Receptor
PDB id Resolution Class Description Source Keywords
1ZY7 1.7 Å EC: 3.-.-.- CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF AN ADENOSINE DE THAT ACTS ON RNA (HADAR2) BOUND TO INOSITOL HEXAKISPHOSPHAT HOMO SAPIENS ALPHA/BETA DEAMINASE MOTIF ZINC COORDINATION IONSITOL HEXAKISPHOSPHATE HYDROLASE
Ref.: INOSITOL HEXAKISPHOSPHATE IS BOUND IN THE ADAR2 COR REQUIRED FOR RNA EDITING. SCIENCE V. 309 1534 2005
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
IHP A:901;
B:902;
 Valid;
Valid;
 none;
none;
 submit data
660.035 C6 H18 O24 P6 C1(C(...
SO4 B:903;
 Invalid;
 none;
 submit data
96.063 O4 S [O-]S...
ZN A:801;
B:802;
 Part of Protein;
Part of Protein;
 none;
none;
 submit data
65.409 Zn [Zn+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1ZY7 1.7 Å EC: 3.-.-.- CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF AN ADENOSINE DE THAT ACTS ON RNA (HADAR2) BOUND TO INOSITOL HEXAKISPHOSPHAT HOMO SAPIENS ALPHA/BETA DEAMINASE MOTIF ZINC COORDINATION IONSITOL HEXAKISPHOSPHATE HYDROLASE
Ref.: INOSITOL HEXAKISPHOSPHATE IS BOUND IN THE ADAR2 COR REQUIRED FOR RNA EDITING. SCIENCE V. 309 1534 2005
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 312 families.
1 1ZY7 - IHP C6 H18 O24 P6 C1(C(C(C(C....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 261 families.
1 1ZY7 - IHP C6 H18 O24 P6 C1(C(C(C(C....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 214 families.
1 1ZY7 - IHP C6 H18 O24 P6 C1(C(C(C(C....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: IHP; Similar ligands found: 24
No: Ligand ECFP6 Tc MDL keys Tc
1 IHP 1 1
2 I6P 1 1
3 I5P 0.652174 1
4 5MY 0.652174 1
5 5IP 0.652174 1
6 IP5 0.652174 1
7 I0P 0.608696 0.965517
8 O81 0.6 0.965517
9 2YN 0.6 0.965517
10 I7P 0.6 0.965517
11 I8P 0.6 0.965517
12 I4P 0.571429 1
13 5A2 0.555556 0.8
14 4WZ 0.555556 0.8
15 5A3 0.555556 0.8
16 2IP 0.545455 0.933333
17 4IP 0.538462 0.965517
18 ITP 0.52 0.933333
19 IP2 0.5 0.933333
20 I3S 0.481481 0.933333
21 I3P 0.481481 0.933333
22 I4D 0.48 0.9
23 0EJ 0.46875 0.823529
24 4WY 0.454545 0.8
Similar Ligands (3D)
Ligand no: 1; Ligand: IHP; Similar ligands found: 1
No: Ligand Similarity coefficient
1 IHS 0.9562
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1ZY7; Ligand: IHP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 1zy7.bio2) has 21 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 2; Query (leader) PDB : 1ZY7; Ligand: IHP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 1zy7.bio1) has 20 residues
No: Leader PDB Ligand Sequence Similarity
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