Receptor
PDB id Resolution Class Description Source Keywords
2B8W 2.22 Å EC: 3.-.-.- CRYSTAL-STRUCTURE OF THE N-TERMINAL LARGE GTPASE DOMAIN OF H GUANYLATE BINDING PROTEIN 1 (HGBP1) IN COMPLEX WITH GMP/ALF HOMO SAPIENS PROTEIN- GUANINE NUCLEOTIDE COMPLEX SIGNALING PROTEIN
Ref.: HOW GUANYLATE-BINDING PROTEINS ACHIEVE ASSEMBLY-STI PROCESSIVE CLEAVAGE OF GTP TO GMP. NATURE V. 440 101 2006
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ALF 5GP A:594;
B:594;
Valid;
Valid;
none;
none;
submit data
464.181 n/a [P+](...
MG A:595;
B:595;
Part of Protein;
Part of Protein;
none;
none;
submit data
24.305 Mg [Mg+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2B8W 2.22 Å EC: 3.-.-.- CRYSTAL-STRUCTURE OF THE N-TERMINAL LARGE GTPASE DOMAIN OF H GUANYLATE BINDING PROTEIN 1 (HGBP1) IN COMPLEX WITH GMP/ALF HOMO SAPIENS PROTEIN- GUANINE NUCLEOTIDE COMPLEX SIGNALING PROTEIN
Ref.: HOW GUANYLATE-BINDING PROTEINS ACHIEVE ASSEMBLY-STI PROCESSIVE CLEAVAGE OF GTP TO GMP. NATURE V. 440 101 2006
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 218 families.
1 2B8W - ALF 5GP n/a n/a
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 176 families.
1 2B8W - ALF 5GP n/a n/a
50% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 171 families.
1 1F5N - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
2 2B8W - ALF 5GP n/a n/a
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ALF 5GP; Similar ligands found: 112
No: Ligand ECFP6 Tc MDL keys Tc
1 ALF 5GP 1 1
2 GDP ALF 0.857143 1
3 GDP MG 0.795181 0.91358
4 GDP BEF 0.785714 0.938272
5 BEF GDP 0.77907 0.950617
6 GDP AF3 0.772727 1
7 GTP MG 0.758621 0.91358
8 5GP 0.753086 0.9
9 G 0.753086 0.9
10 GDP 0.729412 0.888889
11 GP3 0.717647 0.86747
12 G G 0.709677 0.901235
13 GP2 0.709302 0.857143
14 GNH 0.701149 0.878049
15 GCP 0.696629 0.86747
16 GCP G 0.692308 0.901235
17 G2P 0.688889 0.857143
18 GTP 0.685393 0.888889
19 GMV 0.685393 0.890244
20 G1R 0.677778 0.878049
21 GSP 0.67033 0.847059
22 GNP 0.67033 0.86747
23 GDP 7MG 0.666667 0.879518
24 GAV 0.655914 0.857143
25 GMP 0.6375 0.802469
26 G2R 0.635417 0.857143
27 GPG 0.628866 0.857143
28 YGP 0.61 0.827586
29 G3A 0.607843 0.86747
30 6CK 0.607843 0.903614
31 GDD 0.60396 0.857143
32 GKE 0.60396 0.857143
33 Y9Z 0.60396 0.808989
34 GDC 0.60396 0.857143
35 U A G G 0.603604 0.901235
36 G5P 0.601942 0.86747
37 GTG 0.598039 0.858824
38 GFB 0.598039 0.857143
39 GDR 0.598039 0.857143
40 G A A A 0.594595 0.890244
41 I2C FE2 CMO CMO 0.59292 0.804348
42 JB2 0.580952 0.857143
43 GKD 0.580952 0.857143
44 GPD 0.575472 0.827586
45 GDX 0.575472 0.86747
46 3GP 0.573034 0.864198
47 G3D 0.56701 0.876543
48 G4P 0.555556 0.876543
49 G1R G1R 0.554622 0.869048
50 PGD O 0.55 0.784946
51 JB3 0.54955 0.847059
52 FEG 0.544643 0.808989
53 NGD 0.544643 0.879518
54 U2G 0.544643 0.837209
55 ZGP 0.539823 0.8
56 G G U 0.537037 0.878049
57 CG2 0.535088 0.837209
58 0O2 0.533981 0.876543
59 2MD 0.530435 0.8
60 G C 0.530435 0.869048
61 CAG 0.529915 0.811111
62 2GP 0.521739 0.853659
63 MGD 0.516949 0.8
64 FE9 0.516667 0.755102
65 MD1 0.512397 0.8
66 DBG 0.504065 0.847059
67 U G A 0.503817 0.858824
68 PGD 0.5 0.827586
69 TPG 0.491935 0.757895
70 G G G C 0.491803 0.858824
71 G G G RPC 0.491525 0.845238
72 GPX 0.490385 0.841463
73 A G C C 0.487805 0.879518
74 APC G U 0.487603 0.855422
75 DGI 0.484848 0.823529
76 DGP 0.484211 0.833333
77 DG 0.484211 0.833333
78 P2G 0.479167 0.807229
79 DG DG 0.476636 0.837209
80 ADP ALF 0.475248 0.9125
81 ALF ADP 0.475248 0.9125
82 G C C C 0.472441 0.869048
83 GH3 0.471154 0.865854
84 P1G 0.469388 0.797619
85 G4M 0.466165 0.791209
86 BGO 0.466102 0.825581
87 DGT 0.466019 0.823529
88 A G U 0.462687 0.858824
89 IMP 0.458333 0.875
90 IDP 0.45 0.864198
91 GGM 0.442623 0.806818
92 5GP 5GP 0.441176 0.851852
93 G7M 0.438776 0.890244
94 G U34 0.438017 0.858824
95 SGP 0.434343 0.758621
96 GPC 0.432 0.872093
97 C2E 0.431373 0.841463
98 PCG 0.431373 0.851852
99 35G 0.431373 0.851852
100 G1G 0.425197 0.848837
101 ADP MG 0.42 0.829268
102 ADP BEF 0.415842 0.853659
103 BEF ADP 0.415842 0.853659
104 OMC OMU OMG OMG U 0.414286 0.83908
105 DC DG 0.408 0.818182
106 ADP PO3 0.407767 0.8375
107 MGP 0.40566 0.879518
108 ATP MG 0.403846 0.829268
109 3PD UM3 0.403226 0.816092
110 AMP MG 0.402062 0.817073
111 6G0 0.401869 0.879518
112 GAP 0.4 0.819277
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2B8W; Ligand: ALF 5GP; Similar sites found: 452
This union binding pocket(no: 1) in the query (biounit: 2b8w.bio1) has 25 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1EK0 GNP 0.000004788 0.5142 None
2 3TK1 GDP 0.00008319 0.53551 1.21951
3 3BFX A3P 0.001122 0.44212 1.35135
4 3BFV ADP 0.001395 0.46087 1.47601
5 4BAS GNP 0.000002598 0.52079 1.50754
6 1SVK ALF GDP 0.000009667 0.52115 1.52439
7 1AZT GSP 0.000006738 0.48518 1.52439
8 1Y3A GDP 0.001102 0.43094 1.52439
9 4XGU ADP 0.003247 0.42559 1.52439
10 2OM2 GDP 0.001574 0.43178 1.53846
11 1BH2 GSP 0.00000751 0.48374 1.5873
12 1SQ5 ADP 0.000277 0.48948 1.62338
13 1P4V GLY 0.0108 0.42796 1.69492
14 2DPY ADP 0.0004057 0.49989 1.82927
15 2C9O ADP 0.0005148 0.45268 1.82927
16 5M7P ADP 0.001898 0.43209 1.82927
17 2ZPT A3P 0.01107 0.41525 2.0339
18 4D81 ADP 0.00114 0.45041 2.12014
19 3LRE ADP 0.00005053 0.55582 2.13415
20 5M04 GDP 0.0001173 0.52054 2.13415
21 4J0Q GDP 0.0001887 0.51012 2.13415
22 3DZD ADP 0.0004841 0.46748 2.13415
23 5KDO GDP 0.0008171 0.44404 2.13415
24 5EE7 5MV 0.009632 0.42713 2.13415
25 5WRI A3P 0.002183 0.42209 2.1875
26 4WOP CTP 0.0006617 0.44798 2.22222
27 3E5H GNP 0.0001364 0.45776 2.24719
28 3NHB ADP 0.0002208 0.51868 2.28758
29 5L3W GDP 0.001607 0.44806 2.28758
30 5WRJ A3P 0.003144 0.40896 2.31023
31 5X40 ACP 0.0004853 0.43745 2.39726
32 5GJC ATP 0.0003104 0.49297 2.43902
33 5GOE GDP 0.0002876 0.48312 2.43902
34 4HSE ADP 0.000441 0.47978 2.43902
35 3RC3 ANP 0.005363 0.43677 2.43902
36 1W5T ANP 0.002588 0.42249 2.43902
37 1W5T ADP 0.00447 0.41935 2.43902
38 2Q2Y MKR 0.007884 0.40939 2.43902
39 2Q2Y ADP 0.008504 0.409 2.43902
40 3BOS CDP 0.00002687 0.54523 2.47934
41 2ZFI ADP 0.0003121 0.49286 2.73224
42 4PPF FLC 0.000008033 0.59833 2.7439
43 1WDT GTP 0.00001242 0.52802 2.7439
44 3WYA GDP 0.0004547 0.48482 2.7439
45 1G7S GDP 0.0008735 0.46552 2.7439
46 2FAH GDP 0.0006319 0.46217 2.7439
47 4PFO ADP 0.0006033 0.43986 2.7439
48 5I34 GDP 0.003088 0.43917 2.7439
49 2ZTS ADP 0.003279 0.42164 2.7439
50 2ZE7 DST 0.005358 0.40268 2.7668
51 2ZE7 AMP 0.004979 0.40245 2.7668
52 1FP6 ADP 0.0009295 0.45448 2.76817
53 4TTQ ATP 0.00007524 0.52324 2.7907
54 1NJF AGS 0.001636 0.41162 2.8
55 1NJF ADP 0.00109 0.40761 2.8
56 5J1J ANP 0.001102 0.43095 2.80702
57 3MGB PAP 0.002269 0.42495 2.82132
58 2ODE ALF GDP 0.000008442 0.48173 2.83688
59 4LPS GDP 0.0008937 0.46505 2.89256
60 1JJV ATP 0.00008388 0.54073 2.91262
61 1Z08 GNP 0.0003629 0.4509 2.94118
62 5UWT GNP 0.000005455 0.52538 2.95359
63 5DHF GNP 0.000004858 0.50561 2.95359
64 5UWH GNP 0.000005199 0.50449 2.95359
65 5DIF GNP 0.000005185 0.50446 2.95359
66 5UWI GNP 0.000005304 0.50407 2.95359
67 5UWR GNP 0.000005556 0.5034 2.95359
68 5UWJ GNP 0.000005646 0.50311 2.95359
69 5UWU GNP 0.000005846 0.50266 2.95359
70 5UWW GNP 0.000006212 0.50166 2.95359
71 5UWQ GNP 0.000006996 0.49974 2.95359
72 5UWO GNP 0.000007139 0.49938 2.95359
73 5DI9 GNP 0.000006075 0.49405 2.95359
74 5UWP GNP 0.000006183 0.49375 2.95359
75 5UWS GNP 0.000007481 0.49094 2.95359
76 2IS6 ADP 0.0001072 0.51568 3.04878
77 3CX8 GSP 0.000007902 0.48264 3.04878
78 5BQ5 ADP BEF 0.0009096 0.45966 3.04878
79 3FKQ ATP 0.0007134 0.45514 3.04878
80 5XDR ADP 0.002037 0.44786 3.04878
81 3EZ2 ADP 0.006324 0.43315 3.04878
82 4YS0 ADP 0.005935 0.41381 3.04878
83 4V03 ADP 0.00281 0.43666 3.11284
84 2ZPA ADP 0.00148 0.40135 3.12966
85 4HAT GNP 0.000005508 0.52731 3.24074
86 4DKX GDP 0.0002383 0.49862 3.24074
87 3FB4 AP5 0.003907 0.4236 3.24074
88 4WEI GLC GAL 0.002618 0.45932 3.2491
89 2EFE GNH 0.002365 0.43587 3.31492
90 2AWN ADP 0.00002218 0.5794 3.35366
91 5TSH ADP 0.00006417 0.54715 3.35366
92 2BVN GNP 0.00002046 0.53049 3.35366
93 5TSH ANP 0.000117 0.51381 3.35366
94 3U6B GDP 0.0001596 0.51379 3.35366
95 5JBQ GDP 0.000227 0.49966 3.35366
96 4G5G GDP 0.0003216 0.49221 3.35366
97 3U6K GDP 0.0004603 0.48456 3.35366
98 4PC3 GDP 0.002228 0.43706 3.35366
99 3QKT ANP 0.002394 0.41376 3.35366
100 1P9B GDP 0.006161 0.41309 3.35366
101 2CJP VPR 0.02335 0.40964 3.35366
102 1G41 ADP 0.001133 0.45519 3.37838
103 1KO8 6PG 0.0003128 0.42727 3.42857
104 1YRB GDP 0.0004544 0.46874 3.43511
105 2QZ4 ADP 0.0006351 0.46698 3.43511
106 4WZ6 ATP 0.0002216 0.5186 3.44828
107 3KA2 2NC 0.01828 0.40318 3.44828
108 5K5Z ANP 0.0009252 0.43051 3.50318
109 4YDS ATP 0.0001628 0.52041 3.50877
110 5E5U MLI 0.008625 0.44375 3.51759
111 3T1O GDP 0.0003043 0.41135 3.53535
112 1CS4 GSP 0.000004638 0.49825 3.55556
113 3QH2 3NM 0.02701 0.4052 3.61991
114 4ZNL BEF ADP 0.0002078 0.49547 3.64964
115 2C78 GNP 0.000006006 0.53006 3.65854
116 2XTZ GSP 0.000009722 0.51296 3.65854
117 2C77 GNP 0.000004287 0.50406 3.65854
118 1KK1 GNP 0.0003064 0.49951 3.65854
119 5KSZ GCP 0.0003048 0.48193 3.65854
120 1Z6T ADP 0.0003203 0.47075 3.65854
121 4OHY ANP 0.0002292 0.45509 3.65854
122 2HS3 FGR 0.005358 0.41226 3.65854
123 4A9C B5F 0.04124 0.40031 3.79747
124 2PL3 ADP 0.000273 0.50204 3.81356
125 2VOH CIT 0.0278 0.41571 3.82166
126 1L2T ATP 0.001698 0.41982 3.82979
127 2GK6 ADP 0.005251 0.44227 3.84615
128 2BCG GDP 0.001027 0.44381 3.8835
129 2Y8E GNP 0.000003402 0.52004 3.91061
130 1RYH GNP 0.000008731 0.46238 3.94089
131 4NCN GTP 0.000001126 0.55458 3.96341
132 4TMZ GSP 0.000001371 0.55105 3.96341
133 5GVR LMR 0.0003187 0.52245 3.96341
134 2BIF SIN 0.0004497 0.46759 3.96341
135 2BIF ANP 0.0002422 0.46759 3.96341
136 1K6M AGS 0.0001449 0.46738 3.96341
137 5LTJ ADP 0.0009891 0.46293 3.96341
138 2CK3 ANP 0.0007836 0.44897 3.96341
139 2CK3 ADP 0.0007395 0.43811 3.96341
140 5LTJ BEF 0.01257 0.42831 3.96341
141 1W0J ADP 0.0002556 0.41627 3.96341
142 1W0J ADP BEF 0.0008046 0.4153 3.96341
143 4QDI ATP 0.01918 0.40093 3.96341
144 2GWH A3P 0.001145 0.44591 4.02685
145 2OZE AGS 0.000475 0.42283 4.02685
146 2FFQ GSP 0.000004681 0.5281 4.09357
147 1YZQ GNP 0.000004061 0.50841 4.11765
148 2OG2 MLI 0.0002392 0.51103 4.17827
149 5HCN GCP 0.0001063 0.50945 4.21456
150 2X7I CIT 0.007487 0.42491 4.22078
151 2NCD ADP 0.00009148 0.53715 4.26829
152 2QN6 GDP 0.00006064 0.53498 4.26829
153 4RD0 GDP 0.000005472 0.53176 4.26829
154 3T34 GDP 0.00006875 0.48077 4.26829
155 4P4T GDP 0.00103 0.44375 4.26829
156 1MKY GDP 0.0001906 0.40168 4.26829
157 1D5C GDP 0.0003165 0.47098 4.32099
158 4GBM A3P 0.001875 0.42141 4.33437
159 2C04 GCP 0.003789 0.42258 4.3771
160 1GXU 2HP 0.00006849 0.57391 4.3956
161 3W5J GDP 0.0000002218 0.68612 4.41176
162 3FWY ADP 0.001072 0.40289 4.4586
163 4GOX A3P 0.0004177 0.44837 4.47284
164 5G41 AP5 0.00625 0.41966 4.4843
165 2ZR9 DTP 0.0001559 0.50769 4.57317
166 5I0H ADP BEF 0.0000129 0.48719 4.57317
167 2OBM ADP 0.001264 0.48503 4.57317
168 4Y4V DAL 0.00268 0.45861 4.57317
169 1IN4 ADP 0.001186 0.44106 4.57317
170 3TMK T5A 0.001196 0.40159 4.62963
171 3DC4 ADP 0.00003428 0.55543 4.65116
172 1U8Z GDP 0.0005457 0.44357 4.7619
173 1T8U UAP SGN IDS SGN 0.008857 0.40823 4.77941
174 2OFW ADX 0.009469 0.40596 4.80769
175 3BER AMP 0.007165 0.42586 4.81928
176 3Q72 GNP 0.00009029 0.40284 4.81928
177 1U0J ADP 0.000241 0.50477 4.86891
178 5IRR GSP 0.000007403 0.52623 4.87013
179 5HR5 ADP 0.00004602 0.50855 4.87805
180 2FNA ADP 0.000425 0.45207 4.87805
181 4H1V GNP 0.003797 0.42254 4.87805
182 5SZH GNP 0.000006703 0.52171 4.92611
183 2A9K GDP 0.001116 0.40201 4.93274
184 5MVR ADP 0.00109 0.46614 4.93827
185 3ZQ6 ADP ALF 0.0004055 0.44868 4.93827
186 2XT3 ADP 0.00003989 0.5586 4.94186
187 3B9Q MLI 0.0009033 0.47868 4.96689
188 2EW1 GNP 0.000002006 0.53157 4.97512
189 1UAD GNP 0.00000884 0.51464 5.05051
190 1G6H ADP 0.00002546 0.5742 5.05837
191 3RLF ANP 0.001281 0.42825 5.06757
192 1XTQ GDP 0.0000613 0.47302 5.08475
193 3TKL GTP 0.000003399 0.52924 5.10204
194 4HI0 GDP 0.001146 0.43773 5.11811
195 1B7T ADP 0.0001805 0.49261 5.12821
196 4PX9 ADP 0.0003413 0.49715 5.13699
197 2FH5 GTP 0.00001067 0.52509 5.14019
198 1D2N ANP 0.0005257 0.45228 5.14706
199 1M2O GNP 0.000005504 0.52303 5.18293
200 4DCT GDP 0.0001469 0.5027 5.18293
201 4WZA ADP 0.0002103 0.49688 5.18293
202 4WZA ACP 0.0002103 0.49688 5.18293
203 5IRN ADP 0.0002031 0.48478 5.18293
204 1D2E GDP 0.0005159 0.46621 5.18293
205 3ZFD ANP 0.00001092 0.46392 5.18293
206 1YTM ATP 0.0008105 0.44419 5.18293
207 1KK8 BEF ADP 0.0002739 0.47379 5.19481
208 1ZCB GDP 0.0004034 0.44699 5.24862
209 3AB3 GDP 0.0005723 0.42291 5.24862
210 1Z06 GNP 0.00000665 0.51743 5.29101
211 4DSU GDP 0.0001855 0.44538 5.29101
212 5UQW GDP 0.0003992 0.44532 5.29101
213 1G16 GDP 0.0004512 0.43283 5.29412
214 2HF9 GSP 0.0002939 0.47243 5.30973
215 1YVD GNP 0.000007078 0.50739 5.32544
216 3Q85 GNP 0.0001852 0.40132 5.32544
217 2Z5F A3P 0.0007325 0.44608 5.36913
218 1YZN GNP 0.000004889 0.50499 5.40541
219 1JI0 ATP 0.0000444 0.54962 5.41667
220 2CBZ ATP 0.000008842 0.59792 5.48523
221 1GOJ ADP 0.00003209 0.568 5.4878
222 2WHX ADP 0.0003034 0.51142 5.4878
223 5FTB ANP 0.000329 0.48038 5.4878
224 4LYA ATP 0.001315 0.45699 5.4878
225 5FHD ADP ALF 0.0005289 0.45217 5.4878
226 3FVQ ATP 0.001099 0.4385 5.4878
227 2JLR ANP 0.000847 0.40051 5.4878
228 3SFV GDP 0.001596 0.40682 5.52486
229 5L3R GCP 0.00007091 0.47575 5.64784
230 3NKV GNP 0.000007661 0.5062 5.71429
231 3DKP ADP 0.0003207 0.49228 5.71429
232 2CJW GDP 0.0003414 0.49094 5.72917
233 3TNF GNP 0.000005266 0.52812 5.74713
234 3QBT GNP 0.000005461 0.51175 5.74713
235 4LHW GNP 0.0000151 0.49486 5.74713
236 2A5J GDP 0.0004276 0.47504 5.75916
237 1JJ7 ADP 0.00002262 0.57347 5.76923
238 4NON GDP 0.0007534 0.41652 5.76923
239 2C5L GTP 0.000006622 0.50034 5.78035
240 2WKQ GTP 0.000007661 0.52016 5.79268
241 1SKQ GDP 0.0001795 0.51121 5.79268
242 4ZG4 VO4 ADP 0.00001964 0.50325 5.79268
243 1FNN ADP 0.0004876 0.45802 5.79268
244 1AQU A3P 0.001001 0.40721 5.79268
245 4K81 GTP 0.00001347 0.51132 5.84795
246 5XCO GDP 0.0004508 0.4106 5.84795
247 1GWN GTP 0.000004947 0.50322 5.85366
248 4Z7X 3CX 0.03638 0.406 5.88235
249 5O2T GSP 0.000007957 0.49748 5.91716
250 3RWO GDP 0.0002311 0.45685 5.94595
251 4KVG GTP 0.000004589 0.52625 5.95238
252 1VHT BA3 0.002011 0.44349 5.9633
253 3X1Z GNP 0.000008528 0.48808 5.98802
254 3UIE ANP 0.0006209 0.46744 6
255 3DDC GNP 0.000006634 0.50005 6.0241
256 5UFQ GNP 0.00007688 0.46709 6.0241
257 3KUD GDP 0.0003042 0.46251 6.0241
258 3KTA AP5 0.001867 0.44058 6.04396
259 3WXM GTP 0.000006796 0.5193 6.09756
260 3VMF GTP 0.000006927 0.51896 6.09756
261 5MZN ADP 0.00215 0.46238 6.09756
262 1IHU AF3 0.001699 0.42669 6.09756
263 1IHU ADP 0.001813 0.422 6.09756
264 5JCZ GDP 0.0001078 0.48681 6.14525
265 3Q9L ATP 0.0006389 0.45729 6.15385
266 1X1R GDP 0.0008242 0.42082 6.17978
267 1ZC3 GNP 0.00001325 0.50957 6.19469
268 5KSP GDP 0.0004395 0.47985 6.31579
269 5CK5 GDP 0.00006768 0.53258 6.32911
270 4IEE AGS 0.0005541 0.48653 6.40244
271 5LB3 ADP 0.0008997 0.47591 6.40244
272 1OYY AGS 0.002486 0.44851 6.40244
273 4PJ3 ANP 0.002788 0.43259 6.40244
274 1ZJ6 G3D 0.0002423 0.49227 6.41711
275 4QM7 GTP 0.0003854 0.48835 6.43275
276 4RZ3 ADP 0.001146 0.4459 6.44068
277 5DI3 GNP 0.000007434 0.52615 6.48649
278 1B0U ATP 0.005652 0.41849 6.48855
279 1M7B GTP 0.000002831 0.54989 6.52174
280 3AQ4 GDP 0.0001957 0.49672 6.52174
281 3GJ8 GDP 0.0003377 0.48534 6.52174
282 3FYH ADP 0.004723 0.40177 6.52174
283 3A4M ADP 0.0000704 0.53926 6.53846
284 1F6B GDP 0.0002359 0.49282 6.56566
285 5TDC NMM ILE PHE SER 0.02573 0.40898 6.57895
286 2QTV GNP 0.000008357 0.5134 6.58683
287 1KAO GDP 0.001294 0.44353 6.58683
288 1MR3 G3D 0.0004156 0.40096 6.62983
289 4R2I ANP 0.004124 0.44771 6.66667
290 5L3V GDP 0.0002361 0.48714 6.68896
291 1Z0F GDP 0.0002722 0.48984 6.70391
292 3A1S GDP 0.00004723 0.52636 6.70732
293 4LJ9 ACP 0.008171 0.42304 6.70732
294 5L3S GNP 0.0003735 0.44649 6.71141
295 1S8F GDP 0.0001459 0.44341 6.77966
296 3PCR GTP 0.000007508 0.52052 6.79012
297 4QOS ADP 0.0004498 0.47401 6.79245
298 4BQS ADP 0.0004572 0.4847 6.81818
299 1NRJ GTP 0.00001492 0.48591 6.88073
300 3BIB PSF 0.01173 0.41711 6.89655
301 2WJG GDP 0.00007071 0.52457 6.91489
302 1ZD9 GDP 0.0002986 0.46738 6.91489
303 4YLG GDP 0.0001588 0.48442 6.93642
304 3B7G ANP 0.0003025 0.48764 6.95652
305 2BME GNP 0.000002927 0.53421 6.98925
306 5JCP GDP ALF 0.00002066 0.52415 7.0122
307 1DNP MHF 0.02775 0.41896 7.0122
308 4NZ6 DGL 0.02073 0.41386 7.0122
309 1UPT GTP 0.000007301 0.5035 7.01754
310 2IYL GDP 0.0004128 0.48688 7.04225
311 4M9Q GNP 0.000004334 0.53603 7.04846
312 2CHG ANP 0.001378 0.4423 7.07965
313 1CR1 TTP 0.0005246 0.42498 7.09459
314 4KAX GTP 0.000004967 0.51 7.10059
315 1Z2A GDP 0.0002056 0.4611 7.14286
316 3CPJ GDP 0.0005917 0.40513 7.17489
317 3PQC GDP 0.00002977 0.52932 7.17949
318 1O3Y GTP 0.000005335 0.52665 7.22892
319 2J59 GTP 0.000005379 0.5265 7.22892
320 1J2J GTP 0.00000613 0.52416 7.22892
321 3DEF GDP 0.00001445 0.53741 7.25191
322 1R4A GNP 0.000008313 0.51349 7.27273
323 1FQJ ALF 0.00002222 0.57057 7.31707
324 1V8K ANP 0.0001396 0.51004 7.31707
325 4B47 GDP 0.0002249 0.50628 7.31707
326 4R43 GDP 0.0004213 0.48645 7.31707
327 1S9D GDP 0.0003412 0.48513 7.31707
328 1FQJ GDP 0.0001521 0.46651 7.31707
329 4MKF AP5 0.003538 0.42652 7.31707
330 4MKG AP5 0.003833 0.42396 7.31707
331 4CVN ADP 0.0001448 0.52304 7.32984
332 3N5C GDP 0.0001452 0.5092 7.40741
333 5H67 ATP 0.01083 0.41293 7.44681
334 2F9L GDP 0.0003498 0.45156 7.53769
335 1TU3 GNP 0.000008046 0.51631 7.60234
336 4ZKD GDP 0.00001738 0.48501 7.62195
337 1R2Q GNP 0.00001141 0.44566 7.64706
338 4R98 GNH 0.00009558 0.51813 7.74908
339 2W83 GTP 0.00000544 0.5263 7.79221
340 3B5J 12D 0.0002829 0.50799 7.81893
341 2WJH FLC 0.00001487 0.45379 7.83133
342 2WJH GDP 0.00003123 0.43698 7.83133
343 1OIX GDP 0.00001218 0.49846 7.8534
344 1OIV GDP 0.000131 0.46691 7.8534
345 4U5X GNP 0.00002029 0.47191 7.86517
346 4YMU ATP 0.0001608 0.51363 7.91667
347 4A4Z ANP 0.001422 0.46046 7.92683
348 3CV2 OXL 0.04007 0.40709 7.92683
349 3R7F CP 0.02945 0.40529 7.92683
350 2QG6 NMN 0.001396 0.40481 8.0402
351 5WDR GNP 0.000006697 0.49973 8.18713
352 3M1I GTP 0.000004717 0.52796 8.21918
353 3IIJ ADP 0.0001197 0.51333 8.33333
354 3WYF GTP 0.000007109 0.52275 8.40336
355 4LX0 BEF GDP 0.000007887 0.51881 8.47458
356 3ZS9 ADP ALF 0.000311 0.43603 8.53659
357 2WOJ ADP ALF 0.000373 0.43485 8.53659
358 4XVU ATP 0.001705 0.42311 8.53659
359 1GUA GNP 0.000008863 0.49535 8.64198
360 4C4P GNP 0.0000193 0.50288 8.67052
361 1VG8 GNP 0.000005356 0.5257 8.69565
362 1WA5 GTP 0.000005954 0.47364 9.09091
363 3WYG GTP 0.000004654 0.49871 9.21053
364 5H56 TYD 0.002258 0.42262 9.23077
365 5H56 ADP 0.002258 0.42262 9.23077
366 2WIC GNP 0.00001707 0.54757 9.3633
367 1VG9 GDP 0.0008415 0.40035 9.45122
368 4OI4 ATP 0.002243 0.41818 9.56522
369 2BEK ATP 0.0008121 0.44021 9.72763
370 1Y63 ADP 0.00005467 0.53006 9.78261
371 4DID GDP 0.0005401 0.47555 9.84456
372 1KY3 GDP 0.0001585 0.42631 9.89011
373 4ITR GDP 0.00071 0.41583 9.94764
374 2WMO GTP 0.00001213 0.5476 10
375 4HDO GNP 0.000007368 0.49845 10.061
376 2W2X GSP 0.000001839 0.51789 10.2703
377 2A5F GTP 0.000009435 0.51127 10.2857
378 3T12 GDP ALF 0.000006906 0.5275 10.2941
379 1TQ4 GDP 0.0005738 0.45065 10.3659
380 1H65 GDP 0.0001906 0.46675 10.3704
381 1E96 GTP 0.000009192 0.50294 10.4167
382 1I4D GDP 0.0005864 0.48529 10.4167
383 4YC7 GNP 0.000006105 0.50563 10.4972
384 5EE5 GTP 0.00000599 0.53011 10.5263
385 1G7C 5GP 0.003387 0.4419 10.6383
386 3SBD GNP 0.000008854 0.50357 10.6952
387 1MH1 GNP 0.00003245 0.474 10.7527
388 1G4U AF3 0.0001694 0.52978 10.8696
389 1G4U GDP 0.0008725 0.44692 10.8696
390 1G3Q ADP 0.001654 0.45221 10.9705
391 3BD9 A3P 0.00546 0.42727 11.0714
392 1YZG GDP 0.0001991 0.41046 11.1732
393 2FJU GSP 0.000002013 0.5157 11.236
394 5E95 GDP 0.002251 0.43274 11.3402
395 1PUJ GNP 0.00001264 0.46494 11.3475
396 1M7G ADP 0.001925 0.42403 11.3744
397 1M7G ADX 0.002638 0.4212 11.3744
398 1M7G AV2 0.00009657 0.41045 11.3744
399 5MEX SZZ 0.00624 0.41269 11.5854
400 5MEX PAP 0.001281 0.40698 11.5854
401 2GCO GNP 0.00001316 0.4704 11.9403
402 2GCN GDP 0.0002897 0.44029 11.9403
403 3GFS FMN 0.01227 0.40655 12.069
404 3DOE GTP 0.000004479 0.52979 12.1212
405 2W58 ADP 0.000004057 0.62226 12.3762
406 5HPY GDP 0.000192 0.42899 12.4324
407 3GJX GTP 0.000007266 0.52027 12.5
408 2UZI GTP 0.000006495 0.5201 12.5
409 3LXR GDP 0.0009399 0.45899 12.5
410 1W7J ADP BEF 0.0002844 0.47307 12.5828
411 1HE1 AF3 0.00008841 0.53414 12.5926
412 1HE1 GDP 0.0003143 0.4619 12.5926
413 2X77 GDP 0.0001743 0.49913 12.6984
414 4XOI GTP 0.000008207 0.51372 12.7778
415 4XSH GSP 0.00002161 0.51747 12.8492
416 3GJ7 GDP 0.0002185 0.50047 13.2653
417 3CNL GNP 0.00001295 0.56879 13.3588
418 1XMV ADP 0.0003978 0.40001 13.4146
419 4XTR ADP 0.001343 0.43868 13.5135
420 4XTR ATP 0.00157 0.4246 13.5135
421 4V0K GDP 0.002406 0.41367 13.6095
422 1KSH GDP 0.00001323 0.48675 13.8158
423 3T5G GDP 0.000397 0.40559 13.8158
424 5TB5 GDP 0.0007964 0.46237 14
425 5TAR GDP 0.001099 0.45113 14.1892
426 4D0G GTP 0.00004474 0.49329 14.4928
427 3BC1 GNP 0.00001232 0.49828 14.8718
428 1XP8 AGS 0.0008738 0.47655 15.3005
429 5J1S ATP 0.001074 0.42788 15.4472
430 1BO4 COA 0.01012 0.41845 15.4762
431 5N69 ADP 0.0001454 0.49143 17.0854
432 3GJ5 GDP 0.0003743 0.4832 17.6471
433 4ZI2 GNP 0.000002965 0.54298 17.8947
434 4GOJ GNP 0.000003354 0.51653 17.9894
435 1PTR PRB 0.03009 0.40159 18
436 1FZQ GDP 0.0000929 0.51874 18.7845
437 1Z0K GTP 0.000005128 0.52736 18.8406
438 2V7Q ATP 0.0001776 0.49294 19.697
439 2V7Q ADP 0.0003397 0.49104 19.697
440 2GOO NDG 0.03135 0.40725 20.1754
441 3GJ4 GDP 0.000202 0.50215 21.2121
442 2VB6 ADP BEF 0.0008002 0.4367 23.4899
443 3CH5 GDP 0.0004651 0.47867 25
444 4HDQ GNP 0.00001036 0.51395 26.9231
445 1Z0J GTP 0.000007681 0.49785 27.1186
446 3WY9 GDP 0.0003767 0.49499 28.125
447 3ZIA ADP 0.0001727 0.42439 30.1587
448 3ZIA ATP 0.0001175 0.41368 30.1587
449 3MJH GTP 0.000005696 0.51113 32.3529
450 4IDN GNP 0.0000000014 0.6832 33.2317
451 5VGR GDP 0.0000004679 0.59795 37.8049
452 3QF7 ANP 0.007355 0.40255 38
Pocket No.: 2; Query (leader) PDB : 2B8W; Ligand: ALF 5GP; Similar sites found: 11
This union binding pocket(no: 2) in the query (biounit: 2b8w.bio1) has 25 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 4WXJ GLU 0.02288 0.40898 1.48699
2 2ZJ5 ADP 0.03602 0.40164 2.13415
3 2JFZ DGL 0.02304 0.40428 2.7451
4 2JFZ 003 0.02556 0.40222 2.7451
5 1B74 DGN 0.04047 0.4023 3.14961
6 4MRP GSH 0.04138 0.4006 3.65854
7 2UVO NAG 0.03388 0.40299 4.09357
8 3OEN GLU 0.02338 0.40043 4.8951
9 1APZ ASP 0.03302 0.40062 6.79012
10 3ZW0 FUC 0.02211 0.41292 8.04598
11 1VBO MAN MAN MAN 0.008158 0.44246 9.39597
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