Receptor
PDB id Resolution Class Description Source Keywords
1YGC 2 Å EC: 3.4.21.21 SHORT FACTOR VIIA WITH A SMALL MOLECULE INHIBITOR HOMO SAPIENS INVERTED OXY-ANION HOLE HYDROLASE
Ref.: A SELECTIVE, SLOW BINDING INHIBITOR OF FACTOR VIIA BINDS TO A NONSTANDARD ACTIVE SITE CONFORMATION AND ATTENUATES THROMBUS FORMATION IN VIVO. J.BIOL.CHEM. V. 280 9160 2005
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
905 H:1;
Valid;
none;
Ki = 0.35 nM
545.583 C25 H28 F N5 O6 S [H]/N...
CA H:300;
H:538;
Part of Protein;
Part of Protein;
none;
none;
submit data
40.078 Ca [Ca+2...
SO4 H:301;
H:304;
H:308;
H:310;
H:311;
H:312;
L:302;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
none;
none;
submit data
96.063 O4 S [O-]S...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1YGC 2 Å EC: 3.4.21.21 SHORT FACTOR VIIA WITH A SMALL MOLECULE INHIBITOR HOMO SAPIENS INVERTED OXY-ANION HOLE HYDROLASE
Ref.: A SELECTIVE, SLOW BINDING INHIBITOR OF FACTOR VIIA BINDS TO A NONSTANDARD ACTIVE SITE CONFORMATION AND ATTENUATES THROMBUS FORMATION IN VIVO. J.BIOL.CHEM. V. 280 9160 2005
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 5 families.
1 1YGC Ki = 0.35 nM 905 C25 H28 F N5 O6 S [H]/N=C(/c....
2 1KLI - BEN C7 H8 N2 [H]/N=C(c1....
70% Homology Family (27)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 5TQG Ki = 0.24 nM 7KS C34 H34 F3 N5 O5 S C[C@@H]1CC....
2 4X8V Ki = 130 nM 3Z9 C34 H40 N4 O8 S CC(C)S(=O)....
3 4X8T Ki = 8.9 mM 3Z8 C9 H8 Cl N O c1cc2c(cc1....
4 5TQE Ki = 190 nM 7KQ C31 H31 N5 O5 S CN1Cc2cc(c....
5 4JZE ic50 = 0.007 uM 1NK C30 H31 N5 O6 CC(C)(C)[C....
6 1W7X Ki = 0.004 uM 413 C31 H30 N4 O5 COc1cc(ccc....
7 4X8U Ki = 3.5 mM 3ZB C9 H6 Cl N O2 c1cc2c(cc1....
8 4JYU Ki = 10 nM 1OK C28 H30 N4 O5 S CCOc1cc(cc....
9 4ISI Ki = 7.3 nM 1GG C24 H31 Cl N6 O2 [H]/N=C(/c....
10 4JZD ic50 = 0.005 uM 1NJ C28 H31 N5 O6 [H]/N=C(c1....
11 5I46 - 67O C30 H30 F N5 O4 Cc1cc2ccc1....
12 4X8S Ki = 13 mM 3Z7 C7 H7 Br O2 COc1cc(ccc....
13 5L2Z Ki = 0.06 nM 70C C37 H40 F N5 O5 Cc1cc2ccc1....
14 5U6J Ki = 23 nM 82J C31 H36 N4 O6 S CCc1cc2ccc....
15 4ZXY Ki = 920 nM 4T1 C28 H27 N5 O2 c1cc2cc(c1....
16 5L2Y Ki = 0.14 nM 70D C35 H36 F N5 O5 Cc1cc2ccc1....
17 4JYV Ki = 17 nM 1OJ C28 H30 N4 O7 S2 CCOc1cc(cc....
18 4YT7 Ki = 1.7 nM 4K1 C29 H31 F N6 O3 [H]/N=C(c1....
19 4NA9 Ki = 41 nM 1T7 C29 H26 N4 O2 [H]/N=C(c1....
20 4JZF ic50 = 0.175 uM 1NL C28 H30 N4 O7 CC(C)(C)[C....
21 5TQF Ki < 5 nM 7KR C31 H31 N5 O4 S CN1Cc2cc(c....
22 2BZ6 Ki = 0.081 uM 346 C21 H24 F N3 O5 [H]/N=C(c1....
23 4ISH Ki = 1.9 nM 1GE C31 H27 N3 O4 [H]/N=C(c1....
24 4YT6 Ki = 11 nM 4JY C28 H30 F N5 O2 [H]/N=C(c1....
25 5L30 - 70A C34 H35 N9 O3 Cc1cc2ccc1....
26 1YGC Ki = 0.35 nM 905 C25 H28 F N5 O6 S [H]/N=C(/c....
27 1KLI - BEN C7 H8 N2 [H]/N=C(c1....
50% Homology Family (119)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 3IIT ic50 = 9.5 nM D14 C26 H29 Cl N6 O3 S C[N@@]1Cc2....
2 2Q1J ic50 = 0.0008 uM FXI C28 H29 Cl F N3 O4 S CCCCN(C(=O....
3 2VVC - LZF C23 H22 Cl F N4 O4 S CO[C@H]1C[....
4 3KQC Ki = 2.2 nM LGK C28 H21 F3 N6 O4 S CS(=O)(=O)....
5 2P95 Ki = 0.43 nM ME5 C22 H20 Cl N3 O3 S c1cc(ccc1C....
6 2Y5F Ki = 2 nM XWG C25 H32 Cl N4 O4 S c1cc(sc1c2....
7 2W26 Ki = 0.4 nM RIV C19 H18 Cl N3 O5 S c1cc(ccc1N....
8 2XC4 Ki = 0.009 uM IVK C25 H21 Cl F4 N4 O3 c1cc(ccc1N....
9 3FFG Ki = 0.84 nM FFG C32 H28 F3 N7 O3 c1ccc(c(c1....
10 2P3U - 663 C23 H18 Cl3 N5 O3 S Cn1ccnc1Cc....
11 2FZZ Ki = 30 pM 5QC C31 H27 F3 N6 O3 c1ccc(c(c1....
12 3KQE Ki = 8.1 nM LGM C32 H31 N7 O2 Cc1c2c(n(n....
13 2P93 Ki = 1.5 nM ME1 C19 H16 Cl N3 O3 S c1cc(ccc1C....
14 3M37 - M37 C24 H19 F4 N5 O3 S c1ccc(c(c1....
15 2W3K ic50 = 0.08 nM L1D C29 H24 Cl F N4 O4 c1ccc(cc1)....
16 1MQ6 Ki = 7 pM XLD C23 H20 Cl3 N5 O4 S CN(Cc1csc(....
17 2VWM - LZI C27 H27 Cl F N5 O4 S c1cc(c(cc1....
18 1Z6E Ki = 0.19 nM IK8 C24 H20 F4 N8 O2 CN(C)Cc1nc....
19 2BQ7 Ki = 89 nM IID C25 H31 N3 O2 CC(C)N1CCC....
20 5K0H - 6PK C27 H31 N5 O5 S [H]/N=C(c1....
21 3KL6 ic50 = 0.00000001 M 443 C22 H26 Cl N3 O5 S c1cc(cc2c1....
22 2XBV Ki = 7 nM XBV C24 H21 Cl F3 N5 O3 c1cc(c(cc1....
23 2RA0 Ki = 15.9 nM JNJ C27 H22 F2 N8 O2 CN(C)Cc1nc....
24 2BOK Ki = 0.28 uM 784 C22 H32 N5 O2 C[N+](C)(C....
25 2XBY - 63C C26 H25 Cl F N5 O4 CNC(=O)CN1....
26 2W3I ic50 = 0.1 nM L1C C28 H22 Cl F2 N5 O4 c1cc(ccc1N....
27 2PR3 ic50 = 0.16 nM 237 C26 H25 Cl F N3 O5 S CO[C@@H]1C....
28 2VWL - LZH C23 H22 Cl F N4 O4 S c1cc(c(cc1....
29 2P3T Ki = 0.005 nM 993 C23 H19 Cl3 N6 O3 S CNc1nccn1C....
30 3LIW Ki = 0.025 uM RUP C29 H37 N5 O2 c1ccc(cc1)....
31 3Q3K ic50 = 7.4 nM D90 C23 H20 Cl N5 O2 S C[N@@]1CCc....
32 2PHB ic50 = 0.32 nM 230 C24 H22 Cl F N4 O4 CO[C@@H]1C....
33 2Y5G Ki = 146 nM FJD C22 H28 Cl N4 O3 S C[N+](C)(C....
34 2XC5 Ki = 0.062 uM OYJ C24 H21 Cl F2 N4 O5 S CS(=O)(=O)....
35 2XBW Ki = 0.01 uM 455 C23 H21 Cl F N5 O5 S c1cc(ccc1N....
36 3CS7 Ki = 0.021 nM LG0 C28 H29 F3 N4 O2 COc1ccc(cc....
37 2EI6 ic50 = 753 nM D92 C23 H26 Cl N5 O2 S C[N@@]1CCc....
38 2XC0 Ki = 0.192 uM 8NC C25 H24 F2 N4 O6 S COc1ccc(cc....
39 2JKH Ki = 9 nM BI7 C22 H28 Cl N4 O3 S C[N](C)(C)....
40 3M36 - M35 C25 H20 F4 N4 O3 S CS(=O)(=O)....
41 3KQB Ki = 0.5 nM LGJ C26 H18 F4 N6 O4 S CS(=O)(=O)....
42 2VWO - LZG C22 H19 Cl F2 N4 O3 S c1cc(c(cc1....
43 1FJS Ki = 0.11 nM Z34 C25 H24 F2 N6 O5 [H]/N=C(c1....
44 2D1J - D01 C20 H17 Cl N4 O4 S2 c1cc2c(cc(....
45 2EI7 ic50 = 16 nM D93 C23 H26 Cl N5 O2 S C[N@@]1CCc....
46 2P16 Ki = 0.08 nM GG2 C25 H25 N5 O4 COc1ccc(cc....
47 2Y5H Ki = 1620 nM Y5H C22 H28 Cl N4 O3 S C[N+](C)(C....
48 1MQ5 Ki = 1 nM XLC C24 H23 Cl3 N4 O2 S CN1CCN(CC1....
49 2VWN - H25 C22 H20 Cl F N4 O4 S c1cc(c(cc1....
50 2XBX Ki = 0.015 uM RR8 C24 H22 Cl F N4 O5 S CS(=O)(=O)....
51 2VVU - H22 C22 H20 Cl F N4 O3 S c1cc(c(cc1....
52 2P94 Ki = 0.67 nM ME4 C27 H25 Cl N4 O3 c1cc(ccc1C....
53 2VVV - H21 C20 H14 Cl F N6 O3 S c1cc(c(cc1....
54 2G00 Ki = 0.18 nM 4QC C29 H26 F3 N5 O2 CN(C)Cc1cc....
55 1V3X ic50 = 24 nM D76 C23 H24 Cl N5 O4 S2 C[N@@]1CCc....
56 3CEN Ki = 5.5 nM FXA C23 H17 Cl N4 O4 S c1ccc(c(c1....
57 2BOH Ki = 3 nM IIA C25 H27 Cl N4 O2 S CC(C)N1CCC....
58 2J38 Ki = 47 nM GS5 C19 H22 Cl N3 O5 S2 C[C@@H](C(....
59 1F0R Ki = 22 nM 815 C21 H19 N5 O3 S2 c1cc2c(cc(....
60 2Y7Z Ki = 2 nM C0Z C25 H26 Cl N3 O3 S CN(C)[C@H]....
61 1NFX Ki = 3 nM RDR C22 H21 Cl N4 O4 S2 c1cc(cc2c1....
62 2VH6 Ki = 0.2 nM GSV C23 H22 Cl F N2 O5 S3 CS(=O)(=O)....
63 2Y81 Ki = 2 nM 931 C24 H23 Cl F N3 O3 S c1cc(cc2c1....
64 1NFY Ki = 1.3 nM RTR C20 H19 Cl N4 O3 S2 c1cc(ccc1C....
65 2J4I Ki = 1 nM GSJ C23 H31 Cl N4 O6 S2 CC(C)N(CCN....
66 2UWO Ki = 2 nM 701 C18 H24 Cl N3 O5 S2 C[C@@H](C(....
67 2Y80 Ki = 9 nM 439 C25 H26 Cl N3 O3 S CN(C)[C@@H....
68 2UWL Ki = 4 nM 895 C17 H22 Cl N3 O5 S2 C[C@@H](C(....
69 2WYJ Ki = 1 nM 898 C20 H23 Cl F N3 O3 S2 C[C@@H](c1....
70 2UWP Ki = 154 nM 894 C17 H24 Cl N3 O5 S2 C[C@@H](C(....
71 4Y76 - 4O1 C25 H32 Cl N5 O5 S C[C@@H](C(....
72 2J34 Ki = 15 nM GS6 C19 H22 Cl N3 O5 S2 C[C@@H](C(....
73 1F0S Ki = 18 nM PR2 C19 H17 N5 O3 S2 c1cc2c(cc(....
74 1NFW Ki = 1.1 nM RRR C18 H17 Cl N4 O3 S2 c1cc(sc1C=....
75 2J95 Ki = 4 nM GSX C19 H22 Cl N3 O5 S3 C[C@@H](C(....
76 5TQG Ki = 0.24 nM 7KS C34 H34 F3 N5 O5 S C[C@@H]1CC....
77 4X8V Ki = 130 nM 3Z9 C34 H40 N4 O8 S CC(C)S(=O)....
78 4X8T Ki = 8.9 mM 3Z8 C9 H8 Cl N O c1cc2c(cc1....
79 5TQE Ki = 190 nM 7KQ C31 H31 N5 O5 S CN1Cc2cc(c....
80 4JZE ic50 = 0.007 uM 1NK C30 H31 N5 O6 CC(C)(C)[C....
81 1W7X Ki = 0.004 uM 413 C31 H30 N4 O5 COc1cc(ccc....
82 4X8U Ki = 3.5 mM 3ZB C9 H6 Cl N O2 c1cc2c(cc1....
83 4JYU Ki = 10 nM 1OK C28 H30 N4 O5 S CCOc1cc(cc....
84 4ISI Ki = 7.3 nM 1GG C24 H31 Cl N6 O2 [H]/N=C(/c....
85 4JZD ic50 = 0.005 uM 1NJ C28 H31 N5 O6 [H]/N=C(c1....
86 5I46 - 67O C30 H30 F N5 O4 Cc1cc2ccc1....
87 4X8S Ki = 13 mM 3Z7 C7 H7 Br O2 COc1cc(ccc....
88 5L2Z Ki = 0.06 nM 70C C37 H40 F N5 O5 Cc1cc2ccc1....
89 5U6J Ki = 23 nM 82J C31 H36 N4 O6 S CCc1cc2ccc....
90 4ZXY Ki = 920 nM 4T1 C28 H27 N5 O2 c1cc2cc(c1....
91 5L2Y Ki = 0.14 nM 70D C35 H36 F N5 O5 Cc1cc2ccc1....
92 4JYV Ki = 17 nM 1OJ C28 H30 N4 O7 S2 CCOc1cc(cc....
93 4YT7 Ki = 1.7 nM 4K1 C29 H31 F N6 O3 [H]/N=C(c1....
94 4NA9 Ki = 41 nM 1T7 C29 H26 N4 O2 [H]/N=C(c1....
95 4JZF ic50 = 0.175 uM 1NL C28 H30 N4 O7 CC(C)(C)[C....
96 5TQF Ki < 5 nM 7KR C31 H31 N5 O4 S CN1Cc2cc(c....
97 2BZ6 Ki = 0.081 uM 346 C21 H24 F N3 O5 [H]/N=C(c1....
98 4ISH Ki = 1.9 nM 1GE C31 H27 N3 O4 [H]/N=C(c1....
99 4YT6 Ki = 11 nM 4JY C28 H30 F N5 O2 [H]/N=C(c1....
100 5L30 - 70A C34 H35 N9 O3 Cc1cc2ccc1....
101 4ZAE Ki = 3.6 nM 4M1 C26 H22 Cl2 N6 O Cc1cc2c(cc....
102 5TNT ic50 = 4.9 nM 7GQ C22 H20 Cl2 N8 O2 Cc1ncn(n1)....
103 5EGM Ki = 2.4 nM 5NY C29 H24 Cl N9 O Cc1ccc2c(c....
104 4Z0K Ki = 0.462 uM 4LN C22 H22 N6 O2 Cc1ccc(c2n....
105 3LC3 Ki = 5.9 uM IYX C17 H18 N2 O2 S COc1ccc(cc....
106 4YZU Ki = 9 uM 4K6 C20 H20 N6 O Cc1cc2c(cc....
107 3K9X ic50 = 4 nM MBM C28 H32 N6 O4 Cc1cc2cc(c....
108 1G2L Ki = 57 nM T87 C29 H31 N7 O3 [H]/N=C(/c....
109 3SW2 ic50 = 13 nM FI1 C28 H29 Cl N4 O5 S c1cc(cc2c1....
110 1XKB Ki = 131 nM 4PP C23 H24 N4 O2 c1cc(cc(c1....
111 1XKA Ki = 131 nM 4PP C23 H24 N4 O2 c1cc(cc(c1....
112 4BTU ic50 = 0.5 nM 6XS C24 H28 Cl2 F N5 O5 S2 CN1CCN(CC1....
113 4BTI ic50 = 0.2 nM 7R9 C26 H32 Cl F2 N5 O6 S2 CN(C)[C@H]....
114 3HPT ic50 = 12 nM YET C23 H28 N6 O3 Cc1cc2cc(c....
115 3ENS ic50 = 8.9 nM ENS C25 H29 Cl N6 O4 COC(=O)C(=....
116 1WU1 ic50 = 18 nM D91 C26 H27 Cl N6 O3 S CC(C)C[C@@....
117 4A7I Ki = 0.002 uM A7I C15 H24 Cl N3 O3 S2 CC(C)N1CCC....
118 1YGC Ki = 0.35 nM 905 C25 H28 F N5 O6 S [H]/N=C(/c....
119 1KLI - BEN C7 H8 N2 [H]/N=C(c1....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: 905; Similar ligands found: 1
No: Ligand ECFP6 Tc MDL keys Tc
1 905 1 1
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1YGC; Ligand: 905; Similar sites found: 22
This union binding pocket(no: 1) in the query (biounit: 1ygc.bio1) has 22 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 2EUG URA 0.01754 0.40684 6.34921
2 1HPG BOC ALA ALA PRO GLU 0.001012 0.45672 9.52381
3 2OUA AES 0.0002632 0.50601 10.6383
4 5JXF ARG ASP 0.004763 0.42065 11.1111
5 5JWI ARG GLU 0.005536 0.40998 11.1111
6 3MMG GLU THR VAL ARG PHE GLN SER ASP 0.001084 0.44383 12.6984
7 1ZBQ NAD 0.01078 0.40659 12.6984
8 4SGA ACE PRO ALA PRO PHE 0.001347 0.41071 17.4603
9 1GJC 130 0.000000009932 0.55065 45.8498
10 1RTF BEN 0.0000000005498 0.57263 46.0317
11 1FIW PBZ 0.0000000005862 0.61623 46.4567
12 1SQA UI1 0.00000002719 0.65859 46.5306
13 1PQ7 ARG 0.0000000009281 0.64904 47.3214
14 2P8O BVA 0.00000003911 0.63731 47.3282
15 1IAU ACE ILE GLU PRO ASJ 0.000002148 0.56766 47.5771
16 5A8Y VBM 0.00000137 0.56222 48.1651
17 1OSS BEN 0.0000000004765 0.58677 48.4305
18 1T32 OHH 0.000003437 0.51338 48.6607
19 2PKA BEN 0.0000003975 0.65347 48.75
20 1ELE 0QN 0.00003701 0.4691 48.75
21 4NFE BEN 0.0000004592 0.49088 49.3671
22 2AIQ BEN 0.000002368 0.48422 49.7836
23 3N7O N7O 0.0000008187 0.51382 50
Pocket No.: 2; Query (leader) PDB : 1YGC; Ligand: 905; Similar sites found: 330
This union binding pocket(no: 2) in the query (biounit: 1ygc.bio2) has 22 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1UO4 PIH 0.000376 0.51568 None
2 3S9K CIT 0.001216 0.50987 None
3 1BTN I3P 0.003883 0.47924 None
4 1UO5 PIH 0.004369 0.46975 None
5 1ECM TSA 0.002351 0.42373 None
6 1ULE GLA GAL NAG 0.01191 0.4221 None
7 2E1A MSE 0.00268 0.42144 None
8 3KPE TM3 0.01344 0.40768 None
9 1B74 DGN 0.005356 0.43887 0.787402
10 4U9W SER GLY ARG GLY LYS NH2 0.014 0.40423 0.966184
11 4R3L COA 0.002536 0.40163 1.15607
12 1AX2 NDG GAL 0.001013 0.44448 1.25523
13 3DCM SAM 0.0005319 0.41438 1.5625
14 1RYD GLC 0.002902 0.43746 1.5748
15 3LST SAH 0.00174 0.41399 1.5748
16 1LYX PGA 0.003597 0.40238 1.6129
17 1RZM E4P 0.001126 0.4633 1.9685
18 1RZM PEP 0.006727 0.41021 1.9685
19 2HW1 ANP 0.001118 0.40576 1.9685
20 4G28 0W8 0.001944 0.42706 2.01342
21 3BY8 MLT 0.001871 0.45309 2.11268
22 2Q1A 2KT 0.002894 0.43752 2.3622
23 1DLJ NAI 0.008251 0.40778 2.3622
24 2RCN GDP 0.004722 0.40674 2.3622
25 1SQ5 ADP 0.004759 0.40213 2.3622
26 1U7Z PMT 0.0006801 0.43087 2.65487
27 1NXJ GLV 0.001742 0.42898 2.73224
28 2Y7P SAL 0.006906 0.40973 2.75229
29 2B7N NTM 0.008177 0.4118 2.75591
30 4N02 FNR 0.007151 0.41169 2.75591
31 1OTH PAO 0.003262 0.40551 2.75591
32 1NF8 BOG 0.01518 0.41089 2.89855
33 1NF8 ISC 0.003603 0.40671 2.89855
34 1XX6 ADP 0.004929 0.40601 3.14136
35 4WBD ADP 0.0009679 0.46634 3.14961
36 4WBD CIT 0.006023 0.43641 3.14961
37 1C0I BE2 0.009279 0.40257 3.14961
38 1C0I FAD 0.009279 0.40257 3.14961
39 3QV9 QV7 0.000935 0.45241 3.1746
40 1ZS6 ADP 0.006406 0.40617 3.1746
41 3PMD 11A 0.001741 0.42368 3.26797
42 3O7B SAH 0.0001915 0.43366 3.27869
43 3BHO B4P 0.01263 0.43552 3.36538
44 4P9Z NMI PTR 02K ASN NH2 0.00242 0.42872 3.4188
45 1XE7 GUN 0.002652 0.46189 3.44828
46 1Y2W NAG 0.01024 0.41299 3.52113
47 3LZW NAP 0.003504 0.42728 3.54331
48 3LZW FAD 0.002006 0.42018 3.54331
49 3F3E LEU 0.003618 0.40982 3.54331
50 3WE0 FAD 0.009092 0.40114 3.54331
51 1J5P NAD 0.002536 0.40385 3.55731
52 2C7G FAD 0.0005193 0.45743 3.93701
53 2C7G ODP 0.0004931 0.45743 3.93701
54 4M5P MLA 0.008434 0.44476 3.93701
55 4M5P 23W 0.02158 0.40958 3.93701
56 4N7C AEF 0.006447 0.42818 3.97727
57 1BGQ RDC 0.00039 0.43023 4
58 1SOW NAD 0.000294 0.44232 4.33071
59 2HGZ PBF 0.002053 0.40231 4.33071
60 2XI7 XI7 0.003396 0.47578 4.34783
61 1A5V Y3 0.0009609 0.4519 4.43038
62 2O66 FLC 0.002874 0.4314 4.44444
63 1Y7P RIP 0.01521 0.41696 4.4843
64 2QLX RM4 0.01651 0.40918 4.62963
65 3NNF AKG 0.01248 0.40912 4.72441
66 1JN2 SFP 0.00003434 0.60925 4.7619
67 3L24 GOA 0.001485 0.47453 4.7619
68 1Y1A GSH 0.005109 0.47289 4.7619
69 3R51 MMA 0.00203 0.46771 4.7619
70 2DWU DGL 0.0004088 0.45435 4.7619
71 2VQ5 LDP 0.004791 0.44898 4.7619
72 2EB5 OXL 0.001722 0.44758 4.7619
73 2XVE FAD 0.001812 0.4405 4.7619
74 2VQ5 HBA 0.007551 0.425 4.7619
75 4RJK PYR 0.01417 0.41844 4.7619
76 2VDJ HSE 0.0186 0.41271 4.7619
77 1O68 KIV 0.007099 0.40923 4.7619
78 1D6H COA 0.005731 0.40856 4.7619
79 3GWT 066 0.00264 0.40744 4.7619
80 1QH9 LAC 0.01399 0.40689 4.7619
81 3RFV NAI 0.002595 0.40351 4.7619
82 1LNX URI 0.005143 0.41507 4.93827
83 1DXY COI 0.01091 0.43099 5.11811
84 3U4C NDP 0.002799 0.40381 5.11811
85 1RYI GOA 0.0152 0.44165 5.51181
86 2C5S AMP 0.009001 0.4002 5.51181
87 2IYG FMN 0.002979 0.40984 5.64516
88 3WUD GLC GAL 0.01879 0.4125 5.88235
89 3P3N AKG 0.005881 0.42376 5.90551
90 2WA4 069 0.002783 0.41096 5.90551
91 3UER BTU 0.003162 0.40886 5.90551
92 3UER TUR 0.003162 0.40886 5.90551
93 1OGD RIP 0.001811 0.43396 6.10687
94 3MAG 3MA 0.005144 0.45606 6.29921
95 3MCT 3MC 0.001932 0.43279 6.29921
96 1OAA OAA 0.00615 0.40742 6.29921
97 1XX4 BAM 0.01013 0.40524 6.29921
98 2B4Q NAP 0.003734 0.40084 6.29921
99 1G8S MET 0.0002914 0.482 6.34921
100 1H16 PYR 0.0031 0.45032 6.34921
101 1H16 DTL 0.006012 0.44402 6.34921
102 3QDY A2G GAL 0.006902 0.43355 6.34921
103 2GWD GLU 0.001369 0.4332 6.34921
104 3QDT A2G GAL 0.007094 0.43298 6.34921
105 3ZPG 5GP 0.01044 0.43196 6.34921
106 1R37 NAD 0.0008196 0.42932 6.34921
107 4COQ SAN 0.004437 0.42923 6.34921
108 3QDY CBS 0.007442 0.42529 6.34921
109 4AF5 CIT 0.005673 0.42446 6.34921
110 1TDF FAD 0.003067 0.42136 6.34921
111 1FIQ FAD 0.001457 0.42043 6.34921
112 1NNS ASP 0.002704 0.41621 6.34921
113 3I0O ADP 0.003516 0.41175 6.34921
114 2F2U M77 0.003827 0.41031 6.34921
115 1KYQ NAD 0.001604 0.40248 6.34921
116 1FIQ MTE 0.003568 0.40153 6.34921
117 1TDF NAP 0.02621 0.40006 6.34921
118 1XIU REA 0.001103 0.41219 6.52174
119 4JWX 1N4 0.004841 0.41617 6.69291
120 1FP2 SAH 0.001835 0.41314 6.69291
121 1QDS PGA 0.0002449 0.45693 6.77291
122 1PR9 NAP 0.002775 0.40925 6.96721
123 3D3W NAP 0.003496 0.40316 6.96721
124 1A59 CIT 0.009414 0.42055 7.08661
125 2QS8 MET 0.003263 0.4015 7.08661
126 2ZSC BTN 0.003599 0.40237 7.0922
127 1YAG ATP 0.001132 0.40931 7.2
128 2WCI GSH 0.003665 0.42685 7.40741
129 1YHM AHD 0.0003482 0.47088 7.48031
130 4EKV BTN 0.005 0.40019 7.54717
131 2DVZ GLU 0.001794 0.42317 7.87402
132 3ZF8 GDP 0.003206 0.41332 7.87402
133 3OIG NAD 0.01065 0.40938 7.87402
134 2V5E SCR 0.003256 0.46649 7.93651
135 2VAR AMP 0.0002131 0.45929 7.93651
136 3LTW HLZ 0.001032 0.45751 7.93651
137 1VDC FAD 0.0004097 0.45494 7.93651
138 3B9Z CO2 0.00127 0.45348 7.93651
139 4WVH ASP HIS ASP ALA HIS ALA 0.001228 0.4351 7.93651
140 4G1V FAD 0.006508 0.43397 7.93651
141 1Q6O LG6 0.0005154 0.42841 7.93651
142 1Y42 TYR 0.003723 0.42092 7.93651
143 2Y6P CTP 0.002692 0.41628 7.93651
144 1C3V PDC 0.008018 0.41217 7.93651
145 2O2C G6Q 0.001477 0.41208 7.93651
146 1KOL NAD 0.003126 0.41098 7.93651
147 4GQB 0XU 0.008141 0.40955 7.93651
148 1GSA ADP 0.007047 0.40872 7.93651
149 1ZFJ IMP 0.02819 0.40823 7.93651
150 1ZJ6 G3D 0.003695 0.4063 7.93651
151 2GDZ NAD 0.003087 0.40372 7.93651
152 1Z45 GAL 0.009897 0.4032 7.93651
153 4Q3F TLA 0.01783 0.40217 7.93651
154 2Q09 DI6 0.008201 0.40183 7.93651
155 2IMP NAI 0.02943 0.40114 7.93651
156 2VAR KDG 0.005146 0.40084 7.93651
157 1MZV AMP 0.006735 0.40071 7.93651
158 1JGS SAL 0.0005835 0.5179 7.97101
159 2WGC SIA GAL BGC 0.02715 0.42583 8.18713
160 3GTD MLI 0.01236 0.40404 8.26772
161 1VQ2 DDN 0.00115 0.41156 8.29016
162 3I6B KDO 0.007022 0.40943 8.33333
163 4B9E FAH 0.0004337 0.48248 8.66142
164 4R33 SAH 0.0009869 0.42515 8.66142
165 4R33 TRP 0.0009869 0.42515 8.66142
166 2F01 BTQ 0.02031 0.40162 8.66142
167 1T57 FMN 0.0002071 0.43211 9.2233
168 1NU4 MLA 0.001915 0.48948 9.27835
169 1YOA FMN 0.002095 0.48734 9.43396
170 4E28 9MZ 0.001056 0.45707 9.44882
171 4E28 0MZ 0.001837 0.43978 9.44882
172 1Q3Q ANP 0.001882 0.4353 9.44882
173 3TKA CTN 0.000641 0.54106 9.52381
174 2YIV YIV 0.0001031 0.52147 9.52381
175 1WRA PC 0.0008148 0.46981 9.52381
176 1GPJ CIT 0.0007111 0.46472 9.52381
177 4JCA CIT 0.005803 0.45331 9.52381
178 3SCH TB6 0.001358 0.45219 9.52381
179 1SC3 MLI 0.003241 0.44939 9.52381
180 4O8A 2OP 0.008478 0.43651 9.52381
181 2YIV NBN 0.004472 0.43555 9.52381
182 2FR6 CTN 0.0002027 0.43283 9.52381
183 3TFC PEP 0.002123 0.43108 9.52381
184 2Z9V PXM 0.002418 0.42874 9.52381
185 3GJB AKG 0.002247 0.42453 9.52381
186 1Q11 TYE 0.003084 0.42433 9.52381
187 1RY2 AMP 0.0005216 0.42421 9.52381
188 1UXG FUM 0.001596 0.42377 9.52381
189 1UXG NAD 0.001596 0.42377 9.52381
190 4C2G ALA ALA ALA ALA 0.002552 0.42229 9.52381
191 4C6F DOR 0.002213 0.41961 9.52381
192 4C6F NCD 0.002213 0.41961 9.52381
193 1I2B USQ 0.005084 0.41886 9.52381
194 1I2B UPG 0.005084 0.41886 9.52381
195 1I2B NAD 0.005084 0.41886 9.52381
196 2BLE 5GP 0.00612 0.41867 9.52381
197 1E7S NAP 0.001445 0.41797 9.52381
198 3SJ0 DXC 0.01083 0.41771 9.52381
199 4LO6 SIA GAL 0.01268 0.41758 9.52381
200 3DX5 DHB 0.00273 0.41605 9.52381
201 4M51 BEZ 0.01653 0.41521 9.52381
202 4KGM ATP 0.003285 0.40823 9.52381
203 1JUV NDP 0.00197 0.40612 9.52381
204 4A6D SAM 0.0009562 0.40601 9.52381
205 2NLI LAC 0.009486 0.40549 9.52381
206 2NLI FMN 0.009486 0.40549 9.52381
207 1AUX AGS 0.001838 0.40448 9.52381
208 3ZGE ASP 0.02805 0.40403 9.52381
209 4P4T GDP 0.001577 0.40273 9.52381
210 2J7T 274 0.003048 0.40253 9.52381
211 1E4E PHY 0.002964 0.40126 9.52381
212 1WDA BAG 0.009046 0.40011 9.52381
213 4F8L GAL 0.0007553 0.51173 9.65517
214 1O9U ADZ 0.002665 0.46178 9.84252
215 4KCT PYR 0.004621 0.4119 10.6299
216 4KCT FDP 0.002957 0.40997 10.6299
217 2ZWS PLM 0.00008199 0.56479 11.1111
218 1SS4 GSH 0.0007563 0.51917 11.1111
219 1SS4 CIT 0.002129 0.51716 11.1111
220 1T0S BML 0.001908 0.46048 11.1111
221 1QF5 RPL 0.0007115 0.44598 11.1111
222 1QF5 GDP 0.0007115 0.44598 11.1111
223 2OWZ CIT 0.002017 0.44452 11.1111
224 2BZ1 TAU 0.01293 0.44372 11.1111
225 2IZ1 ATR 0.002296 0.44201 11.1111
226 2NCD ADP 0.00222 0.43623 11.1111
227 4HZO COA 0.001933 0.43279 11.1111
228 3A1I UNU 0.00139 0.4275 11.1111
229 2HFK E4H 0.002956 0.4251 11.1111
230 4DYO SD4 0.002362 0.42365 11.1111
231 1V35 NAI 0.002065 0.42291 11.1111
232 1GJW GLC 0.01011 0.4191 11.1111
233 3KJQ B94 0.001879 0.41743 11.1111
234 5EQU AKG 0.01934 0.41189 11.1111
235 2Q8M AMP 0.00287 0.41046 11.1111
236 1YOE RIB 0.00197 0.4091 11.1111
237 2JBH 5GP 0.005596 0.40854 11.1111
238 2PT9 S4M 0.00171 0.40665 11.1111
239 2WMO GTP 0.002793 0.40643 11.1111
240 3PLN U5P 0.008678 0.40559 11.1111
241 4EPL JAI 0.002684 0.4028 11.1111
242 4CMF PXG 0.01321 0.40005 11.1111
243 1H2M OGA 0.004294 0.42987 11.5385
244 2JFV FLC 0.003072 0.43636 11.811
245 4DQ2 BTX 0.002817 0.40372 11.811
246 3EW2 BTN 0.001459 0.43209 11.8519
247 1PTR PRB 0.00007703 0.51721 12
248 3PNA CMP 0.000691 0.44516 12.3377
249 1PEA ACM 0.0004254 0.49185 12.6984
250 1I9G SAM 0.000856 0.44104 12.6984
251 3CEV ARG 0.001172 0.43592 12.6984
252 3SHR CMP 0.001227 0.42962 12.6984
253 4QVH FLC 0.03894 0.41754 12.6984
254 1P72 THM 0.004766 0.41645 12.6984
255 2DTJ THR 0.002706 0.41619 12.6984
256 2C31 TZD 0.01241 0.41353 12.6984
257 2C31 ADP 0.01201 0.41353 12.6984
258 4GO7 THR 0.003731 0.41074 12.6984
259 1KTC NGA 0.006752 0.41014 12.6984
260 4OB6 S2T 0.001715 0.40976 12.6984
261 2CE7 ADP 0.002309 0.40946 12.6984
262 4PLG NAI 0.003756 0.40923 12.6984
263 4PLG OXM 0.003756 0.40923 12.6984
264 4BAS GNP 0.0009554 0.40803 12.6984
265 1UOU CMU 0.003698 0.40194 12.6984
266 2P69 PLP 0.004238 0.42413 12.9921
267 1JQ5 NAD 0.03102 0.41528 12.9921
268 3T2W BTN 0.003348 0.41258 13.1148
269 2BOI MFU 0.003284 0.4232 13.2743
270 4DN8 BMA 0.009407 0.41463 13.4615
271 2YLD CMO 0.007718 0.41848 14.1732
272 2Q3M MLA 0.0004302 0.50153 14.2857
273 1Z42 HBA 0.004601 0.47026 14.2857
274 9LDT OXM 0.003767 0.46317 14.2857
275 4JEJ 1GP 0.0001303 0.46131 14.2857
276 3SQG COM 0.005932 0.4528 14.2857
277 3Q9T FAY 0.000289 0.45061 14.2857
278 9LDB NAD 0.000297 0.44069 14.2857
279 3FPZ AHZ 0.005388 0.43073 14.2857
280 1FBL HTA 0.001856 0.42259 14.2857
281 1I1Q TRP 0.005234 0.40971 14.2857
282 1QD0 RR6 0.00339 0.40772 14.2857
283 3W8S GSH 0.01094 0.40633 14.2857
284 1PX8 XYP 0.01247 0.40388 14.2857
285 2ALG HP6 0.0016 0.40061 14.2857
286 2ALG DAO 0.0016 0.40061 14.2857
287 2W8Q SIN 0.02074 0.40455 15.3543
288 2Q8H TF4 0.00198 0.46826 15.873
289 4B16 NAG 0.004472 0.45925 15.873
290 3RK0 AMP 0.0002004 0.45424 15.873
291 3U1T MLI 0.001928 0.45249 15.873
292 2OFE NAG 0.003418 0.43429 15.873
293 3R35 4CO 0.0004674 0.43379 15.873
294 1TUV VK3 0.01301 0.42713 15.873
295 3GEG NAD 0.0006103 0.42519 15.873
296 1LTH NAD 0.0062 0.41845 15.873
297 2XK9 XK9 0.001962 0.41584 15.873
298 4JLV ADP 0.03942 0.4129 15.873
299 1I0Z OXM 0.02886 0.40961 15.873
300 3DG6 MUC 0.002646 0.40729 15.873
301 2OFD NGA 0.01748 0.40255 15.873
302 2Q37 3AL 0.003262 0.42903 16.0221
303 1YBH P22 0.0007485 0.43799 17.4603
304 4K5S FAD 0.0007636 0.42909 17.4603
305 1DL7 NCH 0.03767 0.41787 17.4603
306 2XDQ MGX 0.02972 0.40896 17.4603
307 4K5S PM0 0.01249 0.40019 17.4603
308 3QP4 HL0 0.002447 0.40424 17.5824
309 4USS GSH 0.0003518 0.46359 19.0476
310 3L6R MLI 0.004239 0.43663 19.0476
311 1NML CIT 0.003614 0.42146 19.0476
312 1C1L GAL BGC 0.01193 0.41577 19.0476
313 1X8X TYR 0.003366 0.41249 19.0476
314 1QR0 COA 0.006925 0.40023 19.0476
315 3CQD ATP 0.001099 0.42848 20.6349
316 3KYF 5GP 5GP 0.001473 0.42651 20.6349
317 3PFG TLO 0.00699 0.40254 20.6349
318 3PFG SAM 0.00699 0.40254 20.6349
319 3RF4 FUN 0.002415 0.42876 21.5517
320 1F1V DHY 0.001242 0.43491 22.2222
321 4W6Z ETF 0.03044 0.40843 22.2222
322 3F81 STT 0.003277 0.45727 25.3968
323 4Q3R XA2 0.00183 0.40564 25.3968
324 1DSS NAD 0.001233 0.41148 26.9841
325 3DDC GNP 0.002193 0.40296 28.5714
326 1H2K OGA 0.005176 0.42624 29.2683
327 1Y75 NAG 0.003231 0.41817 30.1587
328 4K30 NLG 0.01164 0.40025 34.9206
329 4B7E OGA 0.01531 0.40001 41.1765
330 1JAC AMG 0.001586 0.48288 45
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