Receptor
PDB id Resolution Class Description Source Keywords
1ZX5 2.3 Å EC: 5.-.-.- THE STRUCTURE OF A PUTATIVE MANNOSEPHOSPHATE ISOMERASE FROM ARCHAEOGLOBUS FULGIDUS ARCHAEOGLOBUS FULGIDUS MANNOSE 6-PHOSPHATE ISOMERASE ARCHAEOGLOBUS FULGIDUS STRUGENOMICS PSI PROTEIN STRUCTURE INITIATIVE MIDWEST CENTERSTRUCTURAL GENOMICS MCSG UNKNOWN FUNCTION
Ref.: THE STRUCTURE OF A PUTATIVE MANNOSEPHOSPHATE ISOMER ARCHAEOGLOBUS FULGIDUS TO BE PUBLISHED
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ACY A:502;
A:503;
A:504;
A:505;
A:506;
A:507;
 Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
 none;
none;
none;
none;
none;
none;
 submit data
60.052 C2 H4 O2 CC(=O...
EDO A:800;
A:801;
 Invalid;
Invalid;
 none;
none;
 submit data
62.068 C2 H6 O2 C(CO)...
GOL A:700;
 Invalid;
 none;
 submit data
92.094 C3 H8 O3 C(C(C...
LFR A:600;
 Valid;
 none;
 submit data
180.156 C6 H12 O6 C([C@...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1ZX5 2.3 Å EC: 5.-.-.- THE STRUCTURE OF A PUTATIVE MANNOSEPHOSPHATE ISOMERASE FROM ARCHAEOGLOBUS FULGIDUS ARCHAEOGLOBUS FULGIDUS MANNOSE 6-PHOSPHATE ISOMERASE ARCHAEOGLOBUS FULGIDUS STRUGENOMICS PSI PROTEIN STRUCTURE INITIATIVE MIDWEST CENTERSTRUCTURAL GENOMICS MCSG UNKNOWN FUNCTION
Ref.: THE STRUCTURE OF A PUTATIVE MANNOSEPHOSPHATE ISOMER ARCHAEOGLOBUS FULGIDUS TO BE PUBLISHED
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 30 families.
1 1ZX5 - LFR C6 H12 O6 C([C@H]1[C....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 29 families.
1 1ZX5 - LFR C6 H12 O6 C([C@H]1[C....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 21 families.
1 1ZX5 - LFR C6 H12 O6 C([C@H]1[C....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: LFR; Similar ligands found: 12
No: Ligand ECFP6 Tc MDL keys Tc
1 SF9 1 1
2 SF6 1 1
3 LFR 1 1
4 PSV 1 1
5 FRU 1 1
6 TA6 0.564103 0.744186
7 F6P 0.564103 0.744186
8 F1X 0.487805 0.744186
9 LRH 0.484848 0.882353
10 FRU FRU FRU 0.479167 0.888889
11 FRU FRU FRU FRU 0.479167 0.888889
12 Z9N GLC 0.44 0.864865
Similar Ligands (3D)
Ligand no: 1; Ligand: LFR; Similar ligands found: 479
No: Ligand Similarity coefficient
1 6LW 0.9629
2 AHR 0.9501
3 MBG 0.9431
4 AH8 0.9431
5 XYP 0.9405
6 GLC 0.9404
7 V55 0.9318
8 CNL 0.9279
9 7VJ 0.9253
10 3Z7 0.9252
11 3XX 0.9224
12 4HM 0.9213
13 BDF 0.9208
14 ARW 0.9202
15 GYE 0.9201
16 C2U 0.9199
17 GTL 0.9198
18 5RG 0.9183
19 9MG 0.9175
20 TLA 0.9172
21 54G 0.9166
22 YIO 0.9163
23 GTQ 0.9162
24 5M0 0.9161
25 3DM 0.9160
26 SOE 0.9157
27 GAL 0.9148
28 FOT 0.9145
29 GLA 0.9145
30 2FG 0.9144
31 B0D 0.9143
32 I3A 0.9138
33 IJZ 0.9133
34 KDF 0.9132
35 UEG 0.9129
36 RBL 0.9124
37 GUN 0.9123
38 MAN 0.9112
39 XAN 0.9105
40 1GN 0.9103
41 4PW 0.9097
42 149 0.9094
43 Q88 0.9093
44 CGB 0.9089
45 9DG 0.9087
46 RIP 0.9086
47 EUG 0.9086
48 HJP 0.9084
49 HIO 0.9081
50 X6X 0.9077
51 5MK 0.9076
52 ZZT 0.9072
53 4P0 0.9072
54 4M4 0.9068
55 MFU 0.9066
56 3R9 0.9065
57 DIU 0.9064
58 M1E 0.9061
59 NSP 0.9055
60 BMA 0.9053
61 9TZ 0.9052
62 Z6J 0.9052
63 VNL 0.9048
64 RUU 0.9048
65 FUL 0.9046
66 FHN 0.9045
67 RM4 0.9044
68 FA1 0.9044
69 XLS 0.9043
70 I2M 0.9040
71 OAF 0.9040
72 8S0 0.9037
73 7MH 0.9037
74 FUB 0.9035
75 7HQ 0.9032
76 FCB 0.9029
77 RNS 0.9027
78 7VS 0.9027
79 G3F 0.9026
80 KOJ 0.9023
81 AGK 0.9022
82 WBU 0.9018
83 AUD 0.9015
84 IUP 0.9015
85 GAF 0.9013
86 BDR 0.9011
87 T6C 0.9011
88 ASC 0.9008
89 SOR 0.9007
90 IF7 0.9003
91 P4B 0.9003
92 3NT 0.9002
93 H76 0.9000
94 GIF 0.8998
95 5DI 0.8998
96 RNT 0.8997
97 24B 0.8996
98 FH2 0.8996
99 2MN 0.8996
100 RAM 0.8992
101 HXX 0.8992
102 FDK 0.8991
103 GIV 0.8989
104 URF 0.8989
105 DGJ 0.8986
106 BGC 0.8985
107 OMD 0.8984
108 NDM 0.8980
109 6CS 0.8976
110 GTZ 0.8976
111 SEJ 0.8975
112 NMJ 0.8975
113 DIE 0.8974
114 VOH 0.8970
115 EOL 0.8969
116 NFQ 0.8965
117 ZWZ 0.8965
118 II6 0.8963
119 JZ3 0.8963
120 C2A 0.8962
121 8VN 0.8961
122 IPZ 0.8959
123 IFM 0.8959
124 ADE 0.8959
125 IFL 0.8957
126 PXL 0.8957
127 DBX 0.8956
128 6M4 0.8954
129 GLF 0.8954
130 7D2 0.8953
131 HMU 0.8953
132 1LN 0.8952
133 NOJ 0.8951
134 42C 0.8951
135 SAL 0.8951
136 7B4 0.8950
137 F31 0.8950
138 FUF 0.8949
139 SDD 0.8945
140 NCD 0.8943
141 ASO 0.8943
142 AFR 0.8941
143 0R0 0.8940
144 F0J 0.8940
145 2GS 0.8938
146 XYS 0.8937
147 F05 0.8937
148 KIB 0.8933
149 329 0.8932
150 DMJ 0.8930
151 0MK 0.8929
152 RIB 0.8926
153 261 0.8926
154 FUC 0.8925
155 3F0 0.8919
156 FLC 0.8916
157 FA6 0.8915
158 Q6T 0.8915
159 MWP 0.8915
160 MMA 0.8914
161 ALL 0.8912
162 HPA 0.8911
163 M1Q 0.8909
164 PAF 0.8908
165 G4D 0.8907
166 CIT 0.8907
167 KPL 0.8906
168 FCA 0.8902
169 R8S 0.8902
170 3HA 0.8900
171 TAR 0.8898
172 H7Y 0.8892
173 12M 0.8890
174 AMG 0.8888
175 2LP 0.8887
176 KDG 0.8887
177 DRL 0.8886
178 BE2 0.8886
179 3M0 0.8885
180 ARA 0.8884
181 QIC 0.8884
182 4XR 0.8881
183 AI2 0.8880
184 ABE 0.8879
185 XUL 0.8876
186 MNM 0.8875
187 ORO 0.8874
188 AKH 0.8874
189 GZL 0.8874
190 AN0 0.8873
191 SFU 0.8873
192 G2F 0.8873
193 RB5 0.8872
194 NK 0.8872
195 T9G 0.8872
196 KBB 0.8870
197 B53 0.8870
198 ARB 0.8869
199 82I 0.8868
200 LGC 0.8867
201 N8P 0.8867
202 F81 0.8866
203 64K 0.8865
204 5WX 0.8864
205 HX3 0.8864
206 2H5 0.8864
207 7HP 0.8862
208 ENL 0.8861
209 4ZC 0.8861
210 GOO 0.8860
211 O7U 0.8859
212 2DR 0.8858
213 FPY 0.8858
214 DFB 0.8857
215 DBH 0.8855
216 R2B 0.8854
217 DZX 0.8854
218 DOR 0.8852
219 INO 0.8851
220 53C 0.8850
221 XYL 0.8849
222 DHB 0.8847
223 3U4 0.8845
224 LYL 0.8844
225 EYK 0.8843
226 M0W 0.8843
227 PXM 0.8843
228 YHO 0.8841
229 SRT 0.8839
230 GCO 0.8838
231 GLY PRO 0.8838
232 7A2 0.8838
233 ZZ3 0.8835
234 0W8 0.8835
235 GCS 0.8835
236 AZF 0.8834
237 SR1 0.8834
238 3R6 0.8831
239 XQG 0.8828
240 DFU 0.8826
241 BK9 0.8826
242 7WR 0.8825
243 TBP 0.8825
244 GXL 0.8823
245 2EC 0.8823
246 41K 0.8823
247 FP1 0.8822
248 3DO 0.8822
249 ES6 0.8820
250 BTE 0.8819
251 OW4 0.8819
252 GT0 0.8817
253 PA1 0.8817
254 HHA 0.8817
255 MSN 0.8815
256 DMV 0.8815
257 286 0.8815
258 FUD 0.8814
259 SX1 0.8814
260 32O 0.8814
261 4AV 0.8813
262 MLT 0.8813
263 MYJ 0.8812
264 PBE 0.8810
265 R1X 0.8809
266 3SK 0.8808
267 DHK 0.8807
268 3MG 0.8806
269 FA3 0.8803
270 AOS 0.8798
271 OXZ 0.8797
272 ADA 0.8797
273 G5V 0.8794
274 ROR 0.8792
275 ECG 0.8792
276 KJY 0.8790
277 IPM 0.8789
278 P9P 0.8789
279 JKE 0.8788
280 JIF 0.8788
281 EXO 0.8787
282 4CS 0.8787
283 1AL 0.8787
284 EMZ 0.8787
285 OVP 0.8782
286 2A7 0.8781
287 TMH 0.8780
288 8VE 0.8780
289 4TE 0.8779
290 MEV 0.8778
291 1DW 0.8778
292 BDP 0.8778
293 AS3 0.8777
294 8WQ 0.8777
295 BFM 0.8775
296 6KX 0.8774
297 42A 0.8771
298 HLZ 0.8771
299 WOO 0.8770
300 PSJ 0.8769
301 K5W 0.8766
302 34V 0.8765
303 DQA 0.8764
304 UNC 0.8762
305 CBF 0.8761
306 R8A 0.8760
307 VNJ 0.8759
308 GOX 0.8757
309 LZM 0.8754
310 7ME 0.8753
311 S76 0.8752
312 25W 0.8752
313 HQ9 0.8751
314 SKM 0.8750
315 SHG 0.8750
316 35C 0.8750
317 SC2 0.8750
318 5WY 0.8748
319 AEH 0.8745
320 FE DB1 0.8745
321 NTM 0.8745
322 LDP 0.8743
323 9SE 0.8743
324 KP6 0.8742
325 FSW 0.8738
326 LCN 0.8738
327 34D 0.8738
328 MFB 0.8737
329 3DY 0.8737
330 SVD 0.8736
331 SHA 0.8736
332 G8M 0.8736
333 JZ1 0.8734
334 23A 0.8733
335 ICT 0.8733
336 IP0 0.8732
337 PRZ 0.8731
338 ISD 0.8730
339 SRO 0.8729
340 GLU 0.8729
341 2AS 0.8729
342 KBG 0.8725
343 3OC 0.8725
344 GIO 0.8722
345 JZ4 0.8720
346 TWO 0.8718
347 GTR 0.8717
348 DBJ 0.8715
349 CRN 0.8715
350 3IT 0.8714
351 AZA 0.8713
352 HA7 0.8710
353 G6D 0.8705
354 TFU 0.8703
355 GV9 0.8702
356 HPY 0.8701
357 AIN 0.8698
358 JFJ 0.8695
359 6AP 0.8694
360 EV0 0.8693
361 V6F 0.8693
362 AOR 0.8693
363 9PY 0.8690
364 2XX 0.8689
365 YTB 0.8685
366 1U6 0.8684
367 8GC 0.8682
368 XXR 0.8681
369 M2H 0.8678
370 YQA 0.8676
371 94B 0.8675
372 4HO 0.8675
373 ZXD 0.8675
374 1WD 0.8675
375 MZG 0.8673
376 TRA 0.8672
377 5ZZ 0.8672
378 MWM 0.8672
379 MIG 0.8672
380 2YU 0.8671
381 YH7 0.8669
382 7A3 0.8668
383 2PG 0.8668
384 EDG 0.8668
385 GCV 0.8664
386 A1U 0.8660
387 K6H 0.8657
388 A2F 0.8657
389 MUC 0.8655
390 3V4 0.8653
391 XSP 0.8652
392 PRY 0.8650
393 4ZE 0.8649
394 SWA 0.8649
395 TM7 0.8649
396 FPK 0.8649
397 948 0.8649
398 BSX 0.8648
399 DX4 0.8647
400 ES0 0.8647
401 GLN 0.8646
402 4XV 0.8645
403 QM1 0.8645
404 5XB 0.8643
405 KDO 0.8642
406 TDR 0.8641
407 XBZ 0.8641
408 7MU 0.8640
409 ADK 0.8638
410 5JC 0.8638
411 KIA 0.8637
412 MCT 0.8636
413 NOY 0.8636
414 2AC 0.8635
415 1MC 0.8631
416 CWM 0.8630
417 2A9 0.8630
418 SKG 0.8629
419 27Y 0.8628
420 141 0.8628
421 6GU 0.8627
422 34A 0.8627
423 4CL 0.8625
424 CAX 0.8625
425 IGA 0.8625
426 BR9 0.8624
427 0LH 0.8623
428 XYD 0.8620
429 ICP 0.8620
430 HT4 0.8620
431 IMR 0.8619
432 TSS 0.8618
433 PFL 0.8617
434 4JJ 0.8615
435 2MP 0.8614
436 5MH 0.8614
437 MWJ 0.8610
438 JZ2 0.8610
439 ZB1 0.8610
440 13P 0.8608
441 47J 0.8604
442 4XS 0.8604
443 PHT 0.8600
444 9HX 0.8600
445 FDB 0.8599
446 23J 0.8596
447 5UC 0.8592
448 EJZ 0.8592
449 45L 0.8591
450 XXG 0.8588
451 Y8I 0.8585
452 ASP 0.8584
453 4SV 0.8583
454 INS 0.8580
455 SVN 0.8580
456 TH0 0.8578
457 THE 0.8577
458 1AB 0.8577
459 43M 0.8568
460 15L 0.8567
461 9DA 0.8565
462 069 0.8565
463 R1P 0.8560
464 MZB 0.8560
465 290 0.8560
466 4JO 0.8560
467 8EW 0.8559
468 9EW 0.8559
469 L3Q 0.8558
470 NEQ 0.8555
471 JBE 0.8554
472 10L 0.8554
473 98J 0.8553
474 PM6 0.8553
475 ES4 0.8547
476 4RW 0.8546
477 M1A 0.8526
478 SJ5 0.8518
479 3MA 0.8510
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1ZX5; Ligand: LFR; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 1zx5.bio1) has 9 residues
No: Leader PDB Ligand Sequence Similarity
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