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Receptor
PDB id Resolution Class Description Source Keywords
1XG5 1.53 Å EC: 1.-.-.- STRUCTURE OF HUMAN PUTATIVE DEHYDROGENASE MGC4172 IN COMPLEX HOMO SAPIENS SHORT CHAIN DEHYDROGENASE HUMAN SGC STRUCTURAL GENOMICS STRUCTURAL GENOMICS CONSORTIUM OXIDOREDUCTASE
Ref.: STRUCTURAL GENOMICS CONSORTIUM: STRUCTURE OF THE PU HUMAN DEHYDROGENASE MGC4172 TO BE PUBLISHED
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ACY A:1401;
C:1402;
D:1403;
Invalid;
Invalid;
Invalid;
none;
none;
none;
submit data
60.052 C2 H4 O2 CC(=O...
NAP A:1301;
B:1302;
C:1303;
D:1304;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
submit data
743.405 C21 H28 N7 O17 P3 c1cc(...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1XG5 1.53 Å EC: 1.-.-.- STRUCTURE OF HUMAN PUTATIVE DEHYDROGENASE MGC4172 IN COMPLEX HOMO SAPIENS SHORT CHAIN DEHYDROGENASE HUMAN SGC STRUCTURAL GENOMICS STRUCTURAL GENOMICS CONSORTIUM OXIDOREDUCTASE
Ref.: STRUCTURAL GENOMICS CONSORTIUM: STRUCTURE OF THE PU HUMAN DEHYDROGENASE MGC4172 TO BE PUBLISHED
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 318 families.
1 1XG5 - NAP C21 H28 N7 O17 P3 c1cc(c[n+]....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 280 families.
1 1XG5 - NAP C21 H28 N7 O17 P3 c1cc(c[n+]....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 187 families.
1 1XG5 - NAP C21 H28 N7 O17 P3 c1cc(c[n+]....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: NAP; Similar ligands found: 123
No: Ligand ECFP6 Tc MDL keys Tc
1 NAP 1 1
2 NA0 0.881356 0.986301
3 TAP 0.872881 0.934211
4 NDO 0.840336 0.972603
5 NAD 0.811966 0.986111
6 N01 0.733871 0.958904
7 A3D 0.712 0.972603
8 NBP 0.707692 0.935065
9 NHD 0.68254 0.958904
10 NJP 0.661417 0.972973
11 NFD 0.658915 0.934211
12 NXX 0.619048 0.959459
13 DND 0.619048 0.959459
14 AMP NAD 0.606061 0.958904
15 ZID 0.605839 0.972603
16 NAQ 0.59854 0.922078
17 ATR 0.59292 0.917808
18 NAE 0.591241 0.946667
19 NDE 0.58042 0.986301
20 A22 0.571429 0.958904
21 NAJ 0.567164 0.986111
22 A2R 0.563025 0.932432
23 NDC 0.561644 0.922078
24 NA7 0.552846 0.907895
25 ODP 0.551471 0.935065
26 A2P 0.539823 0.930556
27 8ID 0.537313 0.910256
28 NPW 0.525547 0.8875
29 NZQ 0.521739 0.910256
30 CNA 0.521739 0.959459
31 NDP 0.514493 0.922078
32 PO4 PO4 A A A A PO4 0.503937 0.930556
33 1DG 0.503401 0.922078
34 DG1 0.503401 0.922078
35 TXP 0.5 0.922078
36 NMN AMP PO4 0.492958 0.921053
37 XNP 0.492958 0.875
38 25L 0.492308 0.958904
39 25A 0.492063 0.972222
40 NMN 0.486726 0.888889
41 NGD 0.485714 0.935065
42 9JJ 0.481707 0.8875
43 2AM 0.477876 0.891892
44 ADP 0.458333 0.945205
45 PAP 0.451613 0.931507
46 A2D 0.445378 0.945205
47 AN2 0.442623 0.932432
48 7L1 0.441558 0.777778
49 ADP PO3 0.44 0.944444
50 SAP 0.44 0.896104
51 AGS 0.44 0.896104
52 M33 0.439024 0.906667
53 AR6 AR6 0.438849 0.945205
54 BA3 0.438017 0.945205
55 OAD 0.43609 0.92
56 ADP BMA 0.43609 0.92
57 DQV 0.435714 0.958904
58 HEJ 0.435484 0.945205
59 ATP 0.435484 0.945205
60 OOB 0.435115 0.958904
61 B4P 0.434426 0.945205
62 AP5 0.434426 0.945205
63 GAP 0.433071 0.92
64 0WD 0.432432 0.922078
65 2A5 0.432 0.87013
66 5FA 0.432 0.945205
67 AQP 0.432 0.945205
68 AT4 0.430894 0.907895
69 00A 0.428571 0.909091
70 DAL AMP 0.427481 0.932432
71 CA0 0.427419 0.92
72 ADP ALF 0.426357 0.871795
73 ALF ADP 0.426357 0.871795
74 9X8 0.425373 0.871795
75 ACP 0.424 0.92
76 NAJ PZO 0.423841 0.897436
77 9SN 0.423358 0.897436
78 ADP VO4 0.423077 0.932432
79 VO4 ADP 0.423077 0.932432
80 WAQ 0.422222 0.884615
81 V3L 0.421875 0.945205
82 ACQ 0.421875 0.92
83 ADQ 0.421053 0.92
84 AR6 0.420635 0.918919
85 APR 0.420635 0.918919
86 ATP A A A 0.42029 0.958333
87 CO7 0.419753 0.786517
88 3OD 0.419118 0.92
89 1ZZ 0.419118 0.841463
90 DLL 0.41791 0.958904
91 AD9 0.417323 0.92
92 NAX 0.416667 0.875
93 OVE 0.416667 0.857143
94 MYR AMP 0.416058 0.841463
95 AV2 0.415385 0.868421
96 A3P 0.414634 0.944444
97 NNR 0.414414 0.72973
98 OMR 0.413793 0.831325
99 6YZ 0.412214 0.92
100 ANP 0.410853 0.92
101 A1R 0.410448 0.860759
102 ABM 0.409836 0.893333
103 A 0.408333 0.944444
104 AMP 0.408333 0.944444
105 SON 0.408 0.933333
106 PPS 0.407692 0.829268
107 5AL 0.407692 0.932432
108 NAI 0.406897 0.909091
109 7D3 0.406504 0.857143
110 ADX 0.404762 0.829268
111 ATF 0.40458 0.907895
112 3UK 0.404412 0.945946
113 TYR AMP 0.404255 0.921053
114 AMP DBH 0.404255 0.894737
115 139 0.402685 0.875
116 50T 0.401575 0.906667
117 SRP 0.401515 0.907895
118 A A 0.40146 0.972222
119 B5V 0.40146 0.933333
120 A3R 0.4 0.860759
121 3AM 0.4 0.90411
122 B5M 0.4 0.921053
123 FA5 0.4 0.933333
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1XG5; Ligand: NAP; Similar sites found with APoc: 785
This union binding pocket(no: 1) in the query (biounit: 1xg5.bio2) has 32 residues
No: Leader PDB Ligand Sequence Similarity
1 1LNX URI None
2 1ZEI CRS None
3 1SC6 NAD 0.716846
4 1KYQ NAD 0.729927
5 4LZB URA 1.2605
6 4YGM URA 1.2931
7 3OJO NAD 1.43369
8 3B1F NAD 1.43369
9 5T9E NAP 1.47601
10 5T9F TYR 1.47601
11 5T9F NAP 1.47601
12 2P3V SRT 1.5625
13 2HNK SAH 1.67364
14 3I6I NDP 1.79211
15 1ZH8 NAP 1.79211
16 1X87 NAD 1.79211
17 3GRU AMP 1.79211
18 5KDX GAL TNR 1.79211
19 2B4R NAD 1.79211
20 1T26 GBD 1.79211
21 1T26 NAI 1.79211
22 4M00 SUC 1.79211
23 2B4R AES 1.79211
24 2CDC XYP 1.79211
25 2CDC XYS 1.79211
26 2CDC NAP 1.79211
27 2A14 SAH 1.90114
28 3MB5 SAM 1.96078
29 4L8V NAP 2.07715
30 3C3Y SAH 2.1097
31 3H8V ATP 2.15054
32 5E9W SAH 2.15054
33 1H9A NAP 2.15054
34 4OOE FOM 2.15054
35 4OOE NDP 2.15054
36 1DJN ADP 2.15054
37 2VUT NAD 2.15054
38 1TI7 NAP 2.15054
39 1RJW ETF 2.15054
40 1F8F NAD 2.15054
41 1VKO NAD 2.15054
42 4RLQ 3SK 2.15054
43 1O0S NAI 2.15054
44 2HQM FAD 2.15054
45 3L6C MLI 2.15054
46 2G5C NAD 2.15054
47 4PNE SAH 2.15054
48 4MOP 2H5 2.15054
49 4Z7X 3CX 2.15054
50 1NAA ABL 2.15054
51 4OPC PGT 2.15054
52 4OPC FDA 2.15054
53 1TZD ADP 2.18182
54 1O68 KIV 2.18182
55 2VT3 ATP 2.32558
56 4OBW SAM 2.33463
57 2VDV SAM 2.43902
58 4POO SAM 2.5
59 2XVM SAH 2.50896
60 2ZWA SAH 2.50896
61 5WP4 SAH 2.50896
62 3NJ4 NAD 2.50896
63 3NJ4 AFX 2.50896
64 5ZYN FAD 2.50896
65 5JJR SAH 2.50896
66 1RSG FAD 2.50896
67 4M52 FAD 2.50896
68 3LZW FAD 2.50896
69 3VPH OXM 2.50896
70 3VPH NAD 2.50896
71 1GQ2 NAP 2.50896
72 3LZW NAP 2.50896
73 4AP3 FAD 2.50896
74 4AP3 NAP 2.50896
75 4V15 PLP 2.50896
76 4RPL 3UC 2.50896
77 4RPL FAD 2.50896
78 1SAY PYR 2.50896
79 3QOX SAH 2.50896
80 2RGJ FAD 2.50896
81 5JY6 NAD 2.50896
82 5MW4 5JU 2.50896
83 3T4L ZEA 2.59259
84 5G6U TRP 2.68199
85 3HGM ATP 2.72109
86 1LTH NAD 2.86738
87 5LD5 NAD 2.86738
88 5MDH NAD 2.86738
89 1GAD NAD 2.86738
90 4KIB SAH 2.86738
91 3BAZ NAP 2.86738
92 3G2O SAM 2.86738
93 1PL6 572 2.86738
94 5AYV NAP 2.86738
95 2JJQ SAH 2.86738
96 2PZM UDP 2.86738
97 2PZM NAD 2.86738
98 3VSE SAH 2.86738
99 1U1I NAD 2.86738
100 1PL6 NAD 2.86738
101 1EBF NAD 2.86738
102 4ARU TLA 2.86738
103 2B5W NAP 2.86738
104 5X20 NAD 2.86738
105 2CVQ NDP 2.86738
106 3H9E NAD 2.86738
107 4MDH NAD 2.86738
108 1YQZ FAD 2.86738
109 2VYN NAD 2.86738
110 4LWP SAH 2.86738
111 6ECW SAH 2.86738
112 4AT0 FAD 2.86738
113 5XLX SAH 2.86738
114 1LLU NAD 2.86738
115 5UAO FAD 2.86738
116 3GXO SAH 2.86738
117 5AYV KPL 2.86738
118 1HDR NAD 2.86885
119 4RHE FMN 2.87081
120 5E1M SAH 2.90456
121 1DEK DGP 2.90456
122 1XFF GLU 2.91667
123 1O6Z NAD 2.9703
124 1BC5 SAH 2.97398
125 5N2I NAP 3.01724
126 5LUB 3Y7 3.05344
127 5ZI2 NAD 3.18841
128 5ZI2 ADP 3.18841
129 1OC2 NAD 3.22581
130 1OC2 TDX 3.22581
131 5MPT SAH 3.22581
132 3V1Y NAD 3.22581
133 6GKV SAH 3.22581
134 3CMC NAD 3.22581
135 2V7B BEZ 3.22581
136 2JHP SAH 3.22581
137 2CDU ADP 3.22581
138 3CIF NAD 3.22581
139 1DSS NAD 3.22581
140 2WPB ZZI 3.22581
141 3MCT SAH 3.22581
142 1J0X NAD 3.22581
143 3CIF G3H 3.22581
144 5V8E CIT 3.22581
145 1LVL NAD 3.22581
146 2JK0 ASP 3.22581
147 4BWL MN9 3.22581
148 5NA1 FAD 3.22581
149 6FP4 E1T 3.22581
150 6FYZ EBE 3.22581
151 6FP4 FAD 3.22581
152 1USI PHE 3.22581
153 1V8B NAD 3.22581
154 5E58 CPZ 3.22581
155 1GPM CIT 3.22581
156 4D04 FAD 3.22581
157 4D04 NAP 3.22581
158 3TWO NDP 3.22581
159 5FJN FAD 3.22581
160 5FJN BE2 3.22581
161 5Y8L NAD 3.22581
162 5Y8L HUI 3.22581
163 1FEC FAD 3.22581
164 1PN0 FAD 3.22581
165 4IDT T28 3.22581
166 1R37 NAD 3.22581
167 3M89 GSP 3.22581
168 4JLS 3ZE 3.28947
169 4YMH SAH 3.33333
170 3RFV NAI 3.37079
171 3RFV 15L 3.37079
172 1YS4 NAP 3.38983
173 5MGZ SAH 3.38983
174 2D2I NAP 3.42105
175 1YNS HPO 3.44828
176 2TOH HBI 3.49854
177 4Z3E GAL NGA GLA BGC GAL 3.53535
178 4LHD GLY 3.58423
179 1V59 NAD 3.58423
180 2IXB NAD 3.58423
181 1G60 SAM 3.58423
182 1Q0H NDP 3.58423
183 1RJD SAM 3.58423
184 1C0I FAD 3.58423
185 1C0I BE2 3.58423
186 1Q0H FOM 3.58423
187 5H81 NAP 3.58423
188 1KOL NAD 3.58423
189 5UAV NDP 3.58423
190 4DCM SAM 3.58423
191 1F8G NAD 3.58423
192 3S5W NAP 3.58423
193 3UDZ ADP 3.58423
194 5F1V 3VN 3.58423
195 2IXB A2G 3.58423
196 1G55 SAH 3.58423
197 5UAV TFB 3.58423
198 4CJX NAP 3.58423
199 1OJ4 ANP 3.58423
200 1NW5 SAM 3.58423
201 1H6C SIN 3.58423
202 2YX1 SFG 3.58423
203 1K3T BRZ 3.58423
204 1RYD NDP 3.58423
205 1WP4 NDP 3.58423
206 1RYI GOA 3.58423
207 1RYI FAD 3.58423
208 1KEV NDP 3.58423
209 1OMO NAD 3.58423
210 5O9F 9ON 3.69318
211 5O9F NAD 3.69318
212 5L95 AMP 3.75
213 3B20 NAD 3.83481
214 3B1J NAD 3.83481
215 5GVR LMR 3.84615
216 5DOZ NDP 3.84615
217 3CBG SAH 3.87931
218 5OOH NAP 3.8835
219 5OOH 9ZZ 3.8835
220 4HXY NDP 3.94265
221 1PJS NAD 3.94265
222 2F1K NAP 3.94265
223 1UWK NAD 3.94265
224 1UWK URO 3.94265
225 5XNC MTA 3.94265
226 5NUF NAD 3.94265
227 4RDH AMP 3.94265
228 2NVK NAP 3.94265
229 1H2B NAJ 3.94265
230 5NUE NAD 3.94265
231 4RQU NAD 3.94265
232 1CF2 NAP 3.94265
233 5KVS NAP 3.94265
234 4RDI ATP 3.94265
235 6ECU SAH 3.94265
236 1GV0 NAD 3.94265
237 4XQC NAD 3.94265
238 5Z21 NAI 3.94265
239 4XQC 13D 3.94265
240 5GM1 SAH 3.94265
241 2BRY FAD 3.94265
242 2NAD NAD 3.94265
243 4KRI SAH 3.94265
244 5A04 BGC 3.94265
245 5A04 NDP 3.94265
246 4TXI FAD 3.94265
247 4FBL SPD 3.94265
248 4D79 ATP 3.98551
249 3O5X JZG 3.98551
250 1JNR FAD 4
251 2OOR NAD 4.02299
252 1DRV A3D 4.0293
253 1EYQ NAR 4.05405
254 3C8F MT2 4.08163
255 2UVO NDG 4.09357
256 3KIH GDL 4.12371
257 2DC1 NAD 4.23729
258 3LCC SAH 4.25532
259 2DT5 NAD 4.2654
260 6EL3 NAP 4.30108
261 5MSO NAP 4.30108
262 1GUZ NAD 4.30108
263 4OHU NAD 4.30108
264 4OHU 2TK 4.30108
265 5THY SAH 4.30108
266 1WDK NAD 4.30108
267 5ZA2 NXL 4.30108
268 2XYQ SAH 4.30108
269 3OA2 NAD 4.30108
270 5THZ SAH 4.30108
271 3L4S NAD 4.30108
272 2ZJ1 ARJ 4.30108
273 1MUU NAD 4.30108
274 1MV8 NAD 4.30108
275 1R6D DAU 4.30108
276 1R6D NAD 4.30108
277 4KOA NDP 4.30108
278 2ZJ1 NAD 4.30108
279 3L4S 3PG 4.30108
280 1HYH NAD 4.30108
281 3L9W AMP 4.30108
282 4KCT PYR 4.30108
283 4CP8 MLI 4.30108
284 3ULK NDP 4.30108
285 4IF4 BEF 4.32692
286 3ABI NAD 4.38356
287 1EJ0 SAM 4.44444
288 2JBH 5GP 4.44444
289 1CER NAD 4.53172
290 4NEC SAH 4.54545
291 1SQS TLA 4.54545
292 1E7S NAP 4.6595
293 1EK6 NAI 4.6595
294 1EK6 UPG 4.6595
295 1GY8 NAD 4.6595
296 2EXX NAP 4.6595
297 1UXG NAD 4.6595
298 1UXG FUM 4.6595
299 3GGO ENO 4.6595
300 3GGO NAI 4.6595
301 1ZQ9 SAM 4.6595
302 1RM0 D6P 4.6595
303 3WGT FAD 4.6595
304 1RM0 NAI 4.6595
305 1RM4 NDP 4.6595
306 3WGT QSC 4.6595
307 1P0F NAP 4.6595
308 3LKZ SFG 4.6595
309 3OND ADN 4.6595
310 3OND NAD 4.6595
311 3WLE NAD 4.6595
312 5OKU 0L1 4.6595
313 2A92 NAI 4.6729
314 5FTW SAH 4.6875
315 5LOG SAH 4.72103
316 1J5P NAD 4.74308
317 2HMT NAI 4.86111
318 3A4V PYR 5.01792
319 3A4V NAD 5.01792
320 4GLL NAD 5.01792
321 5JGL SAM 5.01792
322 4KP7 NAP 5.01792
323 5AOV NAP 5.01792
324 1LDN NAD 5.01792
325 5JE8 NAD 5.01792
326 5DNK SAH 5.01792
327 3WQQ NDP 5.01792
328 3WQQ IB3 5.01792
329 1GTE FAD 5.01792
330 3GCZ SAM 5.01792
331 5ERG SAM 5.01792
332 4KP7 1UQ 5.01792
333 1BZL GCG 5.01792
334 1U3U BNF 5.01792
335 1U3U NAD 5.01792
336 1ZGS XMM 5.01792
337 3BP1 GUN 5.01792
338 1PS9 NAP 5.01792
339 1BZL FAD 5.01792
340 1I2B USQ 5.01792
341 1I2B NAD 5.01792
342 1I2B UPG 5.01792
343 2PWY SAH 5.03876
344 5JCM FAD 5.09978
345 5JCM NAD 5.09978
346 5BSZ SAH 5.2
347 4EUE NAI 5.26316
348 1R18 SAH 5.28634
349 4U7W NDP 5.37634
350 2C5A GDC 5.37634
351 2C5A NAD 5.37634
352 5F8F SFG 5.37634
353 2DFV NAD 5.37634
354 3H5N ATP 5.37634
355 1NVM NAD 5.37634
356 4RKX 3S9 5.37634
357 1UDB NAD 5.37634
358 1UDB UFG 5.37634
359 1HDG NAD 5.37634
360 5MIT NAP 5.37634
361 5MIT FAD 5.37634
362 5UR0 NAD 5.37634
363 2NU8 COA 5.37634
364 3UCL NAP 5.37634
365 3UCL CYH 5.37634
366 3UCL FAD 5.37634
367 3ORF NAD 5.57769
368 5EES NAP 5.66802
369 1I36 NAP 5.68182
370 1VM6 NAD 5.70175
371 3I9U DTU 5.70342
372 1LSS NAD 5.71429
373 4O1M NAD 5.73477
374 1ORR NAD 5.73477
375 1Z45 NAD 5.73477
376 3GFB NAD 5.73477
377 1A5Z NAD 5.73477
378 1KYZ SAH 5.73477
379 1NPD NAD 5.73477
380 1ZGA SAH 5.73477
381 1D1T NAD 5.73477
382 2YVJ NAI 5.73477
383 2FZW NAD 5.73477
384 1VI2 NAD 5.73477
385 1J49 NAD 5.73477
386 1D4D FAD 5.73477
387 2DVZ GLU 5.73477
388 2R0D 4IP 5.73477
389 1X7D NAD 5.73477
390 1VLH PNS 5.78035
391 1P19 IMP 5.88235
392 6ECT SAM 5.919
393 3ENV ABF 5.95745
394 2W5P CL8 6.04027
395 2PXX SAH 6.04651
396 5Z20 NAI 6.08696
397 3KO8 NAD 6.09319
398 4PIV NDP 6.09319
399 1EQ2 NAP 6.09319
400 1E5Q NDP 6.09319
401 5KKA 6V0 6.09319
402 5W7M SAH 6.09319
403 5W7K SAH 6.09319
404 4DMG SAM 6.09319
405 6A0S HSE 6.09319
406 6A0S NDP 6.09319
407 4J36 1HR 6.09319
408 4J36 FAD 6.09319
409 2WPF WPF 6.09319
410 4YCA NDP 6.09319
411 5YEC ATP 6.09319
412 1GR0 NAD 6.09319
413 2GSD NAD 6.09319
414 1QO8 FAD 6.09319
415 1LJ8 NAD 6.09319
416 2GCG NDP 6.09319
417 5O96 SAM 6.12245
418 3P13 RIP 6.25
419 2Y6Q FAD 6.28141
420 2Y6Q I7T 6.28141
421 5ULP KB1 6.34328
422 2VHW NAI 6.36605
423 5BW4 SAM 6.36704
424 2WTN FER 6.3745
425 5J6Y GLC 6.38298
426 5J6Y BGC 6.38298
427 6BWL NAD 6.45161
428 1WVG APR 6.45161
429 1BW9 NAD 6.45161
430 2Q1S NAI 6.45161
431 1PCA CIT 6.45161
432 1BXG NAD 6.45161
433 3A06 NDP 6.45161
434 1SOW NAD 6.45161
435 4XYB NDP 6.45161
436 1FP2 SAH 6.45161
437 3A06 FOM 6.45161
438 5KOK SAH 6.45161
439 1Y8Q ATP 6.45161
440 1Q8A HCS 6.45161
441 3BOF HCS 6.45161
442 5X2N ALA 6.45161
443 3LST SAH 6.45161
444 1C1X NAD 6.45161
445 5YRV 5AD 6.45161
446 5ME4 HP4 6.56934
447 2PKA BEN 6.57895
448 1S8G DAO 6.61157
449 5W7R SAH 6.75991
450 5BJX NAD 6.81004
451 5BJX UDP 6.81004
452 5Y1G NAD 6.81004
453 5Y1G AKB 6.81004
454 4DPL NAP 6.81004
455 5CAE COA 6.81004
456 5WP5 SAH 6.81004
457 1YB5 NAP 6.81004
458 5HSA FAS 6.81004
459 1GZ4 ATP 6.81004
460 3QVP FAD 6.81004
461 1RPN NDP 6.86567
462 5JWC FAD 6.90979
463 4JK3 NAD 6.94981
464 4J4H 1J1 6.94981
465 4J4H NAI 6.94981
466 3T7S SAM 7.08955
467 4Q9N NAI 7.16846
468 1HYE NAP 7.16846
469 2DBZ NAP 7.16846
470 1O94 ADP 7.16846
471 3BXO SAM 7.16846
472 1LUA NAP 7.16846
473 2IZ1 ATR 7.16846
474 1P77 ATR 7.35294
475 3JWH SAH 7.37327
476 4XZ3 COA 7.3913
477 4XZ3 ACP 7.3913
478 2FR1 NDP 7.40741
479 2BKA NDP 7.43802
480 1RKX NAD 7.52688
481 6D6Y SAH 7.52688
482 6H45 QEI 7.52688
483 4Z0H NAD 7.52688
484 2XVE FAD 7.52688
485 2XVF FAD 7.52688
486 4R8L ASP 7.52688
487 4U8P FDA 7.52688
488 4U8P UDP 7.52688
489 4FZV SAM 7.53138
490 1D7O NAD 7.8853
491 1D7O TCL 7.8853
492 4RSL FAD 7.8853
493 4II2 ATP 7.8853
494 5OC1 FAD 7.8853
495 3RK0 AMP 8.01688
496 5IL1 SAM 8.01887
497 1NYT NAP 8.11808
498 1QAN SAH 8.19672
499 5JAQ NAI 8.24373
500 5OCQ CIT 8.24373
501 3GU3 SAH 8.24373
502 5N6C NAD 8.24373
503 5A1T NAI 8.24373
504 1PZG A3D 8.24373
505 5CWA 0GA 8.24373
506 5A1T OXM 8.24373
507 4UCI SAM 8.24373
508 2PV7 NAD 8.24373
509 3WV8 ATP 8.25688
510 2Q46 NAP 8.3004
511 5C2N NAG 8.33333
512 4TQG NDP 8.35913
513 3FSY SCA 8.43373
514 3QV1 NAD 8.53659
515 4G5H NAP 8.60215
516 4G5H UD7 8.60215
517 3SSO SAH 8.60215
518 1FP1 SAH 8.60215
519 2CVZ NDP 8.60215
520 5TVI O8N 8.69565
521 2EV9 NAP 8.74525
522 2EV9 SKM 8.74525
523 1N7G GDR 8.92388
524 1N7G NDP 8.92388
525 1I7Q PYR 8.96057
526 3ZNN 4WL 8.96057
527 3ZNN FAD 8.96057
528 1E3I CXF 8.96057
529 2E5V FAD 8.96057
530 2Z9I GLY ALA THR VAL 9.25926
531 1BXK NAD 9.319
532 1KEW NAD 9.319
533 1KEW TYD 9.319
534 2UYQ SAM 9.319
535 1EZ4 NAD 9.319
536 5DN9 NAD 9.319
537 3VYW SAM 9.319
538 1E1M FAD 9.319
539 1E1M NAP 9.319
540 5FA5 MTA 9.319
541 5MZI FYK 9.319
542 5MZI FAD 9.319
543 5I39 FAD 9.319
544 1TL2 NDG 9.32203
545 5ZZ6 ADP 9.61539
546 5ZZ6 NAD 9.61539
547 4D3F NAP 9.67742
548 3O9Z NAD 9.67742
549 3O9Z AKG 9.67742
550 6FDF SAH 9.67742
551 1SQF SAM 9.67742
552 5Y77 FAD 9.67742
553 2D3N GLC GLC GLC 10.0358
554 1SU2 ATP 10.0629
555 1VE3 SAM 10.1322
556 5MLR GRQ 10.219
557 5MLR NAP 10.219
558 3O7W SAM 10.3943
559 2Q0L NAP 10.3943
560 1HKU NAD 10.3943
561 3OFK SAH 10.6481
562 2X6T NAP 10.7527
563 2C29 NAP 10.7527
564 2C29 DQH 10.7527
565 5XWV NDP 10.8871
566 5XWV 8H6 10.8871
567 6DNT NAD 11.1111
568 3TLJ SAH 11.1111
569 3K0T BGC 11.1888
570 3KIF GDL 11.3208
571 5HV7 RBL 11.4695
572 4KRG SAH 11.8026
573 5ZEC NAP 11.828
574 1V35 NAI 11.828
575 2I3G NAP 11.828
576 6HDT BTN 12.0301
577 3AD8 PYC 12.1212
578 3AD8 FAD 12.1212
579 3LU1 NAD 12.1864
580 4ZRN UPG 12.1864
581 4ZRN NAD 12.1864
582 1Y1P NMN AMP PO4 12.1864
583 3C1O NAP 12.1864
584 1V6A TRE 12.5448
585 9LDT NAD 12.5448
586 4ZVV GN0 12.5448
587 9LDB NAD 12.5448
588 4ZVV NAD 12.5448
589 3KB6 NAD 12.5448
590 1VQW FAD 12.5448
591 2GVC FAD 12.5448
592 2GV8 FAD 12.5448
593 6BR7 BEF 12.782
594 2Q1W NAD 12.9032
595 5IN4 6CK 12.9121
596 5IN4 GDP 12.9121
597 5IN4 NAP 12.9121
598 4AF5 CIT 13.1579
599 6BII NAP 13.2616
600 5EIN NAP 13.2616
601 4R5M NAP 13.2616
602 4R5M 4NO 13.2616
603 1NVT NAP 13.5889
604 5J5Z FAD 13.6201
605 3G89 SAM 13.6546
606 1JAY NAP 13.6792
607 4GKV NAD 13.6905
608 5TVA AMP 13.75
609 5M58 SAH 13.913
610 4PVD NDP 13.9785
611 5DF1 NAP 13.9785
612 5DF1 58X 13.9785
613 2WA2 SAM 13.9785
614 1LDM NAD 13.9785
615 6CEP OXM 13.9785
616 6CEP NAD 13.9785
617 2GZ3 NAP 13.9785
618 1NNU NAD 14.4105
619 1NNU TCT 14.4105
620 2GN4 NDP 15.4122
621 2GN4 UD1 15.4122
622 2HK9 ATR 15.6364
623 2HK9 NAP 15.6364
624 4QTU SAM 16.2963
625 3ZIA ADP 16.3934
626 3A4T SFG 16.4234
627 6AA8 NAD 16.8459
628 3O26 NDP 17.2043
629 2YY7 NAD 17.2043
630 5X68 FAD 17.2043
631 1CDO NAD 17.9211
632 2P41 SAH 18.2796
633 5X9D 80F 18.2796
634 1QG6 NAD 18.3908
635 1QG6 TCL 18.3908
636 3EVG SAH 18.5455
637 5L4S NAP 18.9964
638 5L4S 6KX 18.9964
639 2JHF NAD 19.3548
640 5L53 NAP 20.0717
641 5K4W NAI 20.0717
642 5K4W THR 20.0717
643 5M67 3D1 20.4301
644 5M67 ADE 20.4301
645 5M67 NAD 20.4301
646 5HJM MTA 20.7885
647 1E6E FAD 21.0938
648 4W6Z 8ID 21.147
649 5CG1 NAD BBN 22.2222
650 3OIG NAD 23.3083
651 4YSX FAD 24.359
652 6F3N NAD 24.3728
653 6F3N ADN 24.3728
654 1SB8 NAD 25.448
655 1SB8 UD2 25.448
656 4J1Q NDP 26.8817
657 5E8J SAH 27.2727
658 3RJ5 NAD 30.315
659 5I7S E9P 30.4348
660 5I7S NAD 30.4348
661 1W8D NAP 30.466
662 1W73 NAP 30.466
663 2PD4 NAD 30.9091
664 2PD4 DCN 30.9091
665 4FC7 COA 31.4079
666 4FC7 NAP 31.4079
667 1W6U NAP 31.8996
668 3H4V DVP 31.8996
669 3H4V NAP 31.8996
670 1G0N PHH 32.2581
671 1G0N NDP 32.2581
672 1XSE NDP 32.6165
673 4D42 W0I 32.6165
674 4D42 NAP 32.6165
675 3AFN NAP 33.7209
676 1OAA OAA 33.9768
677 1E6W NAD 35
678 5Z2L NDP 35.102
679 3ZV6 NAD 35.1254
680 3ZV6 4HB 35.1254
681 4K26 SFF 35.1449
682 4K26 NDP 35.1449
683 1E3W NAD 35.249
684 1U7T TDT 35.249
685 1U7T NAD 35.249
686 1A27 NAP 35.8423
687 1GZ6 NAI 35.8423
688 3HB5 NAP 35.8423
689 6CI9 NAP 36.2934
690 2GDZ NAD 36.7041
691 2AE2 NAP 37.3077
692 2AE2 PTO 37.3077
693 4J7U YTZ 37.6344
694 4J7U NAP 37.6344
695 6F9Q NAD 38.6029
696 5EJ2 NAD 38.7097
697 3O03 NAP 38.7097
698 3CH6 NAP 38.7097
699 3CH6 311 38.7097
700 1XHL NDP 39.0681
701 1XHL TNE 39.0681
702 2WYV NAD 39.0805
703 1N5D NDP 39.4265
704 3OJF IMJ 39.4265
705 3OJF NDP 39.4265
706 1WMA NDP 39.4265
707 1WMA AB3 39.4265
708 5B4T 3HR 39.6154
709 5B4T NAD 39.6154
710 1Z6Z NAP 40.1434
711 3V1U NAD 40.1434
712 4QED NAP 40.3226
713 1X1T NAD 40.3846
714 1FK8 NAD 40.4669
715 2VZ0 D64 40.6716
716 2VZ0 NAP 40.6716
717 2WD7 NAP 40.6716
718 1ZEM NAD 40.8397
719 3WXB NDP 40.8602
720 2DKN NAI 41.5686
721 2B4Q NAP 41.6667
722 2DTX BMA 41.6667
723 3QWI NAP 41.8519
724 3QWI CUE 41.8519
725 1XKQ NDP 41.9355
726 1ZBQ NAD 41.9355
727 1AE1 NAP 42.1245
728 1HDC CBO 42.5197
729 3NUG NAD 42.915
730 1UZN NAP 42.915
731 5OVK NDP 42.9688
732 5OJI NAP 43.0769
733 5OJI ISN 43.0769
734 3AY6 BGC 43.1227
735 3AY6 NAI 43.1227
736 2Q2V NAD 43.1373
737 4URF NAD 43.1452
738 3VZS NAP 43.1907
739 3VZS CAA 43.1907
740 2CFC NAD 43.2
741 2CFC KPC 43.2
742 5OVL NAP 43.3692
743 4ZA2 NAD 43.4783
744 1YXM ADE 43.7276
745 1H5Q NAP 43.7736
746 3ICC NAP 43.9216
747 2RH4 EMO 44.0433
748 2WSB NAD 44.0945
749 5O42 BGC 44.1606
750 5O42 NAD 44.1606
751 5O42 9JW 44.1606
752 1NFQ NAI 44.6154
753 1PR9 NAP 44.6721
754 3D3W NAP 44.6721
755 3OID NDP 44.9612
756 4CM8 NAP 45.5197
757 4CM9 NAP 45.5197
758 3BMN NAP 45.5197
759 4CLR NAP 45.5197
760 4CMI NAP 45.5197
761 3BMO NAP 45.5197
762 3JQF NAP 45.5197
763 3JQ9 NAP 45.5197
764 3BMQ NAP 45.5197
765 4CM4 NAP 45.5197
766 3JQG NAP 45.5197
767 4CLO NAP 45.5197
768 4CME NAP 45.5197
769 3JQB NAP 45.5197
770 3JQ8 NAP 45.5197
771 4CM9 YGL 45.5197
772 3SJ7 NDP 45.6349
773 1ZK4 NAP 45.8167
774 1ZK4 AC0 45.8167
775 3JQA NAP 45.8781
776 3JQ7 NAP 45.8781
777 4CQM NAP 45.9016
778 1GEE NAD 45.977
779 1VL8 NAP 46.0674
780 1GEG NAD 46.0938
781 2BD0 NAP 46.3115
782 1Q7B NAP 47.1311
783 4NBT NAD 47.5
784 1O5I NAD 48.1928
785 3RKR NAP 48.855
786 2ZAT NAP 50
Pocket No.: 2; Query (leader) PDB : 1XG5; Ligand: NAP; Similar sites found with APoc: 71
This union binding pocket(no: 2) in the query (biounit: 1xg5.bio2) has 32 residues
No: Leader PDB Ligand Sequence Similarity
1 3DXY SAM None
2 3SQP FAD 1.79211
3 4ZNO SUC 1.79211
4 2Q7V FAD 2.15054
5 1NAA 6FA 2.15054
6 4N49 SAM 2.50896
7 2F5X ASP 2.50896
8 4M52 M52 2.50896
9 5CDH TLA 2.86738
10 1M3U KPL 3.0303
11 6DUB SAH 3.15315
12 1ZK7 FAD 3.21199
13 1IT7 GUN 3.22581
14 5UQD AKG 3.22581
15 3MAG SAH 3.22581
16 5CUQ NSC 3.22581
17 1YY5 FAD 3.22581
18 4ISS TAR 3.58423
19 1T9D P22 3.58423
20 4D52 GXL 3.58423
21 2QA1 FAD 3.58423
22 3S5W FAD 3.58423
23 1H6C NDP 3.58423
24 4MIG G3F 3.58423
25 6AR9 3L4 3.67647
26 5OLK DTP 3.72093
27 2A8X FAD 3.94265
28 2KIN ADP 4
29 5ZW3 SAH 4
30 4JDR FAD 4.00844
31 6GAS FAD 4.30108
32 1GPE FAD 4.30108
33 1H74 ILE 4.30108
34 4BG4 ARG 4.6595
35 4BHL ARG 4.6595
36 1Q9I FAD 4.6595
37 1Q9I TEO 4.6595
38 3TKY N7I 4.6595
39 3F81 STT 4.91803
40 1ONI BEZ 5.07246
41 1OLT SAM 5.37634
42 1KJ8 GAR 5.37634
43 4H3P ANP 5.37634
44 2HIM ASN 5.37634
45 4P83 U5P 5.49451
46 1VC9 ATP 5.55556
47 2HUI GLV 5.73477
48 5ODQ 9SB 5.73477
49 1QK3 5GP 6.00858
50 2WPF FAD 6.09319
51 4EZD SEY 6.09319
52 3C3D FO1 6.09319
53 1DJL NAP 6.28019
54 4YEF 4CQ 6.74157
55 3PT9 SAH 6.81004
56 5EOW FAD 6.91358
57 1H82 FAD 6.99153
58 1H82 GZZ 6.99153
59 2BMB PMM 7.16846
60 4RF7 ARG 7.16846
61 5E72 SAM 7.52688
62 2GMH FAD 8.96057
63 5DNC ASN 10.3943
64 5HWK BEZ 10.8333
65 4JCA CIT 11.976
66 4TO8 FLC 12.1864
67 3A25 SAM 14.2857
68 3QFA FAD 14.3369
69 5GZZ GSH 14.6789
70 2PX8 SAH 14.8699
71 5U8U FAD 16.4875
Pocket No.: 3; Query (leader) PDB : 1XG5; Ligand: NAP; Similar sites found with APoc: 114
This union binding pocket(no: 3) in the query (biounit: 1xg5.bio2) has 31 residues
No: Leader PDB Ligand Sequence Similarity
1 3W6G FLC None
2 5YRL GLC GLC None
3 3FRH SAH None
4 2XZ9 PYR 0.716846
5 4MO2 FDA 1.07527
6 4ZCC FAD 1.19048
7 4ZCC NAI 1.19048
8 3GF4 FAD 1.79211
9 3GF4 UPG 1.79211
10 3NJQ NJQ 2.07254
11 5DX1 SFG 2.15054
12 5DX8 SFG 2.15054
13 5DWQ SFG 2.15054
14 5DXA SFG 2.15054
15 5DX0 SFG 2.15054
16 4PQG NAG 2.15054
17 1H5R THM 2.15054
18 1IM8 SAI 2.45902
19 4UP3 NDP 2.50896
20 2RHO GDP 2.50896
21 1DKU AP2 2.50896
22 3HAD NAD 2.50896
23 5MB4 NDG 2.50896
24 5YJF SAH 2.50896
25 5YJF 8WO 2.50896
26 3A27 SAM 2.57353
27 6BR8 6OU 2.77778
28 1I9G SAM 2.86738
29 2ZIF SAM 2.86738
30 2E2P ADP 2.86738
31 1NE7 16G 2.86738
32 5G3U ITW 2.86738
33 5G3U FDA 2.86738
34 1WOG 16D 2.95082
35 1RQ2 CIT 3.22581
36 2CDU FAD 3.22581
37 1GPM AMP 3.22581
38 2X61 CH 3.48837
39 3OU2 SAH 3.66972
40 3FUU ADN 3.69004
41 4P86 5GP 3.82514
42 5TCI MLI 3.94265
43 1ON3 DXX 3.94265
44 1F3L SAH 3.94265
45 1I8T FAD 3.94265
46 3X0D SAH 3.94265
47 6AIN FAD 3.94265
48 2NVK FAD 3.94265
49 5BSH PRO 3.97112
50 1UY4 XYP XYP XYP XYP 4.13793
51 4JAL SAH 4.19162
52 4OKD GLC GLC GLC 4.30108
53 2QPU QPU 4.30108
54 3LAD FAD 4.30108
55 2QPU QPS 4.30108
56 1DLJ NAI 4.30108
57 1DLJ UGA 4.30108
58 4M37 SAH 4.37318
59 4M38 SAH 4.37318
60 2BOS GLA GAL GLC NBU 4.41176
61 2BOS GLA GAL GLC 4.41176
62 1XX4 BAM 4.5977
63 4L9Z OXL 4.6595
64 2QRK AMP 4.6595
65 5JCA FAD 4.6595
66 5JCA NDP 4.6595
67 1F74 NAY 4.6595
68 4ONQ SFG 4.6595
69 3TKY SAH 4.6595
70 3A3B FMN 4.73684
71 4JBI NDP 5.01792
72 1PS9 FAD 5.01792
73 4GK9 MAN BMA MAN MAN MAN 5.01792
74 5FUB SAH 5.01792
75 1ZDQ MSM 5.01792
76 1MXI SAH 5.625
77 3A16 PXO 5.73477
78 3RUV ANP 5.73477
79 3MQ2 SAH 5.9633
80 2BZG SAH 6.03448
81 5XHA FRU 6.09319
82 2HYV UAP SGN IDS SGN IDS 6.45161
83 3HDY FAD 6.45161
84 5CAE SIN 6.81004
85 4DSG FAD 6.81004
86 4DSG UDP 6.81004
87 4XYM COA 7.3913
88 1OYF MHN 7.43802
89 3BGD SAH 7.69231
90 2JDU MFU 7.82609
91 2VVM FAD 7.8853
92 2VVL FAD 7.8853
93 4C4A SAH 8.24373
94 1MVQ MMA 8.47458
95 1T3D CYS 8.65052
96 2ZFU SAH 8.83721
97 4GQB 0XU 9.319
98 3QJ4 FAD 9.67742
99 4J51 N75 10.0358
100 1SQL GUN 10.9589
101 3DRW AMP 11.1111
102 5FII PHE 11.7647
103 1TB4 PEJ 11.828
104 3AD8 NAD 12.1212
105 2J5V RGP 12.9032
106 5BRT CH9 15.0538
107 5BRT FAD 15.0538
108 2DM6 IMN 15.7706
109 2DM6 NAP 15.7706
110 5CGE 51F 15.7706
111 1S16 ANP 17.9211
112 3RGG AIR 22.6415
113 1OGD RIP 27.4809
114 3AI3 SOE 36.8821
Pocket No.: 4; Query (leader) PDB : 1XG5; Ligand: NAP; Similar sites found with APoc: 21
This union binding pocket(no: 4) in the query (biounit: 1xg5.bio2) has 32 residues
No: Leader PDB Ligand Sequence Similarity
1 5YRG BGC GLC None
2 3WBF NAP 0.716846
3 5JIB OIA 2.15054
4 3FGZ BEF 2.34375
5 1G8S MET 2.6087
6 3KDM TES 2.75229
7 1Q8P MAN MMA 2.86738
8 5F7J ADE 3.22581
9 5T96 79J 3.22581
10 5KOX FAD 3.22581
11 5KOX RFP 3.22581
12 1V59 FAD 3.58423
13 2B1N LYS ALA SER VAL GLY 4.06504
14 6F5Z SAH 4.329
15 4IMG NGF 5.01792
16 6HKE MLT 5.34591
17 1Z0N BCD 6.25
18 3IP6 PRO 7.30337
19 6F90 MVL 7.8853
20 2F5Z FAD 8.96057
21 1JG3 ADN 22.1277
Pocket No.: 5; Query (leader) PDB : 1XG5; Ligand: NAP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 5) in the query (biounit: 1xg5.bio1) has 32 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 6; Query (leader) PDB : 1XG5; Ligand: NAP; Similar sites found with APoc: 6
This union binding pocket(no: 6) in the query (biounit: 1xg5.bio1) has 32 residues
No: Leader PDB Ligand Sequence Similarity
1 1H5S TMP 2.15054
2 2YPI PGA 2.83401
3 4XJ7 ADE 3.37079
4 5E5U MLI 5.02513
5 5JCM ISD 5.09978
6 2C7G FAD 5.37634
Pocket No.: 7; Query (leader) PDB : 1XG5; Ligand: NAP; Similar sites found with APoc: 37
This union binding pocket(no: 7) in the query (biounit: 1xg5.bio1) has 30 residues
No: Leader PDB Ligand Sequence Similarity
1 5YRJ BGC GLC None
2 4MO2 FAD 1.07527
3 1RYO OXL 1.79211
4 1YJQ NAP 1.79211
5 4ZH7 FUC GAL NAG GAL FUC 2.15054
6 1DQN IMU 2.17391
7 6GAR FAD 2.86738
8 5KMS NAD 2.86738
9 5KMS FAD 2.86738
10 3AYI HCI 2.86738
11 2OBF F83 2.86738
12 2OBF SAH 2.86738
13 1LCF OXL 3.22581
14 2EJU SAH 3.22581
15 1REO FAD 3.22581
16 2DKH FAD 3.22581
17 3NYC IAR 3.58423
18 3NYC FAD 3.58423
19 2CUN 3PG 3.94265
20 4C3Y FAD 3.94265
21 2JB2 FAD 4.6595
22 2JB2 PHE 4.6595
23 2C7G ODP 5.37634
24 5OSW DIU 5.73477
25 4EA7 JB2 6.36364
26 4EA7 COA 6.36364
27 3HDY FDA 6.45161
28 3HDY GDU 6.45161
29 2UYN 2KT 7.75194
30 2UYP PPI 7.75194
31 4IV9 FAD 8.24373
32 2ZXI FAD 9.319
33 2IID FAD 10.0358
34 2IID PHE 10.0358
35 2Q0L FAD 10.3943
36 3AB1 FAD 12.1864
37 5TWB FAD 16.8459
Pocket No.: 8; Query (leader) PDB : 1XG5; Ligand: NAP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 8) in the query (biounit: 1xg5.bio1) has 32 residues
No: Leader PDB Ligand Sequence Similarity