Receptor
PDB id Resolution Class Description Source Keywords
1WY7 2.2 Å EC: 2.1.1.- CRYSTAL STRUCTURE OF A PUTATIVE RNA METHYLTRANSFERASE PH1948 PYROCOCCUS HORIKOSHII PYROCOCCUS HORIKOSHII SEVEN-STRANDED BETA SHEET METHYLTRANSFERASE FOLD STRUCTURAGENOMICS TRANSFERASE
Ref.: CRYSTAL STRUCTURE OF THE PUTATIVE RNA METHYLTRANSFE PH1948 FROM PYROCOCCUS HORIKOSHII, IN COMPLEX WITH COPURIFIED S-ADENOSYL-L-HOMOCYSTEINE PROTEINS V. 61 1141 2005
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
SAH A:1001;
B:1002;
C:1003;
D:1004;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
submit data
384.411 C14 H20 N6 O5 S c1nc(...
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1WY7 2.2 Å EC: 2.1.1.- CRYSTAL STRUCTURE OF A PUTATIVE RNA METHYLTRANSFERASE PH1948 PYROCOCCUS HORIKOSHII PYROCOCCUS HORIKOSHII SEVEN-STRANDED BETA SHEET METHYLTRANSFERASE FOLD STRUCTURAGENOMICS TRANSFERASE
Ref.: CRYSTAL STRUCTURE OF THE PUTATIVE RNA METHYLTRANSFE PH1948 FROM PYROCOCCUS HORIKOSHII, IN COMPLEX WITH COPURIFIED S-ADENOSYL-L-HOMOCYSTEINE PROTEINS V. 61 1141 2005
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 57 families.
1 1WY7 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 50 families.
1 1WY7 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 44 families.
1 1WY7 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: SAH; Similar ligands found: 197
No: Ligand ECFP6 Tc MDL keys Tc
1 SAH 1 1
2 5X8 0.759494 0.969697
3 A7D 0.734177 0.926471
4 TT8 0.709302 0.970588
5 SXZ 0.692308 0.916667
6 DSH 0.692308 0.914286
7 DTA 0.666667 0.857143
8 3DH 0.662338 0.869565
9 S8M 0.655556 0.901408
10 SFG 0.635294 0.954545
11 SA8 0.62069 0.915493
12 EEM 0.617977 0.890411
13 MTA 0.615385 0.869565
14 SAI 0.613636 0.955882
15 S7M 0.586957 0.916667
16 36A 0.586538 0.90411
17 K15 0.583333 0.878378
18 RAB 0.573333 0.84058
19 ADN 0.573333 0.84058
20 XYA 0.573333 0.84058
21 62X 0.572917 0.855263
22 5CD 0.571429 0.852941
23 0UM 0.5625 0.876712
24 5N5 0.558442 0.84058
25 A4D 0.551282 0.867647
26 SAM 0.537634 0.916667
27 SSA 0.536842 0.712644
28 SMM 0.536842 0.88
29 KB1 0.534653 0.902778
30 A5D 0.532609 0.857143
31 SIB 0.53125 0.928571
32 EP4 0.530864 0.819444
33 DSZ 0.530612 0.732558
34 GSU 0.53 0.752941
35 AMP 0.529412 0.763158
36 A 0.529412 0.763158
37 5CA 0.525773 0.712644
38 ME8 0.524752 0.8125
39 M2T 0.52439 0.821918
40 6RE 0.523256 0.824324
41 GJV 0.522727 0.813333
42 AAT 0.515789 0.863014
43 LSS 0.515152 0.696629
44 KAA 0.514852 0.727273
45 J7C 0.511364 0.835616
46 A5A 0.510417 0.697674
47 SON 0.505495 0.805195
48 SRP 0.505155 0.805195
49 5AL 0.5 0.779221
50 VMS 0.5 0.681818
51 KH3 0.5 0.866667
52 ADX 0.5 0.694118
53 CA0 0.5 0.769231
54 AMP MG 0.5 0.74359
55 AMO 0.5 0.805195
56 54H 0.5 0.681818
57 AHX 0.49505 0.753086
58 TSB 0.494949 0.689655
59 53H 0.494949 0.674157
60 G5A 0.494737 0.712644
61 A2D 0.494382 0.74359
62 ABM 0.494382 0.74359
63 ZAS 0.494253 0.808219
64 A6D 0.490196 0.759494
65 8QN 0.49 0.779221
66 GEK 0.49 0.956522
67 GAP 0.489583 0.769231
68 A3S 0.48913 0.884058
69 AN2 0.48913 0.734177
70 S4M 0.488889 0.831169
71 SRA 0.488636 0.746835
72 LAD 0.485437 0.810127
73 52H 0.484848 0.674157
74 A12 0.483516 0.759494
75 BA3 0.483516 0.74359
76 AP2 0.483516 0.759494
77 AOC 0.483146 0.842857
78 NEC 0.483146 0.788732
79 Y3J 0.481481 0.768116
80 NVA LMS 0.480392 0.696629
81 VRT 0.479167 0.861111
82 50T 0.478723 0.734177
83 5AS 0.478261 0.655556
84 B4P 0.478261 0.74359
85 ADP 0.478261 0.74359
86 AP5 0.478261 0.74359
87 A3N 0.477778 0.830986
88 YSA 0.476636 0.712644
89 XAH 0.476636 0.768293
90 0XU 0.473684 0.897059
91 WAQ 0.471154 0.807692
92 NSS 0.470588 0.712644
93 5AD 0.468354 0.791045
94 ADP MG 0.468085 0.734177
95 AU1 0.468085 0.725
96 M33 0.468085 0.734177
97 MAO 0.467391 0.797468
98 TXA 0.466667 0.759494
99 A3G 0.466667 0.871429
100 NB8 0.466667 0.775
101 3AM 0.465909 0.727273
102 DAL AMP 0.465347 0.779221
103 ATP 0.463158 0.74359
104 ADP BEF 0.463158 0.716049
105 A3T 0.463158 0.842857
106 BEF ADP 0.463158 0.716049
107 ACP 0.463158 0.746835
108 7D7 0.4625 0.785714
109 LEU LMS 0.461538 0.677778
110 APC 0.458333 0.759494
111 AQP 0.458333 0.74359
112 APR 0.458333 0.766234
113 PRX 0.458333 0.746835
114 AR6 0.458333 0.766234
115 5FA 0.458333 0.74359
116 IOT 0.456897 0.761905
117 4AD 0.456311 0.794872
118 PAJ 0.456311 0.722892
119 WSA 0.45614 0.72093
120 FA5 0.453704 0.805195
121 YAP 0.453704 0.794872
122 RBY 0.453608 0.782051
123 ADV 0.453608 0.782051
124 ADP PO3 0.453608 0.763158
125 AD9 0.453608 0.725
126 SAP 0.453608 0.728395
127 AGS 0.453608 0.728395
128 PTJ 0.45283 0.731707
129 MHZ 0.452632 0.797468
130 00A 0.451923 0.740741
131 A3P 0.451613 0.74026
132 YLP 0.451327 0.771084
133 7MD 0.45045 0.768293
134 ALF ADP 0.45 0.707317
135 ADP ALF 0.45 0.707317
136 ATP MG 0.44898 0.734177
137 2VA 0.447917 0.819444
138 OOB 0.446602 0.779221
139 ANP 0.444444 0.725
140 ACQ 0.444444 0.746835
141 TAT 0.444444 0.7375
142 P5A 0.443396 0.719101
143 7D5 0.443182 0.708861
144 ARG AMP 0.442478 0.759036
145 A1R 0.442308 0.7625
146 YLC 0.439655 0.790123
147 2AM 0.438202 0.717949
148 DLL 0.438095 0.779221
149 A22 0.436893 0.734177
150 D3Y 0.436893 0.859155
151 TYR AMP 0.436364 0.782051
152 ATF 0.435644 0.716049
153 MYR AMP 0.435185 0.746988
154 SO8 0.434343 0.808219
155 3UK 0.433962 0.769231
156 OAD 0.433962 0.769231
157 TAD 0.433628 0.765432
158 25A 0.432692 0.74359
159 ANP MG 0.431373 0.707317
160 VO4 ADP 0.431373 0.734177
161 ADP VO4 0.431373 0.734177
162 9SN 0.431193 0.731707
163 TYM 0.431034 0.805195
164 PR8 0.429907 0.8
165 ADQ 0.428571 0.746835
166 YLB 0.42735 0.771084
167 3OD 0.425926 0.769231
168 FYA 0.425926 0.779221
169 1ZZ 0.425926 0.746988
170 PPS 0.425743 0.674419
171 NVA 2AD 0.424242 0.808219
172 MAP 0.423077 0.707317
173 A2P 0.421053 0.727273
174 4YB 0.421053 0.735632
175 ADP BMA 0.420561 0.746835
176 5SV 0.419048 0.731707
177 3NZ 0.416667 0.824324
178 YLA 0.416667 0.771084
179 48N 0.413793 0.753086
180 LPA AMP 0.413793 0.768293
181 AYB 0.413223 0.761905
182 QQY 0.413043 0.696203
183 ACK 0.413043 0.710526
184 JB6 0.412844 0.7625
185 BIS 0.412844 0.719512
186 PAP 0.41 0.730769
187 OVE 0.408602 0.7125
188 4UV 0.40708 0.75
189 AMP DBH 0.40708 0.746835
190 3AD 0.406977 0.852941
191 AF3 ADP 3PG 0.40678 0.743902
192 OMR 0.40678 0.738095
193 LAQ 0.405172 0.768293
194 A A 0.40367 0.74359
195 7C5 0.403509 0.789474
196 7MC 0.403361 0.75
197 4UU 0.4 0.75
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1WY7; Ligand: SAH; Similar sites found: 353
This union binding pocket(no: 1) in the query (biounit: 1wy7.bio3) has 24 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 5KVA SAM 0.0000007932 0.5583 None
2 3LN9 FLC 0.003196 0.44053 None
3 2FFQ GSP 0.007127 0.40047 None
4 5N5D SAM 0.00001747 0.49086 1.44928
5 1UAY ADN 0.003044 0.43332 1.44928
6 2CBZ ATP 0.01339 0.42834 1.44928
7 4U60 SIA 0.02231 0.40996 1.44928
8 3F81 STT 0.01723 0.40968 1.63934
9 3X1Z GNP 0.004793 0.40918 1.79641
10 3C3Y SAH 0.000001578 0.53261 1.93237
11 1Q0S SAH 0.000002519 0.51887 1.93237
12 4WZ6 ATP 0.03456 0.40116 1.93237
13 1G60 SAM 0.0000001654 0.60022 2.41546
14 5X62 SAH 0.00005487 0.50299 2.41546
15 3LRE ADP 0.01509 0.4247 2.41546
16 3A4M ADP 0.01887 0.41183 2.41546
17 1Q9I TEO 0.0183 0.41074 2.41546
18 1J71 THR ILE THR SER 0.02639 0.40566 2.41546
19 1JJV ATP 0.01288 0.42406 2.42718
20 4BQS ADP 0.01742 0.40523 2.84091
21 1ZC3 GNP 0.005298 0.40433 2.85714
22 3PT9 SAH 0.0000001621 0.5627 2.89855
23 3QOX SAH 0.000002216 0.54243 2.89855
24 5MW4 5JU 0.0003292 0.47626 2.89855
25 4PNE SAH 0.0002556 0.45719 2.89855
26 3RKR NAP 0.00257 0.44606 2.89855
27 2ODE ALF GDP 0.001591 0.43085 2.89855
28 3CV2 OXL 0.00714 0.42648 2.89855
29 1SVK ALF GDP 0.002713 0.42251 2.89855
30 1MO9 FAD 0.01764 0.42251 2.89855
31 5JGL SAM 0.000655 0.41917 2.89855
32 5JCM ISD 0.01545 0.41864 2.89855
33 5JCM FAD 0.01499 0.41864 2.89855
34 5JCM NAD 0.01545 0.41864 2.89855
35 1MO9 KPC 0.02192 0.41847 2.89855
36 2AOT SAH 0.0005803 0.41453 2.89855
37 4EUE NAI 0.005585 0.41306 2.89855
38 3AI3 SOL 0.01809 0.41278 2.89855
39 4KVG GTP 0.003485 0.4119 2.89855
40 2HXW FLC 0.02038 0.41009 2.89855
41 5T67 JHZ 0.0143 0.40817 2.89855
42 5T67 SAH 0.01244 0.40646 2.89855
43 2VVM FAD 0.01441 0.40362 2.89855
44 4MO2 FDA 0.01333 0.4022 2.89855
45 3H8V ATP 0.008535 0.40173 2.89855
46 3SBD GNP 0.002973 0.40208 3.20856
47 4P83 U5P 0.01349 0.4107 3.2967
48 3VYW SAM 0.0000008469 0.56337 3.38164
49 3HVJ 705 0.000006426 0.54743 3.38164
50 5THY SAH 0.000001873 0.53587 3.38164
51 5THZ SAH 0.000003735 0.53305 3.38164
52 2BZG SAH 0.00006916 0.49317 3.38164
53 4N49 SAM 0.00008362 0.47048 3.38164
54 1DQN IMU 0.001284 0.46631 3.38164
55 1XTP SAI 0.00005332 0.46431 3.38164
56 1V59 FAD 0.001827 0.44837 3.38164
57 5ITV NAI 0.001827 0.4326 3.38164
58 4RPL 3UC 0.01096 0.42686 3.38164
59 1REO FAD 0.004486 0.42509 3.38164
60 4RPL FAD 0.01136 0.42429 3.38164
61 3P2E SAH 0.001826 0.4236 3.38164
62 5JAQ NAI 0.005102 0.42262 3.38164
63 1PR9 NAP 0.005417 0.41485 3.38164
64 3D3W NAP 0.007561 0.40859 3.38164
65 1L1E SAH 0.004265 0.40813 3.38164
66 1W2D ADP 0.01555 0.40766 3.38164
67 3MJE NDP 0.006629 0.40603 3.38164
68 3DC4 ADP 0.02785 0.40302 3.38164
69 2NGR AF3 0.03023 0.40115 3.38164
70 2PWY SAH 0.0000002421 0.58217 3.48837
71 3FZG SAM 0.00419 0.42277 3.5
72 1F6B GDP 0.01783 0.40093 3.53535
73 3G2O SAM 0.00001465 0.52261 3.86473
74 4KRI SAH 0.00004916 0.48942 3.86473
75 3NUG NAD 0.001999 0.43092 3.86473
76 1TAD GDP 0.002201 0.4249 3.86473
77 1TAD ALF 0.002201 0.4249 3.86473
78 1QO8 FAD 0.00671 0.42028 3.86473
79 4AG5 ADP 0.01901 0.41508 3.86473
80 2RGO FAD 0.007796 0.41244 3.86473
81 5MBX FAD 0.01662 0.4113 3.86473
82 5MBX SP5 0.01662 0.4113 3.86473
83 2XVE FAD 0.02004 0.41087 3.86473
84 2R4J 13P 0.01698 0.40945 3.86473
85 3GDN HBX 0.01887 0.4066 3.86473
86 3GDN FAD 0.01357 0.4066 3.86473
87 1S7G NAD 0.01029 0.40041 3.86473
88 4BV6 FAD 0.01801 0.40022 3.86473
89 1G55 SAH 0.00000004578 0.62409 4.34783
90 3S1S SAH 0.00000002709 0.60631 4.34783
91 1DL5 SAH 0.0000004669 0.57765 4.34783
92 1JG3 ADN 0.00002693 0.51106 4.34783
93 4UCI SAM 0.00002479 0.48463 4.34783
94 4KIB SAH 0.00001289 0.48149 4.34783
95 1KYZ SAH 0.0003356 0.4632 4.34783
96 3TKY SAH 0.0002276 0.44759 4.34783
97 4A6D SAM 0.0006489 0.44647 4.34783
98 2C31 TZD 0.00814 0.43531 4.34783
99 2C31 ADP 0.007914 0.43531 4.34783
100 1BC5 SAH 0.000604 0.43413 4.34783
101 2OG2 MLI 0.008383 0.42641 4.34783
102 2IZ1 ATR 0.01572 0.41631 4.34783
103 4X9M FAD 0.008718 0.41332 4.34783
104 3GJB AKG 0.02224 0.40812 4.34783
105 5G3U FDA 0.01132 0.40633 4.34783
106 5G3U ITW 0.01511 0.40625 4.34783
107 1ELI PYC 0.012 0.40522 4.34783
108 1VG8 GNP 0.005822 0.40415 4.34783
109 1I8T FAD 0.01621 0.4004 4.34783
110 3IWD M2T 0.03836 0.40084 4.41176
111 3H2B SAH 0.0001214 0.47763 4.4335
112 1W7J ADP BEF 0.009424 0.40317 4.63576
113 2VUZ NAG BMA NAG MAN MAN NAG NAG 0.03202 0.40074 4.65116
114 3LKZ SFG 0.00000799 0.52817 4.83092
115 3JWH SAH 0.000002232 0.48599 4.83092
116 3BXO SAM 0.00001796 0.46145 4.83092
117 2AWN ADP 0.004854 0.45906 4.83092
118 3GXO SAH 0.002012 0.43733 4.83092
119 1X87 NAD 0.0008891 0.43481 4.83092
120 3U4C NDP 0.001511 0.43329 4.83092
121 1RSG FAD 0.004312 0.42883 4.83092
122 3BFV ADP 0.007633 0.42287 4.83092
123 1YY5 FAD 0.007095 0.42101 4.83092
124 2XTZ GSP 0.001167 0.41706 4.83092
125 2AE2 NAP 0.007707 0.41569 4.83092
126 2AE2 PTO 0.007707 0.41569 4.83092
127 5BW4 SAM 0.000779 0.41522 4.83092
128 4YAG NAI 0.009559 0.41341 4.83092
129 5GWX SAM 0.0006774 0.41186 4.83092
130 5GWX SAR 0.0006774 0.41186 4.83092
131 1AE1 NAP 0.006939 0.4102 4.83092
132 3GWZ SAH 0.0006833 0.40816 4.83092
133 2Q37 3AL 0.01077 0.42643 4.97238
134 4CVN ADP 0.02439 0.40602 5.10949
135 1R18 SAH 0.00000004535 0.60938 5.31401
136 5ULP KB1 0.0000008598 0.53631 5.31401
137 4YMH SAH 0.00002326 0.50305 5.31401
138 4KRG SAH 0.000003248 0.50286 5.31401
139 1FP1 SAH 0.0000659 0.4521 5.31401
140 3VSE SAH 0.00002364 0.44867 5.31401
141 1V6A TRE 0.005218 0.44388 5.31401
142 3SQP FAD 0.03256 0.4315 5.31401
143 5DNK SAH 0.00006825 0.42982 5.31401
144 2CDU FAD 0.003872 0.42467 5.31401
145 4R6W SAH 0.0001688 0.40913 5.31401
146 4REP FAD 0.01136 0.40726 5.31401
147 5CDH TLA 0.02099 0.40005 5.31401
148 2PHT MAN MAN MAN 0.01824 0.41413 5.55556
149 2GMP NAG MAN 0.01883 0.41204 5.55556
150 3CTY FAD 0.009186 0.41598 5.64263
151 5JJR SAH 0.000004587 0.54464 5.7971
152 3EVG SAH 0.000005053 0.5428 5.7971
153 5CUQ NSC 0.000009268 0.53247 5.7971
154 1XDS SAM 0.0005902 0.46659 5.7971
155 1QZZ SAM 0.001001 0.45588 5.7971
156 1UWK NAD 0.002391 0.44312 5.7971
157 1GET FAD 0.01218 0.42411 5.7971
158 1GET NAP 0.01291 0.42411 5.7971
159 4NZ6 DLY 0.01235 0.4237 5.7971
160 4J7U NAP 0.007174 0.41898 5.7971
161 4J7U YTZ 0.007174 0.41898 5.7971
162 1T36 ORN 0.01633 0.41509 5.7971
163 3L9W GSH 0.0007094 0.40261 5.7971
164 4OKD GLC GLC GLC 0.03041 0.40188 5.7971
165 4RSL FAD 0.01322 0.40133 5.7971
166 1HGX 5GP 0.01329 0.41524 6.01093
167 1LES GLC FRU 0.02455 0.40174 6.07735
168 3R51 MMA 0.006335 0.43848 6.25
169 2PX8 SAH 0.00001139 0.52739 6.28019
170 2PXX SAH 0.0001915 0.46915 6.28019
171 1JJ7 ADP 0.006202 0.44767 6.28019
172 4BLW AMP 0.001108 0.44591 6.28019
173 4BLW SAH 0.001076 0.43645 6.28019
174 1JXN MFU 0.007494 0.43379 6.28019
175 4D7E FAD 0.002548 0.4326 6.28019
176 2NVK NAP 0.008316 0.43028 6.28019
177 1O97 AMP 0.01448 0.41476 6.28019
178 1O97 FAD 0.01448 0.41476 6.28019
179 1YQT ADP 0.01933 0.41445 6.28019
180 3EVF SAH 0.00002517 0.41355 6.28019
181 3CX8 GSP 0.0008946 0.40655 6.28019
182 1EXF GLY 0.008069 0.40613 6.28019
183 4JLS 3ZE 0.01327 0.42107 6.57895
184 1GXU 2HP 0.002257 0.45245 6.59341
185 2JBH 5GP 0.01158 0.41826 6.76329
186 5U8U FAD 0.01601 0.41792 6.76329
187 4AT0 FAD 0.01402 0.4102 6.76329
188 4YRY FAD 0.01382 0.40626 6.76329
189 4YRY NAD 0.02064 0.40626 6.76329
190 1G0N PHH 0.01701 0.40133 6.76329
191 1KMQ GNP 0.004209 0.40518 7.06522
192 3AD8 NAD 0.01103 0.40261 7.07071
193 3C6K MTA 0.0005464 0.46177 7.08661
194 3C6K SPD 0.0005464 0.46177 7.08661
195 1LFD GNP 0.004198 0.40854 7.18563
196 4XOI GTP 0.004215 0.40684 7.22222
197 2WPF WPF 0.01299 0.43461 7.24638
198 2WPF FAD 0.01393 0.43313 7.24638
199 2QQC AG2 0.03113 0.40049 7.54717
200 4QM7 GTP 0.01856 0.40386 7.60234
201 3BGD SAH 0.000138 0.45861 7.72947
202 1BZL FAD 0.007907 0.44559 7.72947
203 4MIG G3F 0.005041 0.43116 7.72947
204 4X7Y SAH 0.003911 0.42974 7.72947
205 3LAD FAD 0.005576 0.42386 7.72947
206 2O07 MTA 0.0003116 0.41863 7.72947
207 3BGD PM6 0.0004129 0.41484 7.72947
208 2D2F ADP 0.02782 0.40627 7.72947
209 2O07 SPD 0.0003704 0.40538 7.72947
210 1FEC FAD 0.01945 0.40294 7.72947
211 4LHW GNP 0.002835 0.40282 8.04598
212 3TNF GNP 0.007758 0.40037 8.04598
213 1I9G SAM 0.0000002875 0.58303 8.21256
214 3DXY SAM 0.00003002 0.53361 8.21256
215 1ZGA SAH 0.00008771 0.50523 8.21256
216 3LST SAH 0.0003884 0.47506 8.21256
217 5F8F SFG 0.00007064 0.44818 8.21256
218 3T7S SAM 0.0002335 0.44225 8.21256
219 1T5C ADP 0.02272 0.41283 8.21256
220 5XDR ADP 0.01345 0.40682 8.21256
221 5EB4 FAD 0.01399 0.40419 8.21256
222 3QWI CUE 0.01538 0.40328 8.21256
223 3QWI NAP 0.009419 0.40328 8.21256
224 3TKA SAM 0.000001054 0.55939 8.64553
225 5IL1 SAM 0.00005208 0.49855 8.69565
226 3WYF GTP 0.006425 0.40382 8.69565
227 3W5J GDP 0.01701 0.41556 8.82353
228 1FQK ALF 0.008268 0.433 8.84354
229 4OBW SAM 0.0001966 0.47335 9.17874
230 5FTW SAH 0.0002418 0.46041 9.17874
231 3MQ2 SAH 0.001309 0.4415 9.17874
232 2GDZ NAD 0.004262 0.41553 9.17874
233 3B9Q MLI 0.02495 0.41039 9.17874
234 3GJX GTP 0.004268 0.4098 9.17874
235 1FQJ ALF 0.01297 0.42239 9.52381
236 2DPM SAM 0.0000008354 0.55738 9.66184
237 2P41 SAH 0.000008045 0.53398 9.66184
238 1VE3 SAM 0.00001106 0.52794 9.66184
239 2WA2 SAM 0.0000007757 0.52609 9.66184
240 4PPF FLC 0.0109 0.43087 9.66184
241 2F5Z FAD 0.004254 0.43005 9.66184
242 2A14 SAH 0.001081 0.42947 9.66184
243 1MZV AMP 0.009581 0.41802 9.66184
244 1E6E FAD 0.01326 0.40128 9.66184
245 3NKV GNP 0.003186 0.40059 9.71429
246 3M1I GTP 0.00512 0.40649 9.94764
247 2HNK SAH 0.000007297 0.52415 10.1449
248 5GM1 SAH 0.0002553 0.44827 10.1449
249 1G6H ADP 0.006777 0.4454 10.1449
250 1GOJ ADP 0.01055 0.43517 10.1449
251 1N4W FAD 0.01632 0.4039 10.1449
252 1YFZ IMP 0.02254 0.41099 10.2439
253 3PMA SCR 0.04789 0.40289 10.3448
254 5E8J SAH 0.00001246 0.54477 10.628
255 4DMG SAM 0.00002801 0.53505 10.628
256 4PIO SAH 0.00005582 0.50206 10.628
257 4PIO AVI 0.00005483 0.50089 10.628
258 5E9W SAH 0.00001309 0.45695 10.628
259 3UOY FAD 0.01782 0.4169 10.628
260 3UOY NAP 0.01782 0.4169 10.628
261 2PS1 ORO 0.01349 0.41491 10.628
262 1RYI FAD 0.01668 0.4017 10.628
263 4LWP SAH 0.000002247 0.519 11.1111
264 3A25 SAM 0.0004092 0.45944 11.1111
265 1XCL SAH 0.000105 0.42373 11.1111
266 5JCA FAD 0.01658 0.40271 11.1111
267 1P1C SAH 0.0001859 0.45478 11.5578
268 2ZIF SAM 0.0000002175 0.59514 11.5942
269 5MPT SAH 0.000002929 0.55315 11.5942
270 5E1M PRO PRO LYS ARG ILE ALA 0.0001148 0.48851 11.5942
271 5E1M SAH 0.0001148 0.48851 11.5942
272 4TQG NDP 0.008202 0.40209 11.5942
273 3EYA FAD 0.01292 0.40072 11.5942
274 1XHL NDP 0.006142 0.41129 11.7845
275 1U2Z SAH 0.00000226 0.54207 12.0773
276 5EZ7 FAD 0.01025 0.40923 12.0773
277 1YXM ADE 0.024 0.40821 12.0773
278 1QB7 ADE 0.01521 0.40813 12.0773
279 2HMT NAI 0.001917 0.41923 12.5
280 3GCZ SAM 0.000001979 0.51987 12.5604
281 2ZFU SAH 0.0001702 0.45682 12.5604
282 1ORR NAD 0.009316 0.40466 12.5604
283 4POO SAM 0.000008773 0.49913 13
284 2Q28 ADP 0.0005786 0.4486 13.0435
285 3UCL NAP 0.03187 0.40548 13.0435
286 3UCL CYH 0.02936 0.40548 13.0435
287 3UCL FAD 0.02936 0.40548 13.0435
288 2GAG NAD 0.01203 0.40416 13.1313
289 5DI9 GNP 0.005554 0.40649 13.2867
290 5UWI GNP 0.005467 0.40529 13.2867
291 5DHF GNP 0.006147 0.40316 13.2867
292 5UWS GNP 0.007226 0.40167 13.2867
293 5UWU GNP 0.006745 0.40147 13.2867
294 5UWR GNP 0.006791 0.40135 13.2867
295 5UWP GNP 0.007367 0.40132 13.2867
296 2EJU SAH 0.00001162 0.52701 13.5266
297 3OU2 SAH 0.000006576 0.49489 13.5266
298 4AZT SAM 0.0009141 0.44418 13.5266
299 4AZW SAM 0.0009652 0.42188 13.5266
300 1LSS NAD 0.001178 0.43159 13.5714
301 4HAT GNP 0.005915 0.40534 13.5714
302 4NEC SAH 0.00003977 0.51508 13.6364
303 1NW5 SAM 0.000001354 0.56115 14.0097
304 1Z3C SA8 0.0001166 0.42338 14.4928
305 2WSB NAD 0.005212 0.42322 14.4928
306 1QAN SAH 0.000000003734 0.65395 15.4589
307 5K7U SAM 0.00009612 0.45857 15.4589
308 5XVK SAH 0.001333 0.42753 15.4589
309 2V3A FAD 0.01187 0.40542 15.942
310 3A27 SAM 0.000091 0.48796 16.4251
311 5KOK S9T 0.0007006 0.45452 16.4251
312 2PT9 2MH 0.0007365 0.45358 16.4251
313 5KOK SAH 0.0001759 0.45222 16.4251
314 2PT9 S4M 0.0004266 0.45162 16.4251
315 5KOK R9T 0.002551 0.42898 16.4251
316 1TPY SAH 0.004725 0.40311 16.4251
317 1OIX GDP 0.001764 0.4242 16.7539
318 1I1N SAH 0.00000009078 0.60991 16.9082
319 3GEG NAD 0.00386 0.41459 16.9082
320 5FA8 SAM 0.0000003088 0.57781 17.3913
321 5XVQ SAH 0.00048 0.43724 17.3913
322 1KPG SAH 0.004316 0.40473 17.3913
323 1L3I SAH 0.0000001087 0.55004 17.7083
324 5E72 SAM 0.0000004936 0.56677 17.8744
325 5LOG SAH 0.00003303 0.48137 17.8744
326 1KPH SAH 0.004958 0.40225 17.8744
327 4DCM SAM 0.000000805 0.59235 18.3575
328 5JE0 AZ8 0.00003862 0.50423 18.8406
329 5JE0 SAH 0.00003862 0.50423 18.8406
330 4XUC SAM 0.00003764 0.50947 19.3237
331 4XUC 43G 0.00003764 0.50947 19.3237
332 2VDV SAM 0.00004582 0.51838 19.8068
333 3LCV SAM 0.004343 0.4063 19.8068
334 3MB5 SAM 0.0000009576 0.54553 20.2899
335 3Q87 SAM 0.000001886 0.5332 20.5882
336 5DX1 SFG 0.000001082 0.56006 20.7729
337 5DWQ SFG 0.000004294 0.53285 20.7729
338 1F3L SAH 0.000004759 0.52632 20.7729
339 5DX0 SFG 0.000007221 0.52563 20.7729
340 5DX8 SFG 0.000003759 0.52111 20.7729
341 5DXA SFG 0.000004074 0.51979 20.7729
342 3LA3 2FT 0.0308 0.40321 22.2222
343 5MGZ SAH 0.000574 0.44875 22.7053
344 3CH6 NAP 0.003802 0.44514 22.7053
345 3CH6 311 0.003802 0.44514 22.7053
346 4GQB 0XU 0.000005491 0.50548 22.7273
347 2UYQ SAM 0.001097 0.47847 23.1884
348 5HJM MTA 0.0000007969 0.57101 24.6377
349 5FA5 MTA 0.00008804 0.44387 25
350 2YX1 SFG 0.0000003421 0.52169 25.1208
351 2XVM SAH 0.000008297 0.47571 26.1307
352 1SQF SAM 0.0000007582 0.57879 31.8841
353 5UWT GNP 0.005745 0.40439 34.7826
Pocket No.: 2; Query (leader) PDB : 1WY7; Ligand: SAH; Similar sites found: 45
This union binding pocket(no: 2) in the query (biounit: 1wy7.bio1) has 23 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 4U60 SIA GAL NGA 0.02697 0.40072 1.44928
2 2GVC FAD 0.01133 0.40382 1.93237
3 2W58 ADP 0.009306 0.43636 1.9802
4 3UIE ANP 0.02016 0.4005 2.5
5 1UAD GNP 0.001742 0.42794 2.85714
6 2WHX ADP 0.01441 0.4201 2.89855
7 5BUK FAD 0.01916 0.40425 2.89855
8 2YVF NAD 0.03333 0.40355 2.89855
9 2YVF FAD 0.03237 0.40355 2.89855
10 2YY7 NAD 0.01035 0.40318 2.89855
11 1YC5 NCA 0.008809 0.40236 2.89855
12 5F2K OCA 0.009661 0.4057 3.38164
13 5F2K SAH 0.009661 0.4057 3.38164
14 2B9W FAD 0.02969 0.4028 3.38164
15 4USQ FAD 0.01305 0.40222 3.38164
16 2NCD ADP 0.02998 0.40247 3.86473
17 1S7G APR 0.01301 0.40116 3.86473
18 3BMN AX3 0.02231 0.40703 4.34783
19 2XT3 ADP 0.008074 0.43752 4.83092
20 2OBM ADP 0.03556 0.40132 4.83092
21 3KRR DQX 0.03402 0.40252 5.31401
22 1PN0 FAD 0.02621 0.40035 5.31401
23 1PN0 IPH 0.02721 0.40035 5.31401
24 2GMM MAN MAN 0.02099 0.4002 5.55556
25 3B5J 12D 0.02801 0.40133 5.7971
26 3PFG SAM 0.03731 0.41241 6.28019
27 4H4D 10E 0.009361 0.41271 6.76329
28 1WQ1 AF3 0.01506 0.41232 7.22892
29 3S5W FAD 0.009861 0.4041 7.24638
30 3Q9T FAY 0.01784 0.40027 7.24638
31 5WDR GNP 0.007119 0.40349 7.60234
32 1PS9 FAD 0.0189 0.40192 7.72947
33 5SZH GNP 0.006621 0.40483 8.37438
34 3NHB ADP 0.02732 0.40539 8.69565
35 1V5F FAD 0.0351 0.40366 8.69565
36 5J60 FAD 0.01034 0.41289 9.17874
37 1E1M FAD 0.02309 0.40658 9.66184
38 4YNU FAD 0.02071 0.4027 11.1111
39 4YNU LGC 0.02424 0.4027 11.1111
40 5HSA FAS 0.01879 0.40204 11.1111
41 3CGD COA 0.0455 0.40446 11.5942
42 3CGD FAD 0.0455 0.40446 11.5942
43 4YDS ATP 0.02933 0.40029 11.5942
44 1FP2 SAH 0.009956 0.40854 12.0773
45 1NVU GTP 0.005082 0.40974 14.4928
Pocket No.: 3; Query (leader) PDB : 1WY7; Ligand: SAH; Similar sites found: 4
This union binding pocket(no: 3) in the query (biounit: 1wy7.bio2) has 24 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 5E5U MLI 0.003215 0.40443 4.83092
2 2X2T GAL NGA 0.03047 0.40174 5.88235
3 4CIB 7UZ 0.02826 0.40528 7.24638
4 1VHT BA3 0.01551 0.40018 9.17874
Pocket No.: 4; Query (leader) PDB : 1WY7; Ligand: SAH; Similar sites found: 8
This union binding pocket(no: 4) in the query (biounit: 1wy7.bio4) has 23 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 3ROE THM 0.02224 0.40233 3.38164
2 1DNP MHF 0.04496 0.40105 3.38164
3 2HV8 GTP 0.007354 0.40138 3.48837
4 5FJN BE2 0.02092 0.40331 3.86473
5 5FJN FAD 0.01843 0.40331 3.86473
6 1NM5 NAP 0.02933 0.40029 5.41872
7 2UZI GTP 0.007072 0.4021 15.3846
8 5L95 AMP 0.005056 0.40009 20
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