Receptor
PDB id Resolution Class Description Source Keywords
1YXU 2.24 Å EC: 2.7.11.1 CRYSTAL STRUCTURE OF KINASE PIM1 IN COMPLEX WITH AMP HOMO SAPIENS SER/THR PROTEIN KINASE TRANSFERASE
Ref.: CRYSTAL STRUCTURES OF PROTO-ONCOGENE KINASE PIM1: A OF ABERRANT SOMATIC HYPERMUTATIONS IN DIFFUSE LARGE LYMPHOMA. J.MOL.BIOL. V. 348 183 2005
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
AMP A:550;
B:650;
C:750;
D:850;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
submit data
347.221 C10 H14 N5 O7 P c1nc(...
IMD A:500;
B:600;
C:700;
D:800;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
submit data
69.085 C3 H5 N2 c1c[n...
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4N70 2.1 Å EC: 2.7.11.1 PIM1 COMPLEXED WITH A PYRIDYLCARBOXAMIDE HOMO SAPIENS KINASE PHOSPHORYLATION TRANSFERASE-TRANSFERASE INHIBITOR C
Ref.: STRUCTURE GUIDED OPTIMIZATION, IN VITRO ACTIVITY, A VIVO ACTIVITY OF PAN-PIM KINASE INHIBITORS. ACS MED CHEM LETT V. 4 1193 2013
Members (68)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 107 families.
1 1XR1 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
2 4MBI - 26K C13 H17 N7 CN(C)CCNc1....
3 4MTA - 2D2 C12 H10 O3 Cc1c(cc(o1....
4 3VBT ic50 = 37 uM 0F9 C9 H7 Cl N2 O c1cc(c(cc1....
5 1YXX - LI7 C14 H10 N2 O2 c1ccc2c(c1....
6 5IIS Ki < 0.001 uM 6CB C23 H19 F N6 O Cc1cc(cc(n....
7 4K1B Ki = 0.003 nM 1OC C26 H24 F2 N8 O c1ccc(c(c1....
8 4XH6 ic50 = 2.71 uM HUL C16 H12 O6 COc1c(cc2c....
9 1YXU - AMP C10 H14 N5 O7 P c1nc(c2c(n....
10 1XWS - BI1 C25 H24 N4 O2 CN(C)CCCn1....
11 3R04 ic50 = 0.12 uM UNQ C19 H20 N4 O3 c1cc2c(cc1....
12 5IPJ ic50 = 0.3 nM 6CD C20 H23 N5 O2 C[C@@H]1c2....
13 2C3I Kd = 25 nM IYZ C18 H18 N4 O CC(=O)c1cc....
14 3VBW ic50 = 6 uM 0FN C10 H5 N O2 c1ccc2c(c1....
15 3F2A ic50 = 57 nM 985 C19 H22 N4 O2 C[N@]1CCCN....
16 4WT6 ic50 = 0.012 uM 3U6 C20 H20 N6 S c1cc(nc(c1....
17 4N70 Ki = 0.001 nM 2HX C23 H22 F3 N5 O2 C[C@H]1CN(....
18 4WRS ic50 = 0.4 nM 3U1 C24 H21 F2 N5 O c1cc(c(c(c....
19 2XIX - XIX C2 H5 N5 c1([nH]nc(....
20 2J2I ic50 = 0.2 uM LY4 C28 H28 N4 O3 CN(C)C[C@@....
21 3VBQ ic50 = 470 pM 0F5 C20 H23 N5 O2 S c1cc(cc(c1....
22 2OBJ ic50 = 0.05 uM VRV C18 H11 Br N2 O2 c1ccc(cc1)....
23 2O3P ic50 = 1.1 uM QUE C15 H10 O7 c1cc(c(cc1....
24 3VBY ic50 = 28 uM 0FR C13 H9 N O2 c1ccc2c(c1....
25 2XIY - XIY C8 H8 N2 O c1ccc2c(c1....
26 4A7C ic50 = 0.006 uM E46 C18 H19 F3 N6 O c1cc(cc(c1....
27 3BGQ Ki = 11 nM VX2 C18 H18 F3 N5 c1cc(cc(c1....
28 3R02 ic50 = 0.001 uM UNM C15 H17 Br N2 O3 c1c2cc(oc2....
29 4K18 Ki = 1.1 nM 1OB C21 H14 F N5 O2 c1cc(ccc1C....
30 5DIA - 5E6 C22 H23 N7 c1cc(nc(c1....
31 5KZI ic50 = 0.07 nM 6YN C22 H21 F2 N7 c1cc(c(c(c....
32 2BIK - BI1 C25 H24 N4 O2 CN(C)CCCn1....
33 4BZN ic50 = 1.441 uM UGX C18 H23 N3 O2 S CC(C)(C)CN....
34 3VBV ic50 = 10 uM 0FK C10 H8 N2 O2 c1cc2ccc(n....
35 3UIX ic50 = 0.151 uM Q17 C17 H18 N4 O c1ccc2c(c1....
36 1YXV - LI6 C10 H9 N O3 CN1c2ccccc....
37 3UMW ic50 = 3 nM 596 C22 H22 N4 O3 COc1ccc2c(....
38 1YHS ic50 = 0.01 uM STU C28 H26 N4 O3 C[C@@]12[C....
39 2XJ1 Kd = 28 nM XJ1 C19 H22 N4 O2 c1cc(cc(c1....
40 2O64 Kd = 0.34 uM MYU C15 H10 O8 c1cc(c(cc1....
41 4ALW ic50 = 27 nM HY7 C16 H17 Br N4 O2 CN1CCN(CC1....
42 3BGZ Ki = 0.55 uM VX3 C21 H15 N O2 c1ccc(cc1)....
43 2O63 Kd = 0.78 uM MYC C15 H10 O8 c1c(cc(c(c....
44 5V82 Ki = 0.07 nM 96Y C21 H19 F2 N7 Cc1cncc(n1....
45 3VC4 ic50 = 24 nM 0FS C11 H6 F3 N O2 S c1cc(cc(c1....
46 5DHJ Ki = 0.2 uM 5E5 C12 H10 N4 Cc1c2cc(nc....
47 2XIZ - XIZ C8 H7 N O2 c1cnccc1C=....
48 1YI3 ic50 = 4 uM LY2 C19 H17 N O3 c1ccc(cc1)....
49 2XJ2 Kd = 66 nM 985 C19 H22 N4 O2 C[N@]1CCCN....
50 1YI4 - ADN C10 H13 N5 O4 c1nc(c2c(n....
51 3R00 ic50 = 8.5 uM UNJ C9 H5 Br O3 c1cc2c(cc1....
52 3A99 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
53 3C4E ic50 ~ 100 uM C4E C13 H11 N3 c1ccc(cc1)....
54 3MA3 ic50 = 60 nM 01I C16 H8 O6 c1cc2c(cc(....
55 3VBX ic50 = 17 uM 0FO C9 H5 Br O3 c1cc2c(cc1....
56 5DGZ Ki = 14 nM L20 C24 H23 N5 O Cc1c2cc(cc....
57 2OI4 ic50 = 2.5 nM JM1 C23 H12 F N3 O3 Ru c1ccc2c(c1....
58 5EOL ic50 = 0.3 nM 5QO C21 H21 N5 O Cc1c2nc3c(....
59 3WE8 - RUI C18 H7 N2 O2 Ru c1cc2c3c4c....
60 3BWF ic50 = 0.6 nM DWC C23 H9 N3 O4 Os c1cc2c3c(c....
61 4WSY ic50 = 0.017 uM 3U5 C19 H13 N5 S c1ccc2c(c1....
62 4BZO ic50 = 0.013 uM 676 C22 H22 F N5 O2 c1ccc(cc1)....
63 5DWR Ki < 0.001 uM 5H7 C24 H23 F3 N4 O C[C@H]1C[C....
64 4XHK ic50 = 5 nM 3YR C19 H16 F2 N4 O2 S c1cc(c(c(c....
65 4K0Y Ki = 15 nM 1OA C18 H18 F N5 O2 c1cc(ccc1N....
66 4DTK ic50 < 0.004 uM 7LI C18 H23 N3 O3 S CC(C)Oc1cc....
67 4N6Z Ki = 16 nM 2HW C15 H19 N7 O c1cncc(c1N....
68 4AS0 - RPS C20 H19 N2 O3 Ru S3 c1c2c(cc3c....
70% Homology Family (68)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 82 families.
1 1XR1 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
2 4MBI - 26K C13 H17 N7 CN(C)CCNc1....
3 4MTA - 2D2 C12 H10 O3 Cc1c(cc(o1....
4 3VBT ic50 = 37 uM 0F9 C9 H7 Cl N2 O c1cc(c(cc1....
5 1YXX - LI7 C14 H10 N2 O2 c1ccc2c(c1....
6 5IIS Ki < 0.001 uM 6CB C23 H19 F N6 O Cc1cc(cc(n....
7 4K1B Ki = 0.003 nM 1OC C26 H24 F2 N8 O c1ccc(c(c1....
8 4XH6 ic50 = 2.71 uM HUL C16 H12 O6 COc1c(cc2c....
9 1YXU - AMP C10 H14 N5 O7 P c1nc(c2c(n....
10 1XWS - BI1 C25 H24 N4 O2 CN(C)CCCn1....
11 3R04 ic50 = 0.12 uM UNQ C19 H20 N4 O3 c1cc2c(cc1....
12 5IPJ ic50 = 0.3 nM 6CD C20 H23 N5 O2 C[C@@H]1c2....
13 2C3I Kd = 25 nM IYZ C18 H18 N4 O CC(=O)c1cc....
14 3VBW ic50 = 6 uM 0FN C10 H5 N O2 c1ccc2c(c1....
15 3F2A ic50 = 57 nM 985 C19 H22 N4 O2 C[N@]1CCCN....
16 4WT6 ic50 = 0.012 uM 3U6 C20 H20 N6 S c1cc(nc(c1....
17 4N70 Ki = 0.001 nM 2HX C23 H22 F3 N5 O2 C[C@H]1CN(....
18 4WRS ic50 = 0.4 nM 3U1 C24 H21 F2 N5 O c1cc(c(c(c....
19 2XIX - XIX C2 H5 N5 c1([nH]nc(....
20 2J2I ic50 = 0.2 uM LY4 C28 H28 N4 O3 CN(C)C[C@@....
21 3VBQ ic50 = 470 pM 0F5 C20 H23 N5 O2 S c1cc(cc(c1....
22 2OBJ ic50 = 0.05 uM VRV C18 H11 Br N2 O2 c1ccc(cc1)....
23 2O3P ic50 = 1.1 uM QUE C15 H10 O7 c1cc(c(cc1....
24 3VBY ic50 = 28 uM 0FR C13 H9 N O2 c1ccc2c(c1....
25 2XIY - XIY C8 H8 N2 O c1ccc2c(c1....
26 4A7C ic50 = 0.006 uM E46 C18 H19 F3 N6 O c1cc(cc(c1....
27 3BGQ Ki = 11 nM VX2 C18 H18 F3 N5 c1cc(cc(c1....
28 3R02 ic50 = 0.001 uM UNM C15 H17 Br N2 O3 c1c2cc(oc2....
29 4K18 Ki = 1.1 nM 1OB C21 H14 F N5 O2 c1cc(ccc1C....
30 5DIA - 5E6 C22 H23 N7 c1cc(nc(c1....
31 5KZI ic50 = 0.07 nM 6YN C22 H21 F2 N7 c1cc(c(c(c....
32 2BIK - BI1 C25 H24 N4 O2 CN(C)CCCn1....
33 4BZN ic50 = 1.441 uM UGX C18 H23 N3 O2 S CC(C)(C)CN....
34 3VBV ic50 = 10 uM 0FK C10 H8 N2 O2 c1cc2ccc(n....
35 3UIX ic50 = 0.151 uM Q17 C17 H18 N4 O c1ccc2c(c1....
36 1YXV - LI6 C10 H9 N O3 CN1c2ccccc....
37 3UMW ic50 = 3 nM 596 C22 H22 N4 O3 COc1ccc2c(....
38 1YHS ic50 = 0.01 uM STU C28 H26 N4 O3 C[C@@]12[C....
39 2XJ1 Kd = 28 nM XJ1 C19 H22 N4 O2 c1cc(cc(c1....
40 2O64 Kd = 0.34 uM MYU C15 H10 O8 c1cc(c(cc1....
41 4ALW ic50 = 27 nM HY7 C16 H17 Br N4 O2 CN1CCN(CC1....
42 3BGZ Ki = 0.55 uM VX3 C21 H15 N O2 c1ccc(cc1)....
43 2O63 Kd = 0.78 uM MYC C15 H10 O8 c1c(cc(c(c....
44 5V82 Ki = 0.07 nM 96Y C21 H19 F2 N7 Cc1cncc(n1....
45 3VC4 ic50 = 24 nM 0FS C11 H6 F3 N O2 S c1cc(cc(c1....
46 5DHJ Ki = 0.2 uM 5E5 C12 H10 N4 Cc1c2cc(nc....
47 2XIZ - XIZ C8 H7 N O2 c1cnccc1C=....
48 1YI3 ic50 = 4 uM LY2 C19 H17 N O3 c1ccc(cc1)....
49 2XJ2 Kd = 66 nM 985 C19 H22 N4 O2 C[N@]1CCCN....
50 1YI4 - ADN C10 H13 N5 O4 c1nc(c2c(n....
51 3R00 ic50 = 8.5 uM UNJ C9 H5 Br O3 c1cc2c(cc1....
52 3A99 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
53 3C4E ic50 ~ 100 uM C4E C13 H11 N3 c1ccc(cc1)....
54 3MA3 ic50 = 60 nM 01I C16 H8 O6 c1cc2c(cc(....
55 3VBX ic50 = 17 uM 0FO C9 H5 Br O3 c1cc2c(cc1....
56 5DGZ Ki = 14 nM L20 C24 H23 N5 O Cc1c2cc(cc....
57 2OI4 ic50 = 2.5 nM JM1 C23 H12 F N3 O3 Ru c1ccc2c(c1....
58 5EOL ic50 = 0.3 nM 5QO C21 H21 N5 O Cc1c2nc3c(....
59 3WE8 - RUI C18 H7 N2 O2 Ru c1cc2c3c4c....
60 3BWF ic50 = 0.6 nM DWC C23 H9 N3 O4 Os c1cc2c3c(c....
61 4WSY ic50 = 0.017 uM 3U5 C19 H13 N5 S c1ccc2c(c1....
62 4BZO ic50 = 0.013 uM 676 C22 H22 F N5 O2 c1ccc(cc1)....
63 5DWR Ki < 0.001 uM 5H7 C24 H23 F3 N4 O C[C@H]1C[C....
64 4XHK ic50 = 5 nM 3YR C19 H16 F2 N4 O2 S c1cc(c(c(c....
65 4K0Y Ki = 15 nM 1OA C18 H18 F N5 O2 c1cc(ccc1N....
66 4DTK ic50 < 0.004 uM 7LI C18 H23 N3 O3 S CC(C)Oc1cc....
67 4N6Z Ki = 16 nM 2HW C15 H19 N7 O c1cncc(c1N....
68 4AS0 - RPS C20 H19 N2 O3 Ru S3 c1c2c(cc3c....
50% Homology Family (69)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 55 families.
1 1XR1 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
2 4MBI - 26K C13 H17 N7 CN(C)CCNc1....
3 4MTA - 2D2 C12 H10 O3 Cc1c(cc(o1....
4 3VBT ic50 = 37 uM 0F9 C9 H7 Cl N2 O c1cc(c(cc1....
5 1YXX - LI7 C14 H10 N2 O2 c1ccc2c(c1....
6 5IIS Ki < 0.001 uM 6CB C23 H19 F N6 O Cc1cc(cc(n....
7 4K1B Ki = 0.003 nM 1OC C26 H24 F2 N8 O c1ccc(c(c1....
8 4XH6 ic50 = 2.71 uM HUL C16 H12 O6 COc1c(cc2c....
9 1YXU - AMP C10 H14 N5 O7 P c1nc(c2c(n....
10 1XWS - BI1 C25 H24 N4 O2 CN(C)CCCn1....
11 3R04 ic50 = 0.12 uM UNQ C19 H20 N4 O3 c1cc2c(cc1....
12 5IPJ ic50 = 0.3 nM 6CD C20 H23 N5 O2 C[C@@H]1c2....
13 2C3I Kd = 25 nM IYZ C18 H18 N4 O CC(=O)c1cc....
14 3VBW ic50 = 6 uM 0FN C10 H5 N O2 c1ccc2c(c1....
15 3F2A ic50 = 57 nM 985 C19 H22 N4 O2 C[N@]1CCCN....
16 4WT6 ic50 = 0.012 uM 3U6 C20 H20 N6 S c1cc(nc(c1....
17 4N70 Ki = 0.001 nM 2HX C23 H22 F3 N5 O2 C[C@H]1CN(....
18 4WRS ic50 = 0.4 nM 3U1 C24 H21 F2 N5 O c1cc(c(c(c....
19 2XIX - XIX C2 H5 N5 c1([nH]nc(....
20 2J2I ic50 = 0.2 uM LY4 C28 H28 N4 O3 CN(C)C[C@@....
21 3VBQ ic50 = 470 pM 0F5 C20 H23 N5 O2 S c1cc(cc(c1....
22 2OBJ ic50 = 0.05 uM VRV C18 H11 Br N2 O2 c1ccc(cc1)....
23 2O3P ic50 = 1.1 uM QUE C15 H10 O7 c1cc(c(cc1....
24 3VBY ic50 = 28 uM 0FR C13 H9 N O2 c1ccc2c(c1....
25 2XIY - XIY C8 H8 N2 O c1ccc2c(c1....
26 4A7C ic50 = 0.006 uM E46 C18 H19 F3 N6 O c1cc(cc(c1....
27 3BGQ Ki = 11 nM VX2 C18 H18 F3 N5 c1cc(cc(c1....
28 3R02 ic50 = 0.001 uM UNM C15 H17 Br N2 O3 c1c2cc(oc2....
29 4K18 Ki = 1.1 nM 1OB C21 H14 F N5 O2 c1cc(ccc1C....
30 5DIA - 5E6 C22 H23 N7 c1cc(nc(c1....
31 5KZI ic50 = 0.07 nM 6YN C22 H21 F2 N7 c1cc(c(c(c....
32 2BIK - BI1 C25 H24 N4 O2 CN(C)CCCn1....
33 4BZN ic50 = 1.441 uM UGX C18 H23 N3 O2 S CC(C)(C)CN....
34 3VBV ic50 = 10 uM 0FK C10 H8 N2 O2 c1cc2ccc(n....
35 3UIX ic50 = 0.151 uM Q17 C17 H18 N4 O c1ccc2c(c1....
36 1YXV - LI6 C10 H9 N O3 CN1c2ccccc....
37 3UMW ic50 = 3 nM 596 C22 H22 N4 O3 COc1ccc2c(....
38 1YHS ic50 = 0.01 uM STU C28 H26 N4 O3 C[C@@]12[C....
39 2XJ1 Kd = 28 nM XJ1 C19 H22 N4 O2 c1cc(cc(c1....
40 2O64 Kd = 0.34 uM MYU C15 H10 O8 c1cc(c(cc1....
41 4ALW ic50 = 27 nM HY7 C16 H17 Br N4 O2 CN1CCN(CC1....
42 3BGZ Ki = 0.55 uM VX3 C21 H15 N O2 c1ccc(cc1)....
43 2O63 Kd = 0.78 uM MYC C15 H10 O8 c1c(cc(c(c....
44 5V82 Ki = 0.07 nM 96Y C21 H19 F2 N7 Cc1cncc(n1....
45 3VC4 ic50 = 24 nM 0FS C11 H6 F3 N O2 S c1cc(cc(c1....
46 5DHJ Ki = 0.2 uM 5E5 C12 H10 N4 Cc1c2cc(nc....
47 2XIZ - XIZ C8 H7 N O2 c1cnccc1C=....
48 1YI3 ic50 = 4 uM LY2 C19 H17 N O3 c1ccc(cc1)....
49 2XJ2 Kd = 66 nM 985 C19 H22 N4 O2 C[N@]1CCCN....
50 1YI4 - ADN C10 H13 N5 O4 c1nc(c2c(n....
51 3R00 ic50 = 8.5 uM UNJ C9 H5 Br O3 c1cc2c(cc1....
52 3A99 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
53 3C4E ic50 ~ 100 uM C4E C13 H11 N3 c1ccc(cc1)....
54 3MA3 ic50 = 60 nM 01I C16 H8 O6 c1cc2c(cc(....
55 3VBX ic50 = 17 uM 0FO C9 H5 Br O3 c1cc2c(cc1....
56 5DGZ Ki = 14 nM L20 C24 H23 N5 O Cc1c2cc(cc....
57 2OI4 ic50 = 2.5 nM JM1 C23 H12 F N3 O3 Ru c1ccc2c(c1....
58 5EOL ic50 = 0.3 nM 5QO C21 H21 N5 O Cc1c2nc3c(....
59 3WE8 - RUI C18 H7 N2 O2 Ru c1cc2c3c4c....
60 3BWF ic50 = 0.6 nM DWC C23 H9 N3 O4 Os c1cc2c3c(c....
61 4WSY ic50 = 0.017 uM 3U5 C19 H13 N5 S c1ccc2c(c1....
62 4BZO ic50 = 0.013 uM 676 C22 H22 F N5 O2 c1ccc(cc1)....
63 5DWR Ki < 0.001 uM 5H7 C24 H23 F3 N4 O C[C@H]1C[C....
64 4XHK ic50 = 5 nM 3YR C19 H16 F2 N4 O2 S c1cc(c(c(c....
65 4K0Y Ki = 15 nM 1OA C18 H18 F N5 O2 c1cc(ccc1N....
66 4DTK ic50 < 0.004 uM 7LI C18 H23 N3 O3 S CC(C)Oc1cc....
67 4N6Z Ki = 16 nM 2HW C15 H19 N7 O c1cncc(c1N....
68 4AS0 - RPS C20 H19 N2 O3 Ru S3 c1c2c(cc3c....
69 4X7Q ic50 = 14 nM 3YR C19 H16 F2 N4 O2 S c1cc(c(c(c....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: AMP; Similar ligands found: 382
No: Ligand ECFP6 Tc MDL keys Tc
1 AMP 1 1
2 A 1 1
3 A2D 0.833333 0.943662
4 ABM 0.833333 0.943662
5 ADP 0.823529 0.971429
6 AMP MG 0.818182 0.916667
7 A12 0.808824 0.931507
8 AP2 0.808824 0.931507
9 BA3 0.808824 0.943662
10 SRA 0.80303 0.944444
11 AP5 0.797101 0.943662
12 B4P 0.797101 0.943662
13 ATP 0.788732 0.971429
14 AN2 0.785714 0.957747
15 APC 0.777778 0.931507
16 AQP 0.777778 0.971429
17 5FA 0.777778 0.971429
18 ADX 0.774648 0.848101
19 CA0 0.774648 0.917808
20 M33 0.774648 0.930556
21 AU1 0.774648 0.944444
22 ACP 0.763889 0.944444
23 50T 0.763889 0.957747
24 25A 0.75641 0.971429
25 AR6 0.753425 0.943662
26 APR 0.753425 0.943662
27 PRX 0.753425 0.917808
28 ADP MG 0.75 0.90411
29 TAT 0.746667 0.931507
30 ACQ 0.746667 0.944444
31 RBY 0.743243 0.905405
32 SAP 0.743243 0.918919
33 AGS 0.743243 0.918919
34 ADV 0.743243 0.905405
35 AD9 0.743243 0.944444
36 BEF ADP 0.739726 0.88
37 ADP BEF 0.739726 0.88
38 ANP 0.723684 0.944444
39 ADP PO3 0.72 0.942857
40 5AL 0.714286 0.930556
41 SON 0.712329 0.931507
42 ATP MG 0.710526 0.90411
43 ADN 0.709677 0.842857
44 XYA 0.709677 0.842857
45 RAB 0.709677 0.842857
46 ATF 0.705128 0.931507
47 GAP 0.701299 0.891892
48 A22 0.7 0.957747
49 SRP 0.696203 0.905405
50 7D5 0.691176 0.902778
51 A3P 0.684932 0.971014
52 A2P 0.684932 0.956522
53 ALF ADP 0.683544 0.868421
54 ADP ALF 0.683544 0.868421
55 ADQ 0.682927 0.917808
56 MAP 0.679012 0.918919
57 ANP MG 0.675 0.893333
58 ADP VO4 0.675 0.930556
59 VO4 ADP 0.675 0.930556
60 5SV 0.670732 0.87013
61 OOB 0.670732 0.930556
62 8QN 0.670732 0.930556
63 PTJ 0.670588 0.894737
64 AOC 0.666667 0.84507
65 4AD 0.662651 0.893333
66 A1R 0.662651 0.881579
67 AMO 0.662651 0.905405
68 PAJ 0.662651 0.858974
69 5N5 0.661538 0.816901
70 DAL AMP 0.658537 0.90411
71 IMO 0.657534 0.928571
72 DLL 0.654762 0.930556
73 AHX 0.654762 0.87013
74 00A 0.654762 0.881579
75 5AS 0.653333 0.776471
76 5CD 0.651515 0.828571
77 A4D 0.651515 0.816901
78 3UK 0.647059 0.917808
79 ADP BMA 0.647059 0.891892
80 OAD 0.647059 0.917808
81 25L 0.643678 0.957747
82 PR8 0.639535 0.848101
83 WAQ 0.639535 0.881579
84 LAD 0.639535 0.858974
85 DTA 0.637681 0.808219
86 V3L 0.6375 0.971429
87 3DH 0.633803 0.794521
88 BIS 0.632184 0.906667
89 TXA 0.632184 0.905405
90 FYA 0.632184 0.930556
91 ME8 0.632184 0.8375
92 1ZZ 0.632184 0.8375
93 3OD 0.632184 0.917808
94 NB8 0.632184 0.87013
95 MTA 0.628571 0.794521
96 3AM 0.625 0.956522
97 EP4 0.623188 0.773333
98 A A 0.62069 0.971429
99 9SN 0.617977 0.87013
100 M2T 0.614286 0.753247
101 JB6 0.613636 0.881579
102 YAP 0.611111 0.893333
103 FA5 0.611111 0.905405
104 MYR AMP 0.606742 0.814815
105 G5A 0.604938 0.776471
106 XAH 0.604396 0.8375
107 4UV 0.597826 0.893333
108 71V 0.597403 0.906667
109 ATP A A A 0.593407 0.929577
110 PAP 0.592593 0.957143
111 G3A 0.591398 0.894737
112 2AM 0.589041 0.942857
113 5X8 0.5875 0.783784
114 TYR AMP 0.586957 0.88
115 6RE 0.586667 0.779221
116 6C6 0.585366 0.905405
117 4UU 0.585106 0.893333
118 G5P 0.585106 0.894737
119 AFH 0.585106 0.858974
120 7D3 0.584416 0.878378
121 A5A 0.583333 0.804878
122 TSB 0.581395 0.795181
123 AMP DBH 0.580645 0.891892
124 2A5 0.580247 0.891892
125 DSH 0.578947 0.74359
126 TAD 0.578947 0.858974
127 GTA 0.578947 0.860759
128 6IA 0.578313 0.858974
129 SSA 0.576471 0.776471
130 C2R 0.575342 0.876712
131 AMZ 0.575342 0.888889
132 7D4 0.575 0.878378
133 PGS 0.575 0.857143
134 ZAS 0.573333 0.786667
135 ATR 0.573171 0.942857
136 LAQ 0.572917 0.8375
137 PPS 0.571429 0.848101
138 AAM 0.571429 1
139 AIR 0.571429 0.927536
140 J7C 0.571429 0.789474
141 A3N 0.571429 0.783784
142 54H 0.569767 0.785714
143 VMS 0.569767 0.785714
144 52H 0.569767 0.776471
145 7MD 0.568421 0.8375
146 AR6 AR6 0.568421 0.916667
147 48N 0.56701 0.87013
148 YLP 0.56701 0.817073
149 OVE 0.565789 0.90411
150 UPA 0.565657 0.881579
151 2SA 0.564706 0.905405
152 S4M 0.564103 0.682353
153 53H 0.563218 0.776471
154 5CA 0.563218 0.776471
155 4UW 0.561224 0.858974
156 NAI 0.561224 0.881579
157 TXD 0.561224 0.881579
158 6V0 0.561224 0.87013
159 UP5 0.561224 0.893333
160 DND 0.561224 0.905405
161 NXX 0.561224 0.905405
162 NAX 0.561224 0.848101
163 NIA 0.56 0.820513
164 D5M 0.558442 0.902778
165 DA 0.558442 0.902778
166 MAO 0.556962 0.777778
167 AHZ 0.556701 0.814815
168 ARG AMP 0.556701 0.82716
169 ITT 0.555556 0.915493
170 TXE 0.555556 0.881579
171 TYM 0.555556 0.905405
172 OMR 0.555556 0.82716
173 5AD 0.552239 0.768116
174 A2R 0.551724 0.957747
175 LPA AMP 0.55102 0.814815
176 DSZ 0.550562 0.776471
177 LSS 0.550562 0.758621
178 NSS 0.550562 0.776471
179 YLB 0.55 0.817073
180 YLC 0.55 0.8375
181 4TC 0.55 0.87013
182 AP0 0.55 0.87013
183 P5A 0.549451 0.741573
184 139 0.54902 0.848101
185 A4P 0.544554 0.819277
186 NVA LMS 0.544444 0.758621
187 GJV 0.544304 0.769231
188 7D7 0.544118 0.763889
189 A7D 0.54321 0.797297
190 ALF ADP 3PG 0.54 0.835443
191 LA8 ALF 3PG 0.54 0.835443
192 AF3 ADP 3PG 0.54 0.835443
193 6K6 0.539326 0.957143
194 IOT 0.539216 0.829268
195 LEU LMS 0.538462 0.758621
196 A3G 0.538462 0.797297
197 A5D 0.535714 0.808219
198 7MC 0.534653 0.817073
199 T5A 0.533981 0.817073
200 YLA 0.533981 0.817073
201 ADJ 0.533981 0.82716
202 KAA 0.532609 0.75
203 GSU 0.532609 0.776471
204 7RA 0.531646 0.985507
205 SFG 0.53012 0.77027
206 SAH 0.529412 0.763158
207 AYB 0.528846 0.807229
208 CNA 0.528846 0.905405
209 N6P 0.527473 0.942029
210 8BR 0.525 0.931507
211 Y3J 0.521127 0.746479
212 YSA 0.520833 0.776471
213 7RP 0.518987 0.955882
214 G A A A 0.518868 0.87013
215 COD 0.518868 0.788235
216 BTX 0.518868 0.839506
217 NAD 0.518868 0.930556
218 MHZ 0.518072 0.714286
219 SA8 0.517647 0.725
220 6AD 0.517241 0.883117
221 DZD 0.514019 0.858974
222 BT5 0.514019 0.829268
223 RMB 0.5125 0.898551
224 SAI 0.511628 0.753247
225 AV2 0.511364 0.890411
226 NAD IBO 0.509434 0.868421
227 A3D 0.509259 0.917808
228 A3S 0.506024 0.808219
229 SAM 0.505747 0.707317
230 3AT 0.505747 0.943662
231 SMM 0.505618 0.702381
232 NA7 0.505376 0.931507
233 4TA 0.504673 0.804878
234 5GP 0.5 0.905405
235 EEM 0.5 0.707317
236 NEC 0.5 0.743243
237 AAT 0.5 0.725
238 G 0.5 0.905405
239 YLY 0.495495 0.807229
240 M24 0.495495 0.848101
241 7C5 0.494949 0.815789
242 DAT 0.494118 0.878378
243 A3T 0.494118 0.819444
244 FAI 0.493827 0.888889
245 P2P 0.493827 0.928571
246 1RB 0.493671 0.911765
247 NAE 0.491071 0.893333
248 NAJ PZO 0.490909 0.846154
249 TM1 0.489583 0.771084
250 A6D 0.489362 0.740741
251 PO4 PO4 A A A A PO4 0.489362 0.901408
252 A A A 0.489362 0.90411
253 S7M 0.488889 0.707317
254 DTP 0.488636 0.878378
255 101 0.4875 0.902778
256 RBZ 0.4875 0.873239
257 EAD 0.486957 0.848101
258 NAQ 0.486726 0.87013
259 U A G G 0.486239 0.881579
260 4YB 0.485149 0.758621
261 NDE 0.483051 0.931507
262 N0B 0.482456 0.817073
263 ZID 0.482456 0.917808
264 WSA 0.480769 0.785714
265 RGT 0.479592 0.931507
266 ARU 0.478723 0.835443
267 GGZ 0.478261 0.8
268 JLN 0.47561 0.863014
269 ANZ 0.475248 0.820513
270 ACK 0.475 0.885714
271 QQY 0.475 0.837838
272 NAJ PYZ 0.473684 0.848101
273 S8M 0.473118 0.779221
274 GEK 0.473118 0.734177
275 AVV 0.473118 0.87013
276 3AD 0.472973 0.828571
277 A U 0.471698 0.868421
278 P1H 0.470588 0.82716
279 AMP NAD 0.469565 0.88
280 0UM 0.468085 0.716049
281 RVP 0.467532 0.847222
282 649 0.466667 0.741573
283 Z5A 0.465517 0.776471
284 PMO 0.464286 0.873239
285 SXZ 0.463918 0.707317
286 62X 0.463158 0.682353
287 QQX 0.4625 0.826667
288 2VA 0.45977 0.797297
289 IMP 0.458824 0.90411
290 K15 0.458333 0.698795
291 CC5 0.458333 0.84058
292 AS 0.457831 0.855263
293 DDS 0.455556 0.851351
294 V1N 0.455446 0.943662
295 NJP 0.454545 0.918919
296 93A 0.453488 0.804878
297 G7M 0.453488 0.87013
298 7DD 0.453488 0.957143
299 3D1 0.453333 0.77027
300 3L1 0.453333 0.77027
301 NDC 0.45082 0.87013
302 FB0 0.45082 0.781609
303 0WD 0.45045 0.894737
304 26A 0.447368 0.76
305 2FA 0.447368 0.810811
306 CMP 0.447059 0.927536
307 2BA 0.447059 0.914286
308 D3Y 0.446809 0.786667
309 SO8 0.444444 0.786667
310 APU 0.444444 0.893333
311 VRT 0.444444 0.766234
312 KB1 0.444444 0.716049
313 FDA 0.443548 0.809524
314 PUA 0.443478 0.858974
315 ODP 0.441441 0.883117
316 6FA 0.44 0.817073
317 RP1 0.439024 0.864865
318 SP1 0.439024 0.864865
319 103 0.439024 0.861111
320 3NZ 0.438776 0.779221
321 7DT 0.438202 0.957143
322 U G A 0.436508 0.8375
323 NDP 0.436364 0.894737
324 NPW 0.436364 0.860759
325 MTP 0.434211 0.727273
326 NVA 2AD 0.433333 0.74026
327 FAD 0.433071 0.82716
328 SFD 0.433071 0.712766
329 FAS 0.433071 0.82716
330 TXP 0.432432 0.894737
331 IRN 0.432432 0.867647
332 NZQ 0.432432 0.883117
333 ZZB 0.432432 0.792683
334 FNK 0.430769 0.781609
335 62F 0.430769 0.8375
336 128 0.429907 0.752941
337 PLP AAD 0.429825 0.758621
338 PAX 0.428571 0.82716
339 6MD 0.428571 0.805556
340 1DA 0.428571 0.842857
341 SLU 0.426087 0.767442
342 XNP 0.424779 0.848101
343 12D 0.424528 0.761905
344 5F1 0.423077 0.72973
345 ETB 0.422414 0.809524
346 DCA 0.422414 0.8
347 WMP 0.421053 0.864865
348 GUO 0.421053 0.864865
349 FAY 0.416667 0.8375
350 38Y 0.415929 0.804878
351 5J9 0.415842 0.728395
352 NAD BBN 0.415385 0.817073
353 0T1 0.415254 0.8
354 COA 0.415254 0.8
355 KH3 0.415094 0.690476
356 FMP 0.413793 0.871429
357 U A C C 0.413793 0.857143
358 N01 0.413793 0.90411
359 RFL 0.413534 0.797619
360 NMN AMP PO4 0.412281 0.868421
361 NAD CJ3 0.409091 0.788235
362 GDP 0.408602 0.893333
363 GP2 0.408602 0.858974
364 NAP 0.408333 0.944444
365 NOC 0.407895 0.760563
366 CNV FAD 0.407407 0.770115
367 2ER 0.405941 0.831169
368 1PR 0.405941 0.820513
369 P5F 0.405797 0.8
370 TAP 0.404959 0.906667
371 CAO 0.404959 0.772727
372 AMX 0.404959 0.809524
373 COS 0.404959 0.781609
374 30N 0.404959 0.731183
375 XMP 0.402299 0.891892
376 G2P 0.402062 0.858974
377 APC G U 0.401709 0.833333
378 U A A U 0.401639 0.906667
379 CMX 0.401639 0.8
380 SCO 0.401639 0.8
381 NA0 0.401639 0.931507
382 F2N 0.4 0.790698
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4N70; Ligand: 2HX; Similar sites found: 312
This union binding pocket(no: 1) in the query (biounit: 4n70.bio1) has 46 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 5TPU TYD 0.02702 0.43064 None
2 1D8C GLV 0.04231 0.41328 1.52439
3 2DQA NAG NAG NAG 0.03851 0.41142 1.6129
4 2IF8 ADP 0.00028 0.53759 1.82927
5 3K5I ADP 0.004437 0.43755 1.82927
6 4RDL FUC GAL NDG FUC 0.004577 0.4745 1.94805
7 3LHS SF8 0.02879 0.42603 2.02703
8 2AQX ATP 0.00177 0.45249 2.07612
9 3X01 AMP 0.0007082 0.51841 2.13415
10 3ORQ ADP 0.001232 0.46348 2.13415
11 5JDA AMP 0.04847 0.40233 2.13415
12 4FE2 AIR 0.01161 0.43918 2.35294
13 4FE2 ADP 0.01503 0.42933 2.35294
14 1PK8 ATP 0.0008149 0.457 2.36967
15 4ZGP ADP 0.00215 0.46403 2.38908
16 4B1L FRU 0.03925 0.40487 2.42424
17 2YW2 ATP 0.003081 0.44493 2.43902
18 2ZWS PLM 0.04305 0.43659 2.43902
19 4C2C ALA ALA ALA 0.03642 0.42253 2.43902
20 3SJK LYS PRO VAL LEU ARG THR ALA 0.007859 0.45986 2.63158
21 3TM0 ANP 0.0001498 0.46747 2.6616
22 3TM0 B31 0.0001882 0.46047 2.6616
23 2PUL ACP 0.00001707 0.56772 2.7439
24 5DZT AMP 0.0004718 0.527 2.7439
25 1EHI ADP 0.001618 0.46182 2.7439
26 1I7L ATP 0.0007886 0.46111 2.7439
27 2IO8 ADP 0.001317 0.4513 2.7439
28 4ZWP M44 0.04627 0.41442 2.7439
29 3R4S SLB 0.04514 0.40685 2.7439
30 3QRC SCR 0.01386 0.4424 3.18471
31 4IAW LIZ 0.04952 0.40903 3.19149
32 1A8U BEZ 0.03844 0.41659 3.2491
33 1K4M CIT 0.04161 0.42094 3.28639
34 5I35 ANP 0.00000169 0.6173 3.35366
35 3VOT ADP 0.0009455 0.49668 3.35366
36 1HFU NAG NDG 0.01153 0.4691 3.35366
37 3TII ANP 0.003695 0.46546 3.35366
38 2Z9I GLY ALA THR VAL 0.02897 0.43153 3.39506
39 1ZP9 ATP 0.000003621 0.60822 3.48837
40 2VQD AP2 0.0007065 0.47471 3.65854
41 3KAL ADP 0.001504 0.42555 3.65854
42 4OCJ NDG 0.00006939 0.41902 3.65854
43 5JM8 ATP 0.009612 0.41885 3.65854
44 4EIL CB3 0.0459 0.40732 3.65854
45 4OCV ANP 0.00002807 0.54534 3.96341
46 3V4S ATP 0.002786 0.44348 3.96341
47 3HQP OXL 0.02253 0.41032 3.96341
48 4K37 SAM 0.02648 0.40993 3.96341
49 4K38 SAM 0.02572 0.40459 3.96341
50 4OAS 2SW 0.02692 0.41278 4.16667
51 2GQS ADP 0.007503 0.43717 4.21941
52 5C1P ADP 0.004606 0.45591 4.24837
53 3VPC ADP 0.0003792 0.48306 4.25532
54 4UYW H1S 0.0015 0.54939 4.26829
55 5NCY 8TK 0.0001089 0.47973 4.26829
56 3E7S AT2 0.03894 0.41913 4.26829
57 4XMF HSM 0.0004735 0.53025 4.34783
58 3ZJX BOG 0.004259 0.47509 4.49827
59 4XBT 3ZQ 0.01206 0.42355 4.51613
60 4XBT FLC 0.01307 0.42186 4.51613
61 4GYI ADP 0.00001017 0.59279 4.57317
62 2X3J ATP 0.01745 0.40974 4.57317
63 3A6T 8OG 0.01795 0.41836 4.65116
64 3HAV ATP 0.0002134 0.54628 4.68227
65 3DNT ATP 0.0003717 0.47551 4.77273
66 4PU5 ANP 0.0003856 0.47868 4.87805
67 4ZS4 ATP 0.00003222 0.5425 4.88599
68 1IA9 ANP 0.000157 0.50988 5
69 4CC6 L5Y 0.001891 0.48608 5.03145
70 2YRX AMP 0.02653 0.42754 5.09978
71 4R78 AMP 0.000002376 0.64256 5.17799
72 2PYW ADP 0.000004046 0.57904 5.18293
73 2Q7D ANP 0.00266 0.43177 5.18293
74 3CV2 OXL 0.02384 0.42904 5.18293
75 4YRD 3IT 0.0277 0.4265 5.18293
76 1FWV SGA MAG FUC 0.005583 0.45992 5.22388
77 3VPB ADP 0.0002234 0.48134 5.35714
78 1U18 HSM 0.008799 0.42134 5.40541
79 3PDT ADP 0.00007538 0.54176 5.45455
80 1LOP SIN ALA PRO ALA NIT 0.03116 0.42455 5.4878
81 5C4L 4XR 0.00002434 0.41746 5.60748
82 1TQP ATP 0.000001279 0.58404 5.67376
83 5CAD PCA 0.03918 0.41259 5.79268
84 5T7I LAT NAG GAL 0.04506 0.4164 5.80645
85 5MG2 7M8 0.04408 0.41182 5.83942
86 4O4F ATP 0.001004 0.45307 6.04839
87 4O4F IHP 0.001113 0.44788 6.04839
88 4U98 ACP 0.0006859 0.48853 6.09756
89 5MRH Q9Z 0.01361 0.4397 6.09756
90 5FJJ MAN 0.01062 0.4202 6.09756
91 4LH7 1X8 0.001242 0.49977 6.19195
92 5T96 79J 0.02424 0.43556 6.40244
93 4WW7 AMP 0.0000001187 0.43222 6.51341
94 5MY8 RXZ 0.000001318 0.57785 6.70732
95 3I0O ADP 0.0002316 0.52888 6.70732
96 4UWH JXM 0.000419 0.5042 6.70732
97 3W0O ADP 0.00003085 0.50193 6.70732
98 3W0O HY0 0.00003085 0.50193 6.70732
99 3I0O SMI 0.04054 0.42034 6.70732
100 1QY1 PRZ 0.01946 0.40476 6.89655
101 5NBW 8SK 0.04666 0.40363 7.20721
102 4D4U FUC NDG GAL FUC 0.04545 0.41093 7.30159
103 3CTL S6P 0.02053 0.40929 7.35931
104 5O4F 8VE 0.03619 0.41653 7.36434
105 2CFM AMP 0.0009744 0.49599 7.92683
106 5DXT 5H5 0.006362 0.43357 7.92683
107 3UYW TAU 0.01583 0.4371 7.94393
108 3WVR AMP 0.0007333 0.49194 8.23171
109 4DFU QUE 0.002717 0.48301 8.38509
110 4XYM A12 0.0008162 0.47592 8.53659
111 5GZK BGC 0.02327 0.406 8.53659
112 5HWC FK5 0.04308 0.41237 8.69565
113 1PVC ILE SER GLU VAL 0.04905 0.42284 8.82353
114 4K55 H6P 0.02062 0.42999 8.87097
115 1GUX ASP LEU TYR CYS TYR GLU GLN LEU ASN 0.03085 0.4066 9.21053
116 4OAV ACP 0.0000003263 0.65256 9.45122
117 5GZ9 ANP 0.0000005922 0.42897 9.83607
118 2BKK ADP 0.00002172 0.57581 10.0592
119 4RYV ZEA 0.03065 0.41674 10.3226
120 4ANW O92 0.00006516 0.48168 10.9756
121 1RGE 2GP 0.04941 0.41366 11.4583
122 1RNT 2GP 0.01939 0.41048 11.5385
123 3TDV GDP 0.000003823 0.59293 12.4183
124 3H9R TAK 0.0001112 0.55247 12.5
125 4NS0 PIO 0.01295 0.44691 12.782
126 2QLU ADE 0.0008328 0.50162 13.0573
127 1VJY 460 0.00000003239 0.61144 13.5314
128 1LNX URI 0.04315 0.41778 13.5802
129 4Z4P SAH 0.038 0.40206 14.4578
130 4Q5H ANP 0.0000002462 0.65055 14.4737
131 4AZT LY2 0.001295 0.48947 14.6341
132 3E8N ATP 0.000001411 0.50505 14.939
133 3E8N VRA 0.000001411 0.50505 14.939
134 5CKW ANP 0.000003398 0.62549 15.2439
135 5KBE IPH 0.03207 0.4234 15.2838
136 4O1P ANP 0.0000006253 0.40406 16.7683
137 3GNI ATP 0.000003571 0.58156 17.6829
138 3KMW ATP 0.0006549 0.48952 18.0812
139 1TZD ADP 0.0006359 0.51474 18.1818
140 5W2I ADP 0.000667 0.46432 18.677
141 5W2I I3P 0.000667 0.46432 18.677
142 4BKJ STI 0.0005568 0.46416 19.3651
143 4Y85 499 0.00001852 0.56597 19.8171
144 1W2D ADP 0.004253 0.46224 20
145 1W2D 4IP 0.002769 0.42542 20
146 5USZ SKE 0.0000002702 0.59609 20.0692
147 5C03 AGS 0.000001187 0.61751 20.122
148 4YZC STU 0.0000001628 0.49094 20.4268
149 3LQV ADE 0.01618 0.43282 20.5128
150 4WOV 3SM 0.00002914 0.56924 20.8202
151 5VC5 96M 0.000002946 0.42926 21.1073
152 4K33 ACP 0.00000008975 0.42934 21.8462
153 1Y57 MPZ 0.0000002505 0.62162 21.9512
154 2H8H H8H 0.000002442 0.60235 21.9512
155 4AT3 LTI 0.000149 0.47422 22.0736
156 2X2M X2M 0.0000003096 0.42847 22.6115
157 3RI1 3RH 0.0000000359 0.47623 22.6837
158 5UR1 YY9 0.00003314 0.43934 23.1511
159 3LXN MI1 0.0000001277 0.64887 23.2704
160 4IX4 ADP 0.0000002973 0.42127 23.4756
161 2XVD AS6 0.000003925 0.54275 23.5099
162 5JKG 6LF 0.00008883 0.41489 23.7942
163 3I7V B4P 0.005936 0.44549 23.8806
164 3SLS ANP 0.000000186 0.6342 24.0132
165 3SLS 77D 0.01206 0.42356 24.0132
166 4E1Z 0MX 0.0000003294 0.61629 24.3986
167 4GJ3 0XP 0.00000008081 0.60112 24.5033
168 5IQD RIO 0.000004243 0.45486 24.918
169 5IQD GNP 0.000003618 0.45371 24.918
170 4XH0 ADP 0.00001377 0.61369 25
171 3G5D 1N1 0.00000006923 0.54616 25.1748
172 4YMJ 4EJ 0.000000919 0.68177 25.3289
173 5T8O 76Z 0.00000002548 0.68144 25.6098
174 3ALN ANP 0.0000006589 0.61571 25.6881
175 4AG8 AXI 0.00002378 0.48826 25.9494
176 3VRY B43 0.00005253 0.50856 26.2195
177 4IDT T28 0.0000001187 0.67423 26.5244
178 2CSN CKI 0.000176 0.43576 26.936
179 5LXC 7AA 0.000000009569 0.42323 27.439
180 5HX8 66P 0.00000112 0.57548 27.4834
181 2F57 23D 0.00001113 0.58363 28.0757
182 5AWM ANP 0.000005 0.61664 28.3537
183 3GC0 AMP 0.000001286 0.63905 29.2683
184 5LI9 ACP 0.000001115 0.61178 29.2683
185 5LI1 ANP 0.00000002487 0.45069 29.2683
186 4BTK DTQ 0.0000001023 0.4286 29.2683
187 4H3P ANP 0.000000004715 0.73364 29.5732
188 5LPZ ADP 0.000000006649 0.72642 29.5732
189 5BYZ 4WE 0.00000009471 0.59837 29.5732
190 4WHZ 3NL 0.000005274 0.47699 29.5732
191 4H3Q ANP 0.0000000254 0.46164 29.5732
192 2WU6 DKI 0.000000008834 0.68677 29.878
193 5BVE 4VG 0.0000003027 0.47143 29.878
194 4AUA 4AU 0.0000007709 0.63413 29.9674
195 3PVW QRX 0.000001344 0.5721 30.1829
196 4YLL 4E3 0.000000245 0.44297 30.1829
197 5UKL SIX 0.00002426 0.40841 30.1829
198 3UIM ANP 0.00000004351 0.68696 30.3681
199 4FL3 ANP 0.0000000165 0.68223 30.4878
200 3GC8 B45 0.000001058 0.59972 30.4878
201 1CM8 ANP 0.0000004141 0.40829 30.4878
202 3KRR DQX 0.0000001388 0.54467 30.5085
203 5X8I SQZ 0.0000000021 0.75063 31.0976
204 4QTB 38Z 0.00000005504 0.47943 31.0976
205 5HCY 60D 0.00000003139 0.56463 31.4024
206 3VHE 42Q 0.000005867 0.53115 31.4763
207 4NST ADP 0.0000008256 0.62513 31.7073
208 4NST AF3 0.000001572 0.54902 31.7073
209 3C1X CKK 0.0002649 0.49017 31.7073
210 2HK5 1BM 0.0000004924 0.41568 31.8519
211 2JLD AG1 0.0000000001241 0.69958 32.0122
212 4CRL C1I 0.0000003652 0.56539 32.0122
213 5LXT ACP 0.001995 0.44666 32.1678
214 4E93 GUI 0.0000001581 0.58439 32.622
215 5LPB ADP 0.00000184 0.63951 32.7703
216 5HQ0 LZ9 0.00000004148 0.67159 32.7815
217 1U5R ATP 0.00000008029 0.67409 32.9268
218 5EFQ ADP 0.0000002635 0.64912 32.9268
219 3PP0 03Q 0.0000116 0.53226 32.9268
220 1OUK 084 0.00001004 0.50588 32.9268
221 4CLI 5P8 0.000002556 0.47657 33.3333
222 3LXK MI1 0.0000005912 0.58186 33.6391
223 4AU8 Z3R 0.000004255 0.62034 33.7838
224 2OO8 RAJ 0.0008298 0.46752 34.0694
225 5JFS 6K0 0.00001953 0.43911 34.0909
226 1UNH IXM 0.0000002102 0.67957 34.2466
227 3O0G 3O0 0.00000002049 0.42785 34.2466
228 1V0O INR 0.0000001429 0.65411 35.0694
229 3GQI ACP 0.00000001713 0.70654 35.2761
230 5TA6 79D 0.000002193 0.55803 35.3659
231 3TXO 07U 0.000000003917 0.43025 35.3659
232 5HES 032 0.000003438 0.40047 35.5049
233 3TTI KBI 0.00000005664 0.6245 35.6707
234 4Y93 746 0.000005771 0.55009 35.6707
235 5U6C 7YS 0.0000005739 0.61185 35.873
236 2BPM 529 0.0000000004513 0.60823 35.9223
237 1OPK P16 0.00011 0.47609 35.9756
238 3SRV S19 0.000000005421 0.43385 36.1011
239 4UX9 ANP 0.0000000273 0.68004 36.2805
240 4IZY 1J2 0.000000217 0.63815 36.2805
241 3KRL KRL 0.000007114 0.56192 36.2805
242 4CFU 2WC 0.00000000946 0.73842 36.3036
243 4BCM T7Z 0.000001476 0.66349 36.5448
244 3BU5 ATP 0.0000000186 0.43644 36.6013
245 4F4P 0SB 0.00000006754 0.55038 36.63
246 4BCN T9N 0.000000009942 0.74784 36.6667
247 5EOB 5QQ 0.0001016 0.44077 36.6771
248 5KO1 6UY 0.000005562 0.59176 36.7491
249 4QMN DB8 0.0000003213 0.55845 36.7742
250 3EKK GS2 0.000001765 0.52672 36.8078
251 5JGA 6KC 0.0000002759 0.5749 36.8254
252 5LMK 6ZK 0.0000001138 0.40467 37.037
253 1XJD STU 0.000000002772 0.73531 37.1951
254 3E7O 35F 0.00002276 0.49962 37.1951
255 2XMY CDK 0.00000258 0.50292 37.2483
256 1PHK ATP 0.000000002934 0.45922 37.2483
257 2B9I ADP 0.0000002428 0.65084 37.3938
258 2B9J ADP 0.0000004178 0.64726 37.3938
259 2B9H ADP 0.0000001048 0.43399 37.3938
260 3NW7 LGV 0.0001523 0.42579 37.4593
261 4P5Z Q7M 0.00001622 0.48774 37.5
262 2V7O DRN 0.000000005184 0.40211 37.5
263 2B9F ADP 0.000000344 0.4177 37.6771
264 5NKB 8ZT 0.000004441 0.49793 37.9085
265 3PLS ANP 0.00000002315 0.70928 37.9195
266 3IGO ANP 0.0000008322 0.60448 38.1098
267 1K3A ACP 0.000001236 0.63995 38.1271
268 4U0I 0LI 0.0002469 0.46209 38.4127
269 3F7Z 34O 0.000000001283 0.45733 38.4146
270 3ZRM ZRM 0.0000002016 0.41763 38.4146
271 3HMO STU 0.0000001627 0.66747 38.7195
272 4NM5 ADP 0.0000006393 0.60337 38.7195
273 4WB7 ATP 0.0000002848 0.56042 38.7195
274 4WB6 ATP 0.00000001076 0.48077 38.7195
275 4WNK 453 0.0000001655 0.59396 39.0244
276 4OTH DRN 0.000000000769 0.74305 39.3293
277 2PVF ACP 0.00000001608 0.71709 39.3293
278 1U59 STU 0.00000001924 0.7041 39.3728
279 1JPA ANP 0.00004688 0.57289 39.7436
280 4KBA 1QM 0.000001588 0.56389 39.8792
281 4I6H 1C8 0.0001835 0.51161 39.9351
282 5N87 N66 0.0000009914 0.54007 40.2556
283 2A19 ANP 0.0000002823 0.68241 40.493
284 2GU8 796 0.000000007653 0.53627 40.5488
285 2Y6O 1N1 0.000002965 0.57928 40.8935
286 1BYG STU 0.0000005714 0.64864 41.0072
287 4EWH T77 0.0000002139 0.60034 41.0909
288 3IDB ANP 0.000000008723 0.68701 41.1585
289 1RE8 BD2 0.0000000001502 0.61581 41.1585
290 3SXF BK5 0.00001257 0.50224 41.1585
291 2QCS ANP 0.000000006669 0.4857 41.1585
292 3FHI ANP 0.00000001239 0.48093 41.1585
293 2VZ6 FEF 0.000001962 0.6296 41.2141
294 4ASE AV9 0.00004592 0.50272 41.7683
295 4FG8 ATP 0.0000002718 0.42938 41.9048
296 5H2U 1N1 0.0004238 0.49402 41.9476
297 4BHN BH9 0.0000001997 0.63983 42.0732
298 5DA3 58V 0.00001407 0.59297 42.2642
299 4L9I 8PR 0.00003399 0.55295 42.378
300 5TO8 7FM 0.000008357 0.49485 42.5532
301 3SXS PP2 0.00001723 0.54976 42.9104
302 2OFV 242 0.00001261 0.49861 42.9603
303 4XLI 1N1 0.000001301 0.62291 43.2836
304 2WEI VGG 0.00003385 0.55929 43.554
305 3HZT J60 0.000001392 0.64591 43.5976
306 4CSV STI 0.0000545 0.51679 43.6364
307 3BZ3 YAM 0.00002122 0.43698 43.8406
308 4TWP AXI 0.0000158 0.46984 43.9114
309 5FBN 5WF 0.000007509 0.44102 43.9114
310 2ZV2 609 0.0000003296 0.67887 44.2953
311 5UOX 8GY 0.00000005316 0.65903 44.6494
312 4D2S DYK 0.0000025 0.62418 44.7183
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