0.411765 0.884615
398 P2P 0.411111 0.902778
399 JLN 0.411111 0.890411
400 ZZB 0.410256 0.77381
401 CNV FAD 0.410072 0.793103
402 SCA 0.409091 0.804598
403 RP1 0.409091 0.842105
404 103 0.409091 0.837838
405 2CP 0.409091 0.795455
406 SP1 0.409091 0.842105
407 PAX 0.408 0.829268
408 FAD NBT 0.407143 0.75
409 NVA 2AD 0.40625 0.74359
410 COW 0.406015 0.795455
411 BYC 0.406015 0.804598
412 2KQ 0.406015 0.786517
413 COF 0.406015 0.786517
414 3CP 0.406015 0.804598
415 IRC 0.406015 0.813953
416 1GZ 0.406015 0.795455
417 HGG 0.406015 0.804598
418 CA8 0.406015 0.729167
419 G2P 0.405941 0.884615
420 SLU 0.404959 0.770115
421 U A C C 0.404959 0.858974
422 RBZ 0.404494 0.849315
423 1CZ 0.404412 0.795455
424 BCA 0.402985 0.795455
425 FAQ 0.402985 0.804598
426 4CA 0.402985 0.795455
427 MTP 0.402439 0.730769
428 8OD 0.402062 0.945205
429 CO7 0.401515 0.804598
430 DAL FAD PER 0.401408 0.809524
431 G2R 0.4 0.884615
432 HXC 0.4 0.786517
433 ENQ 0.4 0.916667
434 GMV 0.4 0.896104
435 GRA 0.4 0.804598
Ligand no: 2; Ligand: ANP; Similar ligands found: 358
No: Ligand ECFP6 Tc MDL keys Tc
1 ANP 1 1
2 A2D 0.810811 0.945205
3 B4P 0.802632 0.945205
4 ADP 0.802632 0.972222
5 AP5 0.802632 0.945205
6 BA3 0.789474 0.945205
7 AU1 0.782051 1
8 ATP 0.772152 0.972222
9 AN2 0.769231 0.986111
10 AQP 0.7625 0.972222
11 5FA 0.7625 0.972222
12 M33 0.759494 0.932432
13 MAP 0.752941 0.972973
14 ACP 0.75 0.945946
15 APR 0.740741 0.945205
16 AR6 0.740741 0.945205
17 ACQ 0.73494 0.945946
18 AD9 0.731707 0.945946
19 SAP 0.731707 0.921053
20 AGS 0.731707 0.921053
21 AMP 0.723684 0.944444
22 A 0.723684 0.944444
23 ATF 0.717647 0.933333
24 ADX 0.716049 0.851852
25 CA0 0.716049 0.92
26 50T 0.707317 0.932432
27 PRX 0.698795 0.87013
28 ABM 0.696203 0.893333
29 AMP MG 0.683544 0.868421
30 AP2 0.679012 0.933333
31 A12 0.679012 0.933333
32 APC 0.678571 0.933333
33 TAT 0.674419 0.933333
34 A22 0.674157 0.958904
35 SRA 0.670886 0.894737
36 SRP 0.670455 0.883117
37 5AL 0.666667 0.906667
38 ADQ 0.659341 0.92
39 A1R 0.659341 0.884615
40 ADP MG 0.654762 0.881579
41 3OD 0.648936 0.92
42 BIS 0.648936 0.909091
43 5SV 0.648352 0.82716
44 BEF ADP 0.647059 0.858974
45 ADP BEF 0.647059 0.858974
46 OAD 0.645161 0.92
47 25L 0.642105 0.958904
48 AMO 0.641304 0.907895
49 G5P 0.636364 0.897436
50 DLL 0.634409 0.906667
51 AHX 0.634409 0.897436
52 00A 0.634409 0.860759
53 ANP MG 0.633333 0.921053
54 ADV 0.632184 0.907895
55 ADP PO3 0.632184 0.917808
56 RBY 0.632184 0.907895
57 NB8 0.631579 0.897436
58 25A 0.630435 0.945205
59 8QN 0.630435 0.906667
60 OOB 0.630435 0.906667
61 G3A 0.626263 0.897436
62 ATP MG 0.625 0.881579
63 4AD 0.623656 0.896104
64 PAJ 0.623656 0.8625
65 LAD 0.621053 0.839506
66 1ZZ 0.614583 0.819277
67 TXA 0.614583 0.907895
68 ME8 0.614583 0.819277
69 GTA 0.613861 0.864198
70 3UK 0.610526 0.894737
71 SON 0.604651 0.907895
72 ADP ALF 0.604396 0.848101
73 ALF ADP 0.604396 0.848101
74 WAQ 0.604167 0.860759
75 PR8 0.604167 0.829268
76 4UV 0.6 0.871795
77 GAP 0.6 0.87013
78 FYA 0.597938 0.881579
79 PTJ 0.597938 0.873418
80 ADP VO4 0.597826 0.906667
81 VO4 ADP 0.597826 0.906667
82 UP5 0.596154 0.896104
83 YAP 0.59596 0.871795
84 FA5 0.59596 0.883117
85 PAP 0.595506 0.958333
86 A4P 0.59434 0.823529
87 XAH 0.59 0.841463
88 4UU 0.588235 0.871795
89 AFH 0.588235 0.8625
90 9SN 0.585859 0.85
91 2A5 0.58427 0.894737
92 T5A 0.583333 0.821429
93 NAI 0.580952 0.884615
94 ITT 0.579545 0.917808
95 ATR 0.577778 0.944444
96 OMR 0.575472 0.831325
97 5AS 0.574713 0.781609
98 YLP 0.571429 0.8
99 48N 0.571429 0.873418
100 AP0 0.570093 0.873418
101 4TC 0.570093 0.873418
102 7D3 0.569767 0.881579
103 ADJ 0.568807 0.831325
104 GNP 0.568421 0.922078
105 DAL AMP 0.568421 0.881579
106 NXX 0.566038 0.907895
107 TXD 0.566038 0.884615
108 NAX 0.566038 0.851852
109 4UW 0.566038 0.839506
110 6V0 0.566038 0.873418
111 DND 0.566038 0.907895
112 XYA 0.565789 0.821918
113 ADN 0.565789 0.821918
114 RAB 0.565789 0.821918
115 AOC 0.564706 0.8
116 7D4 0.561798 0.881579
117 ADP BMA 0.561224 0.894737
118 TXE 0.560748 0.884615
119 TYM 0.560748 0.883117
120 YLB 0.555556 0.8
121 YLC 0.555556 0.819277
122 139 0.554545 0.851852
123 5N5 0.551282 0.797297
124 JB6 0.55 0.860759
125 LAQ 0.54717 0.819277
126 MYR AMP 0.544554 0.797619
127 A4D 0.544304 0.797297
128 5CD 0.544304 0.783784
129 7MD 0.542857 0.864198
130 6AD 0.542553 0.886076
131 A2R 0.541667 0.958904
132 UPA 0.541284 0.884615
133 YLA 0.540541 0.8
134 A A 0.54 0.918919
135 COD 0.539823 0.793103
136 BTX 0.539823 0.821429
137 G5A 0.537634 0.781609
138 CNA 0.535714 0.907895
139 AYB 0.535714 0.790698
140 3DH 0.535714 0.753247
141 BT5 0.535088 0.811765
142 ATP A A A 0.533981 0.905405
143 IOT 0.531532 0.811765
144 MTA 0.53012 0.753247
145 3AM 0.529412 0.90411
146 A3P 0.52809 0.944444
147 NAD 0.526316 0.906667
148 PPS 0.526316 0.851852
149 EP4 0.52439 0.734177
150 7D5 0.52381 0.855263
151 AMP DBH 0.52381 0.87013
152 J7C 0.522727 0.75
153 A5A 0.520833 0.809524
154 EAD 0.520661 0.851852
155 TSB 0.520408 0.821429
156 AHZ 0.518519 0.797619
157 M2T 0.518072 0.716049
158 DTA 0.518072 0.766234
159 A3D 0.517241 0.894737
160 6RE 0.517241 0.740741
161 YLY 0.516949 0.790698
162 SSA 0.515464 0.802326
163 NA7 0.514852 0.933333
164 TYR AMP 0.514286 0.858974
165 AR6 AR6 0.514019 0.893333
166 7MC 0.513514 0.843373
167 A2P 0.511111 0.930556
168 52H 0.510204 0.781609
169 VMS 0.510204 0.790698
170 54H 0.510204 0.790698
171 TAD 0.509259 0.8625
172 NAQ 0.508333 0.85
173 A3N 0.505618 0.766234
174 AV2 0.505155 0.893333
175 5CA 0.50505 0.802326
176 53H 0.50505 0.781609
177 ARU 0.504951 0.839506
178 ARG AMP 0.504587 0.809524
179 ZID 0.504132 0.894737
180 P1H 0.504 0.831325
181 3AT 0.5 0.945205
182 NAE 0.5 0.871795
183 AVV 0.5 0.873418
184 P5A 0.495146 0.747253
185 DSZ 0.49505 0.802326
186 LSS 0.49505 0.764045
187 NSS 0.49505 0.802326
188 N0B 0.491803 0.8
189 AF3 ADP 3PG 0.491071 0.817073
190 LA8 ALF 3PG 0.491071 0.817073
191 ALF ADP 3PG 0.491071 0.817073
192 NVA LMS 0.490196 0.764045
193 DAT 0.489362 0.881579
194 IMO 0.488889 0.90411
195 ZAS 0.488636 0.792208
196 FDA 0.488372 0.813953
197 NAJ PZO 0.487395 0.85
198 4TA 0.487179 0.788235
199 LPA AMP 0.486486 0.797619
200 LEU LMS 0.485437 0.764045
201 DTP 0.484536 0.881579
202 V3L 0.484536 0.945205
203 GJV 0.483516 0.731707
204 S4M 0.483516 0.651685
205 DZD 0.483051 0.8625
206 2AM 0.482759 0.917808
207 5AD 0.481013 0.726027
208 KAA 0.480769 0.755556
209 GSU 0.480769 0.781609
210 NDE 0.480315 0.907895
211 M24 0.479339 0.851852
212 MAO 0.478261 0.761905
213 DSH 0.477778 0.707317
214 NEC 0.477778 0.727273
215 FAD 0.477273 0.831325
216 FAS 0.477273 0.831325
217 RGT 0.476636 0.933333
218 0WD 0.474576 0.897436
219 G A A A 0.474576 0.85
220 FNK 0.474074 0.786517
221 5X8 0.473684 0.74359
222 6FA 0.473282 0.821429
223 FB0 0.472868 0.786517
224 NDC 0.472868 0.85
225 YSA 0.472222 0.781609
226 7DD 0.468085 0.958333
227 OVE 0.466667 0.881579
228 NAD IBO 0.466102 0.848101
229 MHZ 0.463158 0.701149
230 A3G 0.461538 0.779221
231 6C6 0.459184 0.858974
232 U A G G 0.458333 0.860759
233 SFG 0.458333 0.730769
234 7D7 0.45679 0.723684
235 128 0.45614 0.8
236 SFD 0.455224 0.736842
237 DDS 0.454545 0.855263
238 GDP 0.454545 0.896104
239 6IA 0.454545 0.817073
240 NJP 0.453782 0.921053
241 ODP 0.453782 0.886076
242 7DT 0.453608 0.958333
243 A7D 0.452632 0.75641
244 Z5A 0.452381 0.802326
245 WSA 0.452174 0.790698
246 7C5 0.45045 0.797468
247 FAY 0.449275 0.841463
248 NDP 0.449153 0.897436
249 A5D 0.44898 0.766234
250 SA8 0.44898 0.690476
251 NAJ PYZ 0.448 0.851852
252 71V 0.446809 0.884615
253 GGZ 0.446602 0.804878
254 RFL 0.446043 0.802326
255 2SA 0.445545 0.907895
256 AMP NAD 0.444444 0.858974
257 GP3 0.444444 0.897436
258 SAI 0.444444 0.716049
259 SAH 0.444444 0.725
260 A A A 0.443396 0.881579
261 PO4 PO4 A A A A PO4 0.443396 0.878378
262 4YB 0.442478 0.764045
263 GTP 0.441176 0.896104
264 SMM 0.441176 0.670455
265 S7M 0.441176 0.674419
266 Y3J 0.440476 0.706667
267 SAM 0.44 0.674419
268 649 0.439655 0.747253
269 12D 0.438596 0.809524
270 A3S 0.4375 0.789474
271 NPW 0.436975 0.864198
272 GCP 0.436893 0.873418
273 AAT 0.435644 0.690476
274 EEM 0.435644 0.674419
275 GNH 0.435644 0.909091
276 DCA 0.435484 0.804598
277 ETB 0.435484 0.813953
278 N6P 0.433962 0.890411
279 TXP 0.433333 0.897436
280 NZQ 0.433333 0.886076
281 PGS 0.43299 0.860759
282 APU 0.432203 0.871795
283 PUA 0.432 0.8625
284 62F 0.431655 0.841463
285 F2N 0.431507 0.795455
286 DA 0.430108 0.855263
287 D5M 0.430108 0.855263
288 J7V 0.429688 0.813953
289 NIA 0.428571 0.848101
290 6K6 0.428571 0.905405
291 A3T 0.428571 0.8
292 0T1 0.428571 0.804598
293 COA 0.428571 0.804598
294 P5F 0.427586 0.804598
295 AAM 0.425532 0.944444
296 0UM 0.424528 0.682353
297 G1R 0.423077 0.884615
298 AMZ 0.422222 0.891892
299 C2R 0.422222 0.88
300 A U 0.420168 0.848101
301 IDP 0.42 0.894737
302 GSP 0.419048 0.851852
303 COS 0.418605 0.786517
304 CAO 0.418605 0.777778
305 AMX 0.418605 0.813953
306 30N 0.418605 0.736842
307 DG1 0.418605 0.897436
308 1DG 0.418605 0.897436
309 TM1 0.418182 0.797619
310 A6D 0.416667 0.746988
311 K15 0.416667 0.666667
312 V1N 0.415929 0.893333
313 SCO 0.415385 0.804598
314 CMX 0.415385 0.804598
315 GEK 0.415094 0.719512
316 NHD 0.414634 0.881579
317 XNP 0.414634 0.851852
318 AIR 0.413793 0.876712
319 COK 0.413534 0.786517
320 G2R 0.412844 0.8625
321 FCX 0.412214 0.777778
322 FAM 0.412214 0.786517
323 ACO 0.412214 0.777778
324 NAP 0.410853 0.92
325 CNV FAD 0.409722 0.775281
326 FA9 0.409396 0.843373
327 SXZ 0.409091 0.694118
328 HAX 0.409091 0.806818
329 PLP AAD 0.408 0.744444
330 TAP 0.407692 0.884615
331 2MC 0.407407 0.752688
332 62X 0.407407 0.651685
333 GKE 0.40708 0.8625
334 GDD 0.40708 0.8625
335 GDC 0.40708 0.8625
336 FYN 0.406015 0.804598
337 3KK 0.406015 0.786517
338 U G A 0.405797 0.819277
339 NA0 0.40458 0.907895
340 101 0.404255 0.855263
341 G 0.40404 0.883117
342 5GP 0.40404 0.883117
343 MGP 0.403846 0.8625
344 MCD 0.402985 0.786517
345 OXK 0.402985 0.786517
346 CA6 0.402985 0.714286
347 SOP 0.402985 0.786517
348 3AD 0.402299 0.783784
349 S8M 0.401869 0.78481
350 YE1 0.40146 0.795455
351 1VU 0.4 0.777778
352 2VA 0.4 0.779221
353 CMC 0.4 0.786517
354 7RP 0.4 0.902778
355 GMV 0.4 0.873418
356 6G0 0.4 0.8625
357 CO6 0.4 0.786517
358 NMX 0.4 0.782609
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1W5T; Ligand: ANP; Similar sites found: 455
This union binding pocket(no: 1) in the query (biounit: 1w5t.bio1) has 22 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 2BME GNP 0.001389 0.43585 None
2 1Z0A GDP 0.0002726 0.43176 None
3 4LHW GNP 0.001414 0.40443 None
4 5VGR GDP 0.001892 0.43059 0.928074
5 1SVK ALF GDP 0.001094 0.44674 1.13314
6 2VVG ADP 0.00001704 0.40233 1.14286
7 1Y3A GDP 0.001559 0.43017 1.21581
8 1AZT GSP 0.001768 0.43608 1.24378
9 1BH2 GSP 0.001441 0.43998 1.26984
10 2C04 GCP 0.00348 0.41889 1.3468
11 2DPY ADP 0.0003935 0.49452 1.45631
12 5JCP GDP ALF 0.002031 0.42922 1.45631
13 5HR5 ADP 0.001235 0.4203 1.45631
14 1OYY AGS 0.01407 0.40646 1.45631
15 1TAD GDP 0.001384 0.44075 1.54321
16 1Z6T ADP 0.0002687 0.468 1.69903
17 2ZPA ADP 0.00029 0.45194 1.69903
18 4KCT PYR 0.01547 0.40858 1.69903
19 3CPJ GDP 0.001215 0.41495 1.79372
20 3EWA ANP 0.0004485 0.40788 1.86335
21 3CNL GNP 0.0005448 0.40096 1.9084
22 5K5Z ANP 0.0002892 0.43607 1.91083
23 4GOX A3P 0.00311 0.40451 1.91693
24 1XKV ATP 0.0003957 0.42817 1.94175
25 3CV2 OXL 0.01287 0.41786 1.94175
26 1V8K ANP 0.0003877 0.48217 1.95122
27 4AG5 ADP 0.0001689 0.51806 2.04082
28 5H68 AGS 0.0001395 0.41158 2.05882
29 4FRZ ADP 0.00009665 0.40341 2.07254
30 2WKQ GTP 0.001205 0.41748 2.10843
31 2PL3 ADP 0.002914 0.44474 2.11864
32 1ZJ6 G3D 0.0006751 0.46502 2.13904
33 4ZNL BEF ADP 0.0001563 0.49506 2.18978
34 3MGB PAP 0.005299 0.40386 2.19436
35 1D2N ANP 0.0001709 0.46696 2.20588
36 1T8U UAP SGN IDS SGN 0.02072 0.40006 2.20588
37 4WOP CTP 0.003142 0.41348 2.22222
38 3H4S ADP 0.00005098 0.40176 2.22222
39 2Y8E GNP 0.001395 0.40229 2.23464
40 3MD0 GDP 0.000303 0.41011 2.25352
41 2OBM ADP 0.0005611 0.49223 2.30548
42 1AQU A3P 0.003279 0.40348 2.3569
43 1CR1 TTP 0.001131 0.43226 2.36486
44 3ITJ CIT 0.0222 0.4076 2.36686
45 1ZUI SKM 0.004002 0.42829 2.38095
46 4PX9 ADP 0.003079 0.44355 2.39726
47 4WZ6 ATP 0.00002459 0.56342 2.41379
48 2CE7 ADP 0.000001847 0.51832 2.42718
49 5IRN ADP 0.0001171 0.48932 2.42718
50 4PJ3 ANP 0.0001799 0.48089 2.42718
51 2JLR ANP 0.0006928 0.424 2.42718
52 2WHX ADP 0.00007033 0.4158 2.42718
53 4OHY ANP 0.001215 0.41296 2.42718
54 2B8W ALF 5GP 0.002588 0.42249 2.43902
55 1D5C GDP 0.0005713 0.43248 2.46914
56 2C77 GNP 0.002104 0.42085 2.46914
57 2C78 GNP 0.002181 0.41315 2.46914
58 1PUJ GNP 0.0005056 0.42802 2.48227
59 1GOJ ADP 0.00001547 0.58724 2.53521
60 2XTZ GSP 0.002115 0.42796 2.54237
61 2NGR GDP 0.0004155 0.41764 2.6178
62 5MZN ADP 0.0003174 0.49929 2.6699
63 1OS1 ATP 0.00376 0.42168 2.6699
64 1OS1 PYR 0.004047 0.42168 2.6699
65 2ZFI ADP 0.0003178 0.48635 2.73224
66 4YC7 GNP 0.001208 0.43303 2.76243
67 2FNA ADP 0.0001294 0.46414 2.80112
68 1X1R GDP 0.002176 0.42904 2.80899
69 2IYL GDP 0.0002734 0.48952 2.8169
70 1OXV ANP 0.000006952 0.47102 2.83286
71 2QEN ADP 0.00004649 0.47984 2.85714
72 3NKV GNP 0.001724 0.4318 2.85714
73 2AWN ADP 0.000003156 0.62947 2.88714
74 4K91 SIN 0.03822 0.4025 2.89017
75 4LPS GDP 0.00009679 0.5049 2.89256
76 5GOE GDP 0.0007996 0.45647 2.91262
77 2VF7 ADP 0.0001616 0.43396 2.91262
78 1WDT GTP 0.001496 0.43101 2.91262
79 2BCG GDP 0.001675 0.42889 2.91262
80 5I0H ADP BEF 0.00276 0.41586 2.91262
81 1JI0 ATP 0.00002597 0.55476 2.91667
82 1GWN GTP 0.003124 0.41358 2.92683
83 3NHB ADP 0.00006388 0.54087 2.94118
84 1GRN GDP 0.002023 0.4293 2.95567
85 3COB ADP 0.0001535 0.40937 2.98103
86 1WF3 GNP 0.0022 0.42883 2.99003
87 2J5V PCA 0.04173 0.40482 2.99728
88 3B7G ANP 0.00816 0.41379 3.04348
89 3DEF GDP 0.0001981 0.479 3.05344
90 2PZE ATP 0.00002059 0.41162 3.05677
91 4YDS ATP 0.00009397 0.52626 3.07018
92 5H56 ADP 0.001654 0.43883 3.07692
93 5H56 TYD 0.001654 0.43883 3.07692
94 3REF GDP 0.003714 0.40421 3.09278
95 1OW3 GDP 0.001199 0.4192 3.10881
96 4MGA 27L 0.0201 0.40145 3.13725
97 2A5J GDP 0.0004337 0.46874 3.14136
98 4PFO ADP 0.002438 0.42528 3.15534
99 5TSH ANP 0.0002612 0.42312 3.15534
100 3IX9 MTX 0.007199 0.40492 3.15789
101 5KUT GDP 0.0001003 0.44482 3.1746
102 5HPY GDP 0.001749 0.41304 3.24324
103 1YZN GNP 0.0008007 0.40727 3.24324
104 5IRR GSP 0.0007237 0.43318 3.24675
105 1KMQ GNP 0.003522 0.41502 3.26087
106 1M7B GTP 0.003129 0.41355 3.26087
107 1FZQ GDP 0.0009695 0.40065 3.31492
108 1RRC ADP 0.00004659 0.40425 3.32226
109 1G6O ADP 0.0003151 0.47514 3.33333
110 1Z0F GDP 0.0001279 0.43738 3.35196
111 2Z5F A3P 0.003887 0.40956 3.3557
112 2GWH A3P 0.005878 0.40882 3.3557
113 3ZQ6 ADP ALF 0.0007754 0.44853 3.39506
114 2GDJ ANP 0.0003311 0.48549 3.40909
115 5GVR LMR 0.0007166 0.47552 3.4188
116 2QZ4 ADP 0.00000107 0.528 3.43511
117 5HCN GCP 0.001055 0.45585 3.44828
118 1RYH GNP 0.001275 0.40627 3.44828
119 4V03 ADP 0.000272 0.47809 3.50195
120 5J1J ANP 0.0001978 0.44845 3.50877
121 4D81 ADP 0.000002898 0.56179 3.53357
122 3GJ0 GDP 0.0004103 0.48098 3.61991
123 1R6B ADP 0.0000002468 0.54217 3.64078
124 2FAH GDP 0.0004459 0.43155 3.64078
125 2BIF ANP 0.003997 0.42587 3.64078
126 2BIF SIN 0.006588 0.42587 3.64078
127 3LXR GDP 0.001265 0.44726 3.64583
128 1E96 GTP 0.002304 0.42635 3.64583
129 3WYF GTP 0.001856 0.43363 3.65297
130 3M1I GTP 0.001778 0.43286 3.65297
131 1H65 GDP 0.0004784 0.45014 3.7037
132 1ION ADP 0.0001686 0.44104 3.7037
133 5BXQ GDP 0.0007225 0.40961 3.7037
134 3CH5 GDP 0.0009015 0.4045 3.7037
135 3IA4 MTX 0.01201 0.40204 3.7037
136 1M7G AV2 0.0002133 0.41523 3.79147
137 1M7G ADX 0.006624 0.41355 3.79147
138 1M7G ADP 0.01081 0.40149 3.79147
139 1G3Q ADP 0.0002216 0.48789 3.79747
140 3AQ4 GDP 0.0005277 0.47008 3.80435
141 1XP8 AGS 0.0005316 0.40269 3.82514
142 2OFW ADX 0.002551 0.4406 3.84615
143 2IS6 ADP 0.00001744 0.46625 3.8835
144 2RCN GDP 0.0002186 0.42285 3.91061
145 2FJU GSP 0.004453 0.40706 3.93258
146 1XTQ GDP 0.0005454 0.4497 3.9548
147 4XTR ADP 0.0006733 0.44599 3.9548
148 4XTR ATP 0.001021 0.42056 3.9548
149 4XVU ATP 0.001319 0.41652 3.9548
150 3UIE ANP 0.0007458 0.41571 4
151 4D0N GDP 0.0006286 0.40486 4.02145
152 3IO3 ADP 0.001525 0.42166 4.02299
153 4YLG GDP 0.0007216 0.44907 4.04624
154 1UPT GTP 0.00355 0.41309 4.09357
155 5EE5 GTP 0.002602 0.41031 4.09357
156 1SVI GDP 0.0003542 0.40947 4.10256
157 4XSH GSP 0.00307 0.41751 4.10959
158 1YZQ GNP 0.001895 0.43166 4.11765
159 5FTB ANP 0.00002751 0.52403 4.12621
160 5FHD ADP ALF 0.0000372 0.49497 4.12621
161 4J0Q GDP 0.0004159 0.48679 4.12621
162 5LTJ ADP 0.0002907 0.42599 4.12621
163 2WMO GTP 0.001958 0.40014 4.12621
164 3FB4 AP5 0.001183 0.45694 4.16667
165 1R0X ATP 0.00003827 0.43684 4.1958
166 1YRB GDP 0.0006545 0.45559 4.19847
167 2X77 GDP 0.002061 0.4421 4.2328
168 1L2T ATP 0.0003536 0.43081 4.25532
169 3E70 GDP 0.001538 0.40048 4.26829
170 3QBT GNP 0.001656 0.4005 4.28571
171 3N5C GDP 0.0004866 0.47739 4.32099
172 3RWO GDP 0.001059 0.44095 4.32432
173 2RGX AP5 0.001491 0.45455 4.36893
174 5XDR ADP 0.00315 0.43338 4.36893
175 3FKQ ATP 0.001695 0.4327 4.36893
176 3GJX GTP 0.002202 0.42882 4.36893
177 1MKY GDP 0.0001949 0.42488 4.36893
178 3WYG GTP 0.002712 0.42642 4.3956
179 3TNF GNP 0.002532 0.42773 4.42708
180 4ITR GDP 0.004409 0.40228 4.43038
181 4P4T GDP 0.003509 0.415 4.44444
182 2PEZ DAT 0.004688 0.42151 4.46927
183 3LRE ADP 0.00002093 0.58028 4.50704
184 2F9L GDP 0.002155 0.40752 4.52261
185 1DDU DDU 0.02189 0.40102 4.5283
186 4HSE ADP 0.000002174 0.58283 4.53401
187 4MKF AP5 0.001172 0.45824 4.60829
188 1S3G AP5 0.001478 0.45253 4.60829
189 2C9O ADP 0.0000002228 0.58895 4.61165
190 5GJC ATP 0.0001549 0.50148 4.61165
191 4LYA ATP 0.0003735 0.47718 4.61165
192 4XGU ADP 0.000252 0.46924 4.61165
193 3PQC GDP 0.0009506 0.453 4.61538
194 1QF9 C5P 0.002706 0.43714 4.63918
195 1OIX GDP 0.002528 0.4246 4.71204
196 1A4R GDP 0.002084 0.41582 4.71204
197 1OIV GDP 0.004329 0.41448 4.71204
198 1A4R GNH 0.001796 0.41328 4.71204
199 3QKT ANP 0.0003664 0.45903 4.71976
200 3KJI ADP 0.001523 0.4112 4.72441
201 1YVD GNP 0.001452 0.40248 4.73373
202 3FVQ ATP 0.0005705 0.44483 4.73538
203 1G3M PCQ 0.008964 0.41575 4.7619
204 1BO4 COA 0.01739 0.40198 4.7619
205 3X1Z GNP 0.0007257 0.40752 4.79042
206 5X40 ACP 0.0005802 0.44855 4.79452
207 3ZS9 ADP ALF 0.001225 0.40089 4.80226
208 3VX3 ADP 0.001973 0.42582 4.83871
209 1FP6 ADP 0.0001563 0.48365 4.84429
210 3VMF GTP 0.001542 0.4339 4.85437
211 3WYA GDP 0.0001481 0.42868 4.85437
212 3WXM GTP 0.00257 0.42429 4.85437
213 1Y63 ADP 0.0002833 0.4178 4.8913
214 3B5J 12D 0.00007772 0.53047 4.93827
215 5MVR ADP 0.0000895 0.43229 4.93827
216 3SFV GDP 0.001751 0.42423 4.94186
217 1KY3 GDP 0.0005757 0.42735 4.94506
218 3B9Q MLI 0.0005001 0.50749 4.96689
219 1MR3 G3D 0.0005536 0.41705 4.97238
220 3A4M ADP 0.00007532 0.42182 5
221 4LJ9 ACP 0.000002308 0.50134 5.01475
222 2QG6 NMN 0.009276 0.40304 5.02513
223 5JCZ GDP 0.001488 0.43111 5.02793
224 3T1O GDP 0.0006174 0.41886 5.05051
225 4WZA ACP 0.002954 0.45484 5.07246
226 4WZA ADP 0.003716 0.45007 5.07246
227 3U6B GDP 0.0001867 0.50407 5.07614
228 5JBQ GDP 0.0003613 0.48365 5.07614
229 4G5G GDP 0.0004638 0.4784 5.07614
230 3U6K GDP 0.0005688 0.4741 5.07614
231 4PC3 GDP 0.001968 0.434 5.07614
232 4P3Y GDP 0.0002813 0.41071 5.07614
233 4LX0 BEF GDP 0.002786 0.42437 5.08475
234 2BVN GNP 0.0007549 0.45279 5.08906
235 1D8T GDP 0.0004432 0.41067 5.08906
236 4DCT GDP 0.0005839 0.468 5.09709
237 3P4X ADP 0.0001957 0.41789 5.09709
238 4EIL FOL 0.004481 0.41403 5.09709
239 4IHQ ADP 0.0007187 0.40073 5.09709
240 2IXE ATP 0.0004726 0.45037 5.16605
241 4C4P GNP 0.002639 0.42539 5.20231
242 2CJW GDP 0.00007533 0.51664 5.20833
243 4OI4 ATP 0.001053 0.43746 5.21739
244 2HV8 GTP 0.002131 0.42781 5.23256
245 5M04 GDP 0.0004362 0.48576 5.27778
246 4GOJ GNP 0.005371 0.40542 5.29101
247 1Z08 GNP 0.002954 0.40316 5.29412
248 1VG8 GNP 0.001212 0.4401 5.31401
249 1VG0 GDP 0.0006033 0.42591 5.31401
250 1ZD9 GDP 0.001515 0.43077 5.31915
251 5N69 ADP 0.0004953 0.46105 5.33981
252 1M2O GNP 0.003014 0.42129 5.33981
253 3BD9 A3P 0.01309 0.40404 5.35714
254 4KVG GTP 0.0005404 0.45359 5.38462
255 2QTV GNP 0.002245 0.42515 5.38922
256 2D7C GTP 0.002598 0.42409 5.38922
257 3DDC GNP 0.001501 0.43606 5.42169
258 1WQ1 GDP 0.001038 0.42037 5.42169
259 1O3Y GTP 0.003715 0.41402 5.42169
260 2J59 GTP 0.003195 0.40666 5.42169
261 2ZPT A3P 0.01978 0.41178 5.42373
262 4FCW ADP 0.000002781 0.50862 5.46624
263 2GCO GNP 0.002144 0.40912 5.47264
264 2GCN GDP 0.005241 0.40588 5.47264
265 1S9D GDP 0.0004533 0.4732 5.4878
266 1RE0 GDP 0.000212 0.41429 5.4878
267 3EZ2 ADP 0.0001606 0.50732 5.52764
268 4R98 GNH 0.002692 0.44138 5.53506
269 3I6B KDO 0.008211 0.42712 5.55556
270 2G77 GDP 0.002322 0.42665 5.55556
271 1NRJ GTP 0.003047 0.41404 5.6962
272 5CK5 GDP 0.0004208 0.40458 5.6962
273 3ZFD ANP 0.0006404 0.417 5.69801
274 2A5F GTP 0.002419 0.42375 5.69948
275 4PPF FLC 0.00003871 0.5525 5.71429
276 1B0U ATP 0.0004581 0.46258 5.72519
277 2ZR9 DTP 0.0007192 0.46917 5.73066
278 2HT6 GDP 0.00005204 0.43347 5.74713
279 1CXZ GSP 0.001839 0.42526 5.81395
280 5M7P ADP 0.000002415 0.53755 5.82524
281 4IDN GNP 0.003572 0.40487 5.82524
282 1R4A GNP 0.001577 0.43175 5.88235
283 5L3W GDP 0.001321 0.40765 5.88235
284 3Q85 GNP 0.0001533 0.42696 5.91716
285 1HE1 GDP 0.002317 0.41908 5.92593
286 4LC1 GDP 0.0004202 0.48048 5.93472
287 1VG1 GDP 0.0002243 0.42895 5.94595
288 1VG9 GDP 0.0004515 0.41663 5.94595
289 2ZTS ADP 0.002089 0.42474 5.9761
290 4DKX GDP 0.0002841 0.48871 6.01852
291 5LB3 ADP 0.001744 0.45584 6.06796
292 1NVV GNP 0.0009291 0.44512 6.06796
293 1QHG ATP 0.0009751 0.42024 6.06796
294 1ZCB GDP 0.001985 0.42914 6.07735
295 3AB3 GDP 0.001401 0.42833 6.07735
296 3RLF ANP 0.0001801 0.47029 6.08108
297 1FQJ GDP 0.0007762 0.42524 6.12245
298 1FQK GDP 0.001087 0.41958 6.12245
299 4K81 GTP 0.000192 0.47667 6.20155
300 1JJV ATP 0.00003891 0.42038 6.31068
301 1K6M AGS 0.002544 0.40685 6.31068
302 5BQ5 ADP BEF 0.00001846 0.53203 6.34921
303 2FFQ GSP 0.001341 0.43819 6.43275
304 3CX8 GSP 0.002153 0.43232 6.50888
305 3RAB GNP 0.002403 0.42555 6.50888
306 4TTQ ATP 0.0003165 0.41875 6.51163
307 3Q9L ATP 0.000709 0.4494 6.53846
308 3T12 GDP ALF 0.001918 0.41544 6.61765
309 2HF9 GSP 0.0004603 0.45769 6.63717
310 4XOI GTP 0.001701 0.40568 6.66667
311 1JWY GDP 0.0005013 0.42837 6.79612
312 1JWY ADP 0.0003811 0.41862 6.79612
313 3W5J GDP 0.00006947 0.40041 6.86275
314 1UKZ ADP 0.004201 0.42491 6.89655
315 1G8S MET 0.0112 0.42547 6.95652
316 1YQT ADP 0.0000645 0.40913 7.03884
317 1LVG ADP 0.00007628 0.42146 7.07071
318 4HDO GNP 0.0009532 0.44463 7.14286
319 4HDQ GNP 0.001196 0.44035 7.14286
320 2CBZ ATP 0.0000007735 0.65671 7.173
321 5E5U MLI 0.003677 0.40129 7.19697
322 1NVU GTP 0.0009942 0.44384 7.22892
323 4E03 ADP 0.0001544 0.43729 7.28155
324 4U5X GNP 0.002686 0.41087 7.30337
325 2WJG GDP 0.0006 0.47298 7.44681
326 4RZ3 ADP 0.001923 0.43028 7.45763
327 5IFS ADP 0.0000009117 0.5309 7.52427
328 1W0J ADP BEF 0.0001162 0.46785 7.52427
329 1YTM ATP 0.001594 0.42595 7.52427
330 1W0J ADP 0.0007916 0.42185 7.52427
331 3BC1 GNP 0.0009512 0.44297 7.69231
332 3Q72 GNP 0.00007973 0.4269 7.83133
333 2J0V GDP 0.001215 0.40134 8.01887
334 4HI0 GDP 0.0002863 0.45749 8.0402
335 1SQ5 ADP 0.0002296 0.48717 8.11688
336 3A1S GDP 0.001217 0.45292 8.13953
337 4R43 GDP 0.0003382 0.48504 8.25243
338 2OM2 GDP 0.001307 0.4296 8.33333
339 2W58 ADP 0.0000001901 0.69041 8.41584
340 1JJ7 ADP 0.000005621 0.59652 8.46154
341 4NON GDP 0.001602 0.45231 8.46154
342 3T5G GDP 0.0001163 0.44529 8.55263
343 4R2I ANP 0.004453 0.44072 8.57143
344 3FWY ADP 0.0002659 0.44667 8.59873
345 1W7J ADP BEF 0.001607 0.43372 8.60927
346 2OZE AGS 0.0001041 0.46974 8.72483
347 2GK6 ADP 0.00006444 0.43116 8.73786
348 3TMK T5A 0.009636 0.40369 8.7963
349 1G6H ADP 0.00001227 0.58797 8.94942
350 5G41 AP5 0.001008 0.46554 8.96861
351 1LFD GNP 0.00167 0.43239 9.1954
352 3BFV ADP 0.0002223 0.49388 9.22509
353 3KTA AP5 0.0001128 0.49004 9.24856
354 2C5L GTP 0.0004699 0.45799 9.24856
355 1XEX ATP 0.0003712 0.42359 9.30233
356 4KAX GTP 0.003161 0.41524 9.31677
357 3TKL GTP 0.001301 0.40964 9.3633
358 3H86 AP5 0.01331 0.40362 9.375
359 1DS6 GDP 0.0007806 0.40104 9.44444
360 5KSP GDP 0.0003507 0.47847 9.47368
361 4CVN ADP 0.0001681 0.51337 9.48905
362 5TB5 GDP 0.0006651 0.46016 9.70874
363 5TAR GDP 0.0007321 0.45339 9.70874
364 1TQ4 GDP 0.001696 0.42482 9.70874
365 5UQW GDP 0.0009443 0.41555 9.70874
366 5O2T GSP 0.0004655 0.4151 9.70874
367 1GP2 GDP 0.002035 0.40945 9.85915
368 3KUD GDP 0.0009419 0.43562 9.87654
369 1GUA GNP 0.000601 0.41101 9.87654
370 3IIJ ADP 0.0001976 0.42283 10
371 4P32 ADP 0.001343 0.43106 10.0402
372 1F6B GDP 0.001153 0.40269 10.101
373 1S8F GDP 0.00182 0.434 10.1695
374 1IHU ADP 0.0003193 0.45965 10.1942
375 1IHU AF3 0.0003233 0.45739 10.1942
376 1OFH ADP 0.0000007971 0.53351 10.3448
377 2NCD ADP 0.0001223 0.5264 10.4369
378 2EFE GNH 0.001044 0.41739 10.4972
379 5H67 ATP 0.0004631 0.47276 10.5528
380 4H1V GNP 0.006073 0.4082 10.5691
381 1NN5 ANP 0.003613 0.42523 10.6977
382 1NN5 2DT 0.03707 0.40502 10.6977
383 1Z2A GDP 0.001639 0.41241 10.7143
384 4TMZ GSP 0.002699 0.40274 10.7246
385 1KAO GDP 0.0004475 0.43726 10.7784
386 4BQS ADP 0.0001455 0.50279 10.7955
387 3ZIA ADP 0.0006754 0.42483 10.8696
388 3ZIA ATP 0.0005105 0.41652 10.8696
389 1TU3 GNP 0.001741 0.43161 11.1111
390 1R2Q GNP 0.001984 0.44076 11.1765
391 1G16 GDP 0.003078 0.41573 11.1765
392 4IOK ADP 0.00873 0.4042 11.4078
393 1VHT BA3 0.00122 0.40833 11.4679
394 2W83 GTP 0.00325 0.40012 11.6883
395 1KO8 6PG 0.001966 0.41755 12
396 2W2X GSP 0.001422 0.42805 12.0968
397 4DSU GDP 0.001814 0.43248 12.1359
398 4A4Z ANP 0.008955 0.41603 12.1359
399 5WDR GNP 0.001115 0.40222 12.2807
400 4MKG AP5 0.0007155 0.46689 12.4424
401 1XMV ADP 0.0009639 0.4045 12.6404
402 1G4U GDP 0.001146 0.43601 12.7937
403 5J1S ATP 0.00009412 0.45678 12.9707
404 1G41 ADP 0.0000009092 0.53142 13.1068
405 2UZI GTP 0.0002908 0.46523 13.1579
406 1ZC3 GNP 0.000588 0.45376 13.2743
407 5L3R GCP 0.0003031 0.43504 13.289
408 5KSZ GCP 0.0004357 0.46865 13.3495
409 2A9K GDP 0.0004651 0.43633 13.369
410 2XTN GTP 0.002358 0.40664 13.6752
411 2CK3 ANP 0.000114 0.47929 13.6986
412 2V7Q ADP 0.000008126 0.47538 13.6986
413 2CK3 ADP 0.00008914 0.46209 13.6986
414 2V7Q ATP 0.0006615 0.41878 13.6986
415 3QF7 ANP 0.000058 0.47979 14
416 2FH5 GTP 0.003746 0.41024 14.0541
417 1UAD GNP 0.0009352 0.44329 14.2857
418 2ZEJ GDP 0.007112 0.40664 14.6739
419 5KDO GDP 0.001099 0.43279 14.8649
420 1U8Z GDP 0.0003872 0.43662 14.881
421 2D7D ADP 0.0002675 0.42279 15
422 1GOT GDP 0.001635 0.42743 15.0685
423 4U00 ADP 0.00002132 0.4027 15.1639
424 4QM7 GTP 0.0006058 0.40906 15.2047
425 1B7T ADP 0.001039 0.45122 15.3846
426 4BAS GNP 0.002389 0.42042 16.0804
427 2EW1 GNP 0.001919 0.42631 16.4179
428 4YMU ATP 0.00005841 0.52915 16.6667
429 2Q2Y ADP 0.01384 0.40813 16.8937
430 2Q2Y MKR 0.01347 0.40766 16.8937
431 1KK8 BEF ADP 0.002139 0.42823 17.2662
432 1Z0K GTP 0.003277 0.40045 17.3913
433 1GXU 2HP 0.0003075 0.49775 17.5824
434 1HTW ADP 0.0001661 0.43182 17.7215
435 1KSH GDP 0.004754 0.40586 17.7419
436 1UJ2 C5P 0.00521 0.41253 17.8571
437 1UJ2 ADP 0.006365 0.40874 17.8571
438 1NF3 GNP 0.00127 0.40536 18.75
439 5SZH GNP 0.00208 0.42989 19.6078
440 5L3V GDP 0.00124 0.44767 19.7324
441 5L3S GNP 0.0002051 0.4417 19.7987
442 1QHH ATP 0.0008677 0.45987 21.7391
443 5E95 GDP 0.0004181 0.45953 22.6804
444 3WY9 GDP 0.0002426 0.49842 25
445 3DOE GTP 0.004004 0.41263 25.5208
446 4D0G GTP 0.0007397 0.44209 26.087
447 1YZG GDP 0.000561 0.41482 26.8156
448 4V0K GDP 0.003854 0.41324 28.4024
449 1EK0 GNP 0.001395 0.43577 28.8235
450 5XCO GDP 0.0005818 0.42653 29.2398
451 5UFQ GNP 0.001113 0.40614 30.1205
452 1NJF AGS 0.00000111 0.56221 36
453 1NJF ADP 0.000001227 0.54973 36
454 2WIC GNP 0.0003319 0.4796 37.8277
455 1FNN ADP 0.00000000001149 0.78143 47.5578
Pocket No.: 2; Query (leader) PDB : 1W5T; Ligand: ADP; Similar sites found: 426
This union binding pocket(no: 2) in the query (biounit: 1w5t.bio3) has 20 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1Z0A GDP 0.0007278 0.43092 None
2 2BME GNP 0.003265 0.42713 None
3 5VGR GDP 0.004606 0.40959 0.928074
4 1SVK ALF GDP 0.002346 0.43975 1.13314
5 2VVG ADP 0.00004544 0.40582 1.14286
6 1Y3A GDP 0.002811 0.42668 1.21581
7 1AZT GSP 0.002055 0.44092 1.24378
8 1BH2 GSP 0.001825 0.44328 1.26984
9 2C04 GCP 0.003636 0.41407 1.3468
10 2DPY ADP 0.0003987 0.48973 1.45631
11 5HR5 ADP 0.003103 0.41708 1.45631
12 5JCP GDP ALF 0.004488 0.41008 1.45631
13 1TAD GDP 0.001997 0.4415 1.54321
14 2ZPA ADP 0.0002422 0.46774 1.69903
15 1Z6T ADP 0.0004229 0.45482 1.69903
16 3CPJ GDP 0.001784 0.42158 1.79372
17 3TK1 GDP 0.0005742 0.40899 1.81818
18 4GBM A3P 0.001031 0.41365 1.85759
19 3EWA ANP 0.001232 0.40827 1.86335
20 3CNL GNP 0.000746 0.40999 1.9084
21 5K5Z ANP 0.000548 0.41393 1.91083
22 4GOX A3P 0.00112 0.41294 1.91693
23 1XKV ATP 0.00135 0.42069 1.94175
24 1V8K ANP 0.0008728 0.46078 1.95122
25 4AG5 ADP 0.0001452 0.51689 2.04082
26 4FRZ ADP 0.0003056 0.4017 2.07254
27 2PL3 ADP 0.00969 0.415 2.11864
28 1ZJ6 G3D 0.001722 0.44164 2.13904
29 1T9D P22 0.01573 0.40899 2.18447
30 4ZNL BEF ADP 0.0002558 0.48034 2.18978
31 3MGB PAP 0.001847 0.43105 2.19436
32 1D2N ANP 0.0002615 0.46852 2.20588
33 1T8U UAP SGN IDS SGN 0.02261 0.40411 2.20588
34 1T8U A3P 0.007908 0.40312 2.20588
35 4WOP CTP 0.002431 0.40741 2.22222
36 3H4S ADP 0.0001123 0.40697 2.22222
37 3MD0 GDP 0.0006067 0.41426 2.25352
38 2OBM ADP 0.0003636 0.49878 2.30548
39 1AQU A3P 0.001345 0.43292 2.3569
40 1CR1 TTP 0.00189 0.43061 2.36486
41 4PX9 ADP 0.005525 0.42703 2.39726
42 4WZ6 ATP 0.00008251 0.53058 2.41379
43 2CE7 ADP 0.000005357 0.52191 2.42718
44 5IRN ADP 0.0001551 0.47907 2.42718
45 4PJ3 ANP 0.0003416 0.46379 2.42718
46 2JLR ANP 0.004784 0.4035 2.42718
47 2B8W ALF 5GP 0.00447 0.41935 2.43902
48 1D5C GDP 0.001283 0.43381 2.46914
49 2C77 GNP 0.002392 0.42609 2.46914
50 3DFR MTX 0.01072 0.40443 2.46914
51 1PUJ GNP 0.001064 0.4307 2.48227
52 1GOJ ADP 0.00004771 0.55337 2.53521
53 2XTZ GSP 0.0031 0.42815 2.54237
54 2NGR GDP 0.001191 0.41528 2.6178
55 5WRJ A3P 0.003301 0.42527 2.64026
56 5MZN ADP 0.0004768 0.48581 2.6699
57 1OS1 PYR 0.00441 0.42714 2.6699
58 1OS1 ATP 0.004111 0.42714 2.6699
59 2ZFI ADP 0.0008642 0.46098 2.73224
60 2AX9 BHM 0.02156 0.40605 2.73438
61 4YC7 GNP 0.00307 0.42317 2.76243
62 2FNA ADP 0.0002486 0.44251 2.80112
63 1X1R GDP 0.00324 0.42887 2.80899
64 2IYL GDP 0.0003028 0.4828 2.8169
65 1OXV ANP 0.00006663 0.45043 2.83286
66 2QEN ADP 0.0001074 0.48076 2.85714
67 3NKV GNP 0.002976 0.42895 2.85714
68 2AWN ADP 0.000009608 0.59345 2.88714
69 4LPS GDP 0.0003114 0.47635 2.89256
70 5GOE GDP 0.001659 0.43766 2.91262
71 2VF7 ADP 0.0004458 0.43366 2.91262
72 5I0H ADP BEF 0.003704 0.4177 2.91262
73 2BCG GDP 0.002722 0.41218 2.91262
74 1WDT GTP 0.003773 0.40648 2.91262
75 1JI0 ATP 0.0004731 0.48598 2.91667
76 1GWN GTP 0.004316 0.41476 2.92683
77 3NHB ADP 0.0001868 0.51168 2.94118
78 1GRN GDP 0.004063 0.41196 2.95567
79 3COB ADP 0.0001613 0.40221 2.98103
80 1WF3 GNP 0.003303 0.42849 2.99003
81 3DEF GDP 0.0002952 0.46661 3.05344
82 2PZE ATP 0.0000682 0.41461 3.05677
83 4YDS ATP 0.0001449 0.51193 3.07018
84 5H56 TYD 0.002746 0.4366 3.07692
85 5H56 ADP 0.002746 0.4366 3.07692
86 1OW3 GDP 0.002733 0.41948 3.10881
87 2A5J GDP 0.001065 0.44645 3.14136
88 4PFO ADP 0.003315 0.42683 3.15534
89 5TSH ANP 0.000732 0.41883 3.15534
90 4I4B NAD 0.03766 0.40705 3.15534
91 3IX9 MTX 0.0131 0.40035 3.15789
92 5KUT GDP 0.0001802 0.45029 3.1746
93 5HPY GDP 0.003921 0.41264 3.24324
94 5IRR GSP 0.0008976 0.4189 3.24675
95 1KMQ GNP 0.005565 0.41341 3.26087
96 1RRC ADP 0.00009145 0.41036 3.32226
97 1G6O ADP 0.000476 0.4624 3.33333
98 1Z0F GDP 0.0003755 0.4356 3.35196
99 2Z5F A3P 0.001278 0.43811 3.3557
100 2GWH A3P 0.002575 0.42061 3.3557
101 3ZQ6 ADP ALF 0.0008372 0.45552 3.39506
102 2GDJ ANP 0.0006283 0.46762 3.40909
103 5GVR LMR 0.001803 0.43551 3.4188
104 2QZ4 ADP 0.000005598 0.52186 3.43511
105 5HCN GCP 0.002974 0.43053 3.44828
106 1RYH GNP 0.003341 0.40385 3.44828
107 4V03 ADP 0.0003909 0.46631 3.50195
108 5J1J ANP 0.0008048 0.41338 3.50877
109 4D81 ADP 0.0000136 0.52619 3.53357
110 3GJ0 GDP 0.001049 0.45694 3.61991
111 1R6B ADP 0.0000002904 0.56372 3.64078
112 2FAH GDP 0.0007914 0.43647 3.64078
113 2BIF ANP 0.006497 0.42323 3.64078
114 2BIF SIN 0.01035 0.42323 3.64078
115 1E96 GTP 0.002743 0.43055 3.64583
116 3LXR GDP 0.002409 0.43026 3.64583
117 5DCH 1YO 0.02221 0.40174 3.64583
118 3M1I GTP 0.003241 0.42886 3.65297
119 3WYF GTP 0.003931 0.42657 3.65297
120 1H65 GDP 0.0003859 0.46317 3.7037
121 1ION ADP 0.0001745 0.45746 3.7037
122 3CH5 GDP 0.001464 0.41145 3.7037
123 5BXQ GDP 0.001587 0.41048 3.7037
124 4KFU ACP 0.0005365 0.40309 3.77358
125 1M7G AV2 0.0007473 0.41191 3.79147
126 1M7G ADX 0.01257 0.40744 3.79147
127 1G3Q ADP 0.0001644 0.48931 3.79747
128 3AQ4 GDP 0.001259 0.448 3.80435
129 1XP8 AGS 0.0006712 0.41178 3.82514
130 2OFW ADX 0.00756 0.42579 3.84615
131 2IS6 ADP 0.00003512 0.47266 3.8835
132 2RCN GDP 0.0003744 0.428 3.91061
133 2FJU GSP 0.008546 0.40163 3.93258
134 1XTQ GDP 0.001331 0.44118 3.9548
135 4XTR ADP 0.0005802 0.44043 3.9548
136 4XTR ATP 0.0007472 0.41448 3.9548
137 4XVU ATP 0.0009502 0.41108 3.9548
138 3UIE ANP 0.001807 0.41558 4
139 4D0N GDP 0.001897 0.40113 4.02145
140 3IO3 ADP 0.0009847 0.44101 4.02299
141 1F9V ADP 0.0003002 0.40407 4.03458
142 4YLG GDP 0.002203 0.42357 4.04624
143 1UPT GTP 0.004382 0.4163 4.09357
144 1SVI GDP 0.0006719 0.41274 4.10256
145 1YZQ GNP 0.003437 0.42771 4.11765
146 5FTB ANP 0.00004677 0.50837 4.12621
147 4J0Q GDP 0.0005901 0.47482 4.12621
148 5FHD ADP ALF 0.0002587 0.44797 4.12621
149 5LTJ ADP 0.0009922 0.42051 4.12621
150 3FB4 AP5 0.001585 0.45907 4.16667
151 1R0X ATP 0.00005693 0.44659 4.1958
152 1YRB GDP 0.001477 0.43543 4.19847
153 2X77 GDP 0.006414 0.41491 4.2328
154 3E70 GDP 0.001833 0.4101 4.26829
155 3N5C GDP 0.0009984 0.45798 4.32099
156 3RWO GDP 0.002077 0.43601 4.32432
157 3KDU NKS 0.01592 0.41042 4.33213
158 3LKZ SFG 0.009227 0.40015 4.36137
159 2RGX AP5 0.00159 0.46119 4.36893
160 1MKY GDP 0.0005173 0.42439 4.36893
161 3GJX GTP 0.004839 0.42096 4.36893
162 3FKQ ATP 0.00384 0.41304 4.36893
163 5XDR ADP 0.00721 0.41252 4.36893
164 3WYG GTP 0.004119 0.42565 4.3956
165 3TNF GNP 0.003384 0.42954 4.42708
166 4ITR