Receptor
PDB id Resolution Class Description Source Keywords
1X92 2.3 Å EC: 5.-.-.- CRYSTAL STRUCTURE OF PSEUDOMONAS AERUGINOSA PHOSPHOHEPTOSE ISOMERASE IN COMPLEX WITH REACTION PRODUCT D-GLYCERO-D- M ANNOPYRANOSE-7-PHOSPHATE PSEUDOMONAS AERUGINOSA MIDWEST CENTRE FOR STRUCTURAL GENOMICS SIS DOMAIN A/B PROTEIN LIPOPOLYSACCHARIDE BIOSYNTHESIS PSI PROTEIN STRUCTURE INITIATIVE MIDWEST CENTER FOR STRUCTURAL GENOMICS MCSG ISOMERASE
Ref.: STRUCTURE AND FUNCTION OF SEDOHEPTULOSE-7-PHOSPHATE ISOMERASE, A CRITICAL ENZYME FOR LIPOPOLYSACCHARIDE BIOSYNTHESIS AND A TARGET FOR ANTIBIOTIC ADJUVANTS. J.BIOL.CHEM. V. 283 2835 2008
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
M7P A:302;
B:301;
Valid;
Valid;
none;
none;
submit data
290.162 C7 H15 O10 P C([C@...
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1X92 2.3 Å EC: 5.-.-.- CRYSTAL STRUCTURE OF PSEUDOMONAS AERUGINOSA PHOSPHOHEPTOSE ISOMERASE IN COMPLEX WITH REACTION PRODUCT D-GLYCERO-D- M ANNOPYRANOSE-7-PHOSPHATE PSEUDOMONAS AERUGINOSA MIDWEST CENTRE FOR STRUCTURAL GENOMICS SIS DOMAIN A/B PROTEIN LIPOPOLYSACCHARIDE BIOSYNTHESIS PSI PROTEIN STRUCTURE INITIATIVE MIDWEST CENTER FOR STRUCTURAL GENOMICS MCSG ISOMERASE
Ref.: STRUCTURE AND FUNCTION OF SEDOHEPTULOSE-7-PHOSPHATE ISOMERASE, A CRITICAL ENZYME FOR LIPOPOLYSACCHARIDE BIOSYNTHESIS AND A TARGET FOR ANTIBIOTIC ADJUVANTS. J.BIOL.CHEM. V. 283 2835 2008
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 28 families.
1 1X92 - M7P C7 H15 O10 P C([C@H]([C....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 27 families.
1 1X92 - M7P C7 H15 O10 P C([C@H]([C....
50% Homology Family (6)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 5LU5 - M7P C7 H15 O10 P C([C@H]([C....
2 5LU7 - M7P C7 H15 O10 P C([C@H]([C....
3 2XBL - M7P C7 H15 O10 P C([C@H]([C....
4 5LTZ - I22 C7 H15 O10 P C([C@H]([C....
5 5LU6 - I22 C7 H15 O10 P C([C@H]([C....
6 1X92 - M7P C7 H15 O10 P C([C@H]([C....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: M7P; Similar ligands found: 6
No: Ligand ECFP6 Tc MDL keys Tc
1 M7P 1 1
2 GMB 0.576923 0.97561
3 GMH 0.511111 0.658537
4 289 0.511111 0.658537
5 S7P 0.421053 0.863636
6 OI7 0.4 0.863636
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1X92; Ligand: M7P; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 1x92.bio1) has 17 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 2; Query (leader) PDB : 1X92; Ligand: M7P; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 1x92.bio1) has 17 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 3; Query (leader) PDB : 1X92; Ligand: M7P; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 3) in the query (biounit: 1x92.bio1) has 17 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 4; Query (leader) PDB : 1X92; Ligand: M7P; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 1x92.bio1) has 17 residues
No: Leader PDB Ligand Sequence Similarity
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