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Receptor
PDB id Resolution Class Description Source Keywords
1ZX5 2.3 Å EC: 5.-.-.- THE STRUCTURE OF A PUTATIVE MANNOSEPHOSPHATE ISOMERASE FROM ARCHAEOGLOBUS FULGIDUS ARCHAEOGLOBUS FULGIDUS MANNOSE 6-PHOSPHATE ISOMERASE ARCHAEOGLOBUS FULGIDUS STRUGENOMICS PSI PROTEIN STRUCTURE INITIATIVE MIDWEST CENTERSTRUCTURAL GENOMICS MCSG UNKNOWN FUNCTION
Ref.: THE STRUCTURE OF A PUTATIVE MANNOSEPHOSPHATE ISOMER ARCHAEOGLOBUS FULGIDUS TO BE PUBLISHED
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ACY A:502;
A:503;
A:504;
A:505;
A:506;
A:507;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
none;
submit data
60.052 C2 H4 O2 CC(=O...
EDO A:800;
A:801;
Invalid;
Invalid;
none;
none;
submit data
62.068 C2 H6 O2 C(CO)...
GOL A:700;
Invalid;
none;
submit data
92.094 C3 H8 O3 C(C(C...
LFR A:600;
Valid;
none;
submit data
180.156 C6 H12 O6 C([C@...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1ZX5 2.3 Å EC: 5.-.-.- THE STRUCTURE OF A PUTATIVE MANNOSEPHOSPHATE ISOMERASE FROM ARCHAEOGLOBUS FULGIDUS ARCHAEOGLOBUS FULGIDUS MANNOSE 6-PHOSPHATE ISOMERASE ARCHAEOGLOBUS FULGIDUS STRUGENOMICS PSI PROTEIN STRUCTURE INITIATIVE MIDWEST CENTERSTRUCTURAL GENOMICS MCSG UNKNOWN FUNCTION
Ref.: THE STRUCTURE OF A PUTATIVE MANNOSEPHOSPHATE ISOMER ARCHAEOGLOBUS FULGIDUS TO BE PUBLISHED
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 27 families.
1 1ZX5 - LFR C6 H12 O6 C([C@H]1[C....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 26 families.
1 1ZX5 - LFR C6 H12 O6 C([C@H]1[C....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 19 families.
1 1ZX5 - LFR C6 H12 O6 C([C@H]1[C....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: LFR; Similar ligands found: 12
No: Ligand ECFP6 Tc MDL keys Tc
1 FRU 1 1
2 SF6 1 1
3 LFR 1 1
4 PSV 1 1
5 SF9 1 1
6 F6P 0.564103 0.744186
7 TA6 0.564103 0.744186
8 FRU FRU 0.511111 0.888889
9 LBS 0.511111 0.888889
10 F1X 0.487805 0.744186
11 LRH 0.484848 0.882353
12 0UB 0.479167 0.888889
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1ZX5; Ligand: LFR; Similar sites found with APoc: 350
This union binding pocket(no: 1) in the query (biounit: 1zx5.bio1) has 9 residues
No: Leader PDB Ligand Sequence Similarity
1 1NZY BCA None
2 3JVH HHV None
3 5O1I 9GH None
4 3ZRM ZRM 0.666667
5 1JXZ BCA 1.11524
6 4YNM SAM 1.32743
7 6FDF SAH 1.33333
8 4QAR ADE 1.49254
9 5XKT GNP 1.5
10 2XOC ADP 1.53257
11 4CNG SAH 1.56863
12 3PN1 IVH 1.66667
13 5MW8 ATP 1.66667
14 4OH4 ANP 1.66667
15 3X01 AMP 1.66667
16 1NBU PH2 1.68067
17 2DT5 NAD 1.89573
18 2AHR NAP 1.9305
19 4R84 CSF 2
20 2CNE DFJ 2
21 3ZZH NLG 2
22 3PPM JG1 2
23 1MH1 GNP 2
24 1DY4 SNP 2
25 3CZ7 ACO 2
26 3VCY UD1 2
27 4CYI ATP 2
28 1F76 FMN 2
29 4UXL 5P8 2
30 5BV3 M7G 2
31 3BC1 GNP 2.05128
32 2Y6O 1N1 2.06186
33 1LO8 4CA 2.12766
34 4IWN GEK 2.18341
35 4EMV 0R9 2.21239
36 3TM0 ANP 2.28137
37 3TM0 B31 2.28137
38 1V7Z CRN 2.30769
39 3AKK ADP 2.33333
40 1GP6 SIN 2.33333
41 1GP6 DH2 2.33333
42 1GP6 QUE 2.33333
43 4HCX NDP 2.33333
44 3GWZ SAH 2.33333
45 3GXO SAH 2.33333
46 1ST0 GTG 2.33333
47 6GNF ADP 2.33333
48 5W7R 9Z7 2.33333
49 2PV7 NAD 2.33333
50 5W7R SAH 2.33333
51 4I94 ANP 2.33333
52 1UPT GTP 2.33918
53 2HRL SIA GAL SIA BGC NGA CEQ 2.3622
54 1YVD GNP 2.36686
55 1S4M LUM 2.38908
56 1S68 AMP 2.40964
57 1WG8 SAM 2.45614
58 1ION ADP 2.46914
59 1PN4 HDC 2.5
60 4ZS4 ATP 2.60586
61 5H2U 1N1 2.62172
62 5COU ATP 2.64706
63 3TY5 ADP 2.66344
64 5DY5 5GR 2.66667
65 2R3A SAM 2.66667
66 6C5B SAH 2.66667
67 1RKX NAD 2.66667
68 2VVL FAD 2.66667
69 2ZB3 NDP 2.66667
70 2RL1 UD1 2.66667
71 5JBX COA 2.68199
72 2RIF AMP 2.83688
73 4ZTE 4RL 2.8436
74 4F4P 0SB 2.9304
75 5UAO FAD 2.95749
76 5W5R PYR 3
77 4C2X NHW 3
78 5GQX GLC GLC GLC GLC GLC GLC GLC 3
79 1Q3Q ANP 3
80 4USF 6UI 3
81 3OTX AP5 3
82 4N70 2HX 3
83 4A6D SAM 3
84 5WKC FAD 3
85 1BZL GCG 3
86 3B2Q ATP 3
87 3FSY SCA 3
88 4A1O JLN 3
89 3GC8 B45 3
90 1P4A PCP 3.15789
91 3O7J 2AL 3.1746
92 5EY0 GTP 3.28467
93 3H11 ALA ILE GLU THR ASA 3.30882
94 2XK9 XK9 3.33333
95 5MLR NAP 3.33333
96 4ZDC CO8 3.33333
97 5U6C 7YS 3.33333
98 4I6H 1C8 3.33333
99 2VBF TPP 3.33333
100 4RPL FAD 3.33333
101 4RPL 3UC 3.33333
102 1DUB CAA 3.44828
103 4RRG A3T 3.5461
104 4GV8 DUP 3.5503
105 4YS0 ADP 3.66667
106 1IYK MIM 3.66667
107 3T7V SAM 3.66667
108 2YNE NHW 3.66667
109 2YNE YNE 3.66667
110 4D5G FAD 3.66667
111 4D5G TPP 3.66667
112 6A5K SAM 3.66667
113 1M5B BN1 3.66667
114 2NP9 YE1 3.66667
115 4PVD NDP 3.66667
116 5U19 SAH 3.66667
117 5U19 827 3.66667
118 2VN9 GVD 3.66667
119 2V7O DRN 3.66667
120 3GYQ SAM 3.67647
121 6GUE FB8 3.73134
122 1F5V FMN 3.75
123 4BCN T9N 3.81679
124 5EXT ADP 3.84615
125 2OFW ADX 3.84615
126 5LMK 6ZK 3.87597
127 4E03 ADP 3.8835
128 3E5H GNP 3.93258
129 4LYA ATP 3.9356
130 1EYR CDP 3.94737
131 5TT5 NAD 4
132 2D7D ADP 4
133 2UYQ SAM 4
134 3UBM COA 4
135 3DLS ADP 4
136 5C3R HMU 4
137 5C3R AKG 4
138 4IX4 ADP 4
139 5K8C NAD 4
140 1DL5 SAH 4
141 4UBT COA 4
142 1RLZ NAD 4
143 3KN5 ANP 4
144 5CGE 51F 4
145 4ZNL BEF ADP 4
146 4IZY 1J2 4
147 1F8G NAD 4
148 2G50 ALA 4
149 1VLH PNS 4.04624
150 4IPH 1FJ 4.06504
151 4CNE SAH 4.11985
152 5C2N NAG 4.16667
153 4GGL CJC 4.18605
154 1OS7 AKG 4.24028
155 1OS7 TAU 4.24028
156 3DNT ATP 4.31818
157 3TPV ADE 4.31818
158 3TKA SAM 4.33333
159 1WVG APR 4.33333
160 3IQE F42 4.33333
161 2F2U M77 4.33333
162 4I90 CHT 4.33333
163 5T8O 76Z 4.33333
164 3V8S 0HD 4.33333
165 5ERR ADP 4.53461
166 1IV2 CDP 4.60526
167 5WSY 7UC 4.62428
168 1TL2 NDG 4.66102
169 2A2C NG1 4.66667
170 2A2C ADP 4.66667
171 4U31 MVP 4.66667
172 1PFK ADP 4.66667
173 4V3C C 4.66667
174 5K7U SAM 4.66667
175 2IHK CSF 4.66667
176 5TT6 ATP 4.66667
177 2Z49 AMG 4.66667
178 3O9P MHI 4.66667
179 5IL1 SAM 4.66667
180 2XA2 UPG 4.66667
181 1XDY MTE 4.69799
182 1AV5 AP2 4.7619
183 1SQL GUN 4.79452
184 5DI3 GNP 4.86486
185 5L8L ADP 4.91228
186 5W7B PA1 PO4 FTT FTT GCS FTT PO4 KDO MYR 4.96454
187 2Q37 3AL 4.97238
188 2CDN ADP 4.97512
189 5C4L 4XR 5
190 4CC6 L5Y 5
191 3MGB GHP 3MY 3FG GHP GHP OMY 3FG 5
192 2QE0 NAP 5
193 5UR1 YY9 5
194 4LH7 1X8 5
195 4DFU QUE 5
196 1Q8Y ADE 5
197 6CMJ F6J 5
198 4K33 ACP 5
199 2ZV2 609 5.03356
200 1NW4 IMH 5.07246
201 1S8F GDP 5.08475
202 2VBU CDP 5.14706
203 3DCM SAM 5.20833
204 4K47 WMP 5.20833
205 1RC0 KT5 5.26316
206 4WKB TDI 5.32787
207 1KQN NAD 5.33333
208 3BEO UDP 5.33333
209 5TCI 79V 5.33333
210 6BSW UDP 5.33333
211 1G55 SAH 5.33333
212 3VHE 42Q 5.33333
213 2PUL ACP 5.33333
214 1DKU AP2 5.33333
215 6BSW CE6 5.33333
216 6H3O FAD 5.33333
217 3HAV ATP 5.35117
218 1J2J GTP 5.42169
219 3PCR GTP 5.55556
220 1FUT 2GP 5.66038
221 2CFM AMP 5.66667
222 5OGX FAD 5.66667
223 4CTA ATP 5.66667
224 4UUW AMP 5.66667
225 6CGD AKN 5.66667
226 6CGD GNP 5.66667
227 4WB7 ATP 5.66667
228 5GS9 ARG 5.66667
229 4GYI ADP 5.66667
230 1RDS GPC 5.71429
231 5A89 ADP 5.76923
232 5A89 FMN 5.76923
233 3MMG GLU THR VAL ARG PHE GLN SER ASP 5.80913
234 3GDH MGP 5.80913
235 1Z08 GNP 5.88235
236 4CRL C1I 5.96491
237 1B4P GPS 5.99078
238 5N6C NAD 6
239 5H41 IFM 6
240 4HI0 GDP 6.03015
241 3O0G 3O0 6.04027
242 1Z83 AP5 6.12245
243 6GBC AMP 6.33333
244 6FL8 ADP 6.33333
245 6FL8 TIY 6.33333
246 3CGD FAD 6.33333
247 3CGD NAD 6.33333
248 3CGD COA 6.33333
249 5TA6 79D 6.33333
250 2Q4H AMP 6.33333
251 3GUZ PAF 6.33333
252 3UDZ ADP 6.33333
253 3FC2 IBI 6.33333
254 5T0K SAM 6.40569
255 1TU3 GNP 6.43275
256 5JIY SAM 6.56934
257 3SLS 77D 6.66667
258 1RNT 2GP 6.73077
259 1W2D ADP 6.79245
260 5O96 SAM 6.93878
261 6EOM ALA LYS 7
262 3GNI ATP 7
263 4CL6 7SB 7.01754
264 4JGT PYR 7.02341
265 2BKK ADP 7.10059
266 3KIH GDL 7.2165
267 1YC5 NCA 7.31707
268 3NTD COA 7.33333
269 3NTA COA 7.33333
270 3NT6 COA 7.33333
271 5OKT 9XK 7.33333
272 2QHD DAO 7.37705
273 4XBA GMP 7.5
274 4XBA 5GP 7.5
275 2FR6 URI 7.53425
276 2FR6 CTN 7.53425
277 3KIF GDL 7.54717
278 3N1S 5GP 7.56302
279 3ICT COA 7.66667
280 3ICS COA 7.66667
281 5Y0T TAT 7.66667
282 1GS5 ANP 7.66667
283 1GS5 NLG 7.66667
284 1I8T FAD 7.66667
285 4IV9 FAD 7.66667
286 3C1X CKK 7.66667
287 4IEN GDP 7.97546
288 4QVX 3CQ 8
289 5YJF SAH 8.09859
290 5YJF 8WO 8.09859
291 2VJM COA 8.17757
292 1VGR COA 8.19672
293 4MZQ 1VU 8.33333
294 2VK4 TPP 8.33333
295 1UKZ AMP 8.37438
296 1UKZ ADP 8.37438
297 5KVM THR TYR PHE ALA VAL LEU MET VAL SER 8.42105
298 5VM6 9EG 8.66667
299 1BYG STU 8.66667
300 1HFS L04 8.75
301 2OL1 UMP 8.84354
302 1U7Z PMT 8.84956
303 3VPB ADP 8.92857
304 1QM5 PLP 9
305 3WB0 FEG 9.03614
306 4INI AMP 9.23077
307 5ZTN CUR 9.33333
308 5YF9 NIO 9.33333
309 5ENZ UDP 9.66667
310 5V22 SAH 9.76431
311 5OLZ T4E 10
312 1VGV UD1 10
313 2FSH ANP 10.3333
314 1ZPD DPX 10.3333
315 1W55 C 10.3333
316 5JLB SAH 10.3943
317 4FMU 0UM 10.4317
318 1YQZ FAD 11
319 4JGP PYR 11.0599
320 5JBE MAL 11.3333
321 1VQ2 DDN 11.399
322 5W6Y TRP 11.6667
323 4IE6 UN9 11.6667
324 1XDS SAM 11.6667
325 5VC5 96M 11.7647
326 1NHX PEP 12
327 1NHX FTB 12
328 2GK6 ADP 12
329 8CAT NDP 12
330 2DJH 3PD UM3 12.1739
331 3VSV XYS 12.3333
332 1QZZ SAM 12.3333
333 1Q7E MET 12.3333
334 2VSS ACO 13
335 4C8E C5P 13.7363
336 3RZ3 U94 14.2077
337 4CJN MUR 15.3333
338 4J75 TYM 15.6667
339 4K81 GTP 16.3743
340 1MHW BP4 CYS DAR TYR PEA 16.6667
341 6D5G FVD 16.7665
342 6D56 FVM 16.7665
343 6D59 FVJ 16.7665
344 6D5H FV7 16.7665
345 3DOE GTP 18.2292
346 5RHN 8BR 18.2609
347 5UPK GNP 18.3784
348 4LWA Q13 19.3333
349 1KSH GDP 24.7312
350 5WDR GNP 34.5029
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