Receptor
PDB id Resolution Class Description Source Keywords
1ZC3 2 Å NON-ENZYME: SIGNAL_HORMONE CRYSTAL STRUCTURE OF THE RAL-BINDING DOMAIN OF EXO84 IN COMPLEX WITH THE ACTIVE RALA HOMO SAPIENS EXOCYTOSIS SMALL GTPASE GTP-BINDING PROTEIN SIGNALING PROTEIN
Ref.: EXO84 AND SEC5 ARE COMPETITIVE REGULATORY SEC6/8 EFFECTORS TO THE RALA GTPASE. EMBO J. V. 24 2064 2005
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GNP A:700;
C:800;
Valid;
Valid;
none;
none;
submit data
522.196 C10 H17 N6 O13 P3 c1nc2...
MG A:500;
C:600;
Part of Protein;
Part of Protein;
none;
none;
submit data
24.305 Mg [Mg+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1ZC3 2 Å NON-ENZYME: SIGNAL_HORMONE CRYSTAL STRUCTURE OF THE RAL-BINDING DOMAIN OF EXO84 IN COMPLEX WITH THE ACTIVE RALA HOMO SAPIENS EXOCYTOSIS SMALL GTPASE GTP-BINDING PROTEIN SIGNALING PROTEIN
Ref.: EXO84 AND SEC5 ARE COMPETITIVE REGULATORY SEC6/8 EFFECTORS TO THE RALA GTPASE. EMBO J. V. 24 2064 2005
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 263 families.
1 1ZC4 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
2 1ZC3 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 196 families.
1 1ZC4 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
2 1ZC3 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
50% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 171 families.
1 1ZC4 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
2 1ZC3 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GNP; Similar ligands found: 128
No: Ligand ECFP6 Tc MDL keys Tc
1 GNP 1 1
2 GDP 0.839506 0.973684
3 GP3 0.82716 0.948718
4 GTP 0.809524 0.973684
5 GNH 0.807229 0.986842
6 G1R 0.77907 0.961039
7 GCP 0.77907 0.948718
8 GSP 0.770115 0.925
9 5GP 0.756098 0.960526
10 G 0.756098 0.960526
11 G2R 0.747253 0.936709
12 GMV 0.747126 0.948718
13 GAV 0.714286 0.936709
14 GP2 0.712644 0.936709
15 G2P 0.711111 0.936709
16 Y9Z 0.708333 0.880952
17 GDP MG 0.696629 0.9
18 GDD 0.690722 0.936709
19 GDC 0.690722 0.936709
20 GKE 0.690722 0.936709
21 GDP BEF 0.688889 0.878049
22 G5P 0.686869 0.948718
23 GPG 0.684211 0.936709
24 GTG 0.683673 0.91358
25 GFB 0.683673 0.936709
26 GDR 0.683673 0.936709
27 JB2 0.68 0.936709
28 GKD 0.68 0.936709
29 G3A 0.676768 0.948718
30 6CK 0.676768 0.91358
31 GDX 0.673267 0.948718
32 ALF 5GP 0.67033 0.86747
33 GTP MG 0.666667 0.9
34 BEF GDP 0.666667 0.86747
35 YGP 0.663265 0.879518
36 GCP G 0.659574 0.911392
37 GPD 0.656863 0.902439
38 GDP AF3 0.645833 0.86747
39 GDP ALF 0.645833 0.86747
40 JB3 0.641509 0.925
41 DBG 0.640351 0.974359
42 G3D 0.638298 0.960526
43 G4P 0.625 0.960526
44 GMP 0.621951 0.857143
45 NGD 0.62037 0.936709
46 GGM 0.618182 0.925926
47 0O2 0.616162 0.960526
48 G G 0.61 0.911392
49 2MD 0.603604 0.870588
50 CAG 0.60177 0.904762
51 U2G 0.590909 0.91358
52 FEG 0.590909 0.858824
53 GDP 7MG 0.590476 0.888889
54 MGD 0.587719 0.870588
55 ZGP 0.585586 0.848837
56 CG2 0.580357 0.91358
57 ANP 0.568421 0.922078
58 PGD 0.567797 0.902439
59 MD1 0.567797 0.870588
60 3GP 0.56044 0.922078
61 TPG 0.558333 0.822222
62 GH3 0.55 0.948052
63 FE9 0.546219 0.778947
64 GPX 0.539216 0.922078
65 G4M 0.539062 0.860465
66 DGI 0.536082 0.9
67 BGO 0.535088 0.901235
68 IDP 0.53125 0.947368
69 DGT 0.53 0.9
70 2GP 0.526882 0.935065
71 G1R G1R 0.520325 0.901235
72 I2C FE2 CMO CMO 0.516667 0.811111
73 U A G G 0.512605 0.911392
74 AGO 0.504202 0.91358
75 G A A A 0.504202 0.9
76 P2G 0.5 0.860759
77 G1G 0.5 0.902439
78 MGP 0.49505 0.936709
79 PGD O 0.492063 0.831461
80 6G0 0.490196 0.936709
81 P1G 0.489796 0.85
82 DGP 0.474227 0.8875
83 DG 0.474227 0.8875
84 G G U 0.473684 0.911392
85 IMP 0.463918 0.934211
86 G2Q 0.462963 0.936709
87 GPC 0.459677 0.858824
88 G C 0.459016 0.878049
89 GTA 0.448276 0.91358
90 G7M 0.444444 0.924051
91 MAP 0.439252 0.898734
92 G G G RPC 0.435484 0.853659
93 B4P 0.434343 0.871795
94 AP5 0.434343 0.871795
95 ADP 0.434343 0.896104
96 A2D 0.43299 0.871795
97 U G A 0.431655 0.86747
98 G G G C 0.426357 0.890244
99 SGP 0.425743 0.807229
100 AU1 0.425743 0.922078
101 BA3 0.424242 0.871795
102 35G 0.423077 0.909091
103 PCG 0.423077 0.909091
104 A G C C 0.423077 0.888889
105 C2E 0.423077 0.897436
106 APC G U 0.421875 0.864198
107 ATP 0.421569 0.896104
108 ACQ 0.419048 0.873418
109 5GP 5GP 0.419048 0.860759
110 AQP 0.417476 0.896104
111 5FA 0.417476 0.896104
112 01G 0.417391 0.880952
113 UNP 0.415842 0.810127
114 AN2 0.415842 0.909091
115 6AD 0.415094 0.821429
116 ITT 0.411765 0.846154
117 M33 0.411765 0.860759
118 G C C C 0.410448 0.901235
119 G U34 0.408 0.86747
120 ACP 0.407767 0.873418
121 APR 0.403846 0.871795
122 AR6 0.403846 0.871795
123 DG DG 0.403509 0.845238
124 A4P 0.403226 0.848837
125 UCG 0.402985 0.888889
126 AD9 0.4 0.873418
127 SAP 0.4 0.851852
128 AGS 0.4 0.851852
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1ZC3; Ligand: GNP; Similar sites found: 455
This union binding pocket(no: 1) in the query (biounit: 1zc3.bio1) has 27 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1UPT GTP 0.0000000002241 0.72315 None
2 3BFV ADP 0.00003306 0.54492 None
3 3BIB PSF 0.02503 0.40552 None
4 2IL4 COA 0.01536 0.40141 None
5 4WOP CTP 0.0001102 0.48536 1.71429
6 1P9B GDP 0.0001612 0.48794 1.76991
7 1P9B HDA 0.02998 0.40663 1.76991
8 4GOX A3P 0.001752 0.42598 2.28571
9 1XP8 AGS 0.0004157 0.49646 2.65487
10 1GOJ ADP 0.0000005178 0.67708 2.85714
11 1WY7 SAH 0.007393 0.40279 2.85714
12 1CR1 TTP 0.001044 0.40075 2.85714
13 2XT3 ADP 0.000002383 0.63335 3.42857
14 4U00 ADP 0.000007471 0.6138 3.42857
15 4CVN ADP 0.00000804 0.59242 3.42857
16 2ZFI ADP 0.00000505 0.58541 3.42857
17 1L2T ATP 0.0008882 0.43471 3.42857
18 3BER AMP 0.01209 0.41761 3.42857
19 4C2C ALA ALA ALA 0.01204 0.41198 3.42857
20 4X1Z FUC GAL NDG 0.0323 0.41119 3.42857
21 5VGR GDP 0.0004275 0.46875 3.53982
22 1LVG ADP 0.000002688 0.42081 3.53982
23 4RD0 GDP 0.000000000122 0.7344 4
24 4WZ6 ATP 0.00001891 0.58046 4
25 5G41 AP5 0.003254 0.42616 4
26 1M7G ADX 0.00175 0.42232 4.42478
27 2PEZ DAT 0.002139 0.42017 4.42478
28 1M7G ADP 0.002678 0.41203 4.42478
29 5J6Y BGC 0.0233 0.41191 4.42478
30 5J6Y GLC 0.0233 0.41191 4.42478
31 1M7G AV2 0.00001831 0.41143 4.42478
32 1BO4 COA 0.02679 0.4003 4.42478
33 1KK1 GNP 0.000000004495 0.74908 4.57143
34 3A1S GDP 0.000000005105 0.72256 4.57143
35 2OBM ADP 0.0003504 0.51414 4.57143
36 1D2N ANP 0.0005951 0.45353 4.57143
37 2Q37 3AL 0.01636 0.42134 4.57143
38 5VYQ FON 0.01381 0.41079 4.57143
39 5IFS ADP 0.0001695 0.40341 4.57143
40 1JI0 ATP 0.00004764 0.55208 5.14286
41 5I34 GDP 0.00005494 0.52722 5.14286
42 3H86 AP5 0.002921 0.41725 5.14286
43 2TOH HBI 0.02777 0.40915 5.14286
44 1P4V GLY 0.03716 0.40122 5.14286
45 2QZ4 ADP 0.00007905 0.51338 5.30973
46 3ZS9 ADP ALF 0.00002049 0.49261 5.30973
47 2WOJ ADP ALF 0.00002446 0.48957 5.30973
48 1IN4 ADP 0.0002941 0.47136 5.30973
49 4R2I ANP 0.002746 0.46014 5.30973
50 1VHT BA3 0.001314 0.45558 5.30973
51 1QHG ATP 0.00385 0.42935 5.30973
52 1PZM 5GP 0.01021 0.42562 5.30973
53 5X40 ACP 0.000923 0.41262 5.30973
54 2VVG ADP 0.0000005463 0.40537 5.30973
55 5J1J ANP 0.00001296 0.51501 5.61404
56 3PQC GDP 0.00000002723 0.67732 5.71429
57 2OZE AGS 0.00004271 0.50853 5.71429
58 1G41 ADP 0.0001274 0.50356 5.71429
59 3BP1 GUN 0.01369 0.42161 5.71429
60 2BIF ANP 0.00351 0.41274 5.71429
61 2BIF SIN 0.00609 0.41274 5.71429
62 1IG3 VIB 0.02331 0.4002 5.71429
63 2BVE PH5 0.04294 0.40808 5.88235
64 2ZTS ADP 0.00157 0.43908 5.9761
65 1T5C ADP 0.000005917 0.61715 6.19469
66 4KFU ACP 0.00003034 0.56812 6.19469
67 1OXV ANP 0.00006729 0.53669 6.19469
68 2B8W ALF 5GP 0.00001325 0.50957 6.19469
69 5BQ5 ADP BEF 0.0001089 0.50678 6.19469
70 3ZFD ANP 0.0000001771 0.50281 6.19469
71 1NY5 ADP 0.000865 0.45488 6.19469
72 5MEX PAP 0.00643 0.41187 6.19469
73 1DQN IMU 0.02895 0.40239 6.19469
74 2CE7 ADP 0.000164 0.40211 6.19469
75 3CNL GNP 0.000000004939 0.74699 6.28571
76 3VX3 ADP 0.00003963 0.50998 6.28571
77 3KTA AP5 0.0007256 0.46294 6.28571
78 4FUA PGH 0.01583 0.42028 6.28571
79 4QM7 GTP 0.00009198 0.52287 6.43275
80 2QN6 GDP 0.0000000005941 0.79378 6.45161
81 1SVI GDP 0.0000000004744 0.79875 6.85714
82 4NON GDP 0.00000004454 0.5865 6.85714
83 4P4T GDP 0.000001012 0.58063 6.85714
84 4E03 ADP 0.000007994 0.56778 6.85714
85 2IS6 ADP 0.0001083 0.51936 6.85714
86 4C25 13P 0.005628 0.43883 6.85714
87 4OI4 ATP 0.001827 0.42521 6.85714
88 5AHO TLA 0.01158 0.41554 6.85714
89 2WJG GDP 0.000000004837 0.7352 7.07965
90 3DC4 ADP 0.000003842 0.60916 7.07965
91 3EZ2 ADP 0.00002035 0.56311 7.07965
92 4V03 ADP 0.000008088 0.56025 7.07965
93 3FKQ ATP 0.00001265 0.53801 7.07965
94 4RZ3 ADP 0.00002875 0.52186 7.07965
95 1R6B ADP 0.0001444 0.50688 7.07965
96 4R43 GDP 0.000328 0.49547 7.07965
97 5K5Z ANP 0.00003436 0.49262 7.07965
98 4TTQ ATP 0.000378 0.49241 7.07965
99 2BEK ATP 0.00008242 0.48605 7.07965
100 4YS0 ADP 0.001109 0.44998 7.07965
101 4OHY ANP 0.0004 0.44892 7.07965
102 3VM7 GLC 0.009836 0.44645 7.07965
103 2J5V PCA 0.02387 0.43079 7.07965
104 4FRZ ADP 0.000008197 0.40215 7.07965
105 2WJH GDP 0.00000001072 0.53577 7.22892
106 2WJH FLC 0.0000005141 0.48963 7.22892
107 5HCN GCP 0.0000000005504 0.76943 7.42857
108 1TAD GDP 0.0000000001819 0.66717 7.42857
109 1TAD ALF 0.0000000001819 0.66717 7.42857
110 4D81 ADP 0.0001651 0.49271 7.42857
111 5HR5 ADP 0.0008217 0.45589 7.42857
112 2X7I CIT 0.003123 0.44688 7.42857
113 4KVA GTP 0.00004881 0.40976 7.42857
114 1LOB MMA 0.03076 0.40727 7.42857
115 3AB4 THR 0.02215 0.40445 7.42857
116 1D2E GDP 0.000000009792 0.6884 7.9646
117 5KSZ GCP 0.000000151 0.6421 7.9646
118 2NCD ADP 0.000009261 0.59583 7.9646
119 4LYA ATP 0.00002196 0.54652 7.9646
120 4MKG AP5 0.002898 0.42319 7.9646
121 3QOX SAH 0.00207 0.40632 7.9646
122 1KO8 6PG 0.0006148 0.40382 7.9646
123 4ZNL BEF ADP 0.0003044 0.4912 8
124 4LJ9 ACP 0.001271 0.46627 8
125 2XAU ADP 0.001393 0.45436 8
126 4PJ3 ANP 0.002723 0.43633 8
127 3S6X SIA GAL BGC 0.02614 0.41179 8
128 3RK0 AMP 0.01966 0.40329 8
129 2AWN ADP 0.0000006785 0.68396 8.57143
130 1JWY GDP 0.000000155 0.63287 8.57143
131 5I0H ADP BEF 0.000001624 0.56496 8.57143
132 1JWY ADP 0.00001307 0.55743 8.57143
133 3T1O GDP 0.000000017 0.5381 8.57143
134 1XMV ADP 0.0002767 0.4932 8.57143
135 3FVQ ATP 0.0001997 0.47414 8.57143
136 5XDR ADP 0.001268 0.46117 8.57143
137 3RLF ANP 0.0003122 0.45728 8.57143
138 3WYA GDP 0.00000000008552 0.82216 8.84956
139 4B47 GDP 0.0000000002093 0.81683 8.84956
140 3WY9 GDP 0.0000000002471 0.81317 8.84956
141 5KSP GDP 0.00000004964 0.6747 8.84956
142 5IRR GSP 0.000000008242 0.65645 8.84956
143 1TQ4 GDP 0.00000001494 0.65346 8.84956
144 1WDT GTP 0.00000003364 0.64621 8.84956
145 2FAH GDP 0.0001933 0.48954 8.84956
146 1YXM ADE 0.00338 0.45953 8.84956
147 4IOK XPO 0.001565 0.42462 8.84956
148 1FNZ A2G 0.01578 0.42056 8.84956
149 2GWH A3P 0.008765 0.40923 8.84956
150 4IOK ADP 0.002018 0.40887 8.84956
151 5TSH ADP 0.00007196 0.54753 9.14286
152 5TSH ANP 0.00006321 0.53096 9.14286
153 1XKV ATP 0.0003089 0.48535 9.14286
154 4QRH 0O2 0.005178 0.41265 9.14286
155 5H56 TYD 0.002823 0.41255 9.14286
156 5H56 ADP 0.002823 0.41255 9.14286
157 1OFH ADP 0.0001597 0.40605 9.1954
158 5TQZ GLC 0.01313 0.42959 9.33333
159 3NHB ADP 0.00002478 0.57396 9.71429
160 1G6O ADP 0.0003104 0.48525 9.71429
161 1YTM ATP 0.0003572 0.46316 9.71429
162 3QKT ANP 0.001457 0.42589 9.71429
163 3SJK LYS PRO VAL LEU ARG THR ALA 0.02758 0.41308 9.71429
164 3QXC ATP 0.004029 0.40197 9.71429
165 2RCN GDP 0.00000000005622 0.8312 9.73451
166 4M9Q GNP 0.00000000009337 0.73935 9.73451
167 4ZG4 VO4 ADP 0.000002689 0.54355 9.73451
168 3UIE ANP 0.00007618 0.51414 9.73451
169 2JLR ANP 0.0002396 0.48522 9.73451
170 2QEN ADP 0.00006529 0.43295 9.73451
171 4Z7X 3CX 0.03743 0.40722 9.73451
172 1OBV FMN 0.009388 0.40138 9.73451
173 1GXU 2HP 0.0003165 0.49294 9.89011
174 5GVR LMR 0.000258 0.51982 10.2857
175 1QHH ATP 0.009249 0.41927 10.4348
176 2C78 GNP 0.0000000002398 0.7219 10.6195
177 2C77 GNP 0.0000000004072 0.72146 10.6195
178 1SVK ALF GDP 0.0000000001169 0.70867 10.6195
179 2OM2 GDP 0.0000001485 0.61012 10.6195
180 2IYL GDP 0.000007645 0.57648 10.6195
181 2WHX ADP 0.00003099 0.56841 10.6195
182 3T34 GDP 0.000002005 0.54888 10.6195
183 4WZA ACP 0.00001213 0.54345 10.6195
184 4WZA ADP 0.00001219 0.54335 10.6195
185 4YMU ATP 0.00006575 0.5372 10.6195
186 5IRN ADP 0.0001274 0.49793 10.6195
187 1U0J ADP 0.0009045 0.47927 10.6195
188 4Y4V DAL 0.006607 0.43606 10.6195
189 5FJJ MAN 0.02357 0.42824 10.6195
190 4MKF AP5 0.002672 0.42574 10.6195
191 3QF7 ANP 0.002568 0.4156 10.6195
192 4PU6 ASP 0.03157 0.40444 10.6195
193 5GOE GDP 0.000000004885 0.71264 10.8571
194 4BAS GNP 0.000000001022 0.62622 10.8571
195 5M7P ADP 0.001092 0.44608 10.8571
196 2Q2Y MKR 0.00112 0.43923 10.8571
197 2Q2Y ADP 0.001195 0.43923 10.8571
198 3BFX A3P 0.004729 0.41781 10.8571
199 1RZU ADP 0.02379 0.4029 10.8571
200 1F2U ATP 0.002629 0.40931 11.4094
201 3U6B GDP 0.0000000002425 0.81358 11.4286
202 1D8T GDP 0.0000000007364 0.77577 11.4286
203 5JBQ GDP 0.0000000007688 0.77484 11.4286
204 4G5G GDP 0.0000000008409 0.77291 11.4286
205 2BVN GNP 0.0000000002295 0.76387 11.4286
206 3U6K GDP 0.000000001445 0.76124 11.4286
207 4PC3 GDP 0.00000005751 0.6528 11.4286
208 4P3Y GDP 0.0000000003547 0.54188 11.4286
209 2FNA ADP 0.0001921 0.47039 11.4286
210 4U60 SIA GAL NGA 0.01597 0.42951 11.4286
211 4U60 SIA 0.01614 0.42946 11.4286
212 2W58 ADP 0.0000004068 0.69214 11.5044
213 1V8K ANP 0.0000002412 0.65096 11.5044
214 3FWY ADP 0.000002751 0.56803 11.5044
215 3B5J 12D 0.0000433 0.55425 11.5044
216 3BOS CDP 0.0002488 0.50143 11.5044
217 2GK6 ADP 0.001394 0.47553 11.5044
218 5H68 AGS 0.001146 0.40189 11.5044
219 2CBZ ATP 0.000001626 0.65411 12
220 2HF9 GSP 0.0000000969 0.63387 12
221 1YQT ADP 0.00003787 0.5645 12
222 2D2F ADP 0.0002888 0.51522 12
223 2C9O ADP 0.0002345 0.47111 12
224 3IO3 ADP 0.00003939 0.44749 12.3563
225 1Y63 ADP 0.00001784 0.55822 12.3894
226 4HSE ADP 0.00003974 0.53404 12.3894
227 4IHQ ADP 0.000295 0.50403 12.3894
228 4QOS ADP 0.0007787 0.46634 12.3894
229 1QAN SAH 0.00152 0.42855 12.3894
230 5A7Y SAH 0.01807 0.41293 12.3894
231 5KXE 6Y2 0.02842 0.40945 12.3894
232 3H4S ADP 0.000002319 0.4033 12.3894
233 4XTR ADP 0.00003737 0.51111 12.5714
234 4XVU ATP 0.0000423 0.49355 12.5714
235 4XTR ATP 0.00004269 0.49339 12.5714
236 1W0J ADP 0.0001771 0.41252 12.5714
237 1W0J ADP BEF 0.0004321 0.40985 12.5714
238 1F9V ADP 0.000008171 0.40349 12.5714
239 4PPF FLC 0.00001502 0.59197 13.1429
240 4H1V GNP 0.0000009078 0.58985 13.1429
241 2VB6 ADP BEF 0.00006197 0.48662 13.1429
242 4PFO ADP 0.0001596 0.45244 13.1429
243 5H67 ATP 0.004688 0.43362 13.1429
244 5J1S ATP 0.003053 0.41272 13.1429
245 1W7J ADP BEF 0.0000194 0.5296 13.245
246 5N69 ADP 0.0000217 0.53351 13.2743
247 1IHU AF3 0.00001807 0.51413 13.2743
248 3ZQ6 ADP ALF 0.00000664 0.51194 13.2743
249 1IHU ADP 0.00002296 0.50464 13.2743
250 3KJI ADP 0.00001319 0.45581 13.2743
251 1W5T ANP 0.000588 0.45376 13.2743
252 1W5T ADP 0.00109 0.45033 13.2743
253 4Z2S NDG 0.02485 0.41305 13.3803
254 4Z2S NAG 0.02485 0.41305 13.3803
255 1FQJ ALF 0.0000002118 0.68308 13.6054
256 1FQK ALF 0.0000003401 0.67947 13.6054
257 1FQJ GDP 0.000000004418 0.65988 13.6054
258 1FQK GDP 0.00000001161 0.64235 13.6054
259 4J0Q GDP 0.0000000009389 0.78367 13.7143
260 1G8S MET 0.01951 0.4185 13.7143
261 2GUC MAN 0.02213 0.40945 13.9344
262 2GUD BMA 0.02407 0.40528 13.9344
263 2GUD MAN 0.0257 0.4033 13.9344
264 2CK3 ANP 0.0004423 0.4635 14
265 2CK3 ADP 0.0006315 0.4445 14
266 4PX9 ADP 0.0001076 0.52631 14.1593
267 1Z6T ADP 0.000177 0.4861 14.1593
268 3B7G ANP 0.000903 0.46831 14.1593
269 1B0U ATP 0.001031 0.45586 14.1593
270 2D7I NGA 0.02245 0.41228 14.1593
271 2F5X ASP 0.04012 0.40003 14.1593
272 5MVR ADP 0.00009921 0.52124 14.1975
273 2ODE ALF GDP 0.0000000001191 0.67405 14.2857
274 4HI0 GDP 0.0000001022 0.61717 14.2857
275 5LB3 ADP 0.0002056 0.51201 14.2857
276 2IXE ATP 0.000665 0.44741 14.2857
277 1G7S GDP 0.000000005888 0.71956 14.8571
278 2DPY ADP 0.0002122 0.51821 14.8571
279 5LTJ ADP 0.0003257 0.48977 14.8571
280 2VF7 ADP 0.0007104 0.47336 14.8571
281 1G7C 5GP 0.0000005373 0.6337 14.8936
282 3LRE ADP 0.000001269 0.65254 15.0442
283 4AG5 ADP 0.00001251 0.58902 15.0442
284 1FP6 ADP 0.000003985 0.56759 15.0442
285 1GOT GDP 0.00000007402 0.61584 15.0685
286 3CM2 X23 0.03077 0.40731 15.3846
287 4DCT GDP 0.0000000003206 0.7808 15.4286
288 4LPS GDP 0.00000001563 0.69901 15.4286
289 1JJ7 ADP 0.000003171 0.63768 15.4286
290 2HCJ GDP 0.0000000002182 0.54598 15.9292
291 4BQS ADP 0.00005297 0.53476 15.9292
292 3W5J GDP 0.000003061 0.62237 16
293 4YDS ATP 0.00002959 0.56288 16
294 4NCN GTP 0.00000000004918 0.74149 16.5714
295 4TMZ GSP 0.0000000001331 0.72343 16.5714
296 1DAR GDP 0.00000003152 0.69482 16.5714
297 2CHG ANP 0.0002089 0.48284 16.5714
298 3RC3 ANP 0.01569 0.41608 16.5714
299 2V7Q ADP 0.00007203 0.52814 16.6667
300 2V7Q ATP 0.0001367 0.50212 16.6667
301 5C2N NAG 0.02949 0.40665 16.6667
302 3PCR GTP 0.0000000005076 0.69914 16.8142
303 3Q9L ATP 0.00003085 0.52047 16.8142
304 4P32 ADP 0.003701 0.41562 16.8142
305 2PNZ 5GP 0.01954 0.4153 16.8142
306 1NJF AGS 0.0001082 0.44314 17.1429
307 1NJF ADP 0.0001014 0.43176 17.1429
308 5KDO GDP 0.0000001399 0.61124 17.5676
309 1AZT GSP 0.0000000001138 0.67488 17.6991
310 1CS4 GSP 0.0000000006572 0.65801 17.6991
311 5GJC ATP 0.0000618 0.53144 17.6991
312 3TBK ANP 0.0005698 0.49582 17.6991
313 2IDO TMP 0.0332 0.40438 17.6991
314 5FG3 GDP 0.0000000001195 0.82921 17.7143
315 4XGU ADP 0.0002383 0.48025 17.7143
316 2GJ8 ALF GDP 0.000000001425 0.65684 18.0233
317 2XTZ GSP 0.000000000103 0.7103 18.2857
318 1GP2 GDP 0.0000002115 0.58969 18.3099
319 2GDJ ANP 0.0001886 0.5074 18.5841
320 3FYH ADP 0.003915 0.40828 18.5841
321 2ZR9 DTP 0.0002293 0.50318 18.8571
322 3A4M ADP 0.000007945 0.59269 19.4286
323 3IIJ ADP 0.0000142 0.56313 19.4286
324 3TK1 GDP 0.0000000004474 0.81452 19.469
325 5FTB ANP 0.0001995 0.49434 19.469
326 4R98 GNH 0.0000002547 0.64978 19.5572
327 1KK8 BEF ADP 0.00001561 0.53388 20
328 1B7T ADP 0.00003111 0.53255 20
329 5MZN ADP 0.001294 0.47722 20
330 3VMF GTP 0.000000000741 0.65928 20.354
331 3WXM GTP 0.0000000008387 0.65726 20.354
332 5FHD ADP ALF 0.0004714 0.45793 20.354
333 1SQ5 ADP 0.00006982 0.52218 20.5714
334 2WIC GNP 0.000000005811 0.71983 20.5993
335 1G6H ADP 0.000004246 0.62966 21.2389
336 4CP8 MLI 0.03698 0.40251 21.7143
337 4ZKD GDP 0.000000002673 0.64605 22.1239
338 4LC1 GDP 0.000000004863 0.73509 22.2857
339 3COB ADP 0.000001522 0.40803 22.2857
340 3EC1 GDP 0.00000001021 0.53019 22.8571
341 4A4Z ANP 0.005284 0.43552 22.8571
342 4IEE AGS 0.0006502 0.48657 23.0089
343 3T12 GDP ALF 0.0000000005362 0.70701 23.8938
344 2ZPA ADP 0.0003962 0.40964 24.5714
345 1OYY AGS 0.00101 0.47123 24.7788
346 4ZI2 GNP 0.0000000001413 0.73168 25.1429
347 4GOJ GNP 0.0000000001186 0.65954 25.1429
348 4IDN GNP 0.00008934 0.48455 25.1429
349 4KBF AMP 0.002118 0.46046 25.6637
350 4V0K GDP 0.0000001027 0.59609 26.0355
351 2XTN GTP 0.0000002732 0.58504 26.2857
352 3MD0 GDP 0.000000001751 0.76991 26.5487
353 1SKQ GDP 0.00000001014 0.73109 26.5487
354 1H65 GDP 0.000001116 0.56565 26.5487
355 3ZIA ATP 0.00007661 0.52023 26.5487
356 3DKP ADP 0.0002951 0.49775 26.5487
357 3ZIA ADP 0.0001828 0.49066 26.5487
358 1WF3 GNP 0.000000003823 0.63991 27.4286
359 3DZD ADP 0.0006507 0.46513 27.4336
360 1HTW ADP 0.00008464 0.40773 27.8481
361 3AQ4 GDP 0.000000000619 0.76696 28
362 3DOE GTP 0.0000000003057 0.70834 28
363 1JJV ATP 0.00006754 0.54825 28
364 3DEF GDP 0.0000001852 0.62929 28.3186
365 2PL3 ADP 0.0003488 0.50033 30.0885
366 5DI3 GNP 0.00000000006379 0.74639 30.2857
367 5KUT GDP 0.0000000003361 0.56714 30.2857
368 2X77 GDP 0.0000000005415 0.76977 31.4286
369 2Z5F A3P 0.009965 0.40025 31.8584
370 1YRB GDP 0.000000000159 0.77125 32
371 1YZG GDP 0.000000001109 0.75469 32.5714
372 3CX8 GSP 0.00000000008 0.6803 32.7434
373 1ZCB GDP 0.00000002706 0.59944 32.7434
374 3AB3 GDP 0.00000002469 0.57098 32.7434
375 1KSH GDP 0.00000000002709 0.66868 33.1429
376 1M2O GNP 0.000000002269 0.64061 33.1429
377 1S9D GDP 0.000000001478 0.74864 33.5366
378 1RE0 GDP 0.000000001435 0.53023 33.5366
379 2A5F GTP 0.0000000003843 0.69556 33.7143
380 2ZEJ GDP 0.0000004799 0.55701 33.7143
381 1J2J GTP 0.0000000005917 0.69635 33.7349
382 2J59 GTP 0.000000001063 0.68572 33.7349
383 1O3Y GTP 0.000000001258 0.68267 33.7349
384 1NRJ GTP 0.000000004694 0.67532 34.4037
385 2QTV GNP 0.000000002741 0.62959 34.7305
386 4KAX GTP 0.000000000231 0.6501 35.503
387 1X6V ADP 0.002406 0.40029 36.2832
388 2W83 GTP 0.0000000007272 0.69261 36.3636
389 3N5C GDP 0.000000002715 0.74765 36.4198
390 5M04 GDP 0.000000002524 0.76183 37.1429
391 1MKY GDP 0.00000000001405 0.86108 37.7143
392 1ZJ6 G3D 0.000000001087 0.75511 38.2857
393 1K6M AGS 0.002343 0.42069 38.2857
394 1R4A GNP 0.00000000001947 0.74866 39.3939
395 5EE5 GTP 0.00000000001897 0.76883 39.7661
396 4YLG GDP 0.0000000009693 0.72447 39.8844
397 1ZD9 GDP 0.00000000002689 0.78361 40.5714
398 1F6B GDP 0.00000003552 0.68174 42.2857
399 3REF GDP 0.000000002029 0.68238 42.8571
400 1A4R GNH 0.000000001237 0.71967 45.1429
401 1A4R GDP 0.000000001176 0.71082 45.1429
402 2NGR GDP 0.000000000003516 0.87575 45.7143
403 2WMO GTP 0.00000000003652 0.8133 45.7143
404 1GRN GDP 0.00000000004534 0.78472 45.7143
405 4DID GDP 0.0000000003319 0.78007 45.7143
406 4YC7 GNP 0.000000000001312 0.73096 45.7143
407 2NGR AF3 0.00000002533 0.72301 45.7143
408 4ITR GDP 0.000000007434 0.6753 45.7143
409 1GRN AF3 0.0000003676 0.66237 45.7143
410 1NF3 GNP 0.000000000005432 0.7617 46.2857
411 3GJ7 GDP 0.00000000006528 0.82798 46.8571
412 3E5H GNP 0.0000000000001265 0.8274 46.8571
413 3GJ4 GDP 0.00000000006896 0.8268 46.8571
414 3GJ8 GDP 0.0000000001812 0.7928 46.8571
415 3GJ5 GDP 0.0000000001904 0.79176 46.8571
416 3GJ0 GDP 0.00000000006985 0.82653 47.4286
417 3GJ3 GDP 0.0000000000853 0.82222 47.4286
418 5DIF GNP 0.0000000000001864 0.81023 47.4286
419 5UWJ GNP 0.0000000000001993 0.80908 47.4286
420 5UWI GNP 0.0000000000002277 0.8068 47.4286
421 5UWW GNP 0.0000000000002313 0.80653 47.4286
422 5UWR GNP 0.0000000000002348 0.80627 47.4286
423 5UWQ GNP 0.0000000000002438 0.80562 47.4286
424 5UWU GNP 0.0000000000002524 0.80503 47.4286
425 5UWO GNP 0.0000000000002599 0.80453 47.4286
426 5UWT GNP 0.0000000000002653 0.80417 47.4286
427 5BXQ GDP 0.000000000106 0.80409 47.4286
428 5DHF GNP 0.0000000000003273 0.80057 47.4286
429 5UWH GNP 0.0000000000003362 0.80012 47.4286
430 1IBR GNP 0.0000000000004277 0.79599 47.4286
431 5UWP GNP 0.0000000000002625 0.78758 47.4286
432 4HAT GNP 0.0000000000002649 0.78737 47.4286
433 5DI9 GNP 0.0000000000003617 0.78235 47.4286
434 5UWS GNP 0.0000000000004979 0.77715 47.4286
435 4U5X GNP 0.0000000001125 0.75604 47.4286
436 1WA5 GTP 0.0000000000007246 0.72741 47.4286
437 3GJX GTP 0.0000000000006989 0.78756 48
438 2J0V GDP 0.00000000008939 0.58562 48
439 2W2X GSP 0.00000000000597 0.80116 48.5714
440 1CXZ GSP 0.000000000005588 0.79145 48.5714
441 1TX4 ALF GDP 0.000000000005406 0.78155 48.5714
442 5HPY GDP 0.0000000001296 0.76406 48.5714
443 5JCP GDP ALF 0.0000000001466 0.76164 48.5714
444 5IRC GDP 0.0000000004998 0.75951 48.5714
445 4XSH GSP 0.00000000009838 0.75863 48.5714
446 1OW3 GDP 0.0000000001071 0.62645 48.5714
447 3RAB GNP 0.000000000000008549 0.84961 49.1124
448 3SBD GNP 0.00000000000002631 0.85484 49.1429
449 1KMQ GNP 0.000000000002584 0.79494 49.1429
450 4XOI GTP 0.000000000001692 0.79215 49.1429
451 2GCO GNP 0.00000000004469 0.78501 49.1429
452 3LXR GDP 0.0000000004766 0.76049 49.1429
453 2FJU GSP 0.000000000001687 0.71418 49.1429
454 2GCN GDP 0.000000001965 0.61598 49.1429
455 4D0N GDP 0.0000000000907 0.56847 49.1429
Pocket No.: 2; Query (leader) PDB : 1ZC3; Ligand: GNP; Similar sites found: 22
This union binding pocket(no: 2) in the query (biounit: 1zc3.bio2) has 26 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 3R7F CP 0.0237 0.41103 4.42478
2 2Y65 ADP 0.00000497 0.40134 4.42478
3 2O66 FLC 0.03158 0.40333 4.44444
4 4QAG F95 0.0222 0.40759 6.01504
5 1V6A TRE 0.02558 0.40865 6.19469
6 2P3V SRT 0.0301 0.40599 6.19469
7 2KIN ADP 0.000001671 0.40043 6.19469
8 1VBO MAN 0.01035 0.42649 7.07965
9 1VBO MAN MAN MAN 0.02981 0.40574 7.07965
10 4WEI GLC GAL 0.02227 0.41762 7.42857
11 4FCW ADP 0.0003058 0.40027 7.42857
12 2Z48 NGA 0.004612 0.45104 8
13 5SXS NIZ 0.01426 0.40551 8.57143
14 4MDB RLT 0.0197 0.42027 9.71429
15 5UIJ TYD 0.009682 0.40489 9.71429
16 5TCI MLI 0.03584 0.40014 9.71429
17 1BG2 ADP 0.000001273 0.4021 9.73451
18 1R0X ATP 0.00006819 0.4098 10.8571
19 1NT4 G1P 0.02144 0.41326 12.3894
20 1U2Z SAH 0.003896 0.40087 15.0442
21 3EWA ANP 0.00006809 0.40431 18.5841
22 4LZB URA 0.02454 0.40454 18.8571
Feedback