Receptor
PDB id Resolution Class Description Source Keywords
1a8b 1.9 Å NON-ENZYME: OTHER RAT ANNEXIN V COMPLEXED WITH GLYCEROPHOSPHOETHANOLAMINE RATTUS NORVEGICUS PHOSPHOLIPID ANALOG CALCIUM BINDING PROTEIN MEMBRANE BINDING PROTEIN
Ref.: CA(2+)-BRIDGING MECHANISM AND PHOSPHOLIPID HEAD GROUP RECOGNITION IN THE MEMBRANE-BINDING PROTEIN ANNEXIN V. NAT.STRUCT.BIOL. V. 2 968 1995
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
CA A:401;
A:402;
A:403;
A:404;
A:405;
A:406;
A:407;
A:408;
A:409;
A:410;
 Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
 none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
 submit data
40.078 Ca [Ca+2...
GPE A:999;
 Valid;
 none;
 submit data
215.142 C5 H14 N O6 P C(CO[...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1G5N 1.9 Å NON-ENZYME: OTHER ANNEXIN V COMPLEX WITH HEPARIN OLIGOSACCHARIDES RATTUS NORVEGICUS HELIX-BUNDLE MEMBRANE BINDING HEPARIN HEPARAN SULFATE BLCLOTTING
Ref.: ANNEXIN V--HEPARIN OLIGOSACCHARIDE COMPLEX SUGGESTS SULFATE--MEDIATED ASSEMBLY ON CELL SURFACES. STRUCTURE V. 9 57 2001
Members (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1610 families.
1 1A8B - GPE C5 H14 N O6 P C(CO[P@](=....
2 1A8A - GSE C6 H14 N O8 P C([C@H](CO....
3 1G5N - SGN IDS SGN UAP n/a n/a
70% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1331 families.
1 1A8B - GPE C5 H14 N O6 P C(CO[P@](=....
2 1A8A - GSE C6 H14 N O8 P C([C@H](CO....
3 1G5N - SGN IDS SGN UAP n/a n/a
50% Homology Family (7)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1144 families.
1 6TWU Kd ~ 1 mM SER SER ARG THR ARG ARG GLU GLU GLN LEU n/a n/a
2 6TWX Kd ~ 2.5 mM SER SER ARG THR ARG ARG GLU TPO GLN LEU n/a n/a
3 2HYU - SGN IDS SGN UAP n/a n/a
4 2HYV - IDS SGN IDS SGN UAP n/a n/a
5 1A8B - GPE C5 H14 N O6 P C(CO[P@](=....
6 1A8A - GSE C6 H14 N O8 P C([C@H](CO....
7 1G5N - SGN IDS SGN UAP n/a n/a
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: GPE; Similar ligands found: 8
No: Ligand ECFP6 Tc MDL keys Tc
1 GPE 1 1
2 CH5 0.65 0.745098
3 GSE 0.522727 0.840909
4 G3P 0.514286 0.731707
5 1GP 0.514286 0.731707
6 LPX 0.440678 0.764706
7 GP9 0.421053 0.707317
8 OPE 0.4 0.853659
Similar Ligands (3D)
Ligand no: 1; Ligand: GPE; Similar ligands found: 19
No: Ligand Similarity coefficient
1 ASF 0.9215
2 AQK 0.9057
3 X1R 0.8988
4 DLT 0.8949
5 HNE 0.8903
6 GGG 0.8900
7 NIG 0.8855
8 381 0.8814
9 IC9 0.8814
10 2J3 0.8788
11 C26 0.8785
12 F6R 0.8775
13 PJL 0.8744
14 M1C 0.8697
15 GRQ 0.8686
16 KNA 0.8681
17 5TO 0.8651
18 DI9 0.8593
19 36M 0.8548
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1G5N; Ligand: SGN IDS SGN UAP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 1g5n.bio1) has 8 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 2; Query (leader) PDB : 1G5N; Ligand: SGN IDS SGN UAP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 1g5n.bio1) has 10 residues
No: Leader PDB Ligand Sequence Similarity
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