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Receptor
PDB id Resolution Class Description Source Keywords
2AG4 1.8 Å NON-ENZYME: SIGNAL_HORMONE CRYSTAL STRUCTURE ANALYSIS OF GM2-ACTIVATOR PROTEIN COMPLEXE PHOSPHATIDYLCHOLINE HOMO SAPIENS COMPLEX OF SINGLE CHAIN LIPID AND FATTY ACIDS LIPID BINDING
Ref.: CRYSTAL STRUCTURE ANALYSIS OF PHOSPHATIDYLCHOLINE-GM2-ACTIVATOR PRODUCT COMPLEXES EVIDENCE FOR HYDROLASE ACTIVITY. BIOCHEMISTRY V. 44 13510 2005
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
IPA A:1501;
A:1502;
A:1503;
A:1506;
A:1508;
B:1504;
B:1505;
B:1507;
B:1510;
B:1511;
B:1512;
B:1513;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
submit data
60.095 C3 H8 O CC(C)...
LP3 A:2341;
B:2342;
Valid;
Valid;
none;
none;
submit data
524.691 C26 H55 N O7 P CCCCC...
OLA A:3628;
B:3629;
Valid;
Valid;
none;
none;
submit data
282.461 C18 H34 O2 CCCCC...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2AG4 1.8 Å NON-ENZYME: SIGNAL_HORMONE CRYSTAL STRUCTURE ANALYSIS OF GM2-ACTIVATOR PROTEIN COMPLEXE PHOSPHATIDYLCHOLINE HOMO SAPIENS COMPLEX OF SINGLE CHAIN LIPID AND FATTY ACIDS LIPID BINDING
Ref.: CRYSTAL STRUCTURE ANALYSIS OF PHOSPHATIDYLCHOLINE-GM2-ACTIVATOR PRODUCT COMPLEXES EVIDENCE FOR HYDROLASE ACTIVITY. BIOCHEMISTRY V. 44 13510 2005
Members (5)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 286 families.
1 2AG4 - LP3 C26 H55 N O7 P CCCCCCCCCC....
2 1TJJ - DAO C12 H24 O2 CCCCCCCCCC....
3 2AG9 - MYR C14 H28 O2 CCCCCCCCCC....
4 2AF9 - MYR C14 H28 O2 CCCCCCCCCC....
5 2AG2 - DAO C12 H24 O2 CCCCCCCCCC....
70% Homology Family (6)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 209 families.
1 2AG4 - LP3 C26 H55 N O7 P CCCCCCCCCC....
2 1TJJ - DAO C12 H24 O2 CCCCCCCCCC....
3 2AG9 - MYR C14 H28 O2 CCCCCCCCCC....
4 2AF9 - MYR C14 H28 O2 CCCCCCCCCC....
5 2AG2 - DAO C12 H24 O2 CCCCCCCCCC....
6 2AGC - MYR C14 H28 O2 CCCCCCCCCC....
50% Homology Family (6)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 174 families.
1 2AG4 - LP3 C26 H55 N O7 P CCCCCCCCCC....
2 1TJJ - DAO C12 H24 O2 CCCCCCCCCC....
3 2AG9 - MYR C14 H28 O2 CCCCCCCCCC....
4 2AF9 - MYR C14 H28 O2 CCCCCCCCCC....
5 2AG2 - DAO C12 H24 O2 CCCCCCCCCC....
6 2AGC - MYR C14 H28 O2 CCCCCCCCCC....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: LP3; Similar ligands found: 83
No: Ligand ECFP6 Tc MDL keys Tc
1 LAP 1 1
2 LPC 1 1
3 LP3 1 1
4 42H 0.863636 0.982143
5 PLD 0.685714 0.963636
6 6PL 0.685714 0.963636
7 LIO 0.685714 0.963636
8 HGP 0.685714 0.963636
9 HGX 0.685714 0.963636
10 PC7 0.685714 0.963636
11 NKN 0.645161 0.732143
12 NKO 0.645161 0.732143
13 XP5 0.633803 0.963636
14 PCW 0.607595 0.946429
15 LPE 0.602941 0.945455
16 PCK 0.592593 0.913793
17 S12 0.584416 0.75
18 CD4 0.583333 0.763636
19 CN5 0.575342 0.781818
20 NKP 0.56338 0.719298
21 PSC 0.55814 0.946429
22 PGM 0.557143 0.719298
23 CN6 0.538462 0.763636
24 8PE 0.533333 0.827586
25 PEF 0.533333 0.827586
26 PTY 0.533333 0.827586
27 PEV 0.533333 0.827586
28 PEH 0.533333 0.827586
29 9PE 0.526316 0.827586
30 PGT 0.526316 0.736842
31 LHG 0.526316 0.736842
32 PCF 0.525641 0.890909
33 PC1 0.525641 0.890909
34 MC3 0.525641 0.890909
35 CN3 0.525 0.763636
36 PEE 0.506494 0.844828
37 OPC 0.494253 0.929825
38 SPU 0.487179 0.836066
39 CH5 0.483871 0.824561
40 PX2 0.479452 0.745455
41 PX8 0.479452 0.745455
42 3XU 0.477273 0.84127
43 6OU 0.47619 0.813559
44 LOP 0.47619 0.813559
45 L9Q 0.47619 0.813559
46 P5S 0.475 0.779661
47 CDL 0.474359 0.727273
48 POV 0.471264 0.875
49 L9R 0.471264 0.875
50 D3D 0.470588 0.724138
51 PGW 0.470588 0.724138
52 LPP 0.465753 0.732143
53 F57 0.465753 0.732143
54 6PH 0.465753 0.732143
55 3PH 0.465753 0.732143
56 7PH 0.465753 0.732143
57 ZPE 0.465116 0.813559
58 PGV 0.465116 0.724138
59 DR9 0.465116 0.724138
60 PGK 0.45977 0.7
61 P6L 0.45977 0.724138
62 7P9 0.459459 0.732143
63 OZ2 0.454545 0.724138
64 PEK 0.444444 0.813559
65 3PC 0.444444 0.872727
66 DGG 0.444444 0.7
67 44G 0.435897 0.736842
68 GP7 0.434783 0.813559
69 43Y 0.432432 0.927273
70 PII 0.428571 0.66129
71 PD7 0.418919 0.732143
72 PIF 0.418605 0.650794
73 PIZ 0.41573 0.66129
74 DLP 0.414894 0.875
75 D21 0.414634 0.719298
76 M7U 0.414634 0.732143
77 3PE 0.409639 0.758621
78 8ND 0.407895 0.62069
79 P50 0.406593 0.779661
80 AGA 0.404762 0.736842
81 IP9 0.404494 0.66129
82 PIO 0.404494 0.650794
83 52N 0.404494 0.650794
Ligand no: 2; Ligand: OLA; Similar ligands found: 56
No: Ligand ECFP6 Tc MDL keys Tc
1 OLA 1 1
2 NER 1 1
3 ELA 1 1
4 VCA 0.939394 1
5 PAM 0.939394 1
6 MYZ 0.852941 0.954545
7 EIC 0.725 0.956522
8 DCR 0.71875 0.954545
9 F15 0.71875 0.954545
10 EW8 0.71875 0.954545
11 X90 0.71875 0.954545
12 TDA 0.71875 0.954545
13 DKA 0.71875 0.954545
14 STE 0.71875 0.954545
15 MYR 0.71875 0.954545
16 11A 0.71875 0.954545
17 DAO 0.71875 0.954545
18 KNA 0.71875 0.954545
19 PLM 0.71875 0.954545
20 F23 0.71875 0.954545
21 OCA 0.6875 0.954545
22 ODD 0.675 0.956522
23 RCL 0.625 0.88
24 LNL 0.613636 0.869565
25 SHV 0.606061 0.909091
26 KTC 0.605263 0.84
27 3X1 0.564103 0.863636
28 ODT 0.555556 0.826087
29 T25 0.54717 0.709677
30 AZ1 0.53125 0.615385
31 10X 0.529412 0.645161
32 10Y 0.529412 0.645161
33 6NA 0.529412 0.863636
34 OLB 0.519231 0.617647
35 OLC 0.519231 0.617647
36 243 0.519231 0.846154
37 MVC 0.490566 0.617647
38 ACD 0.488889 0.956522
39 VA 0.478261 0.692308
40 3LA 0.47619 0.769231
41 78M 0.471698 0.617647
42 78N 0.471698 0.617647
43 EOD 0.468085 0.677419
44 MPG 0.45283 0.617647
45 14V 0.444444 0.714286
46 LEA 0.441176 0.772727
47 T24 0.438596 0.769231
48 BRC 0.435897 0.64
49 14U 0.431818 0.678571
50 M12 0.428571 0.833333
51 UNA 0.421053 0.636364
52 OCD 0.421053 0.636364
53 8YP 0.421053 0.636364
54 D0G 0.4 0.913043
55 BNV 0.4 0.913043
56 BMJ 0.4 0.913043
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2AG4; Ligand: OLA; Similar sites found with APoc: 347
This union binding pocket(no: 1) in the query (biounit: 2ag4.bio2) has 54 residues
No: Leader PDB Ligand Sequence Similarity
1 3ZXE PGZ None
2 1MDC PLM None
3 4JH6 FCN None
4 3CM2 X23 None
5 5D48 L96 None
6 3G1Z AMP None
7 3OQJ 3CX None
8 2HO2 PRO PRO PRO PRO PRO PRO PRO PRO PRO LEU None
9 5F6U 5VK None
10 3HAV ATP None
11 3QUG GIX None
12 1Y7P RIP None
13 5HZ9 5M8 None
14 5OQW A4E None
15 3E85 BSU None
16 1LFO OLA None
17 4MOB ADP 1.21951
18 2E56 MYR 1.38889
19 2CJU PHX 1.65289
20 6EWZ APC 1.82927
21 2Z3U CRR 1.82927
22 1F5F DHT 1.82927
23 4PZ6 GMP 1.82927
24 4WVW SLT 2.08333
25 5HZ5 65X 2.23881
26 3ZW2 NAG GAL FUC 2.29885
27 1EWJ BLM 2.38095
28 4WCX MET 2.43902
29 5C5T AKG 2.43902
30 6F5U CQN 2.43902
31 1EB1 ASP TYR GLU PRO ILE PRO GLU GLU ALA PHE 2.43902
32 2OBD 2OB 2.43902
33 3A16 PXO 2.43902
34 5H9Q TD2 2.58065
35 4R38 RBF 2.85714
36 5DG2 GAL GLC 2.96296
37 3OYW TDG 2.98507
38 3FW3 ETS 3.04878
39 3KYF 5GP 5GP 3.04878
40 5T8U LPA 3.04878
41 3T4L ZEA 3.04878
42 3PUR 2HG 3.04878
43 6D6L FY4 3.04878
44 2QHV OC9 3.04878
45 2YG2 FLC 3.04878
46 1O9U ADZ 3.04878
47 2QHS OCA 3.04878
48 1MJT ITU 3.04878
49 4CSD MFU 3.04878
50 1RJW ETF 3.04878
51 2Z5Y HRM 3.04878
52 2YG2 S1P 3.04878
53 1I1E DM2 3.04878
54 4HIA FMN 3.04878
55 4M1U A2G MBG 3.04878
56 5C3R AKG 3.04878
57 5C3R HMU 3.04878
58 2GJ5 VD3 3.08642
59 3SAO DBH 3.125
60 3SAO NKN 3.125
61 4K55 H6P 3.22581
62 1GU3 BGC BGC BGC BGC BGC 3.3557
63 4WUJ FMN 3.40136
64 3NV3 GAL NAG MAN 3.62319
65 5WHT SIA GAL GLC 3.62319
66 5KJW 53C 3.65854
67 2G30 ALA ALA PHE 3.65854
68 2VFT SOR 3.65854
69 3RGA LSB 3.65854
70 1ZNY GDP 3.65854
71 6E1Q CFA 3.65854
72 4YVN EBS 3.65854
73 4XCB AKG 3.65854
74 4YGF AZM 3.65854
75 6GW4 CHO 3.65854
76 6GVZ CHO 3.65854
77 5OF1 SAL 3.65854
78 3R6K FUC GAL GLA 3.65854
79 5EJL C2E 3.65854
80 2OVD DAO 3.65854
81 1LNM DTX 3.65854
82 2OS2 OGA 3.65854
83 2P5B OGA 3.65854
84 3CF6 SP1 3.65854
85 4ZSI 4R1 3.65854
86 5H5A 6OU 3.65854
87 3V8S 0HD 3.65854
88 3CTL S6P 3.65854
89 1BHX ASP PHE GLU GLU ILE 3.80952
90 5T7I LAT NAG GAL 3.87097
91 3MTX PGT 3.97351
92 2AZ5 307 4.05405
93 1JIF CU BLM 4.09836
94 2VDF OCT 4.26829
95 2VL1 GLY GLY 4.26829
96 3JU6 ANP 4.26829
97 5YJS SAL 4.26829
98 4XMF HSM 4.26829
99 5D9G GLU ASN LEU TYR PHE GLN 4.26829
100 4ORR PE3 4.26829
101 4IMO PWZ 4.26829
102 1X8X TYR 4.26829
103 3A5Y KAA 4.26829
104 3TTZ 07N 4.26829
105 5T96 79J 4.26829
106 5HV7 RBL 4.26829
107 3W68 VIV 4.26829
108 5F7J ADE 4.26829
109 5LRT ADP 4.26829
110 1UNB AKG 4.26829
111 4V15 PLP 4.26829
112 5VAD PRO 4.26829
113 1UNB PN1 4.26829
114 3SLS 77D 4.26829
115 3A5Z KAA 4.26829
116 5FP4 YC8 4.26829
117 1C1L GAL BGC 4.37956
118 1IS3 LAT 4.44444
119 5CJ3 52G 4.44444
120 5BVT PAM 4.47761
121 2HKA C3S 4.61538
122 1ULE GLA GAL NAG 4.66667
123 5VM0 9EG 4.6875
124 4BG4 ADP 4.87805
125 3WV6 GAL BGC 4.87805
126 4D4U FUC NDG GAL FUC 4.87805
127 5JJU AMP 4.87805
128 2ET1 GLV 4.87805
129 1W2D ADP 4.87805
130 3WV6 GAL GLC 4.87805
131 3ZGJ RMN 4.87805
132 5TZO 7V7 4.87805
133 4NG2 OHN 4.87805
134 3E2M E2M 4.87805
135 1W96 S1A 4.87805
136 4CJN QNZ 4.87805
137 5V1B 8UY 4.87805
138 5J75 6GQ 4.87805
139 4D52 GIV 4.87805
140 4D4U FUC GAL NDG FUC 4.87805
141 3LVW GSH 4.87805
142 1KZN CBN 4.87805
143 3QP8 HL0 4.87805
144 1KDK DHT 4.87805
145 1I0B PEL 4.87805
146 3ACL 3F1 4.87805
147 2WA4 069 4.87805
148 5H9P TD2 5.06329
149 6GNO XDI 5.18518
150 1OPB RET 5.22388
151 4QYN RTL 5.26316
152 5NCF 8T5 5.30973
153 5HWV MBN 5.38462
154 2ZHL NAG GAL GAL NAG 5.40541
155 2Z6C FMN 5.42636
156 4RF7 ARG 5.4878
157 1SDW IYT 5.4878
158 1ELI PYC 5.4878
159 4NPL AKG 5.4878
160 4WOE ADP 5.4878
161 3P7N FMN 5.4878
162 1J3R 6PG 5.4878
163 4YRI 4JH 5.4878
164 5INJ 6C7 5.4878
165 1ZGS XMM 5.4878
166 2GQS C2R 5.4878
167 2Y3S TIR 5.4878
168 4OCT AKG 5.4878
169 5F7Y GLC GAL NAG GAL FUC A2G 5.4878
170 5F7N NAG GAL FUC FUC A2G 5.4878
171 4OUC 5ID 5.4878
172 3CBC DBS 5.55556
173 2BS5 BGC GAL FUC 5.55556
174 5VGS 9A7 5.73248
175 5VGS 9A4 5.73248
176 5ODY 9SK 5.7971
177 4RYV ZEA 5.80645
178 1SLT NDG GAL 5.97015
179 4IAW LIZ 6.09756
180 4KBA 1QM 6.09756
181 5G48 1FL 6.09756
182 2XG5 EC2 6.09756
183 2XG5 EC5 6.09756
184 1U6R ADP 6.09756
185 4H2X G5A 6.09756
186 1QY1 PRZ 6.09756
187 2GC0 PAN 6.09756
188 1GQG DCD 6.09756
189 4H2W AMP 6.09756
190 6FOF LAT 6.09756
191 5FLJ QUE 6.09756
192 3MF2 AMP 6.09756
193 6BU0 IHP 6.10687
194 3FW4 CAQ 6.17978
195 3VV1 GAL FUC 6.25
196 4TW7 37K 6.25
197 1KGI T4A 6.29921
198 4RLT FSE 6.32911
199 3QRC SCR 6.36943
200 1N9L FMN 6.42202
201 4YLZ LAT NAG GAL 6.53595
202 4L4J NAG NAG BMA MAN NAG 6.70732
203 5EO8 TFU 6.70732
204 2OJW ADP 6.70732
205 5FPE 3TR 6.70732
206 4MVK ACE VAL PHE PHE ALA GLU ASP NH2 6.70732
207 6CC0 EWM 6.70732
208 2YKL NLD 6.70732
209 5Y72 DST 6.70732
210 6E08 NAP 6.70732
211 5NKN LOC 6.70732
212 6FE1 V14 6.70732
213 4CQE CQE 6.70732
214 2NSX IFM 6.70732
215 4HWT 1B2 6.70732
216 4P7X YCP 6.70732
217 4P7X AKG 6.70732
218 4ZU4 4TG 6.75676
219 5KEW 6SB 6.94444
220 2GTF P1R 7.31707
221 1VRP ADP 7.31707
222 3GD9 GLC BGC BGC BGC 7.31707
223 5X7Q GLC GLC GLC GLC GLC 7.31707
224 5X7Q GLC GLC GLC GLC 7.31707
225 2J3M PRI 7.31707
226 2J3M ATP 7.31707
227 5XEG AKG 7.31707
228 6CAY ERG 7.31707
229 2RHQ GAX 7.31707
230 3IWD M2T 7.35294
231 5M6N 7H9 7.62712
232 4WN5 MVC 7.82609
233 5OCG 9R5 7.92683
234 1F9V ADP 7.92683
235 3B6R ADP 7.92683
236 4L9I 8PR 7.92683
237 2RDE C2E 7.92683
238 1VKF CIT 7.92683
239 6FA4 D1W 7.92683
240 5H2U 1N1 7.92683
241 5L2R MLA 7.92683
242 5MST FUM 7.92683
243 6BK3 B2S 7.92683
244 1ERB ETR 7.92683
245 3KYG 5GP 5GP 7.92683
246 4B1L FRU 7.92683
247 4O9S 2RY 7.92683
248 3T1A 5MA 7.92683
249 1TT8 PHB 7.92683
250 1HXD BTN 7.92683
251 6FIV 3TL 7.9646
252 1A78 TDG 8.20895
253 5TVF CGQ 8.23529
254 4NTK ZSP 8.26446
255 4NS0 PIO 8.27068
256 2YMZ LAT 8.46154
257 3JQ3 ADP 8.53659
258 5Y4R C2E 8.53659
259 5VNF VAL THR SER VAL VAL 8.53659
260 5H9Y BGC BGC BGC BGC 8.53659
261 5XLY C2E 8.53659
262 5TPV TYD 8.53659
263 6BHQ NAG NAG FUL BMA MAN MAN NAG GAL 8.53659
264 3GD8 GOL 8.53659
265 5XDT ZI7 8.53659
266 5NBP BGC BGC BGC 8.53659
267 4DXD 9PC 8.53659
268 4ITH RCM 8.53659
269 6A63 LAT 8.69565
270 5SVV FMN 8.75912
271 2P7Q GG6 9.02256
272 1I7M CG 9.14634
273 3DZ6 M8E 9.14634
274 4FFG 0U8 9.14634
275 1EWF PC1 9.14634
276 5TBM 79A 9.40171
277 3EFS BTN 9.44206
278 3WUD GLC GAL 9.55882
279 3PUN FUC GAL NDG FUC 9.7561
280 1DMY AZM 9.7561
281 1ZY5 ANP 9.7561
282 4ZTD ALA GLY ALA GLY ALA 9.7561
283 1YFS ALA 9.7561
284 3VKX T3 9.7561
285 2V0U FMN 10.274
286 2HZQ STR 10.3448
287 5GLT BGC GAL NAG GAL 10.3659
288 2WKQ FMN 10.3659
289 5W75 SUC 10.3659
290 3FW9 SLX 10.3659
291 4FE2 AIR 10.3659
292 1M15 ADP 10.3659
293 1M15 ARG 10.3659
294 1URX AAL GAL AAL GLA 10.3659
295 1NKI PPF 10.3704
296 4Y24 TD2 10.3896
297 4RT1 C2E 10.7143
298 2YPI PGA 10.9756
299 3WG3 A2G GAL NAG FUC 10.9756
300 1WW5 SGA BGC 11.25
301 5NFB 8VT 11.3636
302 4D5B ACX 11.5854
303 5EFW FMN 11.7241
304 5DJT FMN 11.7241
305 5DJU FMN 11.7241
306 3M3E GAL A2G NPO 11.8012
307 3UW4 MAA CHG PRO 0DQ 11.9565
308 3ZJX BOG 12.1951
309 6GG9 FMN 12.3457
310 3H0L ADP 12.766
311 5DYO FLU 12.8049
312 4YBN FAD 12.8049
313 3O61 GDD 12.8049
314 3I8T LBT 12.8049
315 4LOO SB4 12.8049
316 3AGC RCC 13.4146
317 2IPI AKY 13.4146
318 2R0H CTO 14.0244
319 1GP6 DH2 14.0244
320 1GP6 SIN 14.0244
321 1GP6 QUE 14.0244
322 1LSH PLD 14.6341
323 3QSB 743 14.6341
324 4Z3E GAL NGA GLA BGC GAL 14.6341
325 5W3Y ACO 14.6341
326 2GMH UQ5 14.6341
327 1VYF OLA 14.8148
328 5FPX GLY SER SER HIS HIS HIS HIS HIS 15.0442
329 5DKK FMN 15.1724
330 5LUN OGA 15.2439
331 4EES FMN 15.6522
332 4RD0 GDP 15.8537
333 2WT2 GAL NAG GAL NAG GAL NAG 15.8537
334 1ZB6 GST 15.8537
335 5FUI APY 15.9091
336 3E7S AT2 16.4634
337 1QKQ MAN 17.6056
338 4H2V AMP 18.1818
339 6FXR AKG 18.2927
340 2OO8 RAJ 18.2927
341 4IEN GDP 18.4049
342 2D6M LBT 18.8679
343 5O9W AKG 20.7317
344 5ACM MBT 21.6216
345 1KJ1 MAN 22.0183
346 3T50 FMN 22.6562
347 4B0T ADP 23.1707
Pocket No.: 2; Query (leader) PDB : 2AG4; Ligand: LP3; Similar sites found with APoc: 331
This union binding pocket(no: 2) in the query (biounit: 2ag4.bio2) has 57 residues
No: Leader PDB Ligand Sequence Similarity
1 3ZXE PGZ None
2 1MDC PLM None
3 4JH6 FCN None
4 5D48 L96 None
5 3CM2 X23 None
6 3G1Z AMP None
7 3OQJ 3CX None
8 2HO2 PRO PRO PRO PRO PRO PRO PRO PRO PRO LEU None
9 5F6U 5VK None
10 3HAV ATP None
11 2Z77 HE7 None
12 3QUG GIX None
13 1Y7P RIP None
14 5HZ9 5M8 None
15 3E85 BSU None
16 1LFO OLA None
17 2QM9 TDZ None
18 4BVM PLM None
19 4MOB ADP 1.21951
20 2E56 MYR 1.38889
21 2CJU PHX 1.65289
22 6EWZ APC 1.82927
23 2Z3U CRR 1.82927
24 1F5F DHT 1.82927
25 4WVW SLT 2.08333
26 5HZ5 65X 2.23881
27 1EWJ BLM 2.38095
28 4WCX MET 2.43902
29 5C5T AKG 2.43902
30 3AJH BL3 2.43902
31 6F5U CQN 2.43902
32 1EB1 ASP TYR GLU PRO ILE PRO GLU GLU ALA PHE 2.43902
33 2OBD 2OB 2.43902
34 3A16 PXO 2.43902
35 5H9Q TD2 2.58065
36 4R38 RBF 2.85714
37 5DG2 GAL GLC 2.96296
38 3OYW TDG 2.98507
39 3FW3 ETS 3.04878
40 3KYF 5GP 5GP 3.04878
41 5T8U LPA 3.04878
42 3T4L ZEA 3.04878
43 3PUR 2HG 3.04878
44 6D6L FY4 3.04878
45 2QHV OC9 3.04878
46 2YG2 FLC 3.04878
47 1O9U ADZ 3.04878
48 2QHS OCA 3.04878
49 1MJT ITU 3.04878
50 1RJW ETF 3.04878
51 2Z5Y HRM 3.04878
52 2YG2 S1P 3.04878
53 4HIA FMN 3.04878
54 4M1U A2G MBG 3.04878
55 5C3R HMU 3.04878
56 5C3R AKG 3.04878
57 2GJ5 VD3 3.08642
58 3SAO DBH 3.125
59 3SAO NKN 3.125
60 4K55 H6P 3.22581
61 1GU3 BGC BGC BGC BGC BGC 3.3557
62 4WUJ FMN 3.40136
63 3NV3 GAL NAG MAN 3.62319
64 5WHT SIA GAL GLC 3.62319
65 5KJW 53C 3.65854
66 2G30 ALA ALA PHE 3.65854
67 4XCB AKG 3.65854
68 2VFT SOR 3.65854
69 1ZNY GDP 3.65854
70 3RGA LSB 3.65854
71 6E1Q CFA 3.65854
72 4YVN EBS 3.65854
73 2OVD DAO 3.65854
74 4YGF AZM 3.65854
75 6GW4 CHO 3.65854
76 6GVZ CHO 3.65854
77 5OF1 SAL 3.65854
78 3R6K FUC GAL GLA 3.65854
79 5EJL C2E 3.65854
80 5JSP DQY 3.65854
81 1LNM DTX 3.65854
82 3CF6 SP1 3.65854
83 4ZSI 4R1 3.65854
84 5H5A 6OU 3.65854
85 5DQ8 FLF 3.65854
86 3V8S 0HD 3.65854
87 3CTL S6P 3.65854
88 5VL2 9EG 3.78788
89 1BHX ASP PHE GLU GLU ILE 3.80952
90 5T7I LAT NAG GAL 3.87097
91 3MTX PGT 3.97351
92 2AZ5 307 4.05405
93 1JIF CU BLM 4.09836
94 2VDF OCT 4.26829
95 2VL1 GLY GLY 4.26829
96 3JU6 ANP 4.26829
97 5YJS SAL 4.26829
98 4XMF HSM 4.26829
99 5D9G GLU ASN LEU TYR PHE GLN 4.26829
100 4ORR PE3 4.26829
101 4IMO PWZ 4.26829
102 1X8X TYR 4.26829
103 3TTZ 07N 4.26829
104 3W68 VIV 4.26829
105 5T96 79J 4.26829
106 5HV7 RBL 4.26829
107 5LRT ADP 4.26829
108 5F7J ADE 4.26829
109 3A5Z KAA 4.26829
110 3A5Y KAA 4.26829
111 1UNB AKG 4.26829
112 4V15 PLP 4.26829
113 5VAD PRO 4.26829
114 1UNB PN1 4.26829
115 3SLS 77D 4.26829
116 5FP4 YC8 4.26829
117 1C1L GAL BGC 4.37956
118 1IS3 LAT 4.44444
119 5CJ3 52G 4.44444
120 5BVT PAM 4.47761
121 2HKA C3S 4.61538
122 1ULE GLA GAL NAG 4.66667
123 5VM0 9EG 4.6875
124 4BG4 ADP 4.87805
125 3WV6 GAL BGC 4.87805
126 4D4U FUC NDG GAL FUC 4.87805
127 5JJU AMP 4.87805
128 2ET1 GLV 4.87805
129 1W2D ADP 4.87805
130 3WV6 GAL GLC 4.87805
131 3ZGJ RMN 4.87805
132 5TZO 7V7 4.87805
133 4NG2 OHN 4.87805
134 3E2M E2M 4.87805
135 1W96 S1A 4.87805
136 3QP8 HL0 4.87805
137 5J75 6GQ 4.87805
138 4D52 GIV 4.87805
139 4D4U FUC GAL NDG FUC 4.87805
140 3LVW GSH 4.87805
141 1KZN CBN 4.87805
142 1KDK DHT 4.87805
143 1I0B PEL 4.87805
144 3ACL 3F1 4.87805
145 5H9P TD2 5.06329
146 6GNO XDI 5.18518
147 1OPB RET 5.22388
148 4QYN RTL 5.26316
149 5HWV MBN 5.38462
150 2ZHL NAG GAL GAL NAG 5.40541
151 2Z6C FMN 5.42636
152 4RF7 ARG 5.4878
153 1SDW IYT 5.4878
154 1ELI PYC 5.4878
155 4NPL AKG 5.4878
156 4WOE ADP 5.4878
157 3P7N FMN 5.4878
158 1J3R 6PG 5.4878
159 4YRI 4JH 5.4878
160 5INJ 6C7 5.4878
161 2GQS C2R 5.4878
162 2Y3S TIR 5.4878
163 5F7N NAG GAL FUC FUC A2G 5.4878
164 3CBC DBS 5.55556
165 2BS5 BGC GAL FUC 5.55556
166 5VGS 9A7 5.73248
167 5VGS 9A4 5.73248
168 5ODY 9SK 5.7971
169 4RYV ZEA 5.80645
170 1SLT NDG GAL 5.97015
171 4IAW LIZ 6.09756
172 4KBA 1QM 6.09756
173 5G48 1FL 6.09756
174 2XG5 EC2 6.09756
175 2XG5 EC5 6.09756
176 1U6R ADP 6.09756
177 1GQG DCD 6.09756
178 1QY1 PRZ 6.09756
179 2GC0 PAN 6.09756
180 4H2W AMP 6.09756
181 5FLJ QUE 6.09756
182 6FOF LAT 6.09756
183 3MF2 AMP 6.09756
184 4H2X G5A 6.09756
185 6BU0 IHP 6.10687
186 3FW4 CAQ 6.17978
187 3VV1 GAL FUC 6.25
188 4TW7 37K 6.25
189 1KGI T4A 6.29921
190 4RLT FSE 6.32911
191 3QRC SCR 6.36943
192 1N9L FMN 6.42202
193 4YLZ LAT NAG GAL 6.53595
194 4L4J NAG NAG BMA MAN NAG 6.70732
195 5EO8 TFU 6.70732
196 2OJW ADP 6.70732
197 4MVK ACE VAL PHE PHE ALA GLU ASP NH2 6.70732
198 6CC0 EWM 6.70732
199 5Y72 DST 6.70732
200 2YKL NLD 6.70732
201 5NKN LOC 6.70732
202 4CQE CQE 6.70732
203 2NSX IFM 6.70732
204 6E08 NAP 6.70732
205 4HWT 1B2 6.70732
206 4ZU4 4TG 6.75676
207 2GTF P1R 7.31707
208 1VRP ADP 7.31707
209 3GD9 GLC BGC BGC BGC 7.31707
210 5X7Q GLC GLC GLC GLC GLC 7.31707
211 5X7Q GLC GLC GLC GLC 7.31707
212 2J3M ATP 7.31707
213 2J3M PRI 7.31707
214 6CAY ERG 7.31707
215 2RHQ GAX 7.31707
216 5OX6 A1Z 7.31707
217 3IWD M2T 7.35294
218 5M6N 7H9 7.62712
219 4WN5 MVC 7.82609
220 5OCG 9R5 7.92683
221 1F9V ADP 7.92683
222 3B6R ADP 7.92683
223 4L9I 8PR 7.92683
224 2RDE C2E 7.92683
225 1VKF CIT 7.92683
226 5H2U 1N1 7.92683
227 5L2R MLA 7.92683
228 6FA4 D1W 7.92683
229 5MST FUM 7.92683
230 1GPM AMP 7.92683
231 6BK3 B2S 7.92683
232 1ERB ETR 7.92683
233 3KYG 5GP 5GP 7.92683
234 4B1L FRU 7.92683
235 4O9S 2RY 7.92683
236 1TT8 PHB 7.92683
237 3T1A 5MA 7.92683
238 1HXD BTN 7.92683
239 6FIV 3TL 7.9646
240 1A78 TDG 8.20895
241 5TVF CGQ 8.23529
242 4NTK ZSP 8.26446
243 2YMZ LAT 8.46154
244 6BHQ NAG NAG FUL BMA MAN MAN NAG GAL 8.53659
245 3JQ3 ADP 8.53659
246 5Y4R C2E 8.53659
247 5VNF VAL THR SER VAL VAL 8.53659
248 5H9Y BGC BGC BGC BGC 8.53659
249 5XLY C2E 8.53659
250 5XDT ZI7 8.53659
251 5TPV TYD 8.53659
252 4DXD 9PC 8.53659
253 3GD8 GOL 8.53659
254 6A63 LAT 8.69565
255 5SVV FMN 8.75912
256 2P7Q GG6 9.02256
257 1I7M CG 9.14634
258 3DZ6 M8E 9.14634
259 4FFG 0U8 9.14634
260 1EWF PC1 9.14634
261 5NLD LBT 9.35252
262 3EFS BTN 9.44206
263 3WUD GLC GAL 9.55882
264 4GLW 0XT 9.7561
265 1YFS ALA 9.7561
266 1DMY AZM 9.7561
267 1ZY5 ANP 9.7561
268 3VKX T3 9.7561
269 2V0U FMN 10.274
270 2HZQ STR 10.3448
271 5GLT BGC GAL NAG GAL 10.3659
272 2WKQ FMN 10.3659
273 5W75 SUC 10.3659
274 4FE2 AIR 10.3659
275 3FW9 SLX 10.3659
276 1M15 ARG 10.3659
277 1M15 ADP 10.3659
278 1NKI PPF 10.3704
279 4Y24 TD2 10.3896
280 4RT1 C2E 10.7143
281 3WG3 A2G GAL NAG FUC 10.9756
282 2YPI PGA 10.9756
283 1WW5 SGA BGC 11.25
284 5NFB 8VT 11.3636
285 5W7B MYR 11.5854
286 4D5B ACX 11.5854
287 5EFW FMN 11.7241
288 5DJT FMN 11.7241
289 5DJU FMN 11.7241
290 3M3E GAL A2G NPO 11.8012
291 3ZJX BOG 12.1951
292 6GG9 FMN 12.3457
293 2QL9 CIT 12.3711
294 3H0L ADP 12.766
295 5DYO FLU 12.8049
296 4YBN FAD 12.8049
297 3O61 GDD 12.8049
298 3I8T LBT 12.8049
299 4LOO SB4 12.8049
300 2R0H CTO 14.0244
301 1GP6 SIN 14.0244
302 1GP6 DH2 14.0244
303 1GP6 QUE 14.0244
304 2YAK OSV 14.0244
305 1LSH PLD 14.6341
306 3QSB 743 14.6341
307 5W3Y ACO 14.6341
308 2GMH UQ5 14.6341
309 4Z3E GAL NGA GLA BGC GAL 14.6341
310 1VYF OLA 14.8148
311 5FPX GLY SER SER HIS HIS HIS HIS HIS 15.0442
312 5DKK FMN 15.1724
313 5LUN OGA 15.2439
314 4EES FMN 15.6522
315 4RD0 GDP 15.8537
316 2WT2 GAL NAG GAL NAG GAL NAG 15.8537
317 1ZB6 GST 15.8537
318 5FUI APY 15.9091
319 3E7S AT2 16.4634
320 1QKQ MAN 17.6056
321 4H2V AMP 18.1818
322 2OO8 RAJ 18.2927
323 4IEN GDP 18.4049
324 6E2B PT7 18.4211
325 2D6M LBT 18.8679
326 5O9W AKG 20.7317
327 5ACM MBT 21.6216
328 2VWA PTY 21.7822
329 1KJ1 MAN 22.0183
330 3T50 FMN 22.6562
331 4B0T ADP 23.1707
Pocket No.: 3; Query (leader) PDB : 2AG4; Ligand: OLA; Similar sites found with APoc: 79
This union binding pocket(no: 3) in the query (biounit: 2ag4.bio1) has 60 residues
No: Leader PDB Ligand Sequence Similarity
1 1UYY BGC BGC None
2 2VSL MAA LYS PRO PHE None
3 1SW0 PGA None
4 2QM9 TDZ None
5 2Z77 HE7 None
6 3QH2 3NM 1.82927
7 3JQQ FAD 1.89873
8 3IWJ NAD 2.43902
9 6G9I CXX 2.43902
10 2JLD AG1 2.43902
11 4I9B NAD 2.43902
12 1N5S ADL 2.67857
13 4H69 10Y 3.04878
14 4CS4 ANP 3.04878
15 1ZM1 BGC BGC BGC 3.04878
16 3TAY MN0 3.06748
17 2Z6D FMN 3.07692
18 1SU2 ATP 3.14465
19 6CZI 38E 3.57143
20 5VM6 9EG 3.64964
21 2IF8 ADP 3.65854
22 2FCU AKG 3.65854
23 5HV0 AKG 3.65854
24 1EX7 5GP 3.65854
25 5DQ8 FLF 3.65854
26 5JSP DQY 3.65854
27 2Q8E OGA 3.65854
28 1IIU RTL 3.65854
29 3E9I XAH 3.65854
30 2JIG PD2 4.26829
31 5V59 8X1 4.26829
32 5DMZ ADP 4.26829
33 3B00 16A 4.26829
34 5E2N V14 4.26829
35 4QAC KK3 4.87805
36 3M3R BCD 4.87805
37 4X9X OLA 4.87805
38 5LJB RTL 5.18518
39 5ISY NAD 5.4878
40 4WW8 VD9 5.4878
41 3VRY B43 5.4878
42 5N2D 8J8 5.55556
43 1TW4 CHD 5.6
44 2R5V HHH 6.09756
45 4H2W 5GP 6.09756
46 1OGX EQU 6.10687
47 4UA7 3GK 6.70732
48 6GR0 F8W 6.70732
49 4UAA 3GK 6.70732
50 4DDY DN6 6.70732
51 4HY1 19X 6.70732
52 5MW8 ATP 6.70732
53 3THR C2F 7.31707
54 5OX6 A1Z 7.31707
55 4UYW H1S 7.92683
56 1ODM ASV 7.92683
57 3N0Y APC 7.92683
58 1JJE BYS 7.92683
59 1Q11 TYE 8.53659
60 1F52 ADP 9.14634
61 3HXU A5A 9.14634
62 5FQK 6NT 9.29368
63 5NLD LBT 9.35252
64 4NV7 COA 9.7561
65 2CM4 RCL 10
66 2PNC CLU 10.9756
67 5W7B MYR 11.5854
68 1W6P NDG GAL 11.9403
69 1OFL NGK GCD 12.1951
70 2RC5 FAD 12.1951
71 2QL9 CIT 12.3711
72 5XQW 8EU 12.8049
73 5XK9 DMA 12.8049
74 3PQB VGP 14.0244
75 4NOS ITU 14.6341
76 1ZB6 DIN 15.8537
77 6E2B PT7 18.4211
78 2WNF CG3 A2G GAL 20.7317
79 3PVW QRX 32.4324
Pocket No.: 4; Query (leader) PDB : 2AG4; Ligand: LP3; Similar sites found with APoc: 87
This union binding pocket(no: 4) in the query (biounit: 2ag4.bio1) has 60 residues
No: Leader PDB Ligand Sequence Similarity
1 1UYY BGC BGC None
2 5OQW A4E None
3 2VSL MAA LYS PRO PHE None
4 1SW0 PGA None
5 3QH2 3NM 1.82927
6 3JQQ FAD 1.89873
7 3ZW2 NAG GAL FUC 2.29885
8 3IWJ NAD 2.43902
9 6G9I CXX 2.43902
10 2JLD AG1 2.43902
11 1N5S ADL 2.67857
12 4H69 10Y 3.04878
13 1SQI 869 3.04878
14 4CS4 ANP 3.04878
15 1ZM1 BGC BGC BGC 3.04878
16 3TAY MN0 3.06748
17 2Z6D FMN 3.07692
18 1SU2 ATP 3.14465
19 6CZI 38E 3.57143
20 5VM6 9EG 3.64964
21 2IF8 ADP 3.65854
22 2FCU AKG 3.65854
23 5HV0 AKG 3.65854
24 1EX7 5GP 3.65854
25 2Q8E OGA 3.65854
26 1IIU RTL 3.65854
27 2JIG PD2 4.26829
28 4EE7 PIS 4.26829
29 5V59 8X1 4.26829
30 5DMZ ADP 4.26829
31 3B00 16A 4.26829
32 5E2N V14 4.26829
33 5B09 4MX 4.80769
34 2WA4 069 4.87805
35 4YZ5 SLT 4.87805
36 4QAC KK3 4.87805
37 4MZU TYD 4.87805
38 4X9X OLA 4.87805
39 5OMY 9YE 4.87805
40 1W2D 4IP 4.87805
41 3M3R BCD 4.87805
42 5LJB RTL 5.18518
43 4OCT AKG 5.4878
44 1ZGS XMM 5.4878
45 5ISY NAD 5.4878
46 5F7Y GLC GAL NAG GAL FUC A2G 5.4878
47 4WW8 VD9 5.4878
48 1TW4 CHD 5.6
49 2R5V HHH 6.09756
50 4H2W 5GP 6.09756
51 1OGX EQU 6.10687
52 5FPE 3TR 6.70732
53 4UA7 3GK 6.70732
54 6GR0 F8W 6.70732
55 4UAA 3GK 6.70732
56 6FE1 V14 6.70732
57 4DDY DN6 6.70732
58 4HY1 19X 6.70732
59 5MW8 ATP 6.70732
60 5KEW 6SB 6.94444
61 3THR C2F 7.31707
62 5XEG AKG 7.31707
63 6AC9 ANP 7.31707
64 4UYW H1S 7.92683
65 1ODM ASV 7.92683
66 3N0Y APC 7.92683
67 1JJE BYS 7.92683
68 1Q11 TYE 8.53659
69 5NBP BGC BGC BGC 8.53659
70 4ITH RCM 8.53659
71 1F52 ADP 9.14634
72 4ZTD ALA GLY ALA GLY ALA 9.7561
73 4NV7 COA 9.7561
74 2PNC CLU 10.9756
75 1W6P NDG GAL 11.9403
76 1OFL NGK GCD 12.1951
77 2Y2B AH0 12.1951
78 2RC5 FAD 12.1951
79 5XQW 8EU 12.8049
80 5XK9 DMA 12.8049
81 3AGC RCC 13.4146
82 2IPI AKY 13.4146
83 4NOS ITU 14.6341
84 4P42 PEE 15.2439
85 1ZB6 DIN 15.8537
86 2WNF CG3 A2G GAL 20.7317
87 3PVW QRX 32.4324
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