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Receptor
PDB id Resolution Class Description Source Keywords
1W8D 2.2 Å EC: 1.3.1.34 BINARY STRUCTURE OF HUMAN DECR. HOMO SAPIENS SHORT CHAIN DEHYDROGENASE REDUCTASE SELENOMETHIONINE SAD DIENOYL-COA OXIDOREDUCTASE
Ref.: STRUCTURE AND REACTIVITY OF HUMAN MITOCHONDRIAL 2,4-DIENOYL-COA REDUCTASE: ENZYME-LIGAND INTERACTIONS IN A DISTINCTIVE SHORT-CHAIN REDUCTASE ACTIVE SITE J.BIOL.CHEM. V. 280 3068 2005
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GOL A:1329;
D:1328;
Invalid;
Invalid;
none;
none;
submit data
92.094 C3 H8 O3 C(C(C...
NAP A:1330;
B:1330;
C:1329;
D:1329;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
submit data
743.405 C21 H28 N7 O17 P3 c1cc(...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1W8D 2.2 Å EC: 1.3.1.34 BINARY STRUCTURE OF HUMAN DECR. HOMO SAPIENS SHORT CHAIN DEHYDROGENASE REDUCTASE SELENOMETHIONINE SAD DIENOYL-COA OXIDOREDUCTASE
Ref.: STRUCTURE AND REACTIVITY OF HUMAN MITOCHONDRIAL 2,4-DIENOYL-COA REDUCTASE: ENZYME-LIGAND INTERACTIONS IN A DISTINCTIVE SHORT-CHAIN REDUCTASE ACTIVE SITE J.BIOL.CHEM. V. 280 3068 2005
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 5 families.
1 1W8D - NAP C21 H28 N7 O17 P3 c1cc(c[n+]....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 5 families.
1 1W8D - NAP C21 H28 N7 O17 P3 c1cc(c[n+]....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 5 families.
1 1W8D - NAP C21 H28 N7 O17 P3 c1cc(c[n+]....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: NAP; Similar ligands found: 123
No: Ligand ECFP6 Tc MDL keys Tc
1 NAP 1 1
2 NA0 0.881356 0.986301
3 TAP 0.872881 0.934211
4 NDO 0.840336 0.972603
5 NAD 0.811966 0.986111
6 N01 0.733871 0.958904
7 A3D 0.712 0.972603
8 NBP 0.707692 0.935065
9 NHD 0.68254 0.958904
10 NJP 0.661417 0.972973
11 NFD 0.658915 0.934211
12 NXX 0.619048 0.959459
13 DND 0.619048 0.959459
14 AMP NAD 0.606061 0.958904
15 ZID 0.605839 0.972603
16 NAQ 0.59854 0.922078
17 ATR 0.59292 0.917808
18 NAE 0.591241 0.946667
19 NDE 0.58042 0.986301
20 A22 0.571429 0.958904
21 NAJ 0.567164 0.986111
22 A2R 0.563025 0.932432
23 NDC 0.561644 0.922078
24 NA7 0.552846 0.907895
25 ODP 0.551471 0.935065
26 A2P 0.539823 0.930556
27 8ID 0.537313 0.910256
28 NPW 0.525547 0.8875
29 NZQ 0.521739 0.910256
30 CNA 0.521739 0.959459
31 NDP 0.514493 0.922078
32 PO4 PO4 A A A A PO4 0.503937 0.930556
33 1DG 0.503401 0.922078
34 DG1 0.503401 0.922078
35 TXP 0.5 0.922078
36 NMN AMP PO4 0.492958 0.921053
37 XNP 0.492958 0.875
38 25L 0.492308 0.958904
39 25A 0.492063 0.972222
40 NMN 0.486726 0.888889
41 NGD 0.485714 0.935065
42 9JJ 0.481707 0.8875
43 2AM 0.477876 0.891892
44 ADP 0.458333 0.945205
45 PAP 0.451613 0.931507
46 A2D 0.445378 0.945205
47 AN2 0.442623 0.932432
48 7L1 0.441558 0.777778
49 ADP PO3 0.44 0.944444
50 SAP 0.44 0.896104
51 AGS 0.44 0.896104
52 M33 0.439024 0.906667
53 AR6 AR6 0.438849 0.945205
54 BA3 0.438017 0.945205
55 OAD 0.43609 0.92
56 ADP BMA 0.43609 0.92
57 DQV 0.435714 0.958904
58 HEJ 0.435484 0.945205
59 ATP 0.435484 0.945205
60 OOB 0.435115 0.958904
61 B4P 0.434426 0.945205
62 AP5 0.434426 0.945205
63 GAP 0.433071 0.92
64 0WD 0.432432 0.922078
65 2A5 0.432 0.87013
66 5FA 0.432 0.945205
67 AQP 0.432 0.945205
68 AT4 0.430894 0.907895
69 00A 0.428571 0.909091
70 DAL AMP 0.427481 0.932432
71 CA0 0.427419 0.92
72 ADP ALF 0.426357 0.871795
73 ALF ADP 0.426357 0.871795
74 9X8 0.425373 0.871795
75 ACP 0.424 0.92
76 NAJ PZO 0.423841 0.897436
77 9SN 0.423358 0.897436
78 ADP VO4 0.423077 0.932432
79 VO4 ADP 0.423077 0.932432
80 WAQ 0.422222 0.884615
81 V3L 0.421875 0.945205
82 ACQ 0.421875 0.92
83 ADQ 0.421053 0.92
84 AR6 0.420635 0.918919
85 APR 0.420635 0.918919
86 ATP A A A 0.42029 0.958333
87 CO7 0.419753 0.786517
88 3OD 0.419118 0.92
89 1ZZ 0.419118 0.841463
90 DLL 0.41791 0.958904
91 AD9 0.417323 0.92
92 NAX 0.416667 0.875
93 OVE 0.416667 0.857143
94 MYR AMP 0.416058 0.841463
95 AV2 0.415385 0.868421
96 A3P 0.414634 0.944444
97 NNR 0.414414 0.72973
98 OMR 0.413793 0.831325
99 6YZ 0.412214 0.92
100 ANP 0.410853 0.92
101 A1R 0.410448 0.860759
102 ABM 0.409836 0.893333
103 A 0.408333 0.944444
104 AMP 0.408333 0.944444
105 SON 0.408 0.933333
106 PPS 0.407692 0.829268
107 5AL 0.407692 0.932432
108 NAI 0.406897 0.909091
109 7D3 0.406504 0.857143
110 ADX 0.404762 0.829268
111 ATF 0.40458 0.907895
112 3UK 0.404412 0.945946
113 TYR AMP 0.404255 0.921053
114 AMP DBH 0.404255 0.894737
115 139 0.402685 0.875
116 50T 0.401575 0.906667
117 SRP 0.401515 0.907895
118 A A 0.40146 0.972222
119 B5V 0.40146 0.933333
120 A3R 0.4 0.860759
121 3AM 0.4 0.90411
122 B5M 0.4 0.921053
123 FA5 0.4 0.933333
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1W8D; Ligand: NAP; Similar sites found with APoc: 944
This union binding pocket(no: 1) in the query (biounit: 1w8d.bio1) has 26 residues
No: Leader PDB Ligand Sequence Similarity
1 2UYQ SAM None
2 1VKO NAD 0.993378
3 6ECU SAH 0.993378
4 1UP7 NAD 0.993378
5 6ECW SAH 0.993378
6 5XLX SAH 1.06383
7 1R18 SAH 1.32159
8 3WMX NAD 1.3245
9 4GKV NAD 1.3245
10 2EXX NAP 1.3245
11 1PZG A3D 1.3245
12 1I2B UPG 1.3245
13 1I2B USQ 1.3245
14 1I2B NAD 1.3245
15 5W7M SAH 1.3245
16 5YAP NAI 1.3245
17 5YAP 8S0 1.3245
18 1E7S NAP 1.65563
19 4XQC 13D 1.65563
20 4XQC NAD 1.65563
21 2FZW NAD 1.65563
22 1R6D DAU 1.65563
23 1R6D NAD 1.65563
24 1O6Z NAD 1.65563
25 1KOL NAD 1.65563
26 5EOW FAD 1.65563
27 4AP3 NAP 1.65563
28 4AP3 FAD 1.65563
29 5JAQ NAI 1.65563
30 2WET FAD 1.65563
31 1CF2 NAP 1.65563
32 1X7D ORN 1.65563
33 1X7D NAD 1.65563
34 6F97 FAD 1.65563
35 2CUL FAD 1.72414
36 1ZQ9 SAM 1.75439
37 5YJF 8WO 1.76056
38 5YJF SAH 1.76056
39 2G5C NAD 1.77936
40 6EQS BV8 1.81818
41 3A27 SAM 1.83824
42 1OC2 NAD 1.98676
43 1OC2 TDX 1.98676
44 1N7G GDR 1.98676
45 4PVD NDP 1.98676
46 2C29 NAP 1.98676
47 5AOV NAP 1.98676
48 2C29 DQH 1.98676
49 3WLE NAD 1.98676
50 5XVH NAP 1.98676
51 5X68 FAD 1.98676
52 3FSY SCA 1.98676
53 3AYI FAD 1.98676
54 3AYI HCI 1.98676
55 4DSG UDP 1.98676
56 4DSG FAD 1.98676
57 3L9W AMP 1.98676
58 2XVF FAD 1.98676
59 4X9M FAD 1.98676
60 4D04 NAP 1.98676
61 4D04 FAD 1.98676
62 4JDR FAD 1.98676
63 5W7K SAH 1.98676
64 5DOZ NDP 1.98676
65 4EDF UPG 1.98676
66 3FPZ AHZ 1.98676
67 1COY FAD 1.98676
68 4R5M NAP 1.98676
69 4R5M 4NO 1.98676
70 1N7G NDP 1.98676
71 5ERG SAM 1.98676
72 1GZ4 ATP 1.99637
73 5OJL TXP 2.01342
74 5EES NAP 2.02429
75 1H6C NDP 2.07852
76 1H6C SIN 2.07852
77 1NPD NAD 2.08333
78 1NVT NAP 2.09059
79 1RP0 AHZ 2.11268
80 5BSH PRO 2.16606
81 3WV8 ATP 2.29358
82 4U7W NDP 2.31788
83 1ORR NAD 2.31788
84 4J36 1HR 2.31788
85 4J36 FAD 2.31788
86 2CDU ADP 2.31788
87 2CDU FAD 2.31788
88 1U3U BNF 2.31788
89 1U3U NAD 2.31788
90 2E5V FAD 2.31788
91 3WGT QSC 2.31788
92 3WGT FAD 2.31788
93 5H81 NAP 2.31788
94 3HDY FAD 2.31788
95 1U1I NAD 2.31788
96 3HDY FDA 2.31788
97 3HDY GDU 2.31788
98 1ZK7 FAD 2.31788
99 5LD5 NAD 2.31788
100 5M67 3D1 2.31788
101 5M67 NAD 2.31788
102 5M67 ADE 2.31788
103 5GSN NAP 2.31788
104 5GSN FAD 2.31788
105 4YUW 4JU 2.31788
106 4YUW S4M 2.31788
107 1HKU NAD 2.31788
108 2CVQ NDP 2.31788
109 1OMO NAD 2.31788
110 2DM6 NAP 2.31788
111 1FP1 SAH 2.31788
112 5GSN MMZ 2.31788
113 5KOK SAH 2.31788
114 4IDC NDP 2.31788
115 4IDC 1XX 2.31788
116 5KVS NAP 2.31788
117 1U8X NAD 2.31788
118 2DM6 IMN 2.31788
119 2EG5 SAH 2.31788
120 3VSE SAH 2.31788
121 5WGR FAD 2.31788
122 2PXX SAH 2.32558
123 3ELW SAM 2.33333
124 3ELW GP3 2.33333
125 3MB5 SAM 2.35294
126 5OCM NAP 2.4055
127 1WP4 NDP 2.42215
128 2OBF F83 2.42215
129 2OBF SAH 2.42215
130 2CVZ NDP 2.42215
131 3GU3 SAH 2.46479
132 2RGJ FAD 2.48756
133 5GVR LMR 2.5641
134 4R1S NAP 2.64901
135 3LU1 NAD 2.64901
136 4PIV NDP 2.64901
137 1EQ2 NAP 2.64901
138 2X6T NAP 2.64901
139 1GV0 NAD 2.64901
140 1SB8 NAD 2.64901
141 1WDK NAD 2.64901
142 2PZM UDP 2.64901
143 2PZM NAD 2.64901
144 1SB8 UD2 2.64901
145 3CMC NAD 2.64901
146 1R37 NAD 2.64901
147 3G5S FAD 2.64901
148 5UAO FAD 2.64901
149 5NUF NAD 2.64901
150 3NTA FAD 2.64901
151 1D4D FAD 2.64901
152 2VTD LKM 2.64901
153 3H9E NAD 2.64901
154 4M52 FAD 2.64901
155 5NUE NAD 2.64901
156 4C3Y FAD 2.64901
157 3NT6 FAD 2.64901
158 3NTD FAD 2.64901
159 4C3Y ANB 2.64901
160 2WPF FAD 2.64901
161 2WPF WPF 2.64901
162 3O9Z NAD 2.64901
163 3O9Z AKG 2.64901
164 1J5P NAD 2.64901
165 1HYE NAP 2.64901
166 3X0D SAH 2.64901
167 3OZ2 FAD 2.64901
168 6FP4 E1T 2.64901
169 1YQD NAP 2.64901
170 5HXI FAD 2.64901
171 5HXI 5HN 2.64901
172 5J7X FAD 2.64901
173 1KJ8 GAR 2.64901
174 6FP4 FAD 2.64901
175 4USQ FAD 2.64901
176 1N1G BCP 2.64901
177 1I8T FAD 2.7248
178 5OCQ CIT 2.80702
179 1KYQ NAD 2.91971
180 5T9F TYR 2.95203
181 5T9F NAP 2.95203
182 5T9E NAP 2.95203
183 1XCL SAH 2.97872
184 4GLL NAD 2.98013
185 5MSO NAP 2.98013
186 1GY8 NAD 2.98013
187 1A5Z NAD 2.98013
188 1H9A NAP 2.98013
189 4MDH NAD 2.98013
190 4L8V NAP 2.98013
191 5MDH NAD 2.98013
192 1PJS NAD 2.98013
193 2ZJ1 ARJ 2.98013
194 2ZJ1 NAD 2.98013
195 3V1Y NAD 2.98013
196 1J49 NAD 2.98013
197 3SSO SAH 2.98013
198 1YQZ FAD 2.98013
199 1YJQ NAP 2.98013
200 3LKZ SFG 2.98013
201 5DNK SAH 2.98013
202 5MPT SAH 2.98013
203 1CDO NAD 2.98013
204 6C4T NA7 2.98013
205 2C7G FAD 2.98013
206 2C7G ODP 2.98013
207 5Z21 NAI 2.98013
208 1EBF NAD 2.98013
209 5J5Z FAD 2.98013
210 2B4R NAD 2.98013
211 1ZGA SAH 2.98013
212 4IV9 FAD 2.98013
213 6F3M NAD 2.98013
214 4Z0H NAD 2.98013
215 6F3N ADN 2.98013
216 6F3N NAD 2.98013
217 2GCG NDP 2.98013
218 2B4R AES 2.98013
219 3NYC FAD 2.98013
220 3NYC IAR 2.98013
221 3GMB FAD 2.98013
222 4B2D SER 2.98013
223 5GM1 SAH 2.98013
224 4XB2 NDP 2.98507
225 4XB2 HSE 2.98507
226 2VN9 GVD 2.99003
227 3CIF G3H 3.06407
228 3CIF NAD 3.06407
229 5F5N NAD 3.11419
230 1PN0 FAD 3.15789
231 1PN0 IPH 3.15789
232 4MIG G3F 3.24074
233 2HK9 ATR 3.27273
234 2HK9 NAP 3.27273
235 4G5H UD7 3.31126
236 4G5H NAP 3.31126
237 1KEW NAD 3.31126
238 1KEW TYD 3.31126
239 3KO8 NAD 3.31126
240 6DNT NAD 3.31126
241 6EL3 NAP 3.31126
242 3GGO NAI 3.31126
243 3GGO ENO 3.31126
244 2Q1S NAI 3.31126
245 3ICT FAD 3.31126
246 3ICS ADP 3.31126
247 3ICS FAD 3.31126
248 3ICR FAD 3.31126
249 5A1T NAI 3.31126
250 3UCL NAP 3.31126
251 6BII NAP 3.31126
252 3AXB FAD 3.31126
253 3AXB PRO 3.31126
254 3UCL FAD 3.31126
255 3UCL CYH 3.31126
256 3ICT ADP 3.31126
257 3T31 DCQ 3.31126
258 3T31 FAD 3.31126
259 5A1T OXM 3.31126
260 5G3U FDA 3.31126
261 2QA1 FAD 3.31126
262 6FDF SAH 3.31126
263 3L4S NAD 3.31126
264 3L4S 3PG 3.31126
265 2VVL FAD 3.31126
266 4LWP SAH 3.31126
267 4E5N NAD 3.31126
268 5KMS FAD 3.31126
269 5TC4 NAD 3.31126
270 2JHP SAH 3.31126
271 1DJN ADP 3.31126
272 1Y8Q ATP 3.31126
273 4DPL NAP 3.31126
274 5G3U ITW 3.31126
275 3WBF API 3.31126
276 5KMS NAD 3.31126
277 3E1T FAD 3.31126
278 5TTJ FAD 3.31126
279 1YKJ PHB 3.31126
280 1YKJ FAD 3.31126
281 3OJO NAD 3.31126
282 5WP5 SAH 3.31126
283 2YX1 SFG 3.31126
284 4KIB SAH 3.31126
285 5I39 FAD 3.31126
286 4D7E FAD 3.31126
287 3WBF NAP 3.31126
288 2PV7 NAD 3.3557
289 5U5G NAP 3.38983
290 4YCA NDP 3.40136
291 3LCC SAH 3.40426
292 2EV9 SKM 3.42205
293 2EV9 NAP 3.42205
294 5FJN FAD 3.50877
295 5FJN BE2 3.50877
296 4EA7 JB2 3.63636
297 4EA7 COA 3.63636
298 1BXK NAD 3.64238
299 4HXY NDP 3.64238
300 1LTH NAD 3.64238
301 3CGB FAD 3.64238
302 3CGD FAD 3.64238
303 3CGD NAD 3.64238
304 3CGD COA 3.64238
305 5X9D 80F 3.64238
306 6AA8 NAD 3.64238
307 5Y77 FAD 3.64238
308 5MZI FYK 3.64238
309 5MZI FAD 3.64238
310 4MO2 FDA 3.64238
311 4MO2 FAD 3.64238
312 1J0X NAD 3.64238
313 4OPC FDA 3.64238
314 4OPC PGT 3.64238
315 2VVM FAD 3.64238
316 1GR0 NAD 3.64238
317 1FP2 SAH 3.64238
318 4ARU TLA 3.64238
319 4C4A SAH 3.64238
320 3KLJ FAD 3.64238
321 4KOA NDP 3.64238
322 3OA2 NAD 3.64238
323 1GPE FAD 3.64238
324 1P77 ATR 3.67647
325 4YMH SAH 3.75
326 1I36 NAP 3.78788
327 2DC1 NAD 3.81356
328 2PWY SAH 3.87597
329 4E13 NAD 3.88693
330 4EUE NAI 3.97351
331 3VPH NAD 3.97351
332 1UWK URO 3.97351
333 1UWK NAD 3.97351
334 1E5Q NDP 3.97351
335 3VPH OXM 3.97351
336 1T26 NAI 3.97351
337 1T26 GBD 3.97351
338 4LHD GLY 3.97351
339 1P0F NAP 3.97351
340 3TWO NDP 3.97351
341 4MOP 2H5 3.97351
342 5ZYN FAD 3.97351
343 1XHC FAD 3.97351
344 1LDN NAD 3.97351
345 3CTY FAD 3.97351
346 6AIN FAD 3.97351
347 1QO8 FAD 3.97351
348 2JB2 FAD 3.97351
349 2JB2 PHE 3.97351
350 1SOW NAD 3.97351
351 2AQJ FAD 3.97351
352 2AQJ TRP 3.97351
353 5E8J SAH 3.97351
354 2RAB FAD 3.97351
355 1DSS NAD 3.97351
356 4CNK FAD 3.97351
357 2RAB NAD 3.97351
358 5E9W SAH 3.97351
359 4AT0 FAD 3.97351
360 3G89 SAM 4.01606
361 2VDV SAM 4.06504
362 1C3V NDP 4.08163
363 3T7S SAM 4.10448
364 4ZRN NAD 4.16667
365 4ZRN UPG 4.16667
366 1UXG NAD 4.20712
367 1UXG FUM 4.20712
368 4RQU NAD 4.26667
369 2F1K NAP 4.30108
370 5L4L NAP 4.30464
371 2GZ3 NAP 4.30464
372 1SAY PYR 4.30464
373 5L4L 7OX 4.30464
374 5JJR SAH 4.30464
375 1VQW FAD 4.30464
376 2GV8 FAD 4.30464
377 3B1J NAD 4.30464
378 2GVC FAD 4.30464
379 1C1X NAD 4.30464
380 1BW9 NAD 4.30464
381 2A92 NAI 4.30464
382 5HSA FAS 4.30464
383 5BVA FAD 4.30464
384 4MP8 NAD 4.30464
385 4MP8 MLI 4.30464
386 1YB5 NAP 4.30464
387 3B20 NAD 4.30464
388 5N0J FAD 4.30464
389 4DMG SAM 4.30464
390 5AYV NAP 4.30464
391 1BXG NAD 4.30464
392 5AHO TLA 4.30464
393 3A06 FOM 4.30464
394 5ZZ6 ADP 4.32692
395 5ZZ6 NAD 4.32692
396 5N6C NAD 4.33333
397 1D4O NAP 4.34783
398 2P3I MNA 4.34783
399 3QX9 ATP 4.34783
400 1VM6 NAD 4.38596
401 1PNO NAP 4.44444
402 4RDH AMP 4.51389
403 4RDI ATP 4.51389
404 6GAR FAD 4.58453
405 3A4V PYR 4.63576
406 3A4V NAD 4.63576
407 3I6I NDP 4.63576
408 3ABI NAD 4.63576
409 1H2B NAJ 4.63576
410 5BJX NAD 4.63576
411 1EZ4 NAD 4.63576
412 5BJX UDP 4.63576
413 1LLU NAD 4.63576
414 2C5A GDC 4.63576
415 2C5A NAD 4.63576
416 1X87 NAD 4.63576
417 2Y6Q I7T 4.63576
418 5UR0 NAD 4.63576
419 4D3F NAP 4.63576
420 1UDB NAD 4.63576
421 1UDB UFG 4.63576
422 4TXI FAD 4.63576
423 3H8V ATP 4.63576
424 1V59 FAD 4.63576
425 2BRY FAD 4.63576
426 1YY5 FAD 4.63576
427 1RSG FAD 4.63576
428 5CAE SIN 4.63576
429 3H5N ATP 4.63576
430 1NVM NAD 4.63576
431 5CAE COA 4.63576
432 1V59 NAD 4.63576
433 4PNE SAH 4.63576
434 5JCM ISD 4.63576
435 5JCM NAD 4.63576
436 5JCM FAD 4.63576
437 3WQQ NDP 4.63576
438 3WQQ IB3 4.63576
439 2Y6Q FAD 4.63576
440 3X0V FAD 4.63576
441 5TS5 FAD 4.63576
442 5CDH TLA 4.63576
443 6A3J NAI 4.63576
444 4N49 SAM 4.63576
445 4D79 ATP 4.71014
446 1PL6 NAD 4.77528
447 1PL6 572 4.77528
448 3EGI ADP 4.85437
449 5CUQ NSC 4.86891
450 6DUB SAH 4.95496
451 2Q1W NAD 4.96689
452 5XNC MTA 4.96689
453 3GFB NAD 4.96689
454 4RPL 3UC 4.96689
455 4RPL FAD 4.96689
456 5ZI2 NAD 4.96689
457 5ZI2 ADP 4.96689
458 2P41 SAH 4.96689
459 5TOW NAI 4.96689
460 5TOW ADN 4.96689
461 2Z3Y F2N 4.96689
462 1DJL NAP 4.96689
463 4K5S FAD 4.96689
464 4K5S PM0 4.96689
465 1D1T NAD 4.96689
466 5K0A FAD 4.96689
467 1KEV NDP 4.96689
468 4UCI SAM 4.96689
469 3W9F I3P 5
470 2V6G NAP 5.29801
471 1RPN NDP 5.29801
472 1HYH NAD 5.29801
473 2VHW NAI 5.29801
474 3QJ4 FAD 5.29801
475 4ZCC NAI 5.29801
476 4ZCC FAD 5.29801
477 5OC1 FAD 5.29801
478 5NMX FAD 5.29801
479 5MW4 5JU 5.29801
480 5NMX NAP 5.29801
481 2GAG NAD 5.29801
482 5JE8 NAD 5.29801
483 3LST SAH 5.29801
484 5BRT FAD 5.29801
485 5BRT CH9 5.29801
486 1Q0H NDP 5.29801
487 1Q0H FOM 5.29801
488 2GAG FAD 5.29801
489 2GAG FOA 5.29801
490 4GUT FAD 5.29801
491 1BZL GCG 5.29801
492 4HSU FAD 5.29801
493 4GUS FAD 5.29801
494 4FWE FAD 5.29801
495 4CJX NAP 5.32915
496 1JNR FAD 5.33333
497 3EVG SAH 5.45455
498 2XVM SAH 5.52764
499 2JL1 NAP 5.57491
500 2VT3 ATP 5.5814
501 1E3I CXF 5.58511
502 4ZVV NAD 5.62914
503 4ZVV GN0 5.62914
504 5K4W NAI 5.62914
505 5K4W THR 5.62914
506 4PLG OXM 5.62914
507 4PLG NAI 5.62914
508 1GUZ NAD 5.62914
509 5YEC ATP 5.62914
510 9LDT NAD 5.62914
511 3HAD NAD 5.62914
512 3NJ4 AFX 5.62914
513 3NJ4 NAD 5.62914
514 9LDB NAD 5.62914
515 1LDM NAD 5.62914
516 3OND ADN 5.62914
517 3OND NAD 5.62914
518 3GF4 UPG 5.62914
519 3GF4 FAD 5.62914
520 1G55 SAH 5.62914
521 1GET NAP 5.62914
522 1GET FAD 5.62914
523 5JY6 NAD 5.62914
524 4TM3 FAD 5.62914
525 2QRK AMP 5.62914
526 1V8B NAD 5.62914
527 4IF4 BEF 5.76923
528 3BXO SAM 5.85774
529 5XWV NDP 5.96026
530 5XWV 8H6 5.96026
531 2HJR APR 5.96026
532 4RSL FAD 5.96026
533 1V6A TRE 5.96026
534 5TWB FAD 5.96026
535 5NA1 FAD 5.96026
536 1DLJ NAI 5.96026
537 1DLJ UGA 5.96026
538 5UAV TFB 5.96026
539 2I3G NAP 5.96026
540 5A04 NDP 5.96026
541 5A04 BGC 5.96026
542 1RYD NDP 5.96026
543 5UAV NDP 5.96026
544 1QPR PHT 5.96026
545 5TUF TDC 5.96026
546 5TUF FAD 5.96026
547 5ULP KB1 5.97015
548 3RFV NAI 5.99251
549 3RFV 15L 5.99251
550 5Z2F NAP 6.03774
551 2WA2 SAM 6.15942
552 2DT5 NAD 6.16114
553 4J4H NAI 6.17761
554 4J4H 1J1 6.17761
555 4JK3 NAD 6.17761
556 5ZEC NAP 6.29139
557 1C0I BE2 6.29139
558 1C0I FAD 6.29139
559 6ER9 NAP 6.29139
560 6ER9 FAD 6.29139
561 5JCA FAD 6.29139
562 5JCA NDP 6.29139
563 3KB6 NAD 6.29139
564 2GSD NAD 6.29139
565 2Q7V FAD 6.29139
566 4B63 NAP 6.29139
567 4B63 ORN 6.29139
568 4B63 FAD 6.29139
569 2IID PHE 6.29139
570 2IID FAD 6.29139
571 1GTE FAD 6.29139
572 4YSX FAD 6.38298
573 4ZGS NAD 6.62252
574 5JWC FAD 6.62252
575 6CEP NAD 6.62252
576 6CEP OXM 6.62252
577 2OOR NAD 6.62252
578 4OM8 NAD 6.62252
579 2ZXI FAD 6.62252
580 3ZNN FAD 6.62252
581 3ZNN 4WL 6.62252
582 3UOY NAP 6.62252
583 3UOY FAD 6.62252
584 1O94 ADP 6.62252
585 1NM5 NAP 6.62252
586 1NM5 NAD 6.62252
587 4REP FAD 6.62252
588 1F8G NAD 6.62252
589 2Q0L NAP 6.62252
590 2OOR TXP 6.62252
591 2Q0L FAD 6.62252
592 1LVL NAD 6.62252
593 3O7W SAM 6.80272
594 5DF1 58X 6.95364
595 5DF1 NAP 6.95364
596 3BAZ NAP 6.95364
597 5MIT NAP 6.95364
598 5MIT FAD 6.95364
599 5VN0 FAD 6.95364
600 3GCZ SAM 6.95364
601 6GAS FAD 6.95364
602 2NAD NAD 6.95364
603 5VN0 NAI 6.95364
604 2NU8 COA 6.95364
605 1HDR NAD 6.96721
606 3RJ5 NAD 7.08661
607 1LSS NAD 7.14286
608 5U5N NAD 7.16846
609 4NEC SAH 7.19697
610 1EJ0 SAM 7.22222
611 3B1F NAD 7.24138
612 1Y1P NMN AMP PO4 7.28477
613 4FZV SAM 7.28477
614 2DFV NAD 7.28477
615 2QZZ NAP 7.28477
616 2QZZ EMF 7.28477
617 1SQF SAM 7.28477
618 5U8U FAD 7.28477
619 2O4C NAD 7.28477
620 4EMI NAD 7.28477
621 4EMI FAD 7.28477
622 3C1O NAP 7.28477
623 1REO FAD 7.28477
624 3A4T SFG 7.29927
625 6A56 LAT 7.31707
626 5L95 AMP 7.5
627 3BP1 GUN 7.58621
628 5TVI O8N 7.6087
629 2JHF NAD 7.61589
630 4EIP FAD 7.61589
631 3LAD FAD 7.61589
632 2DKH FAD 7.94702
633 4XYB NDP 7.94702
634 2DKH 3HB 7.94702
635 1NYT NAP 7.94702
636 3IHG FAD 8.2243
637 4OOE FOM 8.27815
638 4OOE NDP 8.27815
639 1KYZ SAH 8.27815
640 2VYN NAD 8.27815
641 3QV1 NAD 8.27815
642 1MV8 NAD 8.27815
643 4YRY FAD 8.27815
644 4YRY NAD 8.27815
645 1CER NAD 8.27815
646 1GAD NAD 8.27815
647 4M37 SAH 8.27815
648 1MUU NAD 8.27815
649 2PX8 SAH 8.27815
650 4M38 SAH 8.27815
651 3FGZ BEF 8.59375
652 5Y1G NAD 8.60927
653 5Y1G AKB 8.60927
654 5DN9 NAD 8.60927
655 2XVE FAD 8.60927
656 1GQ2 NAP 8.60927
657 3GD4 FAD 8.60927
658 3GD4 NAD 8.60927
659 4BV6 FAD 8.60927
660 1E1M NAP 8.69565
661 1E1M FAD 8.69565
662 1E6E FAD 8.69565
663 5Y8L NAD 8.81356
664 5Y8L HUI 8.81356
665 4QTU SAM 8.88889
666 2GN4 UD1 8.9404
667 2GN4 NDP 8.9404
668 2YY7 NAD 8.9404
669 1B8U NAD 8.9404
670 1B8U OAA 8.9404
671 5YU3 NAD 8.9404
672 5YU3 PRO 8.9404
673 1F8F NAD 8.9404
674 4XZ3 COA 9.13043
675 3AB1 FAD 9.16667
676 1Z45 NAD 9.27152
677 5KKA 6V0 9.27152
678 4W6Z 8ID 9.27152
679 2IZ1 ATR 9.27152
680 5Z75 NAD 9.60265
681 1H82 GZZ 9.60265
682 1H82 FAD 9.60265
683 5Z20 NAI 9.60265
684 2B5W NAP 9.93377
685 5O9F NAD 9.93377
686 5O9F 9ON 9.93377
687 2BMB PMM 9.93377
688 5WP4 SAH 9.93377
689 4POO SAM 10
690 2PK3 A2R 10.2649
691 3S5W FAD 10.2649
692 2Q46 NAP 10.2767
693 3AD8 NAD 10.3448
694 3AD8 FAD 10.3448
695 3AD8 PYC 10.3448
696 3HVJ 705 10.4072
697 1RM0 D6P 10.596
698 1RM0 NAI 10.596
699 1HDG NAD 10.596
700 1RM4 NDP 10.596
701 5BW4 SAM 10.596
702 1VL0 NAI 10.6164
703 1G60 SAM 10.7692
704 1SC6 NAD 10.9272
705 4U8P FDA 10.9272
706 4U8P UDP 10.9272
707 4II2 ATP 11.0429
708 5MLR GRQ 11.2583
709 5MLR NAP 11.2583
710 5KOX FAD 11.2583
711 5KOX RFP 11.2583
712 1EK6 NAI 11.5894
713 5IN4 6CK 11.5894
714 5IN4 GDP 11.5894
715 1EK6 UPG 11.5894
716 5IN4 NAP 11.5894
717 6A0S HSE 11.9205
718 6A0S NDP 11.9205
719 5GT9 NAP 12.2517
720 5O98 NAP 12.5828
721 3G2O SAM 12.5828
722 5FII PHE 12.7451
723 5L4S NAP 12.9139
724 5L4S 6KX 12.9139
725 3LZW FAD 13.5762
726 3LZW NAP 13.5762
727 1I9G SAM 13.5762
728 1N5D NDP 13.8889
729 4K26 NDP 14.1304
730 4K26 SFF 14.1304
731 2YRX AMP 14.2384
732 4J7U YTZ 14.5695
733 4J7U NAP 14.5695
734 3O26 NDP 14.9007
735 5L53 NAP 14.9007
736 1WVG APR 14.9007
737 1OAA OAA 14.9007
738 5J60 FAD 14.9007
739 2DBZ NAP 14.9701
740 2FR1 NDP 15.2318
741 3RNM FAD 15.5172
742 3ORF NAD 15.5378
743 1Z6Z NAP 15.5629
744 2IXB A2G 15.5629
745 2IXB NAD 15.5629
746 1V35 NAI 15.894
747 4OHU NAD 15.917
748 4OHU 2TK 15.917
749 2BOS GLA GAL GLC 16.1765
750 2BOS GLA GAL 16.1765
751 1RKX NAD 16.2252
752 5FA5 MTA 16.2252
753 4X60 3XV 16.2252
754 5I7S NAD 16.6667
755 5I7S E9P 16.6667
756 3WXB NDP 16.8874
757 2BKA NDP 16.9421
758 2HMT NAI 17.3611
759 5OOH 9ZZ 17.4757
760 5OOH NAP 17.4757
761 2NPX FAD 18.543
762 2NPX NAD 18.543
763 4M1U A2G MBG 18.5714
764 3OJF NDP 18.677
765 3OJF IMJ 18.677
766 1WMA AB3 19.2029
767 1WMA NDP 19.2029
768 2DKN NAI 19.2157
769 1FK8 NAD 19.8444
770 2CDC XYP 20.1987
771 2CDC NAP 20.1987
772 2CDC XYS 20.1987
773 4PLT NAI 20.1987
774 4PLT OXM 20.1987
775 2F5Z FAD 20.3125
776 6BWL NAD 21.5232
777 1D7O TCL 22.2222
778 1D7O NAD 22.2222
779 3OIG NAD 22.5564
780 1GZ6 NAI 23.1975
781 5EIN NAP 24.0741
782 1WUW TSU 24.4444
783 3CH6 NAP 24.4755
784 3CH6 311 24.4755
785 1ZBQ NAD 24.8344
786 4J1Q NDP 25.1656
787 1XSE NDP 25.4237
788 2AG5 NAD 26.0163
789 2BD0 NAP 26.2295
790 1A27 NAP 26.4901
791 3HB5 NAP 26.4901
792 4ITU NAI 27.1375
793 4ITU 1HS 27.1375
794 2GDZ NAD 27.4834
795 4YAG NAI 27.8146
796 4O1M NAD 27.8146
797 1NNU NAD 28.3333
798 1NNU TCT 28.3333
799 4YAC NAI 28.4768
800 4EMJ FAD 28.972
801 1JA9 NDP 29.927
802 4TQG NDP 30.1325
803 4Y9D NAI 30.1325
804 1XG5 NAP 30.466
805 1SNY NAP 31.7881
806 4OSP NAP 32.1192
807 4KWI 1TJ 32.4503
808 4KWI NAP 32.4503
809 3TN7 NJP 33.0739
810 3AFN NAP 33.1126
811 5WQP NAP 33.3333
812 5WQP NCA 33.3333
813 4D42 W0I 33.3333
814 4D42 NAP 33.3333
815 1MXH DHF 34.4371
816 1MXH NAP 34.4371
817 5GWT SIN 34.5324
818 5GWT NAD 34.5324
819 5O42 BGC 34.6715
820 5O42 NAD 34.6715
821 5O42 9JW 34.6715
822 5G4L NDP 34.965
823 1BDB NAD 35.0181
824 3A28 NAD 35.0993
825 1PR9 NAP 35.0993
826 3D3W NAP 35.0993
827 3U4C NDP 35.0993
828 3H4V DVP 35.0993
829 3H4V NAP 35.0993
830 3GEG NAD 35.4305
831 3VZS NAP 35.4305
832 3VZS CAA 35.4305
833 3ZV6 4HB 35.5872
834 3ZV6 NAD 35.5872
835 2PD4 NAD 35.6364
836 2PD4 DCN 35.6364
837 1ZEM NAD 35.7616
838 5YSS NAD 35.7616
839 2Q2V NAD 35.7616
840 1G0N PHH 36.4238
841 1G0N NDP 36.4238
842 5B4T 3HR 36.4238
843 5B4T NAD 36.4238
844 3ICC NAP 36.4238
845 3SJU NDP 36.755
846 4FN4 NAD 36.755
847 4NBW NAD 37.0861
848 2VZ0 NAP 37.0861
849 2VZ0 D64 37.0861
850 1E3W NAD 37.1647
851 1E6W NAD 37.3077
852 3RKR NAP 37.4046
853 4NBU NAI 37.4172
854 5EJ2 NAD 37.4172
855 2DTX BMA 37.4172
856 1GEG NAD 37.5
857 1H5Q NAP 37.7358
858 4CM9 NAP 37.7483
859 4CLR NAP 37.7483
860 2WD7 NAP 37.7483
861 3BMN NAP 37.7483
862 3JQ9 NAP 37.7483
863 4CM4 NAP 37.7483
864 3JQA NAP 37.7483
865 3JQG NAP 37.7483
866 3JQ7 NAP 37.7483
867 4CLO NAP 37.7483
868 4CME NAP 37.7483
869 3JQB NAP 37.7483
870 3JQ8 NAP 37.7483
871 3BMO NAP 37.7483
872 3BMQ NAP 37.7483
873 5JDC NAP 37.7483
874 3JQF NAP 37.7483
875 5JCJ NAP 37.7483
876 5JDI NAP 37.7483
877 4CMI NAP 37.7483
878 4CM8 NAP 37.7483
879 5K6A NAP 37.7483
880 2WYV NAD 37.7483
881 5JDI 6JO 37.7483
882 1U7T TDT 37.931
883 1U7T NAD 37.931
884 2CFC NAD 38
885 2AE2 NAP 38.0769
886 2AE2 PTO 38.0769
887 4NBT NAD 38.0795
888 2RH4 EMO 38.0795
889 5OVK NDP 38.4106
890 5OVL NAP 38.4106
891 2EWM NAD 38.4106
892 2JAH NDP 38.4615
893 2BGM NAJ 38.4892
894 1EDO NAP 38.5246
895 1UZN NAP 38.8664
896 3SJ7 NDP 38.8889
897 5Z2L NDP 39.1837
898 4RF2 NAP 39.3382
899 5WUW NAP 39.3728
900 1QG6 TCL 39.404
901 1QG6 NAD 39.404
902 2JAP NDP 39.6761
903 3V1U NAD 39.7351
904 4CQM NAP 39.7351
905 5FEU NAP 39.7351
906 5FFF 5XC 39.7351
907 5FFF NAP 39.7351
908 5CG1 NAD BBN 39.7351
909 3QWI NAP 40.3704
910 3QWI CUE 40.3704
911 2WSB NAD 40.5512
912 4Q9N NAI 40.604
913 2B4Q NAP 40.942
914 5T2U NAP 41.129
915 6F9Q NAD 41.1765
916 1AE1 NAP 41.3919
917 1XKQ NDP 41.7219
918 3OID NDP 41.8605
919 5OJI NAP 41.9231
920 5OJI ISN 41.9231
921 1XHL NDP 42.0875
922 1X1T NAD 42.3077
923 4QED NAP 42.3387
924 4O0L NDP 42.9091
925 1HDC CBO 42.9134
926 3O03 NAP 42.9553
927 1O5I NAD 42.9719
928 3AY6 NAI 43.1227
929 3AY6 BGC 43.1227
930 5THQ NDP 43.3824
931 1UAY ADN 44.2149
932 1ZK4 NAP 44.2231
933 1ZK4 AC0 44.2231
934 5EPO NAP 44.2748
935 2ZAT NAP 45
936 1NFQ NAI 45.3846
937 6CI9 NAP 45.5598
938 1YXM ADE 45.6954
939 1GEE NAD 46.3602
940 1IY8 NAD 46.8165
941 3NUG NAD 46.9636
942 4URF NAD 47.1774
943 4ZA2 NAD 48.2213
944 1VL8 NAP 49.0637
Pocket No.: 2; Query (leader) PDB : 1W8D; Ligand: NAP; Similar sites found with APoc: 41
This union binding pocket(no: 2) in the query (biounit: 1w8d.bio1) has 25 residues
No: Leader PDB Ligand Sequence Similarity
1 1COY AND 1.98676
2 3L9W GSH 1.98676
3 2AOT SAH 2.05479
4 5O4J PJL 2.18978
5 5O4J 9KH 2.18978
6 5O4J SAH 2.18978
7 2HUI GLV 2.31788
8 3GDN FAD 2.31788
9 3GDN HBX 2.31788
10 1TZD ADP 2.54545
11 3RUV ANP 2.64901
12 3FPF TNA 2.68456
13 3FPF MTA 2.68456
14 3RGG AIR 3.14465
15 4JLS 3ZE 3.28947
16 4M73 M72 3.31126
17 4M73 SAH 3.31126
18 3A06 NDP 4.30464
19 2D2I NAP 4.30464
20 1S7G APR 4.34783
21 6A3J SOE 4.63576
22 4KP7 1UQ 4.63576
23 4KP7 NAP 4.63576
24 1EFV FAD 5.09804
25 1EFV AMP 5.09804
26 6H8S FSZ 5.62914
27 2PT9 2MH 5.96026
28 1O97 AMP 6.62252
29 1O97 FAD 6.62252
30 1R27 MGD 6.95364
31 1SZD APR 7.40741
32 1Q9I TEO 8.27815
33 1Q9I FAD 8.27815
34 6BQ6 TER 9.93377
35 1KQR MNA 10.0559
36 4GQB 0XU 16.2252
37 4X60 SFG 16.2252
38 5C2N NAG 20.8333
39 3A25 SAM 23.9203
40 4CM9 YGL 37.7483
41 4CME KTZ 37.7483
Pocket No.: 3; Query (leader) PDB : 1W8D; Ligand: NAP; Similar sites found with APoc: 41
This union binding pocket(no: 3) in the query (biounit: 1w8d.bio1) has 26 residues
No: Leader PDB Ligand Sequence Similarity
1 5MBX FAD 1.65563
2 5MBX SP5 1.65563
3 1FEC FAD 2.31788
4 1I9Z 2IP 2.31788
5 2HQM FAD 2.31788
6 4WOH 4NP 2.40964
7 5JGL SAM 2.42215
8 1KNR FAD 2.64901
9 4YKG NAD 2.64901
10 3LXD FAD 2.64901
11 4YKG FAD 2.64901
12 5BUK FAD 2.98013
13 1MO9 FAD 3.31126
14 1MO9 KPC 3.31126
15 3Q9T FAY 3.31126
16 2YG3 FAD 3.31126
17 5A7Y SAH 3.64238
18 3QVP FAD 3.97351
19 1RJD SAM 3.97351
20 5ME4 HP4 4.37956
21 1TDF NAP 4.63576
22 1RJW ETF 4.96689
23 2NVK FAD 4.96689
24 3LQV ADE 5.21739
25 1BZL FAD 5.29801
26 1JLX GAL A2G MBN 5.29801
27 3NKS FAD 6.29139
28 4Z24 FAD 6.62252
29 4NTC FAD 6.62252
30 5EB4 FAD 7.28477
31 4JNA FAD 7.35294
32 3MQ2 SAH 7.79817
33 3K7M FAD 8.9404
34 5ZW3 SAH 9.60265
35 6D6Y SAH 10.2649
36 3PT9 SAH 12.2517
37 1Z0N BCD 13.5417
38 3KIF GDL 14.1509
39 2RIF AMP 18.4397
40 1Z42 FMN 18.543
41 3BMN AX3 37.7483
Pocket No.: 4; Query (leader) PDB : 1W8D; Ligand: NAP; Similar sites found with APoc: 36
This union binding pocket(no: 4) in the query (biounit: 1w8d.bio1) has 25 residues
No: Leader PDB Ligand Sequence Similarity
1 4RW3 TDA 1.3245
2 1TB4 PEJ 1.65563
3 5EW9 5VC 1.84502
4 4UP3 NDP 1.98676
5 1VI2 NAD 2
6 4XUC SAM 2.29358
7 4XUC 43G 2.29358
8 5THY SAH 2.31788
9 4AZW SAM 2.31788
10 1Z82 NDP 2.31788
11 5A89 ADP 2.5641
12 5A89 FMN 2.5641
13 5FI3 NAP 2.98013
14 5ZBC FAD 3.31126
15 5VKT NAP 3.8674
16 1ZDQ MSM 3.97351
17 5T2Y 753 4.0404
18 3VY6 BGC BGC 4.25532
19 5F8F SFG 4.30464
20 1YS4 NAP 4.63576
21