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Receptor
PDB id Resolution Class Description Source Keywords
1YKD 1.9 Å EC: 4.6.1.1 CRYSTAL STRUCTURE OF THE TANDEM GAF DOMAINS FROM A CYANOBACT ADENYLYL CYCLASE: NOVEL MODES OF LIGAND-BINDING AND DIMERIZ ANABAENA SP. GAF DOMAIN BOUND CYCLIC AMP LIGAND LYASE
Ref.: CRYSTAL STRUCTURE OF THE TANDEM GAF DOMAINS FROM A CYANOBACTERIAL ADENYLYL CYCLASE: MODES OF LIGAND BI DIMERIZATION PROC.NATL.ACAD.SCI.USA V. 102 3082 2005
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
CMP A:501;
A:502;
B:503;
B:504;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
submit data
329.206 C10 H12 N5 O6 P c1nc(...
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1YKD 1.9 Å EC: 4.6.1.1 CRYSTAL STRUCTURE OF THE TANDEM GAF DOMAINS FROM A CYANOBACT ADENYLYL CYCLASE: NOVEL MODES OF LIGAND-BINDING AND DIMERIZ ANABAENA SP. GAF DOMAIN BOUND CYCLIC AMP LIGAND LYASE
Ref.: CRYSTAL STRUCTURE OF THE TANDEM GAF DOMAINS FROM A CYANOBACTERIAL ADENYLYL CYCLASE: MODES OF LIGAND BI DIMERIZATION PROC.NATL.ACAD.SCI.USA V. 102 3082 2005
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 9 families.
1 1YKD - CMP C10 H12 N5 O6 P c1nc(c2c(n....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 9 families.
1 1YKD - CMP C10 H12 N5 O6 P c1nc(c2c(n....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 8 families.
1 1YKD - CMP C10 H12 N5 O6 P c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: CMP; Similar ligands found: 93
No: Ligand ECFP6 Tc MDL keys Tc
1 2BA 1 0.984848
2 CMP 1 1
3 RP1 0.757143 0.928571
4 SP1 0.757143 0.928571
5 1YD 0.727273 0.902778
6 4BW 0.727273 0.902778
7 1SY 0.653061 0.902778
8 1OR 0.635294 0.807692
9 4UR 0.626263 0.902778
10 7CH 0.580247 0.984615
11 6SX 0.573171 0.953846
12 6SZ 0.559524 0.984848
13 N6R 0.535354 0.914286
14 N6S 0.535354 0.914286
15 PCG 0.534091 0.888889
16 35G 0.534091 0.888889
17 C2E 0.534091 0.902778
18 1YC 0.53 0.875
19 Y3J 0.506667 0.753623
20 XYA 0.5 0.826087
21 5CD 0.5 0.811594
22 ACK 0.5 0.897059
23 RAB 0.5 0.826087
24 ADN 0.5 0.826087
25 6SW 0.494382 0.9
26 5AD 0.493151 0.776119
27 5N5 0.486842 0.8
28 75G 0.483146 0.890411
29 A4D 0.480519 0.8
30 M2T 0.475 0.736842
31 MTA 0.469136 0.777778
32 CC5 0.466667 0.850746
33 EP4 0.4625 0.756757
34 DTA 0.45679 0.816901
35 QQX 0.452381 0.835616
36 LMS 0.447059 0.7875
37 AMP 0.447059 0.927536
38 QQY 0.447059 0.847222
39 A 0.447059 0.927536
40 3DH 0.440476 0.777778
41 3AM 0.435294 0.913043
42 A2D 0.431818 0.928571
43 J7C 0.431818 0.75
44 ABM 0.431818 0.901408
45 ZAS 0.430233 0.77027
46 7D7 0.428571 0.771429
47 S4M 0.426966 0.666667
48 SRA 0.425287 0.876712
49 6RE 0.425287 0.74026
50 3AD 0.425 0.838235
51 2AM 0.423529 0.9
52 BA3 0.422222 0.928571
53 A12 0.422222 0.864865
54 AP2 0.422222 0.864865
55 MAO 0.422222 0.740741
56 DSH 0.420455 0.727273
57 NEC 0.420455 0.726027
58 AOC 0.420455 0.802817
59 A3G 0.420455 0.780822
60 SFG 0.419355 0.753425
61 6JR 0.419048 0.927536
62 ADP 0.417582 0.901408
63 AP5 0.417582 0.928571
64 5AS 0.417582 0.741176
65 B4P 0.417582 0.928571
66 A3N 0.41573 0.767123
67 APC 0.414894 0.864865
68 AN2 0.413043 0.888889
69 SON 0.413043 0.864865
70 AT4 0.413043 0.864865
71 EEM 0.412371 0.691358
72 GJV 0.411111 0.730769
73 GGZ 0.41 0.78481
74 OVE 0.409091 0.863014
75 M33 0.408602 0.888889
76 ADX 0.408602 0.810127
77 AU1 0.408602 0.876712
78 CA0 0.408602 0.876712
79 A3P 0.406593 0.927536
80 5X8 0.404255 0.767123
81 ATP 0.404255 0.901408
82 ACP 0.404255 0.876712
83 HEJ 0.404255 0.901408
84 50T 0.404255 0.888889
85 ADP VO4 0.40404 0.888889
86 VO4 ADP 0.40404 0.888889
87 SAM 0.402062 0.691358
88 0UM 0.401961 0.7
89 AR6 0.4 0.901408
90 AQP 0.4 0.901408
91 5FA 0.4 0.901408
92 APR 0.4 0.901408
93 PRX 0.4 0.876712
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1YKD; Ligand: CMP; Similar sites found with APoc: 426
This union binding pocket(no: 1) in the query (biounit: 1ykd.bio1) has 20 residues
No: Leader PDB Ligand Sequence Similarity
1 3GWL FAD None
2 2VWA PTY None
3 4WG0 CHD None
4 4ZGM 32M 0.819672
5 4XBA GMP 1
6 5MDH MAK 1.2012
7 5BU2 AMP 1.25628
8 1OUK 084 1.36612
9 4LOO SB4 1.38504
10 5HV7 RBL 1.50754
11 1GZ4 FUM 1.50754
12 4RD0 GDP 1.50754
13 5Y79 3PG 1.51976
14 4LSJ LSJ 1.55039
15 1M2Z DEX 1.55642
16 1IXI 2HP 1.55763
17 4P6X HCY 1.56863
18 4URX FK1 1.62162
19 3VHE 42Q 1.67131
20 5DEY 59T 1.6835
21 3I4X DST 1.75879
22 5IUY BOG 1.75879
23 3LDW IPE 1.76768
24 1TQP ATP 1.77305
25 1Y7P RIP 1.79372
26 2OS2 OGA 1.83727
27 5ISY NAD 1.9305
28 4JZX 476 1.9337
29 1VJY 460 1.9802
30 3KP6 SAL 1.98676
31 2Q1H AS4 2
32 1GQG DCD 2
33 3CEV ARG 2.00669
34 1S5O 152 2.01005
35 6FXR AKG 2.01005
36 4DO1 ANN 2.01005
37 1AUA BOG 2.02703
38 5FIT AP2 2.04082
39 3LA3 2FT 2.05761
40 5NTP 98E 2.10084
41 5TVI MYR 2.17391
42 5M37 9SZ 2.17391
43 5EXA 5SO 2.17391
44 3PN1 IVH 2.20126
45 4TWP AXI 2.21402
46 5ZMY TAR 2.2293
47 5X20 AOT 2.24359
48 5W0N UPU 2.26131
49 4J6C STR 2.26131
50 5XWV 8H6 2.26131
51 3HYW DCQ 2.26131
52 5FR0 SIZ 2.26131
53 4JD3 PLM 2.26629
54 4JD3 COA 2.26629
55 3NW7 LGV 2.28013
56 2Y7P SAL 2.29358
57 1OC2 TDX 2.29885
58 1OC2 NAD 2.29885
59 4UDK BMA 2.30548
60 5YU3 NAD 2.32558
61 5YU3 PRO 2.32558
62 4L9Z OXL 2.35988
63 3G58 988 2.3622
64 2UW1 GVM 2.36686
65 3V78 ET 2.40385
66 3K4Z CBI 2.42215
67 3Q60 ATP 2.42588
68 1P1M MET 2.51256
69 4QHP 32Q 2.51256
70 2IUW AKG 2.52101
71 3E85 BSU 2.53165
72 6FOF LAT 2.55102
73 5YJS SAL 2.5641
74 4YGF AZM 2.5641
75 5MOB A8S 2.58621
76 5NM7 GLY 2.63158
77 2Z7I 742 2.64706
78 1R6D DAU 2.67062
79 4BVA T3 2.68657
80 4J4H NAI 2.7027
81 4XT8 TMQ 2.71318
82 2G30 ALA ALA PHE 2.71318
83 5HCV 60R 2.72374
84 1YUC EPH 2.7451
85 1YFS ALA 2.76382
86 4ZW3 4S9 2.76382
87 5K8P 6R8 2.76382
88 2A3I C0R 2.7668
89 5A5W GUO 2.7668
90 4E2J MOF 2.8
91 3GN8 DEX 2.81124
92 1DMY AZM 2.82258
93 5UFS 1TA 2.82258
94 1ZDU P3A 2.85714
95 2HZQ STR 2.87356
96 5JKG 6LF 2.89389
97 5JIB OIA 2.96736
98 1XL8 152 3.01508
99 3VRY B43 3.01508
100 1OFL NGK GCD 3.01508
101 1Q19 SSC 3.01508
102 3A51 VDY 3.01508
103 1M5B BN1 3.04183
104 5BVE 4VG 3.04709
105 2Z9V PXM 3.06122
106 2YMZ LAT 3.07692
107 1XXR MAN 3.10559
108 2AX9 BHM 3.125
109 3VV1 GAL FUC 3.125
110 1XQP 8HG 3.125
111 3GM5 CIT 3.14465
112 6MPT C30 3.14685
113 4FBL SPD 3.20285
114 1WS1 BB2 3.20513
115 2GBB CIT 3.20513
116 3D91 REM 3.22581
117 4G7A AZM 3.22581
118 3ZGJ RMN 3.2345
119 5D9G GLU ASN LEU TYR PHE GLN 3.25203
120 5CX6 CDP 3.26633
121 2XFH CL6 3.26633
122 5I49 2KH 3.26633
123 1EM6 NBG 3.26633
124 2RCU BUJ 3.26633
125 2ZXG S23 3.26633
126 5A1S FLC 3.26633
127 3G5K BB2 3.27869
128 5DY5 5GR 3.28947
129 1ZPT FAD 3.28947
130 2X34 UQ8 3.31492
131 2X32 OTP 3.35196
132 2XMY CDK 3.3557
133 5NFB 8VT 3.40909
134 2Y6O 1N1 3.43643
135 4TS1 TYR 3.44828
136 1QY1 PRZ 3.44828
137 6ALW BNV 3.47222
138 6ALW BMJ 3.47222
139 3VQ2 LP4 LP5 MYR DAO 3.47222
140 2ET1 GLV 3.48259
141 1ZPD CIT 3.51759
142 2XXP DSL 3.51759
143 3DTU DXC 3.51759
144 5ZKC 3C0 3.51759
145 4MRP GSH 3.51759
146 5LX9 OLB 3.52113
147 6D61 4AA 3.58974
148 4DXJ 0M9 3.59116
149 1YHM AHD 3.59116
150 4RKK GLC GLC GLC GLC GLC GLC 3.61446
151 5N7O 69Y 3.61991
152 4I90 CHT 3.63036
153 2XVD AS6 3.64238
154 3W21 AKG 3.663
155 4G31 0WH 3.67893
156 1RQJ RIS 3.67893
157 2GJ5 VD3 3.7037
158 1DTL BEP 3.72671
159 3FW3 ETS 3.7594
160 4DV8 0LX 3.76884
161 4GBD MCF 3.76884
162 2YB9 HA0 3.76884
163 5OLK DTP 3.76884
164 3ROE THM 3.77358
165 3ZJX BOG 3.80623
166 4N9I PCG 3.80952
167 5V13 JH3 3.81944
168 3PUA OGA 3.82653
169 1ELI PYC 3.85604
170 4R78 AMP 3.8835
171 2VFK AMP 3.90244
172 1OF4 BMA BMA BMA BMA BMA 3.91061
173 5L7G 6QE 3.93443
174 6BYM HC3 3.94089
175 5UWA 8ND 3.94089
176 2VQ5 HBA 3.9801
177 5C1M CLR 4
178 3ML1 MGD 4.0201
179 1RM0 NAI 4.0201
180 1N20 3AG 4.0201
181 5KOD IAC 4.0201
182 4B3J COA 4.0201
183 1Q7E MET 4.0201
184 4MN7 SME 4.02685
185 1ZZ7 S0H 4.0404
186 5WSY 7UC 4.04624
187 5K4W THR 4.04984
188 4Q9M 2ZW 4.06504
189 5O9W AKG 4.08719
190 4OCX MT1 4.16667
191 1EKX PAL 4.18006
192 4J7Q B7N 4.2042
193 4LA7 A1O 4.22961
194 1SR7 MOF 4.2471
195 4RHP PEF 4.25532
196 4OAR 2S0 4.26357
197 3KO0 TFP 4.27136
198 4NOS H4B 4.27136
199 1ME8 RVP 4.27136
200 5OF1 SAL 4.28571
201 5G5W R8C 4.28571
202 4AZC NGW 4.29864
203 1U70 NDP 4.30108
204 1U70 MTX 4.30108
205 4MGD 27N 4.31373
206 4MGB XDH 4.31373
207 5IXH OTP 4.34783
208 5AAV GW5 4.36508
209 2BJ4 OHT 4.36508
210 4TV1 36M 4.38247
211 1M1B SPV 4.40678
212 4UDB CV7 4.41176
213 3WUD GLC GAL 4.41176
214 4AVV CD 4.41176
215 1M13 HYF 4.43038
216 2QE4 JJ3 4.43548
217 1I06 TZL 4.44444
218 1S17 GNR 4.44444
219 1U25 IHS 4.45104
220 3ET3 ET1 4.45205
221 6AYH C3G 4.47761
222 5XXH E0D 4.51128
223 5H9Q TD2 4.51613
224 4LIT AKG 4.52261
225 6FCX FAD 4.52261
226 6AYI C3G 4.52261
227 2YIV YIV 4.52261
228 5Y1G AKB 4.52261
229 3A76 SPD 4.54545
230 5GLT BGC GAL NAG GAL 4.57746
231 2HZL PYR 4.65753
232 4DR9 BB2 4.6875
233 3UXL CFI 4.69974
234 3PP0 03Q 4.73373
235 1ZS6 ADP 4.73373
236 3KRO DST 4.74576
237 3KRO IPE 4.74576
238 4JHG ZEA 4.7619
239 4RF7 ARG 4.77387
240 4WOE ADP 4.77387
241 2X5W K2B 4.77387
242 3RUG DB6 4.77387
243 5IF4 6AK 4.77387
244 2GC0 PAN 4.78723
245 4ASE AV9 4.81586
246 5FH7 5XL 4.83871
247 1Y7I SAL 4.85075
248 4DOO DAO 4.87805
249 4TWL ASC 4.87805
250 1GVE CIT 4.89297
251 5YSQ INS 4.8951
252 5HCN DAO 4.98084
253 3OBT SLB 5.02513
254 2XIQ MLC 5.02513
255 4V1T ADP 5.02513
256 1JGS SAL 5.07246
257 1OFZ FUC 5.12821
258 1DKF BMS 5.15021
259 6GNO XDI 5.18518
260 1A78 TDG 5.22388
261 3TDC 0EU 5.27638
262 2E2R 2OH 5.27638
263 4BXF AKG 5.27638
264 2I74 MAN MAN MAN MAN 5.29101
265 4JX1 CAM 5.30973
266 4JX1 CAH 5.30973
267 3D72 FAD 5.36913
268 4AG8 AXI 5.37975
269 5G1N PAL 5.41401
270 2ALG DAO 5.43478
271 2ALG HP6 5.43478
272 5KAU RHQ 5.45455
273 4BIX ADP 5.52764
274 1T27 PCW 5.53506
275 2A1L PCW 5.55556
276 3DFR MTX 5.55556
277 2C29 NAP 5.63798
278 2C29 DQH 5.63798
279 2QQC AG2 5.66038
280 5IVX ARG GLY PRO GLY ARG ALA PHE VAL THR ILE 5.6701
281 5K21 6QF 5.67376
282 4C1K PEP 5.72519
283 3GL0 HXX 5.73066
284 2A2C ADP 5.77889
285 2A2C NG1 5.77889
286 3ZPG 5GP 5.77889
287 6BLD DXJ 5.77889
288 4OCT AKG 5.77889
289 3BZ3 YAM 5.7971
290 5CHR 4NC 5.83942
291 4YJK URA 5.95238
292 3B9Z CO2 6.03015
293 6GN6 MAL 6.03015
294 4X5S AZM 6.03448
295 6FS0 E4W 6.04651
296 5C9J DAO 6.06061
297 1Q3A NGH 6.06061
298 4WVO 3UZ 6.07735
299 3VMG 9CA 6.08696
300 6A5Y 9CR 6.14035
301 5MWE TCE 6.17284
302 5V4R MGT 6.17284
303 4R6W PC 6.20155
304 2I0G I0G 6.22568
305 5W1E PHB 6.27376
306 1H70 CIR 6.27451
307 2Q0D ATP 6.28141
308 4F7E 0SH 6.36042
309 3RLF MAL 6.41892
310 3A16 PXO 6.43432
311 5VNF VAL THR SER VAL VAL 6.53266
312 2HHP FLC 6.53266
313 1XMY ROL 6.53266
314 1M6P M6P 6.57895
315 1R6N 434 6.63507
316 5W4W 9WG 6.64653
317 4KBA 1QM 6.64653
318 2YJD YJD 6.66667
319 3QUZ QUV 6.66667
320 4COQ SAN 6.88259
321 5TZO 7V7 6.91489
322 1GT4 UNA 6.91824
323 4OTH DRN 7.03812
324 1KGI T4A 7.08661
325 4RYV ZEA 7.09677
326 5XVG 8FX 7.16724
327 5AIG VPR 7.2
328 5N8V KZZ 7.24638
329 3WMX THR 7.26257
330 3P9T TCL 7.30594
331 1ULE GLA GAL NAG 7.33333
332 3ZO7 K6H 7.44681
333 3M3E GAL A2G NPO 7.45342
334 4QYN RTL 7.5188
335 5OD2 GLC 7.53769
336 3TL1 JRO 7.54717
337 1X0P FAD 7.69231
338 1UNB AKG 7.71704
339 1UNB PN1 7.71704
340 3WV6 GAL BGC 7.77027
341 3WV6 GAL GLC 7.77027
342 1XSE NDP 7.78894
343 1CZA ADP 7.78894
344 3DZT EAH 8.0402
345 5XEG AKG 8.22511
346 2OVD DAO 8.24176
347 5CKS GAL 8.26211
348 1J78 VDY 8.29146
349 4WGF HX2 8.29268
350 3VRV YSD 8.48709
351 2ZCQ B65 8.53242
352 5E58 CPZ 8.54271
353 1F9V ADP 8.64553
354 2BCG GER 8.73786
355 3R9V DXC 8.74126
356 4OGQ 7PH 8.75
357 2XKO AKG 8.98876
358 3AB4 THR 8.98876
359 3G5N PB2 9.04523
360 2UXI G50 9.04762
361 1ECM TSA 9.17431
362 1T0S BML 9.30233
363 1C1L GAL BGC 9.48905
364 4L4J NAG NAG BMA MAN NAG 9.50226
365 3JRS A8S 9.61539
366 5UGW GSH 9.71429
367 3O01 DXC 9.74026
368 2E3N 6CM 9.80392
369 3KDJ A8S 9.90099
370 5UR6 8KM 9.94475
371 4YEE 4CQ 10
372 4R3U 3KK 10.1266
373 4R3U 3HC 10.1266
374 5N17 8FK 10.1449
375 3UB7 ACM 10.4972
376 4AF5 CIT 10.5263
377 3JU6 ANP 10.5405
378 1ZED PNP 10.5528
379 6CAY ERG 10.6509
380 3E8T UQ8 11.3636
381 2ZFZ ARG 11.3924
382 4OIT MAN 11.5044
383 5L8N 6RQ 11.7188
384 2WCV FUC 12.1429
385 5W97 CHD 12.3348
386 5Z84 CHD 12.3348
387 5ZCO CHD 12.3348
388 1SW1 PBE 12.7273
389 4GLW 0XT 12.7869
390 5Y02 MXN 13.0841
391 1MID LAP 13.1868
392 2YKL NLD 13.6792
393 1WW5 SGA BGC 13.75
394 4MA6 28E 14.0127
395 2Y69 CHD 14.2857
396 6BVM EBV 14.3713
397 6BVK EAV 14.3713
398 6BVI EC4 14.3713
399 6BVJ EAS 14.3713
400 6BVL EBY 14.3713
401 6D56 FVM 14.3713
402 6D5G FVD 14.3713
403 6D55 FWA 14.3713
404 3MB3 MB3 14.8148
405 3EM0 CHD 15.2174
406 2Y2B AH0 15.508
407 5DG2 GAL GLC 15.5556
408 1KJ1 MAN 15.5963
409 5N18 8HZ 15.5963
410 3MTX PGT 15.894
411 1NU4 MLA 16.4948
412 4R38 RBF 17.1429
413 3MMH SME 17.3653
414 2IDO TMP 19.2771
415 3NV3 GAL NAG MAN 19.5652
416 1DZK PRZ 19.7452
417 5W7B MYR 19.8582
418 6FA4 D1W 20.2312
419 3NMV PYV 20.7865
420 5M36 9SZ 21.0526
421 3N7S 3N7 23.9583
422 5NNT DPV 29.7297
423 5W10 CMP 37.9487
424 3SAO DBH 38.125
425 3SAO NKN 38.125
426 2ZMF CMP 48.1481
Pocket No.: 2; Query (leader) PDB : 1YKD; Ligand: CMP; Similar sites found with APoc: 80
This union binding pocket(no: 2) in the query (biounit: 1ykd.bio1) has 20 residues
No: Leader PDB Ligand Sequence Similarity
1 4XMF HSM 1.08696
2 2ABS ACP 1.56658
3 3BQD DAY 1.56863
4 5JNN 6LM 1.57895
5 1EU1 MGD 1.75879
6 3CV2 COA 1.75879
7 4QO5 NAG 2.01005
8 5IH9 6BF 2.08955
9 6F6D AKG 2.26131
10 6F8A HIS 2.26131
11 4FFG 0U8 2.51256
12 1N6B DMZ 2.51256
13 2FCU AKG 2.55591
14 1RJW ETF 2.65487
15 4J4H 1J1 2.7027
16 2FDW D3G 2.73109
17 4J36 1HR 2.76382
18 5EOB 5QQ 2.82132
19 3A4V PYR 2.83912
20 3A4V NAD 2.83912
21 2DSA GSH 2.95567
22 4WW8 VD9 3.04183
23 6GQM F8H 3.04878
24 3KFF XBT 3.08642
25 3KFF ZBT 3.08642
26 6CI9 F3V 3.0888
27 1AV5 AP2 3.1746
28 4U0I 0LI 3.1746
29 5EW9 5VC 3.32103
30 4QCK ASD 3.62694
31 4B1L FRU 3.63636
32 1OIJ AKG 3.65448
33 3QRY DMJ 3.76884
34 3AVR OGA 3.76884
35 4CU1 H4B 3.76884
36 1W2D ADP 3.77358
37 1K12 FUC 3.79747
38 5HA0 LTD 3.84615
39 6A0S NDP 4.21687
40 4B7P 9UN 4.34783
41 1QIN GIP 4.37158
42 3BRN SRO 4.4586
43 2G2Y MLI 4.54545
44 5TO8 7FM 4.60993
45 4OKZ 3E9 4.65753
46 3L5R 47X 4.91803
47 1KEW NAD 5.54017
48 3UVD MB3 5.64516
49 3UP3 XCA 5.76132
50 4QM9 CYS 5.78035
51 4K2G 1OQ 5.88235
52 3N1S 5GP 5.88235
53 5EPA AKG 6.09319
54 3T50 FMN 6.25
55 3A70 NPO 6.28141
56 5OES ADP 6.53266
57 3G08 FEE 6.66667
58 1YP0 PEF 6.69456
59 3RV5 DXC 6.74157
60 6HDT BTN 6.76692
61 2V3V MGD 6.78392
62 5TG5 JW8 7.34694
63 4RFR RHN 7.38916
64 2XK9 XK9 7.76398
65 5YEE LAB 8.08823
66 5JSP DQY 8.45771
67 1OW4 2AN 8.52713
68 3JQM GTP 8.9172
69 5C2H 4PX 9.11602
70 4J7U NAP 9.72222
71 4J7U YTZ 9.72222
72 1Y9Q MED 9.89583
73 4GNC ASO 10.0334
74 4PIV NDP 10.0503
75 1NX4 AKG 10.989
76 2D6M LBT 11.3208
77 4CUB GAL NAG 12.0219
78 5T2Z 017 14.1414
79 6EIZ FOH 18.75
80 2AGC DAO 19.1358
Pocket No.: 3; Query (leader) PDB : 1YKD; Ligand: CMP; Similar sites found with APoc: 158
This union binding pocket(no: 3) in the query (biounit: 1ykd.bio1) has 18 residues
No: Leader PDB Ligand Sequence Similarity
1 3QWI NAP 1.11111
2 2OVW CBI 1.50754
3 2GPT TLA 1.50754
4 4NV7 COA 1.60256
5 3SLS 77D 1.64474
6 4HAP CBI 1.75879
7 5MZI FYK 2.01005
8 5MZI FAD 2.01005
9 6E08 NAP 2.01005
10 4N14 WR7 2.01005
11 1JV1 UD1 2.01005
12 3FW9 SLX 2.01005
13 4HNN LYS 2.02312
14 2CI5 HCS 2.11268
15 5NLD LBT 2.15827
16 4D4U FUC 2.22222
17 4MZU TYD 2.24359
18 1OLM VTQ 2.26131
19 4U03 GTP 2.26131
20 4JN6 OXL 2.31214
21 4WHZ 3NL 2.33766
22 4B5W PYR 2.34375
23 4L9Z COA 2.35988
24 3I8T LBT 2.43902
25 3B1Q NOS 2.45399
26 3E7O 35F 2.5
27 1EWF PC1 2.51256
28 4XV1 904 2.51256
29 4FFG LBS 2.51256
30 6BK3 B2S 2.76382
31 4J36 FAD 2.76382
32 1GP6 QUE 2.80899
33 1GP6 DH2 2.80899
34 1GP6 SIN 2.80899
35 5GWT NAD 2.8777
36 1IS3 LAT 2.96296
37 3OYW TDG 2.98507
38 2PFY PCA 2.99003
39 3ZXE PGZ 3.00752
40 1ODM ASV 3.02115
41 1U7T TDT 3.06513
42 6CI9 NAP 3.0888
43 3E8N ATP 3.22581
44 3E8N VRA 3.22581
45 4OMJ 2TX 3.23741
46 3NUG NAD 3.23887
47 3E2M E2M 3.24324
48 3EKK GS2 3.25733
49 3WXL ADP 3.26633
50 3FXU TSU 3.27869
51 4L2I NAD 3.42205
52 3PFG TLO 3.42205
53 3PFG SAM 3.42205
54 3ZDS HQ9 3.51759
55 3ZDS HMQ 3.51759
56 3ZDS OMD 3.51759
57 3ZDS M8O 3.51759
58 3OZ2 OZ2 3.52645
59 1N5S ADL 3.57143
60 1TZD ADP 3.63636
61 1I82 BGC BGC 3.7037
62 1OJJ GLC GAL 3.76884
63 1OJK GLC BGC 3.76884
64 5H9P TD2 3.79747
65 5VGS 9A4 3.82166
66 4XCB HY0 3.83142
67 1XKQ NDP 3.92857
68 2WA4 069 4.01146
69 6GR0 F8W 4.02299
70 3SCH TB6 4.0404
71 5C3R HMU 4.08163
72 5C3R AKG 4.08163
73 6G9I CXX 4.16667
74 1Y0G 8PP 4.18848
75 3P7N FMN 4.26357
76 4IE6 UN9 4.27136
77 4UHL VFV 4.27136
78 3DXW ICC 4.27136
79 2Z77 HE7 4.31655
80 4AVV GHE 4.41176
81 6CAM BGC 4.51977
82 5FBN 5WF 4.52261
83 3W8X FTK 4.52261
84 5LUN OGA 4.54545
85 1P0Z FLC 4.58015
86 4F4P 0SB 4.7619
87 4WUJ FMN 4.7619
88 5DQ8 FLF 5
89 2AMT GPP 5.03145
90 1WUB OTP 5.05618
91 3GUZ PAF 5.11364
92 1NP0 NGT 5.17241
93 4Z28 BTN 5.22388
94 4GJ3 0XP 5.29801
95 1BGQ RDC 5.33333
96 1T5B FMN 5.47264
97 6GBV FMN 5.47945
98 2E56 MYR 5.55556
99 4WVW SLT 5.55556
100 4GCZ FMN 5.71429
101 6A63 LAT 5.7971
102 5SVV FMN 5.83942
103 2PCU ASP 5.90164
104 3EW2 BTN 5.92593
105 5Y72 DST 5.97015
106 2RFZ CTR 6.03015
107 2RFY CBI 6.03015
108 3MI3 LYS 6.14657
109 4R6W SAH 6.20155
110 2WPB ZZI 6.25
111 1QFT HSM 6.28571
112 1W3T 3GR 6.46258
113 3WUC GLC GAL 6.56934
114 5FKP 6UL 6.66667
115 5GP0 GPP 6.71141
116 5L6G XYP 6.78392
117 3STK PLM 6.81818
118 4R57 ACO 6.81818
119 2NNQ T4B 6.87023
120 3AGC RCC 6.88406
121 2Y88 2ER 6.96721
122 2Z6C FMN 6.97674
123 1NOW IFG 7.03518
124 4X6F 3XU 7.11744
125 2YJ0 420 7.24638
126 4K55 H6P 7.25806
127 4MP8 NAD 7.37463
128 4MP8 MLI 7.37463
129 6FE1 V14 7.393
130 1U0A BGC BGC BGC BGC 7.47664
131 5IKH 6BW 7.53769
132 5EO8 TFU 7.71704
133 2CHT TSA 7.87402
134 4CQM NAP 8.04598
135 2J5B TYE 8.04598
136 4MNS 2AX 8.1761
137 5DYO FLU 8.25688
138 5NBW 8SK 8.41121
139 4FHD 0TT 8.42391
140 4FHD EEM 8.42391
141 4NG2 OHN 8.69565
142 4C2V YJA 8.79397
143 4HIA FMN 9.65909
144 3QP8 HL0 9.78261
145 5TBM 79A 10.2564
146 2YG2 FLC 10.4651
147 2YG2 S1P 10.4651
148 5B09 4MX 10.5769
149 4PSB GA3 11.6129
150 3WG3 A2G GAL NAG FUC 12.3596
151 1DQE BOM 13.1387
152 5KEW 6SB 14.8936
153 5UC4 83S 15.9091
154 4Y24 TD2 16.2338
155 5EZU MYR 16.8539
156 1SLT NDG GAL 17.9104
157 5E2N V14 18.6312
158 2P7Q GG6 21.8045
Pocket No.: 4; Query (leader) PDB : 1YKD; Ligand: CMP; Similar sites found with APoc: 104
This union binding pocket(no: 4) in the query (biounit: 1ykd.bio1) has 17 residues
No: Leader PDB Ligand Sequence Similarity
1 4YZC STU 1.25628
2 1Z03 OCH 1.25628
3 3AI7 TPP 1.25628
4 4QIJ 1HA 1.49701
5 3ETG NDP 1.50754
6 3ETG GLU 1.50754
7 4QDC ASD 1.53846
8 5AE2 FYC 1.75879
9 4IPM TCB 1.75879
10 2YNE YNE 1.82292
11 2YNE NHW 1.82292
12 5LY2 OGA 1.83727
13 2FVK DUC 1.9678
14 1MS9 LAT 2.01005
15 3L9R L9Q 2.04082
16 4V24 GYR 2.15633
17 4D52 GXL 2.22222
18 1PN0 IPH 2.26131
19 2DKH 3HB 2.26131
20 3B2Q ATP 2.26131
21 5Z46 8XL 2.26537
22 3TWO NDP 2.29885
23 1DY4 SNP 2.51256
24 5YBN AKG 2.54777
25 2AXR ABL 2.58449
26 3W68 VIV 2.63158
27 4HK8 XYP XYP XYP XYP XYP XYP 2.6455
28 1E3W NAD 2.68199
29 1E6W NAD 2.69231
30 5OX6 A1Z 2.77778
31 6GWR FEW 2.85714
32 3ECN IBM 2.95858
33 4PFC 2QX 3.01508
34 5XS3 VAL ARG SER ARG ARG CYS LEU ARG LEU 3.06122
35 1U7T NAD 3.06513
36 4NPL AKG 3.2
37 4MLO PAM 3.26087
38 4YLZ LAT NAG GAL 3.26797
39 2F57 23D 3.47003
40 4ZSI 4R1 3.50877
41 2VFT SOR 3.51759
42 5GUD 2IT 3.76884
43 5DRB 5FJ 3.78007
44 4XCB AKG 3.83142
45 5NIU 8YZ 3.90625
46 5HES 032 3.90879
47 3FW4 CAQ 3.93258
48 4USF 6UI 3.94737
49 4U0W 16G 4.06504
50 1MHC FME TYR PHE ILE ASN ILE LEU THR LEU 4.25532
51 2XN5 FUN 4.28571
52 3WW2 LPK 4.29688
53 3EEB IHP 4.30622
54 6AYU MLI 4.32277
55 2Y3S TIR 4.52261
56 3VKC FPQ 4.54545
57 5LUN ARG 4.54545
58 6GIN IR2 4.65116
59 1XHL NDP 4.7138
60 1J3R 6PG 4.73684
61 3SCM LGN 4.77387
62 4ARE FLC 4.77387
63 4BR5 ANP 4.814
64 1N62 MCN 4.81928
65 2TPS TPS 4.84582
66 4LED XXR 4.85075
67 1IY8 NAD 4.86891
68 1QKQ MAN 4.92958
69 1WNB BTL 5.25253
70 2DTX BMA 5.30303
71 2YIC TPP 5.52764
72 4RFM 3P6 5.6391
73 1LSH PLD 5.64263
74 3QRC SCR 5.73248
75 5MBC FMN 5.94901
76 4GKV NAD 5.95238
77 1IND EOT 6.04651
78 2ZAT NAP 6.15385
79 4B1M FRU FRU 6.28141
80 5LXT GTP 6.29371
81 5TPV TYD 6.53595
82 1NWW HPN 6.71141
83 5FPX GLY SER SER HIS HIS HIS HIS HIS 7.07965
84 2JIG PD2 7.58929
85 5BU3 4W9 7.6087
86 4DXD 9PC 7.82828
87 5ML3 DL3 8.05369
88 1NYW DAU 8.62944
89 6D6L FY4 9.41177
90 5NW7 9C2 9.799
91 1FFU CDP 9.81595
92 2HKA C3S 10
93 2GTE VA 10.4839
94 5KWY C3S 10.5263
95 2WLG SOP 10.804
96 4OIT BMA 11.5044
97 6CE2 SVR 13.2231
98 5FU3 BGC BGC BGC 14.1509
99 1Y2F WAI 14.3885
100 2QL9 CIT 14.4509
101 1MDC PLM 15.9091
102 1D5Z ACE ALC ARG ALA ODA SER LEU NH2 17.6796
103 6A56 LAT 21.3415
104 2HO2 PRO PRO PRO PRO PRO PRO PRO PRO PRO LEU 23.6842
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