-->
Receptor
PDB id Resolution Class Description Source Keywords
1ZTH 1.89 Å EC: 2.-.-.- CRYSTAL STRUCTURE OF A.FULGIDUS RIO1 SERINE PROTEIN KINASE B ADP AND MANGANESE ION ARCHAEOGLOBUS FULGIDUS PROTEIN KINASE RIBOSOME BIOGENESIS RRNA ADP MANGANESE TRANSFERASE
Ref.: STRUCTURE AND ACTIVITY OF THE ATYPICAL SERINE KINAS FEBS J. V. 272 3698 2005
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ADP A:901;
B:903;
C:905;
D:907;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
submit data
427.201 C10 H15 N5 O10 P2 c1nc(...
MN A:902;
B:904;
C:906;
D:908;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
none;
none;
none;
none;
submit data
54.938 Mn [Mn+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1ZTH 1.89 Å EC: 2.-.-.- CRYSTAL STRUCTURE OF A.FULGIDUS RIO1 SERINE PROTEIN KINASE B ADP AND MANGANESE ION ARCHAEOGLOBUS FULGIDUS PROTEIN KINASE RIBOSOME BIOGENESIS RRNA ADP MANGANESE TRANSFERASE
Ref.: STRUCTURE AND ACTIVITY OF THE ATYPICAL SERINE KINAS FEBS J. V. 272 3698 2005
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 269 families.
1 1ZTH - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 237 families.
1 1ZTH - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 187 families.
1 1ZTH - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ADP; Similar ligands found: 452
No: Ligand ECFP6 Tc MDL keys Tc
1 ADP 1 1
2 HEJ 0.9 1
3 ATP 0.9 1
4 A2D 0.895522 0.971831
5 5FA 0.887324 1
6 AQP 0.887324 1
7 AP5 0.884058 0.971831
8 B4P 0.884058 0.971831
9 BA3 0.869565 0.971831
10 AN2 0.84507 0.985915
11 AT4 0.84507 0.958904
12 M33 0.833333 0.958333
13 ACQ 0.826667 0.972222
14 A 0.823529 0.971429
15 AMP 0.823529 0.971429
16 ACP 0.821918 0.972222
17 6YZ 0.818182 0.972222
18 APR 0.810811 0.971831
19 AR6 0.810811 0.971831
20 ANP 0.802632 0.972222
21 SAP 0.8 0.945946
22 AGS 0.8 0.945946
23 AD9 0.8 0.972222
24 ADX 0.783784 0.873418
25 CA0 0.783784 0.945205
26 TAT 0.779221 0.958904
27 T99 0.779221 0.958904
28 50T 0.773333 0.958333
29 ABM 0.763889 0.917808
30 APC 0.763158 0.958904
31 PRX 0.763158 0.893333
32 ATF 0.759494 0.958904
33 A22 0.753086 0.985915
34 AP2 0.743243 0.958904
35 A12 0.743243 0.958904
36 SRA 0.736111 0.918919
37 ADQ 0.73494 0.945205
38 25L 0.732558 0.985915
39 5AL 0.725 0.931507
40 2A5 0.717949 0.918919
41 A1R 0.714286 0.907895
42 AU1 0.714286 0.972222
43 A3R 0.714286 0.907895
44 ATR 0.708861 0.971429
45 ADP PO3 0.708861 0.943662
46 PAP 0.708861 0.985714
47 SRP 0.707317 0.906667
48 7D3 0.706667 0.905405
49 25A 0.702381 0.971831
50 9X8 0.697674 0.92
51 OAD 0.697674 0.945205
52 RBY 0.6875 0.932432
53 ADV 0.6875 0.932432
54 00A 0.686047 0.883117
55 OOB 0.682353 0.931507
56 5SV 0.682353 0.848101
57 8QN 0.682353 0.931507
58 3OD 0.681818 0.945205
59 BIS 0.681818 0.933333
60 ALF ADP 0.674699 0.87013
61 ADP ALF 0.674699 0.87013
62 AMO 0.674419 0.932432
63 4AD 0.674419 0.92
64 PAJ 0.674419 0.884615
65 GAP 0.670732 0.893333
66 MAP 0.670588 0.945946
67 AHX 0.666667 0.896104
68 VO4 ADP 0.666667 0.931507
69 DLL 0.666667 0.931507
70 ADP VO4 0.666667 0.931507
71 PTJ 0.662921 0.896104
72 3UK 0.659091 0.918919
73 SON 0.658228 0.932432
74 LMS 0.653333 0.82716
75 LAD 0.651685 0.860759
76 WAQ 0.651685 0.883117
77 B5V 0.651685 0.906667
78 PR8 0.651685 0.85
79 ITT 0.65 0.943662
80 7D4 0.65 0.905405
81 G5P 0.648936 0.921053
82 XYA 0.647059 0.84507
83 ADN 0.647059 0.84507
84 RAB 0.647059 0.84507
85 1ZZ 0.644444 0.839506
86 ME8 0.644444 0.839506
87 FYA 0.644444 0.905405
88 NB8 0.644444 0.896104
89 TXA 0.644444 0.932432
90 6AD 0.642857 0.909091
91 ADP BMA 0.640449 0.918919
92 G3A 0.638298 0.921053
93 DAL AMP 0.632184 0.905405
94 AFH 0.631579 0.884615
95 9SN 0.630435 0.871795
96 9ZA 0.625 0.907895
97 DQV 0.625 0.958333
98 9ZD 0.625 0.907895
99 GTA 0.625 0.886076
100 YAP 0.623656 0.894737
101 B5M 0.623656 0.894737
102 FA5 0.623656 0.906667
103 B5Y 0.623656 0.894737
104 UP5 0.622449 0.92
105 HFD 0.619048 0.945946
106 XAH 0.617021 0.839506
107 AV2 0.616279 0.917808
108 AOC 0.615385 0.821918
109 48N 0.612245 0.896104
110 4UV 0.610526 0.894737
111 6V0 0.606061 0.896104
112 NAI 0.606061 0.907895
113 DND 0.606061 0.932432
114 NAX 0.606061 0.873418
115 NXX 0.606061 0.932432
116 TXD 0.606061 0.907895
117 5N5 0.605634 0.819444
118 5AS 0.604938 0.77907
119 A4P 0.60396 0.843373
120 DAT 0.60241 0.905405
121 A2R 0.602273 0.985915
122 TXE 0.6 0.907895
123 OMR 0.6 0.851852
124 4UU 0.597938 0.894737
125 GA7 0.597938 0.906667
126 A A 0.597826 0.944444
127 A4D 0.597222 0.819444
128 5CD 0.597222 0.805556
129 AP0 0.594059 0.896104
130 4TC 0.594059 0.896104
131 A3P 0.592593 0.971429
132 T5A 0.592233 0.841463
133 139 0.592233 0.873418
134 7D5 0.592105 0.878378
135 ATP A A A 0.589474 0.930556
136 LAQ 0.585859 0.839506
137 MYR AMP 0.585106 0.817073
138 F2R 0.580952 0.864198
139 YLP 0.58 0.819277
140 UPA 0.578431 0.907895
141 7DD 0.578313 0.985714
142 3AM 0.576923 0.929577
143 ADJ 0.576923 0.851852
144 COD 0.575472 0.811765
145 NAD 0.575472 0.931507
146 3AT 0.574713 0.971831
147 JB6 0.574468 0.883117
148 4UW 0.574257 0.860759
149 EP4 0.573333 0.753247
150 A2P 0.573171 0.957143
151 CNA 0.571429 0.932432
152 TYM 0.568627 0.906667
153 PPS 0.568182 0.873418
154 DTA 0.565789 0.786667
155 M2T 0.565789 0.734177
156 AR6 AR6 0.565657 0.917808
157 A3D 0.564815 0.918919
158 80F 0.564815 0.841463
159 3DH 0.564103 0.773333
160 G5A 0.563218 0.77907
161 YLB 0.563107 0.819277
162 YLC 0.563107 0.839506
163 AMP DBH 0.561224 0.893333
164 TYR AMP 0.561224 0.87013
165 MTA 0.558442 0.773333
166 DTP 0.556818 0.905405
167 AHZ 0.554455 0.817073
168 NA7 0.553191 0.958904
169 IOT 0.552381 0.831325
170 ZAS 0.55 0.766234
171 7MD 0.55 0.8625
172 ARG AMP 0.55 0.829268
173 IMO 0.548781 0.929577
174 YLA 0.54717 0.819277
175 NAE 0.544643 0.894737
176 TAD 0.544554 0.884615
177 A5A 0.544444 0.807229
178 2AM 0.544304 0.943662
179 TSB 0.543478 0.819277
180 6RE 0.54321 0.759494
181 AYB 0.542056 0.809524
182 NAQ 0.539823 0.871795
183 V3L 0.539326 0.971831
184 SSA 0.538462 0.8
185 AF3 ADP 3PG 0.538462 0.8375
186 ZID 0.535088 0.918919
187 LPA AMP 0.533981 0.817073
188 52H 0.532609 0.77907
189 VMS 0.532609 0.788235
190 54H 0.532609 0.788235
191 BTX 0.53211 0.841463
192 A3N 0.53012 0.786667
193 J7C 0.53012 0.769231
194 5X8 0.528736 0.763158
195 BT5 0.527273 0.831325
196 8X1 0.526882 0.752809
197 5CA 0.526882 0.8
198 53H 0.526882 0.77907
199 ARU 0.526316 0.860759
200 EAD 0.525862 0.873418
201 RGT 0.525253 0.958904
202 OVE 0.52439 0.905405
203 S4M 0.52381 0.666667
204 7DT 0.522727 0.985714
205 GDP 0.522222 0.92
206 DDS 0.522222 0.878378
207 AVV 0.521277 0.896104
208 NDE 0.521008 0.932432
209 7MC 0.518868 0.841463
210 DSH 0.518072 0.725
211 MAO 0.517647 0.759036
212 NSS 0.515789 0.8
213 DSZ 0.515789 0.8
214 LSS 0.515789 0.761364
215 P5A 0.515464 0.744444
216 DZD 0.513514 0.884615
217 NVA LMS 0.510417 0.752809
218 9K8 0.510204 0.714286
219 12D 0.509615 0.785714
220 M24 0.508772 0.85
221 YLY 0.508772 0.809524
222 P1H 0.508333 0.851852
223 5AD 0.506849 0.746479
224 GJV 0.505882 0.75
225 LEU LMS 0.505155 0.752809
226 AMP NAD 0.504505 0.905405
227 4TA 0.504505 0.807229
228 G A A A 0.504505 0.871795
229 NAJ PZO 0.504425 0.848101
230 GSU 0.5 0.77907
231 128 0.5 0.776471
232 KAA 0.5 0.752809
233 71V 0.5 0.907895
234 A3G 0.5 0.8
235 NDC 0.5 0.871795
236 7D7 0.5 0.743243
237 N0B 0.495726 0.819277
238 NJP 0.495495 0.945946
239 ODP 0.495495 0.909091
240 2SA 0.494624 0.932432
241 6C6 0.494505 0.881579
242 SFG 0.494382 0.75
243 0WD 0.491071 0.921053
244 YSA 0.490196 0.77907
245 PO4 PO4 A A A A PO4 0.489796 0.902778
246 SAM 0.48913 0.690476
247 6IA 0.48913 0.8375
248 A7D 0.488636 0.776316
249 6FA 0.488 0.841463
250 FB0 0.487805 0.804598
251 NAJ PYZ 0.487179 0.807229
252 A5D 0.483516 0.786667
253 IDP 0.483516 0.918919
254 SA8 0.483516 0.707317
255 PGS 0.483146 0.883117
256 MHZ 0.483146 0.697674
257 DA 0.482353 0.878378
258 D5M 0.482353 0.878378
259 NEC 0.482353 0.746667
260 NIA 0.481928 0.822785
261 Y3J 0.480519 0.726027
262 8PZ 0.480392 0.8
263 FAD 0.480315 0.851852
264 FAS 0.480315 0.851852
265 FDA 0.48 0.833333
266 N6P 0.479592 0.915493
267 GGZ 0.479167 0.825
268 U A 0.478261 0.907895
269 SAH 0.478261 0.74359
270 SAI 0.478261 0.734177
271 A G 0.477876 0.883117
272 NPW 0.477477 0.886076
273 NDP 0.477477 0.921053
274 AAM 0.476744 0.971429
275 C2R 0.47561 0.90411
276 AMZ 0.47561 0.916667
277 A A A 0.474747 0.905405
278 GTP 0.473684 0.92
279 U A G G 0.473684 0.883117
280 SMM 0.473684 0.686047
281 NZQ 0.473214 0.909091
282 TXP 0.473214 0.921053
283 A3S 0.47191 0.810811
284 SFD 0.46875 0.734043
285 AIR 0.468354 0.901408
286 AAT 0.468085 0.707317
287 EEM 0.468085 0.690476
288 J7V 0.466667 0.833333
289 Z5A 0.466667 0.77907
290 7C5 0.466667 0.818182
291 62F 0.465649 0.8625
292 HDV 0.463158 0.893333
293 FAY 0.462121 0.8625
294 A3T 0.461538 0.821918
295 ETB 0.461538 0.833333
296 DCA 0.461538 0.823529
297 A6D 0.46 0.722892
298 A U 0.459459 0.87013
299 GEK 0.459184 0.7375
300 6K6 0.459184 0.930556
301 RFL 0.458647 0.821429
302 NAP 0.458333 0.945205
303 S7M 0.458333 0.690476
304 4YB 0.457944 0.761364
305 WSA 0.454545 0.788235
306 TAP 0.454545 0.907895
307 FNK 0.454545 0.804598
308 COA 0.453782 0.823529
309 0T1 0.453782 0.823529
310 101 0.453488 0.878378
311 XNP 0.452174 0.873418
312 NA0 0.45082 0.932432
313 7RP 0.448276 0.928571
314 GP3 0.446809 0.921053
315 TM1 0.446602 0.77381
316 APU 0.446429 0.894737
317 PUA 0.445378 0.884615
318 V1N 0.443396 0.917808
319 7RA 0.443182 0.957747
320 COS 0.442623 0.804598
321 AMX 0.442623 0.833333
322 30N 0.442623 0.752688
323 CAO 0.442623 0.795455
324 QQY 0.44186 0.815789
325 ACK 0.44186 0.861111
326 649 0.441441 0.744444
327 0UM 0.44 0.698795
328 NHD 0.439655 0.905405
329 CMX 0.439024 0.823529
330 SCO 0.439024 0.823529
331 GCP 0.438776 0.896104
332 8BR 0.438202 0.906667
333 GNH 0.4375 0.907895
334 8Q2 0.4375 0.772727
335 3AD 0.4375 0.805556
336 NVA 2AD 0.43617 0.759494
337 62X 0.435644 0.666667
338 FCX 0.435484 0.795455
339 ACO 0.435484 0.795455
340 FAM 0.435484 0.804598
341 9JJ 0.434783 0.8625
342 GNP 0.434343 0.896104
343 9GM 0.434343 0.896104
344 NMX 0.433071 0.76087
345 MGP 0.43299 0.884615
346 26A 0.432099 0.763158
347 HAX 0.432 0.804598
348 K15 0.431373 0.682353
349 DG1 0.430894 0.921053
350 1DG 0.430894 0.921053
351 QQX 0.430233 0.805195
352 2VA 0.430108 0.8
353 S8M 0.43 0.759494
354 2MC 0.429688 0.769231
355 6G0 0.428571 0.884615
356 P5F 0.428571 0.823529
357 FYN 0.428571 0.823529
358 3KK 0.428571 0.804598
359 A C A C 0.428571 0.848101
360 7L1 0.427419 0.795455
361 FAI 0.426966 0.916667
362 RMB 0.426966 0.873239
363 AS 0.426966 0.833333
364 1RB 0.425287 0.885714
365 CA6 0.425197 0.729167
366 SOP 0.425197 0.804598
367 OXK 0.425197 0.804598
368 MCD 0.425197 0.804598
369 COK 0.425197 0.804598
370 G1R 0.424242 0.907895
371 SXZ 0.423077 0.710843
372 CC5 0.423077 0.816901
373 F2N 0.422535 0.813953
374 EO7 0.422222 0.788235
375 ANZ 0.422018 0.8
376 1VU 0.421875 0.795455
377 CMC 0.421875 0.804598
378 CO6 0.421875 0.804598
379 ZDA 0.421053 0.864865
380 GKE 0.420561 0.884615
381 GDC 0.420561 0.884615
382 GDD 0.420561 0.884615
383 NFD 0.420168 0.883117
384 GSP 0.42 0.873418
385 D3Y 0.42 0.789474
386 MC4 0.419847 0.76087
387 3D1 0.419753 0.773333
388 3L1 0.419753 0.773333
389 FA9 0.41958 0.864198
390 5GP 0.419355 0.906667
391 G 0.419355 0.906667
392 KB1 0.419048 0.698795
393 CAJ 0.418605 0.804598
394 SCD 0.418605 0.823529
395 CMP 0.417582 0.901408
396 2BA 0.417582 0.915493
397 SO8 0.416667 0.789474
398 VRT 0.416667 0.769231
399 N01 0.416667 0.905405
400 IVC 0.415385 0.813953
401 1HE 0.415385 0.786517
402 A1S 0.415385 0.804598
403 BCO 0.415385 0.804598
404 3HC 0.415385 0.813953
405 MLC 0.415385 0.804598
406 NMN AMP PO4 0.415254 0.87013
407 2FA 0.414634 0.813333
408 MGO 0.414141 0.860759
409 3NZ 0.413462 0.782051
410 COO 0.412214 0.804598
411 MCA 0.412214 0.795455
412 YE1 0.412214 0.813953
413 CAA 0.412214 0.813953
414 GAV 0.411765 0.884615
415 PRT 0.411215 0.931507
416 JLN 0.411111 0.890411
417 P2P 0.411111 0.902778
418 ZZB 0.410256 0.77381
419 SP1 0.409091 0.842105
420 RP1 0.409091 0.842105
421 2CP 0.409091 0.795455
422 SCA 0.409091 0.804598
423 103 0.409091 0.837838
424 PAX 0.408 0.829268
425 FAD NBT 0.407143 0.75
426 COW 0.406015 0.795455
427 3CP 0.406015 0.804598
428 IRC 0.406015 0.813953
429 BYC 0.406015 0.804598
430 CA8 0.406015 0.729167
431 1GZ 0.406015 0.795455
432 COF 0.406015 0.786517
433 HGG 0.406015 0.804598
434 2KQ 0.406015 0.786517
435 G2P 0.405941 0.884615
436 SLU 0.404959 0.770115
437 U A C C 0.404959 0.858974
438 RBZ 0.404494 0.849315
439 1CZ 0.404412 0.795455
440 FAQ 0.402985 0.804598
441 BCA 0.402985 0.795455
442 4CA 0.402985 0.795455
443 MTP 0.402439 0.730769
444 8OD 0.402062 0.945205
445 CO7 0.401515 0.804598
446 GRA 0.4 0.804598
447 G2R 0.4 0.884615
448 ENQ 0.4 0.916667
449 CNV FAD 0.4 0.8
450 GMV 0.4 0.896104
451 HXC 0.4 0.786517
452 HF7 0.4 0.893333
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1ZTH; Ligand: ADP; Similar sites found with APoc: 433
This union binding pocket(no: 1) in the query (biounit: 1zth.bio4) has 16 residues
No: Leader PDB Ligand Sequence Similarity
1 4U98 ACP 1.16279
2 2QX0 PH2 1.25786
3 5QIN J2V 1.55039
4 5ZCT ANP 1.55039
5 3KAL ADP 1.55039
6 5LI1 ANP 1.93798
7 3MVH WFE 1.93798
8 2PUL ACP 1.93798
9 3SLS ANP 1.93798
10 3E8N VRA 1.93798
11 3E8N ATP 1.93798
12 4OCJ NDG 1.93798
13 3VPC ADP 1.93798
14 3CH6 NAP 1.93798
15 3CH6 311 1.93798
16 4C5N ACP 1.93798
17 4C5N PXL 1.93798
18 5MN0 A8S 1.93798
19 2FXD DR7 2.0202
20 1CEB AMH 2.27273
21 2JDR L20 2.32558
22 2JDR GLY ARG PRO ARG THR THR SER PHE ALA GLU 2.32558
23 3TXO 07U 2.32558
24 6C0T EE4 2.32558
25 5IH9 6BF 2.32558
26 5JGA 6KC 2.32558
27 5EW9 5VC 2.32558
28 5T8O 76Z 2.32558
29 4Y0X ADP 2.32558
30 4G17 0VN 2.32558
31 4AT3 LTI 2.32558
32 5ODT ADP 2.32558
33 1K3A ACP 2.32558
34 4YMJ 4EJ 2.32558
35 5LXM ADP 2.32558
36 3E5A VX6 2.32558
37 5AE9 OKO 2.32558
38 3NW7 LGV 2.32558
39 2PZI AXX 2.32558
40 5UIU 8CG 2.32558
41 6EZ6 C5Z 2.32558
42 5WBF LAC 2.32558
43 4H4D 10E 2.32558
44 6F3G CJN 2.37288
45 2GU8 796 2.71318
46 4WB6 ATP 2.71318
47 5X8I SQZ 2.71318
48 4WB7 ATP 2.71318
49 4OTH DRN 2.71318
50 1RE8 BD2 2.71318
51 5JFS 6K0 2.71318
52 3LXK MI1 2.71318
53 6E2O S0L 2.71318
54 5DEY 59T 2.71318
55 6FYV 3NG 2.71318
56 2F57 23D 2.71318
57 6G33 5ID 2.71318
58 4CYI ATP 2.71318
59 1O9U ADZ 2.71318
60 3X01 AMP 2.71318
61 5C1P DAL DAL 2.71318
62 5C1P ADP 2.71318
63 4JTA NAP 2.71318
64 5EXK 5AD 2.71318
65 4NW6 2NS 3.10078
66 5WNL STU 3.10078
67 3PLS ANP 3.10078
68 6C7Y ADP 3.10078
69 3V8S 0HD 3.10078
70 6CQF F97 3.10078
71 2R5T ANP 3.10078
72 2F2U M77 3.10078
73 5WO4 B7V 3.10078
74 5FBN 5WF 3.10078
75 4Y93 746 3.10078
76 3FHR P4O 3.10078
77 2IF8 ADP 3.10078
78 1IA9 ANP 3.10078
79 6GIN IR2 3.10078
80 3WVR AMP 3.10078
81 3H9R TAK 3.10078
82 3TII ANP 3.10078
83 2YW2 ATP 3.10078
84 2QF7 AGS 3.10078
85 1A99 PUT 3.10078
86 3FYS PLM 3.10078
87 4L77 CNL 3.10078
88 5YW5 ADE 3.35196
89 4N70 2HX 3.48837
90 6FYL 3NG 3.48837
91 5LPZ ADP 3.48837
92 2JLD AG1 3.48837
93 3RWP ABQ 3.48837
94 3F7Z 34O 3.48837
95 4L3L 5FI 3.48837
96 5BVE 4VG 3.48837
97 5I35 ANP 3.48837
98 3ZRM ZRM 3.48837
99 2V7O DRN 3.48837
100 4OH4 ANP 3.48837
101 4NM5 ADP 3.48837
102 3TKI S25 3.48837
103 5MW8 ATP 3.48837
104 5HES 032 3.48837
105 4QTB 38Z 3.48837
106 2XK9 XK9 3.48837
107 2VN9 GVD 3.48837
108 5LPB ADP 3.48837
109 5LVP ATP 3.48837
110 4E1Z 0MX 3.48837
111 2HY0 306 3.48837
112 2VZ6 FEF 3.48837
113 6BFN DL1 3.48837
114 6GQM F8H 3.48837
115 6ES0 BW8 3.48837
116 5DBX ANP 3.48837
117 3CY2 MB9 3.48837
118 2V58 LZJ 3.48837
119 5VLQ ANP 3.48837
120 6F9G PUT 3.48837
121 2FLI DX5 3.63636
122 4UXL 5P8 3.72671
123 3G5D 1N1 3.87597
124 2YAK OSV 3.87597
125 2B9H ADP 3.87597
126 2B9F ADP 3.87597
127 2B9J ADP 3.87597
128 2B9I ADP 3.87597
129 4H3Q ANP 3.87597
130 1Y57 MPZ 3.87597
131 2H8H H8H 3.87597
132 1PHK ATP 3.87597
133 5ZTN CUR 3.87597
134 4CLI 5P8 3.87597
135 2X2M X2M 3.87597
136 4H3P ANP 3.87597
137 3ALN ANP 3.87597
138 4WNK 453 3.87597
139 3DAK ANP 3.87597
140 4IX4 ADP 3.87597
141 3HZT J60 3.87597
142 3PDT ADP 3.87597
143 4ZS4 ATP 3.87597
144 2IO8 ADP 3.87597
145 4UWH JXM 3.87597
146 4DFU QUE 3.87597
147 1GPM AMP 3.87597
148 2QK4 ATP 3.87597
149 3PH4 AOS 4.14201
150 4E93 GUI 4.26357
151 6G34 5ID 4.26357
152 4IJP 1EH 4.26357
153 1Q8Y ADP 4.26357
154 1ZY5 ANP 4.26357
155 4KS7 X4Z 4.26357
156 5DRB 5FJ 4.26357
157 1Q8Y ADE 4.26357
158 5C03 AGS 4.26357
159 1W2D 4IP 4.26357
160 1W2D ADP 4.26357
161 4OUC 5ID 4.26357
162 1TZD ADP 4.26357
163 2VPQ ANP 4.26357
164 1I7L ATP 4.26357
165 2Q7D ANP 4.26357
166 3ETH ATP 4.26357
167 4WOV 3SM 4.26357
168 2QLU ADE 4.26357
169 3WO0 ALA 4.26357
170 3WO0 ADP 4.26357
171 5HVJ ANP 4.26357
172 5OLK DTP 4.26357
173 5DXT 5H5 4.26357
174 3ORQ ADP 4.26357
175 4WTV ATP 4.26357
176 5L8L ADP 4.2735
177 5EQY 5RA 4.65116
178 6A1G 9OL 4.65116
179 5W4W 9WG 4.65116
180 4ASE AV9 4.65116
181 3M2W L8I 4.65116
182 4KBA 1QM 4.65116
183 4AG8 AXI 4.65116
184 2RIO ADP 4.65116
185 5DH3 5BS 4.65116
186 4BHN BH9 4.65116
187 1OPK P16 4.65116
188 5OKT 9XK 4.65116
189 3DNT ATP 4.65116
190 5CEO 50D 4.65116
191 1KJ8 GAR 4.65116
192 1KJ8 ATP 4.65116
193 3TPV ADE 4.65116
194 3KCC CMP 4.65116
195 2VK2 GZL 4.65116
196 2OQ2 A3P 4.65116
197 3HEE R5P 4.69799
198 3OJI PYV 4.7619
199 4EKQ NPO 4.81283
200 3IDB ANP 4.96894
201 1VJY 460 5.03876
202 4TWP AXI 5.03876
203 6BXI ANP 5.03876
204 4K33 ACP 5.03876
205 5EOB 5QQ 5.03876
206 2WQN ADP 5.03876
207 4I94 ANP 5.03876
208 6GWR FEW 5.03876
209 4AUA 4AU 5.03876
210 3VOT ADP 5.03876
211 5IM3 DTP 5.03876
212 2A19 ANP 5.14286
213 1WAP TRP 5.33333
214 4XV1 904 5.42636
215 2HK5 1BM 5.42636
216 4YZN 4K5 5.42636
217 4CQE CQE 5.42636
218 2PVF ACP 5.42636
219 5LI9 ACP 5.42636
220 3RI1 3RH 5.42636
221 3VRY B43 5.42636
222 3VHE 42Q 5.42636
223 1BYG STU 5.42636
224 5UR1 YY9 5.42636
225 4P5Z Q7M 5.42636
226 3GC8 B45 5.42636
227 2Y6O 1N1 5.42636
228 3DLS ADP 5.42636
229 4LOO SB4 5.42636
230 5MJA 7O3 5.42636
231 4DC2 ADE 5.42636
232 2R7K ACP 5.42636
233 2R7K AMZ 5.42636
234 1EHI ADP 5.42636
235 4N9I PCG 5.71429
236 2QCS ANP 5.81395
237 5U6C 7YS 5.81395
238 4FG8 ATP 5.81395
239 5EFQ ADP 5.81395
240 5GZ9 ANP 5.81395
241 3UIM ANP 5.81395
242 3GGF GVD 5.81395
243 2XVD AS6 5.81395
244 2AQX ATP 5.81395
245 6C1S EFV 5.81395
246 3V4S ATP 5.81395
247 3V4S ADP 5.81395
248 5OES ADP 5.81395
249 3IGO ANP 6.20155
250 4UAL 3FV 6.20155
251 5NKB 8ZT 6.20155
252 4BTK DTQ 6.20155
253 4EWH T77 6.20155
254 4OCV ANP 6.20155
255 4A4X JUP 6.20155
256 4NFN 2KC 6.20155
257 5YK1 ANP 6.20155
258 1GSA ADP 6.20155
259 5EKO N17 6.20155
260 3C1X CKK 6.20155
261 3AQV TAK 6.20155
262 6AC9 ANP 6.20155
263 6BSX E7S 6.20155
264 5LXT ACP 6.29371
265 4XYM A12 6.52174
266 4XZ3 ACP 6.52174
267 2PYW ADP 6.58915
268 1XJD STU 6.58915
269 4NST ADP 6.58915
270 5TA6 79D 6.58915
271 5USZ SKE 6.58915
272 4RFM 3P6 6.58915
273 3FC2 IBI 6.58915
274 4CSV STI 6.58915
275 4I6H 1C8 6.58915
276 3KRL KRL 6.58915
277 3AKK ADP 6.58915
278 1Q19 SSC 6.58915
279 4GJ3 0XP 6.97674
280 3LXN MI1 6.97674
281 4EUU BX7 6.97674
282 5H2U 1N1 6.97674
283 6CZ3 FLJ 6.97674
284 3VPD ANP 6.97674
285 2VQD AP2 6.97674
286 5DZT AMP 6.97674
287 2WEL K88 7.33333
288 5M06 ADP 7.36434
289 3BZ3 YAM 7.36434
290 3SXS PP2 7.36434
291 1AUX AGS 7.36434
292 4PU5 ANP 7.36434
293 1IOW PHY 7.36434
294 1IOW ADP 7.36434
295 5K2M ADP 7.54717
296 5XVG 8FX 7.75194
297 4XH0 ADP 7.75194
298 4O4F IHP 8.06452
299 4O4F ATP 8.06452
300 3PVW QRX 8.10811
301 5Y86 HRM 8.13953
302 4WNP 3RJ 8.13953
303 4O1P ANP 8.13953
304 6FL8 TIY 8.13953
305 6FL8 ADP 8.13953
306 3UDZ ADP 8.13953
307 1U59 STU 8.13953
308 5C4L SIS 8.13953
309 5C4L 4XR 8.13953
310 2OFV 242 8.13953
311 4ZGP ADP 8.13953
312 5FI4 5XV 8.13953
313 2GQR ADP 8.43882
314 2GQS ADP 8.43882
315 5EYK 5U5 8.47458
316 3W0O HY0 8.52713
317 3W0O ADP 8.52713
318 5TDF ADP 8.52713
319 5UPK ANP 8.64865
320 4YZC STU 8.91473
321 4M69 ANP 8.91473
322 5VZ0 ADP 8.91473
323 4Y85 499 8.91473
324 3Q60 ATP 8.91473
325 3K5I ADP 8.91473
326 3K5I AIR 8.91473
327 5A6N U7E 9.30233
328 2Z7R STU 9.30233
329 4X7Q 3YR 9.30233
330 4PNI KQQ 9.30233
331 4L9I 8PR 9.30233
332 4MV1 ADP 9.30233
333 5UKL SIX 9.67742
334 2YAB AMP 9.68992
335 5DMZ ADP 9.68992
336 3EKK GS2 9.68992
337 3BU5 ATP 9.68992
338 5N87 N66 9.68992
339 1IR3 ANP 9.68992
340 3C0G 3AM 9.68992
341 4AU8 Z3R 9.68992
342 4R78 AMP 9.68992
343 2YRX AMP 9.68992
344 3FHI ANP 9.74026
345 2WU6 DKI 10.0775
346 4JR7 GNP 10.0775
347 5CKW ANP 10.0775
348 3PP0 03Q 10.0775
349 1M0W ANP 10.0775
350 5Z84 CHD 10.0917
351 2BPM 529 10.4651
352 6GUE FB8 10.4651
353 2XMY CDK 10.4651
354 4CFU 2WC 10.4651
355 5VC5 96M 10.4651
356 4IDT T28 10.4651
357 4BCN T9N 10.4651
358 4U0I 0LI 10.4651
359 2WEI VGG 10.4651
360 4BCQ TJF 10.4651
361 4BCM T7Z 10.4651
362 5LMK 6ZK 10.4651
363 2PVN P63 10.8527
364 6CMJ F6J 10.8527
365 5MY8 RXZ 10.8527
366 4OAV ACP 10.8527
367 2ZV2 609 10.8527
368 1V0O INR 10.8527
369 4NZN 2OU 10.8527
370 4NZN ANP 10.8527
371 3GQI ACP 11.0619
372 5G1X ADP 11.1111
373 3PE2 E1B 11.2403
374 3ORK AGS 11.2403
375 5OMY 9YE 11.2403
376 4G31 0WH 11.2403
377 3TDV GDP 11.2403
378 5YF9 NIO 11.2403
379 1T36 ADP 11.2403
380 4C2V YJA 11.3636
381 4C2W ANP 11.5385
382 4CRL C1I 11.6279
383 3TTI KBI 11.6279
384 4IZY 1J2 11.6279
385 4WHZ 3NL 11.6279
386 4UX9 ANP 11.6279
387 4USF 6UI 11.6279
388 3E7O 35F 11.6279
389 5JKG 6LF 11.6279
390 3PTG 932 11.6279
391 3OCP CMP 12.2302
392 3ZZS TRP 12.3077
393 4F9C 0SX 12.4031
394 4U44 3D9 12.4031
395 6CGD AKN 12.4031
396 6CGD GNP 12.4031
397 3SRV S19 12.7907
398 4FL3 ANP 12.7907
399 4F4P 0SB 12.7907
400 2BKK ADP 12.7907
401 3HMO STU 12.7907
402 4LRJ ANP 13.0178
403 4WW7 AMP 13.1783
404 5AX9 4KT 13.1783
405 2J7T 274 13.1783
406 5TO8 7FM 13.5659
407 1UNH IXM 13.5659
408 5AWM ANP 13.9535
409 5HCY 60D 14.3411
410 4Y8D 49J 14.7287
411 5Y80 IRE 14.7287
412 1PK8 ATP 14.7287
413 5JZJ AN2 15.1163
414 3KN5 ANP 15.1163
415 4AZW ATP 15.5039
416 1QAW TRP 16.2162
417 1ONI BEZ 17.3913
418 1OGX EQU 17.5573
419 3TM0 ANP 17.8295
420 3TM0 B31 17.8295
421 4ONA UW1 18.2171
422 1FFU CDP 18.4049
423 3O0G 3O0 18.7919
424 4BFM ANP 18.9922
425 6GZD LCI 18.9922
426 2CSN CKI 20.5426
427 4Q5H ANP 21.2644
428 2UYN 2KT 21.7054
429 5VCV 1N1 22.8682
430 3VPB ADP 23.2143
431 5C8W PCG 28.6713
432 5HQ0 LZ9 34.5238
433 6GU6 1QK 34.5238
Pocket No.: 2; Query (leader) PDB : 1ZTH; Ligand: ADP; Similar sites found with APoc: 22
This union binding pocket(no: 2) in the query (biounit: 1zth.bio1) has 16 residues
No: Leader PDB Ligand Sequence Similarity
1 1FKB RAP None
2 3S43 478 None
3 1MJH ATP None
4 3A76 SPD 1.13636
5 5JE8 NAD 1.55039
6 5NUF NAD 2.32558
7 4PZ6 GMP 2.32558
8 2HGS ADP 2.32558
9 5EJ2 NAD 2.32558
10 3VX3 ADP 2.41935
11 4H2D FMN 2.42424
12 6EAC ANP 2.71318
13 4LA7 A1O 3.87597
14 5JO1 6LM 4.86486
15 2Y88 2ER 5.7377
16 1I7M PUT 5.97015
17 5V1B 8UY 6.66667
18 5W10 CMP 7.17949
19 4J25 OGA 10.0437
20 2O4N TPV 11.1111
21 5L6G XYP 11.6279
22 3VPB GLU 23.2143
Pocket No.: 3; Query (leader) PDB : 1ZTH; Ligand: ADP; Similar sites found with APoc: 14
This union binding pocket(no: 3) in the query (biounit: 1zth.bio3) has 17 residues
No: Leader PDB Ligand Sequence Similarity
1 2OBF F83 2.32558
2 2C29 NAP 2.71318
3 2C29 DQH 2.71318
4 4FE2 ADP 2.7451
5 1OBD ATP 3.10078
6 5T2Z 017 5.05051
7 1OUK 084 5.42636
8 2EQA AMP 5.81395
9 4QM9 CYS 6.35838
10 2YC5 6BC 7.01754
11 4B2D SER 7.75194
12 3IES M24 8.91473
13 2OO8 RAJ 9.68992
14 6CS8 F9Y 12.0155
Pocket No.: 4; Query (leader) PDB : 1ZTH; Ligand: ADP; Similar sites found with APoc: 17
This union binding pocket(no: 4) in the query (biounit: 1zth.bio2) has 16 residues
No: Leader PDB Ligand Sequence Similarity
1 3HGM ATP None
2 1SMR PIV HIS PRO PHE HIS LPL TYR TYR SER 1.93798
3 4XVX P33 FDA 1.93798
4 3EAU NDP 2.71318
5 3EAU PDN 2.71318
6 3BP1 GUN 2.71318
7 3JRS A8S 2.88462
8 3TTM PUT 3.10078
9 5DJU FMN 4.13793
10 3ZGJ RMN 5.42636
11 4B2Z P5S 5.81395
12 3ZZQ TRP 6.15385
13 1N62 MCN 7.36434
14 4WVO 3UZ 8.28729
15 5UR6 8KM 8.28729
16 4LO2 GAL BGC 10.8527
17 3ZZL TRP 11.4286
APoc FAQ
Feedback