Receptor
PDB id Resolution Class Description Source Keywords
1u4l 2 Å NON-ENZYME: OTHER HUMAN RANTES COMPLEXED TO HEPARIN-DERIVED DISACCHARIDE I-S HOMO SAPIENS CHEMOATTRACTANT CYTOKINE CHEMOKINE RANTES GLYCOSAMINOGLYPROTEIN-HEPARIN DISACCHARIDE COMPLEX ATTRACTANT
Ref.: THE X-RAY STRUCTURE OF RANTES: HEPARIN-DERIVED DISA ALLOWS THE RATIONAL DESIGN OF CHEMOKINE INHIBITORS. STRUCTURE V. 12 2081 2004
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ACY B:201;
 Invalid;
 none;
 submit data
60.052 C2 H4 O2 CC(=O...
SGN UAP C:1;
 Valid;
 none;
 submit data
575.454 n/a S(=O)...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1U4L 2 Å NON-ENZYME: OTHER HUMAN RANTES COMPLEXED TO HEPARIN-DERIVED DISACCHARIDE I-S HOMO SAPIENS CHEMOATTRACTANT CYTOKINE CHEMOKINE RANTES GLYCOSAMINOGLYPROTEIN-HEPARIN DISACCHARIDE COMPLEX ATTRACTANT
Ref.: THE X-RAY STRUCTURE OF RANTES: HEPARIN-DERIVED DISA ALLOWS THE RATIONAL DESIGN OF CHEMOKINE INHIBITORS. STRUCTURE V. 12 2081 2004
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1610 families.
1 1U4L - SGN UAP n/a n/a
2 1U4M - GNS UAP n/a n/a
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1331 families.
1 1U4L - SGN UAP n/a n/a
2 1U4M - GNS UAP n/a n/a
50% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1144 families.
1 1U4L - SGN UAP n/a n/a
2 1U4M - GNS UAP n/a n/a
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: SGN UAP; Similar ligands found: 7
No: Ligand ECFP6 Tc MDL keys Tc
1 SGN UAP 1 1
2 SGN IDU 0.611111 0.924242
3 SGN IDS SGN UAP 0.482456 0.925373
4 SGN IDS SGN IDS SGN UAP 0.482456 0.925373
5 SGN IDS SGN IDS 0.476636 0.895522
6 SGN IDS SGN IDS SGN 0.464912 0.925373
7 GNS UAP 0.458333 0.925373
Similar Ligands (3D)
Ligand no: 1; Ligand: SGN UAP; Similar ligands found: 0
No: Ligand Similarity coefficient
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1U4L; Ligand: SGN UAP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 1u4l.bio1) has 10 residues
No: Leader PDB Ligand Sequence Similarity
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