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Receptor
PDB id Resolution Class Description Source Keywords
2A14 1.7 Å EC: 2.1.1.49 CRYSTAL STRUCTURE OF HUMAN INDOLETHYLAMINE N- METHYLTRANSFERASE WITH SAH HOMO SAPIENS SGCINMT STRUCTURAL GENOMICS STRUCTURAL GENOMICS CONSORTIUM TRANSFERASE
Ref.: THE CRYSTAL STRUCTURE OF HUMAN INDOLETHYLAMINE N-METHYLTRANSFERASE IN COMPLEX WITH SAH. TO BE PUBLISHED
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
SAH A:4001;
Valid;
none;
submit data
384.411 C14 H20 N6 O5 S c1nc(...
SO4 A:2003;
Invalid;
none;
submit data
96.063 O4 S [O-]S...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2A14 1.7 Å EC: 2.1.1.49 CRYSTAL STRUCTURE OF HUMAN INDOLETHYLAMINE N- METHYLTRANSFERASE WITH SAH HOMO SAPIENS SGCINMT STRUCTURAL GENOMICS STRUCTURAL GENOMICS CONSORTIUM TRANSFERASE
Ref.: THE CRYSTAL STRUCTURE OF HUMAN INDOLETHYLAMINE N-METHYLTRANSFERASE IN COMPLEX WITH SAH. TO BE PUBLISHED
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 2A14 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 2A14 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
50% Homology Family (36)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 3KPV Kd = 180 uM ADE C5 H5 N5 c1[nH]c2c(....
2 3KQV - SAH C14 H20 N6 O5 S c1nc(c2c(n....
3 3KR2 Kd = 7.2 uM ET2 C7 H6 F N3 c1cc2c(cc1....
4 3KQY Kd = 15 uM ES0 C7 H7 N3 O c1cc2c(c(c....
5 3KQP Kd = 380 uM ES5 C9 H8 N2 c1cc2cc(cc....
6 2G70 Ki = 17 nM HNT C10 H12 N2 O3 c1cc2c(cc1....
7 3KQS Kd = 6.3 uM AX7 C7 H7 N3 c1ccc2c(c1....
8 3KQO Kd = 140 uM ES4 C5 H3 Cl N4 c1[nH]c2c(....
9 3HCD - SAH C14 H20 N6 O5 S c1nc(c2c(n....
10 2G8N Ki = 0.063 uM F83 C16 H17 Cl N2 O3 S c1cc(ccc1N....
11 3HCB - SAH C14 H20 N6 O5 S c1nc(c2c(n....
12 3HCC Ki = 13 uM LT3 C12 H12 F3 N c1cc2c(c(c....
13 3KQW Kd = 97 uM ES9 C7 H5 Cl N2 c1cc2c(cc1....
14 2G72 Ki = 315 nM F21 C14 H19 F N2 O2 S2 c1cc2c(cc1....
15 3KQQ - SAH C14 H20 N6 O5 S c1nc(c2c(n....
16 3HCA - OTR C8 H11 N O2 c1cc(ccc1[....
17 3KPU Kd = 690 uM ES1 C9 H7 N O c1ccc2c(c1....
18 1YZ3 Ki = 1.55 nM SKA C9 H9 Cl2 N c1cc(c(c2c....
19 2AN4 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
20 2G71 Ki = 35 nM FTS C13 H16 F4 N2 O2 S c1cc2c(cc1....
21 1HNN Ki = 0.58 uM SKF C9 H12 N2 O2 S c1cc2c(cc1....
22 3KPW Kd = 14 uM 1SQ C9 H8 N2 c1ccc2c(c1....
23 3KR1 Kd = 1.8 uM VGD C7 H6 Cl N3 c1cc2c(cc1....
24 2AN3 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
25 3KPJ - SAH C14 H20 N6 O5 S c1nc(c2c(n....
26 3KQT Kd = 4.6 uM ES7 C8 H9 N3 Cn1c2ccccc....
27 2OBF Ki = 1.4 nM F83 C16 H17 Cl N2 O3 S c1cc(ccc1N....
28 2AN5 Ki = 2.1 uM TTL C10 H13 N O c1ccc2c(c1....
29 3KQM Kd = 170 uM ES3 C3 H3 Br N2 c1c(nc[nH]....
30 3KPY - SAH C14 H20 N6 O5 S c1nc(c2c(n....
31 5YJI ic50 = 5 uM 8WO C8 H12 N2 O2 CN1CC(=CC=....
32 5XVK ic50 = 9 uM 8GC C7 H9 N2 O C[n+]1cccc....
33 5YJF ic50 = 1.8 uM 8WO C8 H12 N2 O2 CN1CC(=CC=....
34 5XVQ ic50 = 9 uM 8GC C7 H9 N2 O C[n+]1cccc....
35 6CHH - F0P C24 H32 N8 O6 c1cc(cc(c1....
36 2A14 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: SAH; Similar ligands found: 211
No: Ligand ECFP6 Tc MDL keys Tc
1 SAH 1 1
2 5X8 0.759494 0.969697
3 A7D 0.734177 0.926471
4 TT8 0.709302 0.970588
5 DSH 0.692308 0.914286
6 SXZ 0.692308 0.916667
7 DTA 0.666667 0.857143
8 3DH 0.662338 0.869565
9 S8M 0.655556 0.901408
10 SFG 0.635294 0.954545
11 SA8 0.62069 0.915493
12 EEM 0.617977 0.890411
13 MTA 0.615385 0.869565
14 SAI 0.613636 0.955882
15 S7M 0.586957 0.916667
16 36A 0.586538 0.90411
17 K15 0.583333 0.878378
18 ADN 0.573333 0.84058
19 RAB 0.573333 0.84058
20 XYA 0.573333 0.84058
21 62X 0.572917 0.855263
22 5CD 0.571429 0.852941
23 0UM 0.5625 0.876712
24 5N5 0.558442 0.84058
25 A4D 0.551282 0.867647
26 SAM 0.537634 0.916667
27 SMM 0.536842 0.88
28 SSA 0.536842 0.712644
29 KB1 0.534653 0.902778
30 A5D 0.532609 0.857143
31 SIB 0.53125 0.928571
32 EP4 0.530864 0.819444
33 DSZ 0.530612 0.732558
34 GSU 0.53 0.752941
35 A 0.529412 0.763158
36 LMS 0.529412 0.694118
37 AMP 0.529412 0.763158
38 5CA 0.525773 0.712644
39 ME8 0.524752 0.8125
40 M2T 0.52439 0.821918
41 6RE 0.523256 0.824324
42 GJV 0.522727 0.813333
43 AAT 0.515789 0.863014
44 LSS 0.515152 0.696629
45 KAA 0.514852 0.727273
46 J7C 0.511364 0.835616
47 A5A 0.510417 0.697674
48 SON 0.505495 0.805195
49 SRP 0.505155 0.805195
50 F0P 0.504505 0.915493
51 54H 0.5 0.681818
52 VMS 0.5 0.681818
53 ADX 0.5 0.694118
54 CA0 0.5 0.769231
55 AMO 0.5 0.805195
56 5AL 0.5 0.779221
57 KH3 0.5 0.866667
58 NVA LMS 0.49505 0.707865
59 AHX 0.49505 0.753086
60 TSB 0.494949 0.689655
61 53H 0.494949 0.674157
62 G5A 0.494737 0.712644
63 ABM 0.494382 0.74359
64 A2D 0.494382 0.74359
65 ZAS 0.494253 0.808219
66 A6D 0.490196 0.759494
67 8QN 0.49 0.779221
68 GEK 0.49 0.956522
69 GAP 0.489583 0.769231
70 AN2 0.48913 0.734177
71 A3S 0.48913 0.884058
72 S4M 0.488889 0.831169
73 SRA 0.488636 0.746835
74 LAD 0.485437 0.810127
75 52H 0.484848 0.674157
76 A12 0.483516 0.759494
77 BA3 0.483516 0.74359
78 AP2 0.483516 0.759494
79 NEC 0.483146 0.788732
80 AOC 0.483146 0.842857
81 Y3J 0.481481 0.768116
82 VRT 0.479167 0.861111
83 50T 0.478723 0.734177
84 B4P 0.478261 0.74359
85 ADP 0.478261 0.74359
86 5AS 0.478261 0.655556
87 AP5 0.478261 0.74359
88 A3N 0.477778 0.830986
89 YSA 0.476636 0.712644
90 XAH 0.476636 0.768293
91 0XU 0.473684 0.897059
92 AT4 0.473118 0.7375
93 WAQ 0.471154 0.807692
94 NSS 0.470588 0.712644
95 5AD 0.468354 0.791045
96 AU1 0.468085 0.725
97 M33 0.468085 0.734177
98 MAO 0.467391 0.797468
99 TXA 0.466667 0.759494
100 NB8 0.466667 0.775
101 A3G 0.466667 0.871429
102 3AM 0.465909 0.727273
103 DAL AMP 0.465347 0.779221
104 8X1 0.465347 0.707865
105 A3T 0.463158 0.842857
106 ATP 0.463158 0.74359
107 HEJ 0.463158 0.74359
108 ACP 0.463158 0.746835
109 7D7 0.4625 0.785714
110 LEU LMS 0.461538 0.688889
111 9ZA 0.460784 0.740741
112 9ZD 0.460784 0.740741
113 5FA 0.458333 0.74359
114 AQP 0.458333 0.74359
115 AR6 0.458333 0.766234
116 APC 0.458333 0.759494
117 APR 0.458333 0.766234
118 PRX 0.458333 0.746835
119 F2R 0.457627 0.75
120 IOT 0.456897 0.761905
121 4AD 0.456311 0.794872
122 PAJ 0.456311 0.722892
123 WSA 0.45614 0.72093
124 YAP 0.453704 0.794872
125 8PZ 0.453704 0.712644
126 FA5 0.453704 0.805195
127 ADP PO3 0.453608 0.763158
128 ADV 0.453608 0.782051
129 NVA 2AD 0.453608 0.849315
130 SAP 0.453608 0.728395
131 AGS 0.453608 0.728395
132 RBY 0.453608 0.782051
133 AD9 0.453608 0.725
134 PTJ 0.45283 0.731707
135 MHZ 0.452632 0.797468
136 00A 0.451923 0.740741
137 A3P 0.451613 0.74026
138 YLP 0.451327 0.771084
139 7MD 0.45045 0.768293
140 ALF ADP 0.45 0.707317
141 ADP ALF 0.45 0.707317
142 2VA 0.447917 0.819444
143 OOB 0.446602 0.779221
144 ANP 0.444444 0.725
145 T99 0.444444 0.7375
146 ACQ 0.444444 0.746835
147 TAT 0.444444 0.7375
148 P5A 0.443396 0.719101
149 7D5 0.443182 0.708861
150 A1R 0.442308 0.7625
151 YLC 0.439655 0.790123
152 2AM 0.438202 0.717949
153 DLL 0.438095 0.779221
154 ARG AMP 0.4375 0.759036
155 A22 0.436893 0.734177
156 D3Y 0.436893 0.859155
157 ATF 0.435644 0.716049
158 MYR AMP 0.435185 0.746988
159 80F 0.434426 0.75
160 SO8 0.434343 0.808219
161 OAD 0.433962 0.769231
162 3UK 0.433962 0.769231
163 TAD 0.433628 0.765432
164 25A 0.432692 0.74359
165 6YZ 0.431373 0.746835
166 VO4 ADP 0.431373 0.734177
167 ADP VO4 0.431373 0.734177
168 9SN 0.431193 0.731707
169 TYM 0.431034 0.805195
170 B5V 0.429907 0.759494
171 PR8 0.429907 0.8
172 ADQ 0.428571 0.746835
173 YLB 0.42735 0.771084
174 9K8 0.425926 0.67033
175 1ZZ 0.425926 0.746988
176 FYA 0.425926 0.779221
177 3OD 0.425926 0.769231
178 PPS 0.425743 0.674419
179 MAP 0.423077 0.707317
180 A2P 0.421053 0.727273
181 4YB 0.421053 0.735632
182 9X8 0.420561 0.75
183 ADP BMA 0.420561 0.746835
184 TYR AMP 0.419643 0.794872
185 5SV 0.419048 0.731707
186 3NZ 0.416667 0.824324
187 YLA 0.416667 0.771084
188 8Q2 0.415254 0.688889
189 A3R 0.415094 0.7625
190 B5Y 0.414414 0.75
191 B5M 0.414414 0.75
192 48N 0.413793 0.753086
193 LPA AMP 0.413793 0.768293
194 AYB 0.413223 0.761905
195 ACK 0.413043 0.710526
196 QQY 0.413043 0.696203
197 BIS 0.412844 0.719512
198 JB6 0.412844 0.7625
199 PAP 0.41 0.730769
200 DQV 0.408696 0.75641
201 OVE 0.408602 0.7125
202 AMP DBH 0.40708 0.746835
203 4UV 0.40708 0.75
204 3AD 0.406977 0.852941
205 AF3 ADP 3PG 0.40678 0.743902
206 OMR 0.40678 0.738095
207 LAQ 0.405172 0.768293
208 A A 0.40367 0.74359
209 7C5 0.403509 0.789474
210 7MC 0.403361 0.75
211 4UU 0.4 0.75
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2A14; Ligand: SAH; Similar sites found with APoc: 457
This union binding pocket(no: 1) in the query (biounit: 2a14.bio1) has 24 residues
No: Leader PDB Ligand Sequence Similarity
1 2JK0 ASP None
2 1SQL GUN None
3 1NFQ NAI 1.15385
4 1IM8 SAI 1.22951
5 3DUW SAH 1.34529
6 6ECT SAM 1.52091
7 2GN4 NDP 1.52091
8 3GD4 NAD 1.52091
9 2GN4 UD1 1.52091
10 5THZ SAH 1.90114
11 2EJU SAH 1.90114
12 4DMG SAM 1.90114
13 5CUQ NSC 1.90114
14 4ITU NAI 1.90114
15 4ITU 1HS 1.90114
16 4GKV NAD 1.90114
17 1XG5 NAP 1.90114
18 1AE1 NAP 1.90114
19 1Q0S SAH 1.9305
20 1GEG NAD 1.95312
21 5T2U NAP 2.01613
22 1UAY ADN 2.06612
23 3GU3 SAH 2.28137
24 5FUB SAH 2.28137
25 5W7R SAH 2.28137
26 5X62 SAH 2.28137
27 5W7R 9Z7 2.28137
28 3EVG SAH 2.28137
29 3HB5 NAP 2.28137
30 2EB5 OXL 2.28137
31 3A4T SFG 2.28137
32 3HQ9 OXL 2.28137
33 3FPZ AHZ 2.28137
34 5YU3 NAD 2.28137
35 5YU3 PRO 2.28137
36 4C3Y FAD 2.28137
37 4C3Y ANB 2.28137
38 2P41 SAH 2.28137
39 3DXY SAM 2.29358
40 2VDV SAM 2.43902
41 1PR9 NAP 2.45902
42 3D3W NAP 2.45902
43 5LOG SAH 2.57511
44 1VE3 SAM 2.64317
45 5MPT SAH 2.6616
46 5DM1 5D7 2.6616
47 5DM1 SAH 2.6616
48 3LCV SAM 2.6616
49 1BC5 SAH 2.6616
50 2IZ1 ATR 2.6616
51 5BW4 SAM 2.6616
52 3FSY SCA 2.6616
53 2YX1 SFG 2.6616
54 1DL5 SAH 2.6616
55 3A4V NAD 2.6616
56 3A4V PYR 2.6616
57 3GRU AMP 2.6616
58 2PT9 2MH 2.6616
59 5HJM MTA 2.6616
60 1PZG A3D 2.6616
61 5WGR FAD 2.6616
62 4PLT NAI 2.6616
63 5K4W THR 2.6616
64 2PT9 S4M 2.6616
65 4PLG NAI 2.6616
66 4PLG OXM 2.6616
67 5K4W NAI 2.6616
68 5U5G 7VD 2.6616
69 2YY7 NAD 2.6616
70 5MIT NAP 2.6616
71 5MIT FAD 2.6616
72 3K6V CIT 2.6616
73 4JZ8 CIT 2.6616
74 1ZEM NAD 2.67176
75 1G60 SAM 2.69231
76 6CI9 NAP 2.7027
77 3HVJ 705 2.71493
78 5AN1 GSH 2.73973
79 3MB5 SAM 2.7451
80 5EEH SAH 2.92553
81 5EEH P9P 2.92553
82 2VWA PTY 2.9703
83 3FZG SAM 3
84 4KRG SAH 3.04183
85 4YAC NAI 3.04183
86 2FK8 SAM 3.04183
87 5DNK SAH 3.04183
88 3LST SAH 3.04183
89 4LHD GLY 3.04183
90 4M37 SAH 3.04183
91 5E1M SAH 3.04183
92 5E1M PRO PRO LYS ARG ILE ALA 3.04183
93 4BLW AMP 3.04183
94 2O07 SPD 3.04183
95 4BLW SAH 3.04183
96 5VN0 FAD 3.04183
97 4M38 SAH 3.04183
98 4UP4 NDG 3.04183
99 4UP4 NAG 3.04183
100 5ULP KB1 3.04183
101 5VN0 NAI 3.04183
102 6C5B SAH 3.04183
103 5WAN URA 3.04183
104 2O07 MTA 3.04183
105 2CDU FAD 3.04183
106 1V35 NAI 3.04183
107 2HK9 ATR 3.04183
108 4O1M NAD 3.04183
109 5EPO NAP 3.05344
110 4R6W PC 3.10078
111 4R6W SAH 3.10078
112 3A28 NAD 3.10078
113 4V3I ASP LEU THR ARG PRO 3.11284
114 3G6N MET ALA SER 3.14136
115 2Q46 NAP 3.16206
116 4RYV ZEA 3.22581
117 2JAP NDP 3.23887
118 2JAH NDP 3.23887
119 5Z2L NDP 3.26531
120 1QAN SAH 3.27869
121 5U83 ZN8 3.30189
122 5X3R 7Y3 3.41463
123 2ZWA SAH 3.42205
124 5ERG SAM 3.42205
125 3O7W SAM 3.42205
126 3FPF TNA 3.42205
127 3FPF MTA 3.42205
128 5GNX BGC 3.42205
129 6B3A SAM 3.42205
130 5JJR SAH 3.42205
131 6EOM ALA LYS 3.42205
132 3LTW HLZ 3.42205
133 3C6K SPD 3.42205
134 3C6K MTA 3.42205
135 2PX8 SAH 3.42205
136 3ABI NAD 3.42205
137 3BGD SAH 3.46154
138 3BGD PM6 3.46154
139 2HMT NAI 3.47222
140 5N5D SAM 3.53982
141 5ZW3 SAH 3.55556
142 5BSZ SAH 3.6
143 4NBU NAI 3.6
144 5THY SAH 3.7037
145 3KIF GDL 3.77358
146 1YXM ADE 3.80228
147 5FA5 MTA 3.80228
148 3GXO SAH 3.80228
149 4GQB 0XU 3.80228
150 3GWZ SAH 3.80228
151 4X60 SFG 3.80228
152 4X60 3XV 3.80228
153 5BJX NAD 3.80228
154 5BJX UDP 3.80228
155 1FP1 SAH 3.80228
156 5L1O 7PF 3.80228
157 3GCM 5GP 3.80228
158 4ARE FLC 3.80228
159 3I53 SAH 3.80228
160 1IY8 NAD 3.80228
161 2JHP SAH 3.80228
162 1NW5 SAM 3.80228
163 6BQ6 TER 3.80228
164 5O98 NAP 3.80228
165 5GT9 NAP 3.80228
166 2WG9 OCA 3.84615
167 3RJ5 NAD 3.93701
168 1I1N SAH 3.9823
169 1O97 AMP 4.16667
170 1RJD SAM 4.18251
171 5XNC MTA 4.18251
172 3PT9 SAH 4.18251
173 1SQF SAM 4.18251
174 2WA2 SAM 4.18251
175 4O0L NDP 4.18251
176 3A27 SAM 4.18251
177 5U19 SAH 4.18251
178 5U19 827 4.18251
179 1N2X SAM 4.18251
180 5FWA J7C 4.18251
181 2V6G NAP 4.18251
182 4N49 SAM 4.18251
183 4DCM SAM 4.18251
184 1FUR MLT 4.18251
185 1XHL NDP 4.18251
186 5MLR GRQ 4.18251
187 5MLR NAP 4.18251
188 2ZFU SAH 4.18605
189 2UZH IPE 4.24242
190 3LCC SAH 4.25532
191 5OVK NDP 4.29688
192 1XTP SAI 4.33071
193 2WSB NAD 4.33071
194 3FRH SAH 4.34783
195 3H2B SAH 4.4335
196 4QTU SAM 4.44444
197 2AOT SAH 4.56274
198 3VSE SAH 4.56274
199 5GWX SAM 4.56274
200 5GWX SAR 4.56274
201 4C4A SAH 4.56274
202 1JQD HSM 4.56274
203 6B92 SAH 4.56274
204 6FDF SAH 4.56274
205 3TKY SAH 4.56274
206 1JQD SAH 4.56274
207 2JJQ SAH 4.56274
208 1UWK NAD 4.56274
209 1UWK URO 4.56274
210 1KYZ SAH 4.56274
211 4Y9D NAI 4.56274
212 3EVF GTA 4.56274
213 3EVF SAH 4.56274
214 3NJ4 NAD 4.56274
215 4HA6 FAD 4.56274
216 4OHU 2TK 4.56274
217 4OHU NAD 4.56274
218 3X01 AMP 4.58015
219 5N53 8NB 4.61538
220 5MGZ SAH 4.66102
221 1TL2 NDG 4.66102
222 3LKZ SFG 4.6729
223 1L3I SAH 4.6875
224 6GFK SAH 4.78088
225 5JE0 AZ8 4.8583
226 5JE0 SAH 4.8583
227 1Q7B NAP 4.91803
228 3NDJ JHZ 4.94297
229 3NDJ SAH 4.94297
230 5T67 JHZ 4.94297
231 5T67 SAH 4.94297
232 3L9W AMP 4.94297
233 3L9W GSH 4.94297
234 1KGZ PRP 4.94297
235 1QZZ SAM 4.94297
236 1BDB NAD 4.94297
237 2BGM NAJ 4.94297
238 2HNK SAH 4.94297
239 2I7C AAT 4.947
240 3NZ1 3NY 4.98084
241 3Q87 SAM 5.29412
242 5JGL SAM 5.32319
243 4Y30 SAH 5.32319
244 4Y30 49L 5.32319
245 4AZW SAM 5.32319
246 5ICE SAH 5.32319
247 5ICE 2H4 5.32319
248 2Q1A 2KT 5.32319
249 1VL8 NAP 5.32319
250 3ELW SAM 5.32319
251 4FC7 NAP 5.32319
252 4FC7 COA 5.32319
253 1G0N NDP 5.32319
254 1G0N PHH 5.32319
255 3ELW GP3 5.32319
256 2ZIF SAM 5.32319
257 2ZXI FAD 5.32319
258 3P2E SAH 5.33333
259 3RKR NAP 5.34351
260 5M45 AMP 5.35714
261 5F2K SAH 5.43478
262 5F2K OCA 5.43478
263 3TN7 NJP 5.44747
264 5UFN SAH 5.46218
265 2XVM SAH 5.52764
266 5M58 SAH 5.65217
267 3H5N ATP 5.66572
268 5GM1 SAH 5.70342
269 6C8R SAH 5.70342
270 6C8R EQV 5.70342
271 1XDS SAM 5.70342
272 3TKA SAM 5.70342
273 3X0D SAH 5.70342
274 1XKQ NDP 5.70342
275 2NYA MGD 5.70342
276 2NVK FAD 5.70342
277 4YNU FAD 5.70342
278 1ZQ9 SAM 5.70342
279 1B09 PC 5.82524
280 4XUC SAM 5.9633
281 4XUC 43G 5.9633
282 3OFK SAH 6.01852
283 4PIO SAH 6.08365
284 4PIO AVI 6.08365
285 2UYQ SAM 6.08365
286 5O42 NAD 6.08365
287 5O42 BGC 6.08365
288 5O42 9JW 6.08365
289 1WG8 SAM 6.08365
290 3S1S SAH 6.08365
291 3H8V ATP 6.08365
292 5IL1 SAM 6.08365
293 2RH4 EMO 6.08365
294 3PFG TLO 6.08365
295 3PFG SAM 6.08365
296 5K7U SAM 6.08365
297 4D5G TPP 6.08365
298 4D5G FAD 6.08365
299 2PWY SAH 6.20155
300 5E9W SAH 6.46388
301 5E8J SAH 6.46388
302 5DLY 5D7 6.46388
303 5DLY SAH 6.46388
304 3GCZ SAM 6.46388
305 3M6W SAM 6.46388
306 3FUU ADN 6.46388
307 3VYW SAM 6.46388
308 3QWI CUE 6.46388
309 3QWI NAP 6.46388
310 1V59 NAD 6.46388
311 2PXX SAH 6.51163
312 5TVI O8N 6.52174
313 5YEC ATP 6.72269
314 3A25 SAM 6.84411
315 2JB2 FAD 6.84411
316 2JB2 PHE 6.84411
317 4RSL FAD 6.84411
318 2AE2 NAP 6.92308
319 2AE2 PTO 6.92308
320 4FHT DHB 7.00637
321 3GDH SAH 7.05394
322 1LSS NAD 7.14286
323 5W7K SAH 7.22433
324 6GKV SAH 7.22433
325 5KOK SAH 7.22433
326 5KOK S9T 7.22433
327 1P77 ATR 7.22433
328 5KOK R9T 7.22433
329 4A6D SAM 7.22433
330 5E72 SAM 7.22433
331 2E7Z MGD 7.22433
332 6EL3 NAP 7.22433
333 2BZG SAH 7.32759
334 2BD0 NAP 7.37705
335 3T7S SAM 7.46269
336 6D6Y SAH 7.60456
337 1UXG FUM 7.60456
338 1UXG NAD 7.60456
339 5CDH TLA 7.60456
340 1JG3 ADN 7.65957
341 1EJ0 SAM 7.77778
342 4OGQ 7PH 7.82123
343 1ZGA SAH 7.84314
344 4FZV SAM 7.94979
345 4M73 M72 7.98479
346 4M73 SAH 7.98479
347 3VC1 GST 7.98479
348 3VC1 SAH 7.98479
349 2EFJ SAH 7.98479
350 1G55 SAH 7.98479
351 2Q28 ADP 7.98479
352 4Z24 FAD 7.98479
353 1O68 KIV 7.98479
354 3KIH GDL 8.24742
355 3EGI ADP 8.25243
356 5F8F SFG 8.36502
357 1I9G SAM 8.36502
358 6DUB SAH 8.55856
359 5FTW SAH 8.59375
360 3MQ2 SAH 8.7156
361 4LWP SAH 8.74525
362 5MW4 5JU 8.74525
363 3QOX SAH 8.74525
364 3TLJ SAH 8.74525
365 3SJU NDP 8.74525
366 3CH6 311 8.74525
367 3CH6 NAP 8.74525
368 3JWH SAH 8.75576
369 1NV8 SAM 8.80282
370 1NV8 MEQ 8.80282
371 1FLJ GSH 8.84615
372 4POO SAM 9
373 2HYQ MAN MAN 9.01639
374 6ARJ SAH 9.12547
375 6ARJ BW4 9.12547
376 5DX8 SFG 9.12547
377 5DX1 SFG 9.12547
378 5DXA SFG 9.12547
379 5DWQ SFG 9.12547
380 2DPM SAM 9.12547
381 2XYQ SAH 9.12547
382 4L8F MTX 9.12547
383 5CIC 51R 9.25926
384 1XCL SAH 9.3617
385 4PNE SAH 9.5057
386 5WP4 SAH 9.5057
387 1E5Q NDP 9.5057
388 1U2Z SAH 9.5057
389 4CQM NAP 9.57854
390 3G89 SAM 9.63855
391 1WY7 SAH 9.66184
392 4URF NAD 9.67742
393 1UQX MMA 9.73451
394 1EFV AMP 9.80392
395 5WP5 SAH 9.88593
396 4KIB SAH 9.88593
397 1F3L SAH 9.88593
398 5XLX SAH 9.88593
399 4YMH SAH 10
400 4KRI SAH 10.2662
401 1L1E SAH 10.2662
402 4UCI SAM 10.2662
403 2GDZ NAD 10.2662
404 1FWV SGA MAG FUC 10.4478
405 5FEU NAP 10.6464
406 5FFF 5XC 10.8949
407 5FFF NAP 10.8949
408 3G2O SAM 11.0266
409 1P1C SAH 11.0553
410 1KPG SAH 11.4068
411 1KPH SAH 11.4068
412 3DMH SAM 11.4068
413 3DMH GMP 11.4068
414 4YAG NAI 11.4068
415 1R18 SAH 11.4537
416 5HWV MBN 11.5385
417 5W7M SAH 11.7871
418 1FP2 SAH 11.7871
419 1ZGS XMM 11.7871
420 1FP2 HMO 11.7871
421 2AG5 NAD 11.7886
422 2NXE SAM 11.811
423 2IMG MLT 11.9205
424 1JOT GAL A2G 12.0301
425 6ECU SAH 12.1673
426 1Z3C SA8 12.5475
427 4ONQ SFG 12.5475
428 4AKB GAL 12.782
429 4NEC SAH 12.9278
430 6ECW SAH 12.9278
431 5YF1 8V0 12.9278
432 5YF1 SFG 12.9278
433 6F5Z SAH 13.1148
434 2EG5 SAH 13.308
435 1JQ3 AAT 13.308
436 1JAC AMG 13.5338
437 1UGY GLA GLC 13.5338
438 1TOQ AMG 13.5338
439 1KUJ MMA 13.5338
440 1UGW GAL 13.5338
441 1WS4 GYP 13.5338
442 1UGY GLA BGC 13.5338
443 4OBW SAM 13.6187
444 1TPY SAH 13.6882
445 2Y69 CHD 13.75
446 4IWN GEK 14.4105
447 3BXO SAM 14.6444
448 4FN4 NAD 14.9606
449 4D42 W0I 15.2091
450 4D42 NAP 15.2091
451 4RVG TYD 15.5894
452 4RVG SAM 15.5894
453 3BPX SAL 18.9189
454 5C2N NAG 20.8333
455 5FA8 SAM 21.118
456 3OU2 SAH 23.8532
457 5DX0 SFG 40
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