Receptor
PDB id Resolution Class Description Source Keywords
1XQP 1.69 Å EC: 4.-.-.- CRYSTAL STRUCTURE OF 8-OXOGUANOSINE COMPLEXED PA-AGOG, 8-OXO DNA GLYCOSYLASE FROM PYROBACULUM AEROPHILUM PYROBACULUM AEROPHILUM HELIX-HAIRPIN-HELIX 8-OXOGUANINE DNA GLYCOSYLASE ARCHAEA P.AEROPHILUM PA-AGOG-8-OXOGUANOSINE COMPLEX DNA REPAIR L
Ref.: A DNA GLYCOSYLASE FROM PYROBACULUM AEROPHILUM WITH 8-OXOGUANINE BINDING MODE AND A NONCANONICAL HELIX-HAIRPIN-HELIX STRUCTURE STRUCTURE V. 13 87 2005
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
8HG A:257;
A:258;
Valid;
Valid;
none;
none;
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283.241 C10 H13 N5 O5 C1[C@...
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1XQP 1.69 Å EC: 4.-.-.- CRYSTAL STRUCTURE OF 8-OXOGUANOSINE COMPLEXED PA-AGOG, 8-OXO DNA GLYCOSYLASE FROM PYROBACULUM AEROPHILUM PYROBACULUM AEROPHILUM HELIX-HAIRPIN-HELIX 8-OXOGUANINE DNA GLYCOSYLASE ARCHAEA P.AEROPHILUM PA-AGOG-8-OXOGUANOSINE COMPLEX DNA REPAIR L
Ref.: A DNA GLYCOSYLASE FROM PYROBACULUM AEROPHILUM WITH 8-OXOGUANINE BINDING MODE AND A NONCANONICAL HELIX-HAIRPIN-HELIX STRUCTURE STRUCTURE V. 13 87 2005
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 46 families.
1 1XQP - 8HG C10 H13 N5 O5 C1[C@@H]([....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 44 families.
1 1XQP - 8HG C10 H13 N5 O5 C1[C@@H]([....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 35 families.
1 1XQP - 8HG C10 H13 N5 O5 C1[C@@H]([....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: 8HG; Similar ligands found: 8
No: Ligand ECFP6 Tc MDL keys Tc
1 8HG 1 1
2 8OG 0.742857 0.888889
3 8GD 0.706667 0.901235
4 8DG 0.670886 0.901235
5 8GM 0.481481 0.839506
6 G8D 0.465116 0.851852
7 8GT 0.454545 0.851852
8 8DA 0.454545 0.934211
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1XQP; Ligand: 8HG; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 1xqp.bio1) has 7 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 2; Query (leader) PDB : 1XQP; Ligand: 8HG; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 1xqp.bio1) has 16 residues
No: Leader PDB Ligand Sequence Similarity
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